{"meta":{"built":"2026-11-02","guidelines_found":23300,"guidelines_used":18001,"lineages":15621,"papers":6541,"years":[2011,2026]},"areas":["Cardiology","Oncology","Infectious Disease","Pulmonology","Gastroenterology & Hepatology","Neurology","Psychiatry","Endocrinology & Metabolism","Nephrology & Urology","Obstetrics & Gynecology","Hematology","Rheumatology","Allergy & Immunology","Orthopedics & Trauma","Dermatology","Ophthalmology","ENT & Oral Health","Neonatal & Genetic"],"designs":["Meta-analysis","Systematic review","RCT","Other trial","Consensus","Observational","Review","Other"],"years":[2011,2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024,2025,2026],"papers":[[19717844,"Dabigatran versus warfarin in patients with atrial fibrillation.","N Engl J Med",2009,"Connolly et al.",2,[0],[143.57],148.91,140,97,51,[10,7,12,12,5,12,5,13,5,3,5,4,1,9,5,2],"10.1056/NEJMoa0905561"],[11832527,"Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.","N Engl J Med",2002,"Knowler et al.",2,[7],[114.74],145.35,117,89,52,[10,4,15,8,9,4,2,12,4,6,4,2,2,8,4,4],"10.1056/NEJMoa012512"],[21870978,"Apixaban versus warfarin in patients with atrial fibrillation.","N Engl J Med",2011,"Granger et al.",2,[0,5],[127.77,51.83],137.32,119,82,49,[1,7,8,9,5,11,5,14,5,5,5,4,1,9,3,2],"10.1056/NEJMoa1107039"],[21830957,"Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.","N Engl J Med",2011,"Patel et al.",2,[0],[131.71],137.05,120,82,49,[1,7,12,10,5,12,4,14,5,2,5,3,2,9,3,1],"10.1056/NEJMoa1009638"],[26378978,"Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.","N Engl J Med",2015,"Zinman et al.",2,[0,7],[73.71,84.15],124.55,105,78,46,[0,0,0,0,0,7,7,9,7,14,4,7,6,13,6,10],"10.1056/NEJMoa1504720"],[19482214,"Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials.","Lancet",2009,"Baigent et al.",0,[0],[92.72],123.75,116,79,43,[10,12,7,10,3,7,4,10,6,6,2,4,2,7,3,4],"10.1016/S0140-6736(09)60503-1"],[21714641,"Reduced lung-cancer mortality with low-dose computed tomographic screening.","N Engl J Med",2011,"Aberle et al.",2,[1,3],[112.6,110.32],123.21,78,68,47,[0,4,9,7,8,6,12,4,0,2,7,0,4,4,5,3],"10.1056/NEJMoa1102873"],[9742976,"Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.","Lancet",1998,"",2,[7],[102.56],122.23,93,70,49,[6,7,12,11,6,11,8,2,2,3,1,1,3,6,0,0],""],[18539916,"Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.","N Engl J Med",2008,"Patel et al.",2,[7],[85.17],117.7,105,68,48,[8,8,12,11,2,6,6,4,1,7,2,3,3,5,1,2],"10.1056/NEJMoa0802987"],[26551272,"A Randomized Trial of Intensive versus Standard Blood-Pressure Control.","N Engl J Med",2015,"Wright et al.",2,[0],[98.38],116.37,115,84,42,[0,0,0,0,0,9,7,11,9,6,6,6,9,14,8,7],"10.1056/NEJMoa1511939"],[19318384,"Intensive versus conventional glucose control in critically ill patients.","N Engl J Med",2009,"Finfer et al.",2,[7],[59.29],115.8,90,61,44,[14,10,8,4,5,3,4,6,4,5,0,3,2,2,3,2],"10.1056/NEJMoa0810625"],[8366922,"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.","N Engl J Med",1993,"Nathan et al.",2,[7,0,15],[95.07,35.61,14.69],112.88,93,69,39,[6,5,13,16,4,5,6,10,3,5,2,2,3,3,2,1],"10.1056/NEJM199309303291401"],[21067804,"Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.","Lancet",2010,"Baigent et al.",0,[0,5],[85.3,4.65],112.82,132,81,40,[5,4,8,11,5,4,6,5,12,4,3,6,4,7,5,4],"10.1016/S0140-6736(10)61350-5"],[18539917,"Effects of intensive glucose lowering in type 2 diabetes.","N Engl J Med",2008,"Gerstein et al.",2,[7],[83.94],111.4,94,64,45,[10,8,11,9,1,5,4,2,2,5,3,4,1,5,2,2],"10.1056/NEJMoa0802743"],[20228401,"Effects of intensive blood-pressure control in type 2 diabetes mellitus.","N Engl J Med",2010,"Cushman et al.",2,[0,7],[81.48,49.15],109.07,82,58,42,[5,3,4,7,7,3,1,3,6,6,4,3,3,7,4,3],"10.1056/NEJMoa1001286"],[17982182,"Prasugrel versus clopidogrel in patients with acute coronary syndromes.","N Engl J Med",2007,"Wiviott et al.",2,[0],[98.18],108.42,111,71,41,[10,11,11,6,6,8,4,10,5,3,0,4,2,5,1,0],"10.1056/NEJMoa0706482"],[12117397,"Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial.","JAMA",2002,"Rossouw et al.",2,[0,1],[45.02,34.0],103.95,75,61,38,[10,4,6,7,4,2,2,3,2,2,9,3,0,6,5,2],"10.1001/jama.288.3.321"],[27295427,"Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.","N Engl J Med",2016,"Marso et al.",2,[7,0],[71.76,51.22],101.51,81,65,37,[0,0,0,0,0,2,5,10,6,11,5,5,3,8,7,12],"10.1056/NEJMoa1603827"],[18784090,"10-year follow-up of intensive glucose control in type 2 diabetes.","N Engl J Med",2008,"Holman et al.",2,[7,0],[86.88,36.46],97.76,85,57,38,[7,5,7,7,3,6,5,3,2,5,5,2,2,6,1,2],"10.1056/NEJMoa0806470"],[24251359,"Edoxaban versus warfarin in patients with atrial fibrillation.","N Engl J Med",2013,"Giugliano et al.",2,[0,5],[93.42,30.64],97.16,80,55,35,[0,1,1,5,3,11,4,12,5,4,4,3,1,6,2,2],"10.1056/NEJMoa1310907"],[19717846,"Ticagrelor versus clopidogrel in patients with acute coronary syndromes.","N Engl J Med",2009,"Wallentin et al.",2,[0],[88.58],95.54,97,64,35,[7,10,9,7,5,9,3,9,3,4,0,3,1,6,2,0],"10.1056/NEJMoa0904327"],[11253156,"Frailty in older adults: evidence for a phenotype.","J Gerontol A Biol Sci Med Sci",2001,"Fried et al.",5,[5,13],[8.47,2.69],91.17,55,45,36,[0,3,3,1,2,3,5,2,9,3,0,2,3,5,5,1],"10.1093/gerona/56.3.m146"],[26039521,"Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.","N Engl J Med",2015,"Cannon et al.",2,[0],[67.96],90.78,90,62,33,[0,0,0,0,2,8,4,8,9,5,6,7,4,6,6,8],"10.1056/NEJMoa1410489"],[11794168,"Intensive insulin therapy in critically ill patients.","N Engl J Med",2001,"van den Berghe et al.",2,[7],[46.11],90.29,75,48,36,[11,7,7,3,6,3,4,5,3,3,0,3,1,2,2,1],"10.1056/NEJMoa011300"],[24315724,"Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials.","Lancet",2014,"Ruff et al.",0,[0],[74.79],89.82,62,50,34,[0,0,0,1,1,9,2,10,5,2,3,3,2,10,5,1],"10.1016/S0140-6736(13)62343-0"],[26095867,"Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.","N Engl J Med",2015,"Douketis et al.",2,[0],[79.57],88.54,59,45,36,[0,0,0,0,1,8,4,7,5,4,4,3,2,4,4,3],"10.1056/NEJMoa1501035"],[28304224,"Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.","N Engl J Med",2017,"Sabatine et al.",2,[0,7],[70.71,48.52],88.44,81,61,35,[0,0,0,0,0,0,2,11,11,6,7,9,5,7,3,8],"10.1056/NEJMoa1615664"],[19092145,"Glucose control and vascular complications in veterans with type 2 diabetes.","N Engl J Med",2009,"Duckworth et al.",2,[7,0],[68.24,40.13],87.66,78,50,38,[7,6,9,8,1,6,5,3,4,5,0,2,1,3,0,1],"10.1056/NEJMoa0808431"],[11786451,"Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients.","BMJ",2002,"Antithrombotic Trialists' Collaboration",0,[0,5],[85.25,16.89],87.63,112,62,30,[12,12,6,7,4,2,5,6,3,3,4,3,3,3,3,1],"10.1136/bmj.324.7329.71"],[20818875,"Early palliative care for patients with metastatic non-small-cell lung cancer.","N Engl J Med",2010,"Temel et al.",2,[1,3],[75.52,26.71],87.12,62,46,36,[2,4,10,5,3,2,5,3,4,0,0,1,4,4,3,5],"10.1056/NEJMoa1000678"],[18378520,"Telmisartan, ramipril, or both in patients at high risk for vascular events.","N Engl J Med",2008,"Yusuf et al.",2,[0,7],[60.98,30.43],86.47,96,58,32,[3,5,8,10,3,7,5,3,1,3,4,2,0,6,5,5],"10.1056/NEJMoa0801317"],[27633186,"Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.","N Engl J Med",2016,"Marso et al.",2,[7,0],[63.84,42.74],86.46,66,54,33,[0,0,0,0,0,1,1,4,5,8,4,6,2,14,7,9],"10.1056/NEJMoa1607141"],[20299623,"A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey.","Chest",2010,"Pisters et al.",5,[0],[76.8],86.22,68,49,32,[1,6,4,10,0,6,1,3,5,2,2,3,2,4,2,4],"10.1378/chest.10-0134"],[12493255,"Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.","Lancet",2002,"Lewington et al.",0,[0],[81.76],85.89,83,54,31,[5,8,3,4,2,6,1,3,4,1,5,2,3,7,3,3],"10.1016/s0140-6736(02)11911-8"],[18046031,"Computed tomography--an increasing source of radiation exposure.","N Engl J Med",2007,"Brenner et al.",6,[1,13],[24.65,10.87],84.8,48,41,35,[7,0,2,6,3,8,2,2,3,1,1,1,3,2,0,2],"10.1056/NEJMra072149"],[11565518,"Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.","N Engl J Med",2001,"Brenner et al.",2,[8,7,0],[47.13,49.27,45.44],84.63,64,46,32,[2,3,5,5,3,3,2,0,4,3,4,3,2,4,5,5],"10.1056/NEJMoa011161"],[28605608,"Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes.","N Engl J Med",2017,"Neal et al.",2,[0,7,8],[52.19,55.48,20.55],83.05,72,55,33,[0,0,0,0,0,0,0,6,7,11,5,6,5,11,5,8],"10.1056/NEJMoa1611925"],[11565517,"Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes.","N Engl J Med",2001,"Lewis et al.",2,[7,8],[46.11,52.64],82.63,58,44,31,[3,3,5,4,2,1,0,0,4,3,2,3,2,5,6,6],"10.1056/NEJMoa011303"],[9635947,"Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group.","Lancet",1998,"Hansson et al.",2,[0],[61.7],81.99,67,44,31,[5,3,7,6,4,4,3,6,3,2,1,3,1,3,1,3],"10.1016/s0140-6736(98)04311-6"],[8918275,"A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.","Lancet",1996,"CAPRIE Steering Committee",2,[0,5],[72.33,16.55],81.88,101,57,29,[8,12,7,8,1,4,3,4,2,2,3,1,1,9,2,1],"10.1016/s0140-6736(96)09457-3"],[23281973,"Transfusion strategies for acute upper gastrointestinal bleeding.","N Engl J Med",2013,"Villanueva et al.",2,[4],[57.32],81.72,43,42,32,[0,0,1,2,5,6,4,3,4,5,5,1,2,1,4,0],"10.1056/NEJMoa1211801"],[18650514,"Sorafenib in advanced hepatocellular carcinoma.","N Engl J Med",2008,"Llovet et al.",2,[4,1],[75.94,75.19],80.65,54,42,32,[5,7,2,2,2,3,2,3,2,3,3,5,1,7,2,0],"10.1056/NEJMoa0708857"],[26903338,"The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).","JAMA",2016,"Singer et al.",4,[2],[50.01],80.12,43,39,36,[0,0,0,0,0,0,3,6,7,6,4,3,2,4,3,2],"10.1001/jama.2016.0287"],[9971864,"A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.","N Engl J Med",1999,"Hébert et al.",2,[10],[34.94],79.43,43,38,32,[4,5,8,2,3,2,1,2,1,3,0,2,1,1,4,0],"10.1056/NEJM199902113400601"],[30990260,"Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.","N Engl J Med",2019,"Perkovic et al.",2,[7,8,0],[56.46,40.44,35.53],79.17,61,51,32,[0,0,0,0,0,0,0,0,2,11,8,6,4,12,4,8],"10.1056/NEJMoa1811744"],[26095746,"Idarucizumab for Dabigatran Reversal.","N Engl J Med",2015,"Pollack et al.",3,[0],[64.05],78.88,49,37,34,[0,1,0,0,3,9,2,9,3,2,2,4,1,2,1,1],"10.1056/NEJMoa1502000"],[15364185,"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study.","Lancet",2004,"Yusuf et al.",5,[0],[59.85],78.77,66,46,30,[3,7,7,2,0,4,3,4,2,2,4,3,2,1,2,5],"10.1016/S0140-6736(04)17018-9"],[16371630,"Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.","N Engl J Med",2005,"Nathan et al.",2,[7,0],[63.21,29.63],76.7,75,44,32,[7,3,10,9,4,2,1,3,1,5,3,2,0,1,3,1],"10.1056/NEJMoa052187"],[12853587,"Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer.","N Engl J Med",2003,"Lee et al.",2,[0,1,3],[71.68,42.76,22.97],76.32,50,45,26,[6,4,7,3,4,3,0,3,1,1,7,0,2,3,2,2],"10.1056/NEJMoa025313"],[21663949,"The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.","Lancet",2011,"Baigent et al.",2,[0,8],[37.46,23.76],76.3,60,42,32,[0,6,3,7,3,2,1,3,6,1,3,4,0,2,1,4],"10.1016/S0140-6736(11)60739-3"],[10471456,"The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators.","N Engl J Med",1999,"Pitt et al.",2,[0],[65.74],76.27,88,53,25,[2,5,7,5,5,7,4,5,4,4,4,4,1,1,2,2],"10.1056/NEJM199909023411001"],[11556941,"The PHQ-9: validity of a brief depression severity measure.","J Gen Intern Med",2001,"Kroenke et al.",7,[],[],75.34,41,37,31,[0,1,1,3,2,2,0,4,2,2,5,1,4,1,5,5],"10.1046/j.1525-1497.2001.016009606.x"],[23045170,"2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides.","Arthritis Rheum",2013,"Jennette et al.",4,[0,11],[62.79,54.87],74.39,42,37,29,[0,0,1,1,1,4,4,1,2,2,3,2,5,2,6,4],"10.1002/art.37715"],[11519503,"Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.","N Engl J Med",2001,"Yusuf et al.",2,[0],[62.46],73.83,74,48,27,[7,11,7,4,5,4,2,5,2,1,2,1,1,2,1,0],"10.1056/NEJMoa010746"],[11136953,"Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group.","N Engl J Med",2001,"Sacks et al.",2,[0],[55.61],72.31,78,47,28,[5,5,6,7,1,5,1,3,3,4,2,2,1,4,4,4],"10.1056/NEJM200101043440101"],[11333990,"Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.","N Engl J Med",2001,"Tuomilehto et al.",2,[7],[62.51],71.64,55,39,30,[5,3,7,4,6,1,1,5,0,1,4,1,0,3,0,2],"10.1056/NEJM200105033441801"],[20393175,"Infliximab, azathioprine, or combination therapy for Crohn's disease.","N Engl J Med",2010,"Colombel et al.",2,[4],[70.69],70.69,47,43,23,[3,3,3,5,2,1,4,5,4,2,3,0,2,5,5,0],"10.1056/NEJMoa0904492"],[18378519,"Treatment of hypertension in patients 80 years of age or older.","N Engl J Med",2008,"Beckett et al.",2,[0,5],[63.9,3.1],70.33,58,42,27,[2,3,5,6,6,8,1,2,2,2,0,2,1,2,1,2],"10.1056/NEJMoa0801369"],[19762550,"Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation.","Chest",2010,"Lip et al.",5,[0,5],[69.12,35.18],70.29,69,45,24,[1,7,5,6,1,7,3,2,3,2,4,2,2,6,2,0],"10.1378/chest.09-1584"],[19144931,"A surgical safety checklist to reduce morbidity and mortality in a global population.","N Engl J Med",2009,"Haynes et al.",5,[],[],70.13,36,33,27,[2,4,1,3,3,2,3,3,1,3,1,1,3,1,3,1],"10.1056/NEJMsa0810119"],[6880820,"The hospital anxiety and depression scale.","Acta Psychiatr Scand",1983,"Zigmond et al.",7,[6],[10.83],69.93,33,32,29,[2,2,2,4,6,1,0,1,3,2,3,2,3,1,0,1],"10.1111/j.1600-0447.1983.tb09716.x"],[16129869,"A global clinical measure of fitness and frailty in elderly people.","CMAJ",2005,"Rockwood et al.",5,[],[],69.48,40,36,29,[0,0,3,1,1,0,6,1,5,3,3,2,1,4,2,4],"10.1503/cmaj.050051"],[19414839,"A new equation to estimate glomerular filtration rate.","Ann Intern Med",2009,"Levey et al.",5,[8],[45.8],68.92,36,34,27,[1,1,1,5,3,1,2,4,3,2,0,1,2,3,3,2],"10.7326/0003-4819-150-9-200905050-00006"],[18997196,"Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.","N Engl J Med",2008,"Ridker et al.",2,[0],[56.15],68.86,65,43,24,[6,2,3,10,3,4,1,3,8,1,2,4,0,2,2,2],"10.1056/NEJMoa0807646"],[10477528,"Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery.","Circulation",1999,"Lee et al.",5,[0],[35.01],68.85,43,35,25,[2,2,3,4,3,2,3,3,1,2,1,1,2,2,2,4],"10.1161/01.cir.100.10.1043"],[30415628,"Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.","N Engl J Med",2019,"Bhatt et al.",2,[0,7],[49.58,53.1],68.67,60,48,28,[0,0,0,0,0,0,0,0,5,7,5,6,3,10,5,11],"10.1056/NEJMoa1812792"],[16928254,"The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus.","Am J Gastroenterol",2006,"Vakil et al.",1,[4],[54.39],67.86,35,30,30,[1,2,1,1,3,5,1,2,0,2,1,2,1,2,4,5],"10.1111/j.1572-0241.2006.00630.x"],[9742977,"Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). 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Prophylaxis in Medical Patients with Enoxaparin Study Group.","N Engl J Med",1999,"Samama et al.",2,[0,3],[45.8,4.65],54.39,32,27,26,[2,2,7,2,1,1,1,2,0,5,3,1,0,1,1,0],"10.1056/NEJM199909093411103"],[20483451,"Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.","Lancet",2010,"Matsushita et al.",0,[0,8],[29.54,25.06],54.24,39,30,22,[1,2,5,1,0,3,2,1,4,0,2,1,1,4,2,1],"10.1016/S0140-6736(10)60674-5"],[7477192,"Tissue plasminogen activator for acute ischemic stroke.","N Engl J Med",1995,"National Institute of Neurological Disor",2,[0,5],[54.2,50.12],54.2,38,28,20,[4,4,6,1,2,1,1,2,1,1,1,0,2,2,2,3],"10.1056/NEJM199512143332401"],[26888948,"The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation.","Ann Rheum Dis",2016,"Götestam Skorpen et al.",1,[11,9],[25.31,9.77],54.2,30,29,24,[0,0,0,0,0,0,1,0,6,2,1,2,4,5,7,1],"10.1136/annrheumdis-2015-208840"],[12114036,"MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.","Lancet",2002,"Heart Protection Study Collaborative Gro",2,[0,5],[39.18,6.32],54.13,64,37,21,[8,7,6,6,2,5,0,0,3,3,1,1,1,2,0,2],"10.1016/S0140-6736(02)09327-3"],[19095497,"Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial.","Lancet Oncol",2009,"Cheng et al.",2,[4,1],[54.11,51.83],54.11,39,28,23,[4,5,0,0,2,2,1,3,2,2,2,3,1,6,2,0],"10.1016/S1470-2045(08)70285-7"],[19683639,"Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial.","Lancet",2009,"Holmes et al.",2,[0,5],[53.99,30.41],53.99,45,32,20,[4,3,2,5,2,4,2,3,0,1,1,3,2,3,2,0],"10.1016/S0140-6736(09)61343-X"],[21252716,"International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.","J Thorac Oncol",2011,"Travis et al.",1,[1,3],[52.98,53.91],53.91,38,31,23,[0,5,8,4,3,3,4,3,1,0,0,0,1,1,2,1],"10.1097/JTO.0b013e318206a221"],[27299675,"Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.","N Engl J Med",2016,"Wanner et al.",2,[7,8],[46.78,23.68],53.64,35,30,23,[0,0,0,0,0,0,0,2,4,8,1,5,3,5,2,2],"10.1056/NEJMoa1515920"],[20573925,"Early use of TIPS in patients with cirrhosis and variceal bleeding.","N Engl J Med",2010,"García-Pagán et al.",2,[4],[53.63],53.63,28,28,20,[0,2,2,0,1,2,3,2,2,3,2,1,2,2,3,1],"10.1056/NEJMoa0910102"],[30146931,"Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.","N Engl J Med",2018,"Bowman et al.",2,[7,0],[23.68,35.99],53.53,30,28,26,[0,0,0,0,0,0,0,0,5,3,4,2,1,10,1,3],"10.1056/NEJMoa1804988"],[12479763,"Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).","JAMA",2002,"ALLHAT Officers and Coordinators for the",2,[0],[50.99],53.31,53,35,20,[6,3,4,4,2,5,3,3,3,2,0,1,0,2,2,2],"10.1001/jama.288.23.2981"],[29231094,"Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism.","N Engl J Med",2018,"Raskob et al.",2,[0,1],[47.91,34.45],52.97,32,29,23,[0,0,0,0,0,0,0,4,7,2,7,2,1,4,2,2],"10.1056/NEJMoa1711948"],[11856794,"Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.","N Engl J Med",2002,"Bernard et al.",2,[0,5],[47.98,17.76],52.69,39,33,18,[2,4,5,2,6,2,4,2,1,2,1,1,1,1,0,1],"10.1056/NEJMoa003289"],[19878986,"10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.","Lancet",2009,"Knowler et al.",2,[7],[46.95],52.55,35,25,22,[2,3,4,2,3,3,0,3,1,1,1,2,1,2,1,0],"10.1016/S0140-6736(09)61457-4"],[25865049,"Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis.","Gastroenterology",2015,"Vilar-Gomez et al.",5,[4],[45.12],52.26,36,28,24,[0,0,0,0,0,1,0,1,1,2,5,2,2,4,7,5],"10.1053/j.gastro.2015.04.005"],[15325833,"Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial.","Lancet",2004,"Colhoun et al.",2,[0,7],[39.5,42.66],52.23,67,35,18,[5,5,6,8,2,2,1,2,3,3,2,1,1,2,0,3],"10.1016/S0140-6736(04)16895-5"],[35120736,"Baveno VII - 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Results of the survival and ventricular enlargement trial. The SAVE Investigators.","N Engl J Med",1992,"Pfeffer et al.",2,[0],[49.37],51.72,61,40,16,[3,3,5,3,5,5,3,4,2,2,0,3,2,2,2,2],"10.1056/NEJM199209033271001"],[12788299,"Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project.","Eur Heart J",2003,"Conroy et al.",7,[0],[44.65],51.49,44,27,23,[2,2,3,2,3,3,2,2,3,0,1,3,0,1,0,1],"10.1016/s0195-668x(03)00114-3"],[15836656,"Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis.","J Intern Med",2005,"Burger et al.",0,[0],[36.42],51.49,36,25,22,[2,4,1,3,3,1,2,3,3,0,1,3,0,1,1,0],"10.1111/j.1365-2796.2005.01477.x"],[18184958,"Intensive insulin therapy and pentastarch resuscitation in severe sepsis.","N Engl J Med",2008,"Brunkhorst et al.",2,[2,7,8],[22.44,18.57,14.28],51.49,33,25,22,[6,3,4,1,1,4,2,1,1,1,1,3,0,2,0,0],"10.1056/NEJMoa070716"],[9459643,"A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prévention du Risque d'Embolie Pulmonaire par Interruption Cave Study Group.","N Engl J Med",1998,"Decousus et al.",2,[0,3,11],[51.43,21.24,0.0],51.43,30,27,21,[4,2,5,3,0,2,0,2,3,4,3,1,0,1,0,0],"10.1056/NEJM199802123380701"],[19446324,"Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial.","Lancet",2009,"Schweickert et al.",2,[5,6],[18.53,12.16],51.3,33,26,21,[0,0,5,2,2,1,4,3,0,4,1,2,0,2,2,1],"10.1016/S0140-6736(09)60658-9"],[1866765,"Atrial fibrillation as an independent risk factor for stroke: the Framingham Study.","Stroke",1991,"Wolf et al.",7,[0,5],[51.24,20.25],51.24,38,28,21,[5,2,3,3,1,4,3,2,0,0,2,1,0,3,2,1],"10.1161/01.str.22.8.983"],[17241859,"Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial.","Gastroenterology",2007,"Colombel et al.",2,[4],[51.22],51.22,31,28,19,[3,1,4,4,0,1,3,3,2,2,0,0,1,3,2,1],"10.1053/j.gastro.2006.11.041"],[16717171,"A brief measure for assessing generalized anxiety disorder: the GAD-7.","Arch Intern Med",2006,"Spitzer et al.",5,[6],[15.95],51.12,33,28,21,[1,0,0,3,0,1,0,2,2,3,4,2,4,3,2,2],"10.1001/archinte.166.10.1092"],[20427778,"Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.","N Engl J Med",2010,"Sanyal et al.",2,[4],[44.25],51.1,33,26,22,[0,2,1,1,2,1,0,2,1,3,4,3,0,1,4,3],"10.1056/NEJMoa0907929"],[29466156,"Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.","N Engl J Med",2018,"Drilon et al.",3,[1],[50.86],50.86,42,38,19,[0,0,0,0,0,0,0,1,1,3,5,6,4,9,11,2],"10.1056/NEJMoa1714448"],[15659722,"Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure.","N Engl J Med",2005,"Bardy et al.",2,[0],[47.76],50.67,67,46,14,[2,4,8,5,5,5,2,3,1,3,3,2,2,2,2,0],"10.1056/NEJMoa043399"],[21767103,"Prevention of HIV-1 infection with early antiretroviral therapy.","N Engl J Med",2011,"Cohen et al.",2,[2,9,12],[48.67,45.47,41.17],50.57,36,30,18,[1,6,4,8,4,2,2,0,4,1,2,0,0,0,1,1],"10.1056/NEJMoa1105243"],[18216292,"Development and validation of a predictive model for chemotherapy-associated thrombosis.","Blood",2008,"Khorana et al.",5,[0],[38.06],50.38,30,27,19,[2,1,4,3,3,0,0,2,4,4,2,1,1,1,0,2],"10.1182/blood-2007-10-116327"],[8413456,"The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group.","N Engl J Med",1993,"Lewis et al.",2,[8,7],[33.23,31.94],50.35,36,26,19,[3,2,3,4,2,0,1,1,2,3,2,3,3,0,1,3],"10.1056/NEJM199311113292004"],[16625125,"Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.","Crit Care Med",2006,"Kumar et al.",5,[2,0],[39.05,2.69],50.26,30,23,22,[2,2,2,0,2,2,4,1,2,3,1,0,0,2,3,0],"10.1097/01.CCM.0000217961.75225.E9"],[17035650,"Chronic health conditions in adult survivors of childhood cancer.","N Engl J Med",2006,"Oeffinger et al.",5,[1],[36.55],50.26,23,23,22,[0,2,3,0,1,4,1,1,1,3,3,1,2,0,1,0],"10.1056/NEJMsa060185"],[16009794,"Eight-year follow-up of patients with permanent vena cava filters in the prevention of pulmonary embolism: the PREPIC (Prevention du Risque d'Embolie Pulmonaire par Interruption Cave) randomized study.","Circulation",2005,"PREPIC Study Group",2,[0,3],[50.23,16.43],50.23,29,26,19,[3,3,2,2,1,1,0,1,2,4,4,1,1,2,0,1],"10.1161/CIRCULATIONAHA.104.512834"],[22920912,"Intraaortic balloon support for myocardial infarction with cardiogenic shock.","N Engl J Med",2012,"Thiele et al.",2,[0],[50.12],50.12,46,33,18,[0,0,0,4,7,2,1,3,2,1,3,0,2,2,7,2],"10.1056/NEJMoa1208410"],[18479744,"Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial.","Lancet",2008,"Devereaux et al.",2,[0],[40.16],50.09,40,27,19,[2,4,1,4,2,1,3,1,1,2,0,1,2,4,2,0],"10.1016/S0140-6736(08)60601-7"],[24206457,"Combined angiotensin inhibition for the treatment of diabetic nephropathy.","N Engl J Med",2013,"Fried et al.",2,[7,8],[24.97,20.77],50.04,37,27,20,[0,0,0,1,0,2,1,2,3,5,2,3,1,4,3,4],"10.1056/NEJMoa1303154"],[15470213,"Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer.","N Engl J Med",2004,"Tannock et al.",2,[1,8,9],[49.95,48.0,48.0],49.95,42,26,18,[1,4,4,2,4,5,0,3,1,3,2,2,3,3,3,1],"10.1056/NEJMoa040720"],[16298014,"Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies.","J Hepatol",2006,"D'Amico et al.",1,[4],[49.95],49.95,31,26,19,[1,1,2,1,2,0,2,2,2,1,5,2,1,2,3,1],"10.1016/j.jhep.2005.10.013"],[3317057,"Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study.","N Engl J Med",1987,"Schroeder et al.",2,[4],[46.65],49.77,30,26,20,[2,2,2,0,2,1,2,3,2,2,1,0,2,4,5,0],"10.1056/NEJM198712243172603"],[15128893,"Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.","N Engl J Med",2004,"Cooper et al.",2,[1],[49.77],49.77,28,26,19,[2,1,0,2,1,3,3,3,1,3,1,1,0,1,6,0],"10.1056/NEJMoa032646"],[2394349,"Predictability of the postoperative course of Crohn's disease.","Gastroenterology",1990,"Rutgeerts et al.",5,[4],[49.61],49.61,28,27,19,[2,1,1,2,1,0,4,3,3,0,1,0,1,4,5,0],"10.1016/0016-5085(90)90613-6"],[18256393,"Effect of a multifactorial intervention on mortality in type 2 diabetes.","N Engl J Med",2008,"Gaede et al.",2,[7,0],[38.74,30.23],49.61,43,27,22,[4,2,5,4,3,3,1,3,2,2,1,0,1,0,1,2],"10.1056/NEJMoa0706245"],[35732829,"The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.","Leukemia",2022,"Alaggio et al.",6,[10,1],[47.76,45.62],49.46,39,39,24,[0,0,0,0,0,0,0,0,0,0,0,0,8,12,12,7],"10.1038/s41375-022-01620-2"],[31682550,"Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study.","J Clin Oncol",2020,"Marabelle et al.",3,[1],[49.41],49.41,45,39,18,[0,0,0,0,0,0,0,0,0,1,5,5,11,9,9,4],"10.1200/JCO.19.02105"],[9099655,"A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group.","N Engl J Med",1997,"Appel et al.",2,[0],[35.13],49.39,58,37,18,[6,5,4,3,2,4,1,3,3,3,0,0,1,3,5,1],"10.1056/NEJM199704173361601"],[23992601,"Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus.","N Engl J Med",2013,"Scirica et al.",2,[7,0],[32.9,26.44],49.34,34,28,19,[0,0,0,1,2,6,3,3,4,3,2,1,0,4,0,2],"10.1056/NEJMoa1307684"],[1244564,"Prediction of creatinine clearance from serum creatinine.","Nephron",1976,"Cockcroft et al.",7,[8],[22.44],49.33,25,22,22,[2,2,5,4,1,2,2,2,0,0,1,0,0,2,1,1],"10.1159/000180580"],[11948273,"Hospital volume and surgical mortality in the United States.","N Engl J Med",2002,"Birkmeyer et al.",7,[1],[21.24],49.28,34,25,21,[5,2,2,1,2,0,3,2,3,0,1,0,1,4,1,0],"10.1056/NEJMsa012337"],[29368949,"Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition.","Cephalalgia",2018,"",7,[5],[34.65],49.0,37,35,19,[0,0,0,0,0,0,0,2,8,4,0,1,5,9,6,2],"10.1177/0333102417738202"],[20175033,"Modified RECIST (mRECIST) assessment for hepatocellular carcinoma.","Semin Liver Dis",2010,"Lencioni et al.",6,[1,4],[48.4,45.07],48.96,36,26,19,[1,3,4,0,2,2,3,1,1,2,1,4,2,1,2,2],"10.1055/s-0030-1247132"],[22449293,"Oral rivaroxaban for the treatment of symptomatic pulmonary embolism.","N Engl J Med",2012,"Büller et al.",2,[0,3],[48.95,18.53],48.95,30,25,20,[0,0,5,2,1,3,1,3,3,3,3,0,0,2,1,1],"10.1056/NEJMoa1113572"],[11589932,"Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.","Lancet",2001,"PROGRESS Collaborative Group",2,[0,5],[48.73,15.0],48.73,40,27,18,[3,3,2,1,4,2,2,3,1,0,0,1,1,2,2,2],"10.1016/S0140-6736(01)06178-5"],[28657417,"Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia.","N Engl J Med",2017,"Rolnik et al.",2,[9],[36.65],48.58,32,27,21,[0,0,0,0,0,0,0,2,4,4,2,3,2,5,4,2],"10.1056/NEJMoa1704559"],[17190893,"Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial.","JAMA",2006,"Black et al.",2,[13],[48.49],48.49,26,23,20,[1,1,4,1,0,1,2,0,3,3,0,3,2,2,1,1],"10.1001/jama.296.24.2927"],[10938048,"Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study.","BMJ",2000,"Stratton et al.",5,[7,0],[41.42,23.77],48.31,35,24,20,[4,4,2,6,1,3,2,1,1,2,1,1,0,3,0,1],"10.1136/bmj.321.7258.405"],[17715408,"Effects of bariatric surgery on mortality in Swedish obese subjects.","N Engl J Med",2007,"Sjöström et al.",5,[7,0],[39.38,6.74],48.27,33,25,20,[5,2,1,3,1,2,2,2,2,3,0,3,0,1,0,1],"10.1056/NEJMoa066254"],[29746227,"Comparison of an Oral Factor Xa Inhibitor With Low Molecular Weight Heparin in Patients With Cancer With Venous Thromboembolism: Results of a Randomized Trial (SELECT-D).","J Clin Oncol",2018,"Young et al.",2,[0,1],[41.94,33.88],48.21,29,26,21,[0,0,0,0,0,0,0,1,7,3,7,1,1,4,2,2],"10.1200/JCO.2018.78.8034"],[16452557,"Intensive insulin therapy in the medical ICU.","N Engl J Med",2006,"Van den Berghe et al.",2,[8],[3.39],48.17,41,26,21,[9,4,6,3,5,2,2,1,0,1,0,0,0,1,0,0],"10.1056/NEJMoa052521"],[16765759,"Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial.","Lancet",2006,"Connolly et al.",2,[0,5],[48.12,24.26],48.12,43,31,17,[6,6,3,5,1,4,2,4,0,1,1,1,0,2,0,0],"10.1016/S0140-6736(06)68845-4"],[17470824,"Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial.","Ann Intern Med",2007,"Sandborn et al.",2,[4],[43.59],48.08,28,27,18,[3,3,2,3,0,1,4,2,2,1,0,0,1,3,3,0],"10.7326/0003-4819-146-12-200706190-00159"],[35081280,"Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis.","N Engl J Med",2022,"Ytterberg et al.",2,[11,1,0],[14.25,3.41,1.0],48.02,31,31,23,[0,0,0,0,0,0,0,0,0,0,0,1,1,10,13,6],"10.1056/NEJMoa2109927"],[20410514,"A step-up approach or open necrosectomy for necrotizing pancreatitis.","N Engl J Med",2010,"van Santvoort et al.",2,[4],[41.4],48.0,25,23,21,[0,2,4,0,3,2,2,0,0,2,1,1,0,2,2,3],"10.1056/NEJMoa0908821"],[26028255,"PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.","N Engl J Med",2015,"Le et al.",3,[1],[47.93],47.93,44,33,18,[0,0,0,0,0,1,5,5,2,6,1,4,6,4,4,3],"10.1056/NEJMoa1500596"],[27144627,"Bowel Disorders.","Gastroenterology",2016,"Mearin et al.",7,[4],[33.22],47.93,32,27,21,[0,0,0,0,0,0,1,2,4,1,1,1,4,3,8,2],"10.1053/j.gastro.2016.02.031"],[10460813,"Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. 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al.",6,[1,10],[42.39,38.67],47.27,29,27,20,[0,0,0,0,0,0,3,2,2,3,2,3,3,4,4,2],"10.1182/blood-2016-01-643569"],[3558716,"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.","J Chronic Dis",1987,"Charlson et al.",5,[1],[14.77],47.25,27,24,19,[1,4,4,1,2,0,3,0,0,1,2,0,2,1,3,1],"10.1016/0021-9681(87)90171-8"],[19144937,"Fractional flow reserve versus angiography for guiding percutaneous coronary intervention.","N Engl J Med",2009,"Tonino et al.",2,[0],[47.25],47.25,53,34,15,[3,9,3,7,3,1,2,2,1,3,1,4,2,3,0,0],"10.1056/NEJMoa0807611"],[31838007,"Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials.","Lancet Oncol",2020,"Doebele et al.",7,[1],[47.23],47.23,43,38,18,[0,0,0,0,0,0,0,0,0,2,5,5,5,8,15,3],"10.1016/S1470-2045(19)30691-6"],[17192537,"An intervention to decrease catheter-related bloodstream infections in the ICU.","N Engl J Med",2006,"Pronovost et 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CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study.","Lancet",2012,"Pearce et al.",5,[1,13,5],[4.65,12.63,10.26],46.2,28,22,21,[0,1,2,2,2,2,2,3,0,1,0,1,2,2,1,1],"10.1016/S0140-6736(12)60815-0"],[17393509,"The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD.","Hepatology",2007,"Angulo et al.",7,[4],[36.09],46.05,29,22,20,[0,1,1,1,2,1,1,2,1,1,2,2,2,5,1,1],"10.1002/hep.21496"],[10517716,"Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators.","JAMA",1999,"Ettinger et al.",2,[13,7],[35.18,34.57],45.99,30,25,17,[3,2,3,1,2,1,2,1,4,1,0,2,0,3,3,1],"10.1001/jama.282.7.637"],[20460620,"Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial.","JAMA",2010,"Sanders et al.",2,[13],[35.49],45.98,26,22,19,[1,2,1,2,0,2,5,2,4,1,0,2,1,1,1,0],"10.1001/jama.2010.594"],[17387127,"Optimal medical therapy with or without PCI for stable coronary disease.","N Engl J Med",2007,"Boden et al.",2,[0],[45.96],45.96,64,38,13,[7,9,8,9,2,0,2,1,1,3,0,3,1,4,1,1],"10.1056/NEJMoa070829"],[30730782,"Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors.","N Engl J Med",2019,"Connolly et al.",7,[0,5,4],[40.28,17.42,5.29],45.86,34,27,22,[0,0,0,0,0,0,0,0,0,2,6,6,3,6,3,1],"10.1056/NEJMoa1814051"],[1798888,"A new method for measuring daytime sleepiness: the Epworth sleepiness scale.","Sleep",1991,"Johns",7,[5,6],[32.35,10.83],45.8,25,22,20,[0,0,1,2,1,3,6,1,0,0,0,1,2,2,1,2],"10.1093/sleep/14.6.540"],[20463339,"Quality indicators for colonoscopy and the risk of interval cancer.","N Engl J Med",2010,"Kaminski et al.",7,[1,4],[45.32,45.32],45.8,31,27,17,[0,6,3,2,0,3,2,1,0,1,3,1,1,3,1,0],"10.1056/NEJMoa0907667"],[4136544,"Assessment of coma and impaired consciousness. 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fibrillation by ectopic beats originating in the pulmonary veins.","N Engl J Med",1998,"Haïssaguerre et al.",7,[0],[41.92],41.92,44,28,14,[6,3,2,3,1,2,2,1,0,2,1,2,0,5,1,1],"10.1056/NEJM199809033391003"],[8464434,"The occurrence of sleep-disordered breathing among middle-aged adults.","N Engl J Med",1993,"Young et al.",5,[5,3],[31.01,30.79],41.84,29,21,20,[2,3,2,1,4,2,2,0,1,0,1,1,2,0,0,1],"10.1056/NEJM199304293281704"],[21561347,"FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.","N Engl J Med",2011,"Conroy et al.",2,[1,4,7],[41.72,41.72,37.33],41.72,26,22,17,[0,3,1,3,3,2,3,3,0,0,1,0,1,3,1,0],"10.1056/NEJMoa1011923"],[16760444,"Major congenital malformations after first-trimester exposure to ACE inhibitors.","N Engl J Med",2006,"Cooper et al.",5,[17],[0.0],41.69,36,21,17,[2,5,2,4,1,1,1,1,2,1,1,2,0,1,0,2],"10.1056/NEJMoa055202"],[21449783,"Boceprevir for untreated chronic HCV genotype 1 infection.","N Engl J Med",2011,"Poordad et 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al.",2,[1,3],[38.67,36.42],40.91,30,20,20,[2,4,4,3,4,0,2,1,1,1,0,0,3,2,0,1],"10.1056/NEJMoa0810699"],[27069254,"The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.","Blood",2016,"Arber et al.",6,[10,1],[38.74,31.19],40.9,30,29,14,[0,0,0,0,0,1,5,1,4,5,4,0,6,2,1,1],"10.1182/blood-2016-03-643544"],[17398308,"Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.","Lancet",2007,"Yokoyama et al.",2,[0],[23.01],40.85,27,22,15,[3,1,2,1,2,1,0,1,2,2,3,1,0,1,1,2],"10.1016/S0140-6736(07)60527-3"],[17145251,"Long-term low-molecular-weight heparin versus usual care in proximal-vein thrombosis patients with cancer.","Am J Med",2006,"Hull et al.",2,[0,1],[40.81,27.36],40.81,23,21,17,[3,1,6,2,1,0,0,1,1,1,4,0,0,1,1,0],"10.1016/j.amjmed.2006.02.022"],[7165009,"Toxicity and response criteria of the Eastern Cooperative Oncology Group.","Am J Clin 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al.",2,[0],[39.33],40.43,57,34,11,[2,4,5,4,3,3,3,1,3,4,1,1,2,1,1,1],"10.1056/NEJMoa050496"],[18172173,"Capecitabine and oxaliplatin for advanced esophagogastric cancer.","N Engl J Med",2008,"Cunningham et al.",2,[1,4],[40.42,38.13],40.42,27,22,15,[5,1,3,2,2,1,2,1,3,0,0,2,0,1,1,3],"10.1056/NEJMoa073149"],[22610500,"Benefits and harms of CT screening for lung cancer: a systematic review.","JAMA",2012,"Bach et al.",1,[1,3],[38.28,34.09],40.38,24,21,18,[0,0,4,5,4,3,3,2,0,0,1,0,1,0,1,0],"10.1001/jama.2012.5521"],[16757720,"Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial.","JAMA",2006,"Aoyama et al.",2,[1,5],[40.3,31.55],40.3,27,22,16,[1,3,2,2,1,3,1,4,1,2,0,3,0,2,2,0],"10.1001/jama.295.21.2483"],[36331190,"Empagliflozin in Patients with Chronic Kidney Disease.","N Engl J Med",2023,"Herrington et al.",2,[7,8,0],[25.11,23.95,14.95],40.3,32,28,21,[0,0,0,0,0,0,0,0,0,0,0,0,4,12,7,6],"10.1056/NEJMoa2204233"],[1446890,"Prevalence, classification and natural history of gastric varices: a long-term follow-up study in 568 portal hypertension patients.","Hepatology",1992,"Sarin et al.",5,[4],[40.22],40.22,22,22,16,[0,2,3,0,0,0,2,1,1,2,2,1,1,1,6,0],"10.1002/hep.1840160607"],[10432325,"Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis.","N Engl J Med",1999,"Sort et al.",2,[4,2,8],[37.09,6.77,15.17],40.14,21,21,17,[0,2,1,0,3,2,1,3,1,2,2,0,0,4,0,0],"10.1056/NEJM199908053410603"],[22972103,"Interventions for preventing falls in older people living in the community.","Cochrane Database Syst Rev",2012,"Gillespie et al.",0,[13,7],[24.82,21.14],40.14,23,21,17,[0,0,0,4,2,2,5,4,0,1,1,1,0,0,2,1],"10.1002/14651858.CD007146.pub3"],[19336502,"Effect of clopidogrel added to aspirin in patients with atrial fibrillation.","N Engl J Med",2009,"Connolly et al.",2,[0,5],[37.89,17.76],40.04,43,27,16,[7,5,3,7,1,5,1,1,1,0,0,0,0,2,0,0],"10.1056/NEJMoa0901301"],[26244877,"Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer.","N Engl J Med",2015,"Sweeney et al.",2,[1,8,9],[40.01,40.01,40.01],40.01,31,22,16,[0,0,0,0,0,3,1,4,2,4,4,2,3,3,2,2],"10.1056/NEJMoa1503747"],[19477503,"Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial.","Lancet",2009,"Dennis et al.",2,[0,5],[37.74,12.54],39.98,26,23,15,[3,4,4,2,1,2,1,2,0,0,0,1,0,1,1,3],"10.1016/S0140-6736(09)60941-7"],[11981766,"Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma.","Hepatology",2002,"Lo et al.",2,[1,4],[38.67,38.67],39.89,30,22,16,[0,3,0,1,2,2,3,3,1,1,1,3,2,2,2,0],"10.1053/jhep.2002.33156"],[19846849,"Strict blood-pressure control and progression of renal failure in children.","N Engl J Med",2009,"Wühl et al.",2,[8,0],[23.09,17.76],39.76,24,21,16,[0,0,3,1,0,2,1,0,3,1,2,1,1,2,2,2],"10.1056/NEJMoa0902066"],[8196726,"Cyclosporine in severe ulcerative colitis refractory to steroid therapy.","N Engl J Med",1994,"Lichtiger et al.",2,[4],[39.71],39.71,25,22,14,[4,2,1,1,3,1,3,1,2,2,0,0,2,1,1,1],"10.1056/NEJM199406303302601"],[19389557,"Cardiovascular magnetic resonance in myocarditis: A JACC White Paper.","J Am Coll Cardiol",2009,"Friedrich et al.",4,[0],[38.74],39.67,28,25,13,[1,2,4,1,0,1,2,2,3,4,0,3,1,0,2,0],"10.1016/j.jacc.2009.02.007"],[24744272,"Periprocedural stroke and bleeding complications in patients undergoing catheter ablation of atrial fibrillation with different anticoagulation management: results from the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) randomized trial.","Circulation",2014,"Di Biase et al.",2,[0,5],[39.61,9.02],39.61,25,19,18,[0,1,0,0,1,3,1,7,2,1,0,2,0,2,0,1],"10.1161/CIRCULATIONAHA.113.006426"],[27195814,"Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial.","JAMA",2016,"Williamson et al.",2,[0],[38.69],39.6,32,24,15,[0,0,0,0,0,1,5,2,3,2,3,1,2,4,2,1],"10.1001/jama.2016.7050"],[10675071,"Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators.","Lancet",2000,"",2,[0,7],[25.45,27.45],39.59,33,22,15,[3,4,6,4,1,2,0,0,0,1,2,2,1,1,0,2],""],[15121495,"Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials.","Am J Med",2004,"Taylor et al.",0,[0],[37.16],39.48,53,31,14,[6,7,4,6,3,1,1,2,1,1,0,2,1,1,1,0],"10.1016/j.amjmed.2004.01.009"],[20054046,"Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.","N Engl J Med",2010,"Darouiche et al.",2,[2],[17.85],39.46,30,23,15,[0,1,4,4,2,0,1,4,2,3,0,0,1,1,1,1],"10.1056/NEJMoa0810988"],[37952131,"Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.","N Engl J Med",2023,"Lincoff et al.",2,[7,0],[24.79,18.96],39.43,35,29,24,[0,0,0,0,0,0,0,0,0,0,0,0,0,6,12,11],"10.1056/NEJMoa2307563"],[17075117,"Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group.","J Clin Oncol",2006,"Van Cutsem et al.",2,[1,4],[39.37,37.05],39.37,25,20,15,[5,1,2,2,2,1,1,1,2,1,0,2,0,2,1,1],"10.1200/JCO.2006.06.8429"],[15158627,"Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial.","Lancet",2004,"Andrews et al.",2,[1,5],[39.36,29.12],39.36,23,21,15,[1,2,2,1,0,3,1,2,1,3,1,4,0,1,1,0],"10.1016/S0140-6736(04)16250-8"],[14652541,"The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002.","Gastrointest Endosc",2003,"",6,[4,1],[39.26,31.39],39.26,27,23,16,[0,0,2,0,5,0,1,0,0,3,2,2,0,2,5,1],"10.1016/s0016-5107(03)02159-x"],[12466506,"A comparison of rate control and rhythm control in patients with atrial fibrillation.","N Engl J Med",2002,"Wyse et al.",2,[0],[39.21],39.21,43,28,14,[8,3,5,4,0,3,1,3,0,2,1,1,0,4,0,0],"10.1056/NEJMoa021328"],[16161069,"Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501).","Head Neck",2005,"Bernier et al.",7,[1],[39.2],39.2,26,23,15,[1,0,0,1,1,7,3,1,1,1,0,2,0,1,7,0],"10.1002/hed.20279"],[21593294,"Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes.","Diabetes Care",2011,"Wing et al.",2,[7,0],[36.92,13.73],39.16,27,20,17,[0,0,1,2,1,2,0,2,1,2,0,2,2,4,1,3],"10.2337/dc10-2415"],[18779236,"Continuous glucose monitoring and intensive treatment of type 1 diabetes.","N Engl J Med",2008,"Tamborlane et al.",2,[7],[39.09],39.09,31,24,15,[5,1,3,5,1,2,0,4,3,1,1,0,1,2,0,0],"10.1056/NEJMoa0805017"],[22890223,"Serious infection and mortality in patients with Crohn's disease: more than 5 years of 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Imaging Working Group.","J Clin Oncol",2014,"Barrington et al.",4,[1,10],[34.04,32.31],38.9,27,23,17,[0,0,0,2,4,1,2,2,2,0,4,2,0,3,1,3],"10.1200/JCO.2013.53.5229"],[11547717,"Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.","N Engl J Med",2001,"Kapiteijn et al.",2,[1,4],[38.83,38.83],38.83,28,20,18,[1,1,4,0,4,2,2,3,0,2,0,2,0,0,3,1],"10.1056/NEJMoa010580"],[11547741,"Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction.","N Engl J Med",2001,"Macdonald et al.",2,[1,4],[38.83,36.63],38.83,21,20,16,[5,2,1,2,3,1,0,1,2,0,0,2,0,0,1,1],"10.1056/NEJMoa010187"],[16151544,"Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology.","Can J Gastroenterol",2005,"Silverberg et al.",7,[4],[38.83],38.83,27,22,15,[2,0,3,2,2,0,1,1,2,2,0,0,2,2,6,0],"10.1155/2005/269076"],[26559744,"Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis.","Lancet",2016,"Xie et al.",0,[0],[36.02],38.81,30,23,15,[0,0,0,0,0,1,3,2,5,2,3,1,1,3,2,2],"10.1016/S0140-6736(15)00805-3"],[20206777,"Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial.","Lancet",2010,"Nout et al.",2,[1,9],[38.74,38.74],38.74,28,20,14,[1,2,1,4,0,1,4,1,0,1,2,2,2,0,2,3],"10.1016/S0140-6736(09)62163-2"],[15007110,"Intensive versus moderate lipid lowering with statins after acute coronary syndromes.","N Engl J Med",2004,"Cannon et al.",2,[0],[30.52],38.72,58,29,14,[6,8,3,6,4,2,0,4,3,2,0,1,0,0,1,0],"10.1056/NEJMoa040583"],[15994282,"Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT.","Blood",2005,"Sorror et al.",7,[10,1],[30.41,18.36],38.67,19,19,16,[0,2,1,2,1,1,0,1,2,1,2,0,1,0,4,1],"10.1182/blood-2005-05-2004"],[18191684,"Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial.","Lancet",2008,"Girard et al.",2,[3],[19.74],38.67,27,21,18,[0,0,4,4,1,1,5,1,0,4,1,0,0,2,0,1],"10.1016/S0140-6736(08)60105-1"],[31995683,"Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.","N Engl J Med",2020,"de Koning et al.",2,[1,3],[36.84,35.04],38.65,24,22,23,[0,0,0,0,0,0,0,0,0,0,4,0,4,4,7,3],"10.1056/NEJMoa1911793"],[20430429,"Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial.","Lancet",2010,"Atkin et al.",2,[1,4],[38.64,38.64],38.64,27,21,18,[1,5,6,1,2,3,2,2,0,0,2,0,0,0,0,0],"10.1016/S0140-6736(10)60551-X"],[26712084,"Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial.","Lancet",2016,"Herbst et al.",2,[1,3],[36.55,28.21],38.64,27,21,20,[0,0,0,0,0,0,3,4,5,2,1,1,3,4,0,2],"10.1016/S0140-6736(15)01281-7"],[15382120,"Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleeding.","Hepatology",2004,"Monescillo et al.",2,[4],[38.61],38.61,20,20,16,[0,1,2,0,0,2,2,1,1,3,2,1,0,0,4,1],"10.1002/hep.20386"],[20375404,"Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer.","N Engl J Med",2010,"Valle et al.",2,[1,4],[38.61,38.61],38.61,22,20,16,[1,1,0,1,2,0,1,0,0,1,2,1,4,4,3,0],"10.1056/NEJMoa0908721"],[25882510,"Thrombectomy within 8 hours after symptom onset in ischemic stroke.","N Engl J Med",2015,"Jovin et al.",2,[0,5],[38.61,34.22],38.61,24,22,15,[0,0,0,0,3,2,3,4,5,1,2,0,1,1,1,1],"10.1056/NEJMoa1503780"],[29385358,"Catheter Ablation for Atrial Fibrillation with Heart Failure.","N Engl J Med",2018,"Marrouche et al.",2,[0],[38.54],38.54,29,26,15,[0,0,0,0,0,0,0,3,2,4,3,3,1,7,4,0],"10.1056/NEJMoa1707855"],[19655124,"Intensive glucose control and macrovascular outcomes in type 2 diabetes.","Diabetologia",2009,"Turnbull et al.",0,[7,0],[22.44,24.51],38.45,37,21,18,[3,4,5,3,1,1,1,1,0,2,2,0,1,2,0,0],"10.1007/s00125-009-1470-0"],[25773378,"Efficacy and safety of alirocumab in reducing lipids and cardiovascular events.","N Engl J Med",2015,"Robinson et al.",2,[0,7],[25.38,29.69],38.43,27,22,18,[0,0,0,0,1,4,2,3,5,2,1,2,0,1,0,1],"10.1056/NEJMoa1501031"],[10348829,"New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.","Gastroenterology",1999,"Vasen et al.",7,[1,4,7],[38.41,27.6,19.76],38.41,23,18,19,[0,2,2,2,1,1,2,1,2,2,1,0,0,1,1,1],"10.1016/s0016-5085(99)70510-x"],[21639810,"Ipilimumab plus dacarbazine for previously untreated metastatic melanoma.","N Engl J Med",2011,"Robert et al.",2,[1,14],[38.41,32.32],38.41,22,18,16,[1,2,3,0,2,2,0,1,1,3,3,1,1,0,1,1],"10.1056/NEJMoa1104621"],[33185364,"A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis.","N Engl J Med",2021,"Newsome et al.",2,[4],[28.11],38.38,29,22,22,[0,0,0,0,0,0,0,0,0,0,3,5,1,5,5,4],"10.1056/NEJMoa2028395"],[12167683,"Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis.","N Engl J Med",2002,"Herbrecht et al.",2,[2],[36.2],38.35,20,19,17,[4,0,0,3,0,2,1,2,1,0,1,0,1,1,3,0],"10.1056/NEJMoa020191"],[24004118,"Probability of cancer in pulmonary nodules detected on first screening CT.","N Engl J Med",2013,"McWilliams et al.",3,[3,1],[38.35,34.45],38.35,23,19,17,[0,0,0,1,2,2,3,3,0,1,3,0,1,0,1,4],"10.1056/NEJMoa1214726"],[23323867,"Duodenal infusion of donor feces for recurrent Clostridium difficile.","N Engl J Med",2013,"van Nood et al.",2,[2],[30.25],38.29,21,18,17,[0,0,0,1,2,1,1,3,0,1,3,0,1,3,1,2],"10.1056/NEJMoa1205037"],[15811953,"Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy.","Blood",2005,"Greer et al.",1,[0,9],[27.23,22.09],38.24,23,21,15,[1,7,1,2,0,2,0,3,1,2,2,0,1,1,0,0],"10.1182/blood-2005-02-0626"],[30424892,"SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.","Lancet",2019,"Zelniker et al.",0,[7,0,8],[28.72,21.64,10.83],38.24,28,24,17,[0,0,0,0,0,0,0,0,1,7,4,5,0,4,2,3],"10.1016/S0140-6736(18)32590-X"],[27932229,"Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet",2017,"Bruix et al.",2,[1,4],[38.21,37.56],38.21,26,20,20,[0,0,0,0,0,0,0,2,2,3,3,3,1,7,3,0],"10.1016/S0140-6736(16)32453-9"],[28892457,"Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis.","N Engl J Med",2017,"Saag et al.",2,[13,7],[38.21,35.62],38.21,24,22,17,[0,0,0,0,0,0,0,0,3,3,1,4,3,4,4,1],"10.1056/NEJMoa1708322"],[15642700,"Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS).","Eur Heart J",2005,"Flather et al.",2,[0],[38.16],38.16,32,22,15,[1,3,2,1,4,4,1,2,0,1,1,1,1,1,0,1],"10.1093/eurheartj/ehi115"],[22290281,"Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis.","Br J Surg",2012,"Chabok et al.",2,[4],[32.98],38.12,17,17,17,[0,1,1,2,2,1,2,0,0,1,1,2,0,2,1,1],"10.1002/bjs.8688"],[9718051,"Randomized 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U.S. Carvedilol Heart Failure Study Group.","N Engl J Med",1996,"Packer et al.",2,[0],[37.89],37.89,44,28,11,[2,3,4,1,1,2,1,2,2,3,2,2,2,1,1,1],"10.1056/NEJM199605233342101"],[15625331,"Coronary-artery revascularization before elective major vascular surgery.","N Engl J Med",2004,"McFalls et al.",2,[0],[31.03],37.88,38,24,13,[4,3,2,3,2,1,4,3,0,0,1,1,2,2,0,1],"10.1056/NEJMoa041905"],[15175435,"Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer.","N Engl J Med",2004,"Hurwitz et al.",2,[1,4],[34.89,31.11],37.8,24,19,15,[3,2,2,3,1,1,2,1,3,1,1,0,2,1,0,0],"10.1056/NEJMoa032691"],[25882376,"Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke.","N Engl J Med",2015,"Saver et al.",2,[0,5],[37.78,35.63],37.78,24,22,15,[0,0,0,0,4,2,4,4,4,1,2,0,1,0,1,1],"10.1056/NEJMoa1415061"],[30158069,"Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, 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hip surgery.","N Engl J Med",2011,"Carson et al.",2,[13],[2.69],37.47,20,17,16,[0,2,5,1,1,1,1,1,1,0,1,0,1,1,1,1],"10.1056/NEJMoa1012452"],[21639808,"Improved survival with vemurafenib in melanoma with BRAF V600E mutation.","N Engl J Med",2011,"Chapman et al.",2,[1,14],[37.45,34.57],37.45,22,18,15,[1,2,4,2,1,3,0,1,2,0,1,1,1,1,1,1],"10.1056/NEJMoa1103782"],[21864166,"Azithromycin for prevention of exacerbations of COPD.","N Engl J Med",2011,"Albert et al.",2,[3],[37.45],37.45,21,18,16,[0,1,3,1,1,2,3,1,0,1,1,1,1,1,2,1],"10.1056/NEJMoa1104623"],[31185157,"Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.","N Engl J Med",2019,"Husain et al.",2,[7,0],[28.9,18.86],37.44,29,22,17,[0,0,0,0,0,0,0,0,0,5,3,3,1,6,3,3],"10.1056/NEJMoa1901118"],[21540423,"Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis.","JAMA",2011,"Umpierre et 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al.",2,[7,0],[24.92,17.07],36.85,28,22,16,[0,0,0,0,0,0,0,0,2,6,3,3,1,4,1,5],"10.1016/S0140-6736(18)32261-X"],[22646630,"Preoperative chemoradiotherapy for esophageal or junctional cancer.","N Engl J Med",2012,"van Hagen et al.",2,[1,4],[36.81,36.81],36.81,20,17,17,[0,0,1,1,3,1,1,0,3,1,0,2,1,2,2,1],"10.1056/NEJMoa1112088"],[15972298,"Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis.","Gut",2006,"Ardizzone et al.",2,[4],[36.75],36.75,24,20,14,[3,3,1,1,2,0,3,3,1,2,0,0,2,2,1,0],"10.1136/gut.2005.068809"],[26132939,"A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.","N Engl J Med",2015,"Pi-Sunyer et al.",2,[7],[30.94],36.75,24,20,14,[0,0,0,0,1,1,2,3,1,1,1,3,2,1,2,3],"10.1056/NEJMoa1411892"],[20801500,"Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study.","Lancet",2010,"Swedberg et al.",2,[0],[36.74],36.74,41,23,15,[1,5,1,2,0,5,2,2,2,1,4,0,1,0,1,0],"10.1016/S0140-6736(10)61198-1"],[22077192,"Rivaroxaban in patients with a recent acute coronary syndrome.","N Engl J Med",2012,"Mega et al.",2,[0],[36.74],36.74,34,25,13,[0,4,4,2,5,5,0,4,1,1,1,1,1,0,0,0],"10.1056/NEJMoa1112277"],[24716680,"Spironolactone for heart failure with preserved ejection fraction.","N Engl J Med",2014,"Pitt et al.",2,[0],[34.49],36.74,28,21,14,[0,0,0,0,1,1,3,2,2,1,3,3,1,3,2,1],"10.1056/NEJMoa1313731"],[29425931,"Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis.","Gastroenterology",2018,"Tzartzeva et al.",0,[4,1],[36.71,23.15],36.71,25,20,19,[0,0,0,0,0,0,0,0,1,1,2,4,2,4,2,6],"10.1053/j.gastro.2018.01.064"],[26303131,"Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.","Am J Gastroenterol",2015,"Peyrin-Biroulet et al.",1,[4],[36.66],36.66,25,23,15,[0,0,0,0,0,0,2,3,4,5,3,0,2,2,4,0],"10.1038/ajg.2015.233"],[15152059,"Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure.","N Engl J Med",2004,"Bristow et al.",2,[0],[35.44],36.64,55,33,10,[1,5,5,3,4,3,2,1,3,4,1,1,1,0,0,2],"10.1056/NEJMoa032423"],[23659733,"Pacemaker or defibrillator surgery without interruption of anticoagulation.","N Engl J Med",2013,"Birnie et al.",2,[0],[34.41],36.61,23,20,15,[0,0,1,2,2,2,1,3,2,0,1,2,0,1,0,4],"10.1056/NEJMoa1302946"],[19038879,"Diagnostic performance of coronary angiography by 64-row CT.","N Engl J Med",2008,"Miller et al.",3,[0],[32.9],36.53,28,23,13,[2,4,1,4,0,1,2,3,0,1,0,3,1,1,0,0],"10.1056/NEJMoa0806576"],[21150873,"The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report.","Kidney Int",2011,"Levey et al.",7,[8],[18.89],36.52,19,18,15,[1,1,0,2,1,0,2,3,0,1,1,3,1,1,1,1],"10.1038/ki.2010.483"],[22797452,"Acute respiratory distress syndrome: the Berlin Definition.","JAMA",2012,"Ranieri et al.",4,[3],[25.04],36.5,25,21,20,[0,0,1,1,2,1,3,1,1,6,2,2,1,0,1,0],"10.1001/jama.2012.5669"],[30280640,"Transcatheter Mitral-Valve Repair in Patients with Heart Failure.","N Engl J Med",2018,"Stone et al.",2,[0],[34.48],36.46,33,23,16,[0,0,0,0,0,0,0,0,1,6,8,0,2,4,1,2],"10.1056/NEJMoa1806640"],[20594588,"Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial.","Lancet",2010,"Ismail-Beigi et al.",2,[7,0],[33.25,9.85],36.42,25,18,15,[1,2,3,2,1,2,1,0,2,4,0,1,0,2,0,2],"10.1016/S0140-6736(10)60576-4"],[29129157,"Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.","N Engl J Med",2018,"Nogueira et al.",2,[0,5],[36.37,28.21],36.37,19,19,17,[0,0,0,0,0,0,0,3,4,2,2,0,2,2,2,2],"10.1056/NEJMoa1706442"],[15470214,"Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer.","N Engl J Med",2004,"Petrylak et al.",2,[1,8,9],[36.32,36.32,36.32],36.32,27,18,14,[1,2,4,1,3,2,0,3,1,2,0,1,2,1,2,1],"10.1056/NEJMoa041318"],[20888994,"Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial.","Lancet",2010,"Hallek et al.",2,[1,10],[34.16,34.16],36.31,22,20,15,[3,2,4,1,2,0,2,4,0,0,1,0,0,1,2,0],"10.1016/S0140-6736(10)61381-5"],[14662259,"Does sports activity enhance the risk of sudden death in adolescents and young adults?","J Am Coll Cardiol",2003,"Corrado et al.",5,[0],[33.96],36.24,28,19,14,[2,2,1,1,1,2,2,1,1,1,3,0,0,2,0,2],"10.1016/j.jacc.2003.03.002"],[11346805,"Use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation.","N Engl J Med",2001,"Klein et al.",2,[0],[33.96],36.21,35,22,13,[4,2,1,3,0,3,2,2,1,1,0,2,0,4,1,0],"10.1056/NEJM200105103441901"],[14984936,"A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study.","Gynecol Oncol",2004,"Keys et al.",2,[1,9],[36.21,36.21],36.21,26,20,13,[1,2,1,5,0,1,4,0,0,1,2,1,3,0,1,2],"10.1016/j.ygyno.2003.11.048"],[24679062,"Aspirin in patients undergoing noncardiac surgery.","N Engl J Med",2014,"Devereaux et al.",2,[0],[31.99],36.19,27,19,17,[0,0,0,2,2,0,2,4,1,1,0,4,2,2,0,0],"10.1056/NEJMoa1401105"],[19228612,"Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease.","N Engl J Med",2009,"Serruys et al.",2,[0],[36.17],36.17,58,33,12,[4,6,7,8,5,1,2,2,1,0,1,2,1,2,0,0],"10.1056/NEJMoa0804626"],[27573206,"Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.","N 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The updated Sydney System. 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al.",0,[1,9,7],[36.09,23.08,18.36],36.09,18,17,16,[1,0,1,2,4,1,1,2,1,1,2,0,0,0,2,0],"10.1086/375033"],[17309934,"Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER study.","Circulation",2007,"Canonico et al.",3,[0],[21.86],36.09,20,17,16,[2,1,1,1,2,0,2,2,0,1,1,0,0,4,2,0],"10.1161/CIRCULATIONAHA.106.642280"],[18431116,"STOP questionnaire: a tool to screen patients for obstructive sleep apnea.","Anesthesiology",2008,"Chung et al.",7,[5,3],[22.44,15.17],36.09,19,17,16,[1,0,0,3,1,1,3,1,0,2,0,1,3,1,0,1],"10.1097/ALN.0b013e31816d83e4"],[20656832,"Primary sclerosing cholangitis: meta-analysis of diagnostic performance of MR cholangiopancreatography.","Radiology",2010,"Dave et al.",0,[4],[36.09],36.09,17,17,16,[0,1,2,1,1,0,3,1,2,1,0,1,0,1,0,3],"10.1148/radiol.10091953"],[11172350,"A model to predict survival in patients with end-stage liver disease.","Hepatology",2001,"Kamath et al.",6,[4],[31.64],36.04,21,20,14,[0,2,0,0,2,1,1,3,0,1,1,1,0,2,4,2],"10.1053/jhep.2001.22172"],[18294633,"Risk factors for opportunistic infections in patients with inflammatory bowel disease.","Gastroenterology",2008,"Toruner et al.",5,[4,2],[33.84,5.39],36.04,21,20,14,[4,3,2,1,0,2,1,2,0,0,3,1,1,1,0,0],"10.1053/j.gastro.2008.01.012"],[18927173,"The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.","BMJ",2008,"Belch et al.",2,[7,0],[17.66,36.04],36.04,42,24,13,[4,3,2,4,1,1,3,4,1,2,2,0,0,3,0,3],"10.1136/bmj.a1840"],[22738085,"Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis.","N Engl J Med",2012,"Perner et al.",2,[2],[19.74],36.02,22,20,16,[0,0,6,1,2,5,2,0,0,2,0,1,0,1,0,0],"10.1056/NEJMoa1204242"],[19351941,"Efficacy and safety of exercise training in patients with chronic heart failure: 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force of the American Society for Bone and Mineral Research.","J Bone Miner Res",2014,"Shane et al.",6,[13],[31.48],35.68,20,17,17,[0,0,0,3,1,1,2,0,3,3,0,2,0,1,3,0],"10.1002/jbmr.1998"],[17568028,"Anidulafungin versus fluconazole for invasive candidiasis.","N Engl J Med",2007,"Reboli et al.",2,[2],[33.48],35.63,21,19,15,[4,3,3,1,0,2,2,1,0,0,0,0,1,2,0,1],"10.1056/NEJMoa066906"],[25671797,"Endovascular therapy for ischemic stroke with perfusion-imaging selection.","N Engl J Med",2015,"Campbell et al.",2,[0,5],[35.63,30.56],35.63,23,21,14,[0,0,0,0,3,2,4,4,4,0,2,0,1,1,1,1],"10.1056/NEJMoa1414792"],[21356004,"Saving Mothers' Lives: Reviewing maternal deaths to make motherhood safer: 2006-2008. 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aspirin in the perioperative period: a randomized, controlled clinical trial.","Br J Anaesth",2010,"Oscarsson et al.",2,[0],[31.01],35.49,29,17,16,[1,2,0,1,2,3,1,2,5,0,1,2,1,1,0,0],"10.1093/bja/aeq003"],[34120177,"SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe.","Eur Heart J",2021,"SCORE2 working group and ESC Cardiovascu",7,[0],[27.34],35.46,30,23,19,[0,0,0,0,0,0,0,0,0,0,0,2,1,10,7,5],"10.1093/eurheartj/ehab309"],[24963567,"Cryptogenic stroke and underlying atrial fibrillation.","N Engl J Med",2014,"Sanna et al.",2,[0,5],[35.44,15.45],35.44,28,20,14,[0,0,0,1,1,4,1,2,1,4,2,1,1,4,1,0],"10.1056/NEJMoa1313600"],[12087138,"Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use.","N Engl J Med",2002,"Lai et al.",2,[4],[18.99],35.36,23,17,15,[2,2,3,1,0,1,1,1,2,2,1,1,0,1,1,1],"10.1056/NEJMoa012877"],[19949136,"Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a 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al.",2,[11,0,14],[32.87,30.62,29.12],35.11,20,18,14,[2,0,1,1,1,1,0,0,1,1,2,1,2,2,4,0],"10.1056/NEJMoa0909905"],[17135583,"CD4+ count-guided interruption of antiretroviral treatment.","N Engl J Med",2006,"El-Sadr et al.",2,[2,12,9],[23.76,23.76,21.72],35.1,23,19,14,[3,5,1,4,1,1,1,1,2,0,1,0,1,1,0,0],"10.1056/NEJMoa062360"],[20738765,"A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score.","J Thromb Haemost",2010,"Barbar et al.",5,[0],[29.57],35.08,22,20,19,[0,1,2,1,0,2,0,1,1,5,1,3,1,0,1,2],"10.1111/j.1538-7836.2010.04044.x"],[21041710,"Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study.","J Clin Oncol",2011,"Kocher et al.",2,[1,5],[35.05,26.56],35.05,26,20,15,[0,0,1,3,1,6,0,4,2,0,1,4,0,1,3,0],"10.1200/JCO.2010.30.1655"],[21576658,"Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial.","Circulation",2011,"Eikelboom et al.",2,[0],[35.05],35.05,29,20,15,[0,3,5,4,1,3,1,3,0,1,0,1,0,1,0,0],"10.1161/CIRCULATIONAHA.110.004747"],[21122488,"The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis.","J Crohns Colitis",2010,"Van Assche et al.",4,[4],[34.97],34.97,19,19,16,[1,1,1,4,4,0,5,2,1,0,0,0,0,0,0,0],"10.1016/j.crohns.2009.12.003"],[21477849,"Eosinophilic esophagitis: updated consensus recommendations for children and adults.","J Allergy Clin Immunol",2011,"Liacouras et al.",1,[4,12,10],[34.96,23.28,21.24],34.96,21,19,15,[0,0,2,1,1,2,3,3,0,2,0,0,0,3,2,0],"10.1016/j.jaci.2011.02.040"],[15472670,"Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD.","Gastrointest Endosc",2004,"Daperno et al.",5,[4],[34.94],34.94,19,18,15,[1,1,1,0,2,0,1,2,1,2,0,0,0,3,5,0],"10.1016/s0016-5107(04)01878-4"],[20609967,"Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.","Lancet",2010,"Sarwar et al.",0,[0,7,5],[21.48,21.89,1.0],34.93,23,19,15,[0,1,3,0,0,2,2,3,2,1,2,1,0,2,0,0],"10.1016/S0140-6736(10)60484-9"],[21194870,"Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial.","J Am Coll Cardiol",2011,"Held et al.",7,[0],[34.93],34.93,38,22,13,[3,2,2,2,2,2,1,4,2,0,1,2,0,2,1,0],"10.1016/j.jacc.2010.10.029"],[15622385,"Revision of the CEAP classification for chronic venous disorders: consensus statement.","J Vasc Surg",2004,"Eklöf et al.",4,[0],[32.05],34.9,20,19,13,[3,1,0,2,2,2,1,1,0,2,1,1,1,2,1,0],"10.1016/j.jvs.2004.09.027"],[16287790,"Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study.","Ann Intern Med",2005,"Heit et al.",5,[0,9,3],[32.02,21.89,7.22],34.89,22,18,14,[2,4,2,1,0,2,2,2,2,1,0,0,1,0,1,1],"10.7326/0003-4819-143-10-200511150-00006"],[32343890,"Olaparib for Metastatic Castration-Resistant Prostate Cancer.","N Engl J Med",2020,"de Bono et al.",2,[1,9,8],[34.84,32.67,30.7],34.84,26,22,15,[0,0,0,0,0,0,0,0,0,2,3,6,3,3,7,2],"10.1056/NEJMoa1911440"],[32919526,"Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study.","Lancet Oncol",2020,"Marabelle et al.",3,[1],[34.83],34.83,37,31,13,[0,0,0,0,0,0,0,0,0,0,4,7,7,3,13,3],"10.1016/S1470-2045(20)30445-9"],[11247898,"The risk of colorectal cancer in ulcerative colitis: a meta-analysis.","Gut",2001,"Eaden et al.",0,[4,1],[34.81,16.6],34.81,20,17,16,[1,0,3,2,2,0,0,3,2,1,2,0,1,2,1,0],"10.1136/gut.48.4.526"],[15616203,"Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery.","N Engl J Med",2004,"Sjöström et al.",3,[7],[34.81],34.81,23,17,17,[2,1,3,2,0,1,1,2,1,1,0,2,1,0,0,0],"10.1056/NEJMoa035622"],[21209123,"Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial.","Gut",2011,"Reinisch et al.",2,[4],[34.81],34.81,19,17,16,[0,1,2,1,3,0,2,3,1,1,0,1,2,2,0,0],"10.1136/gut.2010.221127"],[12540794,"Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival.","Hepatology",2003,"Llovet et al.",0,[1,4],[34.79,34.79],34.79,24,17,16,[0,3,2,1,3,1,1,2,1,1,2,1,0,1,2,0],"10.1053/jhep.2003.50047"],[21670242,"Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium.","Circulation",2011,"Mehran et al.",4,[0],[34.79],34.79,24,17,16,[1,2,1,2,1,2,2,1,2,1,2,1,0,0,1,1],"10.1161/CIRCULATIONAHA.110.009449"],[8033378,"Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use.","Clin Exp Dermatol",1994,"Finlay et al.",7,[14],[34.75],34.75,21,21,14,[0,0,0,2,0,2,2,0,2,1,3,0,0,3,3,3],"10.1111/j.1365-2230.1994.tb01167.x"],[25671798,"Randomized assessment of rapid endovascular treatment of ischemic stroke.","N Engl J Med",2015,"Goyal et al.",2,[0,5],[34.75,32.66],34.75,23,21,14,[0,0,0,0,3,2,4,4,4,0,2,0,1,0,1,2],"10.1056/NEJMoa1414905"],[12393647,"Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis.","Blood",2002,"Prandoni et al.",5,[0,1],[34.74,20.4],34.74,21,18,15,[3,3,4,1,1,2,0,0,0,1,2,0,1,0,2,0],"10.1182/blood-2002-01-0108"],[22912386,"Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates.","Circulation",2012,"Siegal et al.",0,[0],[32.58],34.74,19,18,15,[0,0,0,1,0,4,1,2,1,3,0,2,1,2,1,0],"10.1161/CIRCULATIONAHA.112.105221"],[25125077,"Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up.","Hepatology",2015,"Ekstedt et al.",5,[4],[32.58],34.74,24,18,18,[0,0,0,0,1,1,1,0,2,0,2,2,1,4,2,3],"10.1002/hep.27368"],[26409257,"Further Evolution of the ACC/AHA Clinical Practice Guideline Recommendation Classification System: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.","J Am Coll Cardiol",2016,"Halperin et al.",7,[0],[28.98],34.68,53,35,11,[0,0,0,0,0,3,4,0,7,2,5,4,6,7,3,2],"10.1016/j.jacc.2015.09.001"],[22375967,"Shared decision making--pinnacle of patient-centered care.","N Engl J Med",2012,"Barry et al.",7,[16],[6.76],34.67,32,25,12,[0,0,1,2,1,0,1,3,4,1,0,1,1,4,5,1],"10.1056/NEJMp1109283"],[15479938,"Bariatric surgery: a systematic review and meta-analysis.","JAMA",2004,"Buchwald et al.",0,[7],[30.2],34.59,18,17,15,[3,2,0,0,2,0,3,2,1,0,1,1,0,1,1,1],"10.1001/jama.292.14.1724"],[15872200,"Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).","N Engl J Med",2005,"Hampel et al.",7,[1,4,7],[34.59,32.4,18.36],34.59,21,17,18,[1,1,4,1,3,1,0,0,1,2,0,0,0,2,1,1],"10.1056/NEJMoa043146"],[22700854,"Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial.","Circulation",2012,"Healey et al.",2,[0],[32.4],34.59,21,17,17,[0,0,3,1,1,2,1,3,1,1,0,2,0,1,0,2],"10.1161/CIRCULATIONAHA.111.090464"],[26719232,"Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.","Lancet",2016,"James et al.",2,[1,8,9],[34.59,34.0,34.0],34.59,30,21,13,[0,0,0,0,0,1,2,4,2,5,3,3,4,2,2,1],"10.1016/S0140-6736(15)01037-5"],[8950879,"Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. 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al.",2,[2],[34.57],34.57,21,17,13,[1,3,1,3,2,2,0,1,2,0,1,0,1,1,1,1],"10.1182/blood-2010-02-268151"],[35023547,"Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis.","Eur Heart J",2022,"Agarwal et al.",2,[7,8,0],[24.21,19.86,12.39],34.55,24,21,18,[0,0,0,0,0,0,0,0,0,0,0,1,2,7,3,8],"10.1093/eurheartj/ehab777"],[17251531,"Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.","N Engl J Med",2007,"Cornely et al.",2,[2,10],[28.53,15.17],34.51,25,21,12,[5,3,2,2,1,2,0,1,1,0,1,0,0,1,3,1],"10.1056/NEJMoa061094"],[19585548,"High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis.","Hepatology",2009,"Lindor et al.",2,[4],[34.51],34.51,21,18,14,[2,1,1,1,3,0,1,2,1,1,0,1,1,2,3,1],"10.1002/hep.23082"],[20089546,"Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond.","Circulation",2010,"Lloyd-Jones et al.",4,[0],[22.52],34.5,32,29,12,[2,1,7,2,1,2,2,3,2,0,2,2,1,1,1,1],"10.1161/CIRCULATIONAHA.109.192703"],[20647198,"Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis.","N Engl J Med",2010,"Jones et al.",2,[11,0,14],[32.23,30.03,28.49],34.43,20,18,14,[2,0,1,0,1,1,0,0,1,1,2,2,2,2,4,0],"10.1056/NEJMoa0909169"],[24237006,"Targeted temperature management at 33°C versus 36°C after cardiac arrest.","N Engl J Med",2013,"Nielsen et al.",2,[0],[29.38],34.43,21,20,13,[0,0,0,1,5,2,1,2,0,0,1,1,2,2,3,1],"10.1056/NEJMoa1310519"],[28271869,"iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics.","Lancet Oncol",2017,"Seymour et al.",6,[1],[32.39],34.43,27,22,16,[0,0,0,0,0,0,0,5,4,1,1,4,3,0,5,3],"10.1016/S1470-2045(17)30074-8"],[25240821,"Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial.","Lancet Oncol",2014,"Wilke et al.",2,[1,4],[34.37,31.32],34.37,24,19,14,[0,0,0,0,2,2,2,1,3,0,0,3,2,3,3,3],"10.1016/S1470-2045(14)70420-6"],[25975659,"Uninterrupted rivaroxaban vs. uninterrupted vitamin K antagonists for catheter ablation in non-valvular atrial fibrillation.","Eur Heart J",2015,"Cappato et al.",2,[0],[34.33],34.33,26,18,16,[0,1,0,0,2,2,1,7,0,1,0,3,0,4,0,0],"10.1093/eurheartj/ehv177"],[27322798,"Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial.","Ann Intern Med",2016,"Cusi et al.",2,[7,4],[14.06,23.54],34.33,21,18,18,[0,0,0,0,0,0,0,1,1,1,3,4,0,2,3,3],"10.7326/M15-1774"],[16729309,"Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection.","Hepatology",2006,"Sterling et al.",5,[4,2,9],[32.02,11.38,0.0],34.22,23,20,15,[2,1,0,0,1,1,0,0,0,3,1,2,3,4,2,1],"10.1002/hep.21178"],[20573926,"Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR.","N Engl J Med",2010,"Maemondo et al.",2,[1,3],[31.32,30.64],34.22,23,18,17,[2,2,5,1,3,0,1,1,2,1,0,0,2,1,0,0],"10.1056/NEJMoa0909530"],[17582159,"Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis.","J Am Soc Nephrol",2007,"Jayne et al.",2,[0,11],[31.94,26.34],34.18,21,17,14,[1,0,1,0,2,1,0,0,3,1,2,2,1,2,3,1],"10.1681/ASN.2007010090"],[19827166,"Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis.","Hepatology",2010,"Promrat et al.",2,[4],[26.01],34.18,24,17,17,[0,1,2,1,1,2,0,0,1,2,1,2,1,0,2,3],"10.1002/hep.23276"],[20462635,"Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis.","Lancet",2010,"Jun et al.",0,[0],[21.14],34.18,24,17,14,[1,1,3,5,1,1,1,1,1,0,0,2,0,1,0,1],"10.1016/S0140-6736(10)60656-3"],[22001864,"Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review.","Gastroenterology",2012,"Molodecky et al.",1,[4],[34.18],34.18,21,17,14,[0,0,1,2,1,3,1,2,0,3,1,2,2,1,1,0],"10.1053/j.gastro.2011.10.001"],[24512909,"Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis.","Gastroenterology",2014,"Panaccione et al.",2,[4],[34.18],34.18,22,17,15,[0,0,0,1,2,1,2,3,2,2,1,1,2,3,2,0],"10.1053/j.gastro.2013.10.052"],[19502645,"A randomized trial of therapies for type 2 diabetes and coronary artery disease.","N Engl J Med",2009,"Frye et al.",2,[0,7],[31.85,12.23],34.13,43,28,11,[5,3,5,8,2,0,0,1,1,2,1,3,1,3,0,1],"10.1056/NEJMoa0805796"],[23775967,"Randomized controlled trial of entecavir prophylaxis for rituximab-associated hepatitis B virus reactivation in patients with lymphoma and resolved hepatitis B.","J Clin Oncol",2013,"Huang et al.",2,[2,4,1],[22.52,22.52,18.01],34.09,22,18,15,[0,0,2,2,0,3,3,1,1,2,3,0,0,0,3,0],"10.1200/JCO.2012.48.5938"],[26510020,"DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.","N Engl J Med",2015,"Mateo et al.",3,[1,8,9],[34.09,32.35,32.35],34.09,23,18,15,[0,0,0,0,0,2,0,2,2,3,4,2,1,3,4,0],"10.1056/NEJMoa1506859"],[29133605,"Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk).","Circulation",2018,"Bonaca et al.",2,[0,7],[32.12,13.38],34.09,30,22,15,[0,0,0,0,0,0,0,0,6,0,5,3,1,3,2,3],"10.1161/CIRCULATIONAHA.117.032235"],[15028824,"A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.","N Engl J Med",2004,"Neoptolemos et al.",2,[1,4,7],[34.05,34.05,29.02],34.05,18,17,15,[1,3,1,1,2,1,3,0,2,0,0,0,2,1,0,0],"10.1056/NEJMoa032295"],[15289368,"Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients.","Circulation",2004,"Leizorovicz et al.",2,[0,10],[34.05,0.0],34.05,21,19,16,[2,1,5,1,0,1,0,1,0,4,3,1,0,1,0,0],"10.1161/01.CIR.0000138928.83266.24"],[17661241,"A prospective, randomized controlled trial of transjugular intrahepatic portosystemic shunt versus cyanoacrylate injection in the prevention of gastric variceal rebleeding.","Endoscopy",2007,"Lo et al.",2,[4],[34.05],34.05,17,17,15,[0,1,0,1,0,0,1,1,1,3,2,0,0,3,3,1],"10.1055/s-2007-966591"],[12457784,"Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.","Lancet",2002,"Shepherd et al.",2,[0],[28.85],34.04,32,20,13,[2,3,1,4,0,2,1,1,4,1,0,1,0,1,0,2],"10.1016/s0140-6736(02)11600-x"],[30181091,"GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community.","Clin Nutr",2019,"Cederholm et al.",4,[7],[22.17],34.01,22,20,15,[0,0,0,0,0,0,0,0,2,3,4,1,0,3,5,4],"10.1016/j.clnu.2018.08.002"],[19367689,"Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium.","Int J Gynaecol Obstet",2009,"Pecorelli",7,[1,9],[31.68,33.96],33.96,25,20,12,[1,4,3,3,0,1,2,1,2,1,1,1,1,0,4,0],"10.1016/j.ijgo.2009.02.012"],[21345435,"FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age.","Int J Gynaecol Obstet",2011,"Munro et al.",7,[9],[31.72],33.96,21,19,13,[0,3,2,1,1,1,0,2,0,2,0,2,1,1,2,1],"10.1016/j.ijgo.2010.11.011"],[27040324,"Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.","N Engl J Med",2016,"Leon et al.",2,[0],[32.38],33.96,32,20,17,[0,0,0,0,0,0,6,3,3,1,3,2,0,4,0,1],"10.1056/NEJMoa1514616"],[16495695,"A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma.","Ann Surg",2006,"Chen et al.",2,[1,4],[33.9,33.9],33.9,25,16,16,[0,2,1,0,1,2,1,2,1,0,3,2,1,4,0,0],"10.1097/01.sla.0000201480.65519.b8"],[23718166,"Management of antithrombotic therapy in patients undergoing invasive procedures.","N Engl J Med",2013,"Baron et al.",6,[0,1],[18.36,0.0],33.9,17,16,15,[0,0,0,0,2,1,2,1,2,0,2,1,1,3,1,1],"10.1056/NEJMra1206531"],[24881730,"Enzalutamide in metastatic prostate cancer before chemotherapy.","N Engl J Med",2014,"Beer et al.",2,[1,8,9],[33.85,33.85,33.85],33.85,24,16,14,[0,0,0,1,2,2,2,1,1,3,3,1,2,2,3,1],"10.1056/NEJMoa1405095"],[21073365,"Cardiac-resynchronization therapy for mild-to-moderate heart failure.","N Engl J Med",2010,"Tang et al.",2,[0],[33.78],33.78,46,27,10,[2,5,5,3,3,3,1,0,1,4,1,0,2,0,0,0],"10.1056/NEJMoa1009540"],[33359090,"STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD.","Gastroenterology",2021,"Turner et al.",1,[4],[33.77],33.77,27,27,16,[0,0,0,0,0,0,0,0,0,0,0,0,2,8,15,2],"10.1053/j.gastro.2020.12.031"],[31992061,"Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association.","Circulation",2020,"Virani et al.",7,[0,5],[33.76,1.0],33.76,25,24,14,[0,0,0,0,0,0,0,0,0,2,7,5,2,3,3,2],"10.1161/CIR.0000000000000757"],[16647915,"Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality.","Am J Obstet Gynecol",2006,"James et al.",7,[0,9],[27.86,16.74],33.68,19,18,14,[0,3,3,1,0,3,0,3,1,1,0,1,1,0,0,1],"10.1016/j.ajog.2005.11.008"],[18506026,"Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group.","J Clin Oncol",2008,"Pignon et al.",7,[1,3],[33.68,33.68],33.68,19,18,14,[0,1,4,1,4,1,1,0,0,1,0,1,2,0,3,0],"10.1200/JCO.2007.13.9030"],[20172911,"Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria.","Circulation",2010,"Marcus et al.",3,[0,17],[33.68,1.0],33.68,22,20,13,[1,2,0,0,0,1,5,2,2,1,3,1,0,2,0,0],"10.1161/CIRCULATIONAHA.108.840827"],[33031522,"Association of SGLT2 Inhibitors With Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes: A Meta-analysis.","JAMA Cardiol",2021,"McGuire et al.",0,[7,0,8],[24.21,20.03,9.17],33.67,24,21,17,[0,0,0,0,0,0,0,0,0,0,0,2,2,8,4,5],"10.1001/jamacardio.2020.4511"],[35653592,"The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee.","Blood",2022,"Campo et al.",4,[1,10],[31.96,30.27],33.66,25,25,17,[0,0,0,0,0,0,0,0,0,0,0,0,4,8,7,6],"10.1182/blood.2022015851"],[30345884,"Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.","N Engl J Med",2018,"Moore et al.",2,[1,9,7],[33.61,29.7,27.66],33.61,23,21,14,[0,0,0,0,0,0,0,0,3,3,4,2,1,7,2,1],"10.1056/NEJMoa1810858"],[10791524,"Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma.","Lancet",2000,"Creutzberg et al.",2,[1,9],[33.58,33.58],33.58,25,18,13,[1,2,1,4,0,1,4,0,0,1,2,2,2,0,2,1],"10.1016/s0140-6736(00)02139-5"],[16505267,"Incidence of venous thromboembolism and its effect on survival among patients with common cancers.","Arch Intern Med",2006,"Chew et al.",7,[0,1],[29.75,22.09],33.52,17,17,14,[2,3,2,1,1,0,1,0,1,2,1,0,0,2,1,0],"10.1001/archinte.166.4.458"],[19821530,"Acute portal vein thrombosis unrelated to cirrhosis: a prospective multicenter follow-up study.","Hepatology",2010,"Plessier et al.",5,[4,0],[25.69,21.51],33.52,19,17,14,[1,1,0,0,0,2,3,0,0,1,1,2,1,3,2,1],"10.1002/hep.23259"],[23728690,"Pharmacological interventions for smoking cessation: an overview and network meta-analysis.","Cochrane Database Syst Rev",2013,"Cahill et al.",0,[0],[16.43],33.52,21,17,14,[0,0,0,0,2,4,2,1,0,1,1,1,2,1,2,1],"10.1002/14651858.CD009329.pub2"],[28199805,"Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes.","N Engl J Med",2017,"Schauer et al.",2,[7],[31.94],33.52,23,19,15,[0,0,0,0,0,0,0,2,3,3,1,3,1,4,1,2],"10.1056/NEJMoa1600869"],[30280658,"Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC.","N Engl J Med",2018,"Antonia et al.",2,[1,3],[33.49,27.91],33.49,23,20,16,[0,0,0,0,0,0,0,0,0,4,4,3,4,1,5,1],"10.1056/NEJMoa1809697"],[25629739,"Less-tight versus tight control of hypertension in pregnancy.","N Engl J Med",2015,"Magee et al.",2,[9,0],[21.7,24.48],33.48,22,17,16,[0,0,0,0,0,2,0,3,3,2,0,2,0,2,3,2],"10.1056/NEJMoa1404595"],[26350171,"Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research.","J Bone Miner Res",2016,"Adler et al.",6,[13,7],[31.44,29.4],33.48,20,17,16,[0,0,0,0,0,1,3,0,4,2,0,3,0,2,2,2],"10.1002/jbmr.2708"],[30516102,"Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.","N Engl J Med",2019,"von Minckwitz et al.",2,[1],[33.48],33.48,20,17,16,[0,0,0,0,0,0,0,0,1,2,4,2,1,5,2,2],"10.1056/NEJMoa1814017"],[21664710,"Reduced dose radiotherapy for local control in non-Hodgkin lymphoma: a randomised phase III trial.","Radiother Oncol",2011,"Lowry et al.",2,[1,10],[33.35,32.05],33.35,20,19,12,[0,1,1,1,3,3,0,1,1,2,1,1,0,2,2,1],"10.1016/j.radonc.2011.05.013"],[19736261,"Dramatic increase in venous thromboembolism in children's hospitals in the United States from 2001 to 2007.","Pediatrics",2009,"Raffini et al.",5,[0],[25.52],33.33,21,19,14,[1,2,0,0,1,1,2,2,0,2,1,1,0,3,1,3],"10.1542/peds.2009-0768"],[27663604,"Transjugular Intrahepatic Portosystemic Shunts With Covered Stents Increase Transplant-Free Survival of Patients With Cirrhosis and Recurrent Ascites.","Gastroenterology",2017,"Bureau et al.",2,[4],[33.32],33.32,19,19,14,[0,0,0,0,0,0,1,3,2,1,3,1,0,4,3,1],"10.1053/j.gastro.2016.09.016"],[14693982,"XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients.","Diabetes Care",2004,"Torgerson et al.",2,[7],[31.11],33.31,22,17,17,[2,0,1,0,3,1,0,3,1,2,0,2,1,2,1,0],"10.2337/diacare.27.1.155"],[18728267,"Benefits and risks of tight glucose control in critically ill adults: a meta-analysis.","JAMA",2008,"Wiener et al.",0,[7,2],[18.57,5.08],33.31,29,17,16,[7,2,5,1,1,0,1,2,0,1,1,1,0,0,2,0],"10.1001/jama.300.8.933"],[18809606,"Feasibility of screening for Lynch syndrome among patients with colorectal cancer.","J Clin Oncol",2008,"Hampel et al.",7,[1,4,17],[33.31,26.71,18.36],33.31,21,17,17,[2,1,3,1,3,1,0,1,3,1,0,1,0,1,0,0],"10.1200/JCO.2008.17.5950"],[21328309,"Adverse effects of biologics: a network meta-analysis and Cochrane overview.","Cochrane Database Syst Rev",2011,"Singh et al.",0,[11],[15.77],33.31,18,17,14,[1,1,3,2,0,0,2,1,2,2,2,1,0,1,0,0],"10.1002/14651858.CD008794.pub2"],[23063316,"Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial.","Lancet",2012,"Laharie et al.",2,[4],[33.31],33.31,20,17,15,[0,0,1,0,0,0,2,4,2,1,1,2,2,1,3,1],"10.1016/S0140-6736(12)61084-8"],[23215555,"Chromosomal microarray versus karyotyping for prenatal diagnosis.","N Engl J Med",2012,"Wapner et al.",3,[17],[21.29],33.31,21,17,14,[0,0,1,1,3,3,2,0,0,1,2,0,1,3,1,1],"10.1056/NEJMoa1203382"],[8634613,"Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures.","BMJ",1996,"Marshall et al.",0,[13,7],[31.7,29.5],33.25,20,16,14,[2,1,1,1,1,2,4,0,3,1,0,1,0,1,2,0],"10.1136/bmj.312.7041.1254"],[11306229,"Current methods of the US Preventive Services Task Force: a review of the process.","Am J Prev Med",2001,"Harris et al.",7,[],[],33.25,19,18,14,[1,1,1,4,1,1,1,0,2,2,1,0,0,2,0,2],"10.1016/s0749-3797(01)00261-6"],[18537184,"Simplified criteria for the diagnosis of autoimmune 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with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial.","J Clin Oncol",2009,"André et al.",2,[1,4],[33.18,33.18],33.18,25,20,12,[3,3,3,1,0,0,2,1,1,3,2,2,0,2,1,0],"10.1200/JCO.2008.20.6771"],[16790698,"Cyclophosphamide versus placebo in scleroderma lung disease.","N Engl J Med",2006,"Tashkin et al.",2,[11,3,14],[21.7,18.36,15.78],33.16,20,16,16,[0,3,1,0,1,0,2,1,0,0,0,1,1,5,1,2],"10.1056/NEJMoa055120"],[19158356,"New equations to estimate GFR in children with CKD.","J Am Soc Nephrol",2009,"Schwartz et al.",5,[8],[14.44],33.16,16,16,15,[1,0,2,3,0,2,1,1,1,0,1,0,0,1,3,0],"10.1681/ASN.2008030287"],[23474284,"Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.","Gastroenterology",2013,"Moreau et al.",5,[4],[33.16],33.16,22,22,12,[0,0,0,0,1,2,0,2,1,2,2,0,4,4,4,0],"10.1053/j.gastro.2013.02.042"],[23935011,"Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study.","Circulation",2013,"Sarode et al.",2,[0],[23.08],33.16,21,18,14,[0,0,0,0,2,1,2,1,3,1,0,3,1,4,1,0],"10.1161/CIRCULATIONAHA.113.002283"],[15313740,"Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial.","Ann Intern Med",2004,"Prandoni et al.",2,[0],[33.13],33.13,21,18,15,[2,4,2,3,0,3,0,0,0,1,4,1,0,0,0,0],"10.7326/0003-4819-141-4-200408170-00004"],[23450531,"Colloids versus crystalloids for fluid resuscitation in critically ill patients.","Cochrane Database Syst Rev",2013,"Perel et al.",0,[4],[15.17],33.13,18,18,15,[0,0,0,0,4,4,3,0,1,2,0,1,1,0,2,0],"10.1002/14651858.CD000567.pub6"],[25981908,"High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure.","N Engl J Med",2015,"Frat et 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The Bogalusa Heart Study.","N Engl J Med",1998,"Berenson et al.",7,[0],[24.48],33.11,27,23,14,[6,0,3,2,2,0,0,2,0,1,0,3,1,2,0,1],"10.1056/NEJM199806043382302"],[19465231,"Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials.","Lancet",2009,"Ray et al.",0,[0,7],[23.9,15.95],33.11,31,19,16,[2,2,5,2,0,1,2,2,1,0,1,0,0,1,0,0],"10.1016/S0140-6736(09)60697-8"],[12135033,"Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease.","Am J Gastroenterol",2002,"McFarland et al.",2,[2,4],[24.62,12.65],33.04,18,16,14,[2,0,1,1,1,0,0,3,0,1,1,1,1,2,1,2],"10.1111/j.1572-0241.2002.05839.x"],[19299006,"Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies.","Lancet",2009,"Whitlock et al.",5,[0,5,3],[10.87,1.35,0.0],33.04,27,16,16,[3,1,2,2,1,1,0,1,1,1,0,2,0,1,2,0],"10.1016/S0140-6736(09)60318-4"],[25131978,"Blood pressure-lowering treatment based on cardiovascular risk: a meta-analysis of individual patient data.","Lancet",2014,"Blood Pressure Lowering Treatment Triali",0,[0],[27.09],33.02,24,17,15,[0,0,0,0,1,5,1,2,3,1,1,0,0,0,2,3],"10.1016/S0140-6736(14)61212-5"],[28434648,"Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial.","Lancet",2017,"El-Khoueiry et al.",3,[1,4],[33.02,28.82],33.02,22,17,17,[0,0,0,0,0,0,1,2,2,4,4,2,1,3,2,0],"10.1016/S0140-6736(17)31046-2"],[30312372,"Sarcopenia: revised European consensus on definition and diagnosis.","Age Ageing",2019,"Cruz-Jentoft et al.",4,[5],[4.65],33.02,20,18,17,[0,0,0,0,0,0,0,0,0,0,4,2,2,3,5,3],"10.1093/ageing/afy169"],[29105841,"Vertebral Fractures After Discontinuation of Denosumab: A Post Hoc Analysis of the Randomized Placebo-Controlled FREEDOM Trial and Its Extension.","J Bone Miner Res",2018,"Cummings et al.",2,[13],[31.04],33.01,21,18,16,[0,0,0,0,0,0,0,0,4,4,0,3,2,4,1,1],"10.1002/jbmr.3337"],[17599306,"A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity.","Clin Infect Dis",2007,"Zar et al.",2,[2,4],[22.44,10.83],32.98,15,15,15,[1,0,1,1,1,0,0,3,1,1,3,1,0,1,1,0],"10.1086/519265"],[19155235,"The 10-year follow-up data of the Euro-Lupus Nephritis Trial comparing low-dose and high-dose intravenous cyclophosphamide.","Ann Rheum Dis",2010,"Houssiau et al.",2,[11,8],[30.12,16.6],32.98,20,17,15,[0,4,3,1,1,0,1,1,2,0,1,0,1,2,0,2],"10.1136/ard.2008.102533"],[20673995,"Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet",2010,"Greenway et al.",2,[7],[30.74],32.98,23,19,13,[0,1,1,0,2,1,3,2,1,1,0,3,0,1,2,3],"10.1016/S0140-6736(10)60888-4"],[10438259,"Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group.","N Engl J Med",1999,"Rubins et al.",2,[7,0,17],[30.93,22.9,0.0],32.96,41,23,14,[5,5,3,4,2,2,1,1,2,0,1,0,0,0,0,1],"10.1056/NEJM199908053410604"],[24094768,"Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial.","Lancet",2014,"Fuchs et al.",2,[1,4],[32.93,27.62],32.93,22,18,13,[0,0,0,1,2,3,3,1,2,0,0,2,1,1,3,3],"10.1016/S0140-6736(13)61719-5"],[34449181,"Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes.","N Engl J Med",2021,"Pitt et al.",2,[7,0,8],[22.4,15.94,15.19],32.92,24,20,17,[0,0,0,0,0,0,0,0,0,0,0,2,3,6,4,6],"10.1056/NEJMoa2110956"],[18358928,"Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial.","Lancet",2008,"Nordlinger et al.",2,[1,4],[32.87,32.87],32.87,21,17,13,[2,2,4,3,1,1,2,0,1,0,1,1,1,0,1,0],"10.1016/S0140-6736(08)60455-9"],[22595799,"Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.","Lancet",2012,"van der Graaf et al.",2,[1],[32.87],32.87,22,17,13,[0,1,1,1,2,2,1,1,0,0,3,1,3,1,4,0],"10.1016/S0140-6736(12)60651-5"],[24963045,"Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials.","Blood",2014,"van Es et al.",0,[0],[26.17],32.86,22,18,14,[0,0,0,0,1,3,0,2,1,3,4,0,0,1,4,1],"10.1182/blood-2014-04-571232"],[9411221,"A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias.","N Engl J Med",1997,"Antiarrhythmics versus Implantable Defib",2,[0],[32.27],32.83,43,29,9,[1,2,5,4,1,4,1,1,1,1,1,2,3,3,1,0],"10.1056/NEJM199711273372202"],[19723701,"Cardiac-resynchronization therapy for the prevention of heart-failure events.","N Engl J Med",2009,"Moss et al.",2,[0],[31.75],32.81,49,27,9,[1,5,4,3,3,3,0,0,1,5,1,1,2,2,0,1],"10.1056/NEJMoa0906431"],[24131140,"Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine.","N Engl J Med",2013,"Von Hoff et al.",2,[1,4,7],[32.79,32.79,30.64],32.79,20,17,14,[0,0,1,2,2,2,3,2,0,0,1,0,1,3,1,0],"10.1056/NEJMoa1304369"],[25754617,"Hormone therapy for preventing cardiovascular disease in post-menopausal women.","Cochrane Database Syst Rev",2015,"Boardman et al.",0,[0],[22.74],32.79,25,19,15,[0,0,0,0,1,0,1,2,0,1,6,1,1,4,1,2],"10.1002/14651858.CD002229.pub4"],[23433739,"Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre, randomised, phase 3 non-inferiority trial.","Lancet",2013,"Rummel et al.",2,[1,10],[32.76,32.76],32.76,26,21,11,[0,0,2,5,0,1,2,2,0,2,1,3,1,3,2,2],"10.1016/S0140-6736(12)61763-2"],[20587587,"Effects of medical therapies on retinopathy progression in type 2 diabetes.","N Engl J Med",2010,"Chew et al.",2,[7,0,15],[32.72,12.9,7.58],32.72,25,18,13,[1,2,4,3,2,2,2,0,2,1,0,2,0,1,0,0],"10.1056/NEJMoa1001288"],[13678871,"Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial.","Lancet",2003,"Yusuf et al.",2,[0],[32.69],32.69,31,20,11,[0,1,2,1,2,1,3,2,2,1,1,2,1,2,1,1],"10.1016/S0140-6736(03)14285-7"],[12057549,"Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial.","Lancet",2002,"Altman et al.",2,[9],[28.28],32.65,19,17,13,[1,0,0,1,1,3,1,1,2,2,0,2,2,1,0,1],"10.1016/s0140-6736(02)08778-0"],[12466507,"A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation.","N Engl J Med",2002,"Van Gelder et al.",2,[0],[32.65],32.65,34,21,11,[3,1,2,5,0,4,1,2,0,1,0,1,1,4,0,1],"10.1056/NEJMoa021375"],[21047223,"Safety of recombinant activated factor VII in randomized clinical trials.","N Engl J Med",2010,"Levi et al.",7,[0],[18.33],32.65,17,17,13,[1,1,3,1,2,0,2,2,1,1,0,1,1,0,1,0],"10.1056/NEJMoa1006221"],[21200007,"Dabigatran versus warfarin in patients with atrial fibrillation: an analysis of patients undergoing cardioversion.","Circulation",2011,"Nagarakanti et al.",2,[0,5],[32.65,13.81],32.65,26,17,13,[1,2,2,2,1,3,2,3,1,1,0,1,0,1,0,0],"10.1161/CIRCULATIONAHA.110.977546"],[25601341,"Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study.","Lancet Oncol",2015,"Ryan et al.",2,[1,8,9],[32.65,32.65,32.65],32.65,23,17,13,[0,0,0,0,2,2,1,2,1,2,1,2,3,2,4,1],"10.1016/S1470-2045(14)71205-7"],[23964933,"Vedolizumab as induction and maintenance therapy for Crohn's disease.","N Engl J Med",2013,"Sandborn et al.",2,[4],[32.64],32.64,20,18,15,[0,0,0,0,0,0,4,1,2,3,1,0,1,4,4,0],"10.1056/NEJMoa1215739"],[10930365,"Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial.","Gastroenterology",2000,"Gionchetti et al.",2,[4],[32.61],32.61,19,16,14,[3,1,1,1,1,0,1,2,1,3,0,0,2,3,0,0],"10.1053/gast.2000.9370"],[15163774,"A comparison of albumin and saline for fluid resuscitation in the intensive care unit.","N Engl J Med",2004,"Finfer et al.",2,[2],[15.19],32.61,18,16,14,[1,2,2,1,2,2,0,1,1,0,0,1,0,3,1,0],"10.1056/NEJMoa040232"],[15163775,"Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism.","N Engl J Med",2004,"Pengo et al.",7,[0,3],[32.61,20.63],32.61,18,16,14,[3,1,3,1,2,2,0,1,1,1,1,1,0,0,0,0],"10.1056/NEJMoa032274"],[16052573,"Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody-associated vasculitis.","Arthritis Rheum",2005,"De Groot et al.",2,[0,11],[27.6,27.6],32.61,18,16,14,[1,1,0,0,1,1,0,0,1,1,2,2,2,2,3,0],"10.1002/art.21142"],[20833738,"Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial.","Ann Rheum Dis",2010,"Houssiau et al.",2,[11,8],[29.75,15.17],32.61,18,16,15,[0,3,3,1,1,0,0,1,2,0,1,0,1,2,1,1],"10.1136/ard.2010.131995"],[20940381,"Transfusion requirements after cardiac surgery: the TRACS randomized 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The National Polyp Study Workgroup.","N Engl J Med",1993,"Winawer et al.",5,[1,4],[29.69,29.69],31.79,22,17,15,[2,3,3,0,2,0,1,1,0,2,2,0,0,2,0,0],"10.1056/NEJM199312303292701"],[18612117,"Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis.","JAMA",2008,"Fowkes et al.",0,[0],[31.77],31.77,39,20,14,[2,4,3,2,1,2,3,1,0,1,0,0,0,2,0,1],"10.1001/jama.300.2.197"],[18003959,"Teriparatide or alendronate in glucocorticoid-induced osteoporosis.","N Engl J Med",2007,"Saag et al.",2,[7,13],[31.7,31.7],31.7,17,15,14,[2,2,2,2,1,0,1,0,2,1,0,0,1,1,0,1],"10.1056/NEJMoa071408"],[19801505,"Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major.","Circulation",2009,"Kirk et al.",3,[0,10,17],[7.47,16.79,15.78],31.7,17,15,14,[0,0,3,1,1,0,0,0,1,3,1,2,1,1,2,1],"10.1161/CIRCULATIONAHA.109.874487"],[20054045,"Preventing surgical-site infections in nasal carriers of Staphylococcus aureus.","N Engl J Med",2010,"Bode et al.",2,[2],[23.08],31.7,17,15,14,[2,0,1,3,1,0,1,1,1,1,0,1,0,2,0,1],"10.1056/NEJMoa0808939"],[22634125,"A randomized controlled trial of radiofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma.","J Hepatol",2012,"Feng et al.",2,[1,4],[29.5,29.5],31.7,24,15,15,[0,0,1,0,1,2,1,2,1,0,4,2,2,3,1,0],"10.1016/j.jhep.2012.05.007"],[4007423,"Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy.","Gastroenterology",1985,"Haggitt et al.",5,[1,4],[31.69,31.69],31.69,19,16,15,[0,1,2,0,3,0,1,1,0,3,1,1,0,0,3,1],"10.1016/0016-5085(85)90333-6"],[16481635,"Calcium plus vitamin D supplementation and the risk of fractures.","N Engl J Med",2006,"Jackson et al.",2,[13],[20.63],31.68,20,17,12,[1,3,3,0,0,2,2,1,1,1,1,1,1,1,1,0],"10.1056/NEJMoa055218"],[20587585,"Effectiveness of sensor-augmented insulin-pump therapy in type 1 diabetes.","N Engl J Med",2010,"Bergenstal et al.",2,[7],[31.64],31.64,21,20,11,[1,1,3,2,0,3,0,4,1,0,1,0,1,3,0,1],"10.1056/NEJMoa1002853"],[1900101,"Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.","N Engl J Med",1991,"Echt et al.",2,[0],[31.59],31.59,38,21,10,[1,2,1,3,2,4,0,2,1,3,1,1,2,2,1,0],"10.1056/NEJM199103213241201"],[17215529,"Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.","N Engl J Med",2007,"Motzer et al.",2,[1,8],[30.95,26.24],31.58,25,16,12,[2,4,1,2,2,2,1,3,1,1,2,1,1,1,0,1],"10.1056/NEJMoa065044"],[9164216,"Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups.","J Clin Oncol",1997,"Bartelink et al.",2,[1,4],[31.56,29.28],31.56,21,15,13,[1,1,1,3,0,1,2,2,0,0,2,1,1,1,2,1],"10.1200/JCO.1997.15.5.2040"],[16131373,"Paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review.","Transfusion",2005,"Segal et al.",6,[10,0],[12.16,11.38],31.56,16,15,13,[1,1,1,2,0,0,1,2,1,1,1,0,1,1,1,1],"10.1111/j.1537-2995.2005.00546.x"],[18460553,"Long-term results and risk factor analysis for recurrence after curative endoscopic therapy in 349 patients with high-grade intraepithelial neoplasia and mucosal adenocarcinoma in Barrett's oesophagus.","Gut",2008,"Pech et al.",7,[1,4],[29.28,31.56],31.56,20,19,11,[3,1,1,1,2,2,0,1,0,1,1,1,1,3,2,0],"10.1136/gut.2007.142539"],[20197530,"Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial.","JAMA",2010,"Fowkes et al.",2,[0,5],[31.56,2.69],31.56,42,23,12,[5,5,1,1,1,2,3,3,1,1,1,0,0,3,0,1],"10.1001/jama.2010.221"],[19269895,"Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.","Lancet Oncol",2009,"Stupp et al.",2,[1,5],[29.38,23.59],31.53,21,17,13,[1,1,1,3,1,3,3,0,0,0,1,3,0,0,3,0],"10.1016/S1470-2045(09)70025-7"],[26842679,"Antenatal Betamethasone for Women at Risk for Late Preterm Delivery.","N Engl J Med",2016,"Gyamfi-Bannerman et al.",2,[17,3],[9.86,5.41],31.53,28,20,12,[0,0,0,0,0,4,4,2,6,2,2,3,3,0,0,1],"10.1056/NEJMoa1516783"],[10075613,"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. 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al.",2,[1,7,9],[30.41,25.45,25.45],30.41,17,15,13,[4,1,2,1,1,1,0,0,3,0,1,1,0,1,1,0],"10.1056/NEJMoa052985"],[17876019,"Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial.","Ann Intern Med",2007,"Sigal et al.",2,[7],[27.6],30.41,20,15,14,[3,0,2,1,3,2,0,1,1,1,0,3,1,1,0,0],"10.7326/0003-4819-147-6-200709180-00005"],[19726226,"Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: a randomised, placebo-controlled, double-blind study.","Lancet Oncol",2009,"Agnelli et al.",2,[1,0],[30.41,26.05],30.41,17,15,13,[2,1,4,2,1,1,0,0,1,1,1,0,1,2,0,0],"10.1016/S1470-2045(09)70232-3"],[19897665,"Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials.","BMJ",2009,"De Berardis et 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al.",2,[1],[30.08],30.08,18,14,13,[2,2,1,1,2,4,0,1,1,0,1,0,1,1,0,1],"10.1056/NEJMoa041588"],[19762075,"Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial.","Lancet",2009,"Peek et al.",2,[3],[19.76],30.08,18,14,13,[1,1,1,2,0,0,2,0,1,1,0,2,1,1,1,1],"10.1016/S0140-6736(09)61069-2"],[22285168,"Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial.","Lancet Oncol",2012,"Rosell et al.",2,[1,3],[27.84,27.84],30.08,23,14,16,[0,1,3,2,4,1,1,1,2,1,0,0,2,2,0,1],"10.1016/S1470-2045(11)70393-X"],[29437910,"Modern diagnosis of GERD: the Lyon Consensus.","Gut",2018,"Gyawali et al.",6,[4],[26.13],30.07,19,17,15,[0,0,0,0,0,0,0,0,1,2,0,3,3,5,3,1],"10.1136/gutjnl-2017-314722"],[24084921,"Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials.","JAMA",2013,"Manson et al.",2,[0,1],[16.6,15.17],30.06,21,17,12,[0,0,0,1,1,0,4,1,1,0,4,3,0,1,2,1],"10.1001/jama.2013.278040"],[10403727,"Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification.","Gut",1999,"Lundell et al.",7,[4],[30.05],30.05,16,16,14,[0,3,0,1,1,2,2,0,0,0,0,1,0,2,4,0],"10.1136/gut.45.2.172"],[15337732,"Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial.","JAMA",2004,"de Lemos et al.",2,[0],[24.17],30.05,40,20,13,[3,5,3,6,1,2,1,0,2,0,0,1,0,0,2,0],"10.1001/jama.292.11.1307"],[24315521,"Compression stockings to prevent post-thrombotic syndrome: a randomised placebo-controlled trial.","Lancet",2014,"Kahn et al.",2,[0],[30.05],30.05,20,16,14,[0,0,0,3,0,3,1,0,1,2,6,1,0,1,0,0],"10.1016/S0140-6736(13)61902-9"],[22204724,"Incorporation of bevacizumab in the primary treatment of ovarian cancer.","N Engl J Med",2011,"Burger et al.",2,[1,9,7],[30.02,30.02,27.24],30.02,21,17,11,[0,1,1,1,1,0,1,0,5,1,4,1,1,3,1,0],"10.1056/NEJMoa1104390"],[16705109,"Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials.","JAMA",2006,"Bongartz et al.",0,[11],[16.99],30.01,18,17,15,[6,3,0,0,2,2,3,0,1,0,0,0,0,0,0,0],"10.1001/jama.295.19.2275"],[31422062,"Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.","Lancet Diabetes Endocrinol",2019,"Kristensen et al.",0,[7,0,8],[15.93,15.95,8.47],30.01,25,19,16,[0,0,0,0,0,0,0,0,0,2,2,2,3,7,0,3],"10.1016/S2213-8587(19)30249-9"],[31851799,"Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer.","N Engl J Med",2019,"Ray-Coquard et al.",2,[1,9,7],[30.01,27.0,24.32],30.01,20,19,14,[0,0,0,0,0,0,0,0,0,3,3,0,2,7,2,3],"10.1056/NEJMoa1911361"],[35732831,"The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms.","Leukemia",2022,"Khoury et al.",6,[10,1],[27.5,17.18],29.9,24,24,14,[0,0,0,0,0,0,0,0,0,0,0,0,7,9,3,5],"10.1038/s41375-022-01613-1"],[6231933,"Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria.","Arthritis Rheum",1984,"van der Linden et al.",7,[11,13],[24.97,22.93],29.89,21,16,14,[1,1,1,2,4,1,3,0,4,0,3,0,0,0,0,0],"10.1002/art.1780270401"],[18295023,"Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial.","Lancet",2008,"D'Haens et al.",2,[4],[29.89],29.89,16,16,13,[2,1,3,2,0,0,1,0,2,0,1,0,0,2,2,0],"10.1016/S0140-6736(08)60304-9"],[19801201,"Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial.","Lancet Oncol",2009,"Chang et al.",2,[1,5,13],[29.89,23.78,0.0],29.89,18,18,12,[0,1,2,3,0,2,1,2,0,0,0,3,0,2,2,0],"10.1016/S1470-2045(09)70263-3"],[25644760,"Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial.","Hepatology",2015,"Cavallin et al.",2,[4,8],[28.21,15.45],29.89,19,18,12,[0,0,0,0,0,1,0,3,2,1,3,1,1,5,2,0],"10.1002/hep.27709"],[18325358,"The diagnostic accuracy of CT and MRI in the staging of pelvic lymph nodes in patients with prostate cancer: a meta-analysis.","Clin Radiol",2008,"Hövels et al.",0,[1,8,9],[29.87,27.11,25.92],29.87,19,16,11,[1,2,2,1,1,1,2,1,0,1,1,1,1,3,1,0],"10.1016/j.crad.2007.05.022"],[22093187,"Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial.","Lancet",2012,"Smith et al.",2,[1,8,9],[27.55,24.72,24.72],29.83,21,16,11,[0,3,3,2,1,1,1,1,0,2,1,1,2,2,1,0],"10.1016/S0140-6736(11)61226-9"],[10733541,"A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts.","Hepatology",2000,"Malinchoc et al.",7,[4],[29.82],29.82,19,18,12,[0,0,1,1,1,1,0,3,0,1,2,1,0,4,2,1],"10.1053/he.2000.5852"],[16079372,"Adherence to medication.","N Engl J Med",2005,"Osterberg et al.",6,[0,6,12],[6.32,1.0,1.0],29.82,23,16,14,[1,2,1,2,1,3,0,2,0,1,1,0,0,2,1,0],"10.1056/NEJMra050100"],[25891173,"Pembrolizumab versus Ipilimumab in Advanced Melanoma.","N Engl J Med",2015,"Robert et al.",2,[1,14],[29.82,24.51],29.82,20,16,12,[0,0,0,0,1,1,1,2,2,2,3,2,2,0,2,2],"10.1056/NEJMoa1503093"],[20101745,"Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease.","Hepatology",2010,"Wong et al.",5,[4],[27.03],29.81,19,17,11,[1,1,2,2,1,1,1,1,0,0,3,1,1,3,0,0],"10.1002/hep.23312"],[15755765,"Intensive lipid lowering with atorvastatin in patients with stable coronary disease.","N Engl J Med",2005,"LaRosa et al.",2,[0],[22.5],29.79,54,27,10,[4,5,2,6,3,2,1,2,3,1,0,2,1,0,1,1],"10.1056/NEJMoa050461"],[30883055,"Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation.","N Engl J Med",2019,"Lopes et al.",2,[0],[27.73],29.77,26,20,12,[0,0,0,0,0,0,0,0,1,2,2,4,2,9,1,1],"10.1056/NEJMoa1817083"],[1991946,"The timed \"Up 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al.",7,[4,1],[29.75,25.82],29.75,23,15,15,[0,3,0,0,2,2,1,0,1,0,2,2,1,3,0,1],"10.1053/jhep.2001.24563"],[11442521,"Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery.","Br J Surg",2001,"Mismetti et al.",0,[0],[26.92],29.75,17,15,13,[1,2,5,0,0,1,1,1,1,0,2,1,0,0,0,1],"10.1046/j.0007-1323.2001.01800.x"],[12103287,"Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial.","Lancet",2002,"O'Sullivan et al.",2,[1],[29.75],29.75,17,15,13,[1,1,1,1,2,3,0,1,0,0,2,0,0,0,3,2],"10.1016/S0140-6736(02)09292-9"],[19934295,"Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria.","Clin Cancer Res",2009,"Wolchok et al.",2,[1,14],[29.75,6.77],29.75,19,17,13,[0,0,1,0,2,1,2,4,3,0,2,1,2,0,0,1],"10.1158/1078-0432.CCR-09-1624"],[20083827,"Opioid prescriptions for chronic pain and overdose: a cohort study.","Ann Intern Med",2010,"Dunn et al.",5,[6],[22.72],29.75,19,15,13,[1,1,2,3,0,2,3,1,0,0,1,2,1,0,0,0],"10.7326/0003-4819-152-2-201001190-00006"],[22087680,"Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis.","N Engl J Med",2011,"Dooley et al.",2,[11,8],[26.92,15.17],29.75,17,15,14,[0,3,3,1,1,0,0,1,2,0,1,0,1,2,0,1],"10.1056/NEJMoa1014460"],[23735746,"Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis.","Gastroenterology",2014,"Sandborn et al.",2,[4],[29.75],29.75,17,15,14,[0,0,0,0,2,0,3,2,1,1,1,1,2,2,2,0],"10.1053/j.gastro.2013.05.048"],[20209604,"The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis.","Hepatology",2010,"Ascha et al.",5,[4,1,2],[29.7,9.02,0.0],29.7,22,15,14,[0,2,1,1,1,1,0,1,0,1,2,2,1,3,1,0],"10.1002/hep.23527"],[21091279,"Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.","N Engl J Med",2010,"Grant et al.",2,[2,9,12],[29.7,29.7,25.45],29.7,20,15,12,[0,5,1,1,1,1,2,1,2,0,1,1,0,1,2,0],"10.1056/NEJMoa1011205"],[23228172,"Abiraterone in metastatic prostate cancer without previous chemotherapy.","N Engl J Med",2013,"Ryan et al.",2,[1,8,9],[29.7,29.7,29.7],29.7,19,15,12,[0,0,3,1,2,2,1,1,1,0,1,0,3,1,2,1],"10.1056/NEJMoa1209096"],[29342393,"Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer.","N Engl J Med",2018,"van Driel et al.",2,[1,9,7],[29.7,26.17,21.36],29.7,18,17,13,[0,0,0,0,0,0,0,1,5,2,0,2,2,2,2,1],"10.1056/NEJMoa1708618"],[23636398,"Integrated genomic characterization of endometrial carcinoma.","Nature",2013,"Kandoth et al.",7,[1,9],[26.81,25.49],29.69,18,16,13,[0,0,0,0,0,0,0,1,1,1,1,1,4,3,3,2],"10.1038/nature12113"],[24337046,"International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma.","Eur Respir J",2014,"Chung et al.",7,[3,12],[27.59,27.59],29.69,16,16,13,[0,0,0,0,4,0,1,1,1,3,0,1,1,2,0,2],"10.1183/09031936.00202013"],[25919526,"Effect of a retrievable inferior vena cava filter plus anticoagulation vs anticoagulation alone on risk of recurrent pulmonary embolism: a randomized clinical trial.","JAMA",2015,"Mismetti et al.",2,[0,3],[29.69,11.38],29.69,20,16,13,[0,0,0,0,0,1,1,3,1,4,3,0,0,2,2,1],"10.1001/jama.2015.3780"],[26211824,"Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials.","Lancet",2015,"Early Breast Cancer Trialists' Collabora",0,[1],[27.59],29.69,17,16,13,[0,0,0,0,1,1,3,0,2,2,1,0,0,4,2,1],"10.1016/S0140-6736(15)60908-4"],[32227755,"Initial Invasive or Conservative Strategy for Stable Coronary Disease.","N Engl J Med",2020,"Maron et al.",2,[0],[25.88],29.67,26,19,16,[0,0,0,0,0,0,0,0,0,0,2,6,3,5,3,1],"10.1056/NEJMoa1915922"],[10376614,"Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF).","Lancet",1999,"",2,[0],[29.64],29.64,32,22,10,[1,4,1,1,2,4,2,3,1,3,0,0,2,0,0,0],""],[17368234,"Impact of Clostridium difficile on inflammatory bowel disease.","Clin Gastroenterol Hepatol",2007,"Issa et al.",5,[4,2],[28.67,8.47],29.61,18,16,11,[2,1,0,1,1,1,1,3,1,0,2,0,1,2,1,1],"10.1016/j.cgh.2006.12.028"],[20824724,"First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas.","Cancer",2011,"Strosberg et al.",5,[1,4,7],[29.59,21.7,21.7],29.59,16,15,15,[0,3,3,2,4,1,1,0,0,0,0,0,0,0,1,0],"10.1002/cncr.25425"],[15886381,"Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.","JAMA",2005,"Bischoff-Ferrari et al.",0,[13],[16.6],29.54,18,15,14,[1,0,4,1,1,2,4,2,1,1,0,0,1,0,0,0],"10.1001/jama.293.18.2257"],[20889105,"Managing incidental findings on abdominal CT: white paper of the ACR incidental findings committee.","J Am Coll Radiol",2010,"Berland et al.",7,[1,8,7],[25.18,2.69,13.27],29.54,17,15,14,[1,2,0,1,0,1,1,5,1,2,1,0,0,1,0,0],"10.1016/j.jacr.2010.06.013"],[26323938,"Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure.","N Engl J Med",2015,"Cowie et al.",2,[0,5,3],[18.33,8.47,6.2],29.54,26,17,12,[0,0,0,0,0,2,5,1,1,2,1,2,1,2,2,0],"10.1056/NEJMoa1506459"],[26935559,"The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours.","Eur Urol",2016,"Moch et al.",6,[1,8,9],[27.39,28.86,15.12],29.54,27,19,12,[0,0,0,0,0,4,0,3,2,3,2,3,2,3,2,3],"10.1016/j.eururo.2016.02.029"],[16267758,"Risk factors for perinatal transmission of hepatitis C virus (HCV) and the natural history of HCV infection acquired in infancy.","J Infect Dis",2005,"Mast et al.",7,[2,4,9],[24.56,20.99,7.97],29.5,17,14,13,[0,2,1,3,0,2,0,1,1,1,3,1,1,0,0,1],"10.1086/497701"],[17000884,"Secondary prevention of venous thromboembolic events in patients with active cancer: enoxaparin alone versus initial enoxaparin followed by warfarin for a 180-day period.","Clin Appl Thromb Hemost",2006,"Deitcher et al.",2,[0,1],[27.3,17.76],29.5,16,14,13,[1,1,2,1,0,1,0,0,1,1,4,0,0,1,1,1],"10.1177/1076029606293692"],[17018804,"Trends in sudden cardiovascular death in young competitive athletes after implementation of a preparticipation screening program.","JAMA",2006,"Corrado et al.",7,[0],[27.3],29.5,23,16,12,[0,1,1,3,1,2,2,0,2,1,0,0,0,1,1,1],"10.1001/jama.296.13.1593"],[20091560,"Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis.","Cochrane Database Syst Rev",2010,"Marshall et al.",0,[4],[29.5],29.5,17,14,14,[1,2,0,0,2,0,2,3,1,1,1,0,1,1,2,0],"10.1002/14651858.CD004115.pub2"],[21793988,"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.","Clin Microbiol Infect",2012,"Magiorakos et al.",4,[2],[19.76],29.5,16,14,13,[0,0,0,1,1,1,3,2,3,1,1,0,0,1,1,1],"10.1111/j.1469-0691.2011.03570.x"],[25710659,"Anticoagulant reversal, blood pressure levels, and anticoagulant resumption in patients with anticoagulation-related intracerebral hemorrhage.","JAMA",2015,"Kuramatsu et al.",5,[0,5],[27.3,8.71],29.5,22,16,12,[0,0,0,0,2,2,1,5,1,1,0,1,2,1,1,1],"10.1001/jama.2015.0846"],[35767897,"International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.","Blood",2022,"Arber et al.",4,[10,1],[26.12,18.03],29.5,26,26,13,[0,0,0,0,0,0,0,0,0,0,0,0,8,8,4,6],"10.1182/blood.2022015850"],[10770721,"Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis.","Clin Infect Dis",2000,"Li et al.",7,[0,2],[26.31,10.68],29.48,29,17,11,[1,1,2,1,4,1,1,0,2,0,1,2,0,1,2,0],"10.1086/313753"],[15262104,"Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial.","Lancet",2004,"Grigor et al.",2,[11],[29.48],29.48,18,17,11,[2,2,1,1,1,1,2,1,1,0,0,0,0,2,1,2],"10.1016/S0140-6736(04)16676-2"],[18635428,"Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.","N Engl J Med",2008,"Shai et al.",2,[7],[27.24],29.48,18,15,12,[2,1,2,1,3,1,0,3,1,1,0,1,1,0,0,1],"10.1056/NEJMoa0708681"],[35660797,"PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer.","N Engl J Med",2022,"Cercek et al.",3,[1,4],[27.79,25.4],29.48,18,18,17,[0,0,0,0,0,0,0,0,0,0,0,0,1,7,7,3],"10.1056/NEJMoa2201445"],[10784581,"Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer.","Gastroenterology",2000,"Järvinen et al.",3,[1,4,7],[29.4,24.49,17.85],29.4,18,15,17,[1,0,3,4,3,0,0,1,0,1,1,0,0,0,0,1],"10.1016/s0016-5085(00)70168-5"],[17634462,"Vitamin D deficiency.","N Engl J Med",2007,"Holick",6,[7],[27.36],29.4,15,15,14,[2,3,1,1,0,0,2,3,0,1,2,0,0,0,0,0],"10.1056/NEJMra070553"],[8550036,"Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club.","Hepatology",1996,"Arroyo et al.",4,[4,8],[27.79,9.02],29.38,16,16,12,[0,1,1,0,1,1,1,3,1,0,4,0,0,1,2,0],"10.1002/hep.510230122"],[17443465,"Liposomal amphotericin B as initial therapy for invasive mold infection: a randomized trial comparing a high-loading dose regimen with standard dosing (AmBiLoad trial).","Clin Infect Dis",2007,"Cornely et al.",2,[2,3],[29.38,6.2],29.38,16,16,13,[2,0,1,2,0,2,1,1,2,0,1,0,0,1,3,0],"10.1086/514341"],[19996459,"Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort.","BMJ",2009,"Mulrooney et al.",5,[1,0],[27.28,9.48],29.38,15,14,14,[0,3,1,0,2,3,0,1,0,0,1,1,2,0,0,1],"10.1136/bmj.b4606"],[26566246,"Antiviral therapy for chronic hepatitis B viral infection in adults: A systematic review and meta-analysis.","Hepatology",2016,"Lok et al.",0,[4,2],[29.38,25.18],29.38,20,14,15,[0,0,0,0,0,0,1,2,2,2,3,2,1,0,2,2],"10.1002/hep.28280"],[21160056,"Heart disease and stroke statistics--2011 update: a report from the American Heart Association.","Circulation",2011,"Roger et al.",7,[0,5],[25.65,2.69],29.36,27,22,12,[8,5,3,2,1,1,0,0,1,1,0,0,0,1,0,0],"10.1161/CIR.0b013e3182009701"],[24011548,"Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial.","Lancet",2013,"Thiele et al.",2,[0],[29.36],29.36,23,17,11,[0,0,0,2,2,2,1,1,1,1,1,1,1,1,3,1],"10.1016/S0140-6736(13)61783-3"],[25623219,"Multimodality imaging of diseases of the thoracic aorta in adults: from the American Society of Echocardiography and the European Association of Cardiovascular Imaging: endorsed by the Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance.","J Am Soc Echocardiogr",2015,"Goldstein et al.",6,[0],[28.84],29.36,31,22,9,[0,0,0,0,0,1,3,2,2,3,2,3,4,1,2,1],"10.1016/j.echo.2014.11.015"],[14999112,"The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease.","N Engl J Med",2004,"Celli et al.",5,[3],[29.35],29.35,20,18,13,[2,3,4,2,1,1,4,0,0,0,0,0,0,0,1,0],"10.1056/NEJMoa021322"],[9673301,"Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.","N Engl J Med",1998,"Haffner et al.",5,[0,7],[20.7,19.39],29.33,23,19,11,[1,4,5,3,0,0,1,0,2,0,1,1,0,2,0,0],"10.1056/NEJM199807233390404"],[17482982,"Micafungin versus liposomal amphotericin B for candidaemia and invasive candidosis: a phase III randomised double-blind trial.","Lancet",2007,"Kuse et al.",2,[2],[26.46],29.33,18,17,12,[3,3,3,1,0,1,2,2,0,0,0,0,0,1,0,1],"10.1016/S0140-6736(07)60605-9"],[18372465,"Inflammatory bowel disease diagnosed with US, MR, scintigraphy, and CT: meta-analysis of prospective studies.","Radiology",2008,"Horsthuis et al.",0,[4],[29.28],29.28,15,14,12,[1,0,1,1,1,1,1,2,1,1,1,0,1,2,1,0],"10.1148/radiol.2471070611"],[19392863,"Meta-analysis: surveillance with ultrasound for early-stage hepatocellular carcinoma in patients with cirrhosis.","Aliment Pharmacol Ther",2009,"Singal et al.",0,[4,1],[29.28,24.67],29.28,22,14,14,[1,3,2,0,2,1,1,1,1,1,0,1,0,1,2,1],"10.1111/j.1365-2036.2009.04014.x"],[19843914,"The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk: the TRENDS study.","Circ Arrhythm Electrophysiol",2009,"Glotzer et al.",5,[0,5],[29.28,8.97],29.28,26,16,12,[1,2,0,2,1,3,1,2,1,2,2,1,0,1,1,0],"10.1161/CIRCEP.109.849638"],[18768945,"Hyponatremia and mortality among patients on the liver-transplant waiting list.","N Engl J Med",2008,"Kim et al.",7,[4,7],[22.43,4.65],29.26,19,18,14,[0,0,0,1,0,2,0,2,0,0,4,0,0,2,5,2],"10.1056/NEJMoa0801209"],[31433515,"The 2019 WHO classification of tumours of the digestive system.","Histopathology",2020,"Nagtegaal et al.",7,[1,4],[27.28,27.28],29.26,16,16,14,[0,0,0,0,0,0,0,0,0,1,1,2,2,3,3,4],"10.1111/his.13975"],[15940616,"A randomized, double-blind, controlled withdrawal trial in Crohn's disease patients in long-term remission on azathioprine.","Gastroenterology",2005,"Lémann et al.",2,[4],[29.17],29.17,18,18,11,[3,1,2,3,0,1,3,2,1,1,0,0,0,1,0,0],"10.1053/j.gastro.2005.03.031"],[16391903,"The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1).","Diabetologia",2006,"Ramachandran et al.",2,[7],[23.98],29.17,20,16,13,[2,1,2,1,3,1,0,3,0,1,1,0,0,3,0,0],"10.1007/s00125-005-0097-z"],[17304653,"Immune responses following administration of influenza and pneumococcal vaccines to patients with rheumatoid arthritis receiving adalimumab.","J Rheumatol",2007,"Kaine et al.",2,[11],[22.16],29.17,20,16,12,[5,0,1,0,1,1,1,0,3,1,1,0,1,0,0,2],""],[19001508,"Irbesartan in patients with heart failure and preserved ejection fraction.","N Engl J Med",2008,"Massie et al.",2,[0],[29.15],29.15,26,15,12,[0,1,1,1,0,1,4,2,2,1,1,1,1,0,0,1],"10.1056/NEJMoa0805450"],[28158501,"Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders.","J Crohns Colitis",2017,"Magro et al.",4,[4,1],[29.15,2.0],29.15,20,18,13,[0,0,0,0,0,0,0,3,1,2,3,0,2,3,5,1],"10.1093/ecco-jcc/jjx008"],[21236730,"Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial.","Lancet Oncol",2011,"Nutting et al.",2,[1,16],[26.34,13.73],29.12,22,17,11,[0,0,2,2,1,4,1,0,1,0,1,3,0,2,2,3],"10.1016/S1470-2045(10)70290-4"],[14517785,"Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis.","Gastroenterology",2003,"Van Assche et al.",2,[4],[29.1],29.1,20,16,12,[1,2,1,0,1,0,4,2,1,2,0,0,2,1,2,1],"10.1016/s0016-5085(03)01214-9"],[17681169,"Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis.","Gastroenterology",2007,"Ripoll et al.",2,[4,5,7],[29.05,0.0,0.0],29.05,17,16,13,[0,2,1,0,1,0,2,3,0,0,2,0,0,4,1,0],"10.1053/j.gastro.2007.05.024"],[17903236,"Systematic review: Endoscopic dilatation in Crohn's disease.","Aliment Pharmacol Ther",2007,"Hassan et al.",1,[4],[29.02],29.02,15,15,13,[2,1,2,1,2,0,2,3,0,0,0,1,0,1,0,0],"10.1111/j.1365-2036.2007.03532.x"],[22743675,"Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations.","Eur Respir J",2012,"Quanjer et al.",7,[3],[12.65],29.02,16,15,14,[0,0,2,2,0,1,1,0,0,2,1,0,3,0,2,2],"10.1183/09031936.00080312"],[23589584,"Increased prevalence of sleep-disordered breathing in adults.","Am J Epidemiol",2013,"Peppard et al.",5,[5,3,7],[18.57,12.63,4.04],29.02,18,15,13,[0,0,0,0,2,2,4,1,1,0,0,1,0,1,1,3],"10.1093/aje/kws342"],[24635773,"A randomized trial of protocol-based care for early septic shock.","N Engl J Med",2014,"Yealy et al.",2,[2],[9.02],29.02,19,15,13,[0,0,0,1,2,2,1,0,2,5,0,0,0,1,2,1],"10.1056/NEJMoa1401602"],[9603539,"Prediction of coronary heart disease using risk factor categories.","Circulation",1998,"Wilson et al.",5,[0],[26.85],28.94,24,20,11,[0,4,3,4,0,1,1,2,2,0,0,0,0,3,1,0],"10.1161/01.cir.97.18.1837"],[10938172,"The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making.","JAMA",2000,"Antman et al.",2,[0],[28.91],28.91,30,21,10,[4,2,1,3,3,2,3,2,1,0,0,2,0,0,1,0],"10.1001/jama.284.7.835"],[23724913,"Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.","N Engl J Med",2013,"Shaw et al.",2,[1,3],[28.91,22.4],28.91,18,15,13,[0,0,1,3,3,2,2,1,1,0,0,1,1,2,1,0],"10.1056/NEJMoa1214886"],[17258735,"A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis.","Gastroenterology",2007,"D'Haens et al.",6,[4],[28.89],28.89,17,15,11,[2,1,1,1,3,1,1,1,2,1,0,0,1,1,1,0],"10.1053/j.gastro.2006.12.038"],[10408484,"Early Lung Cancer Action Project: overall design and findings from baseline screening.","Lancet",1999,"Henschke et al.",7,[3,1],[28.86,26.71],28.86,15,14,13,[0,2,2,1,2,1,0,3,0,0,1,0,1,1,0,1],"10.1016/S0140-6736(99)06093-6"],[14724827,"Early is superior to deferred preemptive lamivudine therapy for hepatitis B patients undergoing chemotherapy.","Gastroenterology",2003,"Lau et al.",2,[2,4],[19.2,19.2],28.86,19,14,13,[1,3,2,0,0,3,0,1,2,2,1,1,0,0,2,0],"10.1053/j.gastro.2003.09.026"],[14747243,"Management of diabetes and hyperglycemia in hospitals.","Diabetes Care",2004,"Clement et al.",6,[7],[28.86],28.86,19,14,13,[5,2,2,2,1,1,0,3,0,1,0,0,0,1,0,1],"10.2337/diacare.27.2.553"],[16525137,"A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B.","N Engl J Med",2006,"Chang et al.",2,[2,4],[26.71,26.71],28.86,17,14,13,[0,6,2,1,0,2,1,0,1,1,0,1,0,0,1,1],"10.1056/NEJMoa051285"],[17253476,"Follow-up strategies for patients treated for non-metastatic colorectal cancer.","Cochrane Database Syst Rev",2007,"Jeffery et al.",0,[1,4],[28.86,28.86],28.86,18,14,15,[1,1,4,0,3,1,2,1,0,1,0,0,0,0,1,1],"10.1002/14651858.CD002200.pub2"],[17715409,"Long-term mortality after gastric bypass surgery.","N Engl J Med",2007,"Adams et al.",5,[7,0,1],[21.86,1.0,0.0],28.86,20,16,14,[4,1,1,0,1,2,2,2,1,2,0,0,0,1,0,0],"10.1056/NEJMoa066603"],[18003941,"Neuropathic pain: redefinition and a grading system for clinical and research purposes.","Neurology",2008,"Treede et al.",4,[5],[18.36],28.86,14,14,13,[3,1,2,1,0,1,0,2,1,1,0,1,0,0,1,0],"10.1212/01.wnl.0000282763.29778.59"],[18785620,"Utility of serum tumor markers, imaging, and biliary cytology for detecting cholangiocarcinoma in primary sclerosing cholangitis.","Hepatology",2008,"Charatcharoenwitthaya et al.",5,[4,1],[26.71,9.77],28.86,15,14,13,[0,1,2,0,2,0,2,1,1,0,0,1,2,2,0,1],"10.1002/hep.22441"],[19797280,"A multicenter, randomized trial of treatment for mild gestational diabetes.","N Engl J Med",2009,"Landon et al.",2,[7,9],[28.86,25.18],28.86,21,14,14,[3,1,1,4,2,1,1,4,1,2,0,0,0,0,0,0],"10.1056/NEJMoa0902430"],[20022809,"Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial.","Lancet Oncol",2010,"Mitsudomi et al.",2,[1,3],[26.05,26.05],28.86,18,14,15,[1,2,4,1,2,0,1,0,1,1,0,0,2,1,0,0],"10.1016/S1470-2045(09)70364-X"],[20664402,"Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis.","Obstet Gynecol",2010,"Bujold et al.",0,[9,17],[21.86,5.08],28.86,17,14,13,[0,0,2,0,0,1,1,3,2,0,2,1,1,1,0,1],"10.1097/AOG.0b013e3181e9322a"],[21098742,"Pregnancy outcomes after maternal exposure to rituximab.","Blood",2011,"Chakravarty et al.",7,[9,17],[10.83,1.0],28.86,15,14,13,[0,1,1,0,1,0,1,1,1,1,0,0,2,0,2,3],"10.1182/blood-2010-07-295444"],[21447489,"Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 2: intensive care and emergency departments.","Br J Anaesth",2011,"Cook et al.",5,[3,5],[20.63,6.2],28.86,17,16,12,[0,2,2,0,1,1,1,1,0,0,0,3,0,2,2,1],"10.1093/bja/aer059"],[22231479,"Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study.","Arthritis Rheum",2012,"Rovin et al.",2,[11,8],[23.95,9.02],28.86,16,14,13,[0,0,2,0,1,1,0,1,1,0,2,0,1,2,2,3],"10.1002/art.34359"],[22686416,"Basal insulin and cardiovascular and other outcomes in dysglycemia.","N Engl J Med",2012,"Gerstein et al.",2,[7,0],[23.28,9.02],28.86,18,14,15,[0,0,2,1,1,3,0,2,2,0,0,1,1,1,0,1],"10.1056/NEJMoa1203858"],[25738668,"Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy.","N Engl J Med",2015,"Moore et al.",2,[1,9,7],[23.08,9.17,4.65],28.86,17,14,13,[0,0,0,0,1,2,2,2,3,2,0,1,0,1,1,1],"10.1056/NEJMoa1413204"],[20351327,"Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer.","J Clin Oncol",2010,"Aupérin et al.",0,[1,3],[28.85,28.85],28.85,20,16,13,[0,0,3,0,1,3,3,0,0,2,1,2,0,0,5,0],"10.1200/JCO.2009.26.2543"],[18620949,"Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial.","Lancet",2008,"Eggermont et al.",2,[1,14],[28.82,28.82],28.82,18,15,13,[1,4,3,0,1,4,0,0,1,1,0,1,1,0,0,0],"10.1016/S0140-6736(08)61033-8"],[24656685,"Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials.","Lancet",2014,"McGale et al.",0,[1],[28.82],28.82,24,15,14,[0,0,0,1,4,4,3,0,2,0,1,2,0,2,2,0],"10.1016/S0140-6736(14)60488-8"],[24678939,"A controlled trial of renal denervation for resistant hypertension.","N Engl J Med",2014,"Bhatt et al.",2,[0],[28.82],28.82,18,17,12,[0,0,0,2,2,4,0,3,1,1,0,0,0,3,1,1],"10.1056/NEJMoa1402670"],[17124018,"Bivalirudin for patients with acute coronary syndromes.","N Engl J Med",2006,"Stone et al.",2,[0],[28.81],28.81,33,20,10,[4,6,4,2,4,1,0,1,1,1,1,0,0,0,1,0],"10.1056/NEJMoa062437"],[8313552,"Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses.","Circulation",1994,"Cannegieter et al.",6,[0],[24.28],28.77,33,16,11,[0,4,2,2,1,1,2,2,1,0,1,1,1,3,0,0],"10.1161/01.cir.89.2.635"],[12378366,"The epidemiology of corticosteroid-induced osteoporosis: a meta-analysis.","Osteoporos Int",2002,"van Staa et al.",0,[7,13],[21.14,21.14],28.77,15,14,12,[1,1,0,1,0,1,2,0,1,0,1,1,1,1,3,1],"10.1007/s001980200108"],[15940371,"Predictive value of BMD for hip and other fractures.","J Bone Miner Res",2005,"Johnell et al.",0,[13],[23.81],28.77,18,14,12,[1,1,2,1,0,2,0,0,2,1,1,1,0,1,3,1],"10.1359/JBMR.050304"],[17509029,"Incidence rates of post-ERCP complications: a systematic survey of prospective studies.","Am J Gastroenterol",2007,"Andriulli et al.",5,[4],[24.87],28.77,17,16,11,[1,1,1,1,1,1,2,1,3,0,2,0,0,0,1,1],"10.1111/j.1572-0241.2007.01279.x"],[20034693,"Liver grafts from anti-hepatitis B core positive donors: a systematic review.","J Hepatol",2010,"Cholongitas et al.",1,[4,2],[23.81,16.43],28.77,19,16,11,[0,2,1,0,1,2,0,1,2,2,1,1,0,3,2,1],"10.1016/j.jhep.2009.11.009"],[28237263,"3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial.","Lancet",2017,"le Roux et al.",2,[7],[25.94],28.73,20,17,14,[0,0,0,0,0,0,0,0,1,4,0,3,2,2,2,4],"10.1016/S0140-6736(17)30069-7"],[36876740,"Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients.","N Engl J Med",2023,"Nissen et al.",2,[0],[19.86],28.73,26,21,17,[0,0,0,0,0,0,0,0,0,0,0,0,1,7,4,10],"10.1056/NEJMoa2215024"],[12891531,"Corticosteroids and immunomodulators: postoperative infectious complication risk in inflammatory bowel disease patients.","Gastroenterology",2003,"Aberra et al.",5,[4,2],[26.56,1.0],28.66,18,16,12,[1,1,0,1,2,0,4,0,1,2,0,0,0,3,3,0],"10.1016/s0016-5085(03)00883-7"],[25773919,"Outcomes of anatomical versus functional testing for coronary artery disease.","N Engl J Med",2015,"Douglas et al.",2,[0],[28.66],28.66,27,18,11,[0,0,0,0,0,1,3,2,0,4,1,5,1,3,1,0],"10.1056/NEJMoa1415516"],[34161051,"Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.","N Engl J Med",2021,"Sartor et al.",2,[1,8,9],[28.66,26.85,26.85],28.66,21,19,14,[0,0,0,0,0,0,0,0,0,0,0,2,7,4,3,5],"10.1056/NEJMoa2107322"],[19272486,"Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis.","Am J Med",2009,"Buchwald et al.",0,[7],[28.59],28.59,21,15,14,[4,2,2,2,2,1,2,1,1,1,0,0,0,0,0,1],"10.1016/j.amjmed.2008.09.041"],[20606150,"Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease.","JAMA",2010,"Cooper-DeHoff et al.",5,[0,7],[18.89,17.21],28.59,24,15,13,[2,2,2,4,1,0,1,0,3,1,0,0,1,1,0,1],"10.1001/jama.2010.884"],[20818903,"Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.","N Engl J Med",2010,"Mehta et al.",2,[0],[28.59],28.59,31,17,11,[4,4,2,2,2,1,1,3,0,1,0,1,0,0,1,0],"10.1056/NEJMoa0909475"],[32223112,"Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer.","N Engl J Med",2020,"Agnelli et al.",2,[0,1],[27.82,20.6],28.57,18,17,15,[0,0,0,0,0,0,0,0,0,0,7,0,2,4,2,2],"10.1056/NEJMoa1915103"],[34185076,"The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.","Neuro Oncol",2021,"Louis et al.",6,[1,5],[28.57,27.33],28.57,19,19,14,[0,0,0,0,0,0,0,0,0,0,0,2,3,2,8,4],"10.1093/neuonc/noab106"],[17299196,"Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score.","JAMA",2007,"Ridker et al.",7,[0],[19.27],28.56,24,18,11,[3,1,2,2,1,2,0,0,3,0,1,2,0,1,0,0],"10.1001/jama.297.6.611"],[23013602,"Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis.","Lancet",2012,"Fox et al.",0,[8,7],[13.27,17.06],28.56,15,14,14,[0,0,0,0,0,0,1,2,1,3,0,2,0,2,1,2],"10.1016/S0140-6736(12)61350-6"],[16698746,"The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications.","Gut",2006,"Satsangi et al.",4,[4],[28.53],28.53,18,16,11,[1,2,1,0,1,0,2,1,1,3,0,0,1,1,4,0],"10.1136/gut.2005.082909"],[16831999,"Diagnostic accuracy of transesophageal echocardiography, helical computed tomography, and magnetic resonance imaging for suspected thoracic aortic dissection: systematic review and meta-analysis.","Arch Intern Med",2006,"Shiga et al.",0,[0],[28.53],28.53,20,16,11,[0,2,0,4,1,1,0,1,1,0,1,2,2,1,0,1],"10.1001/archinte.166.13.1350"],[20152309,"Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review.","Gastrointest Endosc",2010,"Liao et al.",1,[4],[26.34],28.49,15,15,12,[0,0,1,1,3,0,3,0,1,0,1,0,2,1,1,1],"10.1016/j.gie.2009.09.031"],[21366472,"Diuretic strategies in patients with acute decompensated heart failure.","N Engl J Med",2011,"Felker et al.",2,[0],[23.59],28.49,22,15,12,[0,2,2,0,2,2,1,0,1,0,0,0,1,1,2,2],"10.1056/NEJMoa1005419"],[15934081,"Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial.","Arthritis Rheum",2005,"Wanders et al.",2,[11,13],[28.46,23.28],28.46,20,16,13,[2,3,1,3,1,0,2,0,3,0,1,0,2,0,0,0],"10.1002/art.21054"],[23485231,"Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012.","Eur J Cancer",2013,"Ferlay et al.",7,[1],[27.59],28.46,19,16,12,[0,0,3,2,3,2,2,2,1,0,0,0,1,1,0,0],"10.1016/j.ejca.2012.12.027"],[23541457,"A new risk classification system for therapeutic decision making with intermediate-risk prostate cancer patients undergoing dose-escalated external-beam radiation therapy.","Eur Urol",2013,"Zumsteg et al.",5,[1,8,9],[28.46,28.46,28.46],28.46,18,16,12,[0,0,0,0,0,3,3,2,1,2,1,3,0,2,1,0],"10.1016/j.eururo.2013.03.033"],[25773607,"Efficacy and safety of evolocumab in reducing lipids and cardiovascular events.","N Engl J Med",2015,"Sabatine et al.",2,[7,0],[25.31,16.99],28.44,24,17,15,[0,0,0,0,1,5,2,2,5,0,1,0,0,0,0,1],"10.1056/NEJMoa1500858"],[30545968,"Haemodynamic definitions and updated clinical classification of pulmonary hypertension.","Eur Respir J",2019,"Simonneau et al.",6,[0,3],[24.49,14.06],28.44,18,15,15,[0,0,0,0,0,0,0,0,1,2,0,3,2,4,3,1],"10.1183/13993003.01913-2018"],[30665869,"Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet Oncol",2019,"Zhu et al.",2,[1,4],[28.44,28.44],28.44,20,15,16,[0,0,0,0,0,0,0,0,1,2,3,2,1,7,2,0],"10.1016/S1470-2045(18)30937-9"],[32027911,"Association Between Fibrosis Stage and Outcomes of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.","Gastroenterology",2020,"Taylor et al.",0,[4],[24.49],28.44,20,15,15,[0,0,0,0,0,0,0,0,0,1,3,2,2,3,4,2],"10.1053/j.gastro.2020.01.043"],[15152060,"Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy.","N Engl J Med",2004,"Kadish et al.",2,[0,17],[27.85,5.78],28.41,35,23,8,[1,2,2,2,2,3,2,1,2,1,1,2,1,1,1,0],"10.1056/NEJMoa033088"],[15238590,"Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial.","JAMA",2004,"Ferguson et al.",2,[0],[28.34],28.34,30,19,10,[3,5,3,2,4,1,0,1,1,0,1,1,0,0,1,0],"10.1001/jama.292.1.45"],[19766639,"Radioembolization for hepatocellular carcinoma using Yttrium-90 microspheres: a comprehensive report of long-term outcomes.","Gastroenterology",2010,"Salem et al.",3,[1,4],[28.34,28.34],28.34,24,15,13,[2,1,1,0,2,1,3,0,1,0,2,2,1,2,1,1],"10.1053/j.gastro.2009.09.006"],[17602081,"Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 [corrected].","J Clin Oncol",2007,"Maki et al.",2,[1],[28.32],28.32,20,16,11,[1,2,0,1,2,2,2,1,0,0,2,1,2,0,4,0],"10.1200/JCO.2006.10.4117"],[15312864,"Multidisciplinary strategies for the management of heart failure patients at high risk for admission: a systematic review of randomized trials.","J Am Coll Cardiol",2004,"McAlister et al.",1,[0],[28.31],28.31,26,19,9,[2,1,3,3,1,1,1,1,2,3,1,1,1,1,0,0],"10.1016/j.jacc.2004.05.055"],[30137196,"A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).","Ann Oncol",2018,"Mateo et al.",7,[1],[24.33],28.3,45,40,9,[0,0,0,0,0,0,0,0,0,0,1,8,8,10,12,6],"10.1093/annonc/mdy263"],[2407762,"Quantification of coronary artery calcium using ultrafast computed tomography.","J Am Coll Cardiol",1990,"Agatston et al.",7,[0,7],[23.98,6.77],28.28,17,15,12,[2,1,1,0,0,1,1,4,1,0,2,1,0,1,0,0],"10.1016/0735-1097(90)90282-t"],[11913479,"Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload.","Eur Heart J",2001,"Anderson et al.",5,[0,7],[12.13,10.83],28.28,16,15,12,[0,0,3,0,0,1,1,0,1,2,2,3,1,1,1,0],"10.1053/euhj.2001.2822"],[19177576,"Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia.","Hepatology",2009,"International Consensus Group for Hepato",7,[1,4],[28.28,28.28],28.28,19,15,12,[2,2,2,1,1,2,0,2,0,1,0,0,1,3,0,0],"10.1002/hep.22709"],[19272490,"Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials.","Am J Med",2009,"Wald et al.",0,[0],[26.13],28.28,28,15,14,[0,1,1,0,0,2,1,2,2,0,1,0,0,3,2,1],"10.1016/j.amjmed.2008.09.038"],[19588292,"Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED-ECCO consensus.","Endoscopy",2009,"Bourreille et al.",4,[4],[28.28],28.28,15,15,12,[2,1,1,1,3,0,1,2,0,1,0,0,1,0,2,0],"10.1055/s-0029-1214790"],[20843247,"Susceptibility to exacerbation in chronic obstructive pulmonary disease.","N Engl J Med",2010,"Hurst et al.",5,[3],[28.28],28.28,19,17,12,[0,2,2,1,2,1,5,0,0,1,1,1,1,0,0,0],"10.1056/NEJMoa0909883"],[22762315,"Estimating glomerular filtration rate from serum creatinine and cystatin C.","N Engl J Med",2012,"Inker et al.",5,[8],[16.6],28.28,15,15,12,[0,0,1,1,2,0,1,3,1,1,0,0,0,1,3,1],"10.1056/NEJMoa1114248"],[26809111,"Sorafenib or placebo plus TACE with doxorubicin-eluting beads for intermediate stage HCC: The SPACE trial.","J Hepatol",2016,"Lencioni et al.",2,[1,4],[28.28,28.28],28.28,20,15,14,[0,0,0,0,0,0,3,2,1,2,1,2,1,3,2,1],"10.1016/j.jhep.2016.01.012"],[16442208,"Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials.","Eur Urol",2006,"Sylvester et al.",7,[1,8],[28.26,28.26],28.26,24,17,10,[1,2,4,1,1,1,0,3,1,2,0,2,0,2,1,2],"10.1016/j.eururo.2005.12.031"],[15330919,"Postpolypectomy lower gastrointestinal bleeding: potential role of aspirin.","Am J Gastroenterol",2004,"Yousfi et al.",5,[4],[23.3],28.21,18,14,12,[3,3,1,1,1,1,1,1,0,0,1,1,0,0,0,1],"10.1111/j.1572-0241.2004.30368.x"],[16484504,"A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.","Gut",2006,"Ogata et al.",2,[4],[28.21],28.21,19,14,12,[3,1,1,0,2,1,0,3,1,1,0,0,2,1,3,0],"10.1136/gut.2005.081794"],[16754727,"Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial.","JAMA",2006,"Vogel et al.",2,[1],[11.58],28.21,17,14,12,[2,0,2,1,2,1,1,0,3,1,1,1,0,1,0,0],"10.1001/jama.295.23.joc60074"],[18182665,"Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study.","J Clin Oncol",2008,"Berthold et al.",2,[1,8,9],[28.21,27.3,27.3],28.21,19,14,12,[0,2,1,0,2,2,0,1,1,0,1,1,3,2,2,0],"10.1200/JCO.2007.12.4008"],[18946061,"K-ras mutations and benefit from cetuximab in advanced colorectal cancer.","N Engl J Med",2008,"Karapetis et al.",2,[1,4],[28.21,25.1],28.21,27,16,12,[3,2,0,3,2,0,3,2,0,1,1,0,2,3,1,0],"10.1056/NEJMoa0804385"],[19052126,"Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.","N Engl J Med",2008,"Marcellin et al.",2,[2,4],[25.1,24.56],28.21,19,14,12,[1,7,2,0,0,2,1,1,1,1,0,1,0,1,1,0],"10.1056/NEJMoa0802878"],[20816546,"Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind, randomised controlled trial.","Lancet",2010,"Abernethy et al.",2,[3],[25.45],28.21,16,14,13,[1,1,0,2,3,1,1,0,0,1,0,1,1,3,0,1],"10.1016/S0140-6736(10)61115-4"],[21703676,"Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial.","Lancet",2011,"Aujesky et al.",2,[0,3],[28.21,20.63],28.21,17,14,12,[0,1,1,1,1,1,0,1,2,2,2,0,0,0,2,2],"10.1016/S0140-6736(11)60824-6"],[21777972,"Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial.","Lancet",2011,"Burt et al.",2,[11,14],[19.74,11.85],28.21,17,15,14,[0,1,0,0,0,0,4,1,0,1,0,0,1,2,4,2],"10.1016/S0140-6736(11)60982-3"],[23425163,"Extended use of dabigatran, warfarin, or placebo in venous thromboembolism.","N Engl J Med",2013,"Schulman et al.",2,[0],[28.21],28.21,18,14,12,[0,0,2,2,1,1,0,1,1,2,4,0,0,1,1,1],"10.1056/NEJMoa1113697"],[25399551,"Improved overall survival in melanoma with combined dabrafenib and trametinib.","N Engl J Med",2015,"Robert et al.",2,[1,14],[28.21,18.99],28.21,18,14,12,[0,0,0,0,1,1,0,1,2,3,1,1,1,2,4,1],"10.1056/NEJMoa1412690"],[26747333,"Monthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline: A Randomized Clinical Trial.","JAMA Intern Med",2016,"Bischoff-Ferrari et al.",2,[7],[22.09],28.21,16,15,13,[0,0,0,0,0,0,5,2,3,1,0,1,1,1,2,0],"10.1001/jamainternmed.2015.7148"],[27144630,"Functional Anorectal Disorders.","Gastroenterology",2016,"Rao et al.",7,[4],[21.36],28.21,15,15,13,[0,0,0,0,0,0,1,0,0,2,3,1,1,2,4,1],"10.1053/j.gastro.2016.02.009"],[15265847,"Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial.","JAMA",2004,"Wiegman et al.",2,[7,0,17],[26.01,13.73,9.02],28.17,23,17,12,[4,2,1,2,2,0,1,2,0,2,1,1,0,1,0,1],"10.1001/jama.292.3.331"],[20498393,"Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer.","J Clin Oncol",2010,"Sargent et al.",7,[1,4],[28.17,27.57],28.17,19,17,10,[1,2,2,1,0,0,1,1,1,2,1,2,0,3,2,0],"10.1200/JCO.2009.27.1825"],[12421743,"The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients.","Am J Respir Crit Care Med",2002,"Sessler et al.",7,[5],[11.58],28.15,16,14,13,[0,0,3,0,1,0,1,2,0,2,1,0,0,1,2,1],"10.1164/rccm.2107138"],[15300569,"Risk factors for an adverse outcome in early invasive colorectal carcinoma.","Gastroenterology",2004,"Ueno et al.",7,[1,4],[28.15,28.15],28.15,20,14,14,[1,2,2,1,4,0,2,3,0,1,0,0,0,0,2,0],"10.1053/j.gastro.2004.04.022"],[17321857,"Safe use of selected cephalosporins in penicillin-allergic patients: a meta-analysis.","Otolaryngol Head Neck Surg",2007,"Pichichero et al.",0,[2],[17.16],28.15,15,14,13,[2,0,3,1,3,0,1,1,0,0,1,0,0,0,2,1],"10.1016/j.otohns.2006.10.007"],[20149425,"Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study.","Lancet",2010,"Grainge et al.",5,[0,4],[4.65,23.95],28.15,16,14,13,[0,0,0,2,1,2,0,2,1,1,0,0,2,2,3,0],"10.1016/S0140-6736(09)61963-2"],[21459215,"The RESTORE study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema.","Ophthalmology",2011,"Mitchell et al.",2,[15,7,0],[21.24,26.05,23.28],28.15,17,14,13,[1,1,3,2,1,2,2,0,1,2,0,0,0,0,0,0],"10.1016/j.ophtha.2011.01.031"],[23200982,"Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease.","Clin Gastroenterol Hepatol",2013,"Mahadevan et al.",7,[4,9],[9.77,2.69],28.15,14,14,13,[0,0,1,0,2,1,1,1,1,0,4,0,1,0,2,0],"10.1016/j.cgh.2012.11.011"],[23395245,"Frailty in elderly people.","Lancet",2013,"Clegg et al.",6,[],[],28.15,17,14,13,[0,0,0,1,0,2,1,0,2,2,0,1,0,4,2,1],"10.1016/S0140-6736(12)62167-9"],[23455714,"A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa.","Nat Med",2013,"Lu et al.",7,[0,5],[23.28,10.26],28.15,17,14,14,[0,0,1,0,2,4,0,2,1,0,1,2,1,1,0,0],"10.1038/nm.3102"],[25935633,"Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease.","Gastroenterology",2015,"Angulo et al.",5,[4],[26.05],28.15,18,14,15,[0,0,0,0,0,0,1,1,3,1,1,3,1,1,0,3],"10.1053/j.gastro.2015.04.043"],[26762738,"The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer.","J Thorac Oncol",2016,"Goldstraw et al.",7,[1,3],[28.15,25.32],28.15,14,14,13,[0,0,0,0,0,1,1,0,2,4,1,0,2,1,1,1],"10.1016/j.jtho.2015.09.009"],[28118454,"Continuous Glucose Monitoring vs Conventional Therapy for Glycemic Control in Adults With Type 1 Diabetes Treated With Multiple Daily Insulin Injections: The GOLD Randomized Clinical Trial.","JAMA",2017,"Lind et al.",2,[7],[26.05],28.15,15,14,13,[0,0,0,0,0,0,0,1,3,2,2,2,1,1,1,2],"10.1001/jama.2016.19976"],[12517460,"Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials.","Lancet",2003,"Keeley et al.",6,[0],[28.13],28.13,30,21,8,[4,3,3,2,3,0,2,1,0,1,0,1,0,2,2,0],"10.1016/S0140-6736(03)12113-7"],[22025146,"Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial.","J Clin Oncol",2012,"Wells et al.",2,[1,7],[28.12,25.97],28.12,17,16,11,[1,1,0,2,2,0,0,0,1,1,0,1,0,1,6,1],"10.1200/JCO.2011.35.5040"],[33895845,"2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation.","Europace",2021,"Steffel et al.",7,[0,5],[24.47,8.47],28.08,18,18,14,[0,0,0,0,0,0,0,0,0,0,0,1,1,9,1,6],"10.1093/europace/euab065"],[16731999,"Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes: the Treating to New Targets (TNT) study.","Diabetes Care",2006,"Shepherd et al.",2,[7,0],[22.97,14.43],28.06,29,16,12,[2,2,1,3,2,1,0,2,2,3,0,1,1,1,0,1],"10.2337/dc05-2465"],[24881994,"Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.","Lancet",2014,"Rapsomaniki et al.",3,[0],[28.01],28.01,23,15,14,[0,0,0,0,1,0,1,2,2,0,0,0,1,3,4,2],"10.1016/S0140-6736(14)60685-1"],[26284719,"Tinzaparin vs Warfarin for Treatment of Acute Venous Thromboembolism in Patients With Active Cancer: A Randomized Clinical Trial.","JAMA",2015,"Lee et al.",2,[0],[25.97],28.01,19,15,13,[0,0,0,0,0,1,1,1,1,2,8,0,0,2,1,0],"10.1001/jama.2015.9243"],[115569,"The periodic health examination. Canadian Task Force on the Periodic Health Examination.","Can Med Assoc J",1979,"",7,[2],[13.81],27.97,18,17,10,[4,2,3,2,0,1,0,1,1,1,0,0,0,0,1,1],""],[8844239,"The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine.","Intensive Care Med",1996,"Vincent et al.",7,[2],[8.47],27.97,15,13,14,[0,2,1,0,0,1,1,2,0,1,2,0,2,1,1,0],"10.1007/BF01709751"],[9229283,"Case-finding instruments for depression. 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al.",2,[4,2,1],[25.82,23.66,2.69],27.97,17,13,13,[0,3,2,0,0,3,1,1,1,1,1,1,0,0,2,0],"10.1002/hep.22106"],[19652063,"Follicular lymphoma international prognostic index 2: a new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor project.","J Clin Oncol",2009,"Federico et al.",7,[1,10],[27.97,27.97],27.97,17,13,13,[3,1,3,3,1,1,1,0,0,2,1,0,0,0,0,1],"10.1200/JCO.2008.21.3991"],[20614462,"Lactulose versus Polyethylene Glycol for Chronic Constipation.","Cochrane Database Syst Rev",2010,"Lee-Robichaud et al.",0,[4],[18.89],27.97,14,13,13,[0,0,0,1,0,1,1,1,1,2,0,0,1,2,3,1],"10.1002/14651858.CD007570.pub2"],[21735380,"Exercise for preventing and treating osteoporosis in postmenopausal women.","Cochrane Database Syst Rev",2011,"Howe et al.",0,[13,7],[22.44,22.44],27.97,15,13,13,[0,0,2,1,0,0,2,1,3,0,1,2,0,1,1,1],"10.1002/14651858.CD000333.pub2"],[22036019,"Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial.","Lancet",2011,"Burn et al.",2,[1,4,7],[27.97,27.97,18.57],27.97,18,15,15,[0,1,4,1,3,1,0,1,1,1,1,0,0,0,0,1],"10.1016/S0140-6736(11)61049-0"],[22992074,"Hypoglycemia and risk of death in critically ill patients.","N Engl J Med",2012,"Finfer et al.",2,[7],[11.38],27.97,17,13,14,[0,0,1,1,3,1,3,1,0,2,1,1,0,0,1,0],"10.1056/NEJMoa1204942"],[28898379,"Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis: The ACOSOG Z0011 (Alliance) Randomized Clinical Trial.","JAMA",2017,"Giuliano et al.",2,[1],[27.91],27.91,17,16,13,[0,0,0,0,0,0,0,0,1,2,2,1,0,5,2,4],"10.1001/jama.2017.11470"],[20071702,"Preoperative biliary drainage for cancer of the head of the pancreas.","N Engl J Med",2010,"van der Gaag et al.",2,[4,1,7],[27.9,22.16,17.97],27.9,20,17,11,[0,5,2,1,3,1,1,0,0,0,0,0,2,2,2,0],"10.1056/NEJMoa0903230"],[24768112,"Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial.","Lancet",2014,"Brose et al.",2,[1,7],[27.9,25.13],27.9,18,17,11,[0,0,0,0,1,2,1,0,1,1,0,2,0,1,8,1],"10.1016/S0140-6736(14)60421-9"],[36027570,"Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.","N Engl J Med",2022,"Solomon et al.",2,[0],[19.43],27.89,27,22,14,[0,0,0,0,0,0,0,0,0,0,0,0,5,9,4,4],"10.1056/NEJMoa2206286"],[15131794,"Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study.","Gastroenterology",2004,"Brugge et al.",7,[4,1,7],[27.86,25.27,24.62],27.86,18,18,11,[2,3,2,3,0,3,0,2,0,0,0,0,0,2,1,0],"10.1053/j.gastro.2004.02.013"],[15455194,"Alcohol intake as a risk factor for fracture.","Osteoporos Int",2005,"Kanis et al.",0,[13,7],[27.84,27.84],27.84,17,13,12,[1,1,2,0,0,1,0,1,3,1,1,2,0,1,1,1],"10.1007/s00198-004-1734-y"],[15951574,"Effect of treatment of gestational diabetes mellitus on pregnancy outcomes.","N Engl J Med",2005,"Crowther et al.",2,[7,9],[25.1,24.19],27.84,21,13,13,[3,1,1,4,2,1,1,2,1,2,1,0,0,0,0,1],"10.1056/NEJMoa042973"],[11313301,"Intravenous cyclosporine versus intravenous corticosteroids as single therapy for severe attacks of ulcerative colitis.","Gastroenterology",2001,"D'Haens et al.",2,[4],[27.83],27.83,18,15,11,[3,0,1,1,3,1,3,0,1,1,0,0,2,1,1,0],"10.1053/gast.2001.23983"],[12584368,"Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease.","N Engl J Med",2003,"Baert et al.",3,[4],[25.08],27.83,16,15,11,[2,2,1,2,2,0,2,1,1,0,1,0,0,1,1,0],"10.1056/NEJMoa020888"],[18165667,"Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial.","JAMA",2007,"Anderson et al.",2,[0,3],[27.83,15.2],27.83,19,15,11,[2,0,0,2,0,0,2,2,2,1,2,1,0,1,1,1],"10.1001/jama.298.23.2743"],[18471512,"Terlipressin and albumin vs albumin in patients with cirrhosis and hepatorenal syndrome: a randomized study.","Gastroenterology",2008,"Martín-Llahí et al.",2,[4,8],[26.34,7.97],27.83,15,15,11,[0,1,1,0,1,2,1,3,1,0,1,1,1,2,0,0],"10.1053/j.gastro.2008.02.024"],[22204725,"A phase 3 trial of bevacizumab in ovarian cancer.","N Engl J Med",2011,"Perren et al.",2,[1,9,7],[27.83,27.83,25.08],27.83,18,15,11,[0,1,1,1,1,0,1,0,3,1,4,1,1,3,0,0],"10.1056/NEJMoa1103799"],[22503032,"Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.","Lancet Oncol",2012,"Hofheinz et al.",2,[1,4],[27.83,23.43],27.83,21,15,11,[0,2,2,1,1,0,3,3,0,2,0,0,1,1,3,1],"10.1016/S1470-2045(12)70116-X"],[10833208,"A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators.","N Engl J Med",2000,"Feagan et al.",2,[4],[27.79],27.79,16,15,12,[1,1,0,2,1,0,4,1,1,0,0,0,0,3,2,0],"10.1056/NEJM200006013422202"],[16014882,"Erlotinib in previously treated non-small-cell lung cancer.","N Engl J Med",2005,"Shepherd et al.",2,[1,3],[26.17,26.92],27.79,20,15,14,[4,3,4,2,1,0,1,1,1,0,1,0,0,0,0,0],"10.1056/NEJMoa050753"],[18363820,"Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study.","J Thromb Haemost",2008,"Jacobsen et al.",5,[0,9],[23.28,13.38],27.79,15,15,12,[0,3,3,1,1,2,0,1,2,0,0,0,1,0,0,1],"10.1111/j.1538-7836.2008.02961.x"],[18425970,"Traditional corticosteroids for induction of remission in Crohn's disease.","Cochrane Database Syst Rev",2008,"Benchimol et al.",0,[4],[27.79],27.79,16,15,12,[1,0,1,1,0,0,3,2,2,1,0,0,0,3,2,0],"10.1002/14651858.CD006792.pub2"],[18471513,"A randomized, prospective, double-blind, placebo-controlled trial of terlipressin for type 1 hepatorenal syndrome.","Gastroenterology",2008,"Sanyal et al.",2,[4,8],[26.17,7.47],27.79,15,15,12,[0,1,1,0,1,2,0,3,0,0,2,1,1,3,0,0],"10.1053/j.gastro.2008.02.014"],[19058754,"Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis.","Lancet Oncol",2009,"Mazzaferro et al.",5,[4,1],[27.79,23.95],27.79,19,15,13,[0,1,1,0,2,1,0,1,0,0,1,0,1,6,2,0],"10.1016/S1470-2045(08)70284-5"],[22578793,"Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.","Lancet Oncol",2012,"Wick et al.",2,[1,5],[27.79,22.09],27.79,16,15,12,[0,0,2,2,1,3,2,1,0,0,0,2,0,1,2,0],"10.1016/S1470-2045(12)70164-X"],[24240932,"Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial.","JAMA",2013,"Abed et al.",2,[0,7],[27.79,0.0],27.79,24,15,12,[0,1,0,0,0,3,2,4,1,2,1,1,0,4,0,0],"10.1001/jama.2013.280521"],[28591523,"Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma.","N Engl J Med",2017,"Faries et al.",2,[1,14],[27.79,27.79],27.79,19,15,12,[0,0,0,0,0,0,0,1,4,4,2,1,1,1,2,1],"10.1056/NEJMoa1613210"],[31566307,"Nintedanib in Progressive Fibrosing Interstitial Lung Diseases.","N Engl J Med",2019,"Flaherty et al.",2,[3],[25.11],27.79,23,17,14,[0,0,0,0,0,0,0,0,0,0,4,3,2,4,4,3],"10.1056/NEJMoa1908681"],[15175436,"Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.","N Engl J Med",2004,"André et al.",2,[1,4],[27.71,27.71],27.71,20,16,11,[2,3,3,0,0,0,2,2,1,1,0,2,0,1,2,0],"10.1056/NEJMoa032709"],[17075810,"Hydroxychloroquine in lupus pregnancy.","Arthritis Rheum",2006,"Clowse et al.",3,[11,9],[22.83,7.97],27.71,19,16,12,[0,3,0,0,2,0,2,1,1,2,1,0,1,0,3,1],"10.1002/art.22159"],[12905464,"Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report.","Arthritis Rheum",2003,"Gómez-Reino et al.",5,[11,2,3],[16.74,6.48,1.0],27.66,16,16,12,[4,6,1,0,1,1,0,1,1,0,0,0,0,0,1,0],"10.1002/art.11137"],[24529560,"Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis.","Lancet",2014,"Cortazar et al.",6,[1],[27.66],27.66,20,16,12,[0,0,0,0,3,1,1,0,3,0,2,0,0,5,1,4],"10.1016/S0140-6736(13)62422-8"],[27040132,"Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease.","N Engl J Med",2016,"Yusuf et al.",2,[0,7],[26.81,17.76],27.66,27,16,13,[0,0,0,0,0,2,0,4,4,1,3,3,0,1,0,3],"10.1056/NEJMoa1600176"],[28564564,"Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy.","N Engl J Med",2017,"Masuda et al.",2,[1],[27.66],27.66,20,16,12,[0,0,0,0,0,0,0,1,1,2,3,3,0,4,2,2],"10.1056/NEJMoa1612645"],[10963635,"Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved international normalized ratio: a retrospective analysis.","J Clin Oncol",2000,"Hutten et al.",5,[0,1],[27.62,19.76],27.62,17,15,11,[1,2,3,1,0,2,0,1,2,2,0,0,1,1,1,0],"10.1200/JCO.2000.18.17.3078"],[23870728,"European consensus on the histopathology of inflammatory bowel disease.","J Crohns Colitis",2013,"Magro et al.",4,[4,1],[27.62,2.69],27.62,15,15,11,[0,0,1,1,1,1,1,2,2,2,1,0,0,0,1,2],"10.1016/j.crohns.2013.06.001"],[11955536,"Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial.","Lancet",2002,"Braun et al.",2,[11,13],[15.56,15.56],27.6,17,14,13,[3,2,3,1,2,0,1,1,2,0,1,0,1,0,0,0],"10.1016/s0140-6736(02)08215-6"],[12435255,"Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial.","JAMA",2002,"Wright et al.",2,[0,8],[20.25,9.77],27.6,22,14,13,[0,0,2,3,1,0,0,1,2,0,2,1,0,1,1,1],"10.1001/jama.288.19.2421"],[12796126,"Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial.","Circulation",2003,"Chung et al.",2,[0],[1.0],27.6,16,14,12,[2,2,0,1,1,1,1,0,2,0,2,1,0,1,0,0],"10.1161/01.CIR.0000077913.60364.D2"],[16871531,"Classification criteria for psoriatic arthritis: development of new criteria from a large international study.","Arthritis Rheum",2006,"Taylor et al.",5,[11,13,14],[21.86,21.86,19.76],27.6,15,14,12,[3,2,1,1,1,2,1,0,2,1,0,0,0,0,1,0],"10.1002/art.21972"],[17065637,"Survival of patients with stage I lung cancer detected on CT screening.","N Engl J Med",2006,"Henschke et al.",5,[1,3],[25.45,25.45],27.6,17,14,13,[0,2,2,1,1,2,3,1,0,1,1,0,0,0,0,1],"10.1056/NEJMoa060476"],[18506025,"Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer.","J Clin Oncol",2008,"Scagliotti et al.",2,[1,3],[27.6,27.6],27.6,19,14,13,[2,3,3,2,2,2,1,1,2,1,0,0,0,0,0,0],"10.1200/JCO.2007.15.0375"],[19269519,"Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial.","Lancet",2009,"Sebag-Montefiore et al.",2,[1,4],[27.6,27.6],27.6,18,14,12,[2,0,3,0,3,1,2,2,0,1,1,0,0,1,1,0],"10.1016/S0140-6736(09)60484-0"],[19451574,"Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial.","Ann Intern Med",2009,"de Groot et al.",2,[0,11],[20.63,20.63],27.6,16,14,12,[1,0,0,0,1,1,1,0,1,0,2,1,2,3,2,0],"10.7326/0003-4819-150-10-200905190-00004"],[19638912,"The Clavien-Dindo classification of surgical complications: five-year experience.","Ann Surg",2009,"Clavien et al.",5,[],[],27.6,16,14,12,[0,2,1,0,2,1,3,1,0,1,1,0,0,2,1,0],"10.1097/SLA.0b013e3181b13ca2"],[20233825,"Stereotactic body radiation therapy for inoperable early stage lung cancer.","JAMA",2010,"Timmerman et al.",3,[1,3],[27.6,23.95],27.6,14,14,12,[0,1,3,2,1,2,1,0,0,1,0,1,0,0,1,1],"10.1001/jama.2010.261"],[20696966,"Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism.","Arch Intern Med",2010,"Jiménez et al.",5,[0,3],[27.6,22.72],27.6,18,14,12,[0,1,1,1,1,2,0,1,3,2,3,0,0,0,3,0],"10.1001/archinternmed.2010.199"],[21505219,"Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis.","BMJ",2011,"Bolland et al.",0,[13,7,0],[25.45,23.3,1.0],27.6,16,14,12,[0,1,2,2,1,1,3,2,2,1,0,0,0,0,1,0],"10.1136/bmj.d2040"],[21707680,"Meta-analysis: antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding - an updated Cochrane review.","Aliment Pharmacol Ther",2011,"Chavez-Tapia et al.",0,[4,2],[25.45,1.0],27.6,14,14,12,[0,0,0,0,2,1,1,1,1,2,3,1,1,0,1,0],"10.1111/j.1365-2036.2011.04746.x"],[22252256,"Lifetime cancer risks in individuals with germline PTEN mutations.","Clin Cancer Res",2012,"Tan et al.",5,[1,17],[24.82,9.02],27.6,15,14,12,[0,0,1,1,4,0,0,1,1,1,0,1,0,2,2,1],"10.1158/1078-0432.CCR-11-2283"],[28122885,"Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.","Circulation",2017,"Benjamin et al.",6,[0],[25.71],27.6,23,21,12,[0,0,0,0,0,0,3,7,3,1,6,0,0,0,1,0],"10.1161/CIR.0000000000000485"],[31562799,"Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.","N Engl J Med",2019,"González-Martín et al.",2,[1,9,7],[27.6,25.11,23.21],27.6,18,17,13,[0,0,0,0,0,0,0,0,0,3,3,0,1,8,1,2],"10.1056/NEJMoa1910962"],[8613046,"Methotrexate in chronic active ulcerative colitis: a double-blind, randomized, Israeli multicenter trial.","Gastroenterology",1996,"Oren et al.",2,[4],[27.59],27.59,17,15,12,[2,2,1,1,4,0,1,0,0,3,0,0,2,1,0,0],"10.1053/gast.1996.v110.pm8613046"],[15163773,"Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0 ng per milliliter.","N Engl J Med",2004,"Thompson et al.",2,[1,8,9],[25.49,23.39,23.39],27.59,16,15,12,[1,0,2,3,1,0,2,2,1,0,0,1,0,3,0,0],"10.1056/NEJMoa031918"],[21778438,"Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.","Stroke",2011,"Gorelick et al.",6,[6,5],[15.76,23.39],27.59,16,15,12,[0,3,0,2,1,0,1,3,0,1,0,1,0,1,2,0],"10.1161/STR.0b013e3182299496"],[21997553,"The incidence of oesophageal adenocarcinoma in non-dysplastic Barrett's oesophagus: a meta-analysis.","Gut",2012,"Desai et al.",0,[1,4],[23.39,27.59],27.59,15,15,12,[0,0,0,2,1,1,2,0,2,2,0,0,1,2,2,0],"10.1136/gutjnl-2011-300730"],[24678937,"Transcatheter aortic-valve replacement with a self-expanding prosthesis.","N Engl J Med",2014,"Adams et al.",2,[0],[27.59],27.59,30,15,13,[0,0,0,0,1,2,5,3,2,0,3,1,1,2,0,0],"10.1056/NEJMoa1400590"],[26903337,"Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.","JAMA",2016,"Bellani et al.",5,[3],[25.49],27.59,16,15,11,[0,0,0,0,0,0,3,1,2,2,1,1,0,3,2,1],"10.1001/jama.2016.0291"],[28578607,"Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer.","N Engl J Med",2017,"Fizazi et al.",2,[1,8,9],[27.59,27.03,27.03],27.59,25,17,11,[0,0,0,0,0,0,0,4,2,4,5,2,4,1,2,1],"10.1056/NEJMoa1704174"],[12867608,"Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer.","N Engl J Med",2003,"Ribic et al.",2,[1,4],[27.53,27.05],27.53,21,17,11,[1,1,3,1,1,0,3,1,0,2,1,0,1,2,1,0],"10.1056/NEJMoa022289"],[16271642,"Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.","Lancet",2005,"Chen et al.",2,[0],[23.12],27.52,35,20,11,[5,3,3,2,1,1,2,2,0,2,1,0,0,0,1,0],"10.1016/S0140-6736(05)67660-X"],[25671254,"Lenvatinib versus placebo in radioiodine-refractory thyroid cancer.","N Engl J Med",2015,"Schlumberger et al.",2,[1,7],[27.43,24.46],27.43,16,16,11,[0,0,0,0,1,2,2,0,1,1,0,2,0,1,5,1],"10.1056/NEJMoa1406470"],[24768810,"Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies.","Clin Gastroenterol Hepatol",2015,"Singh et al.",0,[4],[27.41],27.41,19,15,13,[0,0,0,0,1,1,1,0,1,1,2,2,1,3,2,1],"10.1016/j.cgh.2014.04.014"],[10591382,"Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism.","JAMA",1999,"Furlan et al.",2,[0,5],[27.36,27.36],27.36,16,14,13,[3,3,3,1,0,0,0,1,2,0,1,1,0,0,0,0],"10.1001/jama.282.21.2003"],[16287919,"Influence of methotrexate, TNF blockers and prednisolone on antibody responses to pneumococcal polysaccharide vaccine in patients with rheumatoid arthritis.","Rheumatology (Oxford)",2006,"Kapetanovic et al.",5,[11],[20.55],27.36,15,14,13,[4,1,0,1,1,4,0,0,1,0,1,0,0,0,0,1],"10.1093/rheumatology/kei193"],[25182247,"Rivaroxaban vs. vitamin K antagonists for cardioversion in atrial fibrillation.","Eur Heart J",2014,"Cappato et al.",2,[0],[27.36],27.36,22,14,13,[0,0,0,0,1,4,2,5,2,1,0,1,0,2,0,0],"10.1093/eurheartj/ehu367"],[25272316,"Goal-directed resuscitation for patients with early septic shock.","N Engl J Med",2014,"Peake et al.",2,[2],[9.02],27.36,18,14,13,[0,0,0,0,2,2,1,0,2,5,0,0,0,1,2,1],"10.1056/NEJMoa1404380"],[27147121,"Rome IV-Functional GI Disorders: Disorders of Gut-Brain Interaction.","Gastroenterology",2016,"Drossman et al.",7,[4],[21.24],27.36,15,14,13,[0,0,0,0,0,0,0,0,2,1,1,3,1,2,3,1],"10.1053/j.gastro.2016.03.035"],[27222544,"Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations.","Diabetes Care",2016,"Rubino et al.",4,[7],[25.32],27.36,15,14,14,[0,0,0,0,0,0,0,3,1,4,1,1,1,3,0,1],"10.2337/dc16-0236"],[28745999,"Trial of Tocilizumab in Giant-Cell Arteritis.","N Engl J Med",2017,"Stone et al.",2,[0,11,5],[25.32,15.19,13.27],27.36,18,14,13,[0,0,0,0,0,0,0,0,2,2,4,1,2,1,1,2],"10.1056/NEJMoa1613849"],[29498924,"SIRveNIB: Selective Internal Radiation Therapy Versus Sorafenib in Asia-Pacific Patients With Hepatocellular Carcinoma.","J Clin Oncol",2018,"Chow et al.",2,[1,4],[27.36,27.36],27.36,16,14,13,[0,0,0,0,0,0,0,2,0,2,2,3,1,3,1,1],"10.1200/JCO.2017.76.0892"],[28317415,"Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation.","N Engl J Med",2017,"Calkins et al.",2,[0],[27.33],27.33,18,15,14,[0,1,0,0,0,0,0,8,1,1,0,2,0,4,0,0],"10.1056/NEJMoa1701005"],[28845751,"Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.","N Engl J Med",2017,"Ridker et al.",2,[0],[23.54],27.33,19,17,13,[0,0,0,0,0,0,0,0,4,0,2,0,1,7,3,1],"10.1056/NEJMoa1707914"],[1983820,"Reactivation of hepatitis B virus replication in patients receiving cytotoxic therapy. Report of a prospective study.","Gastroenterology",1991,"Lok et al.",5,[2,4,1],[19.76,17.66,11.38],27.3,17,13,12,[1,2,1,2,0,3,1,1,2,0,1,1,0,0,1,0],"10.1016/0016-5085(91)90599-g"],[9058730,"International scoring system for evaluating prognosis in myelodysplastic syndromes.","Blood",1997,"Greenberg et al.",7,[10],[27.3],27.3,17,13,13,[1,1,3,2,1,1,2,0,0,0,1,0,2,1,2,0],""],[16525138,"Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B.","N Engl J Med",2006,"Lai et al.",2,[2,4],[25.1,24.56],27.3,16,13,12,[0,6,1,1,0,1,1,1,1,1,0,1,0,0,1,1],"10.1056/NEJMoa051287"],[17167137,"Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer.","N Engl J Med",2006,"Sandler et al.",2,[1,3],[27.3,25.1],27.3,18,13,13,[2,3,3,2,1,1,1,1,2,1,0,0,1,0,0,0],"10.1056/NEJMoa061884"],[18256392,"HLA-B*5701 screening for hypersensitivity to abacavir.","N Engl J Med",2008,"Mallal et 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Crohn's Disease cA2 Study Group.","N Engl J Med",1997,"Targan et al.",2,[4],[27.23],27.23,17,17,10,[3,1,2,1,0,0,3,1,2,0,0,0,1,2,1,0],"10.1056/NEJM199710093371502"],[9811916,"Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators.","N Engl J Med",1998,"Barnett et al.",2,[0,5],[27.23,23.59],27.23,27,16,11,[4,2,4,4,0,0,1,2,1,1,0,1,0,0,0,0],"10.1056/NEJM199811123392002"],[11794191,"Long-term use of a left ventricular assist device for end-stage heart failure.","N Engl J Med",2001,"Rose et al.",2,[0],[27.23],27.23,22,15,11,[0,4,2,0,1,2,0,1,1,1,0,1,0,2,1,0],"10.1056/NEJMoa012175"],[8606715,"Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group.","N Engl J Med",1996,"Kurz et al.",2,[2],[13.81],27.21,24,16,12,[0,1,2,3,0,0,3,2,2,1,0,0,1,1,0,2],"10.1056/NEJM199605093341901"],[19567909,"The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials.","BMJ",2009,"Brugts et al.",0,[0],[15.0],27.11,25,15,11,[1,1,1,2,1,2,1,1,2,1,1,0,1,2,0,0],"10.1136/bmj.b2376"],[21111555,"Comparative validation of a novel risk score for predicting bleeding risk in anticoagulated patients with atrial fibrillation: the HAS-BLED (Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol Concomitantly) score.","J Am Coll Cardiol",2011,"Lip et al.",2,[0],[27.11],27.11,21,17,12,[0,6,1,1,0,4,0,0,2,0,1,1,0,1,0,0],"10.1016/j.jacc.2010.09.024"],[9297994,"Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.","Lancet",1997,"Staessen et al.",2,[0],[24.33],27.05,23,16,10,[0,1,1,3,2,3,0,1,1,0,1,1,0,1,1,1],"10.1016/s0140-6736(97)05381-6"],[10816184,"Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.","N Engl J Med",2000,"Kress et al.",2,[5,3],[11.58,10.16],27.03,22,16,12,[0,0,4,5,1,1,2,1,0,2,0,1,0,0,1,0],"10.1056/NEJM200005183422002"],[30145929,"Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.","N Engl J Med",2018,"Maurer et al.",2,[0,7,17],[19.84,13.64,8.01],27.03,20,19,11,[0,0,0,0,0,0,0,0,0,3,1,3,1,6,4,1],"10.1056/NEJMoa1805689"],[1852179,"Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.","N Engl J Med",1991,"Barnett et al.",2,[0,5],[27.02,22.72],27.02,24,15,11,[4,1,3,1,0,0,2,1,1,0,0,1,1,2,0,0],"10.1056/NEJM199108153250701"],[12968091,"Sudden death in young athletes.","N Engl J Med",2003,"Maron",6,[0],[24.87],27.02,20,15,11,[2,2,2,1,1,3,1,0,1,0,0,0,0,1,1,0],"10.1056/NEJMra022783"],[15818702,"Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled study.","Arthritis Rheum",2005,"van der Heijde et al.",2,[11,13],[27.02,26.34],27.02,20,15,12,[3,2,1,2,1,0,2,1,3,0,1,0,2,0,0,0],"10.1002/art.20985"],[16980116,"Burden of valvular heart diseases: a population-based study.","Lancet",2006,"Nkomo et al.",7,[0],[27.02],27.02,28,15,11,[1,1,0,3,0,0,2,0,2,2,1,0,1,2,1,0],"10.1016/S0140-6736(06)69208-8"],[18378136,"Phase III randomised study to evaluate the role of adjuvant pelvic radiotherapy in the treatment of uterine sarcomas stages I and II: an European Organisation for Research and Treatment of Cancer Gynaecological Cancer Group Study (protocol 55874).","Eur J Cancer",2008,"Reed et al.",2,[1,9],[27.02,14.1],27.02,18,15,11,[0,1,0,2,0,2,3,1,0,0,1,0,3,1,3,1],"10.1016/j.ejca.2008.01.019"],[24101118,"Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents.","JAMA",2013,"Hawn et al.",5,[0],[22.16],27.02,27,17,11,[0,0,0,4,2,2,2,4,1,1,0,1,1,1,0,0],"10.1001/jama.2013.278787"],[27979383,"Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial.","Lancet",2017,"Rittmeyer et al.",2,[1,3],[27.02,19.39],27.02,21,15,14,[0,0,0,0,0,0,2,3,2,3,1,1,2,3,1,1],"10.1016/S0140-6736(16)32517-X"],[25270275,"Lower versus higher hemoglobin threshold for transfusion in septic shock.","N Engl J Med",2014,"Holst et al.",2,[2],[6.77],27.01,20,15,12,[0,0,0,0,0,1,2,2,2,5,0,0,1,1,3,0],"10.1056/NEJMoa1406617"],[25575710,"Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.","Lancet Neurol",2015,"Finnerup et al.",0,[5],[9.77],27.01,16,15,13,[0,0,0,0,0,0,1,4,0,3,3,1,0,1,1,1],"10.1016/S1474-4422(14)70251-0"],[22144108,"Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis: a randomized trial comparing 3- and 6-month periodicities.","Hepatology",2011,"Trinchet et al.",2,[4,1],[27.0,23.35],27.0,19,13,13,[0,1,1,0,1,1,0,1,1,1,1,2,1,2,2,1],"10.1002/hep.24545"],[32877652,"SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials.","Lancet",2020,"Zannad et al.",0,[0],[14.86],26.99,21,17,13,[0,0,0,0,0,0,0,0,0,0,5,4,1,5,1,1],"10.1016/S0140-6736(20)31824-9"],[23439102,"Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial.","Lancet",2013,"Mohr et al.",2,[0,5],[24.69,0.0],26.93,34,22,8,[0,0,1,5,5,3,2,1,1,0,1,2,1,2,1,0],"10.1016/S0140-6736(13)60141-5"],[7816064,"Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators.","N Engl J Med",1995,"Feagan et al.",2,[4],[26.92],26.92,16,14,11,[2,1,1,1,1,0,2,2,1,1,0,0,0,2,2,0],"10.1056/NEJM199502023320503"],[7977430,"Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer.","Am J Med",1994,"Mazzaferri et al.",3,[1,7],[24.82,26.92],26.92,16,14,12,[1,1,0,1,2,3,0,0,1,2,0,0,0,2,2,0],"10.1016/0002-9343(94)90321-2"],[12510037,"A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients.","N Engl J Med",2003,"Sandham et al.",2,[0,3],[14.77,2.69],26.92,21,14,11,[2,2,2,1,2,0,2,1,1,0,0,1,1,1,0,0],"10.1056/NEJMoa021108"],[12730861,"Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial.","Gastroenterology",2003,"Gionchetti et al.",2,[4],[26.92],26.92,17,14,11,[3,1,2,1,1,0,1,1,1,3,0,0,1,2,0,0],"10.1016/s0016-5085(03)00171-9"],[14762782,"Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.","Gastroenterology",2004,"Rutter et al.",5,[4,1],[24.82,10.26],26.92,17,14,14,[0,0,3,2,2,0,0,3,2,0,2,0,1,1,1,0],"10.1053/j.gastro.2003.11.010"],[15546073,"Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantation.","Clin Infect Dis",2004,"van Burik et al.",2,[2,10],[24.72,6.2],26.92,21,16,10,[4,4,2,1,1,2,0,0,1,0,1,0,1,1,0,1],"10.1086/422312"],[16291984,"Sildenafil citrate therapy for pulmonary arterial hypertension.","N Engl J Med",2005,"Galiè et al.",2,[3,0],[20.55,16.74],26.92,17,14,12,[2,0,1,0,2,3,0,1,0,1,0,0,0,1,1,3],"10.1056/NEJMoa050010"],[16510744,"A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis.","N Engl J Med",2006,"Polman et al.",2,[5],[24.19],26.92,16,14,11,[1,1,4,2,0,0,1,1,1,1,1,0,0,1,1,0],"10.1056/NEJMoa044397"],[16714767,"Comparison of two fluid-management strategies in acute lung injury.","N Engl J Med",2006,"Wiedemann et al.",2,[3],[23.28],26.92,17,14,12,[1,0,2,2,0,2,1,0,1,2,0,1,0,0,3,0],"10.1056/NEJMoa062200"],[19217154,"Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial.","Lancet",2009,"Gottlieb et al.",2,[14,11,13],[26.92,13.81,13.81],26.92,17,14,13,[1,4,2,0,1,1,1,1,3,1,0,0,0,0,0,0],"10.1016/S0140-6736(09)60140-9"],[19632716,"Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial.","Lancet",2009,"Albain et al.",2,[1,3],[26.92,26.92],26.92,16,14,12,[0,1,4,1,3,0,1,0,0,1,0,1,2,0,2,0],"10.1016/S0140-6736(09)60737-6"],[19920054,"Ferric carboxymaltose in patients with heart failure and iron deficiency.","N Engl J Med",2009,"Anker et al.",2,[7,0,10],[8.47,15.97,16.6],26.92,24,14,11,[1,2,2,0,2,1,2,1,0,0,1,1,0,0,1,2],"10.1056/NEJMoa0908355"],[20888993,"Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial.","Lancet",2010,"Rustin et al.",2,[1,9,7],[26.92,24.82,20.05],26.92,14,14,11,[0,1,1,1,0,0,0,2,3,1,0,0,1,2,0,2],"10.1016/S0140-6736(10)61268-8"],[21782772,"Increased perioperative mortality following bariatric surgery among patients with cirrhosis.","Clin Gastroenterol Hepatol",2011,"Mosko et al.",7,[7],[9.48],26.92,20,14,16,[0,0,1,0,1,0,0,1,1,1,1,2,0,2,5,0],"10.1016/j.cgh.2011.07.007"],[22784037,"Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.","N Engl J Med",2012,"Baeten et al.",2,[2,9,12],[26.92,26.92,22.72],26.92,14,14,11,[0,0,1,1,1,2,2,1,2,0,1,1,0,1,1,0],"10.1056/NEJMoa1108524"],[23071237,"Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.","J Clin Oncol",2013,"van den Bent et al.",2,[1,5],[26.92,26.92],26.92,16,14,12,[0,0,2,2,2,1,2,2,0,0,1,2,0,0,2,0],"10.1200/JCO.2012.43.2229"],[23071247,"Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402.","J Clin Oncol",2013,"Cairncross et al.",2,[1,5],[26.92,26.92],26.92,16,14,12,[0,0,2,2,3,1,2,1,0,0,1,2,0,0,2,0],"10.1200/JCO.2012.43.2674"],[26735990,"Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia.","N Engl J Med",2016,"Zeisler et al.",5,[9],[22.09],26.92,16,14,12,[0,0,0,0,0,1,1,2,0,3,0,1,1,1,2,2],"10.1056/NEJMoa1414838"],[19907042,"Revascularization versus medical therapy for renal-artery stenosis.","N Engl J Med",2009,"Wheatley et al.",2,[0,8],[26.91,2.69],26.91,21,14,11,[2,2,2,0,0,1,1,1,1,1,1,0,0,2,1,1],"10.1056/NEJMoa0905368"],[10072411,"Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group.","N Engl J Med",1999,"Walsh et al.",2,[2,10],[23.03,8.08],26.82,20,18,12,[6,3,3,2,0,2,0,0,2,0,0,0,0,0,0,0],"10.1056/NEJM199903113401004"],[20171502,"Use of normal tissue complication probability models in the clinic.","Int J Radiat Oncol Biol Phys",2010,"Marks et al.",7,[13],[8.47],26.81,18,15,11,[0,1,0,2,2,1,1,2,0,0,0,4,0,1,1,2],"10.1016/j.ijrobp.2009.07.1754"],[26909664,"Consensus definition of fetal growth restriction: a Delphi procedure.","Ultrasound Obstet Gynecol",2016,"Gordijn et al.",4,[9,17],[24.77,17.81],26.81,16,15,12,[0,0,0,0,0,0,1,0,1,2,0,1,1,4,3,2],"10.1002/uog.15884"],[27717298,"Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy.","N Engl J Med",2016,"Eggermont et al.",2,[1,14],[26.81,19.85],26.81,18,15,12,[0,0,0,0,0,0,1,1,5,5,2,1,1,0,2,0],"10.1056/NEJMoa1611299"],[34491661,"Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension.","N Engl J Med",2021,"Zhang et al.",2,[0],[24.41],26.8,27,19,15,[0,0,0,0,0,0,0,0,0,0,0,0,3,8,6,4],"10.1056/NEJMoa2111437"],[9036306,"The effect of digoxin on mortality and morbidity in patients with heart failure.","N Engl J Med",1997,"Digitalis Investigation Group",2,[0],[26.76],26.76,27,18,9,[1,2,3,3,0,4,1,0,1,0,2,0,1,0,2,0],"10.1056/NEJM199702203360801"],[16080087,"Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans.","Clin Infect Dis",2005,"Ostrosky-Zeichner et al.",7,[2],[24.78],26.75,19,16,13,[5,2,3,2,2,1,0,0,0,0,0,0,1,0,0,0],"10.1086/432470"],[8801446,"The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. 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al.",2,[7,9],[22.44,14.06],26.05,16,13,12,[0,0,2,0,3,0,1,3,0,3,1,1,0,1,1,0],"10.1056/NEJMoa0707193"],[18753647,"Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma.","N Engl J Med",2008,"San Miguel et al.",2,[1,10,0],[26.05,23.28,21.24],26.05,15,13,12,[3,1,3,1,1,0,1,0,1,0,2,2,0,0,0,0],"10.1056/NEJMoa0801479"],[19339720,"Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.","N Engl J Med",2009,"Van Cutsem et al.",2,[1,4],[26.05,26.05],26.05,22,14,10,[2,3,0,4,1,1,1,2,2,1,1,0,2,1,1,0],"10.1056/NEJMoa0805019"],[19553646,"Routine early angioplasty after fibrinolysis for acute myocardial infarction.","N Engl J Med",2009,"Cantor et al.",2,[0],[26.05],26.05,26,16,9,[2,3,2,1,2,1,2,1,1,1,0,1,0,1,1,0],"10.1056/NEJMoa0808276"],[19641201,"Perioperative safety in the longitudinal assessment of bariatric surgery.","N Engl J Med",2009,"Flum et al.",5,[7],[21.86],26.05,21,13,14,[3,2,1,1,0,0,3,0,1,2,1,1,0,0,0,0],"10.1056/NEJMoa0901836"],[19758692,"Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study.","Lancet",2009,"Kuppermann et al.",5,[13,5],[18.57,16.6],26.05,18,13,13,[0,1,0,2,0,1,0,2,0,2,1,1,0,2,0,2],"10.1016/S0140-6736(09)61558-0"],[20409751,"Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial.","Lancet Oncol",2010,"Songun et al.",2,[1,4],[26.05,26.05],26.05,14,13,12,[2,2,4,1,0,0,0,1,0,1,0,0,0,1,1,1],"10.1016/S1470-2045(10)70070-X"],[21997563,"Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS).","Gut",2012,"Travis et al.",7,[4],[23.28],26.05,16,13,13,[0,1,1,0,0,0,1,3,1,0,1,0,1,3,4,0],"10.1136/gutjnl-2011-300486"],[22095893,"Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials.","Hepatology",2012,"Bernardi et al.",0,[4],[23.28],26.05,13,13,12,[0,0,0,0,1,2,1,3,1,1,1,0,0,2,1,0],"10.1002/hep.24786"],[23764209,"Frailty consensus: a call to action.","J Am Med Dir Assoc",2013,"Morley et al.",4,[7],[9.77],26.05,14,13,13,[0,0,1,1,1,2,1,0,4,0,1,1,1,0,0,0],"10.1016/j.jamda.2013.03.022"],[24245566,"Stenting and medical therapy for atherosclerotic renal-artery stenosis.","N Engl J Med",2014,"Cooper et al.",2,[0,8],[26.05,3.1],26.05,20,15,11,[0,0,0,0,0,1,3,3,2,1,1,0,0,2,2,2],"10.1056/NEJMoa1310753"],[26144908,"Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial.","Lancet",2015,"Leder et al.",2,[13,7],[26.05,23.95],26.05,17,13,12,[0,0,0,0,0,1,1,0,2,4,0,2,2,1,1,1],"10.1016/S0140-6736(15)61120-5"],[29107679,"Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial.","Lancet Oncol",2017,"Vilgrain et al.",2,[1,4],[26.05,26.05],26.05,18,13,14,[0,0,0,0,0,0,0,2,1,1,3,3,1,3,1,1],"10.1016/S1470-2045(17)30683-6"],[15131789,"Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity.","Gastroenterology",2004,"Chalasani et al.",5,[7],[5.78],26.01,21,13,11,[0,1,1,1,0,1,0,2,3,1,2,0,1,2,0,1],"10.1053/j.gastro.2004.02.015"],[15531767,"Angiotensin-converting-enzyme inhibition in stable coronary artery disease.","N Engl J Med",2004,"Braunwald et al.",2,[0],[26.01],26.01,40,19,9,[4,5,4,2,3,0,0,1,1,2,0,0,1,1,0,2],"10.1056/NEJMoa042739"],[15842354,"Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients.","J Thromb Haemost",2005,"Schulman et al.",7,[0],[21.61],26.01,16,15,10,[1,1,2,1,0,0,1,1,3,0,1,0,1,2,0,1],"10.1111/j.1538-7836.2005.01204.x"],[16020800,"Derivation and validation of a prognostic model for pulmonary embolism.","Am J Respir Crit Care Med",2005,"Aujesky et al.",7,[0,3],[26.01,18.53],26.01,15,13,11,[2,1,2,1,1,1,0,1,1,2,2,0,0,0,1,0],"10.1164/rccm.200506-862OC"],[18997198,"Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial.","JAMA",2008,"Ogawa et al.",2,[0,7],[23.81,14.28],26.01,20,13,12,[3,1,2,3,1,1,1,1,1,0,2,0,0,2,0,0],"10.1001/jama.2008.623"],[20619634,"Sequential adjuvant chemotherapy and radiotherapy in endometrial cancer--results from two randomised studies.","Eur J Cancer",2010,"Hogberg et al.",2,[1,9],[26.01,26.01],26.01,19,13,11,[0,1,1,4,1,1,3,1,0,0,1,1,2,0,2,0],"10.1016/j.ejca.2010.06.002"],[21991949,"Adjuvant trastuzumab in HER2-positive breast cancer.","N Engl J Med",2011,"Slamon et al.",2,[1],[22.4],26.01,16,13,11,[0,1,2,1,2,2,1,0,1,1,0,0,1,2,0,2],"10.1056/NEJMoa0910383"],[23770005,"Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis.","Gastroenterology",2014,"Sandborn et al.",2,[4],[26.01],26.01,16,13,12,[0,0,0,0,1,1,2,1,1,1,1,1,2,2,3,0],"10.1053/j.gastro.2013.06.010"],[24618336,"Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.","Lancet Oncol",2014,"Judson et al.",2,[1],[26.01],26.01,15,13,11,[0,0,0,1,1,1,1,1,0,0,2,1,1,2,3,1],"10.1016/S1470-2045(14)70063-4"],[33301740,"Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial.","Lancet Oncol",2021,"Bahadoer et al.",2,[1,4],[26.01,26.01],26.01,15,15,14,[0,0,0,0,0,0,0,0,0,0,0,2,1,5,5,2],"10.1016/S1470-2045(20)30555-6"],[33501848,"Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart 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al.",2,[0],[25.69],25.69,20,14,11,[0,4,2,0,1,2,0,0,2,1,0,1,0,1,1,0],"10.1056/NEJMoa0909938"],[20039396,"Humoral responses after influenza vaccination are severely reduced in patients with rheumatoid arthritis treated with rituximab.","Arthritis Rheum",2010,"van Assen et al.",7,[11],[21.24],25.69,15,14,12,[3,1,1,1,1,2,0,0,0,0,2,0,0,1,0,2],"10.1002/art.25033"],[20061358,"The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study.","BMJ",2010,"Bonds et al.",2,[7,0],[25.69,7.97],25.69,16,14,11,[0,3,5,1,1,1,0,0,0,1,0,1,2,1,0,0],"10.1136/bmj.b4909"],[21121834,"Body-mass index and mortality among 1.46 million white adults.","N Engl J Med",2010,"Berrington de Gonzalez et al.",7,[7],[15.45],25.69,24,14,15,[1,2,3,2,1,3,0,0,1,1,0,0,0,1,0,0],"10.1056/NEJMoa1000367"],[21944678,"Type-selective benefits of medications in treatment of acute aortic dissection (from the International Registry of Acute Aortic 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Postmenopausal Women with Osteoporosis.","N Engl J Med",2016,"Cosman et al.",2,[13,7],[25.65,23.15],25.65,17,15,12,[0,0,0,0,0,0,0,0,1,3,0,3,1,4,3,1],"10.1056/NEJMoa1607948"],[29386200,"Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association.","Circulation",2018,"Benjamin et al.",6,[0,5],[25.65,6.2],25.65,15,15,12,[0,0,0,0,0,0,0,3,5,1,0,3,1,1,1,0],"10.1161/CIR.0000000000000558"],[22633653,"Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: risk-adjusted retrospective data analysis.","J Am Coll Cardiol",2012,"Smith et al.",2,[0],[25.63],25.63,20,16,10,[0,0,1,1,1,1,0,5,1,0,1,1,1,2,1,0],"10.1016/j.jacc.2012.03.030"],[12759479,"A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema.","N Engl J Med",2003,"Fishman et al.",2,[3],[25.62],25.62,15,15,11,[1,1,4,2,0,0,2,0,0,1,2,2,0,0,0,0],"10.1056/NEJMoa030287"],[26764059,"Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease: Cochrane Systematic Review and Meta-Analysis.","J Am Coll Cardiol",2016,"Anderson et al.",0,[0],[22.74],25.62,23,17,9,[0,0,0,0,0,2,0,2,4,3,0,1,1,3,3,0],"10.1016/j.jacc.2015.10.044"],[29552975,"MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis.","N Engl J Med",2018,"Kasivisvanathan et al.",2,[1,8,9],[25.62,25.62,25.62],25.62,18,15,11,[0,0,0,0,0,0,0,2,3,2,1,2,2,4,0,2],"10.1056/NEJMoa1801993"],[9366579,"A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group.","N Engl J Med",1997,"Cardo et al.",5,[2,9,12],[25.6,25.6,20.25],25.6,14,12,10,[0,2,2,1,1,1,1,1,1,1,1,1,0,0,1,0],"10.1056/NEJM199711203372101"],[24355639,"Updated clinical classification of pulmonary hypertension.","J Am Coll Cardiol",2013,"Simonneau et al.",6,[0,3],[23.63,18.57],25.6,22,16,11,[0,0,0,2,4,2,4,0,3,2,0,2,0,0,0,0],"10.1016/j.jacc.2013.10.029"],[12324552,"Warfarin, aspirin, or both after myocardial infarction.","N Engl J Med",2002,"Hurlen et al.",2,[0],[23.42],25.57,29,18,9,[6,2,5,2,1,1,0,1,0,3,0,0,1,1,0,0],"10.1056/NEJMoa020496"],[12736279,"Risk stratification in the long-QT syndrome.","N Engl J Med",2003,"Priori et al.",7,[0,17],[25.55,1.0],25.55,19,15,10,[0,1,4,1,1,1,2,1,2,0,1,0,0,1,0,0],"10.1056/NEJMoa022147"],[15723973,"Worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation.","Circulation",2005,"Cappato et al.",7,[0],[25.55],25.55,18,15,10,[3,2,4,1,1,0,0,1,1,1,0,1,0,1,0,0],"10.1161/01.CIR.0000157153.30978.67"],[25456757,"Aggressive risk factor reduction study for atrial fibrillation and implications for the outcome of ablation: the ARREST-AF cohort study.","J Am Coll Cardiol",2014,"Pathak et al.",5,[0],[25.55],25.55,25,15,10,[0,1,0,0,0,2,2,2,1,3,1,1,0,5,0,1],"10.1016/j.jacc.2014.09.028"],[15928285,"Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial.","JAMA",2005,"Wazni et al.",2,[0],[25.53],25.53,30,16,9,[2,3,2,2,0,2,1,2,0,1,0,1,0,3,1,0],"10.1001/jama.293.21.2634"],[18463377,"Sudden cardiac arrest associated with early repolarization.","N Engl J Med",2008,"Haïssaguerre et al.",5,[0],[25.53],25.53,21,16,9,[2,1,3,0,1,2,1,0,1,1,1,1,0,2,0,0],"10.1056/NEJMoa071968"],[22246443,"Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182 678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study.","Eur Heart J",2012,"Friberg et al.",5,[0,5],[25.52,15.45],25.52,25,16,11,[0,1,2,0,2,3,2,1,2,1,0,1,0,4,0,0],"10.1093/eurheartj/ehr488"],[20359842,"Long-term outcome of a routine versus selective invasive strategy in patients with non-ST-segment elevation acute coronary syndrome a meta-analysis of individual patient data.","J Am Coll Cardiol",2010,"Fox et al.",0,[0],[25.51],25.51,26,17,9,[3,4,2,3,1,1,2,1,1,0,0,1,0,2,1,0],"10.1016/j.jacc.2010.03.007"],[9196156,"Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.","J Clin Oncol",1997,"Burris et al.",2,[4,1,7],[25.49,24.82,22.72],25.49,15,14,11,[1,2,1,0,2,2,1,1,1,0,0,0,0,3,0,0],"10.1200/JCO.1997.15.6.2403"],[13679527,"A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome.","N Engl J Med",2003,"Crowther et al.",2,[0,11],[12.76,11.38],25.49,14,14,11,[3,2,1,1,0,2,0,0,0,1,2,0,1,1,0,0],"10.1056/NEJMoa035241"],[16196117,"Standardization of uveitis nomenclature for reporting clinical data. 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The Framingham Heart Study.","JAMA",1994,"Benjamin et al.",5,[0],[25.45],25.45,22,15,11,[2,1,2,2,0,1,1,1,0,0,1,0,0,4,1,0],""],[10896924,"Long term outcome after transjugular intrahepatic portosystemic stent-shunt in non-transplant cirrhotics with hepatorenal syndrome: a phase II study.","Gut",2000,"Brensing et al.",3,[4,8],[25.45,0.0],25.45,13,13,11,[0,1,1,0,0,0,1,2,1,1,1,0,0,2,2,1],"10.1136/gut.47.2.288"],[11677197,"A comparison of endoscopic ultrasound, magnetic resonance imaging, and exam under anesthesia for evaluation of Crohn's perianal fistulas.","Gastroenterology",2001,"Schwartz et al.",5,[4],[25.45],25.45,14,13,11,[1,0,1,3,2,1,0,1,1,1,0,0,0,0,2,1],"10.1053/gast.2001.28676"],[12393820,"Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.","N Engl J Med",2002,"Fisher et al.",7,[1],[25.45],25.45,17,13,13,[2,1,0,1,3,3,1,0,0,1,2,0,1,0,0,1],"10.1056/NEJMoa022152"],[12686036,"Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial.","Lancet",2003,"Sever et al.",2,[0,5],[21.83,5.08],25.45,27,17,10,[5,3,1,2,1,4,0,0,1,0,0,0,0,0,0,2],"10.1016/S0140-6736(03)12948-0"],[17227978,"Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial.","JAMA",2007,"Oettle et al.",2,[1,4,7],[25.45,25.45,25.45],25.45,14,13,11,[1,2,1,3,1,1,1,0,1,0,0,0,1,1,0,0],"10.1001/jama.297.3.267"],[18621047,"TIPS for Budd-Chiari syndrome: long-term results and prognostics factors in 124 patients.","Gastroenterology",2008,"Garcia-Pagán et al.",7,[4,0],[20.63,9.48],25.45,14,13,11,[1,1,1,1,0,2,1,0,0,1,1,0,0,3,0,2],"10.1053/j.gastro.2008.05.051"],[19070889,"Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study.","Lancet",2009,"Kitchener et al.",2,[1,9],[25.45,25.45],25.45,17,13,11,[0,2,1,2,0,0,3,1,0,2,1,1,2,0,0,1],"10.1016/S0140-6736(08)61766-3"],[19861671,"Risk of pancreatic cancer in families with Lynch syndrome.","JAMA",2009,"Kastrinos et al.",7,[1,4,7],[25.45,25.45,17.16],25.45,16,13,13,[0,0,4,1,1,1,1,1,1,1,0,1,0,0,0,1],"10.1001/jama.2009.1529"],[20818855,"Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.","N Engl J Med",2010,"Engert et al.",2,[1,10],[25.45,23.3],25.45,17,13,11,[2,1,1,5,1,0,2,2,0,0,0,1,0,1,0,1],"10.1056/NEJMoa1000067"],[21093036,"Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial.","Lancet",2010,"Esler et al.",2,[0],[25.45],25.45,18,15,10,[0,2,2,2,1,2,0,2,1,1,0,0,0,2,1,0],"10.1016/S0140-6736(10)62039-9"],[21723220,"Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis.","Gastroenterology",2011,"Colombel et al.",2,[4],[25.45],25.45,15,13,12,[0,1,1,0,3,0,2,1,2,0,1,0,1,1,2,0],"10.1053/j.gastro.2011.06.054"],[25392034,"Consensus on circulatory shock and hemodynamic monitoring. 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An evidence-based approach.","Arch Intern Med",2006,"Kaltenbach et al.",5,[4],[20.4],25.18,14,12,13,[1,0,0,1,1,3,1,1,0,0,0,2,1,2,0,0],"10.1001/archinte.166.9.965"],[18208849,"MR-IMPACT: comparison of perfusion-cardiac magnetic resonance with single-photon emission computed tomography for the detection of coronary artery disease in a multicentre, multivendor, randomized trial.","Eur Heart J",2008,"Schwitter et al.",2,[0],[25.18],25.18,21,14,12,[0,2,1,3,0,0,0,1,0,1,2,1,1,0,2,0],"10.1093/eurheartj/ehm617"],[18725614,"Identifying unprovoked thromboembolism patients at low risk for recurrence who can discontinue anticoagulant therapy.","CMAJ",2008,"Rodger et al.",2,[0],[25.18],25.18,12,12,12,[1,2,2,1,0,0,0,0,1,1,2,1,0,1,0,0],"10.1503/cmaj.080493"],[19320986,"The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis.","BMC Public Health",2009,"Guh et 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preventing the recurrence of venous thromboembolism.","N Engl J Med",2012,"Becattini et al.",2,[0],[24.97],24.97,17,14,11,[0,0,3,2,0,1,0,0,1,3,3,0,0,1,0,2],"10.1056/NEJMoa1114238"],[23075127,"Hydroxyethyl starch or saline for fluid resuscitation in intensive care.","N Engl J Med",2012,"Myburgh et al.",2,[8],[7.97],24.97,16,14,11,[0,0,3,1,3,2,1,1,0,2,0,1,0,0,0,0],"10.1056/NEJMoa1209759"],[12063368,"Cardiac resynchronization in chronic heart failure.","N Engl J Med",2002,"Abraham et al.",2,[0],[23.61],24.96,36,21,8,[0,4,6,3,0,0,0,0,3,2,1,1,2,0,0,0],"10.1056/NEJMoa013168"],[26466021,"Polymer-free Drug-Coated Coronary Stents in Patients at High Bleeding Risk.","N Engl J Med",2015,"Urban et al.",2,[0],[24.96],24.96,23,17,10,[0,0,0,0,0,2,2,4,1,1,2,2,0,4,0,0],"10.1056/NEJMoa1503943"],[31475794,"Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.","N Engl J Med",2019,"Solomon et 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rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks.","Arthritis Rheum",2006,"Cohen et al.",2,[11],[24.77],24.77,14,14,11,[4,2,1,0,2,2,1,0,0,0,0,0,0,0,1,1],"10.1002/art.22025"],[19818785,"Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease.","Gastroenterology",2010,"Baert et al.",5,[4],[24.77],24.77,15,14,11,[2,1,3,3,0,0,0,1,2,0,0,0,0,1,2,0],"10.1053/j.gastro.2009.09.056"],[25935570,"Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials.","J Acad Nutr Diet",2015,"Franz et al.",0,[7],[20.7],24.77,17,14,12,[0,0,0,0,0,1,0,2,0,2,2,3,1,2,0,1],"10.1016/j.jand.2015.02.031"],[27404185,"Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When 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fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie.","J Clin Oncol",2008,"Al-Batran et al.",2,[1,4],[24.72,24.72],24.72,17,13,10,[2,1,1,0,2,1,0,1,2,0,0,3,0,1,1,2],"10.1200/JCO.2007.13.9378"],[19091394,"Endocrine treatment, with or without radiotherapy, in locally advanced prostate cancer (SPCG-7/SFUO-3): an open randomised phase III trial.","Lancet",2009,"Widmark et al.",2,[1,8,9],[24.72,24.72,24.72],24.72,18,13,10,[1,1,3,3,1,0,2,1,0,2,0,1,0,1,0,1],"10.1016/S0140-6736(08)61815-2"],[20354937,"Peroral endoscopic myotomy (POEM) for esophageal achalasia.","Endoscopy",2010,"Inoue et al.",3,[4],[23.3],24.72,14,13,10,[0,1,1,0,0,1,1,2,0,3,1,0,1,1,1,1],"10.1055/s-0029-1244080"],[20660832,"Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era.","J Clin Oncol",2010,"Gisselbrecht et al.",2,[1,10],[24.72,24.72],24.72,14,13,10,[1,1,1,1,2,1,1,0,0,0,0,1,1,0,3,1],"10.1200/JCO.2010.28.1618"],[22995653,"Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study.","Lancet Oncol",2012,"Fizazi et al.",2,[1,8,9],[22.52,22.52,22.52],24.72,17,13,10,[0,0,0,1,1,2,0,0,2,1,1,1,2,2,3,1],"10.1016/S1470-2045(12)70379-0"],[12443589,"The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a randomised controlled trial.","Lancet",2002,"Ashton et al.",2,[0],[24.67],24.67,14,11,11,[2,0,1,1,1,1,1,1,2,0,1,0,1,1,0,1],"10.1016/s0140-6736(02)11522-4"],[17498584,"Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial.","J Am Coll Cardiol",2007,"Bhatt et al.",2,[0,5],[24.63,0.0],24.63,29,17,9,[3,2,2,1,0,2,1,4,0,1,1,0,0,1,0,0],"10.1016/j.jacc.2007.03.025"],[20172912,"Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria.","Eur Heart J",2010,"Marcus et al.",4,[0,17],[22.52,1.0],24.62,18,15,10,[0,0,0,3,2,1,2,0,0,2,2,1,0,2,1,0],"10.1093/eurheartj/ehq025"],[21428765,"Tiotropium versus salmeterol for the prevention of exacerbations of COPD.","N Engl J Med",2011,"Vogelmeier et al.",2,[3],[24.62],24.62,15,13,12,[1,2,2,0,0,1,4,0,0,0,1,1,0,0,1,1],"10.1056/NEJMoa1008378"],[24240712,"Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial.","JAMA",2014,"Kim et al.",2,[0],[21.89],24.62,19,15,10,[0,0,0,0,7,1,1,2,0,1,1,1,0,0,3,1],"10.1001/jama.2013.282173"],[29420164,"Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer.","N Engl J Med",2018,"Smith et al.",2,[1,8,9],[24.62,24.62,24.62],24.62,19,13,11,[0,0,0,0,0,0,0,1,2,3,3,2,2,3,1,2],"10.1056/NEJMoa1715546"],[29949494,"Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer.","N Engl J Med",2018,"Hussain et al.",2,[1,8,9],[24.62,24.62,24.62],24.62,19,13,11,[0,0,0,0,0,0,0,1,2,3,3,2,2,3,1,2],"10.1056/NEJMoa1800536"],[21697170,"Comparison of coronary bypass surgery with drug-eluting stenting for the treatment of left main and/or three-vessel disease: 3-year follow-up of the SYNTAX trial.","Eur Heart J",2011,"Kappetein et al.",2,[0],[22.64],24.61,30,18,10,[2,5,5,5,5,1,0,0,0,0,0,0,0,1,0,0],"10.1093/eurheartj/ehr213"],[24024839,"Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer.","N Engl J Med",2013,"Douillard et al.",2,[1,4],[24.61,22.09],24.61,22,16,11,[0,0,0,4,2,1,3,1,0,0,2,0,2,4,0,0],"10.1056/NEJMoa1305275"],[28578601,"Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation.","N Engl J Med",2017,"Robson et al.",2,[1],[24.6],24.6,17,16,11,[0,0,0,0,0,0,0,1,0,4,3,3,0,3,0,3],"10.1056/NEJMoa1706450"],[11807147,"CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma.","N Engl J Med",2002,"Coiffier et al.",2,[1,10],[24.56,20.94],24.56,14,14,10,[2,2,2,2,1,1,0,1,1,0,0,0,0,1,1,0],"10.1056/NEJMoa011795"],[15007010,"Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: a randomized trial.","Circulation",2004,"Hambrecht et al.",2,[0],[24.56],24.56,26,18,11,[5,2,2,2,1,2,0,1,0,0,0,2,1,1,0,0],"10.1161/01.CIR.0000121360.31954.1F"],[15175845,"Smoking and fracture risk: a meta-analysis.","Osteoporos Int",2005,"Kanis et al.",0,[13],[24.56],24.56,16,12,11,[0,1,2,0,0,1,0,1,2,1,3,2,0,1,1,0],"10.1007/s00198-004-1640-3"],[17470865,"Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria.","J Clin Oncol",2007,"Choi et al.",7,[1,4],[24.56,18.89],24.56,15,12,11,[0,2,2,1,2,1,1,1,0,0,0,1,0,1,3,0],"10.1200/JCO.2006.07.3049"],[17620458,"Radiation exposure and pregnancy: when should we be concerned?","Radiographics",2007,"McCollough et al.",6,[9,13,17],[17.16,7.97,0.0],24.56,14,12,11,[2,1,1,0,1,2,0,0,0,1,0,1,1,1,0,1],"10.1148/rg.274065149"],[17720017,"Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis.","Lancet",2007,"Tang et al.",0,[13,7],[15.56,13.81],24.56,14,12,11,[2,0,2,1,0,0,1,1,2,1,0,1,0,1,2,0],"10.1016/S0140-6736(07)61342-7"],[18177818,"Gastroenteropancreatic neuroendocrine tumours.","Lancet Oncol",2008,"Modlin et al.",6,[1,4,7],[24.56,19.2,14.63],24.56,12,12,11,[1,1,1,1,3,1,1,0,0,0,1,0,0,0,1,1],"10.1016/S1470-2045(07)70410-2"],[19901110,"NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.","J Clin Oncol",2009,"Wick et al.",2,[1,5],[24.56,24.56],24.56,14,12,11,[2,1,1,2,1,1,2,0,0,0,0,2,0,0,1,1],"10.1200/JCO.2009.23.6497"],[20581422,"A randomized, controlled trial of early versus late initiation of dialysis.","N Engl J Med",2010,"Cooper et al.",2,[8],[21.86],24.56,13,12,12,[0,0,0,2,3,0,1,0,1,1,1,1,1,1,1,0],"10.1056/NEJMoa1000552"],[21039302,"Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity.","Ann Med",2011,"Musso et al.",0,[4],[19.76],24.56,15,12,11,[0,2,1,1,2,1,0,1,2,0,1,1,0,1,0,0],"10.3109/07853890.2010.518623"],[21444835,"Clinical features of 8295 patients with resistant hypertension classified on the basis of ambulatory blood pressure monitoring.","Hypertension",2011,"de la Sierra et al.",7,[0],[24.56],24.56,16,12,11,[0,1,1,0,0,1,1,2,3,1,0,0,0,1,1,2],"10.1161/HYPERTENSIONAHA.110.168948"],[21699794,"FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease.","Gastroenterology",2011,"Evstatiev et al.",2,[4,10,7],[19.2,11.38,7.58],24.56,15,12,11,[0,0,1,0,1,1,0,1,0,1,1,1,2,4,2,0],"10.1053/j.gastro.2011.06.005"],[23280227,"Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis.","JAMA",2013,"Flegal et al.",0,[7],[18.1],24.56,17,12,11,[0,0,2,2,1,2,1,1,2,0,0,2,0,0,1,1],"10.1001/jama.2012.113905"],[24836312,"A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.","N Engl J Med",2014,"King et al.",2,[3],[24.56],24.56,18,12,12,[0,0,0,0,2,2,3,1,0,1,1,2,2,1,1,0],"10.1056/NEJMoa1402582"],[26412456,"Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.","N Engl J Med",2015,"Borghaei et al.",2,[1,3],[24.56,18.01],24.56,20,14,13,[0,0,0,0,0,0,3,3,2,2,1,1,2,2,1,1],"10.1056/NEJMoa1507643"],[17046465,"Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial.","Lancet",2006,"Demetri et al.",2,[1,4],[24.51,18.1],24.51,16,13,10,[0,2,2,2,0,1,1,1,1,0,0,1,1,2,2,0],"10.1016/S0140-6736(06)69446-4"],[17368233,"Incidence of Clostridium difficile infection in inflammatory bowel disease.","Clin Gastroenterol Hepatol",2007,"Rodemann et al.",5,[4,2],[21.83,2.69],24.51,16,13,10,[2,1,1,2,0,1,1,2,0,0,0,0,1,2,2,1],"10.1016/j.cgh.2006.12.027"],[17609301,"Ultrasound criteria of malignancy for cervical lymph nodes in patients followed up for differentiated thyroid cancer.","J Clin Endocrinol Metab",2007,"Leboulleux et al.",3,[1,7],[20.42,24.51],24.51,15,13,10,[1,1,1,0,2,1,0,0,1,1,1,1,2,0,2,0],"10.1210/jc.2007-0444"],[16052578,"Decreased incidence of anterior uveitis in patients with ankylosing spondylitis treated with the anti-tumor necrosis factor agents infliximab and etanercept.","Arthritis Rheum",2005,"Braun et al.",6,[11,13,15],[24.49,17.76,1.0],24.49,15,13,12,[3,0,1,2,0,0,2,1,3,0,0,0,2,0,0,0],"10.1002/art.21197"],[20008689,"Projected cancer risks from computed tomographic scans performed in the United States in 2007.","Arch Intern Med",2009,"Berrington de González et al.",7,[1,13],[9.02,6.2],24.49,15,13,12,[2,2,3,1,0,0,3,0,0,0,1,1,0,0,0,0],"10.1001/archinternmed.2009.440"],[22851115,"Prevalence and phenotypes of APC and MUTYH mutations in patients with multiple colorectal adenomas.","JAMA",2012,"Grover et al.",5,[1,4,17],[24.49,22.52,12.63],24.49,13,13,12,[0,0,1,0,2,0,0,0,1,3,0,0,0,3,1,2],"10.1001/jama.2012.8780"],[24645800,"Multitarget stool DNA testing for colorectal-cancer screening.","N Engl J Med",2014,"Imperiale et al.",3,[1,4],[22.52,24.49],24.49,19,13,12,[0,0,0,0,1,4,3,0,0,0,2,0,1,0,2,1],"10.1056/NEJMoa1311194"],[25007392,"Secukinumab in plaque psoriasis--results of two phase 3 trials.","N Engl J Med",2014,"Langley et al.",2,[14],[20.55],24.49,14,13,12,[0,0,0,0,0,1,2,1,6,1,0,1,0,0,1,0],"10.1056/NEJMoa1314258"],[25071125,"International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer.","J Clin Oncol",2014,"Wildiers et al.",4,[1],[19.74],24.49,14,13,12,[0,0,0,0,0,0,1,2,2,1,4,0,0,0,1,2],"10.1200/JCO.2013.54.8347"],[25956718,"Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): a pragmatic, open-label, cluster randomised feasibility trial.","Lancet",2015,"Jairath et al.",2,[4],[11.85],24.49,14,13,12,[0,0,0,0,0,2,0,0,3,2,2,1,1,0,3,0],"10.1016/S0140-6736(14)61999-1"],[27717299,"Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer.","N Engl J Med",2016,"Mirza et al.",2,[1,7,9],[24.49,18.63,18.63],24.49,16,15,11,[0,0,0,0,0,0,0,2,2,3,1,0,0,5,1,2],"10.1056/NEJMoa1611310"],[28789921,"Discontinuation of Denosumab therapy for osteoporosis: A systematic review and position statement by ECTS.","Bone",2017,"Tsourdi et al.",1,[13,7],[22.52,16.99],24.49,17,13,12,[0,0,0,0,0,0,0,0,4,2,2,2,0,1,3,1],"10.1016/j.bone.2017.08.003"],[28889792,"Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.","N Engl J Med",2017,"Wolchok et al.",2,[1,14],[22.52,15.17],24.49,18,13,12,[0,0,0,0,0,0,0,1,5,2,2,2,2,0,3,0],"10.1056/NEJMoa1709684"],[30355464,"Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.","Lancet",2018,"Parker et al.",2,[1,8,9],[24.49,23.96,23.34],24.49,20,15,11,[0,0,0,0,0,0,0,0,1,3,3,4,0,5,2,2],"10.1016/S0140-6736(18)32486-3"],[32053298,"Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis.","N Engl J Med",2020,"Walsh et al.",2,[0,11,14],[19.74,19.74,16.99],24.49,16,13,11,[0,0,0,0,0,0,0,0,0,1,2,1,3,3,4,1],"10.1056/NEJMoa1803537"],[11096167,"The effect of fecal occult-blood screening on the 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trial.","Lancet",2007,"Eriksson et al.",2,[0],[24.48],24.48,13,12,12,[2,3,2,0,1,0,1,2,0,0,0,0,0,1,0,1],"10.1016/S0140-6736(07)61445-7"],[18477802,"Design and endpoints of clinical trials in hepatocellular carcinoma.","J Natl Cancer Inst",2008,"Llovet et al.",6,[1,4],[24.48,24.48],24.48,18,12,14,[0,2,0,1,3,3,1,0,1,0,2,1,0,0,0,0],"10.1093/jnci/djn134"],[19109574,"Azathioprine or methotrexate maintenance for ANCA-associated vasculitis.","N Engl J Med",2008,"Pagnoux et al.",2,[0,11,14],[22.44,22.44,22.44],24.48,14,12,12,[2,0,0,0,1,0,0,0,1,1,2,0,1,2,3,0],"10.1056/NEJMoa0802311"],[21482652,"Corticosteroid use during pregnancy and risk of orofacial clefts.","CMAJ",2011,"Hviid et al.",5,[17,16,13],[1.0,0.0,0.0],24.48,12,12,12,[0,0,0,0,1,1,0,0,2,0,1,0,2,3,1,1],"10.1503/cmaj.101063"],[22286927,"CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT.","Thorax",2012,"Saghir et al.",2,[1,3],[24.48,24.48],24.48,15,12,12,[0,0,2,2,3,1,1,3,0,0,1,0,1,0,0,0],"10.1136/thoraxjnl-2011-200736"],[22416101,"Endoscopic transgastric vs surgical necrosectomy for infected necrotizing pancreatitis: a randomized trial.","JAMA",2012,"Bakker et al.",2,[4],[24.48],24.48,13,12,12,[0,0,2,0,2,2,1,0,0,0,0,1,0,2,1,2],"10.1001/jama.2012.276"],[23321763,"Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a randomized controlled trial.","JAMA",2013,"Reignier et al.",2,[2,3],[15.78,4.04],24.48,15,12,13,[0,0,0,4,0,2,2,0,1,1,1,0,1,0,2,0],"10.1001/jama.2012.196377"],[26247167,"Efficacy of Proton Pump Inhibitor Drugs for Inducing Clinical and Histologic Remission in Patients With Symptomatic Esophageal Eosinophilia: A Systematic Review and 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Intergroupe Français du Myélome.","N Engl J Med",1996,"Attal et al.",2,[1,10,0],[24.19,22.03,21.14],24.19,17,13,10,[2,0,3,2,2,0,1,0,1,2,1,1,0,0,0,2],"10.1056/NEJM199607113350204"],[14519707,"Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial.","JAMA",2003,"Cauley et al.",2,[13],[21.51],24.19,17,11,11,[0,1,2,0,0,1,3,1,2,1,1,2,0,1,1,0],"10.1001/jama.290.13.1729"],[15983291,"Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: results of prospectively designed overviews of randomized trials.","Arch Intern Med",2005,"Turnbull et al.",0,[0,7],[19.39,6.16],24.19,24,13,12,[2,3,2,2,0,1,0,1,1,0,1,0,1,1,0,0],"10.1001/archinte.165.12.1410"],[17179057,"Complications of colonoscopy in an integrated health care delivery system.","Ann Intern Med",2006,"Levin et 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Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group.","Arch Ophthalmol",1985,"",2,[7,15,0],[20.4,17.16,15.78],23.95,17,12,11,[2,2,1,3,2,2,2,0,0,0,0,0,0,1,1,0],""],[8823332,"Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study.","J Clin Oncol",1996,"Flam et al.",2,[1,4],[23.95,23.95],23.95,16,12,11,[0,1,0,2,0,0,2,2,0,0,2,0,1,1,2,1],"10.1200/JCO.1996.14.9.2527"],[11108925,"Pregnancy and medical radiation.","Ann ICRP",2000,"International Commission on Radiological",7,[9,1],[12.65,9.02],23.95,14,12,11,[1,1,0,0,1,2,0,0,0,0,1,1,0,1,2,3],"10.1016/s0146-6453(00)00037-3"],[12493258,"HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS).","Lancet",2002,"Thio et 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Group",2,[9,1,2],[18.01,17.16,10.83],23.95,15,14,11,[1,3,3,1,0,1,2,0,1,0,0,0,1,0,1,0],"10.1056/NEJMoa061741"],[17555418,"Meta-analysis: the efficacy of rectal beclomethasone dipropionate vs. 5-aminosalicylic acid in mild to moderate distal ulcerative colitis.","Aliment Pharmacol Ther",2007,"Manguso et al.",0,[4],[23.95],23.95,14,12,11,[2,1,1,0,2,0,2,2,0,1,0,0,2,1,0,0],"10.1111/j.1365-2036.2007.03349.x"],[18355913,"The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial.","Lancet",2008,"Bentzen et al.",2,[1],[23.95],23.95,20,12,13,[4,2,2,2,3,2,1,2,1,0,0,0,0,0,0,0],"10.1016/S0140-6736(08)60348-7"],[18718471,"Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis.","Gastroenterology",2008,"Aithal et al.",2,[4],[21.24],23.95,18,12,13,[0,2,1,0,1,1,0,1,0,0,3,2,0,1,0,1],"10.1053/j.gastro.2008.06.047"],[19502545,"International Expert Committee 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al.",5,[1,4],[18.36,21.24],23.95,16,12,12,[0,0,0,0,0,1,1,1,1,0,1,1,1,5,2,0],"10.1002/hep.27752"],[7723155,"Endarterectomy for asymptomatic carotid artery stenosis. 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Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico.","Lancet",1999,"",2,[0],[16.83],23.44,21,15,10,[1,6,3,0,1,1,1,0,2,0,0,0,0,0,0,0],""],[19481012,"INTERMACS profiles of advanced heart failure: the current picture.","J Heart Lung Transplant",2009,"Stevenson et al.",7,[0],[23.43],23.43,17,13,9,[0,1,3,0,0,0,1,0,2,1,1,1,1,1,1,1],"10.1016/j.healun.2009.02.015"],[24106937,"Diagnostic criteria for nonviable pregnancy early in the first trimester.","N Engl J Med",2013,"Doubilet et al.",6,[9],[21.61],23.42,20,16,11,[0,0,0,0,1,7,0,5,0,0,0,0,0,1,4,0],"10.1056/NEJMra1302417"],[19625712,"Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection.","N Engl J Med",2009,"McHutchison et al.",2,[2,4],[23.41,23.41],23.41,16,15,13,[2,8,1,5,0,0,0,0,0,0,0,0,0,0,0,0],"10.1056/NEJMoa0808010"],[32484754,"Stereotactic Ablative Radiotherapy for the Comprehensive Treatment of Oligometastatic Cancers: Long-Term Results of the SABR-COMET Phase II Randomized 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Findings from the RIETE Registry.","Thromb Haemost",2008,"Ruíz-Giménez et al.",2,[0],[22.4],23.3,15,14,9,[1,3,1,2,0,1,0,1,0,0,2,0,1,1,0,1],"10.1160/TH08-03-0193"],[19033573,"Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial.","J Natl Cancer Inst",2008,"Benedetti Panici et al.",2,[1,9],[23.3,23.3],23.3,15,12,10,[0,2,1,2,0,0,2,1,0,1,1,1,2,0,0,1],"10.1093/jnci/djn397"],[19470885,"Tadalafil therapy for pulmonary arterial hypertension.","Circulation",2009,"Galiè et al.",2,[3,0],[15.95,14.06],23.3,15,12,10,[2,0,1,0,2,2,0,1,1,1,0,0,0,1,1,2],"10.1161/CIRCULATIONAHA.108.839274"],[25399274,"Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation: a randomized clinical trial.","JAMA",2014,"Reddy et al.",2,[0,5],[23.3,9.02],23.3,21,12,10,[0,0,0,0,1,2,2,1,1,2,0,1,2,2,1,0],"10.1001/jama.2014.15192"],[26323946,"Systematic Review and Meta-analysis of Diagnostic Accuracy of Percutaneous Renal Tumour Biopsy.","Eur Urol",2016,"Marconi et al.",0,[1,8],[23.3,23.3],23.3,16,12,10,[0,0,0,0,0,2,2,2,2,2,1,2,1,1,1,0],"10.1016/j.eururo.2015.07.072"],[8644983,"The long-term clinical course of acute deep venous thrombosis.","Ann Intern Med",1996,"Prandoni et al.",5,[0,11],[23.28,0.0],23.28,13,12,11,[2,2,1,1,0,2,1,0,0,0,2,0,0,1,0,0],"10.7326/0003-4819-125-1-199607010-00001"],[9521222,"Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study.","Arch Intern Med",1998,"Silverstein et al.",5,[0,3],[23.28,4.65],23.28,12,12,11,[1,2,2,0,2,0,0,1,0,2,1,0,0,0,1,0],"10.1001/archinte.158.6.585"],[10493478,"Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases.","Ann Surg",1999,"Fong et al.",7,[1,4],[21.24,18.57],23.28,13,12,11,[0,0,3,0,0,1,1,1,0,0,1,0,1,2,2,0],"10.1097/00000658-199909000-00004"],[10580071,"Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant.","N Engl J Med",1999,"Wolfe et al.",5,[8],[11.58],23.28,12,12,11,[1,0,1,1,3,1,0,0,1,1,0,0,0,0,3,0],"10.1056/NEJM199912023412303"],[10714728,"Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). 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knee replacement: the RE-MODEL randomized trial.","J Thromb Haemost",2007,"Eriksson et al.",2,[0],[23.28],23.28,13,12,11,[1,2,2,0,1,0,1,4,1,0,0,0,0,0,0,1],"10.1111/j.1538-7836.2007.02748.x"],[18222442,"Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy.","Gastroenterology",2008,"Ghazale et al.",5,[4],[23.28],23.28,13,12,11,[0,2,0,1,4,0,1,0,2,1,0,1,0,0,0,1],"10.1053/j.gastro.2007.12.009"],[19136102,"The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research.","Gastrointest Endosc",2009,"Lai et al.",5,[4,1],[23.28,20.55],23.28,13,12,12,[0,3,0,2,1,1,0,1,0,0,1,2,0,0,1,0],"10.1016/j.gie.2008.05.057"],[19161179,"Corticosteroids but not infliximab increase short-term postoperative infectious complications in patients with ulcerative colitis.","Inflamm Bowel Dis",2009,"Ferrante et al.",7,[4,2],[21.24,1.0],23.28,13,12,11,[3,0,0,0,2,0,2,1,0,1,0,0,1,1,2,0],"10.1002/ibd.20863"],[19243769,"EUS-based criteria for the diagnosis of chronic pancreatitis: the Rosemont classification.","Gastrointest Endosc",2009,"Catalano et al.",7,[4],[23.28],23.28,12,12,11,[0,1,1,2,2,0,1,0,0,2,0,2,0,0,0,1],"10.1016/j.gie.2008.07.043"],[20029412,"Capsule endoscopy has a significantly higher diagnostic yield in patients with suspected and established small-bowel Crohn's disease: a meta-analysis.","Am J Gastroenterol",2010,"Dionisio et al.",0,[4],[23.28],23.28,13,12,11,[1,0,1,0,2,0,3,2,1,0,1,0,0,0,2,0],"10.1038/ajg.2009.713"],[21254162,"Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease.","Hepatology",2011,"Liaw et al.",2,[4,2],[21.24,20.4],23.28,16,12,11,[0,4,2,1,0,3,0,1,1,1,2,0,0,0,0,0],"10.1002/hep.23952"],[24269290,"Long-term efficacy and safety of endoscopic resection for patients with mucosal adenocarcinoma of the esophagus.","Gastroenterology",2014,"Pech et 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al.",2,[4],[23.28],23.28,12,12,11,[0,0,0,0,0,0,2,1,1,2,1,0,0,2,2,1],"10.1053/j.gastro.2015.05.011"],[27714755,"Peri-operative management of anticoagulation and antiplatelet therapy.","Br J Haematol",2016,"Keeling et al.",7,[0,4],[8.47,7.97],23.28,13,12,11,[0,0,0,0,0,0,0,1,2,1,2,1,0,2,2,1],"10.1111/bjh.14344"],[29875066,"Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial.","Lancet Oncol",2018,"Zhu et al.",3,[1,4],[23.28,21.24],23.28,15,12,11,[0,0,0,0,0,0,0,1,1,2,4,2,1,2,2,0],"10.1016/S1470-2045(18)30351-6"],[33933205,"Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis.","Lancet",2021,"Blood Pressure Lowering Treatment 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al.",6,[4,1],[23.22,15.12],23.22,17,13,9,[0,3,1,1,1,1,1,3,2,1,1,1,0,0,0,0],"10.1053/j.gastro.2004.09.014"],[19289638,"Safety of short-term discontinuation of antiplatelet therapy in patients with drug-eluting stents.","Circulation",2009,"Eisenberg et al.",5,[0],[11.84],23.22,17,13,9,[1,1,1,0,0,2,1,1,1,1,2,2,1,0,0,0],"10.1161/CIRCULATIONAHA.108.813667"],[21487090,"A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk.","Circ Cardiovasc Qual Outcomes",2011,"Sniderman et al.",0,[0],[15.0],23.22,21,13,9,[1,0,2,2,0,1,0,1,2,0,1,1,1,2,0,1],"10.1161/CIRCOUTCOMES.110.959247"],[6361299,"The Lipid Research Clinics Coronary Primary Prevention Trial results. 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Vertebral Efficacy with Risedronate Therapy (VERT) Study Group.","Osteoporos Int",2000,"Reginster et al.",2,[13,7],[23.01,22.31],23.01,16,13,9,[1,1,2,1,0,1,0,0,3,1,0,1,0,3,1,1],"10.1007/s001980050010"],[16325694,"Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trial.","Lancet",2005,"Adam et al.",2,[0],[22.42],23.01,27,17,7,[2,2,0,4,0,1,2,2,1,0,1,2,0,2,1,0],"10.1016/S0140-6736(05)67704-5"],[25542620,"Crohn's disease management after intestinal resection: a randomised trial.","Lancet",2015,"De Cruz et al.",2,[4],[22.98],22.98,15,14,12,[0,0,0,0,0,1,4,3,0,0,0,0,0,3,4,0],"10.1016/S0140-6736(14)61908-5"],[15939524,"Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data advanced bladder cancer (ABC) meta-analysis collaboration.","Eur Urol",2005,"Advanced Bladder Cancer (ABC) Meta-analy",0,[1,8],[22.97,22.97],22.97,16,12,10,[1,2,2,1,1,1,2,0,0,1,0,2,1,0,1,1],"10.1016/j.eururo.2005.04.006"],[2046107,"Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.","JAMA",1991,"",2,[0,5],[22.93,3.1],22.93,25,17,8,[3,2,4,3,3,2,1,0,1,0,0,0,0,0,0,0],""],[6735250,"Natural history of recurrent Crohn's disease at the ileocolonic anastomosis after curative surgery.","Gut",1984,"Rutgeerts et al.",7,[4],[22.93],22.93,13,13,10,[0,0,2,2,1,0,2,2,1,0,0,0,0,2,1,0],"10.1136/gut.25.6.665"],[10764420,"Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix.","J Clin Oncol",2000,"Peters et al.",2,[1,9],[22.93,22.93],22.93,15,13,10,[1,3,1,0,0,0,3,0,0,2,0,1,0,1,3,0],"10.1200/JCO.2000.18.8.1606"],[10841872,"A comparison of paracentesis and transjugular intrahepatic portosystemic shunting in patients with ascites.","N Engl J Med",2000,"Rössle et al.",2,[4,5,7],[22.93,0.0,0.0],22.93,13,13,10,[0,1,0,0,0,1,0,2,0,1,3,0,0,2,2,1],"10.1056/NEJM200006083422303"],[14625336,"Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial.","JAMA",2003,"Chastre et al.",2,[2,3],[22.93,11.58],22.93,16,13,10,[2,0,0,0,2,3,3,1,0,1,0,0,0,1,1,0],"10.1001/jama.290.19.2588"],[14702423,"Once-daily valacyclovir to reduce the risk of transmission of genital herpes.","N Engl J Med",2004,"Corey et al.",2,[2,9,8],[22.93,19.39,11.56],22.93,13,13,10,[1,0,2,0,1,1,3,0,0,0,1,0,0,0,3,1],"10.1056/NEJMoa035144"],[16336480,"Predicting aberrant behaviors in opioid-treated patients: preliminary validation of the Opioid Risk Tool.","Pain Med",2005,"Webster et al.",3,[6],[13.81],22.93,15,13,10,[1,2,2,2,0,3,1,0,0,0,0,1,2,0,0,0],"10.1111/j.1526-4637.2005.00072.x"],[16618396,"Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis.","Gastroenterology",2006,"Rutter et al.",7,[4,1],[22.09,11.56],22.93,16,13,12,[1,0,3,3,3,0,0,1,0,0,2,0,1,1,0,0],"10.1053/j.gastro.2005.12.035"],[16670137,"Meta-analysis: low-molecular-weight heparin and bleeding in patients with severe renal insufficiency.","Ann Intern Med",2006,"Lim et al.",0,[8],[0.0],22.93,15,13,10,[1,3,2,0,0,0,0,4,1,2,0,0,0,1,1,0],"10.7326/0003-4819-144-9-200605020-00011"],[23020162,"Trastuzumab emtansine for HER2-positive advanced breast cancer.","N Engl J Med",2012,"Verma et al.",2,[1],[22.93],22.93,16,13,9,[0,0,3,3,0,0,1,1,0,1,2,0,1,1,1,1],"10.1056/NEJMoa1209124"],[27634581,"Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non-masked, randomised controlled trial.","Lancet",2016,"Bolinder et al.",2,[7],[20.21],22.93,13,13,10,[0,0,0,0,0,0,0,2,2,1,2,1,2,2,0,1],"10.1016/S0140-6736(16)31535-5"],[29240541,"Surveillance or Metastasis-Directed Therapy for Oligometastatic Prostate Cancer Recurrence: A Prospective, Randomized, Multicenter Phase II Trial.","J Clin Oncol",2018,"Ost et al.",2,[1,8,9],[22.93,18.01,18.01],22.93,17,13,10,[0,0,0,0,0,0,0,1,0,4,1,2,1,5,2,1],"10.1200/JCO.2017.75.4853"],[8284001,"Risk factors for gastrointestinal bleeding in critically ill patients. Canadian Critical Care Trials Group.","N Engl J Med",1994,"Cook et al.",5,[4],[9.77],22.9,16,11,10,[1,0,1,1,0,1,2,1,1,1,0,0,1,2,1,0],"10.1056/NEJM199402103300601"],[15307872,"Treatment of rectal cuff inflammation (cuffitis) in patients with ulcerative colitis following restorative proctocolectomy and ileal pouch-anal anastomosis.","Am J Gastroenterol",2004,"Shen et al.",3,[4],[22.9],22.9,13,11,11,[1,1,1,1,1,0,1,2,0,1,0,0,1,1,2,0],"10.1111/j.1572-0241.2004.30518.x"],[17470858,"Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer.","J Clin Oncol",2007,"Van Cutsem et al.",2,[1,4],[20.7,17.91],22.9,21,13,9,[2,3,2,3,1,0,3,2,0,1,1,0,1,1,0,0],"10.1200/JCO.2006.08.1620"],[17968156,"The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma.","Ann Surg",2007,"Peeters et al.",2,[1,4],[22.9,22.9],22.9,18,11,10,[2,1,2,0,1,0,2,2,0,2,1,0,0,1,2,1],"10.1097/01.sla.0000257358.56863.ce"],[25908066,"Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug-Eluting Stent Implantation: The ISAR-TRIPLE Trial.","J Am Coll Cardiol",2015,"Fiedler et al.",2,[0],[22.9],22.9,21,17,8,[0,0,0,0,2,4,1,4,2,1,1,1,0,2,0,0],"10.1016/j.jacc.2015.02.050"],[27571048,"CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea.","N Engl J Med",2016,"McEvoy et al.",2,[5,3],[9.02,4.65],22.9,21,15,9,[0,0,0,0,0,0,1,4,1,2,1,1,1,2,1,2],"10.1056/NEJMoa1606599"],[12531577,"Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis.","Lancet",2003,"Rothwell et al.",0,[0,5],[22.83,18.05],22.83,22,14,9,[4,1,2,1,0,0,3,2,0,0,0,1,1,1,0,0],"10.1016/s0140-6736(03)12228-3"],[12837716,"Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic 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al.",7,[2,4],[22.75,22.75],22.75,13,12,12,[2,4,1,3,1,2,0,0,0,0,0,0,0,0,0,0],"10.1038/ng.449"],[24720702,"Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis.","N Engl J Med",2014,"Kowdley et al.",2,[2,4],[22.75,22.75],22.75,14,12,12,[0,0,0,1,2,3,2,5,0,0,0,1,0,0,0,0],"10.1056/NEJMoa1402355"],[30145927,"Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation.","N Engl J Med",2018,"Obadia et al.",2,[0],[19.85],22.75,23,14,11,[0,0,0,0,0,0,0,0,1,4,5,0,0,2,1,1],"10.1056/NEJMoa1805374"],[31623894,"Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.","Lancet",2019,"CRASH-3 trial collaborators",2,[5,13,0],[8.47,7.75,12.63],22.75,12,12,12,[0,0,0,0,0,0,0,0,0,1,2,1,1,0,4,3],"10.1016/S0140-6736(19)32233-0"],[11742048,"Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both.","N Engl J Med",2001,"Mas et al.",7,[0,5,17],[22.74,16.07,10.83],22.74,15,13,12,[1,3,2,3,0,0,0,1,2,2,0,0,0,1,0,0],"10.1056/NEJMoa011503"],[11852333,"Risk of lymph node metastasis in T1 carcinoma of the colon and rectum.","Dis Colon Rectum",2002,"Nascimbeni et al.",6,[1,4],[20.7,22.74],22.74,14,13,10,[0,1,2,0,5,0,0,1,1,1,0,1,0,0,1,0],"10.1007/s10350-004-6147-7"],[15131563,"Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003.","J Allergy Clin Immunol",2004,"Johansson et al.",7,[12],[18.05],22.74,13,13,10,[2,0,0,4,1,1,1,0,0,2,1,0,1,0,0,0],"10.1016/j.jaci.2003.12.591"],[15710956,"The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial.","Ann Intern Med",2005,"Anthonisen et al.",2,[3],[4.6],22.74,22,15,11,[2,2,3,0,3,0,0,0,2,1,0,1,0,2,0,0],"10.7326/0003-4819-142-4-200502150-00005"],[17548726,"Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study.","Circulation",2007,"Wisløff et al.",2,[0],[18.66],22.74,14,13,11,[3,2,3,1,0,1,0,0,2,0,0,1,0,0,1,0],"10.1161/CIRCULATIONAHA.106.675041"],[18616660,"Preoperative steroid use and risk of postoperative complications in patients with inflammatory bowel disease undergoing abdominal surgery.","Am J Gastroenterol",2008,"Subramanian et al.",0,[4],[22.74],22.74,14,13,10,[2,0,0,1,2,0,2,1,0,1,0,0,0,3,2,0],"10.1111/j.1572-0241.2008.01942.x"],[22082673,"Atrial fibrillation catheter ablation versus surgical ablation treatment (FAST): a 2-center randomized clinical trial.","Circulation",2012,"Boersma et al.",2,[0],[22.74],22.74,24,13,10,[0,2,1,2,0,1,2,1,0,1,0,0,0,6,0,0],"10.1161/CIRCULATIONAHA.111.074047"],[24389304,"Baseline values and changes in liver stiffness measured by transient elastography are associated with severity of fibrosis and outcomes of patients with primary sclerosing cholangitis.","Gastroenterology",2014,"Corpechot et al.",5,[4],[22.74],22.74,13,13,10,[0,0,0,0,1,0,3,0,1,0,0,2,1,3,1,1],"10.1053/j.gastro.2013.12.030"],[25133932,"Perioperative hyperglycemia and risk of adverse events among patients with and without diabetes.","Ann Surg",2015,"Kotagal et al.",5,[7],[12.16],22.74,14,13,11,[0,0,0,0,0,0,1,3,2,3,1,0,0,1,1,2],"10.1097/SLA.0000000000000688"],[26822397,"Gastrectomy plus chemotherapy versus chemotherapy alone for advanced gastric cancer with a single non-curable factor (REGATTA): a phase 3, randomised controlled trial.","Lancet Oncol",2016,"Fujitani et al.",2,[1,4],[22.74,22.74],22.74,14,13,10,[0,0,0,0,0,0,2,1,2,1,0,1,0,3,2,2],"10.1016/S1470-2045(15)00553-7"],[27673306,"Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.","JAMA",2016,"Silverman et 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UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.","Lancet",1996,"",2,[1,4],[22.72,20.63],22.72,14,12,10,[1,1,1,2,0,0,2,2,0,0,1,0,0,1,0,1],""],[10441603,"Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group.","N Engl J Med",1999,"Aupérin et al.",0,[1,3,5],[22.72,20.99,5.92],22.72,18,12,10,[1,0,4,0,0,2,0,0,0,2,2,2,1,0,2,2],"10.1056/NEJM199908123410703"],[11487534,"The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study.","Gastroenterology",2001,"Faubion et al.",5,[4],[22.72],22.72,14,12,10,[3,1,1,0,3,0,2,1,0,0,0,0,1,1,1,0],"10.1053/gast.2001.26279"],[11950911,"Interobserver variability in the diagnosis of ulcerative colitis-associated dysplasia by telepathology.","Mod Pathol",2002,"Odze et al.",7,[4],[22.72],22.72,15,12,11,[1,0,2,2,4,0,1,0,0,1,0,0,1,1,1,0],"10.1038/modpathol.3880534"],[12504397,"Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial.","Lancet",2002,"Hartung et al.",2,[5],[22.72],22.72,13,12,10,[0,1,4,1,0,0,1,1,1,1,1,0,0,2,0,0],"10.1016/S0140-6736(02)12023-X"],[12824459,"The influence of finasteride on the development of prostate cancer.","N Engl J Med",2003,"Thompson et al.",2,[8,9,1],[20.63,20.63,17.66],22.72,14,12,10,[0,2,4,1,1,1,2,0,0,1,0,1,0,1,0,0],"10.1056/NEJMoa030660"],[14684584,"Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis.","Gut",2004,"Mimura et al.",2,[4],[22.72],22.72,15,12,12,[2,1,1,0,1,0,0,1,1,3,0,0,2,3,0,0],"10.1136/gut.53.1.108"],[15197804,"Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, Phase III, double-blind, placebo-controlled trial.","Cancer",2004,"Rosen et al.",2,[1,3,13],[16.26,3.39,11.58],22.72,22,13,10,[4,5,1,3,0,2,1,2,2,0,0,1,0,1,0,0],"10.1002/cncr.20308"],[15657592,"Risk factors of paralysis and functional outcome after recurrent laryngeal nerve monitoring in thyroid surgery.","Surgery",2004,"Dralle et al.",5,[7,3,5],[19.2,6.84,6.84],22.72,14,12,10,[1,0,2,0,1,2,0,2,0,1,0,1,0,1,2,0],"10.1016/j.surg.2004.07.018"],[17512048,"Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data.","Lancet",2007,"Askie et al.",0,[9],[15.97],22.72,13,12,11,[1,2,0,1,0,1,0,0,0,0,1,1,1,3,1,0],"10.1016/S0140-6736(07)60712-0"],[17519278,"Intensive treatment with methotrexate in early rheumatoid arthritis: aiming for remission. Computer Assisted Management in Early Rheumatoid Arthritis (CAMERA, an open-label strategy trial).","Ann Rheum Dis",2007,"Verstappen et al.",2,[11],[22.72],22.72,13,12,10,[2,2,1,1,0,1,2,0,1,0,0,0,0,1,0,1],"10.1136/ard.2007.071092"],[17997389,"Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium--a register-based case-control study.","Am J Obstet Gynecol",2008,"Jacobsen et al.",5,[0,9],[21.24,14.06],22.72,13,12,10,[0,1,1,1,0,1,0,4,0,0,1,1,1,1,0,0],"10.1016/j.ajog.2007.08.041"],[18668682,"Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study.","Inflamm Bowel Dis",2009,"Thia et al.",2,[4],[22.72],22.72,15,13,9,[2,1,0,2,0,0,1,1,0,2,0,0,1,2,2,1],"10.1002/ibd.20608"],[19571282,"Renal and retinal effects of enalapril and losartan in type 1 diabetes.","N Engl J Med",2009,"Mauer et al.",2,[7],[21.83],22.72,19,13,9,[1,2,3,2,0,0,0,1,1,2,2,3,1,0,0,0],"10.1056/NEJMoa0808400"],[20186844,"Clinical course of alcoholic liver cirrhosis: a Danish population-based cohort study.","Hepatology",2010,"Jepsen et al.",5,[4],[22.72],22.72,14,13,9,[0,1,1,1,0,0,0,2,0,2,1,1,1,2,1,0],"10.1002/hep.23500"],[20189239,"Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial.","Lancet",2010,"Ederle et al.",2,[0,5],[22.72,17.16],22.72,22,12,10,[3,1,3,3,0,1,1,0,0,1,0,1,1,0,0,0],"10.1016/S0140-6736(10)60239-5"],[20551454,"Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study.","Gut",2010,"Dent et al.",3,[4],[19.2],22.72,12,12,10,[0,0,0,1,0,0,1,1,1,1,0,2,1,3,1,0],"10.1136/gut.2009.200063"],[20559296,"Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial.","Obesity (Silver Spring)",2011,"Wadden et al.",2,[7],[20.63],22.72,14,12,11,[0,1,1,0,2,1,0,2,1,0,0,2,1,0,0,2],"10.1038/oby.2010.147"],[21376047,"Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C.","Gastroenterology",2011,"Vergniol et al.",5,[4,2],[22.72,10.83],22.72,12,12,10,[0,1,1,0,3,1,1,0,0,0,1,2,0,1,1,0],"10.1053/j.gastro.2011.02.058"],[22453654,"Nurse-led care vs. usual care for patients with atrial fibrillation: results of a randomized trial of integrated chronic care vs. routine clinical care in ambulatory patients with atrial fibrillation.","Eur Heart J",2012,"Hendriks et al.",2,[0],[22.72],22.72,19,12,10,[0,0,1,0,1,3,1,2,0,2,1,1,0,3,0,0],"10.1093/eurheartj/ehs071"],[22504095,"Efficacy of neoadjuvant chemoradiation, followed by liver transplantation, for perihilar cholangiocarcinoma at 12 US centers.","Gastroenterology",2012,"Darwish Murad et al.",5,[1,4],[15.12,22.72],22.72,15,13,9,[0,1,0,1,1,1,1,0,1,1,0,0,1,5,1,0],"10.1053/j.gastro.2012.04.008"],[22910757,"Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis.","JAMA",2012,"Den Ruijter et al.",0,[0],[22.72],22.72,19,14,11,[0,0,1,2,0,2,0,1,2,1,0,0,0,1,1,3],"10.1001/jama.2012.9630"],[23216616,"Cardiovascular events and intensity of treatment in polycythemia vera.","N Engl J Med",2013,"Marchioli et al.",2,[0,10,1],[7.22,18.01,7.47],22.72,13,12,10,[0,0,0,1,1,2,2,1,3,1,0,1,0,0,0,1],"10.1056/NEJMoa1208500"],[23394211,"Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1).","Crit Care",2013,"Kellum et al.",6,[8],[9.77],22.72,15,12,12,[0,0,0,1,1,2,0,1,0,3,2,1,1,1,0,0],"10.1186/cc11454"],[26039526,"Effects of blood pressure-lowering on outcome incidence in hypertension: 5. 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ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group.","Lancet",1995,"",2,[0],[22.52],22.52,20,12,10,[1,2,3,2,2,0,0,1,1,1,0,0,0,1,0,0],""],[10776741,"Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial.","Lancet",2000,"",2,[0,3,11],[20.55,0.0,0.0],22.52,15,14,10,[3,4,3,1,0,0,0,1,0,1,0,0,0,1,0,0],""],[12086759,"Aggressive conventional chemotherapy compared with high-dose chemotherapy with autologous haemopoietic stem-cell transplantation for relapsed chemosensitive Hodgkin's disease: a randomised trial.","Lancet",2002,"Schmitz et al.",2,[1,10],[22.52,22.52],22.52,15,12,10,[2,1,0,3,2,0,0,2,0,1,0,0,0,1,1,2],"10.1016/S0140-6736(02)08938-9"],[15383478,"Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.","Chest",2004,"Geerts et 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A population-based study.","N Engl J Med",1990,"Ekbom et al.",5,[4,1],[22.44,4.04],22.44,12,11,11,[2,0,1,2,2,0,0,1,0,0,2,0,1,1,0,0],"10.1056/NEJM199011013231802"],[3262200,"Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study.","N Engl J Med",1988,"North Italian Endoscopic Club for the St",5,[4],[20.4],22.44,11,11,11,[0,1,1,1,0,0,2,1,0,2,2,0,0,1,0,0],"10.1056/NEJM198810133191505"],[5349366,"Assessment of older people: self-maintaining and instrumental activities of daily living.","Gerontologist",1969,"Lawton et al.",7,[5],[9.3],22.44,11,11,11,[1,4,1,1,0,0,1,0,0,0,1,0,0,1,1,0],""],[8948561,"Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously.","N Engl J Med",1996,"Ely et al.",2,[3],[12.63],22.44,15,11,12,[0,0,2,2,1,1,3,0,0,2,0,1,0,1,0,0],"10.1056/NEJM199612193352502"],[9788453,"Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators.","Lancet",1998,"Hacke et al.",2,[0,5],[22.44,22.44],22.44,13,11,11,[0,1,5,1,1,0,1,1,1,0,0,0,0,0,0,1],"10.1016/s0140-6736(98)08020-9"],[10556226,"Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function.","Circulation",1999,"Kim et al.",7,[0],[22.44],22.44,13,11,12,[2,1,0,1,0,0,2,3,0,1,1,1,0,0,0,0],"10.1161/01.cir.100.19.1992"],[10734022,"Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease.","Gastroenterology",2000,"Dubinsky et al.",3,[4],[17.76],22.44,11,11,11,[1,2,0,1,2,0,2,1,0,0,0,1,0,0,1,0],"10.1016/s0016-5085(00)70140-5"],[10972371,"Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial.","Lancet",2000,"Mease et al.",2,[14,11,13],[20.4,13.81,13.81],22.44,13,11,11,[1,3,1,0,1,0,1,1,3,0,1,0,0,0,0,0],"10.1016/S0140-6736(00)02530-7"],[11690728,"Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale.","Pain",2001,"Farrar et al.",3,[5,11,13],[4.04,1.0,4.65],22.44,12,11,11,[3,0,0,2,0,0,0,0,1,1,1,1,0,1,0,1],"10.1016/S0304-3959(01)00349-9"],[14736927,"Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer.","N Engl J Med",2004,"Arriagada et al.",2,[1,3],[22.44,22.44],22.44,11,11,11,[0,1,2,2,2,1,0,0,0,0,0,1,1,0,1,0],"10.1056/NEJMoa031644"],[15016487,"Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.","Lancet",2004,"Hacke et al.",7,[0,5],[22.44,22.44],22.44,15,11,11,[1,3,5,1,1,0,1,1,0,0,0,0,0,0,0,1],"10.1016/S0140-6736(04)15692-4"],[15590950,"Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction.","N Engl J Med",2004,"Hohnloser et al.",2,[0],[22.44],22.44,34,17,8,[0,1,5,1,1,2,2,1,1,1,0,0,0,1,2,0],"10.1056/NEJMoa041489"],[16306519,"Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis.","N Engl J Med",2005,"Ginzler et al.",2,[11,8],[22.44,15.17],22.44,13,11,12,[0,3,2,0,1,0,0,1,1,0,1,0,0,2,0,1],"10.1056/NEJMoa043731"],[16848804,"The risk of retention of the capsule endoscope in patients with known or suspected Crohn's disease.","Am J Gastroenterol",2006,"Cheifetz et al.",5,[4],[22.44],22.44,11,11,11,[1,0,1,2,3,0,1,0,1,0,0,0,0,0,1,1],"10.1111/j.1572-0241.2006.00761.x"],[17980284,"Stenting of the venous outflow in chronic venous disease: long-term stent-related outcome, clinical, and hemodynamic result.","J Vasc Surg",2007,"Neglén et al.",7,[0],[22.44],22.44,12,11,11,[0,0,1,3,1,1,0,0,0,2,0,1,1,2,0,0],"10.1016/j.jvs.2007.06.046"],[18602922,"The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations.","Gastroenterology",2008,"Senter et al.",7,[1,4,7],[22.44,18.36,13.81],22.44,15,11,14,[0,1,2,1,4,1,0,0,0,0,0,0,0,1,1,1],"10.1053/j.gastro.2008.04.026"],[19160234,"Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery.","Cochrane Database Syst Rev",2009,"Rasmussen et al.",0,[0,3],[13.27,1.0],22.44,20,13,10,[0,3,3,2,0,0,2,1,1,0,1,1,0,0,0,0],"10.1002/14651858.CD004318.pub2"],[19561486,"Timing of antimicrobial prophylaxis and the risk of surgical site infections: results from the Trial to Reduce Antimicrobial Prophylaxis Errors.","Ann Surg",2009,"Steinberg et al.",5,[2],[10.83],22.44,15,11,12,[1,1,2,1,1,0,4,1,0,0,0,0,0,1,0,0],"10.1097/SLA.0b013e3181ad5fca"],[19679613,"Hormonal contraception and risk of venous thromboembolism: national follow-up study.","BMJ",2009,"Lidegaard et al.",7,[0],[15.78],22.44,17,11,12,[0,2,4,1,0,0,2,0,1,0,0,1,0,1,0,1],"10.1136/bmj.b2890"],[19933596,"Influence of race/ethnicity on response to lupus nephritis treatment: the ALMS study.","Rheumatology (Oxford)",2010,"Isenberg et al.",2,[11,8],[19.73,17.76],22.44,14,11,12,[0,3,1,0,1,0,0,2,1,0,1,0,1,3,0,0],"10.1093/rheumatology/kep346"],[20039413,"Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial.","Arthritis Rheum",2010,"Merrill et al.",2,[11],[20.4],22.44,12,11,12,[1,2,1,0,0,2,0,1,1,0,1,0,0,0,2,0],"10.1002/art.27233"],[22033451,"Hepatitis B virus (HBV) reactivation in patients receiving tumor necrosis factor (TNF)-targeted therapy: analysis of 257 cases.","Medicine (Baltimore)",2011,"Pérez-Alvarez et al.",0,[4,2],[13.81,11.84],22.44,14,11,11,[0,1,0,2,1,3,0,0,3,0,1,1,0,0,1,0],"10.1097/MD.0b013e3182380a76"],[22612596,"Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy.","N Engl J Med",2012,"Schoen et al.",2,[1,4],[19.73,20.4],22.44,14,11,12,[0,0,2,0,1,2,1,3,0,1,1,0,0,1,0,0],"10.1056/NEJMoa1114635"],[22742517,"The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology.","Arch Pathol Lab Med",2012,"Darragh et al.",4,[1,9,2],[17.06,15.78,11.38],22.44,12,11,11,[0,0,1,0,1,2,0,3,0,1,1,0,2,0,1,0],"10.5858/arpa.LGT200570"],[22892336,"Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy: a meta-analysis.","Gastroenterology",2012,"Bacq et al.",0,[4,9],[17.76,12.63],22.44,11,11,11,[0,0,0,0,0,2,1,1,0,1,2,0,2,0,1,1],"10.1053/j.gastro.2012.08.004"],[25082583,"Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials.","J Am Coll Cardiol",2014,"Boekholdt et al.",0,[0],[14.66],22.44,18,13,12,[0,0,0,0,1,3,1,4,2,0,1,0,0,0,1,1],"10.1016/j.jacc.2014.02.615"],[27217453,"No Evidence for the Benefit of Gonadotropin-Releasing Hormone Agonist in Preserving Ovarian Function and Fertility in Lymphoma Survivors Treated With Chemotherapy: Final Long-Term Report of a Prospective Randomized Trial.","J Clin Oncol",2016,"Demeestere et al.",2,[1,9,7],[17.76,10.16,6.2],22.44,12,11,11,[0,0,0,0,0,0,1,4,2,1,0,1,0,1,1,1],"10.1200/JCO.2015.65.8864"],[28240969,"Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study.","J Clin Oncol",2017,"Rosenthal et al.",5,[1,9,7],[22.44,15.78,15.78],22.44,11,11,11,[0,0,0,0,0,0,1,2,1,0,1,1,1,2,2,0],"10.1200/JCO.2016.69.9330"],[28402085,"Decision aids for people facing health treatment or screening decisions.","Cochrane Database Syst Rev",2017,"Stacey et al.",1,[0],[12.24],22.44,24,13,11,[0,0,0,0,0,0,0,2,2,2,3,2,3,1,0,1],"10.1002/14651858.CD001431.pub5"],[2668130,"Development and validation of an endoscopic index of the severity for Crohn's disease: a prospective multicentre study. Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du Tube Digestif (GETAID).","Gut",1989,"Mary et al.",3,[4],[22.43],22.43,14,13,11,[0,0,2,0,0,0,1,3,1,0,0,0,0,2,5,0],"10.1136/gut.30.7.983"],[18977996,"Prevention of rickets and vitamin D deficiency in infants, children, and adolescents.","Pediatrics",2008,"Wagner et al.",7,[7,13],[10.83,6.2],22.43,13,13,11,[3,3,2,0,0,0,1,3,0,0,0,1,0,0,0,0],"10.1542/peds.2008-1862"],[20921465,"Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study.","J Clin Oncol",2010,"Douillard et al.",2,[1,4],[22.43,22.43],22.43,21,13,8,[1,2,1,2,1,0,2,2,1,1,2,0,2,2,1,0],"10.1200/JCO.2009.27.4860"],[23168366,"Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial.","Lancet Oncol",2013,"Bennouna et al.",2,[1,4],[22.43,22.43],22.43,19,11,9,[0,0,1,3,1,1,2,1,1,1,2,0,2,1,1,1],"10.1016/S1470-2045(12)70477-1"],[28835439,"Management of rivaroxaban- or apixaban-associated major bleeding with prothrombin complex concentrates: a cohort study.","Blood",2017,"Majeed et al.",5,[0],[17.85],22.43,15,13,11,[0,0,0,0,0,0,0,3,0,1,2,0,2,3,2,0],"10.1182/blood-2017-05-782060"],[28885881,"Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer.","N Engl J Med",2017,"Antonia et al.",2,[1,3],[22.43,20.53],22.43,15,13,12,[0,0,0,0,0,0,0,0,0,1,2,2,2,2,5,0],"10.1056/NEJMoa1709937"],[2032882,"Tolerance of normal tissue to therapeutic irradiation.","Int J Radiat Oncol Biol Phys",1991,"Emami et al.",6,[1],[18.99],22.4,17,13,9,[1,1,1,0,0,4,1,0,0,0,1,4,0,1,2,1],"10.1016/0360-3016(91)90171-y"],[11834007,"Yearly rupture or dissection rates for thoracic aortic aneurysms: simple prediction based on size.","Ann Thorac Surg",2002,"Davies et al.",7,[0],[22.4],22.4,22,11,10,[0,0,0,2,1,1,0,1,1,0,2,1,2,1,0,1],"10.1016/s0003-4975(01)03236-2"],[11984739,"Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers.","Gastric Cancer",2000,"Gotoda et al.",7,[1,4],[22.4,22.4],22.4,13,11,10,[2,0,0,0,1,1,1,0,1,2,1,1,0,0,1,2],"10.1007/pl00011720"],[15685546,"Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.","Gastroenterology",2005,"Castéra et al.",7,[4,2],[20.25,9.93],22.4,18,13,9,[2,0,2,3,2,1,1,1,0,1,1,0,0,3,0,0],"10.1053/j.gastro.2004.11.018"],[17119114,"Late cardiotoxicity after treatment for Hodgkin lymphoma.","Blood",2007,"Aleman et al.",5,[1,0,10],[22.4,9.48,3.1],22.4,14,11,12,[1,2,1,0,1,1,2,0,0,1,1,1,2,0,0,0],"10.1182/blood-2006-07-034405"],[17193820,"Gastrointestinal stromal tumors: pathology and prognosis at different sites.","Semin Diagn Pathol",2006,"Miettinen et al.",6,[1,4,5],[22.4,22.4,0.0],22.4,14,11,10,[0,2,1,1,0,0,2,1,1,0,0,2,2,1,1,0],"10.1053/j.semdp.2006.09.001"],[18669577,"Needle track seeding following biopsy of liver lesions in the diagnosis of hepatocellular cancer: a systematic review and meta-analysis.","Gut",2008,"Silva et al.",0,[1,4],[22.4,22.4],22.4,17,11,12,[0,2,1,0,1,0,0,1,1,2,0,2,1,2,0,1],"10.1136/gut.2008.149062"],[19657122,"A randomized trial of vertebroplasty for osteoporotic spinal fractures.","N Engl J Med",2009,"Kallmes et al.",2,[13,7],[22.4,7.89],22.4,14,11,10,[2,0,1,3,0,1,1,2,0,1,0,0,1,0,1,1],"10.1056/NEJMoa0900563"],[20197533,"Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis.","JAMA",2010,"Briel et al.",0,[3],[17.16],22.4,16,11,9,[1,0,1,0,1,0,2,1,2,2,0,0,0,2,1,1],"10.1001/jama.2010.218"],[20382983,"Endovascular versus open repair of abdominal aortic aneurysm.","N Engl J Med",2010,"Greenhalgh et al.",2,[0],[22.4],22.4,18,11,10,[3,1,1,2,0,1,0,2,0,1,0,1,1,0,0,1],"10.1056/NEJMoa0909305"],[22289873,"Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies.","Clin Gastroenterol Hepatol",2012,"Jess et al.",0,[4,1],[20.25,8.47],22.4,12,11,11,[0,0,1,1,1,0,0,2,1,1,2,0,1,1,1,0],"10.1016/j.cgh.2012.01.010"],[23306100,"Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial.","Lancet Oncol",2013,"Gravis et al.",2,[1,8,9],[22.4,22.4,22.4],22.4,15,11,10,[0,0,0,0,2,1,1,2,1,1,2,0,2,1,1,0],"10.1016/S1470-2045(12)70560-0"],[26240224,"Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group.","J Clin Oncol",2015,"Palumbo et al.",7,[0,1,10],[22.4,22.4,22.4],22.4,14,11,10,[0,0,0,0,0,3,2,1,1,1,1,0,1,2,1,1],"10.1200/JCO.2015.61.2267"],[29485925,"Balanced Crystalloids versus Saline in Critically Ill Adults.","N Engl J Med",2018,"Semler et al.",2,[8],[2.69],22.4,14,13,13,[0,0,0,0,0,0,0,0,1,4,0,2,3,3,0,0],"10.1056/NEJMoa1711584"],[33667417,"Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial.","Lancet",2021,"Davies et al.",2,[7],[18.05],22.4,14,13,12,[0,0,0,0,0,0,0,0,0,0,0,2,1,3,2,5],"10.1016/S0140-6736(21)00213-0"],[17762336,"The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours.","J Thorac Oncol",2007,"Goldstraw et al.",7,[1,3],[22.39,22.39],22.39,16,14,9,[2,2,4,1,3,2,0,1,1,0,0,0,0,0,0,0],"10.1097/JTO.0b013e31812f3c1a"],[26115797,"Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial.","Lancet Oncol",2015,"Oza et al.",2,[1,7,9],[22.39,22.39,22.39],22.39,15,14,9,[0,0,0,0,0,1,0,0,4,0,3,1,1,3,1,1],"10.1016/S1470-2045(15)00086-8"],[11926784,"Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials.","Ann Intern Med",2002,"Whelton et al.",0,[0,7],[17.13,6.77],22.35,29,17,8,[3,2,2,1,1,0,0,3,4,0,0,1,1,0,1,1],"10.7326/0003-4819-136-7-200204020-00006"],[16534009,"The Seattle Heart Failure Model: prediction of survival in heart failure.","Circulation",2006,"Levy et al.",5,[0],[22.35],22.35,21,16,8,[0,3,3,0,1,1,1,0,2,3,1,0,0,1,0,0],"10.1161/CIRCULATIONAHA.105.584102"],[20837828,"Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation.","Arch Intern Med",2010,"Hansen et al.",5,[0,5],[19.68,1.0],22.35,26,16,8,[1,3,0,3,1,4,1,4,0,0,1,0,0,1,0,0],"10.1001/archinternmed.2010.271"],[18565860,"Increased mortality after dronedarone therapy for severe heart failure.","N Engl J Med",2008,"Køber et 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The National Polyp Study Workgroup.","N Engl J Med",1993,"Winawer et al.",2,[1,4],[22.18,22.18],22.18,13,13,10,[0,5,1,0,2,0,0,0,1,2,0,1,0,1,0,0],"10.1056/NEJM199304013281301"],[14534891,"Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial.","Cancer",2003,"Rosen et al.",2,[1,13,0],[19.42,7.47,5.29],22.18,14,13,10,[4,1,2,3,1,0,0,1,0,2,0,0,0,0,0,0],"10.1002/cncr.11701"],[17306354,"Further fatalities caused by anaphylactic reactions to food, 2001-2006.","J Allergy Clin Immunol",2007,"Bock et al.",5,[12],[21.36],22.18,15,13,10,[2,0,0,4,1,0,2,0,0,1,0,1,0,2,0,0],"10.1016/j.jaci.2006.12.622"],[16732012,"Prevalence of diabetes complications in adolescents with type 2 compared with type 1 diabetes.","Diabetes Care",2006,"Eppens et al.",7,[7],[18.66],22.16,19,15,8,[2,2,3,4,1,0,2,2,0,2,1,0,0,0,0,0],"10.2337/dc05-2470"],[18799552,"Effectiveness of maternal influenza immunization in mothers and infants.","N Engl J Med",2008,"Zaman et al.",2,[2,3],[18.53,18.53],22.16,16,13,9,[0,0,2,2,0,4,1,1,0,0,0,1,1,2,2,0],"10.1056/NEJMoa0708630"],[20362695,"Complication rate of percutaneous liver biopsies among persons with advanced chronic liver disease in the HALT-C trial.","Clin Gastroenterol Hepatol",2010,"Seeff et al.",3,[4,2],[16.89,1.9],22.16,14,13,9,[0,0,1,0,2,0,1,1,1,1,2,0,0,3,0,1],"10.1016/j.cgh.2010.03.025"],[21945953,"Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped.","Gastroenterology",2012,"Louis et al.",5,[4],[22.16],22.16,13,13,9,[0,0,2,2,0,0,1,2,1,0,1,0,1,2,1,0],"10.1053/j.gastro.2011.09.034"],[24148622,"A MELD-based model to determine risk of mortality among patients with acute variceal bleeding.","Gastroenterology",2014,"Reverter et al.",3,[4],[22.16],22.16,13,13,9,[0,0,0,0,0,2,1,1,0,2,2,1,1,0,2,1],"10.1053/j.gastro.2013.10.018"],[27043165,"Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.","N Engl J Med",2016,"Kudenchuk et al.",2,[0],[22.16],22.16,17,15,8,[0,0,0,0,0,0,1,3,1,1,2,2,0,2,3,1],"10.1056/NEJMoa1514204"],[10601507,"A randomized study of the prevention of sudden death in patients with coronary artery disease. 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Bowel Dis",2001,"Shen et al.",2,[4],[21.86],21.86,13,11,11,[2,0,1,1,1,0,0,1,0,1,0,0,2,2,2,0],"10.1097/00054725-200111000-00004"],[11991871,"Epidemiology of obstructive sleep apnea: a population health perspective.","Am J Respir Crit Care Med",2002,"Young et al.",6,[5,3],[16.6,11.38],21.86,11,11,10,[1,1,1,2,2,1,1,0,1,0,0,0,1,0,0,0],"10.1164/rccm.2109080"],[14681504,"The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia.","N Engl J Med",2003,"McConnell et al.",2,[8,9],[21.86,21.86],21.86,11,11,10,[1,1,1,0,0,1,2,0,0,1,0,0,1,2,1,0],"10.1056/NEJMoa030656"],[15726658,"Pantoprazole reduces the size of postbanding ulcers after variceal band ligation: a randomized, controlled trial.","Hepatology",2005,"Shaheen et al.",2,[4],[19.76],21.86,13,11,10,[0,3,1,1,0,0,1,2,0,1,1,1,0,0,1,0],"10.1002/hep.20593"],[15758012,"Anemia of chronic disease.","N Engl J Med",2005,"Weiss et 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ACE-Inhibitor Myocardial Infarction Collaborative Group.","Lancet",2000,"Flather et al.",0,[0],[21.82],21.82,18,13,8,[1,1,1,0,2,1,1,1,0,1,0,0,1,2,1,1],"10.1016/s0140-6736(00)02212-1"],[25791214,"Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial.","Lancet",2015,"Valgimigli et al.",2,[0],[21.78],21.78,24,16,8,[0,0,0,0,2,2,2,7,1,1,0,2,1,0,1,0],"10.1016/S0140-6736(15)60292-6"],[33190147,"Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk: The STRENGTH Randomized Clinical Trial.","JAMA",2020,"Nicholls et al.",2,[0],[13.82],21.78,18,15,12,[0,0,0,0,0,0,0,0,0,0,2,2,0,3,3,5],"10.1001/jama.2020.22258"],[22512481,"Radiotherapy with or without chemotherapy in muscle-invasive bladder cancer.","N Engl J Med",2012,"James et al.",2,[1,8],[21.77,21.77],21.77,21,15,8,[0,0,2,1,0,1,2,3,1,2,0,4,0,2,3,0],"10.1056/NEJMoa1106106"],[24915261,"Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications.","JAMA",2014,"Sjöström et al.",5,[7],[19.84],21.73,17,14,13,[0,0,0,0,1,2,1,0,3,4,0,4,0,0,0,0],"10.1001/jama.2014.5988"],[15470212,"Protected carotid-artery stenting versus endarterectomy in high-risk patients.","N Engl J Med",2004,"Yadav et al.",2,[0,5],[21.72,17.1],21.72,24,13,8,[4,1,2,2,0,1,1,1,0,1,0,1,1,2,0,0],"10.1056/NEJMoa040127"],[16530578,"Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.","Lancet",2006,"Meggitt et al.",2,[14,12,17],[13.57,10.15,10.15],21.72,14,13,8,[2,0,0,1,1,2,1,0,1,0,1,1,0,1,1,2],"10.1016/S0140-6736(06)68340-2"],[23728631,"Physician advice for smoking cessation.","Cochrane Database Syst Rev",2013,"Stead et al.",0,[0],[9.93],21.72,26,14,9,[0,0,0,0,4,0,3,1,0,0,1,0,2,3,1,2],"10.1002/14651858.CD000165.pub4"],[10109801,"EuroQol--a new facility for the measurement of health-related quality of life.","Health Policy",1990,"EuroQol Group",7,[0],[4.65],21.7,11,11,11,[0,0,1,0,1,0,0,1,2,0,0,0,3,1,0,2],"10.1016/0168-8510(90)90421-9"],[10484010,"Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions.","Am J Gastroenterol",1999,"Brunt et al.",5,[4],[21.7],21.7,13,11,13,[0,1,0,1,3,0,0,0,0,0,1,3,0,0,1,1],"10.1111/j.1572-0241.1999.01377.x"],[11172189,"Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure.","N Engl J Med",2001,"Hilbert et al.",2,[3],[13.27],21.7,11,11,11,[2,0,0,0,1,1,1,3,0,0,0,2,0,1,0,0],"10.1056/NEJM200102153440703"],[11495620,"Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial.","JAMA",2001,"Merrer et al.",2,[2,0],[16.24,5.08],21.7,13,11,12,[1,3,0,4,0,0,1,0,0,0,0,0,1,0,1,1],"10.1001/jama.286.6.700"],[14662233,"Acyclovir prophylaxis to prevent herpes simplex virus recurrence at delivery: a systematic review.","Obstet Gynecol",2003,"Sheffield et al.",0,[2,9,14],[21.7,21.7,4.65],21.7,11,11,11,[1,0,0,0,2,2,2,0,0,0,0,0,0,1,2,1],"10.1016/j.obstetgynecol.2003.08.015"],[14747370,"The classification of glomerulonephritis in systemic lupus erythematosus revisited.","J Am Soc Nephrol",2004,"Weening et al.",7,[8,11],[18.96,15.17],21.7,14,11,13,[0,4,0,0,1,1,0,1,1,0,2,0,0,2,0,0],"10.1097/01.asn.0000108969.21691.5d"],[16549834,"Incidence, risk factors, and outcomes of catheter-related thrombosis in adult patients with cancer.","J Clin Oncol",2006,"Lee et al.",5,[0,1],[21.7,15.17],21.7,12,11,11,[1,2,2,0,2,0,0,0,0,2,1,0,0,2,0,0],"10.1200/JCO.2005.03.5600"],[17258667,"Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study.","Lancet",2007,"Wahlgren et al.",3,[0,5],[21.7,21.7],21.7,13,11,11,[1,2,5,1,0,0,1,1,1,0,0,0,0,0,0,0],"10.1016/S0140-6736(07)60149-4"],[17582071,"The HBV drug entecavir - 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The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial.","JAMA",2003,"Pepine et al.",2,[0],[21.61],21.61,17,11,9,[1,1,3,1,2,1,0,1,1,1,0,0,1,1,0,0],"10.1001/jama.290.21.2805"],[14657227,"FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study.","J Clin Oncol",2004,"Tournigand et al.",2,[1,4],[21.61,21.61],21.61,17,11,9,[2,2,2,3,1,1,1,1,0,2,1,0,0,0,1,0],"10.1200/JCO.2004.05.113"],[17098085,"Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study.","Lancet",2006,"Lindström et al.",2,[7],[19.41],21.61,16,11,11,[1,1,2,1,2,1,0,0,2,1,0,1,0,1,0,1],"10.1016/S0140-6736(06)69701-8"],[18549877,"Neither multiple tumors nor portal hypertension are surgical contraindications for hepatocellular carcinoma.","Gastroenterology",2008,"Ishizawa et 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Cancer",2014,"Golfieri et al.",2,[1,4],[21.51,21.51],21.51,16,10,11,[0,0,0,0,0,1,2,1,1,1,1,1,2,2,2,0],"10.1038/bjc.2014.199"],[12716665,"Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials.","Am J Clin Nutr",2003,"Mensink et al.",0,[0],[11.05],21.5,19,12,11,[2,1,1,2,1,2,0,0,2,0,1,0,0,0,0,1],"10.1093/ajcn/77.5.1146"],[14762784,"Improved clinical outcome using polytetrafluoroethylene-coated stents for TIPS: results of a randomized study.","Gastroenterology",2004,"Bureau et al.",2,[4,0],[21.5,0.0],21.5,12,12,9,[0,2,1,0,0,1,0,1,1,0,2,0,0,2,1,1],"10.1053/j.gastro.2003.11.016"],[15001324,"Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial.","Lancet",2004,"Klareskog et 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older adults: the cardiovascular health study.","Circulation",2008,"Mozaffarian et al.",5,[0],[21.5],21.5,18,12,9,[0,1,1,0,0,1,2,1,0,1,1,1,0,4,0,0],"10.1161/CIRCULATIONAHA.108.785626"],[19558997,"Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis.","Clin Gastroenterol Hepatol",2009,"Siegel et al.",0,[4,1,10],[21.5,1.0,0.0],21.5,13,12,9,[3,2,1,0,0,0,1,1,1,1,0,0,0,2,1,0],"10.1016/j.cgh.2009.01.004"],[19273724,"Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest.","Circulation",2009,"Atkins et al.",5,[0],[16.8],21.48,19,13,9,[0,0,1,3,4,2,1,1,1,0,0,1,0,0,2,0],"10.1161/CIRCULATIONAHA.108.802678"],[24486266,"Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: the NXT trial (Analysis of Coronary Blood Flow 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activity of etoricoxib, a selective cox-2 inhibitor in inflammatory bowel diseases.","Am J Gastroenterol",2006,"El Miedany et al.",2,[4],[13.28],21.4,15,11,11,[1,1,1,3,1,0,1,2,1,1,0,0,0,1,1,0],"10.1111/j.1572-0241.2006.00384.x"],[18056526,"Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial.","Circulation",2007,"Wiviott et al.",2,[0],[21.36],21.36,18,12,10,[3,2,3,3,1,1,0,2,0,0,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.107.740324"],[19656558,"Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia after 36 weeks' gestation (HYPITAT): a multicentre, open-label randomised controlled trial.","Lancet",2009,"Koopmans et al.",2,[9,0],[21.36,11.58],21.36,14,12,10,[0,0,0,0,0,3,2,0,2,2,0,2,0,1,0,1],"10.1016/S0140-6736(09)60736-4"],[21492336,"Trans-peritoneal fine needle aspiration biopsy of hilar cholangiocarcinoma is associated with disease dissemination.","HPB (Oxford)",2011,"Heimbach et al.",5,[1,4],[18.57,21.36],21.36,14,12,10,[0,0,1,0,1,0,0,0,0,1,1,0,3,3,3,0],"10.1111/j.1477-2574.2011.00298.x"],[21532466,"Comparison between endoscopic and surgical resection of mucosal esophageal adenocarcinoma in Barrett's esophagus at two high-volume centers.","Ann Surg",2011,"Pech et al.",5,[1,4],[19.39,21.36],21.36,12,12,10,[0,0,1,2,2,1,0,0,0,0,0,1,0,4,1,0],"10.1097/SLA.0b013e31821d4bf6"],[22031728,"Screening by chest radiograph and lung cancer mortality: the Prostate, Lung, Colorectal, and Ovarian (PLCO) randomized trial.","JAMA",2011,"Oken et al.",2,[1,3],[21.36,21.36],21.36,13,12,11,[0,0,3,2,1,1,1,2,0,0,2,0,0,0,0,0],"10.1001/jama.2011.1591"],[22100906,"Gemcitabine versus gemcitabine plus dalteparin 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al.",2,[14,11,13],[21.36,14.63,14.63],21.36,14,12,10,[0,0,0,1,1,2,0,2,3,2,2,0,0,0,0,0],"10.1016/S0140-6736(13)60594-2"],[26519602,"Management of the critically ill patient with cirrhosis: A multidisciplinary perspective.","J Hepatol",2016,"Nadim et al.",6,[4],[18.63],21.36,12,12,10,[0,0,0,0,0,0,0,2,1,1,1,0,2,3,2,0],"10.1016/j.jhep.2015.10.019"],[27124745,"Coagulation parameters and major bleeding in critically ill patients with cirrhosis.","Hepatology",2016,"Drolz et al.",5,[4],[18.63],21.36,12,12,10,[0,0,0,0,0,0,0,1,2,1,1,0,0,5,1,1],"10.1002/hep.28628"],[28828487,"Continuous Glucose Monitoring Versus Usual Care in Patients With Type 2 Diabetes Receiving Multiple Daily Insulin Injections: A Randomized Trial.","Ann Intern Med",2017,"Beck et al.",2,[7],[21.36],21.36,16,12,10,[0,0,0,0,0,0,0,0,1,2,3,1,2,1,0,4],"10.7326/M16-2855"],[29726345,"Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and 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cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.","Lancet",2011,"Davies et al.",0,[1],[21.24],21.24,14,11,10,[0,0,0,1,1,4,1,1,0,1,0,0,0,3,0,1],"10.1016/S0140-6736(11)60993-8"],[21852264,"Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian Randomized Controlled Trial--SCORE.","J Natl Cancer Inst",2011,"Segnan et al.",2,[1,4],[21.24,21.24],21.24,15,11,12,[0,0,3,1,2,2,1,2,0,0,1,0,1,0,0,0],"10.1093/jnci/djr284"],[22335737,"Semuloparin for thromboprophylaxis in patients receiving chemotherapy for cancer.","N Engl J Med",2012,"Agnelli et al.",2,[1,0],[18.57,15.95],21.24,12,11,10,[0,0,3,2,1,0,1,0,1,1,1,0,0,2,0,0],"10.1056/NEJMoa1108898"],[23583249,"Left atrial appendage closure with the Watchman device in patients with a contraindication for oral anticoagulation: the ASAP study (ASA Plavix Feasibility Study With Watchman Left Atrial Appendage Closure Technology).","J Am 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bleeding gastric varices in people with portal hypertension.","Cochrane Database Syst Rev",2015,"Ríos Castellanos et al.",0,[4],[21.24],21.24,11,11,10,[0,0,0,0,0,0,1,1,1,1,2,2,0,1,2,0],"10.1002/14651858.CD010180.pub2"],[26308684,"Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension.","N Engl J Med",2015,"Galiè et al.",2,[3,0],[17.16,14.63],21.24,15,11,10,[0,0,0,0,1,1,0,3,1,1,0,0,2,0,1,3],"10.1056/NEJMoa1413687"],[26896734,"Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients With Cirrhosis and Hepatorenal Syndrome Type 1.","Gastroenterology",2016,"Boyer et al.",2,[4,8],[19.73,8.18],21.24,14,13,9,[0,0,0,0,0,0,1,1,2,0,2,1,1,4,2,0],"10.1053/j.gastro.2016.02.026"],[27026510,"Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease in a non-cardiac surgery setting: systematic review and meta-analysis.","BMJ",2016,"Docherty et 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The Diabetes Control and Complications Trial Research Group.","Diabetes Care",2000,"Diabetes Control and Complications Trial",2,[7,0,9],[20.32,12.23,2.69],21.23,18,12,8,[2,3,2,1,1,1,1,0,0,2,2,1,0,1,0,0],"10.2337/diacare.23.8.1084"],[24963566,"Atrial fibrillation in patients with cryptogenic stroke.","N Engl J Med",2014,"Gladstone et al.",2,[0,5],[21.19,12.13],21.19,21,14,9,[0,0,0,0,1,2,2,2,0,3,0,1,0,4,1,0],"10.1056/NEJMoa1311376"],[19160175,"Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease.","Cochrane Database Syst Rev",2009,"Prefontaine et al.",0,[4],[21.17],21.17,12,12,10,[2,1,0,3,0,1,1,2,0,0,0,0,0,2,0,0],"10.1002/14651858.CD000067.pub2"],[19190314,"Estimated radiation dose associated with cardiac CT angiography.","JAMA",2009,"Hausleiter et al.",5,[0],[21.17],21.17,12,12,10,[3,1,4,1,1,1,1,0,0,0,0,0,0,0,0,0],"10.1001/jama.2009.54"],[19520336,"Diagnostic and prognostic value of absence of coronary artery calcification.","JACC Cardiovasc 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The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.","Lancet",1993,"",2,[0],[21.1],21.1,23,15,7,[0,2,0,0,1,1,2,2,1,1,1,2,1,1,2,1],""],[23075175,"Peripheral-blood stem cells versus bone marrow from unrelated donors.","N Engl J Med",2012,"Anasetti et al.",2,[10,1],[19.99,15.66],21.02,14,14,7,[0,0,1,0,0,0,1,1,2,1,2,1,1,1,1,2],"10.1056/NEJMoa1203517"],[26264829,"Surgical approach to hysterectomy for benign gynaecological disease.","Cochrane Database Syst Rev",2015,"Aarts et al.",0,[9],[21.02],21.02,16,12,8,[0,0,0,0,1,1,1,1,2,2,3,1,1,1,1,0],"10.1002/14651858.CD003677.pub5"],[8026269,"Colonoscopy of acute colitis. 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The National Cancer Institute of Canada Clinical Trials Group.","J Clin Oncol",1996,"Coppin et al.",2,[1,8],[20.93,20.93],20.93,15,13,8,[2,1,2,1,0,0,2,1,0,1,0,3,0,0,2,0],"10.1200/JCO.1996.14.11.2901"],[17093942,"High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study.","Diabetologia",2007,"Prompers et al.",5,[0,14,7],[17.07,17.07,15.61],20.92,15,14,8,[0,1,0,1,0,5,0,0,1,1,0,1,1,2,0,1],"10.1007/s00125-006-0491-1"],[12163425,"Prediction of long-term prognosis in 12 169 men referred for cardiac rehabilitation.","Circulation",2002,"Kavanagh et al.",5,[0],[20.89],20.89,18,12,11,[2,2,2,2,0,0,0,1,1,0,0,1,0,2,0,0],"10.1161/01.cir.0000024413.15949.ed"],[17444589,"Response to pneumococcal vaccine in patients with early rheumatoid arthritis receiving infliximab plus methotrexate or methotrexate alone.","J Rheumatol",2007,"Visvanathan et al.",2,[11,2],[20.89,7.47],20.89,14,12,9,[3,1,0,1,1,2,1,0,2,0,0,0,1,0,0,0],""],[20047898,"Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of 'bridging' antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel.","Br J Anaesth",2010,"Savonitto et 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A harmonised meta-analysis of data from more than 1 million men and women.","Lancet",2016,"Ekelund et al.",5,[0],[13.27],20.85,12,11,11,[0,0,0,0,0,0,0,0,2,3,2,2,0,0,2,1],"10.1016/S0140-6736(16)30370-1"],[27989373,"Bleeding after invasive procedures is rare and unpredicted by platelet counts in cirrhotic patients with thrombocytopenia.","Eur J Intern Med",2017,"Napolitano et al.",5,[4,10],[18.05,7.75],20.85,13,11,11,[0,0,0,0,0,0,0,0,1,2,2,0,0,3,2,1],"10.1016/j.ejim.2016.11.007"],[29562147,"Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer.","N Engl J Med",2018,"Choi et al.",2,[1,4,2],[14.44,20.85,4.65],20.85,12,11,12,[0,0,0,0,0,0,0,0,1,1,2,0,0,1,4,2],"10.1056/NEJMoa1708423"],[31790344,"Pembrolizumab As Second-Line Therapy in Patients With Advanced Hepatocellular Carcinoma in KEYNOTE-240: A Randomized, Double-Blind, Phase III Trial.","J Clin Oncol",2020,"Finn et al.",2,[1,4],[20.85,20.85],20.85,14,11,11,[0,0,0,0,0,0,0,0,0,1,3,2,1,5,1,0],"10.1200/JCO.19.01307"],[8298418,"Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration.","BMJ",1994,"",0,[0,5],[18.69,4.23],20.84,32,16,9,[4,2,6,4,1,1,1,0,1,0,0,1,1,0,0,0],""],[16243088,"Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trial.","Lancet",2005,"Kullberg et al.",2,[2],[20.84],20.84,14,13,9,[4,3,1,1,1,1,2,0,0,0,0,0,0,0,0,0],"10.1016/S0140-6736(05)67490-9"],[20181971,"Timing of initiation of antiretroviral drugs during tuberculosis therapy.","N Engl J Med",2010,"Abdool Karim et al.",2,[2,12],[20.84,14.7],20.84,14,13,9,[2,3,4,0,1,1,0,0,2,1,0,0,0,0,0,0],"10.1056/NEJMoa0905848"],[30738780,"Addition of radium-223 to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases (ERA 223): a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet Oncol",2019,"Smith et al.",2,[1,8,9],[20.84,18.24,18.24],20.84,17,13,9,[0,0,0,0,0,0,0,0,0,4,1,2,2,3,2,3],"10.1016/S1470-2045(18)30860-X"],[32580883,"Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial.","Lancet",2020,"Murray Brunt et al.",2,[1],[20.84],20.84,14,13,10,[0,0,0,0,0,0,0,0,0,1,2,2,2,3,1,2],"10.1016/S0140-6736(20)30932-6"],[17105759,"Coronary intervention for persistent occlusion after myocardial infarction.","N Engl J Med",2006,"Hochman et al.",2,[0],[18.23],20.83,26,15,7,[2,2,5,1,1,0,2,1,2,0,0,1,0,1,1,0],"10.1056/NEJMoa066139"],[11889147,"Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes.","J Clin Endocrinol Metab",2002,"Umpierrez et al.",7,[7],[20.77],20.77,13,12,9,[2,1,2,0,1,0,0,1,1,1,0,2,0,0,1,1],"10.1210/jcem.87.3.8341"],[19786670,"Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: results from the randomized phase III TAnDEM study.","J Clin Oncol",2009,"Kaufman et al.",2,[1],[20.77],20.77,15,12,8,[3,2,0,1,0,2,1,0,0,1,1,0,1,0,1,1],"10.1200/JCO.2008.20.6847"],[8782497,"Complications of endoscopic biliary sphincterotomy.","N Engl J Med",1996,"Freeman et al.",5,[4],[16.46],20.76,17,13,8,[2,1,1,2,1,1,3,0,1,1,0,0,1,0,0,0],"10.1056/NEJM199609263351301"],[19213680,"Effect of dronedarone on cardiovascular events in atrial fibrillation.","N Engl J Med",2009,"Hohnloser et al.",2,[0],[20.73],20.73,25,13,9,[2,3,1,2,0,3,1,1,0,1,0,0,0,3,0,0],"10.1056/NEJMoa0803778"],[22922562,"Diagnostic accuracy of fractional flow reserve from anatomic CT angiography.","JAMA",2012,"Min et al.",3,[0],[18.63],20.73,15,13,8,[0,0,1,3,0,2,0,1,1,1,0,2,1,1,0,0],"10.1001/2012.jama.11274"],[23022496,"Incomplete polyp resection during colonoscopy-results of the complete adenoma resection (CARE) study.","Gastroenterology",2013,"Pohl et al.",3,[1,4],[18.66,20.73],20.73,21,15,8,[0,0,1,1,1,2,3,0,1,3,0,0,0,2,1,0],"10.1053/j.gastro.2012.09.043"],[8594426,"Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home. The Tasman Study Group.","N Engl J Med",1996,"Koopman et al.",2,[0],[20.7],20.7,15,14,8,[1,2,4,0,1,0,0,1,0,1,3,0,0,0,0,1],"10.1056/NEJM199603143341102"],[12517231,"Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant.","JAMA",2003,"Brown et al.",5,[2,9,14],[18.66,19.2,4.65],20.7,13,12,8,[0,0,1,0,1,1,4,1,0,2,1,0,0,0,1,0],"10.1001/jama.289.2.203"],[12814980,"Risk factors for venous thromboembolism.","Circulation",2003,"Anderson et al.",6,[0,3],[20.7,6.16],20.7,12,10,9,[0,1,1,1,1,1,1,1,1,1,0,1,0,0,1,0],"10.1161/01.CIR.0000078469.07362.E6"],[17466195,"Standardized colonoscopy reporting and data system: report of the Quality Assurance Task Group of the National Colorectal Cancer Roundtable.","Gastrointest Endosc",2007,"Lieberman et al.",6,[1,4],[19.39,19.39],20.7,13,12,9,[0,1,4,2,0,1,1,0,0,0,1,1,0,1,0,0],"10.1016/j.gie.2006.12.055"],[17846343,"Radiation dose to patients from cardiac diagnostic imaging.","Circulation",2007,"Einstein et al.",6,[0],[20.7],20.7,13,12,9,[1,2,4,1,0,1,1,1,0,0,0,1,0,0,0,0],"10.1161/CIRCULATIONAHA.107.688101"],[19636533,"A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study.","Intensive Care Med",2009,"Preiser et al.",2,[7],[15.78],20.7,16,10,10,[2,1,2,0,1,0,1,1,1,1,1,1,0,1,0,0],"10.1007/s00134-009-1585-2"],[20970847,"Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials.","Lancet",2010,"Rothwell et al.",7,[1,4],[14.44,10.83],20.7,13,12,9,[0,2,3,0,0,1,1,1,0,0,2,1,0,1,0,0],"10.1016/S0140-6736(10)61543-7"],[21618574,"Survival after yttrium-90 resin microsphere radioembolization of hepatocellular carcinoma across Barcelona clinic liver cancer stages: a European evaluation.","Hepatology",2011,"Sangro et al.",5,[1,4],[20.7,20.7],20.7,17,10,11,[0,1,1,0,2,1,2,0,1,0,2,2,1,1,0,1],"10.1002/hep.24451"],[28221866,"Hormonal Maintenance Therapy for Women With Low-Grade Serous Cancer of the Ovary or Peritoneum.","J Clin Oncol",2017,"Gershenson et al.",7,[1,9,7],[18.05,20.7,16.07],20.7,12,12,9,[0,0,0,0,0,0,0,1,4,1,1,0,1,1,2,1],"10.1200/JCO.2016.71.0632"],[30518502,"Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial.","Lancet Oncol",2019,"Locke et al.",3,[1,10],[20.7,20.7],20.7,15,14,8,[0,0,0,0,0,0,0,0,1,1,2,2,3,3,2,1],"10.1016/S1470-2045(18)30864-7"],[30712900,"Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials.","Lancet",2019,"Cholesterol Treatment Trialists' Collabo",0,[0,7],[16.07,12.16],20.7,18,12,11,[0,0,0,0,0,0,0,0,2,2,1,1,1,1,2,2],"10.1016/S0140-6736(18)31942-1"],[21886519,"Patient and plan characteristics affecting abandonment of oral oncolytic prescriptions.","J Oncol Pract",2011,"Streeter et al.",7,[1],[15.93],20.68,50,44,4,[0,0,0,0,1,0,2,3,7,8,3,5,5,4,7,3],"10.1200/JOP.2011.000316"],[10466665,"Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial.","Lancet",1999,"Rembacken et al.",2,[4],[20.63],20.63,11,11,9,[2,2,0,1,1,0,0,1,0,1,1,0,1,1,0,0],"10.1016/s0140-6736(98)06343-0"],[10493476,"Risk factors for aneurysm rupture in patients kept under ultrasound surveillance. 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Final results of the randomized national multicentre trial--PRAGUE-2.","Eur Heart J",2003,"Widimský et al.",2,[0],[20.63],20.63,15,11,9,[0,1,1,0,3,0,1,2,1,0,0,0,0,1,1,1],"10.1016/s0195-668x(02)00468-2"],[15051640,"Value of programmed ventricular stimulation after tetralogy of fallot repair: a multicenter study.","Circulation",2004,"Khairy et al.",3,[0,17],[20.63,10.26],20.63,29,14,7,[0,0,1,2,2,0,1,1,1,1,2,1,0,1,0,2],"10.1161/01.CIR.0000126495.11040.BD"],[15987918,"Capecitabine as adjuvant treatment for stage III colon cancer.","N Engl J Med",2005,"Twelves et al.",2,[1,4],[20.63,20.63],20.63,12,11,9,[2,1,3,1,0,0,1,1,0,1,0,0,1,1,0,0],"10.1056/NEJMoa043116"],[16476868,"Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials.","Arch Intern Med",2006,"Nordmann et al.",0,[0],[12.65],20.63,19,13,8,[3,1,2,2,1,2,0,2,1,0,0,0,1,0,0,0],"10.1001/archinte.166.3.285"],[18095306,"Acute viral hepatitis increases liver stiffness values measured by transient elastography.","Hepatology",2008,"Arena et al.",7,[4],[20.63],20.63,14,11,9,[0,2,0,2,1,1,2,0,0,1,1,1,0,2,0,0],"10.1002/hep.22007"],[19032223,"Liver transplantation for hepatocellular carcinoma: results of down-staging in patients initially outside the Milan selection criteria.","Am J Transplant",2008,"Ravaioli et al.",5,[4,1],[20.63,18.53],20.63,16,11,11,[0,2,1,0,1,0,1,1,1,0,0,2,0,3,1,0],"10.1111/j.1600-6143.2008.02409.x"],[19553649,"Alcoholic hepatitis.","N Engl J Med",2009,"Lucey et al.",6,[4],[20.63],20.63,11,11,9,[0,1,1,1,0,0,0,1,1,3,0,1,1,1,0,0],"10.1056/NEJMra0805786"],[19570764,"Combined versus sequential diuretic treatment of ascites in non-azotaemic patients with cirrhosis: results of an open randomised clinical trial.","Gut",2010,"Angeli et al.",2,[4],[19.2],20.63,12,11,9,[0,1,0,0,1,0,1,2,1,0,2,0,1,2,1,0],"10.1136/gut.2008.176495"],[20170810,"The risk of thromboembolism and need for oral anticoagulation after successful atrial fibrillation ablation.","J Am Coll Cardiol",2010,"Themistoclakis et al.",3,[0],[20.63],20.63,17,11,9,[1,1,3,1,0,2,1,1,0,2,0,0,0,1,0,0],"10.1016/j.jacc.2009.11.039"],[20863953,"The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis.","J Am Coll Cardiol",2010,"Mottillo et al.",0,[0,7],[12.65,10.26],20.63,18,11,9,[2,1,0,3,0,1,0,1,2,0,0,1,0,1,1,0],"10.1016/j.jacc.2010.05.034"],[21768513,"Observational study of the clinical efficacy of voriconazole and its relationship to plasma concentrations in patients.","Antimicrob Agents Chemother",2011,"Troke et al.",0,[2],[18.01],20.63,12,11,9,[0,1,0,2,1,2,1,0,1,0,0,1,0,1,2,0],"10.1128/AAC.01083-10"],[22025591,"Randomized trial comparing 3 approaches to the initial respiratory management of preterm neonates.","Pediatrics",2011,"Dunn et al.",2,[17,3],[17.66,7.47],20.63,13,11,9,[0,0,1,2,3,1,1,0,0,1,1,0,0,0,1,1],"10.1542/peds.2010-3848"],[22271024,"Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review.","Endoscopy",2012,"Repici et al.",1,[4,1],[20.63,17.66],20.63,15,11,11,[0,0,1,1,2,3,1,0,1,1,0,1,0,0,0,1],"10.1055/s-0031-1291448"],[22389113,"Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms.","Br J Surg",2012,"Sweeting et al.",0,[0,13],[20.63,0.0],20.63,15,11,9,[0,0,0,2,0,1,1,1,1,0,0,1,2,2,1,0],"10.1002/bjs.8707"],[22575589,"Adjuvant radiotherapy versus observation alone for patients at risk of lymph-node field relapse after therapeutic lymphadenectomy for melanoma: a randomised trial.","Lancet Oncol",2012,"Burmeister et al.",2,[1,14],[20.63,18.53],20.63,15,11,9,[0,2,1,1,1,4,0,2,0,0,0,2,0,1,1,0],"10.1016/S1470-2045(12)70138-9"],[23213075,"Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial.","Hepatology",2013,"Bañares et al.",2,[4],[20.63],20.63,11,11,9,[0,0,0,0,1,1,1,2,0,1,0,1,1,2,1,0],"10.1002/hep.26185"],[23294500,"Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial.","Lancet",2013,"Burmester et al.",2,[11],[20.63],20.63,12,11,9,[0,0,0,1,2,1,1,2,0,0,0,1,0,1,1,1],"10.1016/S0140-6736(12)61424-X"],[24101169,"Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial.","JAMA",2013,"Boughey et al.",3,[1],[20.63],20.63,14,11,9,[0,0,0,2,2,1,1,0,1,0,2,1,2,2,0,0],"10.1001/jama.2013.278932"],[24583295,"Incidence and causes of sudden death in U.S. college athletes.","J Am Coll Cardiol",2014,"Maron et al.",5,[0],[20.63],20.63,13,11,9,[0,0,0,1,1,2,1,1,1,0,1,0,0,2,0,1],"10.1016/j.jacc.2014.01.041"],[24731674,"Cardiovascular mortality, all-cause mortality, and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the Da Qing Diabetes Prevention Study: a 23-year follow-up study.","Lancet Diabetes Endocrinol",2014,"Li et al.",2,[7,0],[11.05,6.77],20.63,15,11,11,[0,0,0,0,2,2,1,0,1,1,1,1,1,1,0,0],"10.1016/S2213-8587(14)70057-9"],[29791822,"Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome.","N Engl J Med",2018,"Combes et al.",2,[3],[13.47],20.63,12,11,11,[0,0,0,0,0,0,0,1,1,1,1,1,1,2,1,2],"10.1056/NEJMoa1800385"],[27477773,"Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28 randomised trials.","Lancet Diabetes Endocrinol",2016,"Herrington et al.",0,[8],[8.01],20.62,21,14,11,[0,0,0,0,0,0,0,0,3,2,2,0,0,2,2,4],"10.1016/S2213-8587(16)30156-5"],[16750497,"Immediate versus deferred androgen deprivation treatment in patients with node-positive prostate cancer after radical prostatectomy and pelvic 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al.",2,[0],[20.57],20.57,22,14,7,[0,3,0,0,1,2,0,1,1,1,2,0,3,1,0,1],"10.1016/S0140-6736(11)60101-3"],[21939822,"The CT-STAT (Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment) trial.","J Am Coll Cardiol",2011,"Goldstein et al.",2,[0],[20.57],20.57,21,14,7,[0,1,1,4,2,3,1,1,0,1,0,2,1,0,0,0],"10.1016/j.jacc.2011.03.068"],[22931259,"Intermittent androgen suppression for rising PSA level after radiotherapy.","N Engl J Med",2012,"Crook et al.",2,[1,8,9],[20.57,20.57,20.57],20.57,18,12,8,[0,0,4,1,1,1,0,1,0,2,2,3,0,1,0,1],"10.1056/NEJMoa1201546"],[23084481,"Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911).","Lancet",2012,"Bolla et al.",2,[1,8,9],[20.57,20.57,20.57],20.57,14,12,8,[0,0,2,1,1,1,1,1,0,1,2,2,0,1,0,0],"10.1016/S0140-6736(12)61253-7"],[25388828,"Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): a physiological method of increasing apnoea time in patients with difficult airways.","Anaesthesia",2015,"Patel et al.",7,[3],[16.81],20.57,12,12,8,[0,0,0,0,1,1,1,2,0,2,0,1,1,1,1,1],"10.1111/anae.12923"],[1267867,"A classification of fistula-in-ano.","Br J Surg",1976,"Parks et al.",7,[4],[20.55],20.55,11,11,10,[3,0,0,2,1,1,1,0,0,2,0,0,0,0,0,1],"10.1002/bjs.1800630102"],[4027773,"A clinical sign to predict difficult tracheal intubation: a prospective study.","Can Anaesth Soc J",1985,"Mallampati et al.",5,[3],[8.47],20.55,11,11,10,[0,3,1,1,2,0,0,0,1,0,0,1,0,0,2,0],"10.1007/BF03011357"],[7941614,"Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group.","World Health Organ Tech Rep Ser",1994,"",6,[13,7],[17.85,17.85],20.55,12,11,10,[2,0,1,0,1,0,0,0,2,0,3,0,0,0,2,1],""],[8094768,"Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion.","Lancet",1993,"Goldhaber et al.",2,[0,3],[20.55,15.95],20.55,12,11,10,[2,1,0,1,0,0,0,0,2,2,2,0,0,0,2,0],"10.1016/0140-6736(93)90274-k"],[11511139,"Combination therapy with pulse cyclophosphamide plus pulse methylprednisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis.","Ann Intern Med",2001,"Illei et al.",2,[11,8],[20.55,14.06],20.55,13,11,11,[0,4,2,0,1,1,0,0,0,0,1,0,0,2,0,1],"10.7326/0003-4819-135-4-200108210-00009"],[12517230,"Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic.","JAMA",2003,"Redfield et 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al.",5,[4,0,3],[6.2,14.06,12.16],20.55,14,11,10,[3,0,0,2,1,2,0,0,1,1,0,0,0,2,0,0],"10.1002/hep.21431"],[17241863,"Rates of new or missed colorectal cancers after colonoscopy and their risk factors: a population-based analysis.","Gastroenterology",2007,"Bressler et al.",5,[1,4],[20.55,20.55],20.55,11,11,10,[1,4,1,1,0,1,0,1,0,0,0,2,0,0,0,0],"10.1053/j.gastro.2006.10.027"],[17324398,"Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children.","Gastroenterology",2007,"Hyams et al.",2,[4],[17.85],20.55,11,11,10,[0,0,2,3,0,1,1,1,0,0,0,0,0,1,2,0],"10.1053/j.gastro.2006.12.003"],[17956598,"Development of a capsule endoscopy scoring index for small bowel mucosal inflammatory change.","Aliment Pharmacol Ther",2008,"Gralnek et al.",7,[4],[20.55],20.55,11,11,10,[0,0,1,0,2,0,1,1,2,0,1,0,0,0,3,0],"10.1111/j.1365-2036.2007.03556.x"],[17968019,"American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis 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Cardiovascular Health Study Collaborative Research Group.","N Engl J Med",1999,"O'Leary et al.",5,[0,5],[16.54,2.69],20.48,27,15,11,[3,2,4,2,0,1,1,2,0,0,0,0,0,0,0,0],"10.1056/NEJM199901073400103"],[20215456,"Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.","Diabetes Care",2010,"Pop-Busui et al.",5,[7,5,0],[18.42,7.58,9.85],20.43,20,13,8,[2,0,1,2,1,2,1,2,0,2,1,1,0,2,0,0],"10.2337/dc10-0125"],[8432214,"Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial.","Diabetes Care",1993,"Stamler et al.",5,[0,7],[14.13,14.28],20.42,20,11,9,[3,4,0,2,0,0,0,2,0,0,0,1,1,2,1,1],"10.2337/diacare.16.2.434"],[17011942,"Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial.","Lancet",2006,"Nakamura et al.",2,[7,0],[17.26,16.32],20.42,19,13,8,[1,0,0,2,2,0,0,1,3,0,1,2,0,1,0,1],"10.1016/S0140-6736(06)69472-5"],[17300356,"Efficacy and safety of topiramate for the treatment of chronic migraine: a randomized, double-blind, placebo-controlled trial.","Headache",2007,"Silberstein et al.",2,[5],[20.42],20.42,11,11,9,[1,2,1,1,0,0,0,1,0,1,0,0,0,2,1,1],"10.1111/j.1526-4610.2006.00684.x"],[17628647,"The prevalence of food allergy: a meta-analysis.","J Allergy Clin Immunol",2007,"Rona et al.",0,[12],[15.25],20.42,13,13,8,[0,1,1,3,1,2,2,0,0,0,1,0,1,0,1,0],"10.1016/j.jaci.2007.05.026"],[18813037,"Cardiac risk of noncardiac surgery after percutaneous coronary intervention with drug-eluting stents.","Anesthesiology",2008,"Rabbitts et al.",7,[0],[20.42],20.42,17,11,9,[2,3,0,2,1,0,1,0,1,0,0,1,1,1,0,0],"10.1097/ALN.0b013e318186de1c"],[19877063,"Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: thirty-six-month results of a randomized, double-blind, controlled trial.","Arthritis Rheum",2009,"Saag et al.",2,[13,7],[20.42,19.76],20.42,13,11,9,[0,2,0,1,0,1,1,0,1,0,0,1,1,3,1,0],"10.1002/art.24879"],[21681120,"2011 Compendium of Physical Activities: a second update of codes and MET values.","Med Sci Sports Exerc",2011,"Ainsworth et al.",7,[0],[10.87],20.42,16,11,9,[0,0,1,1,0,2,0,0,0,1,2,1,0,3,1,1],"10.1249/MSS.0b013e31821ece12"],[21690468,"Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification.","J Clin Oncol",2011,"Guo et al.",3,[1,14],[20.42,16.23],20.42,14,11,9,[0,4,2,1,1,1,0,0,1,0,0,1,0,2,1,0],"10.1200/JCO.2010.33.9275"],[23883377,"Riociguat for the treatment of chronic thromboembolic pulmonary hypertension.","N Engl J Med",2013,"Ghofrani et al.",2,[0,3],[20.42,20.42],20.42,15,11,9,[0,0,0,1,1,4,1,1,1,2,0,1,0,0,0,1],"10.1056/NEJMoa1209657"],[25409371,"Early versus on-demand nasoenteric tube feeding in acute pancreatitis.","N Engl J Med",2014,"Bakker et al.",2,[4],[17.76],20.42,13,11,9,[0,0,0,0,1,0,0,2,1,1,1,1,0,4,1,1],"10.1056/NEJMoa1404393"],[28648803,"Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial.","Lancet Gastroenterol Hepatol",2017,"Meyer et al.",2,[1,4],[20.42,20.42],20.42,16,11,11,[0,0,0,0,0,0,0,1,1,2,1,2,1,3,2,1],"10.1016/S2468-1253(17)30156-5"],[9218740,"Basal cell carcinoma of the face: surgery or radiotherapy? 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ACE Inhibitor Myocardial Infarction Collaborative Group.","Circulation",1998,"",0,[0],[20.33],20.33,20,13,8,[1,0,2,1,2,0,1,2,0,2,1,0,0,1,1,0],"10.1161/01.cir.97.22.2202"],[14615107,"Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials.","Lancet",2003,"Turnbull et al.",0,[0],[20.33],20.33,20,13,8,[3,2,2,1,2,1,1,1,1,0,0,0,0,0,0,1],"10.1016/s0140-6736(03)14739-3"],[23121439,"Bedside monitoring to adjust antiplatelet therapy for coronary stenting.","N Engl J Med",2012,"Collet et al.",2,[0],[20.33],20.33,19,14,9,[0,0,2,3,1,2,0,3,2,1,1,0,0,0,0,0],"10.1056/NEJMoa1209979"],[15809377,"Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population: follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study.","Circulation",2005,"Sega et al.",7,[0],[20.32],20.32,17,11,8,[1,3,1,1,1,1,0,0,2,1,0,0,0,1,1,2],"10.1161/01.CIR.0000160923.04524.5B"],[19434742,"Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography.","Hepatology",2009,"Masuzaki et al.",5,[4,1,2],[20.32,6.16,1.0],20.32,13,11,8,[1,1,1,1,1,1,1,0,0,0,0,1,1,2,1,0],"10.1002/hep.22870"],[8040759,"Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications Trial. Diabetes Control and Complications Trial Research Group.","J Pediatr",1994,"",2,[7,0,15],[20.31,1.35,0.0],20.31,24,18,7,[3,0,2,9,0,0,0,6,0,1,0,0,1,2,0,0],"10.1016/s0022-3476(94)70190-3"],[10900274,"Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380.","N Engl J Med",2000,"Lieberman et al.",7,[1,4],[19.49,20.31],20.31,16,14,8,[0,5,2,0,0,0,1,2,0,1,1,0,0,2,0,0],"10.1056/NEJM200007203430301"],[21254324,"Radiation safety program for the cardiac catheterization laboratory.","Catheter Cardiovasc Interv",2011,"Chambers et al.",6,[13],[11.38],20.31,19,14,7,[1,3,2,2,1,1,0,1,0,1,0,1,1,0,1,0],"10.1002/ccd.22867"],[8873514,"Cost-effectiveness of screening for detection of small hepatocellular carcinoma in western patients with Child-Pugh class A cirrhosis.","Am J Med",1996,"Sarasin et al.",7,[4,1],[20.25,15.97],20.25,17,12,10,[0,3,0,0,0,1,0,2,1,2,0,1,1,1,1,1],"10.1016/S0002-9343(96)00197-0"],[11784875,"Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer.","N Engl J Med",2002,"Schiller et al.",2,[1,3],[20.25,18.1],20.25,14,10,10,[3,2,1,2,1,0,0,1,1,1,0,0,1,0,1,0],"10.1056/NEJMoa011954"],[14999696,"Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial.","Hepatology",2004,"Lindor et al.",2,[4],[20.25],20.25,16,10,11,[0,2,1,1,1,1,1,1,0,0,1,1,0,1,0,0],"10.1002/hep.20092"],[16868539,"Adjuvant chemotherapy vs radiotherapy in high-risk endometrial carcinoma: results of a randomised trial.","Br J Cancer",2006,"Maggi et al.",2,[1,9,7],[20.25,20.25,1.0],20.25,16,10,9,[1,2,1,3,0,1,2,0,0,0,1,2,1,0,1,0],"10.1038/sj.bjc.6603279"],[17338776,"Screening, prevention and treatment of viral hepatitis B reactivation in patients with haematological malignancies.","Br J Haematol",2007,"Lalazar et al.",6,[2,4,1],[14.28,11.84,6.47],20.25,14,10,10,[1,1,2,1,1,2,0,1,1,0,0,0,0,1,1,0],"10.1111/j.1365-2141.2006.06465.x"],[17545185,"Long term results of compression therapy alone versus compression plus surgery in chronic venous ulceration (ESCHAR): randomised controlled trial.","BMJ",2007,"Gohel et al.",2,[0,14],[17.66,9.48],20.25,14,10,9,[2,1,0,1,1,2,0,0,0,1,1,1,0,1,1,0],"10.1136/bmj.39216.542442.BE"],[17719703,"Immediate oral feeding in patients with mild acute pancreatitis is safe and may accelerate recovery--a randomized clinical study.","Clin Nutr",2007,"Eckerwall et al.",2,[4],[20.25],20.25,11,10,9,[0,1,2,0,0,1,0,1,0,1,1,1,0,1,1,1],"10.1016/j.clnu.2007.04.007"],[18038452,"Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markers.","Hepatology",2008,"Guha et al.",7,[4],[17.66],20.25,11,10,9,[0,0,1,1,1,1,1,0,0,1,1,1,1,2,0,0],"10.1002/hep.21984"],[18180210,"A reference standard for the description of osteoporosis.","Bone",2008,"Kanis et al.",6,[7,13],[20.25,20.25],20.25,13,10,9,[2,0,1,0,0,0,1,1,1,0,1,2,0,1,2,1],"10.1016/j.bone.2007.11.001"],[19657121,"A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures.","N Engl J Med",2009,"Buchbinder et al.",2,[13,7],[20.25,7.89],20.25,13,10,9,[2,0,1,3,0,1,1,1,0,1,0,0,1,0,1,1],"10.1056/NEJMoa0900429"],[21431947,"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome.","Clin Auton Res",2011,"Freeman et al.",4,[5,0],[13.81,10.26],20.25,15,10,9,[0,0,1,0,0,0,1,1,1,1,1,1,0,1,1,1],"10.1007/s10286-011-0119-5"],[21449785,"Weight loss, exercise, or both and physical function in obese older adults.","N Engl J Med",2011,"Villareal et al.",2,[7],[18.89],20.25,12,10,9,[0,1,1,0,0,1,0,1,1,1,1,1,3,0,0,1],"10.1056/NEJMoa1008234"],[22440891,"Infection-related hospitalizations are associated with increased mortality in patients with inflammatory bowel diseases.","J Crohns Colitis",2013,"Ananthakrishnan et al.",7,[2,4,3],[1.0,20.25,0.0],20.25,16,10,10,[0,0,1,0,0,0,2,0,1,1,1,2,3,2,1,1],"10.1016/j.crohns.2012.02.015"],[22931316,"MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.","N Engl J Med",2012,"Treon et al.",7,[10,1,0],[20.25,17.66,15.12],20.25,11,10,9,[0,0,1,1,0,1,2,1,1,1,0,1,0,1,0,1],"10.1056/NEJMoa1200710"],[23154075,"RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal.","Int J Radiat Oncol Biol Phys",2013,"Kachnic et al.",3,[1,4],[20.25,19.36],20.25,16,10,9,[0,0,0,1,0,2,2,1,0,0,1,2,1,1,2,1],"10.1016/j.ijrobp.2012.09.023"],[25439694,"Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial.","Lancet Oncol",2014,"Hoskin et al.",2,[1,8,9],[20.25,17.66,17.66],20.25,13,10,9,[0,0,0,0,0,1,1,1,0,2,1,1,2,1,2,1],"10.1016/S1470-2045(14)70474-7"],[19406338,"Coronary computed tomography angiography for early triage of patients with acute chest pain: the ROMICAT (Rule Out Myocardial Infarction using Computer Assisted Tomography) trial.","J Am Coll Cardiol",2009,"Hoffmann et 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Analysis of pooled data from five randomized controlled trials.","Arch Intern Med",1994,"",0,[0,5],[20.19,9.77],20.19,23,14,10,[4,1,3,5,1,0,1,0,0,0,0,0,0,0,0,0],""],[19168529,"A systematic review and meta-analysis of intra-aortic balloon pump therapy in ST-elevation myocardial infarction: should we change the guidelines?","Eur Heart J",2009,"Sjauw et al.",0,[0],[20.15],20.15,22,13,8,[1,4,3,1,3,0,0,1,0,0,0,1,0,0,0,1],"10.1093/eurheartj/ehn602"],[19826129,"Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study.","J Clin Oncol",2009,"Heng et al.",7,[1,8],[20.15,20.15],20.15,19,10,8,[0,1,1,2,0,2,1,2,1,1,0,2,1,3,1,1],"10.1200/JCO.2008.21.4809"],[14729656,"Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH).","BMJ",2004,"Piepoli et al.",0,[0],[20.14],20.14,20,15,9,[2,2,2,1,2,2,0,0,2,1,1,0,0,0,0,0],"10.1136/bmj.37938.645220.EE"],[15477396,"Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin.","Circulation",2004,"Gage et al.",0,[0,5],[15.54,7.48],20.12,18,14,8,[2,5,1,3,0,1,0,2,0,0,0,1,0,0,0,0],"10.1161/01.CIR.0000145172.55640.93"],[25921377,"Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study.","Gastroenterology",2015,"Talley et al.",2,[4],[20.12],20.12,13,13,10,[0,0,0,0,0,0,2,0,0,0,0,2,1,0,7,1],"10.1053/j.gastro.2015.04.020"],[33999547,"Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke.","N Engl J Med",2021,"Whitlock et al.",2,[0,5],[20.12,6.77],20.12,15,13,10,[0,0,0,0,0,0,0,0,0,0,0,1,1,6,3,2],"10.1056/NEJMoa2101897"],[10364029,"Intravenous cyclosporin in ulcerative colitis: a five-year experience.","Am J Gastroenterol",1999,"Cohen et al.",5,[4],[20.11],20.11,14,11,8,[2,1,1,0,1,0,1,2,1,1,0,0,2,1,1,0],"10.1111/j.1572-0241.1999.01149.x"],[15269313,"Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.","N Engl J Med",2004,"Cunningham et al.",2,[1,4],[20.11,20.11],20.11,18,11,8,[2,2,2,3,1,0,1,1,0,1,2,0,2,1,0,0],"10.1056/NEJMoa033025"],[19176443,"Diagnostic performance of computed tomography angiography in peripheral arterial disease: a systematic review and meta-analysis.","JAMA",2009,"Met et al.",0,[0],[20.11],20.11,16,11,8,[1,1,1,1,0,0,1,2,1,0,0,0,1,2,2,1],"10.1001/jama.301.4.415"],[19588333,"Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence.","Cochrane Database Syst Rev",2009,"Mattick et al.",0,[6],[18.99],20.11,15,11,8,[1,1,0,1,0,1,0,1,1,1,0,1,2,0,1,1],"10.1002/14651858.CD002209.pub2"],[20368649,"Gadolinium-enhanced magnetic resonance angiography for pulmonary embolism: a multicenter prospective study (PIOPED III).","Ann Intern Med",2010,"Stein et al.",3,[0,3],[20.11,16.84],20.11,14,11,8,[1,0,1,1,0,1,1,0,1,2,1,2,0,0,1,1],"10.7326/0003-4819-152-7-201004060-00008"],[23964934,"Pazopanib versus sunitinib in metastatic renal-cell carcinoma.","N Engl J Med",2013,"Motzer et al.",2,[1,8],[20.11,17.91],20.11,17,11,8,[0,0,0,2,1,3,1,3,1,1,2,1,1,1,0,0],"10.1056/NEJMoa1303989"],[9647873,"Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography.","N Engl J Med",1998,"Adams et al.",2,[0,10,5],[15.77,9.15,6.32],20.06,15,12,8,[2,3,1,3,1,0,0,2,1,0,0,0,0,1,0,1],"10.1056/NEJM199807023390102"],[16478903,"Development and validation of a prognostic index for 4-year mortality in older adults.","JAMA",2006,"Lee et al.",7,[1],[13.38],20.06,14,12,8,[1,4,0,1,1,1,0,1,1,0,0,0,1,0,1,0],"10.1001/jama.295.7.801"],[18297261,"Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. 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Evidence of major therapeutic activity in the anaplastic variants of these neoplasms.","Cancer",1991,"Moertel et al.",5,[1,4,7],[20.05,12.16,12.16],20.05,12,11,9,[2,1,2,0,1,2,1,0,0,1,0,0,0,1,0,0],"10.1002/1097-0142(19910715)68:2<227::aid-cncr2820680202>3.0.co;2-i"],[7674867,"Nontraumatic sports death in high school and college athletes.","Med Sci Sports Exerc",1995,"Van Camp et al.",7,[0],[18.01],20.05,12,11,9,[2,2,0,1,1,2,1,0,1,0,0,0,0,1,0,0],""],[10840563,"Radiation dose to patients from radiopharmaceuticals (addendum 2 to ICRP publication 53).","Ann ICRP",1998,"",7,[0],[11.58],20.05,11,11,9,[2,0,2,2,0,0,1,0,0,1,1,1,0,0,0,1],"10.1016/s0146-6453(99)00006-8"],[11867780,"Percutaneous abscess drainage in Crohn disease: technical success and short- and long-term outcomes during 14 years.","Radiology",2002,"Gervais et al.",7,[2,4],[2.0,18.01],20.05,13,11,9,[0,1,2,0,1,1,2,2,0,2,0,0,0,0,1,0],"10.1148/radiol.2223010554"],[12668651,"Randomized trial of dose-dense versus conventionally 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Radiation Therapy Oncology Group.","JAMA",1999,"Cooper et al.",2,[1,4],[19.76,19.76],19.76,13,10,10,[2,0,0,1,2,0,0,0,1,0,0,1,1,1,1,1],"10.1001/jama.281.17.1623"],[10639542,"The value of routine preoperative medical testing before cataract surgery. Study of Medical Testing for Cataract Surgery.","N Engl J Med",2000,"Schein et al.",2,[0],[12.65],19.76,17,10,9,[1,0,1,2,2,0,1,1,0,0,0,1,1,2,0,0],"10.1056/NEJM200001203420304"],[10811675,"Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy.","J Clin Oncol",2000,"Shepherd et al.",2,[1,3],[19.76,19.76],19.76,15,10,10,[1,3,2,2,1,0,1,1,2,0,0,0,2,0,0,0],"10.1200/JCO.2000.18.10.2095"],[15479682,"Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine.","Gut",2004,"Kruis et al.",2,[4],[19.76],19.76,12,10,9,[2,2,0,0,1,0,0,1,0,2,1,0,1,1,1,0],"10.1136/gut.2003.037747"],[16282178,"Obstructive sleep apnea as a risk factor for stroke and death.","N Engl J Med",2005,"Yaggi et al.",5,[5,0,3],[17.16,7.97,9.48],19.76,11,10,9,[2,1,1,1,0,1,2,1,1,0,0,0,0,1,0,0],"10.1056/NEJMoa043104"],[16426990,"Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial.","Lancet Neurol",2006,"Bourke et al.",2,[5,7],[7.47,5.29],19.76,12,10,10,[1,1,0,0,0,1,1,0,0,1,0,1,1,3,2,0],"10.1016/S1474-4422(05)70326-4"],[16542288,"Accuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: a systematic review.","Am J Gastroenterol",2006,"Colli et al.",0,[1,4],[19.76,19.76],19.76,17,10,11,[1,1,2,0,1,0,1,0,1,0,2,2,0,0,0,1],"10.1111/j.1572-0241.2006.00467.x"],[16920476,"Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother.","Lancet",2006,"Koren et al.",7,[5],[2.69],19.76,13,10,9,[0,2,0,2,0,0,2,0,1,1,1,2,0,0,1,1],"10.1016/S0140-6736(06)69255-6"],[17054187,"Exercise for overweight or obesity.","Cochrane Database Syst Rev",2006,"Shaw et al.",0,[7],[15.12],19.76,19,10,11,[1,0,2,1,0,2,0,1,1,0,0,1,1,0,0,1],"10.1002/14651858.CD003817.pub3"],[17310052,"Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients.","Ann Intern Med",2007,"Dentali et al.",0,[0,3],[14.63,1.0],19.76,13,10,10,[0,1,2,0,1,2,0,1,0,0,1,1,0,0,1,1],"10.7326/0003-4819-146-4-200702200-00007"],[17311598,"Meta-analysis: cancer risk of low-grade dysplasia in chronic ulcerative colitis.","Aliment Pharmacol Ther",2007,"Thomas et al.",0,[4,1],[19.76,5.29],19.76,13,10,11,[1,0,2,1,3,0,0,1,0,0,1,1,1,1,0,0],"10.1111/j.1365-2036.2007.03241.x"],[17540844,"Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC).","Blood",2007,"Olsen et al.",6,[1,10,14],[17.66,19.76,17.66],19.76,14,10,10,[1,0,2,1,1,0,0,1,2,0,0,0,0,1,3,2],"10.1182/blood-2007-03-055749"],[17919486,"Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study.","Gastroenterology",2007,"Gupta et al.",5,[4,1],[19.76,5.78],19.76,12,10,10,[1,0,2,0,2,0,0,0,0,1,2,0,1,1,1,1],"10.1053/j.gastro.2007.08.001"],[18226581,"Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60).","Lancet Oncol",2008,"Pfreundschuh et al.",2,[1,10],[19.76,19.76],19.76,11,10,9,[1,1,1,0,2,1,1,0,0,0,0,0,1,2,1,0],"10.1016/S1470-2045(08)70002-0"],[18662969,"Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma.","J Clin Oncol",2008,"Marcus et al.",2,[1,10],[19.76,19.76],19.76,14,10,9,[3,1,2,3,0,1,1,0,0,1,1,0,0,0,0,1],"10.1200/JCO.2007.13.5376"],[19188927,"A proposed clinical staging system for obesity.","Int J Obes (Lond)",2009,"Sharma et al.",6,[7],[19.76],19.76,14,10,13,[0,0,1,0,0,0,0,1,1,2,0,1,1,1,2,2],"10.1038/ijo.2009.2"],[19357537,"The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer.","J Thorac Oncol",2009,"Rusch et al.",7,[1,3],[17.16,15.12],19.76,11,10,9,[1,1,1,1,2,1,0,0,0,0,0,0,1,0,1,1],"10.1097/JTO.0b013e3181a0d82e"],[19616235,"The R.E.N.A.L. nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth.","J Urol",2009,"Kutikov et al.",7,[1,8],[19.76,19.76],19.76,14,10,9,[0,0,1,0,0,1,2,2,1,2,0,2,0,2,1,0],"10.1016/j.juro.2009.05.035"],[20620720,"Cardiovascular events during differing hypertension therapies in patients with diabetes.","J Am Coll Cardiol",2010,"Weber et al.",2,[0,7],[16.32,10.68],19.76,16,10,10,[1,1,4,1,0,0,0,0,1,1,0,0,1,1,0,3],"10.1016/j.jacc.2010.02.046"],[20679548,"Intra-arrest transnasal evaporative cooling: a randomized, prehospital, multicenter study (PRINCE: Pre-ROSC IntraNasal Cooling Effectiveness).","Circulation",2010,"Castrén et al.",2,[0],[17.16],19.76,11,10,9,[1,0,0,0,3,0,1,1,0,1,1,1,0,0,1,1],"10.1161/CIRCULATIONAHA.109.931691"],[20683947,"High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial.","Hepatology",2010,"Leuschner et al.",2,[4],[19.76],19.76,15,10,11,[0,2,1,0,1,1,0,1,0,0,1,1,0,1,0,1],"10.1002/hep.23727"],[21200035,"Protection from colorectal cancer after colonoscopy: a population-based, case-control study.","Ann Intern Med",2011,"Brenner et al.",5,[1,4],[19.76,19.76],19.76,15,10,9,[0,2,2,0,1,1,1,1,0,1,1,0,0,1,0,0],"10.7326/0003-4819-154-1-201101040-00004"],[21555692,"Response, survival, and long-term toxicity after therapy with the radiolabeled somatostatin analogue [90Y-DOTA]-TOC in metastasized neuroendocrine cancers.","J Clin Oncol",2011,"Imhof et al.",3,[1],[19.76],19.76,12,10,9,[0,1,1,1,2,2,1,1,0,0,1,0,0,0,1,0],"10.1200/JCO.2010.33.7873"],[22108446,"Efficacy of oral vs. topical, or combined oral and topical 5-aminosalicylates, in Ulcerative Colitis: systematic review and meta-analysis.","Am J Gastroenterol",2012,"Ford et al.",0,[4],[19.76],19.76,12,10,10,[0,0,0,0,1,2,2,2,1,1,0,0,1,1,1,0],"10.1038/ajg.2011.410"],[22326435,"Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial.","Gastroenterology",2012,"Rutgeerts et al.",2,[4],[19.76],19.76,11,10,9,[0,0,1,1,0,0,1,0,2,1,1,0,1,2,1,0],"10.1053/j.gastro.2012.01.035"],[22445259,"Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis.","Lancet Oncol",2012,"Machalek et al.",0,[1,2,9],[17.16,7.47,7.47],19.76,10,10,9,[0,0,0,1,1,1,1,1,0,0,1,0,1,1,2,0],"10.1016/S1470-2045(12)70080-3"],[22494121,"A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis.","N Engl J Med",2012,"Elmunzer et al.",2,[4],[19.76],19.76,14,12,8,[0,0,1,1,2,0,2,0,0,0,0,1,2,1,2,1],"10.1056/NEJMoa1111103"],[22513437,"A diagnostic accuracy meta-analysis of endoanal ultrasound and MRI for perianal fistula assessment.","Dis Colon Rectum",2012,"Siddiqui et al.",0,[4],[19.76],19.76,10,10,9,[0,0,0,2,1,1,0,0,1,1,0,1,0,1,1,1],"10.1097/DCR.0b013e318249d26c"],[22626746,"Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.","Circulation",2012,"Izmirly et al.",5,[11,9,0],[15.12,4.65,1.35],19.76,13,10,9,[0,0,0,0,1,0,1,1,2,1,1,0,1,0,1,3],"10.1161/CIRCULATIONAHA.111.089268"],[22717317,"Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study.","Lancet",2012,"Tonelli et al.",5,[0,7,8],[6.77,13.27,6.16],19.76,16,10,11,[0,0,0,2,0,1,0,1,1,1,1,1,0,1,0,2],"10.1016/S0140-6736(12)60572-8"],[22842618,"Mucosal healing in inflammatory bowel diseases: a systematic review.","Gut",2012,"Neurath et al.",1,[4],[19.76],19.76,11,10,9,[0,0,0,1,1,1,1,0,1,0,2,0,1,2,1,0],"10.1136/gutjnl-2012-302830"],[23332236,"Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a randomised controlled trial.","Lancet",2013,"Smolen et al.",2,[11],[19.76],19.76,13,10,8,[0,0,0,2,1,1,1,2,1,1,1,0,0,1,0,0],"10.1016/S0140-6736(12)61811-X"],[25512453,"Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach-the ALBI grade.","J Clin Oncol",2015,"Johnson et al.",5,[4,1],[19.76,13.08],19.76,13,10,9,[0,0,0,0,0,1,1,1,0,1,1,0,1,1,4,1],"10.1200/JCO.2014.57.9151"],[26347918,"Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial.","Lancet",2015,"Engstrøm et al.",2,[0],[19.76],19.76,17,12,8,[0,0,0,0,0,1,3,2,2,0,1,1,1,2,1,0],"10.1016/s0140-6736(15)60648-1"],[26600191,"Esophageal balloon tamponade versus esophageal stent in controlling acute refractory variceal bleeding: A multicenter randomized, controlled trial.","Hepatology",2016,"Escorsell et al.",2,[4],[19.76],19.76,11,10,9,[0,0,0,0,0,1,2,1,0,2,1,1,0,1,1,1],"10.1002/hep.28360"],[28404092,"Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial.","Lancet Gastroenterol Hepatol",2016,"Buti et al.",2,[2,4],[19.76,15.12],19.76,13,10,9,[0,0,0,0,0,0,2,2,1,2,1,1,0,1,1,1],"10.1016/S2468-1253(16)30107-8"],[15190137,"Noninvasive positive-pressure ventilation for respiratory failure after extubation.","N Engl J Med",2004,"Esteban et al.",2,[3],[19.74],19.74,12,11,10,[1,0,0,1,0,1,4,0,0,3,0,0,0,1,0,0],"10.1056/NEJMoa032736"],[19297556,"Randomized, controlled trial of prednisone, cyclophosphamide, and cyclosporine in lupus membranous nephropathy.","J Am Soc Nephrol",2009,"Austin et al.",2,[11,8],[19.74,14.06],19.74,14,11,11,[0,3,3,0,1,0,0,0,0,0,1,0,0,2,2,0],"10.1681/ASN.2008060665"],[21098770,"Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial.","JAMA",2010,"Annema et al.",2,[1,3],[19.74,17.85],19.74,13,11,10,[0,0,3,1,2,3,0,0,0,0,0,1,0,0,1,0],"10.1001/jama.2010.1705"],[21703206,"A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection.","J Hepatol",2011,"Han et al.",3,[2,4,9],[13.55,17.85,4.04],19.74,12,11,10,[0,4,1,1,0,4,0,0,0,0,1,0,1,0,0,0],"10.1016/j.jhep.2011.02.032"],[21771987,"Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial.","JAMA",2011,"Del Mastro et al.",2,[9,1,7],[5.39,19.74,1.0],19.74,11,11,10,[0,3,3,0,0,2,1,0,0,1,0,1,0,0,0,0],"10.1001/jama.2011.991"],[21802134,"Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews.","Lancet",2011,"Nelson et al.",6,[2,4,6],[17.85,15.95,2.69],19.74,16,11,10,[0,0,0,2,3,4,1,2,0,3,0,0,0,0,0,0],"10.1016/S0140-6736(11)61097-0"],[21903745,"Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410.","J Natl Cancer Inst",2011,"Curran et al.",2,[1,3],[19.74,19.74],19.74,12,11,10,[0,0,2,0,2,0,0,0,0,0,0,2,1,1,4,0],"10.1093/jnci/djr325"],[22579043,"Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study.","Lancet",2012,"Barnett et al.",5,[6],[1.0],19.74,12,11,10,[0,0,0,0,0,3,1,0,1,0,0,2,1,3,0,0],"10.1016/S0140-6736(12)60240-2"],[23299522,"Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients.","Ann Surg",2013,"Fazio et al.",7,[4,1,17],[17.85,0.0,0.0],19.74,12,11,10,[0,0,0,0,1,0,2,2,0,1,0,0,0,3,3,0],"10.1097/SLA.0b013e31827d99a2"],[23339639,"High-frequency oscillation in early acute respiratory distress syndrome.","N Engl J Med",2013,"Ferguson et al.",2,[3],[14.44],19.74,14,11,11,[0,0,0,0,1,0,3,2,2,2,0,2,0,0,0,0],"10.1056/NEJMoa1215554"],[23884793,"Predicting lymph node metastasis in pT1 colorectal cancer: a systematic review of risk factors providing rationale for therapy decisions.","Endoscopy",2013,"Bosch et al.",0,[1,4],[19.74,19.74],19.74,12,11,11,[0,0,0,0,2,0,1,0,1,2,0,3,0,0,2,0],"10.1055/s-0033-1344238"],[24621620,"Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study.","Lancet Oncol",2014,"Yamamoto et al.",5,[1,5],[18.96,8.47],19.74,11,11,10,[0,0,0,1,0,1,0,0,0,1,0,3,0,2,3,0],"10.1016/S1470-2045(14)70061-0"],[26088268,"Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial.","Lancet",2015,"Glund et al.",2,[0],[16.99],19.74,11,11,10,[0,0,0,0,2,4,0,1,0,2,0,0,1,1,0,0],"10.1016/S0140-6736(15)60732-2"],[28219691,"Hepatitis B Reactivation Associated With Immune Suppressive and Biological Modifier Therapies: Current Concepts, Management Strategies, and Future Directions.","Gastroenterology",2017,"Loomba et al.",6,[4,2],[17.85,10.83],19.74,12,11,10,[0,0,0,0,0,0,0,0,2,3,2,1,1,0,3,0],"10.1053/j.gastro.2017.02.009"],[28925994,"Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.","Nat Rev Clin Oncol",2018,"Neelapu et al.",6,[5],[1.9],19.74,14,13,10,[0,0,0,0,0,0,1,1,4,3,0,0,2,3,0,0],"10.1038/nrclinonc.2017.148"],[30561481,"Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.","JAMA",2018,"Busse et al.",0,[6],[3.0],19.74,13,11,10,[0,0,0,0,0,0,0,0,0,2,1,1,4,0,2,1],"10.1001/jama.2018.18472"],[31533906,"Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial.","Lancet",2019,"Agarwal et al.",2,[0],[12.63],19.74,13,11,10,[0,0,0,0,0,0,0,0,0,1,2,1,0,3,3,1],"10.1016/S0140-6736(19)32135-X"],[32749941,"Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From 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J Radiat Oncol Biol Phys",2005,"Wallace et al.",7,[9,7],[7.75,6.2],19.73,10,10,10,[0,0,0,0,1,0,0,1,0,1,2,0,0,2,1,2],"10.1016/j.ijrobp.2004.11.038"],[15992642,"Left ventricular non-compaction: insights from cardiovascular magnetic resonance imaging.","J Am Coll Cardiol",2005,"Petersen et al.",3,[0],[19.73],19.73,11,10,10,[0,0,1,2,0,0,1,1,1,2,2,0,0,0,0,0],"10.1016/j.jacc.2005.03.045"],[16055622,"Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease.","Thorax",2005,"Soler-Cataluña et al.",7,[3],[19.73],19.73,12,12,9,[0,1,1,0,0,0,4,0,0,1,1,0,3,1,0,0],"10.1136/thx.2005.040527"],[16224108,"Early noninvasive ventilation averts extubation failure in patients at risk: a randomized trial.","Am J Respir Crit Care Med",2006,"Ferrer et al.",2,[3],[19.73],19.73,10,10,10,[1,0,1,1,0,1,3,0,0,1,0,0,0,2,0,0],"10.1164/rccm.200505-718OC"],[17105757,"Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia.","N Engl J Med",2006,"Schrier et al.",2,[7],[5.39],19.73,13,10,11,[0,0,2,3,1,1,1,0,1,0,2,0,0,0,0,0],"10.1056/NEJMoa065181"],[17517853,"Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes.","N Engl J Med",2007,"Nissen et al.",0,[0,7],[6.77,12.63],19.73,12,10,10,[0,0,2,2,0,0,2,2,1,1,0,0,0,0,1,0],"10.1056/NEJMoa072761"],[18330140,"Protein and amino acid requirements in human nutrition.","World Health Organ Tech Rep Ser",2007,"Joint WHO/FAO/UNU Expert Consultation",7,[7,8],[13.27,7.75],19.73,10,10,10,[1,0,0,1,1,0,2,0,0,3,0,0,0,1,1,0],""],[18356405,"Efficacy, safety, and tolerability of pregabalin treatment for painful diabetic peripheral neuropathy: findings from seven randomized, controlled trials across a range of doses.","Diabetes Care",2008,"Freeman et al.",7,[5,7],[6.2,9.02],19.73,10,10,10,[2,1,0,1,0,0,0,0,0,1,0,1,0,1,3,0],"10.2337/dc07-2105"],[18579811,"Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty.","N Engl J Med",2008,"Eriksson et al.",2,[0],[19.73],19.73,11,10,10,[1,2,2,0,1,0,1,3,0,1,0,0,0,0,0,0],"10.1056/NEJMoa0800374"],[19139439,"Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction.","J Clin Oncol",2009,"Stahl et al.",2,[1,4],[19.73,19.73],19.73,10,10,10,[3,1,1,0,1,0,0,0,2,1,0,0,0,0,1,0],"10.1200/JCO.2008.17.0506"],[19190316,"Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women.","JAMA",2009,"Bliuc et al.",5,[13,7],[19.73,19.73],19.73,11,10,10,[0,1,1,1,0,0,1,0,0,0,1,3,0,0,3,0],"10.1001/jama.2009.50"],[20218877,"Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.","Clin Infect Dis",2010,"Kontoyiannis et al.",5,[2],[19.73],19.73,11,10,10,[0,1,1,1,0,2,0,2,0,0,1,0,0,0,3,0],"10.1086/651263"],[20525993,"Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia.","N Engl J Med",2010,"Saglio et al.",2,[1,10],[19.73,19.73],19.73,11,10,10,[1,2,2,1,0,2,2,0,0,1,0,0,0,0,0,0],"10.1056/NEJMoa0912614"],[20525995,"Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia.","N Engl J Med",2010,"Kantarjian et al.",2,[1,10],[19.73,19.73],19.73,11,10,10,[1,2,2,1,0,2,2,0,0,1,0,0,0,0,0,0],"10.1056/NEJMoa1002315"],[21335621,"Effect of continuous glucose monitoring on hypoglycemia in type 1 diabetes.","Diabetes Care",2011,"Battelino et al.",2,[7],[19.73],19.73,17,12,7,[1,1,3,0,1,1,1,2,0,1,2,0,1,2,0,0],"10.2337/dc10-1989"],[22585691,"Updated analysis of SWOG-directed intergroup study 0116: a phase III trial of adjuvant radiochemotherapy versus observation after curative gastric cancer resection.","J Clin Oncol",2012,"Smalley et 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al.",2,[1,10,0],[19.4,19.4,18.53],19.4,15,11,8,[2,0,3,2,2,0,1,0,0,2,1,1,0,0,0,1],"10.1056/NEJMoa022340"],[12823149,"Oral beclometasone dipropionate in the treatment of extensive and left-sided active ulcerative colitis: a multicentre randomised study.","Aliment Pharmacol Ther",2003,"Campieri et al.",2,[4],[19.4],19.4,12,11,8,[1,1,1,0,2,0,3,1,0,1,0,0,1,0,1,0],"10.1046/j.1365-2036.2003.01609.x"],[16928994,"Aneurysm syndromes caused by mutations in the TGF-beta receptor.","N Engl J Med",2006,"Loeys et al.",7,[17,0,13],[3.1,19.4,1.0],19.4,15,11,9,[0,1,1,2,0,0,1,0,1,0,0,2,2,2,0,1],"10.1056/NEJMoa055695"],[18753646,"A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy.","N Engl J Med",2008,"Rouse et al.",2,[5],[0.0],19.4,17,11,8,[1,0,1,2,0,4,0,2,2,1,2,1,0,0,0,0],"10.1056/NEJMoa0801187"],[20063276,"Pitfalls of liver stiffness measurement: a 5-year prospective study of 13,369 examinations.","Hepatology",2010,"Castéra et al.",5,[4],[19.4],19.4,12,11,8,[1,0,1,1,1,1,3,0,0,0,1,1,0,1,0,0],"10.1002/hep.23425"],[20180784,"Gastritis OLGA-staging and gastric cancer risk: a twelve-year clinico-pathological follow-up study.","Aliment Pharmacol Ther",2010,"Rugge et al.",7,[4,1],[18.53,12.16],19.4,12,11,8,[0,2,0,1,1,0,1,0,0,0,1,0,1,1,2,1],"10.1111/j.1365-2036.2010.04277.x"],[21044630,"Radioembolization results in longer time-to-progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma.","Gastroenterology",2011,"Salem et al.",7,[1,4],[19.4,19.4],19.4,12,11,8,[1,0,2,0,1,0,1,2,0,1,2,1,0,0,0,1],"10.1053/j.gastro.2010.10.049"],[22143204,"Impact of lymphadenectomy on the oncologic outcome of patients with adrenocortical carcinoma.","Ann Surg",2012,"Reibetanz et al.",5,[1,7],[19.4,19.4],19.4,11,11,8,[0,1,1,0,0,1,1,2,1,1,1,0,2,0,0,0],"10.1097/SLA.0b013e3182367ac3"],[22551104,"A randomized trial of urodynamic testing before stress-incontinence surgery.","N Engl J 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al.",2,[1,5],[19.4,19.4],19.4,12,11,8,[0,0,0,2,1,0,2,1,0,1,2,1,0,0,1,1],"10.1056/NEJMoa1308345"],[7563451,"Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. 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College of Rheumatology provisional criteria for defining clinical inactive disease in select categories of juvenile idiopathic arthritis.","Arthritis Care Res (Hoboken)",2011,"Wallace et al.",5,[11],[19.39],19.39,12,11,9,[0,1,0,0,0,0,0,1,1,0,0,1,0,1,4,2],"10.1002/acr.20497"],[21969502,"Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial.","J Clin Oncol",2011,"Loehrer et al.",2,[1,4,7],[19.39,19.39,19.39],19.39,11,11,9,[0,2,1,2,3,1,1,0,0,0,0,0,0,1,0,0],"10.1200/JCO.2011.34.8904"],[22322237,"Noradrenaline vs. terlipressin in the treatment of hepatorenal syndrome: a randomized study.","J Hepatol",2012,"Singh et al.",2,[4,8],[16.74,10.83],19.39,11,11,9,[0,0,0,0,1,1,0,3,2,0,1,1,0,2,0,0],"10.1016/j.jhep.2012.01.012"],[22541275,"Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of 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advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.","Lancet",2016,"Rosenberg et al.",3,[1,8],[19.39,15.78],19.39,13,11,10,[0,0,0,0,0,1,2,3,2,2,2,1,0,0,0,0],"10.1016/S0140-6736(16)00561-4"],[28146658,"Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer.","N Engl J Med",2017,"Shipley et al.",2,[1,8,9],[19.39,19.39,19.39],19.39,12,11,9,[0,0,0,0,0,0,0,1,1,2,1,2,0,3,0,2],"10.1056/NEJMoa1607529"],[29584549,"Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu.","J Clin Oncol",2018,"Fader et al.",2,[1,9],[19.39,19.39],19.39,12,11,9,[0,0,0,0,0,0,0,0,0,1,1,1,2,1,3,2],"10.1200/JCO.2017.76.5966"],[23343063,"21st-century hazards of smoking and benefits of cessation in the United States.","N Engl J Med",2013,"Jha et 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Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2018.","Diabetes Care",2018,"American Diabetes Association",6,[7],[13.95],19.37,14,12,10,[0,0,0,0,0,0,0,6,1,2,3,0,0,0,0,1],"10.2337/dc18-S002"],[34120185,"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions.","Eur Heart J",2021,"SCORE2-OP working group and ESC Cardiova",7,[0,5],[16.48,0.0],19.37,13,12,9,[0,0,0,0,0,0,0,0,0,0,0,1,1,5,4,2],"10.1093/eurheartj/ehab312"],[8273796,"Intravenous tobramycin and metronidazole as an adjunct to corticosteroids in acute, severe ulcerative colitis.","Am J Gastroenterol",1994,"Mantzaris et al.",2,[4],[19.36],19.36,12,9,10,[1,0,0,0,1,0,1,1,1,1,1,0,2,1,2,0],""],[15078758,"Outcomes in critically ill patients before and after the implementation of an evidence-based nutritional management protocol.","Chest",2004,"Barr et al.",5,[2],[6.2],19.36,12,9,8,[1,0,1,1,1,2,1,0,1,1,1,0,0,0,1,0],"10.1378/chest.125.4.1446"],[15451219,"Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial.","Lancet",2004,"Verweij et al.",0,[1,4],[17.21,14.69],19.36,12,9,9,[0,2,1,2,0,1,1,1,1,0,0,1,1,0,1,0],"10.1016/S0140-6736(04)17098-0"],[17566815,"Glucocorticoid-induced osteoporosis: pathophysiology and therapy.","Osteoporos Int",2007,"Canalis et al.",6,[13,7],[16.79,19.36],19.36,11,9,9,[1,0,1,1,0,1,1,0,1,1,0,0,1,0,1,1],"10.1007/s00198-007-0394-0"],[34534429,"Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer.","N Engl J Med",2021,"Colombo et al.",2,[1,9],[19.33,19.33],19.33,15,12,11,[0,0,0,0,0,0,0,0,0,0,0,0,3,5,4,3],"10.1056/NEJMoa2112435"],[35665782,"Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer.","N Engl J Med",2022,"Modi et al.",2,[1],[17.63],19.33,13,12,11,[0,0,0,0,0,0,0,0,0,0,0,0,2,5,1,4],"10.1056/NEJMoa2203690"],[21502544,"Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status.","J Clin Oncol",2011,"Van Cutsem et al.",2,[1,4],[19.31,17.16],19.31,15,12,7,[1,3,1,2,1,0,1,1,1,0,2,0,0,2,0,0],"10.1200/JCO.2010.33.5091"],[19286178,"Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years.","Gastrointest Endosc",2009,"Cotton et al.",5,[4],[17.26],19.3,13,12,8,[0,2,0,1,0,2,3,0,1,1,0,0,0,0,1,1],"10.1016/j.gie.2008.10.039"],[28212060,"Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma.","N Engl J Med",2017,"Bellmunt et al.",2,[1,8],[17.26,13.18],19.3,18,12,9,[0,0,0,0,0,0,1,2,3,2,3,2,0,3,2,0],"10.1056/NEJMoa1613683"],[28734759,"Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study.","Lancet Oncol",2017,"Overman et al.",2,[1,4],[19.27,17.81],19.27,17,15,7,[0,0,0,0,0,0,0,1,1,4,1,2,5,2,0,1],"10.1016/S1470-2045(17)30422-9"],[26792875,"Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases.","Eur Heart J",2016,"Pinto et al.",4,[0],[17.34],19.24,13,12,9,[0,0,0,0,0,0,2,0,3,2,2,2,0,1,0,0],"10.1093/eurheartj/ehv727"],[29426991,"Post-contrast acute kidney injury - Part 1: Definition, clinical features, incidence, role of contrast medium and risk factors : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines.","Eur Radiol",2018,"van der Molen et al.",6,[8],[8.71],19.24,14,12,9,[0,0,0,0,0,0,0,1,1,6,0,2,0,3,1,0],"10.1007/s00330-017-5246-5"],[2303687,"High-dose methylprednisolone in the treatment of active ulcerative colitis.","J Clin Gastroenterol",1990,"Rosenberg et al.",7,[4],[19.2],19.2,12,10,9,[3,1,0,0,1,0,1,2,0,0,0,0,1,1,2,0],"10.1097/00004836-199002000-00011"],[4015380,"Pancreatic cancer. 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Duration of Anticoagulation Trial Study Group.","N Engl J Med",1995,"Schulman et al.",2,[0,3,11],[19.2,7.97,0.0],19.2,11,10,9,[2,1,1,1,0,0,0,0,1,2,2,0,1,0,0,0],"10.1056/NEJM199506223322501"],[7856680,"Safety of metronidazole in pregnancy: a meta-analysis.","Am J Obstet Gynecol",1995,"Burtin et al.",0,[17],[0.0],19.2,10,10,9,[1,1,0,0,2,1,2,0,0,1,1,0,1,0,0,0],"10.1016/0002-9378(95)90567-7"],[8214998,"The weight-based heparin dosing nomogram compared with a \"standard care\" nomogram. A randomized controlled trial.","Ann Intern Med",1993,"Raschke et al.",2,[0],[14.63],19.2,13,12,8,[2,5,1,0,0,0,0,0,1,1,0,1,0,1,0,1],"10.7326/0003-4819-119-9-199311010-00002"],[8831597,"Surgical resection of hepatocellular carcinoma in cirrhotic patients: prognostic value of preoperative portal pressure.","Gastroenterology",1996,"Bruix et al.",7,[4,1],[19.2,10.26],19.2,12,10,9,[0,1,0,0,0,1,1,1,0,0,2,1,0,1,2,0],"10.1016/s0016-5085(96)70070-7"],[8874456,"Effect of anaemia and cardiovascular disease on surgical mortality and morbidity.","Lancet",1996,"Carson et al.",5,[10,0],[9.77,4.04],19.2,10,10,9,[1,1,1,0,0,2,0,2,0,1,1,0,0,0,1,0],"10.1016/S0140-6736(96)04330-9"],[9174558,"The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. International Stroke Trial Collaborative Group.","Lancet",1997,"",2,[0,5],[19.2,13.81],19.2,11,10,9,[3,1,1,1,0,0,0,2,0,0,1,1,0,1,0,0],""],[9262493,"The acquisition of herpes simplex virus during pregnancy.","N Engl J Med",1997,"Brown et al.",5,[2,9,8],[19.2,19.2,11.4],19.2,12,11,9,[1,1,0,0,1,0,4,0,0,1,1,0,0,0,2,0],"10.1056/NEJM199708213370801"],[9737513,"Impact of atrial fibrillation on the risk of death: the Framingham Heart Study.","Circulation",1998,"Benjamin et al.",5,[0],[19.2],19.2,18,11,10,[1,0,2,1,0,2,3,0,0,0,0,0,0,3,1,0],"10.1161/01.cir.98.10.946"],[9890846,"Physiologic left ventricular cavity dilatation in elite athletes.","Ann Intern Med",1999,"Pelliccia et al.",7,[0,17],[19.2,1.0],19.2,13,11,9,[0,1,1,0,0,0,1,2,3,3,0,0,0,0,1,0],"10.7326/0003-4819-130-1-199901050-00005"],[11320387,"Temporal aspects of heparin-induced thrombocytopenia.","N Engl J Med",2001,"Warkentin et al.",5,[10],[13.38],19.2,12,10,10,[0,2,1,0,1,1,0,2,1,1,0,0,0,0,0,2],"10.1056/NEJM200104263441704"],[11427329,"The Faces Pain Scale-Revised: toward a common metric in pediatric pain measurement.","Pain",2001,"Hicks et al.",7,[],[],19.2,10,10,9,[0,2,1,2,1,0,1,1,0,1,0,0,0,1,0,0],"10.1016/S0304-3959(01)00314-1"],[11907289,"Bosentan therapy for pulmonary arterial hypertension.","N Engl J Med",2002,"Rubin et al.",2,[3,0],[12.63,8.47],19.2,13,10,9,[1,0,1,0,2,2,0,1,1,0,0,0,0,2,0,2],"10.1056/NEJMoa012212"],[11994321,"Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features.","J Clin Endocrinol Metab",2002,"Papini et al.",5,[7,1],[19.2,10.83],19.2,10,10,9,[2,1,1,1,0,2,1,1,0,1,0,0,0,0,0,0],"10.1210/jcem.87.5.8504"],[12000813,"Immediate repair compared with surveillance of small abdominal aortic aneurysms.","N Engl J Med",2002,"Lederle et al.",2,[0],[19.2],19.2,13,10,9,[2,0,0,2,0,1,0,1,1,0,0,1,2,2,0,0],"10.1056/NEJMoa012573"],[12525451,"The radiosensitivity of the human oocyte.","Hum Reprod",2003,"Wallace et al.",5,[1],[11.58],19.2,12,10,9,[0,0,0,0,0,1,0,3,0,0,1,1,1,1,2,1],"10.1093/humrep/deg016"],[12610029,"The diabetes risk score: a practical tool to predict type 2 diabetes risk.","Diabetes Care",2003,"Lindström et al.",5,[7],[18.36],19.2,13,10,9,[1,1,1,2,1,3,1,1,0,0,0,0,0,0,0,0],"10.2337/diacare.26.3.725"],[12614096,"Management of the clinically inapparent adrenal mass (\"incidentaloma\").","Ann Intern Med",2003,"Grumbach et al.",7,[7,1],[19.2,16.6],19.2,11,10,9,[1,0,0,0,0,2,3,1,1,1,0,0,1,0,1,0],"10.7326/0003-4819-138-5-200303040-00013"],[12634667,"A double-blind, randomized, placebo-controlled trial of acyclovir in late pregnancy for the reduction of herpes simplex virus shedding and cesarean delivery.","Am J Obstet Gynecol",2003,"Watts et al.",2,[2,9,8],[19.2,19.2,14.06],19.2,10,10,9,[1,0,0,0,1,1,2,0,0,1,1,0,0,0,2,1],"10.1067/mob.2003.185"],[12939586,"Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators.","Hepatology",2003,"D'Amico et al.",5,[4],[19.2],19.2,13,12,7,[0,1,1,1,0,1,1,1,1,0,2,0,1,0,2,1],"10.1053/jhep.2003.50385"],[14595312,"Complications of enteral access.","Gastrointest Endosc",2003,"McClave et al.",6,[4,2,1],[14.63,11.84,7.22],19.2,12,10,9,[2,1,0,1,0,2,0,0,0,1,1,2,0,1,0,0],"10.1016/s0016-5107(03)02147-3"],[15016485,"Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions.","Lancet",2004,"Collins et al.",2,[0,5],[16.55,12.63],19.2,14,11,9,[2,2,1,2,0,0,0,0,0,0,0,2,0,1,0,1],"10.1016/S0140-6736(04)15690-0"],[15023164,"Meta-analysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer.","Aliment Pharmacol Ther",2004,"Gisbert et al.",0,[4,2],[14.06,6.77],19.2,11,10,9,[1,1,2,0,1,2,1,0,0,2,0,0,0,0,0,1],"10.1111/j.1365-2036.2004.01898.x"],[15096330,"D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review.","Ann Intern Med",2004,"Stein et al.",0,[0,3],[19.2,10.26],19.2,11,10,9,[2,1,0,2,1,1,0,0,1,1,2,0,0,0,0,0],"10.7326/0003-4819-140-8-200404200-00005"],[15268886,"A meta-analysis of previous fracture and subsequent fracture risk.","Bone",2004,"Kanis et al.",0,[13,7],[19.2,19.2],19.2,12,10,9,[1,0,0,0,0,0,1,0,2,0,1,2,1,1,3,0],"10.1016/j.bone.2004.03.024"],[15371578,"Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B.","N Engl J Med",2004,"Marcellin et al.",2,[2,4],[19.2,17.16],19.2,12,10,9,[0,4,2,1,0,1,0,0,1,0,0,1,0,0,1,1],"10.1056/NEJMoa040431"],[15710985,"Small bowel involvement in Crohn's disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis.","Gut",2005,"Voderholzer et al.",5,[4],[19.2],19.2,10,10,9,[0,0,2,2,1,0,1,0,1,1,1,0,0,0,1,0],"10.1136/gut.2004.040055"],[15733628,"Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4).","Pain",2005,"Bouhassira et al.",7,[5,6],[9.02,0.0],19.2,10,10,9,[1,2,0,2,0,0,0,1,1,0,0,0,0,1,1,1],"10.1016/j.pain.2004.12.010"],[16148283,"Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia.","N Engl J Med",2005,"Bucaneve et al.",2,[2,10,1],[13.81,12.63,11.38],19.2,13,10,9,[4,1,1,0,1,1,0,1,0,0,2,0,0,1,0,0],"10.1056/NEJMoa044097"],[16267757,"A significant sex--but not elective cesarean section--effect on mother-to-child transmission of hepatitis C virus infection.","J Infect Dis",2005,"European Paediatric Hepatitis C Virus Ne",5,[2,4,9],[19.2,11.38,5.78],19.2,12,10,9,[0,2,1,3,0,2,0,0,1,1,1,1,0,0,0,0],"10.1086/497695"],[16282177,"Continuous positive airway pressure for central sleep apnea and heart failure.","N Engl J Med",2005,"Bradley et al.",2,[0,3,5],[7.47,8.47,8.47],19.2,14,10,9,[2,1,1,0,0,1,2,0,1,0,0,1,0,0,1,0],"10.1056/NEJMoa051001"],[16780557,"Accuracy of monoclonal stool antigen test for the diagnosis of H. pylori infection: a systematic review and meta-analysis.","Am J Gastroenterol",2006,"Gisbert et al.",0,[2],[17.16],19.2,12,10,10,[0,2,3,1,1,0,1,0,0,1,0,0,0,1,1,0],"10.1111/j.1572-0241.2006.00668.x"],[17003399,"Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review.","JAMA",2006,"Lindor et al.",1,[1,4,7],[19.2,14.63,10.26],19.2,14,10,12,[0,1,1,2,2,1,2,1,0,0,0,0,0,1,0,0],"10.1001/jama.296.12.1507"],[17005948,"Sentinel-node biopsy or nodal observation in melanoma.","N Engl J Med",2006,"Morton et al.",2,[1,14],[19.2,19.2],19.2,17,10,9,[2,3,2,0,1,2,0,1,0,0,0,1,0,0,1,0],"10.1056/NEJMoa060992"],[17009270,"Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial.","Arthritis Rheum",2006,"Mazlumzadeh et al.",2,[0,11,5],[19.2,10.83,6.77],19.2,13,10,9,[2,0,0,0,0,1,0,0,1,2,1,1,2,0,0,1],"10.1002/art.22163"],[17286619,"The impact of treatment of portopulmonary hypertension on survival following liver transplantation.","Am J Transplant",2007,"Ashfaq et al.",5,[4,0,3],[11.58,4.65,2.69],19.2,13,10,9,[0,1,1,1,1,3,0,1,0,0,1,0,0,2,0,0],"10.1111/j.1600-6143.2006.01701.x"],[17416853,"Meta-analysis of BRCA1 and BRCA2 penetrance.","J Clin Oncol",2007,"Chen et al.",0,[1,7,9],[19.2,12.16,12.16],19.2,12,10,9,[1,0,0,1,0,0,2,2,0,1,1,0,0,1,2,0],"10.1200/JCO.2006.09.1066"],[17460505,"Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America.","J Pediatr Gastroenterol Nutr",2007,"Bousvaros 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episodic to chronic migraine: a longitudinal population-based study.","Headache",2008,"Bigal et al.",5,[5],[19.2],19.2,10,10,9,[1,1,1,1,0,0,0,0,2,1,0,0,0,1,2,0],"10.1111/j.1526-4610.2008.01217.x"],[19006537,"Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome--results of two randomized, placebo-controlled studies.","Aliment Pharmacol Ther",2009,"Drossman et al.",2,[4],[17.16],19.2,10,10,9,[2,0,0,0,1,0,1,1,0,0,1,1,1,0,2,0],"10.1111/j.1365-2036.2008.03881.x"],[19093923,"Effective exercise for the prevention of falls: a systematic review and meta-analysis.","J Am Geriatr Soc",2008,"Sherrington et al.",0,[13,7],[10.26,8.37],19.2,11,10,9,[2,0,1,1,1,2,1,2,0,1,0,0,0,0,0,0],"10.1111/j.1532-5415.2008.02014.x"],[19118302,"Decontamination of the digestive tract and oropharynx in ICU patients.","N Engl J Med",2009,"de Smet et al.",2,[2],[17.16],19.2,12,10,9,[1,1,1,2,0,2,1,1,1,0,0,0,0,0,0,0],"10.1056/NEJMoa0800394"],[19196866,"International prognostic 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al.",2,[3,2],[19.2,13.81],19.2,13,10,10,[1,1,1,0,1,0,3,0,0,0,1,0,0,1,1,0],"10.1001/jama.2009.1297"],[20407061,"Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States.","JAMA",2010,"Siston et al.",7,[2,3,9],[14.48,14.48,4.65],19.2,15,10,8,[1,0,2,1,0,1,1,1,3,1,0,1,0,1,2,0],"10.1001/jama.2010.479"],[20435258,"Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial: An intention-to-treat analysis of amputation-free and overall survival in patients randomized to a bypass surgery-first or a balloon angioplasty-first revascularization strategy.","J Vasc Surg",2010,"Bradbury et al.",2,[0],[18.21],19.2,18,12,7,[2,2,0,1,1,2,1,0,1,0,1,1,0,1,1,0],"10.1016/j.jvs.2010.01.073"],[20652289,"Effect of cesarean section on the risk of perinatal transmission of hepatitis C virus from HCV-RNA+/HIV- mothers: a meta-analysis.","Arch Gynecol Obstet",2011,"Ghamar Chehreh et al.",0,[2,4,9],[17.16,10.83,7.97],19.2,12,10,9,[0,1,1,3,0,2,0,0,1,0,1,1,2,0,0,0],"10.1007/s00404-010-1588-9"],[20671013,"Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis.","BMJ",2010,"Bolland et al.",0,[0,5],[0.0,0.0],19.2,11,10,9,[1,1,2,1,2,1,0,2,0,1,0,0,0,0,0,0],"10.1136/bmj.c3691"],[21366473,"Long-term effects of intensive glucose lowering on cardiovascular outcomes.","N Engl J Med",2011,"Gerstein et al.",2,[0,7],[12.16,13.81],19.2,15,10,9,[1,2,2,1,0,2,2,0,0,0,0,1,0,1,0,0],"10.1056/NEJMoa1006524"],[21382171,"Residual vein obstruction to predict the risk of recurrent venous thromboembolism in patients with deep vein thrombosis: a systematic review and meta-analysis.","J Thromb Haemost",2011,"Carrier et al.",0,[0],[19.2],19.2,10,10,9,[0,2,2,1,0,0,0,1,1,1,1,0,0,1,0,0],"10.1111/j.1538-7836.2011.04254.x"],[21459214,"Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema.","Ophthalmology",2011,"Elman et al.",2,[15,0,7],[14.63,16.6,18.36],19.2,11,10,9,[0,1,1,1,1,3,1,0,1,2,0,0,0,0,0,0],"10.1016/j.ophtha.2010.12.033"],[21540199,"2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis.","Ann Rheum Dis",2011,"Braun et al.",1,[11,13],[18.57,15.17],19.2,13,11,10,[0,1,1,4,0,1,2,0,0,1,1,0,0,0,0,0],"10.1136/ard.2011.151027"],[21617112,"Use of metformin in the setting of mild-to-moderate renal insufficiency.","Diabetes Care",2011,"Lipska et al.",6,[7,8],[17.16,10.16],19.2,11,10,9,[0,2,1,2,1,1,0,0,1,0,0,1,0,1,0,0],"10.2337/dc10-2361"],[22123802,"Helicobacter pylori eradication in functional dyspepsia: HEROES trial.","Arch Intern Med",2011,"Mazzoleni et al.",2,[2],[16.6],19.2,12,10,11,[0,0,2,1,1,0,3,0,0,0,1,1,0,1,0,1],"10.1001/archinternmed.2011.533"],[22271046,"Noninvasive elastography-based assessment of liver fibrosis progression and prognosis in primary biliary cirrhosis.","Hepatology",2012,"Corpechot et al.",5,[4],[19.2],19.2,10,10,9,[0,0,0,0,2,0,2,1,1,0,0,1,0,1,1,1],"10.1002/hep.25599"],[22350786,"Upper gastrointestinal involvement of Crohn's disease: a prospective study on the role of upper endoscopy in the diagnostic work-up.","Dig Dis Sci",2012,"Annunziata et al.",5,[4],[19.2],19.2,11,10,9,[0,0,1,1,1,0,0,1,1,0,0,1,0,1,4,0],"10.1007/s10620-012-2072-0"],[22390914,"MR-IMPACT II: Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary artery disease Trial: perfusion-cardiac magnetic resonance vs. single-photon emission computed tomography for the detection of coronary artery disease: a comparative multicentre, multivendor trial.","Eur Heart J",2013,"Schwitter et al.",3,[0],[19.2],19.2,18,14,8,[0,0,1,4,0,0,2,0,0,1,2,1,1,0,2,0],"10.1093/eurheartj/ehs022"],[22391333,"Elimination diet effectively treats eosinophilic esophagitis in adults; food reintroduction identifies causative factors.","Gastroenterology",2012,"Gonsalves et al.",3,[12,4,10],[15.17,19.2,15.17],19.2,10,10,9,[0,0,0,1,0,0,1,1,0,1,0,1,0,2,2,1],"10.1053/j.gastro.2012.03.001"],[22873530,"Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis.","N Engl J Med",2012,"Fleischmann et al.",2,[11],[19.2],19.2,11,10,9,[0,0,0,1,2,1,1,1,0,0,0,0,0,1,1,2],"10.1056/NEJMoa1109071"],[23436336,"Once-daily budesonide MMX in active, mild-to-moderate ulcerative colitis: results from the randomised CORE II study.","Gut",2014,"Travis et al.",2,[4],[19.2],19.2,13,10,10,[0,0,0,0,1,0,4,1,1,1,0,0,2,1,2,0],"10.1136/gutjnl-2012-304258"],[23471642,"The nutritional management of hepatic encephalopathy in patients with cirrhosis: International Society for Hepatic Encephalopathy and Nitrogen Metabolism Consensus.","Hepatology",2013,"Amodio et al.",4,[4,7,5],[19.2,11.58,7.97],19.2,11,10,9,[0,0,0,1,0,1,0,0,2,0,1,1,1,1,2,0],"10.1002/hep.26370"],[23515142,"Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial.","Lancet",2013,"Gabay et al.",2,[11],[19.2],19.2,11,10,9,[0,0,0,2,1,2,1,1,1,0,0,0,0,1,0,1],"10.1016/S0140-6736(13)60250-0"],[23615461,"Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles.","Lancet",2013,"Cunningham et al.",2,[10,1],[19.2,17.16],19.2,10,10,9,[0,0,1,0,3,1,0,0,0,0,1,0,1,1,1,1],"10.1016/S0140-6736(13)60313-X"],[23853213,"Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review.","Gut",2014,"El-Serag et al.",1,[4],[19.2],19.2,10,10,9,[0,0,0,0,1,1,1,1,0,0,0,1,1,3,1,0],"10.1136/gutjnl-2012-304269"],[24211508,"Efficacy and safety of apixaban in patients after cardioversion for atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation).","J 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patients with type 2 diabetes and kidney disease: a systematic review.","JAMA",2014,"Inzucchi et al.",1,[7,8],[14.63,9.48],19.2,14,10,9,[0,0,0,0,0,1,0,0,1,3,1,2,1,2,0,2],"10.1001/jama.2014.15298"],[25561362,"The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis.","Ann Rheum Dis",2015,"Roubille et al.",0,[11,0,14],[9.02,10.83,2.69],19.2,13,10,11,[0,0,0,0,0,0,2,1,1,1,1,0,1,0,2,1],"10.1136/annrheumdis-2014-206624"],[27084592,"Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapy.","J Hepatol",2016,"Reig et al.",7,[4,1],[19.2,11.38],19.2,14,11,11,[0,0,0,0,0,0,4,3,2,1,1,1,0,0,1,0],"10.1016/j.jhep.2016.04.008"],[27423262,"Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four 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diagnosis of myocardial infarction with sensitive cardiac troponin assays.","N Engl J Med",2009,"Reichlin et al.",3,[0],[18.98],18.98,17,11,7,[2,0,2,1,1,1,1,1,1,1,0,1,0,1,1,0],"10.1056/NEJMoa0900428"],[1310159,"Streptozocin-doxorubicin, streptozocin-fluorouracil or chlorozotocin in the treatment of advanced islet-cell carcinoma.","N Engl J Med",1992,"Moertel et al.",3,[1,4,7],[18.96,13.27,13.27],18.96,11,10,10,[0,2,3,1,3,1,1,0,0,0,0,0,0,0,0,0],"10.1056/NEJM199202203260804"],[8709780,"Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT). Italian Study on Complications of Oral Anticoagulant Therapy.","Lancet",1996,"Palareti et al.",5,[0],[18.96],18.96,11,10,11,[1,2,3,0,0,2,0,0,0,0,0,0,0,1,1,0],"10.1016/s0140-6736(96)01109-9"],[10507956,"Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome.","Ann Intern Med",1999,"Netzer et al.",7,[5,3],[16.24,11.85],18.96,10,10,10,[0,0,0,3,0,1,3,0,0,0,0,1,1,1,0,0],"10.7326/0003-4819-131-7-199910050-00002"],[15726661,"Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests.","Hepatology",2005,"Tripodi et al.",7,[4],[17.06],18.96,11,10,10,[0,0,0,0,0,0,0,0,2,2,2,0,0,1,2,1],"10.1002/hep.20569"],[16505659,"A bedside scoring system (\"Candida score\") for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization.","Crit Care Med",2006,"León et al.",5,[2],[18.96],18.96,15,12,10,[2,1,4,1,0,3,1,0,0,0,0,0,0,0,0,0],"10.1097/01.CCM.0000202208.37364.7D"],[18505951,"Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial.","JAMA",2008,"Parienti et al.",2,[2],[13.55],18.96,11,10,11,[1,3,1,3,0,0,1,0,0,1,0,0,0,0,0,0],"10.1001/jama.299.20.2413"],[18559702,"Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis.","Circulation",2008,"Chen et al.",0,[0],[18.96],18.96,10,10,10,[0,0,0,0,0,2,1,3,1,2,0,0,0,1,0,0],"10.1161/CIRCULATIONAHA.107.730366"],[19179316,"Weight loss to treat urinary incontinence in overweight and obese women.","N Engl J Med",2009,"Subak et al.",2,[7,8],[2.69,15.17],18.96,13,10,10,[0,1,0,2,1,3,0,2,0,0,1,0,0,0,0,0],"10.1056/NEJMoa0806375"],[19339719,"HPV screening for cervical cancer in rural India.","N Engl J Med",2009,"Sankaranarayanan et al.",2,[9,1,2],[17.06,18.96,2.69],18.96,10,10,10,[0,2,2,0,2,1,0,1,0,2,0,0,0,0,0,0],"10.1056/NEJMoa0808516"],[19586656,"Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women.","Lancet",2009,"Paavonen et al.",2,[9,1,2],[11.85,7.75,10.83],18.96,12,10,11,[1,4,1,2,0,0,2,0,0,1,0,0,0,0,0,0],"10.1016/S0140-6736(09)61248-4"],[19620161,"Predicting deep venous thrombosis in pregnancy: out in \"LEFt\" field?","Ann Intern Med",2009,"Chan et al.",5,[0,9,10],[18.96,10.83,1.0],18.96,11,10,10,[2,3,0,1,0,1,0,2,0,0,2,0,0,0,0,0],"10.7326/0003-4819-151-2-200907210-00004"],[20149473,"Clinical outcomes of radiofrequency ablation, percutaneous alcohol and acetic acid injection for hepatocelullar carcinoma: a meta-analysis.","J Hepatol",2010,"Germani et al.",0,[1,4],[18.96,18.96],18.96,12,10,10,[0,2,2,0,0,2,1,2,0,0,0,0,0,1,0,0],"10.1016/j.jhep.2009.12.004"],[20483497,"Semiannual surveillance is superior to annual surveillance for the detection of early hepatocellular carcinoma and patient survival.","J Hepatol",2010,"Santi et al.",7,[4,1],[18.96,13.27],18.96,13,10,12,[0,2,1,0,0,1,0,0,1,0,0,2,0,0,0,4],"10.1016/j.jhep.2010.03.010"],[21542742,"Radical prostatectomy versus watchful waiting in early prostate cancer.","N Engl J Med",2011,"Bill-Axelson et al.",2,[1,8,9],[18.96,18.96,18.96],18.96,13,12,8,[0,1,5,3,0,0,1,2,0,0,0,1,0,0,0,0],"10.1056/NEJMoa1011967"],[21873632,"Impact of preoperative maintenance or interruption of aspirin on thrombotic and bleeding events after elective non-cardiac surgery: the multicentre, randomized, blinded, placebo-controlled, STRATAGEM trial.","Br J Anaesth",2011,"Mantz et al.",2,[0],[13.27],18.96,14,10,11,[0,2,0,0,0,0,1,1,2,0,0,3,2,0,0,0],"10.1093/bja/aer274"],[22653260,"Cholangiocarcinoma and dominant strictures in patients with primary sclerosing cholangitis: a 25-year single-centre experience.","Eur J Gastroenterol Hepatol",2012,"Chapman et al.",7,[4,1],[18.96,6.2],18.96,10,10,10,[0,0,0,0,2,0,2,1,2,0,0,2,0,0,0,1],"10.1097/MEG.0b013e3283554bbf"],[24150027,"Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.","Obstet Gynecol",2013,"",4,[0,9],[17.06,11.85],18.96,11,10,10,[0,0,0,1,0,3,0,3,1,1,0,0,0,1,0,0],"10.1097/01.AOG.0000437382.03963.88"],[24183638,"Executive summary of the 2013 International Society for Clinical Densitometry Position Development Conference on bone densitometry.","J Clin Densitom",2013,"Schousboe et al.",6,[7,13],[16.24,16.24],18.96,11,10,10,[0,0,0,1,0,3,2,0,2,2,0,0,0,0,1,0],"10.1016/j.jocd.2013.08.004"],[24401022,"Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions.","N Engl J Med",2014,"Goede et al.",2,[1,10],[16.24,14.44],18.96,11,10,10,[0,0,0,0,2,0,3,3,0,0,1,0,1,1,0,0],"10.1056/NEJMoa1313984"],[26639149,"Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia.","N Engl J Med",2015,"Burger et al.",2,[1,10],[18.96,18.96],18.96,10,10,10,[0,0,0,0,0,0,2,3,0,0,0,2,0,1,1,1],"10.1056/NEJMoa1509388"],[27706464,"Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation on Reintubation and Postextubation Respiratory Failure in High-Risk Patients: A Randomized Clinical Trial.","JAMA",2016,"Hernández et al.",2,[3],[16.24],18.96,11,10,10,[0,0,0,0,0,0,1,1,0,3,1,1,0,3,0,0],"10.1001/jama.2016.14194"],[28681500,"Continuous support for women during childbirth.","Cochrane Database Syst Rev",2017,"Bohren et al.",1,[9,17],[6.77,4.04],18.96,18,12,10,[0,0,0,0,0,0,0,2,0,3,0,3,0,2,1,2],"10.1002/14651858.CD003766.pub6"],[29405274,"Randomized clinical trial of adjuvant gemcitabine chemotherapy versus observation in resected bile duct cancer.","Br J Surg",2018,"Ebata et al.",2,[1,4],[18.96,18.96],18.96,10,10,10,[0,0,0,0,0,0,0,0,1,1,1,0,2,2,3,0],"10.1002/bjs.10776"],[15135594,"Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial.","Lancet",2004,"Halliday et al.",2,[0,5],[18.95,14.92],18.95,24,13,7,[4,2,3,3,0,0,1,1,0,0,0,1,0,2,0,0],"10.1016/S0140-6736(04)16146-1"],[19297566,"Screening and prostate-cancer mortality in a randomized European study.","N Engl J Med",2009,"Schröder et al.",2,[1,8,9],[18.91,18.91,18.91],18.91,15,13,8,[1,2,6,3,2,1,0,0,0,0,0,0,0,0,0,0],"10.1056/NEJMoa0810084"],[4441827,"Azathioprine in ulcerative colitis: final report on controlled therapeutic trial.","Br Med J",1974,"Jewell et al.",2,[4],[18.89],18.89,11,9,9,[2,1,0,1,2,0,0,0,1,1,0,0,1,1,1,0],"10.1136/bmj.4.5945.627"],[4830803,"Combined therapy for cancer of the anal canal: a preliminary report.","Dis Colon Rectum",1974,"Nigro et al.",7,[1,4],[18.89,18.89],18.89,13,9,9,[0,0,1,1,0,0,1,2,0,0,1,0,1,1,2,1],"10.1007/BF02586980"],[10770301,"Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial.","Lancet",2000,"Berge et al.",2,[0,5],[18.89,18.89],18.89,10,9,9,[1,2,1,1,1,0,1,1,0,0,0,1,0,0,0,1],"10.1016/s0140-6736(00)02085-7"],[10856094,"Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.","J Clin Oncol",2000,"Fossella et al.",2,[1,3],[18.89,18.89],18.89,12,9,10,[1,2,1,0,1,0,1,1,2,0,0,0,2,1,0,0],"10.1200/JCO.2000.18.12.2354"],[11521989,"A prospective randomized controlled trial of intravenous ciprofloxacin as an adjunct to corticosteroids in acute, severe ulcerative colitis.","Scand J Gastroenterol",2001,"Mantzaris et al.",2,[4],[18.89],18.89,11,9,9,[1,0,0,0,1,0,1,1,1,1,1,0,1,0,3,0],"10.1080/003655201750305503"],[12403875,"A systematic review of the use of opioids in the management of dyspnoea.","Thorax",2002,"Jennings et al.",0,[3],[12.59],18.89,14,11,9,[1,3,0,1,0,2,2,1,0,0,1,1,1,0,0,0],"10.1136/thorax.57.11.939"],[12720118,"Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia.","Semin Oncol",2003,"Owen et al.",4,[0,1,10],[18.89,18.89,18.89],18.89,11,9,9,[0,1,3,1,0,0,1,1,0,1,0,1,0,1,0,1],"10.1053/sonc.2003.50082"],[12759473,"Small hepatocellular carcinoma in cirrhosis: randomized comparison of radio-frequency thermal ablation versus percutaneous ethanol injection.","Radiology",2003,"Lencioni et al.",2,[4,1],[18.89,18.89],18.89,18,9,10,[0,2,0,0,2,2,1,0,1,0,1,1,1,2,0,0],"10.1148/radiol.2281020718"],[15235870,"Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaborative study.","J Gastroenterol",2004,"Kitajima et al.",7,[1,4],[18.89,18.89],18.89,14,9,10,[0,2,1,1,3,0,1,1,0,2,0,0,0,1,1,0],"10.1007/s00535-004-1339-4"],[16012942,"A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma.","Gastroenterology",2005,"Shiina et al.",2,[1,4],[18.89,18.89],18.89,19,9,10,[0,1,0,0,2,3,1,0,1,0,1,2,1,2,0,0],"10.1053/j.gastro.2005.04.009"],[16440357,"A randomized controlled study of preemptive lamivudine in patients receiving transarterial chemo-lipiodolization.","Hepatology",2006,"Jang et al.",2,[4,1,2],[16.79,3.39,14.28],18.89,16,9,10,[0,2,0,0,1,2,0,1,2,1,1,2,0,0,1,0],"10.1002/hep.21024"],[16721226,"Early enteral nutrition in severe acute pancreatitis: a prospective randomized controlled trial comparing nasojejunal and nasogastric routes.","J Clin Gastroenterol",2006,"Kumar et al.",2,[4],[18.89],18.89,11,9,9,[1,1,1,0,1,1,0,2,0,1,0,0,0,1,0,1],"10.1097/00004836-200605000-00013"],[18513271,"A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients.","Am J Gastroenterol",2008,"Nguyen et al.",5,[4,2],[14.28,4.04],18.89,11,9,9,[1,0,0,1,1,0,0,1,0,0,1,0,1,2,1,2],"10.1111/j.1572-0241.2007.01780.x"],[18719619,"Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: a case-control study.","Clin Pharmacol Ther",2009,"Madadi et al.",5,[6],[5.08],18.89,13,9,10,[1,2,0,1,1,1,1,0,0,0,1,2,1,0,0,0],"10.1038/clpt.2008.157"],[18809609,"Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study.","J Clin Oncol",2008,"Penel et al.",3,[1,14],[16.32,1.0],18.89,12,9,9,[0,1,1,1,1,2,0,1,0,0,1,0,0,1,3,0],"10.1200/JCO.2008.17.3146"],[19339714,"Effect of early versus deferred antiretroviral therapy for HIV on survival.","N Engl J Med",2009,"Kitahata et al.",7,[2,12,9],[18.89,18.89,16.32],18.89,14,9,9,[2,3,2,2,1,1,1,0,1,0,1,0,0,0,0,0],"10.1056/NEJMoa0807252"],[20488299,"Prevention of atrial fibrillation by Renin-Angiotensin system inhibition a meta-analysis.","J Am Coll Cardiol",2010,"Schneider et al.",0,[0],[18.89],18.89,21,9,10,[1,0,2,1,0,2,1,0,1,0,0,1,0,2,0,1],"10.1016/j.jacc.2010.01.043"],[21333599,"Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial.","Lancet Oncol",2011,"Berenson et al.",2,[13,1],[6.77,13.81],18.89,13,9,9,[0,0,2,3,1,1,0,1,1,0,0,0,1,1,2,0],"10.1016/S1470-2045(11)70008-0"],[21497551,"Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score.","Lancet Oncol",2011,"Yang et al.",7,[4,1,2],[18.89,9.48,9.48],18.89,11,9,9,[0,1,0,0,0,2,0,0,1,0,1,2,1,1,1,1],"10.1016/S1470-2045(11)70077-8"],[21597360,"Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study).","Ann Surg",2011,"Vlug et al.",2,[1,4],[4.65,12.59],18.89,14,9,9,[0,1,1,1,1,0,2,0,0,0,1,0,1,3,1,0],"10.1097/SLA.0b013e31821fd1ce"],[22453568,"One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial.","JAMA",2012,"Joensuu et al.",2,[1,4],[18.89,18.89],18.89,10,9,9,[0,1,1,1,0,0,1,0,1,0,1,0,1,1,2,0],"10.1001/jama.2012.347"],[22761409,"The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: a randomized controlled trial.","Clin Infect Dis",2012,"Park et al.",2,[2],[16.32],18.89,10,9,9,[0,0,0,2,1,1,1,1,1,0,1,1,1,0,0,0],"10.1093/cid/cis599"],[23163728,"Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery.","J Intern Med",2013,"Sjöström",6,[7,0,5],[12.24,4.65,4.65],18.89,12,11,8,[0,0,1,2,1,2,0,2,1,0,1,0,1,1,0,0],"10.1111/joim.12012"],[25470694,"First-line crizotinib versus chemotherapy in ALK-positive lung cancer.","N Engl J Med",2014,"Solomon et al.",2,[1,3],[18.89,16.79],18.89,12,9,10,[0,0,0,0,1,0,0,1,2,1,0,2,2,1,1,1],"10.1056/NEJMoa1408440"],[26633184,"Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders.","JAMA Oncol",2016,"Johnson et 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al.",2,[0],[12.44],18.86,23,12,8,[2,2,3,0,1,3,1,0,2,0,0,0,0,0,0,0],"10.1016/S0140-6736(08)61239-8"],[20214409,"Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study.","Clin Pharmacokinet",2010,"Stangier et al.",3,[8],[0.0],18.86,16,12,9,[0,0,4,2,2,0,0,3,0,1,0,0,0,1,0,1],"10.2165/11318170-000000000-00000"],[20431381,"A randomized, double-blind, multicenter study of caspofungin versus liposomal amphotericin B for empiric antifungal therapy in pediatric patients with persistent fever and neutropenia.","Pediatr Infect Dis J",2010,"Maertens et al.",2,[10],[7.47],18.86,13,12,8,[3,3,2,1,1,0,0,0,1,0,0,0,1,0,0,0],"10.1097/INF.0b013e3181da2171"],[28000140,"Flash Glucose-Sensing Technology as a Replacement for Blood Glucose Monitoring for the Management of Insulin-Treated Type 2 Diabetes: a Multicenter, Open-Label Randomized Controlled Trial.","Diabetes Ther",2017,"Haak et al.",7,[7],[18.86],18.86,14,12,8,[0,0,0,0,0,0,0,0,2,1,2,1,3,1,0,3],"10.1007/s13300-016-0223-6"],[28592387,"Dabrafenib plus trametinib in patients with BRAFV600-mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial.","Lancet Oncol",2017,"Davies et al.",3,[1,14,5],[18.86,12.32,6.73],18.86,14,12,8,[0,0,0,0,0,0,0,0,1,2,2,5,1,1,2,0],"10.1016/S1470-2045(17)30429-1"],[7778826,"Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis.","Ann Intern Med",1995,"Pearson et al.",0,[4],[18.85],18.85,11,11,8,[2,1,1,2,0,0,1,2,0,1,0,0,0,0,0,1],"10.7326/0003-4819-123-2-199507150-00009"],[10500056,"Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.","Gastroenterology",1999,"Rutgeerts et al.",2,[4],[18.85],18.85,12,11,8,[1,1,2,1,0,0,2,1,0,0,0,0,0,2,2,0],"10.1016/s0016-5085(99)70332-x"],[11910338,"The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota.","Gastroenterology",2002,"Schwartz et al.",5,[4],[18.85],18.85,12,11,8,[1,0,0,1,0,1,2,2,1,1,0,0,0,0,3,0],"10.1053/gast.2002.32362"],[12093772,"Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.","Circulation",2002,"Priori et al.",7,[0],[18.85],18.85,20,11,8,[0,1,1,0,1,0,2,1,2,0,2,0,0,1,0,0],"10.1161/01.cir.0000020013.73106.d8"],[12118019,"Combined-modality treatment and selective organ preservation in 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al.",7,[17],[0.0],18.36,9,9,9,[0,0,0,0,1,1,1,0,0,1,2,0,1,1,1,0],"10.1002/bdra.20013"],[15256427,"Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance.","Blood",2005,"St Pierre et al.",3,[7],[9.02],18.36,10,9,10,[2,0,2,0,1,1,0,0,0,1,1,1,1,0,0,0],"10.1182/blood-2004-01-0177"],[15536109,"Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial.","JAMA",2004,"Bakris et al.",2,[0,7],[14.28,8.47],18.36,16,9,9,[0,1,1,0,0,1,0,0,2,1,1,0,0,2,0,1],"10.1001/jama.292.18.2227"],[15728164,"Effects of estrogen with and without progestin on urinary incontinence.","JAMA",2005,"Hendrix et al.",7,[8],[8.47],18.36,12,9,9,[0,1,1,1,3,0,2,2,0,0,1,0,0,0,1,0],"10.1001/jama.293.8.935"],[15728810,"Recombinant activated factor VII for acute intracerebral hemorrhage.","N Engl J Med",2005,"Mayer et al.",2,[0,5],[18.36,9.48],18.36,10,9,9,[1,1,0,0,1,0,0,1,0,0,2,2,0,1,1,0],"10.1056/NEJMoa042991"],[16084255,"Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomised controlled trial.","Lancet",2005,"Harvey et al.",2,[],[],18.36,12,9,9,[0,1,2,0,0,0,1,1,2,0,1,0,0,0,1,1],"10.1016/S0140-6736(05)67061-4"],[16185307,"A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating.","Neurogastroenterol Motil",2005,"Kim et al.",2,[4],[18.36],18.36,11,9,9,[3,1,1,0,1,1,0,1,0,1,0,0,0,0,1,0],"10.1111/j.1365-2982.2005.00695.x"],[16306520,"High-dose acetylcysteine in idiopathic pulmonary fibrosis.","N Engl J Med",2005,"Demedts et al.",2,[3],[18.36],18.36,11,9,10,[1,2,1,0,2,1,2,0,0,0,0,0,1,1,0,0],"10.1056/NEJMoa042976"],[16530513,"Excellent long-term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid.","Gastroenterology",2006,"Parés et al.",7,[4],[18.36],18.36,9,9,9,[0,1,0,0,1,0,1,1,1,1,0,1,0,0,0,2],"10.1053/j.gastro.2005.12.029"],[16537875,"Effect of routine clopidogrel use on bleeding complications after transbronchial biopsy in humans.","Chest",2006,"Ernst et al.",5,[0],[11.38],18.36,11,9,9,[1,2,2,1,0,1,0,1,0,0,0,1,0,0,0,1],"10.1378/chest.129.3.734"],[16879434,"Elevated serum IgG4 concentration in patients with primary sclerosing cholangitis.","Am J Gastroenterol",2006,"Mendes et al.",5,[4],[18.36],18.36,10,9,9,[0,1,0,0,1,0,1,1,2,2,0,0,0,0,1,1],"10.1111/j.1572-0241.2006.00772.x"],[16885385,"Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients.","Cancer Res",2006,"Hampel et al.",7,[1,4,17],[18.36,16.32,11.84],18.36,10,9,9,[0,1,2,0,0,1,0,0,1,2,1,1,0,0,0,1],"10.1158/0008-5472.CAN-06-1114"],[16941695,"Efficacy of peginterferon alpha-2b in chronic hepatitis delta: relevance of quantitative RT-PCR for follow-up.","Hepatology",2006,"Castelnau et al.",5,[2,4],[18.36,18.36],18.36,11,9,9,[0,2,0,1,0,2,0,1,0,0,1,1,0,0,1,1],"10.1002/hep.21325"],[16983459,"An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.","Osteoporos Int",2006,"Johnell et al.",7,[13,7],[18.36,13.81],18.36,10,9,9,[0,1,2,1,1,0,2,0,1,0,1,1,0,0,0,0],"10.1007/s00198-006-0172-4"],[17719312,"Perindopril preventive treatment on mortality in Duchenne muscular dystrophy: 10 years' follow-up.","Am Heart J",2007,"Duboc et al.",2,[17,5,13],[11.38,9.02,9.02],18.36,9,9,9,[0,0,1,2,1,1,1,0,0,1,1,1,0,0,0,0],"10.1016/j.ahj.2007.05.014"],[18657806,"Palliative treatment with self-expandable metallic stents in patients with advanced type III or IV hilar cholangiocarcinoma: a percutaneous versus endoscopic approach.","Gastrointest Endosc",2009,"Paik et al.",5,[1,4],[16.32,18.36],18.36,11,9,9,[0,2,1,0,1,0,0,0,1,0,1,0,2,1,1,0],"10.1016/j.gie.2008.04.005"],[18809614,"Adjuvant paclitaxel plus carboplatin 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drainage for pancreatic pseudocysts: a prospective randomized trial.","Endoscopy",2009,"Park et al.",2,[4,1],[18.36,6.2],18.36,9,9,9,[0,0,0,0,0,2,1,1,0,0,1,1,0,1,1,1],"10.1055/s-0029-1215133"],[19861953,"The natural history of adult Crohn's disease in population-based cohorts.","Am J Gastroenterol",2010,"Peyrin-Biroulet et al.",5,[4],[18.36],18.36,10,9,9,[0,0,1,2,0,0,2,1,0,1,0,1,0,1,1,0],"10.1038/ajg.2009.579"],[20304589,"Endovascular repair compared with surveillance for patients with small abdominal aortic aneurysms.","J Vasc Surg",2010,"Ouriel et al.",2,[0],[18.36],18.36,12,9,9,[1,0,0,1,0,1,0,1,2,0,0,1,2,2,0,0],"10.1016/j.jvs.2009.10.113"],[20368650,"Systematic review: surveillance for breast cancer in women treated with chest radiation for childhood, adolescent, or young adult cancer.","Ann Intern Med",2010,"Henderson et al.",1,[1,13],[18.36,0.0],18.36,10,9,9,[0,1,1,0,2,1,1,0,1,2,0,0,0,0,1,0],"10.7326/0003-4819-152-7-201004060-00009"],[20415574,"Early versus delayed initiation of antiretroviral therapy for concurrent HIV infection and cryptococcal meningitis in sub-saharan Africa.","Clin Infect Dis",2010,"Makadzange et al.",2,[2,12,9],[18.36,15.78,9.86],18.36,13,9,9,[1,3,4,1,1,0,1,1,0,0,0,0,0,1,0,0],"10.1086/652652"],[20436064,"Early enteral nutrition and outcomes of critically ill patients treated with vasopressors and mechanical ventilation.","Am J Crit Care",2010,"Khalid et al.",5,[2],[9.02],18.36,10,9,9,[0,0,1,1,0,2,1,1,2,0,1,0,1,0,0,0],"10.4037/ajcc2010197"],[20464721,"Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis.","Cochrane Database Syst Rev",2010,"Villatoro et al.",0,[2,4],[1.0,15.78],18.36,9,9,9,[0,1,1,0,1,0,1,2,0,0,1,1,0,0,0,1],"10.1002/14651858.CD002941.pub3"],[20506527,"Safety and efficacy of rituximab in systemic lupus erythematosus: results from 136 patients from the French AutoImmunity and Rituximab registry.","Arthritis Rheum",2010,"Terrier et al.",7,[11,8],[18.36,4.04],18.36,10,9,10,[0,2,1,1,1,1,0,1,1,0,0,0,0,0,1,0],"10.1002/art.27541"],[20512992,"Drug-induced autoimmune hepatitis: clinical characteristics and prognosis.","Hepatology",2010,"Björnsson et al.",7,[4],[18.36],18.36,11,9,9,[1,0,0,0,1,0,1,0,0,2,0,1,2,1,2,0],"10.1002/hep.23588"],[20556748,"Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis.","Cochrane Database Syst Rev",2010,"Holubar et al.",0,[4],[18.36],18.36,11,9,10,[1,1,1,0,1,0,1,3,0,0,0,0,2,1,0,0],"10.1002/14651858.CD001176.pub2"],[20630687,"Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals.","J Vasc Surg",2010,"Kent et al.",5,[0],[18.36],18.36,12,9,9,[0,0,0,1,0,1,1,2,1,0,0,1,2,2,0,0],"10.1016/j.jvs.2010.05.090"],[21175312,"Apixaban versus enoxaparin for thromboprophylaxis after hip replacement.","N Engl J Med",2010,"Lassen et 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al.",0,[0,17],[16.32,7.22],18.36,14,9,9,[0,0,0,1,1,0,0,1,2,0,1,0,1,2,0,1],"10.1016/j.jacc.2011.08.025"],[22184384,"Phase III trial comparing capecitabine plus cisplatin versus capecitabine plus cisplatin with concurrent capecitabine radiotherapy in completely resected gastric cancer with D2 lymph node dissection: the ARTIST trial.","J Clin Oncol",2012,"Lee et al.",2,[1,4],[18.36,18.36],18.36,11,9,9,[0,1,3,1,1,0,0,0,1,0,0,1,0,0,1,2],"10.1200/JCO.2011.39.1953"],[22278337,"Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials.","Diabetologia",2012,"Musso et al.",0,[4,0],[11.38,1.0],18.36,11,9,9,[0,0,1,0,0,0,0,1,1,0,2,0,1,1,2,1],"10.1007/s00125-011-2446-4"],[22571200,"Continuous lenalidomide treatment for newly diagnosed multiple myeloma.","N Engl J Med",2012,"Palumbo et al.",2,[0,1,10],[18.36,18.36,18.36],18.36,13,9,9,[0,0,3,2,1,0,3,0,1,1,1,0,0,0,0,1],"10.1056/NEJMoa1112704"],[22589375,"Immunogenicity and safety of a quadrivalent human papillomavirus vaccine in patients with systemic lupus erythematosus: a case-control study.","Ann Rheum Dis",2013,"Mok et al.",3,[11,2,9],[16.32,6.2,1.0],18.36,12,9,8,[0,0,0,0,1,1,1,0,1,0,2,0,1,1,0,2],"10.1136/annrheumdis-2012-201393"],[23316013,"The ART of decision making: retreatment with transarterial chemoembolization in patients with hepatocellular carcinoma.","Hepatology",2013,"Sieghart et al.",7,[1,4],[18.36,18.36],18.36,12,9,11,[0,0,0,1,2,0,1,2,1,0,0,1,0,1,2,0],"10.1002/hep.26256"],[23514286,"Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.","N Engl J Med",2013,"Carroll et al.",2,[0,5,17],[18.36,13.27,8.47],18.36,10,9,10,[0,0,0,1,0,0,1,1,2,2,1,0,1,1,0,0],"10.1056/NEJMoa1301440"],[23532241,"Effect of azithromycin maintenance treatment on infectious exacerbations among patients with non-cystic fibrosis bronchiectasis: the BAT randomized controlled trial.","JAMA",2013,"Altenburg et al.",2,[3,2],[16.32,5.08],18.36,11,9,10,[0,0,1,0,0,2,2,2,1,0,0,0,0,1,1,1],"10.1001/jama.2013.1937"],[24047060,"Long-term mortality after screening for colorectal cancer.","N Engl J Med",2013,"Shaukat et al.",2,[4,1],[15.78,13.27],18.36,9,9,9,[0,0,0,0,1,2,1,1,0,0,1,0,1,1,1,0],"10.1056/NEJMoa1300720"],[24355641,"Definitions and diagnosis of pulmonary hypertension.","J Am Coll Cardiol",2013,"Hoeper et al.",6,[0,3],[18.36,11.38],18.36,18,9,9,[0,0,0,0,2,1,2,0,2,1,0,0,1,0,1,1],"10.1016/j.jacc.2013.10.032"],[24771492,"The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine.","J Bone Miner Res",2014,"Wright et al.",7,[7,13],[15.78,16.32],18.36,10,9,9,[0,0,0,1,0,1,0,1,2,1,1,2,1,0,0,0],"10.1002/jbmr.2269"],[26301604,"Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in 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Myocardial Infarction.","N Engl J Med",2019,"Tardif et al.",2,[0],[14.7],18.31,14,12,9,[0,0,0,0,0,0,0,0,0,0,2,0,1,4,4,1],"10.1056/NEJMoa1912388"],[23525435,"Exercise training for blood pressure: a systematic review and meta-analysis.","J Am Heart Assoc",2013,"Cornelissen et al.",0,[0],[15.51],18.3,20,14,7,[0,0,0,0,0,2,0,2,4,0,0,0,1,1,2,3],"10.1161/JAHA.112.004473"],[29793631,"Pregnancy Outcomes in Women With Heart Disease: The CARPREG II Study.","J Am Coll Cardiol",2018,"Silversides et al.",5,[0,9],[14.5,10.16],18.3,20,13,8,[0,0,0,0,0,0,0,0,1,0,4,2,3,1,0,2],"10.1016/j.jacc.2018.02.076"],[19161879,"Meta-analysis of the relationship between non-high-density lipoprotein cholesterol reduction and coronary heart disease risk.","J Am Coll Cardiol",2009,"Robinson et al.",0,[0],[10.68],18.29,28,15,8,[5,1,3,2,2,2,1,0,1,0,0,0,0,0,0,0],"10.1016/j.jacc.2008.10.024"],[19371823,"Predictors of coronary stent thrombosis: the Dutch Stent Thrombosis Registry.","J Am Coll Cardiol",2009,"van Werkum et al.",2,[0],[16.25],18.29,18,13,7,[2,0,1,3,0,3,1,2,0,0,1,0,0,1,0,0],"10.1016/j.jacc.2008.12.055"],[20019324,"Heart disease and stroke statistics--2010 update: a report from the American Heart Association.","Circulation",2010,"Lloyd-Jones et al.",7,[0,5],[16.39,3.74],18.29,17,14,8,[5,3,3,0,1,0,0,1,1,0,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.109.192667"],[24004642,"Cessation of dual antiplatelet treatment and cardiac events after percutaneous coronary intervention (PARIS): 2 year results from a prospective observational study.","Lancet",2013,"Mehran et al.",5,[0],[18.29],18.29,21,13,8,[0,0,0,1,1,3,0,4,2,0,0,2,0,0,1,1],"10.1016/S0140-6736(13)61720-1"],[20026778,"Relationship between cardiac rehabilitation and long-term risks of death and myocardial infarction among elderly Medicare beneficiaries.","Circulation",2010,"Hammill et al.",7,[0],[18.27],18.27,28,17,7,[3,3,0,3,2,1,0,1,1,1,0,1,2,0,1,0],"10.1161/CIRCULATIONAHA.109.876383"],[11570939,"Prevention and treatment of postphlebitic syndrome: results of a 3-part study.","Arch Intern Med",2001,"Ginsberg et al.",2,[0],[18.24],18.24,11,11,8,[1,1,2,3,0,0,0,0,0,1,2,1,0,0,0,0],"10.1001/archinte.161.17.2105"],[16758414,"Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study.","Clin Infect Dis",2006,"Garey et al.",5,[2],[18.24],18.24,14,11,9,[2,2,3,1,0,1,0,0,0,0,0,0,0,0,1,1],"10.1086/504810"],[18068515,"Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study.","Lancet",2007,"Addolorato et al.",2,[4,6],[13.73,8.71],18.24,11,11,8,[0,2,1,0,0,1,0,2,1,3,0,0,0,1,0,0],"10.1016/S0140-6736(07)61814-5"],[19153263,"Dry-weight reduction in hypertensive hemodialysis patients (DRIP): a randomized, controlled trial.","Hypertension",2009,"Agarwal et al.",2,[0,8],[12.32,9.77],18.24,13,11,9,[0,2,0,0,2,2,0,0,0,1,1,2,0,0,2,0],"10.1161/HYPERTENSIONAHA.108.125674"],[20200384,"Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults.","N Engl J Med",2010,"Selvin et al.",7,[7,0],[11.58,6.16],18.24,18,11,11,[2,2,3,3,2,1,0,0,0,0,0,0,0,0,0,2],"10.1056/NEJMoa0908359"],[20562694,"Continuous amplitude-integrated electroencephalogram predicts outcome in hypothermia-treated cardiac arrest patients.","Crit Care Med",2010,"Rundgren et al.",5,[0],[16.74],18.24,13,11,8,[0,1,2,0,3,1,0,0,0,0,0,0,2,0,2,1],"10.1097/CCM.0b013e3181eaa1e7"],[21775849,"Timing of indicated late-preterm and early-term birth.","Obstet Gynecol",2011,"Spong et al.",6,[9],[16.05],18.24,18,14,6,[0,1,0,1,1,1,2,3,4,1,4,0,0,0,0,0],"10.1097/AOG.0b013e3182255999"],[23395069,"Outcomes after coronary computed tomography angiography in the emergency department: a systematic review and meta-analysis of randomized, controlled trials.","J Am Coll Cardiol",2013,"Hulten et al.",0,[0],[18.24],18.24,13,11,8,[0,0,0,0,1,3,1,2,0,1,0,3,1,0,0,0],"10.1016/j.jacc.2012.11.061"],[24269926,"Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease.","Gastroenterology",2014,"Feagan et al.",2,[4],[18.24],18.24,11,11,8,[0,0,0,2,1,1,1,0,1,0,0,0,0,3,2,0],"10.1053/j.gastro.2013.11.024"],[25788230,"CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial.","Lancet",2015,"SCOT-HEART investigators",2,[0],[16.26],18.24,16,11,8,[0,0,0,0,0,1,2,2,0,1,2,3,0,2,0,0],"10.1016/S0140-6736(15)60291-4"],[26832656,"High-Resolution Manometry Improves the Diagnosis of Esophageal Motility Disorders in Patients With Dysphagia: A Randomized Multicenter Study.","Am J Gastroenterol",2016,"Roman et al.",2,[4,16],[18.24,2.69],18.24,11,11,8,[0,0,0,0,0,1,0,1,0,4,1,1,0,1,2,0],"10.1038/ajg.2016.1"],[28317458,"Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI.","N Engl J Med",2017,"Davies et al.",2,[0],[18.24],18.24,14,11,8,[0,0,0,0,0,0,1,2,2,0,1,2,2,2,0,0],"10.1056/NEJMoa1700445"],[30153967,"Fourth Universal Definition of Myocardial Infarction (2018).","J Am Coll Cardiol",2018,"Thygesen et al.",6,[0],[17.06],18.24,17,15,6,[0,0,0,0,0,0,0,0,1,2,2,5,1,1,3,0],"10.1016/j.jacc.2018.08.1038"],[33119476,"TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes.","J Clin Oncol",2020,"Tung et al.",3,[1],[18.24],18.24,11,11,8,[0,0,0,0,0,0,0,0,0,1,1,1,1,3,3,1],"10.1200/JCO.20.02151"],[21735386,"Exercise-based cardiac rehabilitation for coronary heart disease.","Cochrane Database Syst Rev",2011,"Heran et al.",0,[0],[16.25],18.22,16,14,8,[0,3,3,3,1,2,0,0,1,0,1,0,0,0,0,0],"10.1002/14651858.CD001800.pub2"],[17692741,"Volume-to-creatinine clearance ratio: a pharmacokinetically based risk factor for prediction of early creatinine increase after 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al.",0,[4],[18.17],18.17,13,12,10,[0,0,0,0,0,0,0,0,0,0,0,0,1,2,5,4],"10.1097/HEP.0000000000000004"],[16537877,"Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosis.","Chest",2006,"Lettieri et al.",7,[3,0],[18.13,8.37],18.13,20,10,10,[2,0,2,2,3,1,1,0,0,1,0,1,2,1,1,0],"10.1378/chest.129.3.746"],[18094380,"Infection in solid-organ transplant recipients.","N Engl J Med",2007,"Fishman",6,[2],[7.72],18.13,13,12,9,[4,0,3,0,0,0,1,0,2,0,0,0,0,1,0,1],"10.1056/NEJMra064928"],[19188512,"Ionizing radiation in cardiac imaging: a science advisory from the American Heart Association Committee on Cardiac Imaging of the Council on Clinical Cardiology and Committee on Cardiovascular Imaging and Intervention of the Council on Cardiovascular Radiology and Intervention.","Circulation",2009,"Gerber et al.",7,[13,1],[4.04,0.0],18.13,13,12,8,[3,2,3,2,0,0,1,0,0,0,0,1,0,0,0,0],"10.1161/CIRCULATIONAHA.108.191650"],[22417251,"Prostate-cancer mortality at 11 years of follow-up.","N Engl J Med",2012,"Schröder et al.",2,[1,8,9],[18.13,16.23,16.23],18.13,17,12,8,[0,2,6,4,1,2,0,0,0,0,0,0,1,0,0,0],"10.1056/NEJMoa1113135"],[20929341,"n-3 fatty acids and cardiovascular events after myocardial infarction.","N Engl J Med",2010,"Kromhout et al.",2,[0],[11.65],18.11,16,12,7,[3,1,2,1,1,0,0,2,1,0,0,0,1,0,0,0],"10.1056/NEJMoa1003603"],[22922414,"Third universal definition of myocardial infarction.","Eur Heart J",2012,"Thygesen et al.",4,[0],[16.14],18.11,19,14,7,[0,0,2,3,3,3,3,1,1,0,0,0,0,0,0,0],"10.1093/eurheartj/ehs184"],[23798459,"Effects of intensive blood pressure lowering on the progression of chronic kidney disease: a systematic review and meta-analysis.","CMAJ",2013,"Lv et al.",0,[8,0],[4.23,16.62],18.11,17,12,7,[0,0,0,0,0,1,2,1,2,1,2,0,0,2,2,0],"10.1503/cmaj.121468"],[7565999,"Postprandial versus preprandial blood glucose monitoring in women with gestational diabetes mellitus requiring insulin therapy.","N Engl J Med",1995,"de Veciana et al.",2,[7,9],[18.1,9.48],18.1,12,9,10,[1,0,1,0,1,0,1,1,0,1,1,1,0,1,1,0],"10.1056/NEJM199511093331901"],[10378201,"Development of a valid and reliable malnutrition screening tool for adult acute hospital patients.","Nutrition",1999,"Ferguson et al.",7,[7],[11.84],18.1,10,9,8,[1,1,0,0,1,0,1,0,1,1,0,1,0,1,1,1],"10.1016/s0899-9007(99)00084-2"],[12351469,"High-intensity resistance training improves glycemic control in older patients with type 2 diabetes.","Diabetes Care",2002,"Dunstan et al.",3,[7],[18.1],18.1,14,9,9,[2,1,2,2,1,1,0,0,1,0,0,2,0,1,0,1],"10.2337/diacare.25.10.1729"],[12824205,"Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial.","JAMA",2003,"Chlebowski et al.",2,[1],[11.04],18.1,13,9,8,[1,1,2,1,1,0,3,1,1,0,1,0,0,0,1,0],"10.1001/jama.289.24.3243"],[16757723,"Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial 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warfarin therapy.","Arch Intern Med",2008,"Garcia et al.",5,[0],[14.28],18.1,11,9,8,[1,1,1,1,1,1,0,0,1,0,0,1,0,1,1,0],"10.1001/archinternmed.2007.23"],[19075267,"Hepatitis B virus reactivation in lymphoma patients with prior resolved hepatitis B undergoing anticancer therapy with or without rituximab.","J Clin Oncol",2009,"Yeo et al.",7,[2,4,1],[12.24,9.86,5.78],18.1,13,9,8,[1,1,2,0,0,3,1,0,1,0,1,1,0,1,1,0],"10.1200/JCO.2008.18.0182"],[19153121,"Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial.","Ann Oncol",2009,"Kang et al.",2,[1,4],[18.1,18.1],18.1,12,9,8,[1,1,1,0,1,1,0,1,2,0,0,2,0,0,1,1],"10.1093/annonc/mdn717"],[19386548,"Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): 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transcatheter or surgical aortic-valve replacement.","N Engl J Med",2012,"Kodali et al.",2,[0],[15.56],18.1,22,9,10,[0,1,1,2,1,1,3,1,1,0,1,0,1,0,0,0],"10.1056/NEJMoa1200384"],[24366936,"Cost sharing and adherence to tyrosine kinase inhibitors for patients with chronic myeloid leukemia.","J Clin Oncol",2014,"Dusetzina et al.",7,[1,10],[15.93,1.41],18.08,49,43,3,[0,0,0,0,0,0,2,3,7,8,3,5,5,4,7,3],"10.1200/JCO.2013.52.9123"],[27040723,"Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy.","N Engl J Med",2016,"Velazquez et al.",2,[0],[18.08],18.08,21,13,8,[0,0,0,0,0,0,0,2,1,1,2,4,1,1,1,0],"10.1056/NEJMoa1602001"],[1603139,"The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension.","N Engl J Med",1992,"Rich et al.",3,[0,3],[16.07,14.84],18.05,13,11,8,[2,0,1,0,2,3,0,2,0,1,0,0,0,0,0,1],"10.1056/NEJM199207093270203"],[10690869,"A survey on adrenal incidentaloma in Italy. Study Group on Adrenal Tumors of the Italian Society of Endocrinology.","J Clin Endocrinol Metab",2000,"Mantero et al.",5,[7,1],[18.05,14.06],18.05,12,11,8,[1,0,0,1,0,4,3,1,0,0,0,0,1,0,1,0],"10.1210/jcem.85.2.6372"],[12729424,"Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trial.","Ann Intern Med",2003,"Winston et al.",2,[2],[16.07],18.05,14,11,8,[3,3,2,1,0,2,0,0,1,0,0,0,0,1,0,0],"10.7326/0003-4819-138-9-200305060-00006"],[16740558,"Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials.","BMJ",2006,"Kearney et al.",0,[0],[9.29],18.05,17,11,8,[4,0,1,1,2,0,2,0,1,0,1,0,0,0,0,0],"10.1136/bmj.332.7553.1302"],[17234738,"Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation.","Blood",2007,"Armand et al.",5,[10],[14.44],18.05,12,10,10,[0,0,4,2,0,2,0,0,0,0,2,0,0,2,0,0],"10.1182/blood-2006-10-054924"],[18725221,"Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease.","Gastroenterology",2008,"Van Limbergen et al.",7,[4],[18.05],18.05,13,11,8,[0,1,0,1,1,1,2,3,0,0,0,0,0,0,4,0],"10.1053/j.gastro.2008.06.081"],[19414641,"Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis.","Circulation",2009,"Feng et al.",7,[0,7],[13.55,9.02],18.05,12,11,8,[0,0,0,0,0,1,0,0,0,2,0,1,1,3,1,2],"10.1161/CIRCULATIONAHA.108.785014"],[19571281,"Preoperative staging of lung cancer with combined PET-CT.","N Engl J Med",2009,"Fischer et al.",2,[1,3],[15.44,15.44],18.05,11,11,8,[1,4,2,1,1,0,0,0,1,0,0,0,1,0,0,0],"10.1056/NEJMoa0900043"],[19588325,"Decision aids for people facing health treatment or screening decisions.","Cochrane Database Syst Rev",2009,"O'Connor et al.",0,[1],[6.77],18.05,14,11,8,[2,5,1,1,0,1,0,0,0,1,0,0,0,0,1,0],"10.1002/14651858.CD001431.pub2"],[20026768,"Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis.","Hypertension",2010,"Gupta et al.",0,[0],[15.44],18.05,24,11,10,[0,1,2,0,0,1,0,3,2,0,0,0,0,1,2,0],"10.1161/HYPERTENSIONAHA.109.139816"],[20598634,"Mortality results from the Göteborg randomised population-based prostate-cancer screening trial.","Lancet Oncol",2010,"Hugosson et al.",2,[1,8,9],[18.05,18.05,18.05],18.05,12,11,8,[0,2,3,3,1,1,1,0,0,0,0,0,0,1,0,0],"10.1016/S1470-2045(10)70146-7"],[21910713,"Efficacy and safety of infliximab vs. methotrexate in patients with moderate-to-severe plaque psoriasis: results of an open-label, active-controlled, randomized trial (RESTORE1).","Br J Dermatol",2011,"Barker et al.",2,[14],[18.05],18.05,11,10,10,[0,0,1,0,0,2,1,0,5,1,0,0,0,0,0,0],"10.1111/j.1365-2133.2011.10615.x"],[23780460,"Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children.","JAMA",2013,"Ziegler et al.",5,[7],[18.05],18.05,13,11,8,[0,0,0,3,1,0,1,2,0,0,0,0,0,1,3,2],"10.1001/jama.2013.6285"],[24496537,"Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study.","JAMA",2014,"Marrouche et al.",5,[0],[18.05],18.05,18,11,8,[0,1,0,0,0,2,2,1,0,1,0,0,0,6,1,0],"10.1001/jama.2014.3"],[26210891,"Treatment of venous thromboembolism in patients with cancer: A network meta-analysis comparing efficacy and safety of anticoagulants.","Thromb Res",2015,"Posch et al.",0,[0,1],[16.24,9.3],18.05,12,10,10,[0,0,0,0,0,0,0,2,1,2,5,0,0,0,1,0],"10.1016/j.thromres.2015.07.011"],[28506905,"Eight millimetre covered TIPS does not compromise shunt function but reduces hepatic encephalopathy in preventing variceal rebleeding.","J Hepatol",2017,"Wang et al.",2,[4,5,7],[18.05,1.0,1.0],18.05,11,11,8,[0,0,0,0,0,0,0,1,0,2,3,1,0,1,2,1],"10.1016/j.jhep.2017.05.006"],[29108721,"Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial.","Lancet",2018,"van Brunschot et al.",2,[4],[18.05],18.05,11,10,10,[0,0,0,0,0,0,0,0,0,1,0,3,0,2,2,3],"10.1016/S0140-6736(17)32404-2"],[29222380,"9. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes-2018.","Diabetes Care",2018,"American Diabetes Association",6,[7,0],[15.24,6.2],18.05,10,10,10,[0,0,0,0,0,0,0,3,4,1,1,0,0,0,1,0],"10.2337/dc18-S009"],[29766750,"Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.","N Engl J Med",2018,"Johnston et al.",2,[0,5],[18.05,8.47],18.05,11,10,10,[0,0,0,0,0,0,0,0,0,2,1,1,0,3,0,4],"10.1056/NEJMoa1800410"],[29976470,"Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study.","Lancet",2018,"van der Valk et al.",7,[1,4],[18.05,18.05],18.05,12,10,10,[0,0,0,0,0,0,0,0,0,1,0,1,0,3,4,3],"10.1016/S0140-6736(18)31078-X"],[30067931,"Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults.","N Engl J Med",2018,"Menzies et al.",2,[2],[10.16],18.05,11,10,10,[0,0,0,0,0,0,0,0,0,2,3,0,2,3,1,0],"10.1056/NEJMoa1714283"],[30586750,"Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk.","Circulation",2019,"O'Donoghue et al.",2,[0],[16.24],18.05,11,10,10,[0,0,0,0,0,0,0,0,2,2,2,0,0,2,0,2],"10.1161/CIRCULATIONAHA.118.037184"],[30667501,"Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis.","JAMA",2019,"Zheng et al.",0,[0],[10.85],18.05,10,10,10,[0,0,0,0,0,0,0,0,0,3,1,0,1,4,1,0],"10.1001/jama.2018.20578"],[32215577,"Outcomes of Observation vs Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer: The ORIOLE Phase 2 Randomized Clinical Trial.","JAMA Oncol",2020,"Phillips et al.",2,[1,8,9],[18.05,16.6,16.6],18.05,15,11,8,[0,0,0,0,0,0,0,0,0,2,1,1,1,5,3,1],"10.1001/jamaoncol.2020.0147"],[32756938,"Predictors of preprocedural direct oral anticoagulant levels in patients having an elective surgery or procedure.","Blood Adv",2020,"Shaw et al.",7,[0],[15.24],18.05,11,10,10,[0,0,0,0,0,0,0,0,0,0,1,2,0,4,2,1],"10.1182/bloodadvances.2020002335"],[19038680,"Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms.","J Am Coll Cardiol",2008,"Linde et al.",2,[0],[16.88],18.04,27,14,6,[0,4,3,2,0,1,0,0,1,2,0,1,1,0,0,1],"10.1016/j.jacc.2008.08.027"],[19747792,"Efficacy and safety of immediate angioplasty versus ischemia-guided management after thrombolysis in acute myocardial infarction in areas with very long transfer distances results of the NORDISTEMI (NORwegian study on DIstrict treatment of ST-elevation myocardial infarction).","J Am Coll Cardiol",2010,"Bøhmer et al.",2,[0],[18.03],18.03,22,13,6,[3,2,2,1,2,0,2,1,1,1,0,0,0,0,1,0],"10.1016/j.jacc.2009.08.007"],[1860198,"Stroke Prevention in Atrial Fibrillation Study. Final results.","Circulation",1991,"",2,[0,5],[15.45,7.97],18.01,18,10,8,[2,1,0,1,0,3,0,1,0,1,0,1,0,2,0,0],"10.1161/01.cir.84.2.527"],[1930310,"The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy.","Arthritis Rheum",1991,"Dougados et al.",3,[11,13],[12.65,12.65],18.01,11,10,8,[2,1,0,2,1,1,0,0,1,0,1,1,0,0,0,0],"10.1002/art.1780341003"],[7978443,"Anticoagulants and spinal-epidural anesthesia.","Anesth Analg",1994,"Vandermeulen et al.",6,[0],[10.26],18.01,13,10,8,[0,1,1,3,2,0,0,2,2,1,0,1,0,0,0,0],"10.1213/00000539-199412000-00024"],[9609767,"Clinical events after transjugular intrahepatic portosystemic shunt: correlation with hemodynamic findings.","Gastroenterology",1998,"Casado et al.",5,[4],[18.01],18.01,10,10,8,[0,1,1,0,0,1,0,1,1,0,2,0,0,1,2,0],"10.1016/s0016-5085(98)70436-6"],[9688382,"Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment.","Hum Reprod",1998,"Clark et al.",7,[9],[12.95],18.01,11,10,8,[1,0,2,0,1,1,1,3,0,0,0,0,1,1,0,0],"10.1093/humrep/13.6.1502"],[10202164,"Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer.","N Engl J Med",1999,"Morris et al.",2,[1,9],[18.01,18.01],18.01,12,10,8,[1,3,1,0,0,0,2,0,0,1,0,1,0,1,2,0],"10.1056/NEJM199904153401501"],[10202166,"Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma.","N Engl J Med",1999,"Keys et al.",2,[1,9],[18.01,15.45],18.01,11,10,8,[1,3,1,0,0,0,2,1,0,1,0,1,0,0,1,0],"10.1056/NEJM199904153401503"],[11487535,"Endoscopic and histologic evaluation together with symptom assessment are required to diagnose pouchitis.","Gastroenterology",2001,"Shen et al.",3,[4],[18.01],18.01,11,10,8,[1,0,2,1,2,0,1,2,1,0,0,0,0,0,1,0],"10.1053/gast.2001.26290"],[12003434,"Irritable pouch syndrome: a new category of diagnosis for symptomatic patients with ileal pouch-anal anastomosis.","Am J Gastroenterol",2002,"Shen et al.",7,[4],[18.01],18.01,12,10,9,[2,1,1,0,2,0,0,3,0,0,0,0,1,1,1,0],"10.1111/j.1572-0241.2002.05617.x"],[12107674,"Comparison of three different methods to confirm tracheal tube placement in emergency intubation.","Intensive Care Med",2002,"Grmec",5,[0],[16.6],18.01,12,10,8,[0,0,1,0,3,0,0,0,0,1,1,1,0,1,2,2],"10.1007/s00134-002-1290-x"],[12217281,"Early results of thrombolysis vs anticoagulation in iliofemoral venous thrombosis. A randomised clinical trial.","Eur J Vasc Endovasc Surg",2002,"Elsharawy et al.",2,[0],[18.01],18.01,11,10,8,[1,1,2,1,0,2,0,0,0,1,2,0,1,0,0,0],"10.1053/ejvs.2002.1665"],[12876091,"Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial.","JAMA",2003,"Chiasson et al.",2,[0,7],[9.77,17.16],18.01,13,10,8,[1,1,4,2,0,0,0,0,1,0,1,1,0,0,0,1],"10.1001/jama.290.4.486"],[12970252,"Clinical profiles and outcomes of acute type B aortic dissection in the current era: lessons from the International Registry of Aortic Dissection (IRAD).","Circulation",2003,"Suzuki et al.",7,[0],[18.01],18.01,14,10,8,[0,0,1,1,0,0,1,2,0,0,0,2,2,2,0,1],"10.1161/01.cir.0000087386.07204.09"],[14585937,"Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism.","N Engl J Med",2003,"Büller et al.",2,[0,3],[18.01,7.97],18.01,11,10,8,[2,2,2,1,1,0,0,0,1,1,1,0,0,0,0,0],"10.1056/NEJMoa035451"],[15118975,"Oral Pentasa in the treatment of active Crohn's disease: A meta-analysis of double-blind, placebo-controlled trials.","Clin Gastroenterol Hepatol",2004,"Hanauer et al.",0,[4],[18.01],18.01,12,10,8,[1,1,1,0,0,0,2,2,0,1,0,0,0,3,1,0],"10.1016/s1542-3565(04)00122-3"],[15172900,"Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial.","Ann Intern Med",2004,"Büller et al.",2,[0],[18.01],18.01,11,10,8,[1,3,1,1,0,1,0,0,1,1,2,0,0,0,0,0],"10.7326/0003-4819-140-11-200406010-00007"],[15254054,"Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System.","J Clin Oncol",2004,"Barnholtz-Sloan et al.",7,[1,5],[17.16,13.08],18.01,11,10,8,[1,0,1,1,0,0,1,0,0,0,0,2,0,3,1,1],"10.1200/JCO.2004.12.149"],[15332019,"Most dysplasia in ulcerative colitis is visible at colonoscopy.","Gastrointest Endosc",2004,"Rutter et al.",5,[1,4],[7.47,18.01],18.01,13,10,11,[0,0,3,1,3,0,1,0,1,0,1,0,1,1,0,0],"10.1016/s0016-5107(04)01710-9"],[15483283,"Prosthetic-joint infections.","N Engl J Med",2004,"Zimmerli et al.",6,[2],[14.06],18.01,11,10,8,[1,0,1,0,2,1,1,0,0,0,0,0,0,1,2,1],"10.1056/NEJMra040181"],[15500894,"Single-dose brachytherapy versus metal stent placement for the palliation of dysphagia from oesophageal cancer: multicentre randomised trial.","Lancet",2004,"Homs et al.",2,[4,1,16],[18.01,15.45,1.35],18.01,12,10,8,[2,0,1,0,1,2,0,0,2,0,1,1,0,0,2,0],"10.1016/S0140-6736(04)17272-3"],[16204266,"Atrial fibrillation management: a prospective survey in ESC member countries: the Euro Heart Survey on Atrial Fibrillation.","Eur Heart J",2005,"Nieuwlaat et al.",5,[0],[18.01],18.01,16,10,9,[1,0,2,1,0,3,1,1,0,0,1,0,0,1,0,0],"10.1093/eurheartj/ehi505"],[16405534,"Argon plasma coagulation in the management of symptomatic gastrointestinal vascular lesions: experience in 100 consecutive patients with long-term follow-up.","Am J Gastroenterol",2006,"Kwan et al.",5,[4,0,17],[15.45,1.0,1.0],18.01,10,10,8,[1,0,0,1,0,2,0,0,1,1,2,0,1,0,1,0],"10.1111/j.1572-0241.2006.00370.x"],[16546500,"The importance of preoperative laryngoscopy in patients undergoing thyroidectomy: voice, vocal cord function, and the preoperative detection of invasive thyroid malignancy.","Surgery",2006,"Randolph et al.",5,[7,1,3],[18.01,7.97,4.65],18.01,11,10,8,[1,0,1,1,0,2,0,2,0,0,0,1,1,0,2,0],"10.1016/j.surg.2005.08.009"],[16712713,"Anti-inflammatory and immunosuppressive drugs and reproduction.","Arthritis Res Ther",2006,"Østensen et al.",7,[9],[4.65],18.01,12,10,9,[0,1,0,0,3,1,1,1,0,0,0,0,1,1,1,0],"10.1186/ar1957"],[16932229,"Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome.","Crit Care Med",2006,"Forel et 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al.",7,[1,4],[18.01,18.01],18.01,10,10,8,[0,1,0,1,0,2,1,1,0,0,1,2,0,1,0,0],"10.1016/j.cgh.2008.04.018"],[18718696,"Cachexia: a new definition.","Clin Nutr",2008,"Evans et al.",7,[0],[9.77],18.01,13,10,9,[1,0,0,1,0,2,1,0,0,2,1,1,1,0,0,0],"10.1016/j.clnu.2008.06.013"],[19147615,"Defining minimal disease activity in psoriatic arthritis: a proposed objective target for treatment.","Ann Rheum Dis",2010,"Coates et al.",7,[11,13,14],[18.01,17.16,17.16],18.01,11,10,8,[1,2,0,1,1,1,0,2,1,0,1,0,0,0,0,0],"10.1136/ard.2008.102053"],[19451425,"Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3.","J Clin Oncol",2009,"Van Cutsem et al.",2,[1,4],[18.01,18.01],18.01,13,10,8,[2,1,2,0,0,1,2,0,0,1,0,1,0,2,0,0],"10.1200/JCO.2008.21.6663"],[19720893,"Ten years after mutation testing for Lynch syndrome: cancer incidence and outcome in mutation-positive and mutation-negative family members.","J 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al.",2,[1,10],[18.01,16.6],18.01,10,10,8,[1,1,1,0,2,1,1,0,0,0,0,0,1,2,0,0],"10.1182/blood-2010-03-276246"],[20965785,"Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial.","Lancet Oncol",2010,"Mahon et al.",3,[1,10],[18.01,18.01],18.01,11,10,8,[0,2,0,1,0,1,2,1,0,2,0,1,0,0,1,0],"10.1016/S1470-2045(10)70233-3"],[21708105,"Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease.","Gastroenterology",2011,"Peyrin-Biroulet et al.",5,[1,14,4],[3.1,3.1,13.47],18.01,11,10,8,[0,0,1,1,0,1,2,0,0,1,1,0,0,2,2,0],"10.1053/j.gastro.2011.06.050"],[21968750,"Obstructive sleep apnea: the most common secondary cause of hypertension associated with resistant hypertension.","Hypertension",2011,"Pedrosa et al.",5,[0,3,5],[12.95,2.69,2.69],18.01,15,10,9,[0,0,0,1,0,3,1,2,1,0,0,1,0,1,2,0],"10.1161/HYPERTENSIONAHA.111.179788"],[22051941,"Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP).","Obesity (Silver Spring)",2012,"Allison et al.",2,[7],[15.97],18.01,11,10,9,[0,0,1,0,2,1,1,2,1,0,0,2,0,0,0,1],"10.1038/oby.2011.330"],[22145820,"Risk of first venous thromboembolism in and around pregnancy: a population-based cohort study.","Br J Haematol",2012,"Sultan et al.",5,[9,0,10],[9.02,14.63,5.78],18.01,11,10,8,[0,0,0,1,0,1,0,1,2,2,0,1,0,2,0,1],"10.1111/j.1365-2141.2011.08956.x"],[22261501,"Outcomes of pregnancy in women with autoimmune hepatitis.","J Autoimmun",2012,"Westbrook et al.",6,[4,9],[15.97,4.04],18.01,11,10,8,[0,0,0,0,1,2,1,0,0,1,1,1,2,0,2,0],"10.1016/j.jaut.2011.12.002"],[23473338,"Treatment of anemia with darbepoetin alfa in systolic heart failure.","N Engl J Med",2013,"Swedberg et al.",2,[0,10],[18.01,2.69],18.01,15,10,8,[0,0,2,0,2,1,2,1,0,1,0,1,0,1,0,0],"10.1056/NEJMoa1214865"],[23736733,"Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial.","JAMA",2013,"Ikramuddin et al.",2,[7,0],[15.45,5.78],18.01,14,10,11,[0,0,1,3,1,4,0,1,1,1,0,0,0,0,0,1],"10.1001/jama.2013.5835"],[24155091,"Idiopathic portal hypertension: natural history and long-term outcome.","Hepatology",2014,"Siramolpiwat et al.",7,[4,10],[18.01,0.0],18.01,12,10,8,[0,0,0,0,0,1,1,0,0,2,1,1,0,2,1,2],"10.1002/hep.26904"],[25086187,"An accelerated infliximab induction regimen reduces the need for early colectomy in patients with acute severe ulcerative colitis.","Clin Gastroenterol Hepatol",2015,"Gibson et al.",5,[4],[18.01],18.01,13,10,9,[0,0,0,0,1,0,1,1,0,2,0,0,2,1,4,1],"10.1016/j.cgh.2014.07.041"],[25981135,"Downstaging hepatocellular carcinoma: A systematic review and pooled analysis.","Liver Transpl",2015,"Parikh et al.",1,[4,1],[18.01,15.12],18.01,14,10,10,[0,0,0,0,0,0,0,1,1,0,1,2,1,4,1,1],"10.1002/lt.24169"],[26624850,"On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection.","N Engl J Med",2015,"Molina et al.",2,[2,9,12],[18.01,18.01,18.01],18.01,12,10,8,[0,0,0,0,0,1,3,1,2,0,0,1,1,1,1,0],"10.1056/NEJMoa1506273"],[27153743,"Progestin-only contraception and thromboembolism: A systematic review.","Contraception",2016,"Tepper et al.",1,[0],[10.83],18.01,11,10,8,[0,0,0,0,0,0,0,1,1,0,1,1,1,3,2,1],"10.1016/j.contraception.2016.04.014"],[27846344,"Effect of Evolocumab on Progression of Coronary Disease in Statin-Treated Patients: The GLAGOV Randomized Clinical Trial.","JAMA",2016,"Nicholls et al.",2,[0],[18.01],18.01,10,10,8,[0,0,0,0,0,0,1,0,1,1,1,2,0,2,1,1],"10.1001/jama.2016.16951"],[28898378,"Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women's Health Initiative Randomized Trials.","JAMA",2017,"Manson et al.",2,[1,0],[7.47,6.77],18.01,10,10,8,[0,0,0,0,0,0,1,1,1,1,2,1,0,2,1,0],"10.1001/jama.2017.11217"],[30125216,"Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer.","J Clin Oncol",2018,"Arbour et al.",7,[1,3],[18.01,1.0],18.01,11,10,8,[0,0,0,0,0,0,0,0,2,1,2,1,1,1,1,1],"10.1200/JCO.2018.79.0006"],[12771006,"Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study.","Circulation",2003,"Wang et al.",5,[0],[17.97],17.97,21,11,8,[1,1,2,1,0,3,2,1,0,1,0,0,1,0,0,0],"10.1161/01.CIR.0000072767.89944.6E"],[12957435,"Non-sustained ventricular tachycardia in hypertrophic cardiomyopathy: an independent marker of sudden death risk in young patients.","J Am Coll Cardiol",2003,"Monserrat et al.",7,[0],[17.97],17.97,21,11,7,[1,0,1,1,1,0,0,1,1,1,2,0,0,4,0,0],"10.1016/s0735-1097(03)00827-1"],[17276180,"Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation.","J Am Coll Cardiol",2007,"Gami et al.",5,[0,5,3],[17.97,2.69,0.0],17.97,21,11,8,[1,1,1,1,0,3,2,2,0,1,0,0,0,1,0,0],"10.1016/j.jacc.2006.08.060"],[19423857,"Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists.","Stroke",2009,"Easton et al.",6,[0,5],[15.87,14.62],17.97,15,15,5,[2,1,3,1,2,0,2,0,0,0,0,2,0,1,1,0],"10.1161/STROKEAHA.108.192218"],[21802333,"State of the art on dose prescription, reporting and recording in Intensity-Modulated Radiation Therapy (ICRU report No. 83).","Cancer Radiother",2011,"Grégoire et al.",6,[1],[17.97],17.97,14,11,7,[0,0,1,1,4,2,1,1,0,0,1,1,0,0,2,0],"10.1016/j.canrad.2011.04.003"],[22067390,"Validation study of a quantitative multigene reverse transcriptase-polymerase chain reaction assay for assessment of recurrence risk in patients with stage II colon cancer.","J Clin Oncol",2011,"Gray et al.",5,[1,4],[17.97,17.1],17.97,12,11,7,[0,2,1,0,1,0,1,1,0,1,1,2,0,1,0,0],"10.1200/JCO.2010.32.8732"],[15533851,"Combination of isosorbide dinitrate and hydralazine in blacks with heart failure.","N Engl J Med",2004,"Taylor et al.",2,[0],[15.37],17.91,26,16,5,[1,3,1,0,1,2,2,1,0,2,2,0,0,0,1,1],"10.1056/NEJMoa042934"],[15710776,"Thoracic and abdominal aortic aneurysms.","Circulation",2005,"Isselbacher",6,[0],[17.91],17.91,14,10,7,[1,1,1,0,1,0,0,1,1,0,1,1,2,2,0,1],"10.1161/01.CIR.0000154569.08857.7A"],[20863759,"Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial.","Lancet Oncol",2010,"Krag et al.",2,[1],[17.91],17.91,17,10,8,[1,0,1,2,3,3,1,0,1,0,0,1,0,1,1,1],"10.1016/S1470-2045(10)70207-2"],[31722151,"Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation.","N Engl J Med",2019,"Perez et al.",2,[0],[16.19],17.88,15,13,9,[0,0,0,0,0,0,0,0,0,3,1,0,0,6,3,0],"10.1056/NEJMoa1901183"],[2240918,"Clarifying confusion: the confusion assessment method. A new method for detection of delirium.","Ann Intern Med",1990,"Inouye et al.",5,[5,6],[13.38,13.38],17.85,10,10,9,[0,1,0,0,1,2,0,1,0,0,0,0,0,3,2,0],"10.7326/0003-4819-113-12-941"],[10511366,"Thrombotic risk during pregnancy: a population study.","Obstet Gynecol",1999,"Lindqvist et al.",5,[0,9,10],[15.19,9.17,4.65],17.85,12,10,10,[0,3,1,1,0,0,0,3,0,0,1,0,1,0,0,0],"10.1016/s0029-7844(99)00308-7"],[10622295,"Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group.","Lancet",1999,"Maini et al.",2,[11],[12.16],17.85,10,10,8,[1,4,1,0,2,0,0,1,1,0,0,0,0,0,0,0],"10.1016/s0140-6736(99)05246-0"],[10738049,"Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.","N Engl J Med",2000,"Roy et al.",2,[0],[17.85],17.85,21,10,9,[2,0,0,3,0,3,1,1,0,0,0,0,0,3,0,0],"10.1056/NEJM200003303421302"],[10781266,"Prediction of difficult mask ventilation.","Anesthesiology",2000,"Langeron et al.",5,[3,7],[8.47,9.02],17.85,11,10,9,[0,0,4,1,2,0,0,1,0,1,0,1,0,0,0,0],"10.1097/00000542-200005000-00009"],[11950808,"Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10 year prospective study.","Gut",2002,"Groves et al.",5,[1,4,17],[17.85,17.85,6.84],17.85,10,10,9,[0,0,0,0,3,0,0,0,1,1,0,0,0,2,1,2],"10.1136/gut.50.5.636"],[12799407,"Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS).","JAMA",2003,"Ely et al.",7,[5,6],[9.17,7.47],17.85,10,10,9,[0,0,2,0,4,0,0,1,0,1,0,0,0,1,1,0],"10.1001/jama.289.22.2983"],[14981104,"Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.","J Clin Oncol",2004,"Rebbeck et al.",5,[1],[17.85],17.85,11,10,9,[2,0,0,0,3,2,0,0,0,0,2,1,0,0,1,0],"10.1200/JCO.2004.04.188"],[15007003,"Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study.","Circulation",2004,"Corley et al.",2,[0],[17.85],17.85,13,10,9,[2,2,1,2,0,1,0,0,0,0,0,0,0,2,0,0],"10.1161/01.CIR.0000121736.16643.11"],[15968013,"Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients.","Ann Intern Med",2005,"Gafter-Gvili et al.",0,[10,2],[13.38,9.02],17.85,11,10,9,[5,2,1,0,1,1,0,0,0,0,1,0,0,0,0,0],"10.7326/0003-4819-142-12_part_1-200506210-00008"],[15984971,"The utility of capsule endoscopy small bowel surveillance in patients with polyposis.","Am J Gastroenterol",2005,"Burke et al.",7,[4,1,17],[17.85,10.86,6.84],17.85,10,10,9,[1,0,0,0,3,0,2,0,0,0,1,0,0,1,0,2],"10.1111/j.1572-0241.2005.41506.x"],[16175516,"Randomized clinical trial of postoperative fondaparinux versus perioperative dalteparin for prevention of venous thromboembolism in high-risk abdominal surgery.","Br J Surg",2005,"Agnelli et al.",2,[0],[17.85],17.85,11,10,9,[1,3,3,0,0,0,0,0,0,0,1,1,0,0,0,1],"10.1002/bjs.5154"],[16306522,"Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis.","N Engl J Med",2005,"Groszmann et al.",2,[4],[17.85],17.85,10,10,9,[0,2,2,0,0,0,2,2,0,1,1,0,0,0,0,0],"10.1056/NEJMoa044456"],[16881934,"Prolonged prophylaxis with dalteparin to prevent late thromboembolic complications in patients undergoing major abdominal surgery: a multicenter randomized open-label study.","J Thromb Haemost",2006,"Rasmussen et al.",2,[0],[15.19],17.85,11,10,9,[2,2,4,0,0,0,0,0,1,0,1,0,1,0,0,0],"10.1111/j.1538-7836.2006.02153.x"],[16968831,"Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2.","JAMA",2006,"McGettigan et al.",0,[0],[8.39],17.85,16,10,9,[5,0,2,1,0,0,0,0,1,0,1,0,1,0,0,0],"10.1001/jama.296.13.jrv60011"],[17257990,"Bivalirudin during cardiopulmonary bypass in patients with previous or acute heparin-induced thrombocytopenia and heparin antibodies: results of the CHOOSE-ON trial.","Ann Thorac Surg",2007,"Koster et al.",3,[0,10],[13.27,12.63],17.85,13,10,10,[0,2,2,2,0,0,0,3,1,0,0,0,0,0,0,2],"10.1016/j.athoracsur.2006.09.038"],[17634496,"Impact of primary prophylaxis with granulocyte colony-stimulating factor on febrile neutropenia and mortality in adult cancer patients receiving chemotherapy: a systematic review.","J Clin Oncol",2007,"Kuderer et al.",0,[10,1],[12.63,7.75],17.85,11,10,9,[3,2,1,0,1,2,0,0,1,0,0,0,0,0,0,0],"10.1200/JCO.2006.08.8823"],[17661244,"Determining the treatment strategy for colorectal neoplastic lesions: endoscopic assessment or the non-lifting sign for diagnosing invasion depth?","Endoscopy",2007,"Kobayashi et al.",2,[1,4],[15.95,17.85],17.85,14,10,12,[0,0,1,1,3,0,1,1,0,3,0,0,0,0,0,0],"10.1055/s-2007-966587"],[18093686,"Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy.","J Hepatol",2008,"Abraldes et al.",5,[4],[17.85],17.85,10,10,9,[0,1,1,0,0,0,1,0,0,0,2,2,0,0,3,0],"10.1016/j.jhep.2007.10.008"],[18714778,"Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort.","Sleep",2008,"Young et al.",5,[3,5],[14.06,14.06],17.85,12,10,10,[2,0,1,1,2,1,4,0,0,0,0,0,0,0,0,0],""],[19084016,"Peginterferon alfa-2a plus ribavirin for the treatment of dual chronic infection with hepatitis B and C viruses.","Gastroenterology",2009,"Liu et al.",3,[2,4],[17.85,17.85],17.85,13,10,9,[0,4,0,2,1,3,0,2,0,0,0,0,0,0,1,0],"10.1053/j.gastro.2008.10.049"],[20424251,"Coronary artery calcium score and risk classification for coronary heart disease prediction.","JAMA",2010,"Polonsky et al.",5,[0,7],[15.19,6.2],17.85,13,10,9,[3,0,0,0,0,0,2,0,0,0,2,0,1,1,0,1],"10.1001/jama.2010.461"],[20447957,"Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA.","Ann Rheum Dis",2010,"Nam et al.",1,[11],[15.19],17.85,11,10,9,[0,3,1,3,1,0,1,1,0,0,0,0,0,0,0,0],"10.1136/ard.2009.126573"],[20456751,"Extended prophylaxis with bemiparin for the prevention of venous thromboembolism after abdominal or pelvic surgery for cancer: the CANBESURE randomized study.","J Thromb Haemost",2010,"Kakkar et al.",2,[0,1],[12.55,12.63],17.85,10,10,9,[0,1,5,0,1,0,0,0,1,0,1,0,0,1,0,0],"10.1111/j.1538-7836.2010.03892.x"],[22592743,"Early routine endoscopic retrograde cholangiopancreatography strategy versus early conservative management strategy in acute gallstone pancreatitis.","Cochrane Database Syst Rev",2012,"Tse et al.",0,[4],[17.85],17.85,10,10,9,[0,0,1,0,4,0,2,1,1,0,0,0,0,0,0,1],"10.1002/14651858.CD009779.pub2"],[22910937,"Benefits and harms of statin therapy for persons with chronic kidney disease: a systematic review and meta-analysis.","Ann Intern Med",2012,"Palmer et al.",0,[8,0],[8.39,4.65],17.85,11,10,9,[0,0,2,4,0,0,0,0,0,1,0,1,1,0,0,1],"10.7326/0003-4819-157-4-201208210-00007"],[23860985,"Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial.","JAMA",2013,"Mentzelopoulos et al.",2,[0],[17.85],17.85,17,14,7,[0,0,0,0,8,0,0,1,0,0,0,1,0,1,4,1],"10.1001/jama.2013.7832"],[24480619,"Covered vs. uncovered stents for transjugular intrahepatic portosystemic shunt: a randomized controlled trial.","J Hepatol",2014,"Perarnau et al.",2,[4],[17.85],17.85,10,10,9,[0,0,0,0,0,0,0,0,1,2,2,0,0,1,3,1],"10.1016/j.jhep.2014.01.015"],[24570244,"Prevalence of childhood and adult obesity in the United States, 2011-2012.","JAMA",2014,"Ogden et al.",7,[7],[17.85],17.85,11,10,10,[0,0,0,0,1,3,3,1,2,1,0,0,0,0,0,0],"10.1001/jama.2014.732"],[24725238,"Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.","N Engl J Med",2014,"Afdhal et al.",2,[2,4],[17.85,17.85],17.85,13,10,9,[0,0,0,1,2,4,3,2,0,0,0,1,0,0,0,0],"10.1056/NEJMoa1316366"],[25798575,"Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial.","JAMA Intern Med",2015,"Kutner et al.",2,[0,1,6],[12.16,0.0,0.0],17.85,17,10,9,[0,0,0,0,0,2,0,1,2,2,0,0,0,2,0,2],"10.1001/jamainternmed.2015.0289"],[25956834,"Lifestyle Intervention in Gastroesophageal Reflux Disease.","Clin Gastroenterol Hepatol",2016,"Ness-Jensen et al.",1,[4],[17.85],17.85,13,10,10,[0,0,0,0,0,0,0,1,0,0,0,3,2,3,1,2],"10.1016/j.cgh.2015.04.176"],[26040499,"Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled 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skin-to-skin contact for mothers and their healthy newborn infants.","Cochrane Database Syst Rev",2016,"Moore et al.",0,[17,0],[8.47,4.04],17.85,10,10,9,[0,0,0,0,0,0,0,1,0,3,2,0,1,1,2,0],"10.1002/14651858.CD003519.pub4"],[28274849,"Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.","Gastroenterology",2017,"Weismüller et al.",5,[4],[17.85],17.85,10,10,9,[0,0,0,0,0,0,2,1,1,0,0,2,0,1,3,0],"10.1053/j.gastro.2017.02.038"],[28304219,"Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients.","N Engl J Med",2017,"Reardon et al.",2,[0],[17.85],17.85,14,10,11,[0,0,0,0,0,0,2,0,3,1,2,1,0,1,0,0],"10.1056/NEJMoa1700456"],[28397699,"Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.","Lancet Gastroenterol Hepatol",2017,"Odutayo et al.",0,[4],[12.16],17.85,10,10,9,[0,0,0,0,0,0,0,0,2,2,1,2,1,0,2,0],"10.1016/S2468-1253(17)30054-7"],[28502609,"Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial.","Lancet",2017,"Jørgensen et al.",2,[4],[11.58],17.85,11,10,9,[0,0,0,0,0,0,0,0,2,2,1,0,1,3,2,0],"10.1016/S0140-6736(17)30068-5"],[30073665,"Colloids versus crystalloids for fluid resuscitation in critically ill people.","Cochrane Database Syst Rev",2018,"Lewis et al.",0,[2],[8.47],17.85,10,10,9,[0,0,0,0,0,0,0,0,0,1,1,2,2,3,1,0],"10.1002/14651858.CD000567.pub7"],[30146932,"Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.","N Engl J Med",2018,"Bowman et al.",2,[7,0],[11.58,9.94],17.85,13,10,11,[0,0,0,0,0,0,0,0,2,0,3,1,0,1,1,2],"10.1056/NEJMoa1804989"],[30965069,"Prospective evaluation of a primary care referral pathway for patients with non-alcoholic fatty liver disease.","J Hepatol",2019,"Srivastava et al.",5,[4],[17.85],17.85,12,10,11,[0,0,0,0,0,0,0,0,0,0,1,3,2,1,2,1],"10.1016/j.jhep.2019.03.033"],[31112383,"Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.","N Engl J Med",2019,"Moss et al.",2,[3],[11.58],17.85,12,10,10,[0,0,0,0,0,0,0,0,1,3,0,1,0,1,3,2],"10.1056/NEJMoa1901686"],[31630538,"Cryoballoon or Radiofrequency Ablation for Atrial Fibrillation Assessed by Continuous Monitoring: A Randomized Clinical Trial.","Circulation",2019,"Andrade et al.",2,[0],[17.85],17.85,10,10,9,[0,0,0,0,0,0,0,0,0,1,1,1,0,5,1,1],"10.1161/CIRCULATIONAHA.119.042622"],[31986064,"Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline.","J Clin Oncol",2020,"Konstantinopoulos et al.",0,[1,9,7],[17.85,15.19,14.7],17.85,16,16,7,[0,0,0,0,0,0,0,0,0,1,2,0,1,6,3,3],"10.1200/JCO.19.02960"],[12086760,"Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial.","Lancet",2002,"Chiasson et al.",2,[7],[17.84],17.84,20,12,9,[3,1,2,1,3,1,0,0,0,1,0,1,0,2,0,1],"10.1016/S0140-6736(02)08905-5"],[9468242,"Is ileoscopy with biopsy worthwhile in patients presenting with symptoms of inflammatory bowel disease?","Am J Gastroenterol",1998,"Geboes et al.",5,[4],[17.81],17.81,12,10,8,[1,0,2,2,0,0,0,2,0,0,0,1,1,2,1,0],"10.1111/j.1572-0241.1998.00201.x"],[12003431,"Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy.","Am J Gastroenterol",2002,"Allez et al.",5,[4],[17.81],17.81,11,10,8,[1,0,2,2,0,0,1,1,1,0,0,0,0,1,2,0],"10.1111/j.1572-0241.2002.05614.x"],[12385448,"Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection.","Am J Gastroenterol",2002,"Regev et al.",7,[4,2],[15.77,6.16],17.81,13,10,8,[0,1,1,1,1,1,2,0,0,4,1,0,0,0,0,0],"10.1111/j.1572-0241.2002.06038.x"],[14595302,"Lower frequency of peritoneal carcinomatosis in patients with pancreatic cancer diagnosed by EUS-guided FNA vs. percutaneous FNA.","Gastrointest Endosc",2003,"Micames et al.",5,[1,4,7],[15.78,17.81,13.27],17.81,12,10,9,[1,2,0,1,1,2,2,0,0,0,1,0,0,0,1,0],"10.1016/s0016-5107(03)02009-1"],[14612482,"Efficacy of postoperative epidural analgesia: a meta-analysis.","JAMA",2003,"Block et al.",0,[],[],17.81,14,10,8,[0,1,2,2,2,0,1,0,0,1,1,0,1,0,0,0],"10.1001/jama.290.18.2455"],[17505000,"Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors.","Clin Cancer Res",2007,"Ekeblad et al.",5,[1,7,3],[17.81,9.48,4.65],17.81,11,10,8,[2,3,1,1,1,1,0,1,0,0,0,0,0,0,1,0],"10.1158/1078-0432.CCR-06-2053"],[19617601,"Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a meta-analysis of controlled trials.","Eur Heart J",2009,"Cheng et al.",0,[0],[17.81],17.81,15,10,9,[0,2,0,2,1,1,0,2,0,1,0,0,1,1,0,0],"10.1093/eurheartj/ehp292"],[20124123,"Association of diet, exercise, and smoking modification with risk of early cardiovascular events after acute coronary syndromes.","Circulation",2010,"Chow et al.",7,[0,5],[15.66,0.0],17.81,22,13,8,[1,2,1,1,1,3,0,2,1,1,0,0,0,2,0,0],"10.1161/CIRCULATIONAHA.109.891523"],[20979469,"Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.","N Engl J Med",2010,"Kwak et al.",3,[1,3],[17.81,17.81],17.81,19,10,10,[0,3,4,1,2,0,1,2,0,0,0,0,1,1,0,0],"10.1056/NEJMoa1006448"],[21561346,"Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia.","N Engl J Med",2011,"Boeckxstaens et al.",2,[4],[17.81],17.81,14,10,8,[0,0,1,0,0,1,1,2,0,3,2,0,0,1,1,0],"10.1056/NEJMoa1010502"],[22449319,"Bariatric surgery versus intensive medical therapy in obese patients with diabetes.","N Engl J Med",2012,"Schauer et al.",2,[7],[15.25],17.81,16,10,11,[0,0,2,2,1,2,0,1,1,1,0,0,0,1,0,0],"10.1056/NEJMoa1200225"],[23169523,"Parenteral hydration in patients with advanced cancer: a multicenter, double-blind, placebo-controlled randomized trial.","J Clin Oncol",2013,"Bruera et al.",2,[1,7],[11.84,4.36],17.81,12,10,8,[0,0,0,0,1,3,1,1,0,0,1,0,1,2,0,2],"10.1200/JCO.2012.44.6518"],[25209488,"International standards for fetal growth based on serial ultrasound measurements: the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project.","Lancet",2014,"Papageorghiou et al.",5,[9,17],[17.16,16.6],17.81,11,10,8,[0,0,0,0,0,1,3,1,1,1,0,1,0,2,1,0],"10.1016/S0140-6736(14)61490-2"],[25891304,"Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.","N Engl J Med",2015,"Postow et al.",2,[1,14],[15.77,7.22],17.81,12,10,8,[0,0,0,0,0,2,2,1,2,2,1,1,1,0,0,0],"10.1056/NEJMoa1414428"],[25970050,"Randomized trial of TAS-102 for refractory metastatic colorectal cancer.","N Engl J Med",2015,"Mayer et al.",2,[1,4],[17.81,15.77],17.81,15,10,7,[0,0,0,0,0,0,3,2,1,2,2,0,2,1,0,1],"10.1056/NEJMoa1414325"],[27022822,"Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.","JAMA",2016,"Yeh et al.",2,[0],[17.81],17.81,14,12,7,[0,0,0,0,0,2,1,3,0,2,1,1,0,1,1,0],"10.1001/jama.2016.3775"],[27911262,"Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease.","Gastroenterology",2017,"Park et al.",5,[4],[15.25],17.81,10,10,8,[0,0,0,0,0,0,0,0,1,1,2,1,1,2,1,1],"10.1053/j.gastro.2016.10.026"],[29998301,"Nontraditional Risk Factors in Cardiovascular Disease Risk Assessment: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.","JAMA",2018,"Lin et al.",1,[0,7],[15.77,7.47],17.81,10,10,8,[0,0,0,0,0,0,0,1,1,1,1,0,1,1,3,1],"10.1001/jama.2018.4242"],[2179031,"Clinical, biological, and endoscopic picture of attacks of Crohn's disease. Evolution on prednisolone. Groupe d'Etude Thérapeutique des Affections Inflammatoires Digestives.","Gastroenterology",1990,"Modigliani et al.",3,[4],[17.76],17.76,9,9,9,[1,1,1,3,0,0,1,0,1,0,0,0,0,0,1,0],"10.1016/0016-5085(90)90002-i"],[9060552,"Comparison in low-tumor-burden follicular lymphomas between an initial no-treatment policy, prednimustine, or interferon alfa: a randomized study from the Groupe d'Etude des Lymphomes Folliculaires. Groupe d'Etude des Lymphomes de l'Adulte.","J Clin Oncol",1997,"Brice et al.",2,[1,10],[17.76,17.76],17.76,10,9,9,[2,1,2,2,0,0,0,0,0,1,1,0,0,0,0,1],"10.1200/JCO.1997.15.3.1110"],[10591384,"Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke.","JAMA",1999,"Clark et al.",2,[0,5],[17.76,17.76],17.76,10,9,9,[0,1,4,1,1,0,1,1,1,0,0,0,0,0,0,0],"10.1001/jama.282.21.2019"],[10861320,"Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group.","N Engl J Med",2000,"Vichinsky et al.",5,[10,17,3],[17.76,14.44,4.04],17.76,11,9,9,[0,0,1,2,3,0,0,1,2,1,0,0,0,0,0,1],"10.1056/NEJM200006223422502"],[10905241,"Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score.","Lancet",2000,"Barber et al.",5,[0,5],[17.76,17.76],17.76,10,9,9,[0,1,3,0,0,0,0,0,1,0,1,0,1,1,0,1],"10.1016/s0140-6736(00)02237-6"],[10924966,"A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003.","Int J Radiat Oncol Biol Phys",2000,"Fu et al.",2,[1],[15.17],17.76,9,9,9,[2,0,1,2,0,1,0,1,0,0,0,0,0,1,1,0],"10.1016/s0360-3016(00)00663-5"],[11176842,"Risk of new vertebral fracture in the year following a fracture.","JAMA",2001,"Lindsay et al.",7,[13,7],[17.76,15.78],17.76,11,9,9,[1,0,0,0,1,1,0,0,1,2,0,3,0,0,2,0],"10.1001/jama.285.3.320"],[11177331,"Subcutaneous enoxaparin once or twice daily compared with intravenous unfractionated heparin for treatment of venous thromboembolic disease.","Ann Intern Med",2001,"Merli et al.",2,[0,3],[15.17,2.69],17.76,9,9,9,[2,1,1,0,1,0,0,0,0,0,1,0,0,2,1,0],"10.7326/0003-4819-134-3-200102060-00009"],[11759648,"Mesenteric venous thrombosis.","N Engl J Med",2001,"Kumar et al.",6,[0],[17.76],17.76,9,9,9,[1,2,0,0,0,1,2,1,0,0,0,0,0,1,1,0],"10.1056/NEJMra010076"],[11784873,"Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria.","N Engl J Med",2002,"Borghi et al.",2,[8],[12.63],17.76,9,9,9,[0,0,1,3,0,1,0,0,1,0,0,0,1,1,1,0],"10.1056/NEJMoa010369"],[12059060,"No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer.","Scand J Gastroenterol",2002,"Renkonen-Sinisalo et al.",7,[1,4,7],[17.76,17.76,9.02],17.76,12,9,11,[1,0,2,1,2,1,0,0,0,1,1,0,0,0,0,0],"10.1080/00365520252903134"],[12668987,"Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome.","Hepatology",2003,"Marchesini et al.",7,[4,7],[13.27,1.0],17.76,13,9,11,[0,2,1,0,0,1,1,1,1,0,0,2,0,0,0,0],"10.1053/jhep.2003.50161"],[12814982,"Natural history of venous thromboembolism.","Circulation",2003,"Kearon",6,[0,3],[17.76,4.65],17.76,10,9,9,[0,1,0,1,0,2,1,1,2,0,1,0,0,0,0,0],"10.1161/01.CIR.0000078464.82671.78"],[14999113,"Drug-induced prolongation of the QT interval.","N Engl J Med",2004,"Roden",6,[0,17],[15.17,2.69],17.76,11,9,9,[3,0,1,0,1,1,0,1,0,0,0,0,1,0,1,0],"10.1056/NEJMra032426"],[16424443,"Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study.","Am J Respir Crit Care Med",2006,"Mehra et al.",5,[5,0,3],[10.16,9.02,7.75],17.76,14,9,9,[0,2,2,0,1,1,0,0,1,1,1,0,0,0,0,0],"10.1164/rccm.200509-1442OC"],[16678560,"Functional gastroduodenal disorders.","Gastroenterology",2006,"Tack et al.",6,[6],[1.0],17.76,12,9,10,[1,1,0,0,2,0,1,0,1,0,0,2,0,0,2,0],"10.1053/j.gastro.2005.11.059"],[16989922,"Nodule management protocol of the NELSON randomised lung cancer screening trial.","Lung Cancer",2006,"Xu et al.",2,[3,1],[17.76,17.76],17.76,11,9,10,[0,0,1,0,3,2,1,1,0,0,1,0,0,0,0,1],"10.1016/j.lungcan.2006.08.006"],[17132052,"Projections of global mortality and burden of disease from 2002 to 2030.","PLoS Med",2006,"Mathers et al.",7,[2,9,12],[0.0,0.0,0.0],17.76,9,9,9,[1,2,0,0,1,2,1,0,0,0,1,0,1,0,0,0],"10.1371/journal.pmed.0030442"],[17210844,"Congenital heart disease in the general population: changing prevalence and age distribution.","Circulation",2007,"Marelli et al.",5,[0,17],[17.76,13.27],17.76,11,9,9,[0,0,1,1,2,1,0,0,0,0,0,2,0,0,1,1],"10.1161/CIRCULATIONAHA.106.627224"],[17494927,"Case-control study of human papillomavirus and oropharyngeal cancer.","N Engl J Med",2007,"D'Souza et al.",5,[1,2,9],[13.81,4.65,2.69],17.76,9,9,9,[2,1,2,0,0,1,1,1,0,0,0,0,0,0,1,0],"10.1056/NEJMoa065497"],[17509031,"Systematic review of the risk of enteric infection in patients taking acid suppression.","Am J Gastroenterol",2007,"Leonard et al.",1,[4,2],[15.17,1.0],17.76,10,9,9,[0,0,1,1,0,1,2,0,1,0,0,0,1,0,2,0],"10.1111/j.1572-0241.2007.01275.x"],[17573739,"Acute colonic diverticulitis: a systematic review of diagnostic accuracy.","Colorectal Dis",2007,"Liljegren et al.",1,[4],[17.76],17.76,9,9,9,[1,1,1,1,3,0,0,0,0,1,0,0,0,1,0,0],"10.1111/j.1463-1318.2007.01238.x"],[17577015,"Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial.","J Clin Oncol",2007,"Bartelink et al.",2,[1],[17.76],17.76,12,9,10,[3,2,1,1,1,2,1,0,0,0,0,0,0,0,0,0],"10.1200/JCO.2007.11.4991"],[18398828,"The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome.","Int J Cancer",2008,"Watson et al.",0,[1,4,7],[17.76,17.76,11.84],17.76,14,9,12,[0,2,2,1,1,1,0,0,0,0,0,0,0,2,0,1],"10.1002/ijc.23508"],[18566177,"Effective doses in radiology and diagnostic nuclear medicine: a catalog.","Radiology",2008,"Mettler et al.",6,[],[],17.76,9,9,9,[1,0,3,1,1,1,1,0,0,0,0,1,0,0,0,0],"10.1148/radiol.2481071451"],[18611152,"Diagnostic accuracy of the physical examination and imaging tests for osteomyelitis underlying diabetic foot ulcers: meta-analysis.","Clin Infect Dis",2008,"Dinh et al.",0,[0,14,7],[12.63,12.63,10.16],17.76,13,9,9,[0,1,1,1,0,3,1,0,0,0,0,0,0,1,2,0],"10.1086/590011"],[18838718,"Screening for colorectal cancer: a targeted, updated systematic review for the U.S. Preventive Services Task Force.","Ann Intern Med",2008,"Whitlock et al.",0,[1,4],[17.76,17.76],17.76,11,9,9,[1,2,2,1,1,2,1,0,0,0,0,0,0,0,0,0],"10.7326/0003-4819-149-9-200811040-00245"],[19139027,"Major complications of central neuraxial block: report on the Third National Audit Project of the Royal College of Anaesthetists.","Br J Anaesth",2009,"Cook et al.",7,[5,2,13],[0.0,1.35,1.0],17.76,13,11,6,[0,1,3,0,0,0,1,1,1,1,2,0,0,0,2,1],"10.1093/bja/aen360"],[19183330,"Colonic diverticulitis: a prospective analysis of diagnostic accuracy and clinical decision-making.","Colorectal Dis",2010,"Toorenvliet et al.",5,[4],[17.76],17.76,9,9,9,[0,1,1,1,3,0,0,0,0,1,0,1,0,1,0,0],"10.1111/j.1463-1318.2009.01778.x"],[19523535,"Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease.","Clin Gastroenterol Hepatol",2009,"Shah et al.",7,[4],[13.27],17.76,9,9,9,[0,0,0,0,1,0,0,0,1,1,1,0,3,1,0,1],"10.1016/j.cgh.2009.05.033"],[19610055,"Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed.","Hepatology",2009,"Tripathi et al.",2,[4],[17.76],17.76,9,9,9,[0,2,1,1,0,0,2,0,0,1,1,0,0,1,0,0],"10.1002/hep.23045"],[19625277,"The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years.","Gut",2009,"Feldstein et al.",7,[4],[15.78],17.76,12,9,9,[0,2,1,0,1,1,2,2,0,0,1,0,0,0,0,0],"10.1136/gut.2008.171280"],[19696123,"Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.","Chest",2009,"Kumar et al.",5,[2],[15.78],17.76,12,9,9,[0,1,0,0,1,0,3,0,1,2,1,0,0,0,1,0],"10.1378/chest.09-0087"],[19885906,"Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding.","Inflamm Bowel Dis",2010,"Gisbert",6,[4,9],[11.38,2.69],17.76,9,9,9,[2,0,1,1,1,1,1,2,0,0,0,0,0,0,0,0],"10.1002/ibd.21154"],[20181499,"Clinical management of continuous-flow left ventricular assist devices in advanced heart failure.","J Heart Lung Transplant",2010,"Slaughter et al.",7,[0],[17.76],17.76,9,9,9,[0,2,1,0,1,2,0,1,0,1,0,1,0,0,0,0],"10.1016/j.healun.2010.01.011"],[20683932,"Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B.","Hepatology",2010,"Chang et al.",5,[4,2],[17.76,12.65],17.76,15,11,7,[0,4,1,0,1,2,0,0,1,3,0,1,0,1,1,0],"10.1002/hep.23785"],[21045639,"Prediction of postoperative pulmonary complications in a population-based surgical cohort.","Anesthesiology",2010,"Canet et al.",5,[3],[4.04],17.76,11,9,9,[0,0,1,1,1,0,2,1,0,0,0,1,0,0,0,2],"10.1097/ALN.0b013e3181fc6e0a"],[21146205,"Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study.","Lancet",2010,"Cavo et al.",2,[0,1,10],[17.76,17.76,17.76],17.76,11,9,9,[2,0,3,1,2,0,1,0,0,0,1,1,0,0,0,0],"10.1016/S0140-6736(10)61424-9"],[21173182,"Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2.","Antimicrob Agents Chemother",2011,"Benaboud et al.",7,[2,4],[17.76,10.83],17.76,10,9,9,[0,2,1,0,0,2,1,1,2,0,0,0,0,0,1,0],"10.1128/AAC.00514-10"],[22111719,"Emergency hospitalizations for adverse drug events in older Americans.","N Engl J Med",2011,"Budnitz et al.",7,[6],[1.0],17.76,10,9,9,[0,1,3,0,0,1,0,0,1,0,1,0,1,1,0,0],"10.1056/NEJMsa1103053"],[22273662,"Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity.","Vaccine",2012,"Ott et al.",0,[2,4],[15.17,15.17],17.76,9,9,9,[0,0,1,1,0,2,2,0,1,0,0,1,0,0,0,1],"10.1016/j.vaccine.2011.12.116"],[22345659,"The Oslo definitions for coeliac disease and related terms.","Gut",2013,"Ludvigsson et al.",4,[4,7],[15.17,15.17],17.76,9,9,9,[0,0,2,1,0,0,2,1,0,1,0,0,1,0,1,0],"10.1136/gutjnl-2011-301346"],[22356323,"Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening.","N Engl J Med",2012,"Quintero et al.",2,[1,4],[15.17,15.78],17.76,10,9,9,[0,0,1,0,0,1,1,2,1,0,0,0,2,0,1,0],"10.1056/NEJMoa1108895"],[22414768,"Exercise and non-alcoholic fatty liver disease: a systematic review and meta-analysis.","J Hepatol",2012,"Keating et al.",0,[4],[15.17],17.76,10,9,9,[0,0,2,1,0,1,0,0,0,1,3,0,1,0,0,1],"10.1016/j.jhep.2012.02.023"],[22913681,"Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.","N Engl J Med",2012,"Afdhal et al.",2,[4,10],[15.78,7.22],17.76,12,9,9,[0,0,0,1,0,1,0,0,2,2,2,0,0,1,2,0],"10.1056/NEJMoa1110709"],[22932800,"How I treat anticoagulated patients undergoing an elective procedure or surgery.","Blood",2012,"Spyropoulos et al.",6,[0],[10.16],17.76,10,9,9,[0,0,0,1,0,2,1,0,2,1,1,0,0,0,1,0],"10.1182/blood-2012-06-415943"],[23514285,"Percutaneous closure of patent foramen ovale in cryptogenic embolism.","N Engl J Med",2013,"Meier et al.",2,[0,17],[17.76,6.77],17.76,10,9,10,[0,0,0,1,0,0,1,2,1,2,0,0,1,2,0,0],"10.1056/NEJMoa1211716"],[23558163,"Effect of lower sodium intake on health: systematic review and meta-analyses.","BMJ",2013,"Aburto et al.",0,[0],[13.27],17.76,17,11,8,[0,0,0,0,0,0,1,3,4,0,0,0,1,1,1,1],"10.1136/bmj.f1326"],[23686586,"Primary sclerosing cholangitis, autoimmune hepatitis, and overlap in Utah children: epidemiology and natural history.","Hepatology",2013,"Deneau et al.",5,[4],[17.76],17.76,9,9,9,[0,0,0,0,0,0,1,0,1,1,0,2,0,1,2,1],"10.1002/hep.26454"],[23816960,"Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations.","J Clin Oncol",2013,"Sequist et al.",2,[1,3],[17.76,17.76],17.76,10,9,10,[0,0,0,0,3,1,1,1,2,1,0,0,1,0,0,0],"10.1200/JCO.2012.44.2806"],[24004119,"Results of the two incidence screenings in the National Lung Screening Trial.","N Engl J Med",2013,"Aberle et al.",2,[3,1],[15.78,17.76],17.76,11,9,9,[0,0,0,0,3,1,1,2,0,0,2,0,1,0,1,0],"10.1056/NEJMoa1208962"],[24284028,"Pregnancy outcome following gestational exposure to TNF-alpha-inhibitors: a prospective, comparative, observational study.","Reprod Toxicol",2014,"Diav-Citrin et al.",5,[11,4,14],[6.77,2.69,4.04],17.76,10,9,9,[0,0,0,0,1,1,1,0,0,1,2,0,1,0,2,0],"10.1016/j.reprotox.2013.11.004"],[25476993,"Low-dose total skin electron beam therapy as an effective modality to reduce disease burden in patients with mycosis fungoides: results of a pooled analysis from 3 phase-II clinical trials.","J Am Acad Dermatol",2015,"Hoppe et al.",5,[1,10,14],[17.76,15.17,15.78],17.76,11,9,10,[0,0,0,0,1,0,0,2,1,0,0,1,0,1,4,1],"10.1016/j.jaad.2014.10.014"],[25693014,"Driving pressure and survival in the acute respiratory distress syndrome.","N Engl J Med",2015,"Amato et al.",5,[3],[13.27],17.76,12,9,9,[0,0,0,0,0,0,3,0,2,2,0,1,0,1,1,1],"10.1056/NEJMsa1410639"],[26699168,"Selexipag for the Treatment of Pulmonary Arterial Hypertension.","N Engl J Med",2015,"Sitbon et al.",2,[3,0],[17.76,10.83],17.76,9,9,9,[0,0,0,0,0,1,0,1,1,1,0,0,0,1,2,2],"10.1056/NEJMoa1503184"],[27283860,"Dabrafenib plus trametinib in patients with previously treated BRAF(V600E)-mutant metastatic non-small cell lung cancer: an open-label, multicentre phase 2 trial.","Lancet Oncol",2016,"Planchard et al.",3,[1,3],[17.76,13.27],17.76,13,9,12,[0,0,0,0,0,0,0,2,3,0,1,1,0,1,2,1],"10.1016/S1470-2045(16)30146-2"],[27532827,"Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis.","N Engl J Med",2016,"Vaccarella et al.",7,[1,7],[15.78,15.17],17.76,9,9,9,[0,0,0,0,0,0,1,1,2,1,0,0,1,1,2,0],"10.1056/NEJMp1604412"],[28754778,"Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database.","Gut",2018,"Møller et al.",5,[1,4,7],[17.76,15.17,9.02],17.76,10,9,9,[0,0,0,0,0,0,0,0,3,1,1,1,1,2,0,1],"10.1136/gutjnl-2017-314057"],[29564837,"Prothrombin Complex Concentrate for Major Bleeding on Factor Xa Inhibitors: A Prospective Cohort Study.","Thromb Haemost",2018,"Schulman et al.",5,[0,5,4],[15.78,6.2,0.0],17.76,9,9,9,[0,0,0,0,0,0,0,1,0,1,1,1,1,2,2,0],"10.1055/s-0038-1636541"],[29573941,"Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial.","Lancet Oncol",2018,"Dummer et al.",2,[1,14],[17.76,13.81],17.76,12,9,9,[0,0,0,0,0,0,0,0,2,2,2,1,1,0,3,1],"10.1016/S1470-2045(18)30142-6"],[8172435,"Risk factors for intracranial hemorrhage in outpatients taking warfarin.","Ann Intern Med",1994,"Hylek et al.",5,[0,5],[15.93,6.2],17.74,13,11,10,[2,2,3,0,0,3,0,1,0,0,0,0,0,0,0,0],"10.7326/0003-4819-120-11-199406010-00001"],[14724160,"Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis.","Gut",2004,"Rutter et al.",7,[4],[17.74],17.74,13,11,11,[1,0,3,2,4,0,0,2,0,0,0,0,0,0,0,0],"10.1136/gut.2003.016386"],[21615299,"Mortality after fluid bolus in African children with severe infection.","N Engl J Med",2011,"Maitland et al.",2,[2],[9.17],17.74,16,11,11,[0,0,0,0,3,0,3,0,0,4,0,0,0,1,2,0],"10.1056/NEJMoa1101549"],[21618575,"Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis.","Hepatology",2011,"Hernaez et al.",0,[4],[15.93],17.74,15,11,12,[0,0,0,0,1,0,0,0,0,0,2,3,3,0,0,3],"10.1002/hep.24452"],[25728808,"Randomised clinical trial: faecal microbiota transplantation by colonoscopy vs. vancomycin for the treatment of recurrent Clostridium difficile infection.","Aliment Pharmacol Ther",2015,"Cammarota et al.",2,[2,4],[17.74,1.0],17.74,13,11,9,[0,0,0,0,0,0,0,2,0,2,3,0,0,2,0,2],"10.1111/apt.13144"],[31067138,"Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non-Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study.","J Clin Oncol",2019,"Gomez et al.",2,[1,3],[17.74,13.06],17.74,17,15,8,[0,0,0,0,0,0,0,0,0,1,0,3,3,5,4,0],"10.1200/JCO.19.00201"],[31196453,"Efficacy and Safety of Evolocumab in Chronic Kidney Disease in the FOURIER Trial.","J Am Coll Cardiol",2019,"Charytan et al.",2,[8],[9.17],17.74,14,11,11,[0,0,0,0,0,0,0,0,0,0,1,1,0,2,2,5],"10.1016/j.jacc.2019.03.513"],[34133859,"Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest.","N Engl J Med",2021,"Dankiewicz et al.",2,[0],[15.93],17.74,13,11,10,[0,0,0,0,0,0,0,0,0,0,0,2,2,2,3,2],"10.1056/NEJMoa2100591"],[22090168,"Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study.","Circulation",2012,"Murphy et al.",2,[0],[17.72],17.72,19,11,7,[0,0,1,0,1,1,2,1,2,0,1,0,0,1,2,2],"10.1161/CIRCULATIONAHA.111.075770"],[32109013,"Clinical Characteristics of Coronavirus Disease 2019 in China.","N Engl J Med",2020,"Guan et al.",7,[2,3],[14.1,14.1],17.7,67,63,57,[0,0,0,0,0,0,0,0,0,50,9,2,2,2,0,0],"10.1056/NEJMoa2002032"],[37068504,"Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial.","Lancet",2023,"Shitara et al.",2,[1,4],[17.68,17.68],17.68,12,12,11,[0,0,0,0,0,0,0,0,0,0,0,0,0,4,3,5],"10.1016/S0140-6736(23)00620-7"],[37272534,"Preoperative Treatment of Locally Advanced Rectal Cancer.","N Engl J Med",2023,"Schrag et al.",2,[1,4],[17.68,17.04],17.68,12,12,11,[0,0,0,0,0,0,0,0,0,0,0,0,0,4,6,2],"10.1056/NEJMoa2303269"],[1331787,"A meta-analysis of thoracic radiotherapy for small-cell lung cancer.","N Engl J Med",1992,"Pignon et al.",0,[1,3],[17.66,17.66],17.66,11,9,8,[1,0,2,0,0,0,0,1,0,1,0,2,1,1,1,1],"10.1056/NEJM199212033272302"],[1599520,"Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.","Arthritis Rheum",1992,"Bombardier et al.",7,[11],[15.12],17.66,10,9,8,[1,1,1,1,0,0,1,1,1,0,0,0,0,0,1,1],"10.1002/art.1780350606"],[1638191,"Randomised controlled trial of azathioprine withdrawal in ulcerative colitis.","BMJ",1992,"Hawthorne et al.",2,[4],[17.66],17.66,10,9,9,[0,1,0,0,2,1,1,1,0,1,0,0,1,1,1,0],"10.1136/bmj.305.6844.20"],[7935681,"Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons.","N Engl J Med",1994,"Sawin et al.",7,[0],[5.78],17.66,18,11,7,[1,1,1,2,0,3,1,0,0,2,0,0,0,1,1,0],"10.1056/NEJM199411103311901"],[12131607,"Long-term evolution of disease behavior of Crohn's disease.","Inflamm Bowel Dis",2002,"Cosnes et al.",5,[4],[15.12],17.66,9,9,8,[0,0,1,1,1,0,1,1,0,1,0,1,0,1,1,0],"10.1097/00054725-200207000-00002"],[12662009,"Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness.","Eur Respir J",2003,"Chatwin et al.",5,[3,5],[17.66,6.77],17.66,10,9,8,[0,0,0,1,0,1,2,1,0,1,0,0,1,1,1,1],"10.1183/09031936.03.00048102"],[15213107,"Mortality in relation to smoking: 50 years' observations on male British doctors.","BMJ",2004,"Doll et al.",5,[1],[3.1],17.66,12,9,8,[1,2,1,1,1,1,0,1,0,1,0,0,0,1,0,0],"10.1136/bmj.38142.554479.AE"],[15632335,"Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial.","JAMA",2005,"Dansinger et al.",2,[7,0],[17.1,6.32],17.66,12,11,7,[1,0,2,2,1,2,1,1,0,0,1,1,0,0,0,0],"10.1001/jama.293.1.43"],[15652604,"Global burden of hypertension: analysis of worldwide data.","Lancet",2005,"Kearney et al.",7,[0],[15.12],17.66,9,9,8,[0,1,1,0,1,1,0,1,1,1,1,0,0,1,0,0],"10.1016/S0140-6736(05)17741-1"],[15899030,"Clinical response to discontinuation of anti-TNF therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab.","Arthritis Res Ther",2005,"Baraliakos et al.",3,[11,13],[17.66,17.66],17.66,11,9,8,[2,1,0,1,0,0,1,1,2,0,1,0,1,0,1,0],"10.1186/ar1693"],[16534011,"Acute myocardial infarction in pregnancy: a United States population-based study.","Circulation",2006,"James et al.",7,[0,9],[11.38,13.08],17.66,10,9,8,[1,1,0,0,2,1,0,1,1,0,1,0,0,1,0,1],"10.1161/CIRCULATIONAHA.105.576751"],[16625534,"Strategies for detecting colon cancer and/or dysplasia in patients with inflammatory bowel disease.","Cochrane Database Syst Rev",2006,"Collins et al.",1,[4,1],[17.66,5.78],17.66,11,9,10,[1,0,2,1,2,0,0,0,1,1,1,0,1,1,0,0],"10.1002/14651858.CD000279.pub3"],[16628439,"The accuracy of MRI in diagnosis of suspected deep vein thrombosis: systematic review and meta-analysis.","Eur Radiol",2007,"Sampson et al.",0,[0],[17.66],17.66,12,9,8,[1,3,0,1,0,1,0,1,0,1,1,0,0,1,1,0],"10.1007/s00330-006-0178-5"],[17006923,"Long-term follow-up of patients with NAFLD and elevated liver enzymes.","Hepatology",2006,"Ekstedt et al.",5,[4,0],[17.66,0.0],17.66,15,9,9,[0,2,1,0,2,0,1,1,0,0,1,1,1,1,0,0],"10.1002/hep.21327"],[17950357,"Trends in mortality in bariatric surgery: a systematic review and meta-analysis.","Surgery",2007,"Buchwald et al.",0,[7],[17.66],17.66,11,9,8,[3,1,0,1,1,0,1,1,0,0,1,1,0,1,0,0],"10.1016/j.surg.2007.07.018"],[18602921,"A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitis.","Gastroenterology",2008,"Sands et al.",2,[4],[14.63],17.66,12,9,8,[0,1,3,0,2,0,0,1,1,1,0,0,1,0,1,1],"10.1053/j.gastro.2008.04.023"],[18684186,"Rising prevalence of venous thromboembolism and its impact on mortality among hospitalized inflammatory bowel disease patients.","Am J Gastroenterol",2008,"Nguyen et al.",7,[4,0],[17.66,0.0],17.66,13,9,9,[0,0,2,1,1,1,0,2,1,1,0,0,1,0,3,0],"10.1111/j.1572-0241.2008.02052.x"],[18813036,"Time and cardiac risk of surgery after bare-metal stent percutaneous coronary intervention.","Anesthesiology",2008,"Nuttall et al.",5,[0],[17.66],17.66,21,11,7,[2,2,0,2,2,1,2,1,0,0,0,1,0,1,0,0],"10.1097/ALN.0b013e318186ddf8"],[19230772,"Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study.","Lancet Oncol",2009,"Fenaux et al.",2,[10],[15.12],17.66,16,9,9,[2,1,3,2,1,0,3,0,1,0,2,0,0,0,0,1],"10.1016/S1470-2045(09)70003-8"],[19465232,"Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis.","Lancet",2009,"Bellamy et al.",0,[7,9],[14.28,7.22],17.66,12,9,9,[0,1,1,0,1,1,1,1,1,1,0,2,0,0,0,0],"10.1016/S0140-6736(09)60731-5"],[19470929,"Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy.","J Clin Oncol",2009,"Kopetz et al.",5,[1,4],[15.12,17.66],17.66,9,9,8,[1,1,0,1,1,1,1,0,1,0,0,0,0,1,0,1],"10.1200/JCO.2008.20.5278"],[19720909,"Phase III trial of four cisplatin-containing doublet combinations in stage IVB, recurrent, or persistent cervical carcinoma: a Gynecologic Oncology Group study.","J Clin Oncol",2009,"Monk et al.",2,[1,9],[17.66,17.66],17.66,13,9,8,[1,2,0,0,1,0,1,0,1,0,0,0,2,2,1,2],"10.1200/JCO.2009.21.8909"],[19951276,"Liver transplantation for alcoholic liver disease in Europe: a study from the ELTR (European Liver Transplant Registry).","Am J Transplant",2010,"Burra et al.",7,[4],[15.12],17.66,9,9,8,[0,1,1,1,0,1,0,1,1,1,1,0,0,1,0,0],"10.1111/j.1600-6143.2009.02869.x"],[20410824,"Helicobacter pylori infection and gastric histology in first-degree relatives of gastric cancer patients: a meta-analysis.","Eur J Gastroenterol Hepatol",2010,"Rokkas et al.",0,[4,2,1],[16.81,11.5,9.17],17.66,13,11,8,[0,2,2,1,1,0,1,0,0,0,0,0,0,1,2,2],"10.1097/MEG.0b013e3283398d37"],[21679712,"Durability of radiofrequency ablation in Barrett's esophagus with dysplasia.","Gastroenterology",2011,"Shaheen et al.",2,[1,4],[15.12,17.66],17.66,10,9,8,[0,1,0,1,1,2,0,0,1,1,0,1,0,1,1,0],"10.1053/j.gastro.2011.04.061"],[22161424,"Topical interventions for genital lichen sclerosus.","Cochrane Database Syst Rev",2011,"Chi et al.",0,[9,14,8],[10.15,7.97,3.74],17.66,11,11,7,[0,0,1,1,1,0,0,0,0,1,0,1,1,1,2,2],"10.1002/14651858.CD008240.pub2"],[22529265,"OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer.","J Clin Oncol",2012,"Aghajanian et al.",2,[1,9,7],[17.66,17.66,15.12],17.66,10,9,8,[0,1,2,1,0,0,0,1,1,1,1,0,0,1,0,1],"10.1200/JCO.2012.42.0505"],[22802322,"Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial.","J Clin Oncol",2012,"Sonneveld et al.",2,[0,1,10],[17.66,17.66,17.66],17.66,14,9,8,[0,0,2,2,2,0,2,0,1,1,1,0,0,0,1,2],"10.1200/JCO.2011.39.6820"],[23141049,"Final results of an EORTC-GU cancers group randomized study of maintenance bacillus Calmette-Guérin in intermediate- and high-risk Ta, T1 papillary carcinoma of the urinary bladder: one-third dose versus full dose and 1 year versus 3 years of maintenance.","Eur Urol",2013,"Oddens et al.",2,[1,8],[17.66,17.66],17.66,16,11,8,[0,0,3,0,0,2,0,1,1,1,0,3,0,2,1,2],"10.1016/j.eururo.2012.10.039"],[23177515,"Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial.","Lancet",2013,"Demetri et al.",2,[1,4],[17.66,14.28],17.66,11,9,8,[0,0,0,2,0,1,1,1,1,0,0,1,1,2,1,0],"10.1016/S0140-6736(12)61857-1"],[23352054,"The Transfusion Alternatives Preoperatively in Sickle Cell Disease (TAPS) study: a randomised, controlled, multicentre clinical trial.","Lancet",2013,"Howard et al.",2,[10,17,3],[17.66,14.06,2.0],17.66,11,9,8,[0,0,1,1,2,0,0,1,1,1,2,0,0,0,1,1],"10.1016/S0140-6736(12)61726-7"],[23738544,"Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome.","N Engl J Med",2013,"Legendre et al.",3,[10,8],[14.63,14.63],17.66,11,9,8,[0,0,0,1,1,2,0,0,1,0,1,0,1,1,2,1],"10.1056/NEJMoa1208981"],[23948349,"Long-term results of dose-dense paclitaxel and carboplatin versus conventional paclitaxel and carboplatin for treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (JGOG 3016): a randomised, controlled, open-label trial.","Lancet Oncol",2013,"Katsumata et al.",2,[1,9,7],[17.66,17.66,17.66],17.66,9,9,8,[0,0,0,1,1,1,1,0,1,0,1,1,1,1,0,0],"10.1016/S1470-2045(13)70363-2"],[24352617,"The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003-2012.","JAMA Surg",2014,"Chang et al.",0,[7],[15.97],17.66,14,11,8,[0,0,0,0,0,0,1,1,2,1,1,2,0,2,1,1],"10.1001/jamasurg.2013.3654"],[24583061,"Development of Hong Kong Liver Cancer staging system with treatment stratification for patients with hepatocellular carcinoma.","Gastroenterology",2014,"Yau et al.",5,[1,4],[17.66,17.66],17.66,13,9,10,[0,0,0,0,0,2,1,1,1,1,0,1,1,2,1,0],"10.1053/j.gastro.2014.02.032"],[25482145,"Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma.","N Engl J Med",2015,"Stewart et al.",2,[0,1,10],[17.66,17.66,15.12],17.66,10,9,8,[0,0,0,0,1,1,1,0,2,0,1,1,1,0,1,1],"10.1056/NEJMoa1411321"],[24126876,"A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD).","Eur Heart J",2014,"O'Mahony et al.",5,[0],[17.65],17.65,22,15,5,[0,0,0,2,1,0,3,1,0,2,1,1,1,3,0,2],"10.1093/eurheartj/eht439"],[2473403,"Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction.","N Engl J Med",1989,"Cardiac Arrhythmia Suppression Trial (CA",2,[0],[17.64],17.64,20,14,6,[0,0,5,2,1,2,0,1,0,0,1,1,0,1,0,0],"10.1056/NEJM198908103210629"],[12151467,"Obesity and the risk of heart failure.","N Engl J Med",2002,"Kenchaiah et al.",5,[0,7],[15.6,7.47],17.64,16,12,7,[0,0,1,0,0,4,1,0,1,1,1,0,2,0,1,0],"10.1056/NEJMoa020245"],[18757085,"Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial.","Lancet",2008,"Yusuf et al.",2,[0],[12.89],17.63,26,12,6,[3,1,1,2,3,1,2,1,0,0,0,1,1,1,0,1],"10.1016/S0140-6736(08)61242-8"],[19106084,"Cytochrome p-450 polymorphisms and response to clopidogrel.","N Engl J Med",2009,"Mega et al.",7,[0],[17.63],17.63,24,13,7,[7,2,2,0,0,1,1,0,1,0,0,1,0,0,1,0],"10.1056/NEJMoa0809171"],[34459569,"Effect of Salt Substitution on Cardiovascular Events and Death.","N Engl J Med",2021,"Neal et al.",2,[0,5],[15.94,6.77],17.63,18,13,10,[0,0,0,0,0,0,0,0,0,0,0,0,1,5,4,3],"10.1056/NEJMoa2105675"],[36856617,"Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma.","N Engl J Med",2023,"Patel et al.",2,[1,14],[17.63,15.24],17.63,11,11,10,[0,0,0,0,0,0,0,0,0,0,0,0,2,3,3,3],"10.1056/NEJMoa2211437"],[28329139,"Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT.","Eur Heart J",2017,"Van Gelder et al.",5,[0,5],[17.62,4.65],17.62,18,13,7,[0,0,0,0,0,0,0,2,0,2,2,2,0,5,2,0],"10.1093/eurheartj/ehx042"],[12771112,"Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial.","JAMA",2003,"Shumaker et al.",2,[6,5],[0.0,3.1],17.59,12,8,8,[1,1,1,0,1,0,2,1,1,1,1,1,0,1,0,0],"10.1001/jama.289.20.2651"],[15150204,"Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled 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al.",2,[1],[17.59],17.59,13,8,8,[3,1,1,1,1,1,0,0,1,1,0,0,0,1,1,1],"10.1200/JCO.2008.18.4028"],[20442357,"Previous coronary stent implantation and cardiac events in patients undergoing noncardiac surgery.","Circ Cardiovasc Interv",2010,"Cruden et al.",5,[0],[17.59],17.59,18,10,7,[2,2,1,2,1,1,1,1,0,0,0,1,1,1,0,0],"10.1161/CIRCINTERVENTIONS.109.934703"],[9515998,"Sodium reduction and weight loss in the treatment of hypertension in older persons: a randomized controlled trial of nonpharmacologic interventions in the elderly (TONE). TONE Collaborative Research Group.","JAMA",1998,"Whelton et al.",2,[0],[15.48],17.58,25,14,6,[0,1,1,2,0,3,0,1,4,0,0,0,0,1,1,1],"10.1001/jama.279.11.839"],[3492164,"Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease.","Ann Intern Med",1987,"Anthonisen et al.",2,[3],[17.56],17.56,11,11,9,[2,0,2,0,0,1,5,0,0,0,0,0,0,1,0,0],"10.7326/0003-4819-106-2-196"],[8942774,"Randomised study of screening for colorectal cancer with faecal-occult-blood test.","Lancet",1996,"Kronborg et al.",2,[1,4],[15.76,17.56],17.56,14,11,9,[0,5,3,0,3,0,1,0,0,0,1,0,0,0,0,0],"10.1016/S0140-6736(96)03430-7"],[12020338,"Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus.","JAMA",2002,"Writing Team for the Diabetes Control an",2,[7,0,15],[13.46,4.63,4.63],17.52,12,10,7,[1,2,1,0,0,1,1,1,0,2,1,1,0,1,0,0],"10.1001/jama.287.19.2563"],[14644891,"Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: a 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al.",0,[1,4],[17.52,14.94],17.52,14,12,7,[0,0,4,0,0,0,1,1,1,3,0,0,2,0,2,0],"10.1148/radiol.10100729"],[20850886,"Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study).","J Hepatol",2010,"Degos et al.",3,[4,2],[17.52,12.65],17.52,13,10,7,[1,2,1,2,1,1,1,1,0,1,0,0,0,1,0,0],"10.1016/j.jhep.2010.05.035"],[20921462,"Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer.","J Clin Oncol",2010,"Peeters et al.",2,[1,4],[17.52,17.52],17.52,14,10,7,[1,1,1,2,0,1,2,1,0,1,2,0,0,1,0,0],"10.1200/JCO.2009.27.6055"],[21383294,"Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer.","J Clin Oncol",2011,"Haller et 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al.",5,[0,17],[17.52,3.74],17.52,24,12,7,[0,0,0,3,0,0,0,2,1,0,2,1,3,2,0,0],"10.1001/jama.2011.1286"],[28721881,"Final Report of a Prospective Randomized Trial to Evaluate the Dose-Response Relationship for Postoperative Radiation Therapy and Pathologic Risk Groups in Patients With Head and Neck Cancer.","Int J Radiat Oncol Biol Phys",2017,"Rosenthal et al.",2,[1],[17.51],17.51,15,12,8,[0,0,0,0,0,0,0,0,1,2,1,3,0,3,5,0],"10.1016/j.ijrobp.2017.02.218"],[38856224,"Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis.","N Engl J Med",2024,"Loomba et al.",2,[4],[10.77],17.51,15,13,13,[0,0,0,0,0,0,0,0,0,0,0,0,0,0,6,7],"10.1056/NEJMoa2401943"],[8443907,"A population study of the natural history of Wolff-Parkinson-White syndrome in Olmsted County, Minnesota, 1953-1989.","Circulation",1993,"Munger et al.",5,[0,17],[15.42,1.0],17.46,18,11,7,[1,2,1,0,1,2,0,0,1,1,0,0,0,2,0,0],"10.1161/01.cir.87.3.866"],[9382054,"A double-blind comparison of oral versus rectal 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The thyroid nodule.","N Engl J Med",2004,"Hegedüs",6,[7,1],[17.42,11.58],17.42,10,10,8,[1,0,0,0,1,2,0,1,0,1,1,0,3,0,0,0],"10.1056/NEJMcp031436"],[16279906,"Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease--a randomized, controlled, open-label, multicenter study.","Am J Gastroenterol",2005,"Schröder et al.",2,[4,10,7],[13.47,8.47,2.69],17.42,11,10,9,[1,0,2,1,2,1,0,1,0,0,0,0,0,3,0,0],"10.1111/j.1572-0241.2005.00250.x"],[16382063,"Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease.","N Engl J Med",2005,"Adams et al.",2,[0,5,10],[11.58,5.78,6.2],17.42,11,10,8,[1,3,0,3,0,0,0,0,0,1,0,0,1,1,0,1],"10.1056/NEJMoa050460"],[17443552,"Antiplatelet agents for preventing pre-eclampsia and its complications.","Cochrane Database Syst Rev",2007,"Duley et al.",0,[9],[15.45],17.42,10,10,8,[0,1,0,1,0,2,0,1,0,0,2,0,2,0,1,0],"10.1002/14651858.CD004659.pub2"],[18573856,"Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2.","BMJ",2008,"Hippisley-Cox et al.",7,[0],[9.77],17.42,15,10,8,[0,0,1,3,1,2,1,1,0,1,0,0,0,0,0,0],"10.1136/bmj.39609.449676.25"],[18633639,"Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients.","Langenbecks Arch Surg",2008,"Bergenfelz et al.",5,[7,1],[14.63,4.65],17.42,12,10,8,[0,0,2,0,0,1,0,3,0,1,0,1,0,1,2,0],"10.1007/s00423-008-0366-7"],[18703470,"Effect of PCI on quality of life in patients with stable coronary disease.","N Engl J Med",2008,"Weintraub et al.",2,[0],[17.42],17.42,23,16,6,[3,4,4,3,0,0,0,0,1,0,0,3,2,0,0,0],"10.1056/NEJMoa072771"],[18955670,"Benefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range.","Circulation",2008,"Connolly et al.",2,[0],[17.42],17.42,15,10,8,[1,3,0,0,0,3,1,1,0,1,0,1,0,0,0,0],"10.1161/CIRCULATIONAHA.107.750000"],[19330567,"Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluator-blind, multicentre study.","Scand J Gastroenterol",2009,"Lindgren et al.",2,[4,10],[11.05,10.83],17.42,11,10,9,[0,0,2,1,2,1,0,1,0,0,1,0,0,3,0,0],"10.1080/00365520902839667"],[20097417,"Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.","Lancet",2010,"Bouadma et al.",2,[2],[17.42],17.42,11,10,8,[2,0,0,0,1,2,2,0,1,0,0,0,0,1,1,0],"10.1016/S0140-6736(09)61879-1"],[20581245,"Peutz-Jeghers syndrome: a systematic review and recommendations for management.","Gut",2010,"Beggs et al.",1,[4,1,17],[17.42,14.06,6.2],17.42,10,10,8,[0,0,1,0,3,0,1,1,0,2,1,1,0,0,0,0],"10.1136/gut.2009.198499"],[21045183,"The National Lung Screening Trial: overview and study design.","Radiology",2011,"Aberle et al.",2,[1,3],[17.42,17.42],17.42,11,10,8,[0,2,2,1,1,0,1,3,0,0,0,0,0,0,1,0],"10.1148/radiol.10091808"],[21184054,"Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards.","Osteoporos Int",2011,"Vasikaran et al.",1,[13,7],[14.84,12.95],17.42,12,10,8,[0,2,1,0,0,1,0,0,4,1,1,0,0,2,0,0],"10.1007/s00198-010-1501-1"],[21407190,"Efficacy of 5-aminosalicylates in Crohn's disease: systematic review and meta-analysis.","Am J Gastroenterol",2011,"Ford et al.",0,[4],[17.42],17.42,12,10,8,[0,0,0,1,0,0,2,3,1,1,0,0,0,3,1,0],"10.1038/ajg.2011.71"],[21424201,"The effectiveness and safety of endoscopic submucosal dissection compared with endoscopic mucosal resection for early gastric cancer: a systematic review and metaanalysis.","Surg Endosc",2011,"Park et al.",0,[1,4],[17.42,17.42],17.42,10,10,8,[0,0,0,0,2,1,0,0,2,1,1,0,0,0,1,2],"10.1007/s00464-011-1627-z"],[21751907,"The coagulopathy of chronic liver disease.","N Engl J Med",2011,"Tripodi et al.",6,[4,0,10],[17.42,8.47,4.65],17.42,11,10,8,[0,0,0,0,0,1,1,0,0,2,2,0,0,2,1,1],"10.1056/NEJMra1011170"],[21791495,"Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials.","BMJ",2011,"Boussageon et al.",0,[7,0],[12.16,9.77],17.42,11,10,9,[0,0,2,1,1,0,0,2,2,0,1,0,0,1,0,0],"10.1136/bmj.d4169"],[22072065,"Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score.","Cancer",2012,"Extermann et al.",5,[1],[17.42],17.42,10,10,8,[0,0,0,2,0,0,0,2,1,1,1,0,1,0,2,0],"10.1002/cncr.26646"],[22289875,"Efficacy and safety of anticoagulation on patients with cirrhosis and portal vein thrombosis.","Clin Gastroenterol Hepatol",2012,"Delgado et al.",7,[4,0],[17.42,10.26],17.42,11,10,8,[0,0,0,0,0,1,2,0,1,1,3,0,0,0,2,1],"10.1016/j.cgh.2012.01.012"],[22434203,"A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis.","Osteoporos Int",2012,"Lekamwasam et al.",1,[7,13],[17.42,14.84],17.42,11,10,8,[0,1,2,3,1,0,0,0,2,0,0,0,0,1,1,0],"10.1007/s00198-012-1958-1"],[22513925,"Total versus subtotal hysterectomy for benign gynaecological conditions.","Cochrane Database Syst Rev",2012,"Lethaby et al.",0,[9],[14.63],17.42,11,10,8,[0,0,0,1,2,1,2,0,1,0,2,0,0,0,1,0],"10.1002/14651858.CD004993.pub3"],[22610003,"The prevalence and diagnostic utility of endoscopic features of eosinophilic esophagitis: a meta-analysis.","Clin Gastroenterol Hepatol",2012,"Kim et al.",0,[4,10,12],[17.42,11.58,11.58],17.42,10,10,8,[0,0,1,0,0,0,1,1,0,1,0,0,0,2,3,1],"10.1016/j.cgh.2012.04.019"],[22772328,"Efficacy and safety of 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al.",2,[0,5],[17.42,6.77],17.42,13,10,8,[0,0,0,2,1,2,1,3,1,1,0,0,0,0,0,0],"10.1016/j.jacc.2013.02.025"],[23547075,"Sequential phase I and II trials of stereotactic body radiotherapy for locally advanced hepatocellular carcinoma.","J Clin Oncol",2013,"Bujold et al.",3,[1,4],[17.42,16.6],17.42,13,10,9,[0,0,0,0,1,2,2,0,0,0,2,3,1,1,0,0],"10.1200/JCO.2012.44.1659"],[23623721,"Integration of 3D digital mammography with tomosynthesis for population breast-cancer screening (STORM): a prospective comparison study.","Lancet Oncol",2013,"Ciatto et al.",5,[1],[17.42],17.42,10,10,8,[0,0,0,0,0,1,3,0,0,1,1,0,0,1,1,2],"10.1016/S1470-2045(13)70134-7"],[23922146,"Endovascular repair of type B aortic dissection: long-term results of the randomized investigation of stent grafts in aortic dissection trial.","Circ Cardiovasc Interv",2013,"Nienaber et al.",2,[0],[17.42],17.42,14,10,9,[0,0,0,2,0,0,1,0,0,1,0,2,3,2,0,1],"10.1161/CIRCINTERVENTIONS.113.000463"],[23979084,"The transfer of drugs and therapeutics into human breast milk: an update on selected topics.","Pediatrics",2013,"Sachs et al.",7,[9],[5.29],17.42,13,13,8,[0,0,0,2,0,3,3,2,0,0,3,0,0,0,0,0],"10.1542/peds.2013-1985"],[24101040,"Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.","J Clin Oncol",2013,"Gilbert et al.",2,[1,5],[17.42,15.45],17.42,12,10,8,[0,0,0,2,0,1,2,1,0,0,0,2,0,0,2,1],"10.1200/JCO.2013.49.6968"],[25512465,"Long-term follow-up of a large active surveillance cohort of patients with prostate cancer.","J Clin Oncol",2015,"Klotz et al.",7,[1,8,9],[17.42,17.42,17.42],17.42,11,10,8,[0,0,0,0,0,2,1,2,2,1,0,2,0,1,0,0],"10.1200/JCO.2014.55.1192"],[25724455,"Trough concentrations of infliximab guide dosing for patients with inflammatory bowel disease.","Gastroenterology",2015,"Vande Casteele et al.",2,[4],[17.42],17.42,12,10,8,[0,0,0,0,0,0,2,0,1,2,0,0,1,4,1,1],"10.1053/j.gastro.2015.02.031"],[25765769,"Sudden cardiac death in the young: the molecular autopsy and a practical 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sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure.","Eur J Cancer",2009,"George et al.",2,[1,4],[17.21,17.21],17.21,11,8,8,[0,1,1,2,0,0,1,1,1,0,0,1,1,1,1,0],"10.1016/j.ejca.2009.02.011"],[22913680,"Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects.","N Engl J Med",2012,"Carlsson et al.",3,[7],[14.69],17.21,15,10,10,[0,0,2,1,1,1,0,1,2,1,0,1,1,0,0,1],"10.1056/NEJMoa1112082"],[33755728,"Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial.","JAMA",2021,"Rubino et al.",2,[7],[13.25],17.18,16,12,9,[0,0,0,0,0,0,0,0,0,0,0,1,0,2,3,6],"10.1001/jama.2021.3224"],[34454674,"Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study.","Lancet",2021,"Sun et 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Systolic Hypertension in Europe Trial Investigators.","JAMA",1999,"Staessen et al.",2,[0],[17.16],17.16,11,9,8,[0,2,1,0,1,0,0,0,1,1,0,0,0,1,1,1],"10.1001/jama.282.6.539"],[10573044,"Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. 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adults with supratentorial low-grade glioma: initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group study.","J Clin Oncol",2002,"Shaw et al.",2,[1,5],[17.16,17.16],17.16,11,9,8,[0,0,1,1,1,1,0,1,0,0,0,2,0,1,2,0],"10.1200/JCO.2002.09.126"],[12079904,"Safety and efficacy of vaccination against hepatitis B in patients with rheumatoid arthritis.","Ann Rheum Dis",2002,"Elkayam et al.",3,[11,2,4],[17.16,5.29,0.0],17.16,9,9,8,[2,0,1,1,1,1,0,0,1,0,0,0,0,1,0,1],"10.1136/ard.61.7.623"],[12766131,"Hypoglycemia in diabetes.","Diabetes Care",2003,"Cryer et al.",6,[7],[13.08],17.16,12,9,8,[1,2,4,1,1,0,0,1,0,0,0,1,1,0,0,0],"10.2337/diacare.26.6.1902"],[12788870,"Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results.","J Clin Endocrinol Metab",2003,"Eisenhofer et al.",7,[1,7],[14.63,14.63],17.16,9,9,8,[1,0,0,2,0,1,1,1,1,0,1,0,0,0,0,1],"10.1210/jc.2002-030005"],[14084741,"THE COURSE AND PROGNOSIS OF ULCERATIVE COLITIS.","Gut",1963,"EDWARDS et al.",7,[4,1],[17.16,1.35],17.16,11,9,8,[3,0,0,0,1,0,1,2,1,0,0,0,1,1,1,0],"10.1136/gut.4.4.299"],[15014181,"A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer.","N Engl J Med",2004,"Coombes et al.",2,[1],[15.12],17.16,11,9,8,[2,2,1,1,2,0,0,0,0,0,1,0,0,1,0,1],"10.1056/NEJMoa040331"],[15125788,"A meta-analysis of prior corticosteroid use and fracture risk.","J Bone Miner Res",2004,"Kanis et al.",0,[13],[17.16],17.16,12,9,8,[1,0,1,1,0,1,0,0,2,0,0,1,0,2,3,0],"10.1359/JBMR.040134"],[15169803,"Phase III trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma: a Gynecologic Oncology Group Study.","J Clin Oncol",2004,"Fleming et al.",3,[1,9],[17.16,14.63],17.16,10,9,8,[1,1,0,2,0,0,2,1,0,1,0,0,1,0,1,0],"10.1200/JCO.2004.07.184"],[15183621,"Cervical cerclage for prevention of preterm delivery in women with 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al.",5,[0],[17.16],17.16,10,9,8,[1,0,2,2,0,1,1,0,0,0,1,1,1,0,0,0],"10.1016/S0140-6736(07)60314-6"],[17481518,"Effect of infliximab on short-term complications in patients undergoing operation for chronic ulcerative colitis.","J Am Coll Surg",2007,"Selvasekar et al.",5,[4],[14.63],17.16,10,9,8,[3,1,0,1,1,0,1,0,0,0,0,0,1,1,1,0],"10.1016/j.jamcollsurg.2006.12.044"],[17519271,"Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis.","Rheumatology (Oxford)",2007,"Metzler et al.",2,[0,11,14],[14.63,14.63,13.27],17.16,10,9,8,[1,1,0,0,1,1,0,0,0,0,1,0,1,1,2,0],"10.1093/rheumatology/kem029"],[17544877,"Comparison of the interobserver reproducibility with different histologic criteria used in celiac disease.","Clin Gastroenterol Hepatol",2007,"Corazza et al.",7,[4,7],[17.16,14.63],17.16,9,9,8,[0,1,1,1,1,0,0,1,1,0,0,1,0,0,2,0],"10.1016/j.cgh.2007.03.019"],[17560680,"Noradrenalin vs terlipressin in patients with hepatorenal 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al.",7,[1,9,10],[14.63,8.47,5.08],17.16,10,9,8,[0,2,0,1,0,0,1,2,0,0,1,1,0,1,0,1],"10.1182/blood-2007-05-090225"],[17971582,"Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients.","J Clin Oncol",2007,"Kam et al.",2,[1,16],[17.16,7.22],17.16,10,9,8,[1,1,1,1,0,3,0,0,0,0,1,1,0,0,1,0],"10.1200/JCO.2007.11.5501"],[18027884,"Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis.","Hepatology",2008,"Kulik et al.",3,[1,4,0],[17.16,17.16,0.0],17.16,13,9,8,[1,2,2,0,0,1,2,0,0,0,1,0,1,1,0,0],"10.1002/hep.21980"],[18043101,"Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the mid/distal esophagus: five-year survival of a randomized clinical trial.","Ann Surg",2007,"Omloo et al.",2,[1,4],[17.16,17.16],17.16,9,9,7,[1,0,1,1,1,0,0,0,2,0,1,0,0,1,1,0],"10.1097/SLA.0b013e31815c4037"],[18305265,"Vasopressin versus norepinephrine infusion in patients with septic shock.","N Engl J Med",2008,"Russell et al.",2,[2],[10.26],17.16,13,9,8,[1,0,2,1,0,1,1,0,0,2,0,0,0,2,1,0],"10.1056/NEJMoa067373"],[18376169,"Prehospital tourniquet use in Operation Iraqi Freedom: effect on hemorrhage control and outcomes.","J Trauma",2008,"Beekley et al.",5,[13],[7.97],17.16,12,9,9,[1,1,0,1,2,0,1,0,0,0,0,1,1,0,1,0],"10.1097/TA.0b013e318160937e"],[18433467,"Autoimmune hepatitis overlap syndromes: an evaluation of treatment response, long-term outcome and survival.","Aliment Pharmacol Ther",2008,"Al-Chalabi et al.",7,[4],[17.16],17.16,10,9,8,[1,0,0,0,2,0,0,1,1,1,0,0,1,0,2,1],"10.1111/j.1365-2036.2008.03722.x"],[18458170,"Results of the Predictors of Response to CRT (PROSPECT) trial.","Circulation",2008,"Chung et al.",3,[0],[17.16],17.16,18,11,7,[0,4,1,2,0,1,0,0,1,1,1,0,1,0,0,0],"10.1161/CIRCULATIONAHA.107.743120"],[18688876,"Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis.","Hepatology",2008,"Yao et al.",5,[1,4],[17.16,17.16],17.16,14,9,10,[0,2,1,0,1,1,1,0,1,0,0,2,0,2,0,0],"10.1002/hep.22412"],[18716113,"Prevalence of unsuspected pancreatic cysts on MDCT.","AJR Am J Roentgenol",2008,"Laffan et al.",5,[1,4],[17.16,17.16],17.16,9,9,8,[0,1,1,1,0,1,1,2,0,1,0,0,0,0,0,1],"10.2214/AJR.07.3340"],[18774746,"Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial.","Lancet Neurol",2008,"Eckstein et al.",2,[0,5],[17.16,14.63],17.16,17,9,8,[3,1,1,2,0,0,1,0,0,0,0,1,1,1,0,0],"10.1016/S1474-4422(08)70196-0"],[19137428,"EUS-guided celiac plexus neurolysis for pain due to chronic pancreatitis or pancreatic cancer pain: a meta-analysis and systematic review.","Dig Dis Sci",2009,"Puli et al.",0,[4,1,7],[15.12,4.65,1.0],17.16,11,9,8,[0,2,1,0,1,1,0,3,0,0,0,1,0,1,1,0],"10.1007/s10620-008-0651-x"],[19228619,"IDH1 and IDH2 mutations in gliomas.","N Engl J Med",2009,"Yan et al.",7,[1,5],[17.16,12.65],17.16,10,9,8,[1,0,0,2,1,0,1,0,1,0,1,2,0,0,0,1],"10.1056/NEJMoa0808710"],[19248087,"The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort.","Arthritis Rheum",2009,"Rudwaleit et al.",5,[11,13],[17.16,17.16],17.16,14,9,8,[1,2,1,1,0,0,3,1,1,0,0,0,1,0,0,0],"10.1002/art.24483"],[19340881,"Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease.","Inflamm Bowel Dis",2009,"Schnitzler et al.",5,[4],[17.16],17.16,9,9,8,[1,0,1,2,1,0,1,0,1,1,0,0,0,1,0,0],"10.1002/ibd.20927"],[19417195,"Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention.","JAMA",2009,"Mehta et al.",7,[0],[17.16],17.16,16,11,7,[0,1,1,2,0,0,1,2,1,0,0,0,0,1,3,0],"10.1001/jama.2009.600"],[19602972,"Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literature.","Crit Care Med",2009,"Marik et al.",0,[],[],17.16,11,9,8,[0,1,2,1,1,1,1,0,0,0,0,0,0,2,1,0],"10.1097/CCM.0b013e3181a590da"],[19616440,"Postoperative blood loss in patients undergoing coronary artery bypass surgery after preoperative treatment with clopidogrel. A prospective randomised controlled study.","Eur J Cardiothorac Surg",2009,"Firanescu et al.",2,[0],[14.63],17.16,15,11,7,[2,2,1,2,1,0,0,0,2,0,0,1,0,1,0,0],"10.1016/j.ejcts.2009.05.032"],[19783324,"Does end tidal CO2 monitoring during emergency department procedural sedation and analgesia with propofol decrease the incidence of hypoxic events? A randomized, controlled trial.","Ann Emerg Med",2010,"Deitch et al.",2,[3],[10.83],17.16,9,9,8,[1,0,1,1,1,0,0,2,0,0,0,1,0,1,1,0],"10.1016/j.annemergmed.2009.07.030"],[19822628,"Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome.","JAMA",2009,"Davies et al.",7,[3,2],[14.63,3.74],17.16,10,9,10,[1,1,0,2,0,0,1,0,1,1,1,0,1,0,0,0],"10.1001/jama.2009.1535"],[19854715,"Drug-specific risk of tuberculosis in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register (BSRBR).","Ann Rheum Dis",2010,"Dixon et al.",7,[11,2,3],[12.16,4.65,0.0],17.16,9,9,8,[1,2,1,0,0,1,1,1,1,0,0,0,0,0,1,0],"10.1136/ard.2009.118935"],[20363409,"Safety and efficacy of endoscopic spray cryotherapy for Barrett's esophagus with high-grade dysplasia.","Gastrointest Endosc",2010,"Shaheen et al.",5,[1,4],[15.12,17.16],17.16,10,9,8,[1,2,0,1,2,1,0,0,0,1,0,1,1,0,0,0],"10.1016/j.gie.2010.01.018"],[20517305,"Treatment of relapsing mild-to-moderate ulcerative colitis with the probiotic VSL#3 as adjunctive to a standard pharmaceutical treatment: a double-blind, randomized, placebo-controlled study.","Am J Gastroenterol",2010,"Tursi et al.",2,[4],[17.16],17.16,11,9,8,[0,2,1,0,1,0,0,1,1,2,0,0,2,0,1,0],"10.1038/ajg.2010.218"],[20525678,"Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study.","BMJ",2010,"Renoux et al.",5,[0,5],[12.65,2.69],17.16,11,9,8,[0,2,0,0,1,0,2,1,0,0,2,1,0,1,1,0],"10.1136/bmj.c2519"],[20637202,"A sustained virologic response is durable in patients with chronic hepatitis C treated with peginterferon alfa-2a and ribavirin.","Gastroenterology",2010,"Swain et al.",2,[2,4],[14.63,14.63],17.16,13,9,8,[0,1,0,1,2,2,3,1,0,1,0,0,0,0,1,0],"10.1053/j.gastro.2010.07.009"],[20801122,"Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation.","Gastroenterology",2010,"Johnston et al.",2,[4],[17.16],17.16,9,9,8,[0,0,1,0,1,0,1,1,0,0,1,1,1,0,2,0],"10.1053/j.gastro.2010.08.041"],[20818888,"Icatibant, a new bradykinin-receptor antagonist, in hereditary angioedema.","N Engl J Med",2010,"Cicardi et al.",2,[0,12,14],[17.16,17.16,17.16],17.16,11,9,8,[1,2,2,1,1,0,0,2,0,0,0,1,0,0,0,1],"10.1056/NEJMoa0906393"],[20920599,"Esophageal eosinophilic infiltration responds to proton pump inhibition in most adults.","Clin Gastroenterol Hepatol",2011,"Molina-Infante et al.",5,[4,10,12],[17.16,14.63,14.63],17.16,9,9,8,[0,0,1,1,0,1,0,1,1,1,0,0,0,2,1,0],"10.1016/j.cgh.2010.09.019"],[21034228,"Estimating risk of recurrence in differentiated thyroid cancer after total thyroidectomy and radioactive iodine remnant ablation: using response to therapy variables to modify the initial risk estimates predicted by the new American Thyroid Association staging system.","Thyroid",2010,"Tuttle et al.",5,[7,1],[17.16,15.12],17.16,11,9,8,[0,1,0,2,1,1,0,0,2,0,0,0,0,1,2,1],"10.1089/thy.2010.0178"],[21068095,"Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores.","Ann Rheum Dis",2011,"Machado et al.",7,[11,13],[17.16,17.16],17.16,12,9,8,[1,2,0,2,1,0,2,1,1,0,0,0,2,0,0,0],"10.1136/ard.2010.138594"],[21136562,"Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis.","Br J Surg",2011,"van Baal et al.",1,[4],[17.16],17.16,10,9,8,[0,1,2,0,1,1,1,0,0,0,0,0,0,2,1,1],"10.1002/bjs.7304"],[21242484,"Safety of percutaneous left atrial appendage closure: results from the Watchman Left Atrial Appendage System for Embolic Protection in Patients with AF (PROTECT AF) clinical trial and the Continued Access Registry.","Circulation",2011,"Reddy et al.",3,[0],[17.16],17.16,11,9,8,[0,1,1,1,1,2,1,1,0,0,0,1,0,0,0,0],"10.1161/CIRCULATIONAHA.110.976449"],[21699833,"Temporal relationship of atrial tachyarrhythmias, cerebrovascular events, and systemic emboli based on stored device data: a subgroup analysis of TRENDS.","Heart Rhythm",2011,"Daoud et al.",5,[0,5],[17.16,6.77],17.16,16,9,9,[0,1,0,1,0,3,1,3,0,1,0,0,0,1,1,0],"10.1016/j.hrthm.2011.04.022"],[21725957,"Randomized clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy and surgical stripping for great saphenous varicose veins.","Br J Surg",2011,"Rasmussen et al.",2,[0],[17.16],17.16,14,11,8,[0,0,0,2,2,1,0,0,0,3,2,1,1,0,0,1],"10.1002/bjs.7555"],[21791513,"Non-cardiac surgery in patients with coronary stents: the RECO study.","Heart",2011,"Albaladejo et al.",5,[0],[17.16],17.16,13,9,9,[0,1,0,2,0,0,1,1,1,0,0,1,1,1,0,0],"10.1136/hrt.2011.224519"],[22115374,"Detection of infliximab in breast milk of nursing mothers with inflammatory bowel disease.","J Crohns Colitis",2011,"Ben-Horin et al.",7,[4],[4.65],17.16,10,9,8,[0,0,1,0,0,1,1,0,1,0,1,1,2,0,0,1],"10.1016/j.crohns.2011.05.006"],[22365425,"Long-term follow-up of biopsy-proven viral myocarditis: predictors of mortality and incomplete recovery.","J Am Coll Cardiol",2012,"Grün et al.",5,[0,2],[17.16,1.0],17.16,9,9,8,[0,0,2,0,0,0,0,1,1,1,1,1,1,0,1,0],"10.1016/j.jacc.2012.01.007"],[22551105,"Warfarin and aspirin in patients with heart failure and sinus rhythm.","N Engl J Med",2012,"Homma et al.",2,[0],[17.16],17.16,15,11,7,[0,1,2,2,0,1,2,1,0,0,1,0,0,2,0,0],"10.1056/NEJMoa1202299"],[22613903,"Narrow band imaging for detection of dysplasia in colitis: a randomized controlled trial.","Am J Gastroenterol",2012,"Ignjatovic et al.",2,[4],[17.16],17.16,11,9,10,[0,0,1,1,2,0,0,1,2,0,1,0,1,1,0,0],"10.1038/ajg.2012.67"],[22830463,"Sirolimus and secondary skin-cancer prevention in kidney transplantation.","N Engl J Med",2012,"Euvrard et al.",2,[1,14],[15.12,13.08],17.16,11,9,8,[0,0,0,1,2,1,0,2,0,2,0,1,1,0,0,1],"10.1056/NEJMoa1204166"],[22963114,"Venous thromboembolism risk in relation to use of different types of postmenopausal hormone therapy in a large prospective study.","J Thromb Haemost",2012,"Sweetland et al.",5,[0],[10.26],17.16,11,9,7,[0,0,0,1,1,0,1,0,1,3,1,1,0,1,0,0],"10.1111/j.1538-7836.2012.04919.x"],[23291385,"The role of methotrexate co-medication in TNF-inhibitor treatment in patients with psoriatic arthritis: results from 440 patients included in the NOR-DMARD study.","Ann Rheum Dis",2014,"Fagerli et al.",5,[14,11,13],[14.63,12.65,10.26],17.16,10,9,8,[0,0,0,1,1,2,1,1,1,1,0,0,0,1,0,0],"10.1136/annrheumdis-2012-202347"],[23524219,"Triple therapy with aspirin, prasugrel, and vitamin K antagonists in patients with drug-eluting stent implantation and an indication for oral anticoagulation.","J Am Coll Cardiol",2013,"Sarafoff et 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al.",0,[0],[12.65],17.16,13,9,8,[0,0,0,0,1,2,0,1,0,1,1,0,1,2,0,1],"10.1136/bmj.f6879"],[24703918,"Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy: a systematic review.","J Am Coll Cardiol",2014,"Thavendiranathan et al.",1,[0,1],[14.63,7.97],17.16,9,9,8,[0,0,0,0,0,2,1,0,0,1,1,1,1,0,1,1],"10.1016/j.jacc.2014.01.073"],[24730690,"ILAE official report: a practical clinical definition of epilepsy.","Epilepsia",2014,"Fisher et al.",6,[5],[14.63],17.16,10,9,9,[0,0,0,1,0,0,1,0,1,0,1,1,2,1,1,0],"10.1111/epi.12550"],[24836273,"Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial.","Lancet Oncol",2014,"Sartor et al.",2,[1,8,9],[17.16,12.65,12.65],17.16,11,9,8,[0,0,0,0,0,2,2,1,0,1,0,1,2,1,1,0],"10.1016/S1470-2045(14)70183-4"],[24998133,"Hypertrophic cardiomyopathy: 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Endocrine Society.","Diabetes Care",2013,"Seaquist et al.",7,[7],[14.58],17.1,14,10,7,[0,0,0,3,2,0,1,1,0,2,1,1,1,0,1,0],"10.2337/dc12-2480"],[26555945,"Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma: A Randomized, Multicenter, Open-Label Phase 3 Trial.","Transplantation",2016,"Geissler et al.",2,[4,1],[17.08,11.05],17.08,13,11,7,[0,0,0,0,0,1,2,1,0,0,0,0,1,5,1,2],"10.1097/TP.0000000000000965"],[26962904,"Declines in Unintended Pregnancy in the United States, 2008-2011.","N Engl J Med",2016,"Finer et al.",7,[9],[2.69],17.08,13,12,8,[0,0,0,0,0,1,5,0,3,2,0,0,0,1,0,0],"10.1056/NEJMsa1506575"],[28110982,"Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study.","Lancet",2017,"Ahmed et al.",5,[1,8,9],[17.08,17.08,17.08],17.08,12,11,7,[0,0,0,0,0,0,0,2,2,1,0,1,1,4,0,1],"10.1016/S0140-6736(16)32401-1"],[1714502,"The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of 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al.",5,[0,3],[11.38,6.77],17.06,12,9,9,[0,0,0,0,1,2,0,2,0,0,0,0,1,3,0,1],"10.1053/jlts.2000.6356"],[11374400,"Pregnancy outcome after cyclosporine therapy during pregnancy: a meta-analysis.","Transplantation",2001,"Bar Oz et al.",0,[17],[0.0],17.06,9,9,9,[0,0,0,1,1,2,0,2,2,0,0,0,0,0,1,0],"10.1097/00007890-200104270-00006"],[11389271,"A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates.","Pediatrics",2001,"Garland et al.",2,[2],[15.17],17.06,10,9,10,[1,2,0,3,0,1,1,1,0,0,0,0,0,0,0,0],"10.1542/peds.107.6.1431"],[11830325,"Development of dominant bile duct stenoses in patients with primary sclerosing cholangitis treated with ursodeoxycholic acid: outcome after endoscopic treatment.","J Hepatol",2002,"Stiehl et al.",3,[4],[17.06],17.06,9,9,9,[0,0,0,0,2,0,3,1,1,0,0,1,0,0,0,1],"10.1016/s0168-8278(01)00251-3"],[11932474,"Understanding the treatment preferences of seriously ill 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al.",2,[1,3],[17.06,17.06],17.06,12,9,11,[0,0,0,1,1,0,2,3,0,0,2,0,0,1,0,0],"10.1001/jamainternmed.2013.12738"],[24654740,"Competing risks and prognostic stages of cirrhosis: a 25-year inception cohort study of 494 patients.","Aliment Pharmacol Ther",2014,"D'Amico et al.",5,[4,1],[17.06,0.0],17.06,9,9,9,[0,0,0,0,0,0,2,1,0,1,1,0,0,3,1,0],"10.1111/apt.12721"],[24657840,"Proton pump inhibitors partially restore mucosal integrity in patients with proton pump inhibitor-responsive esophageal eosinophilia but not eosinophilic esophagitis.","Clin Gastroenterol Hepatol",2014,"van Rhijn et al.",5,[10,4,12],[14.44,17.06,14.44],17.06,9,9,9,[0,0,0,0,0,1,0,1,1,2,0,0,0,3,1,0],"10.1016/j.cgh.2014.02.037"],[25212648,"Laboratory measurement of the anticoagulant activity of the non-vitamin K oral anticoagulants.","J Am Coll Cardiol",2014,"Cuker et al.",6,[0],[15.17],17.06,13,9,9,[0,0,0,0,0,3,1,1,0,1,0,2,0,2,0,0],"10.1016/j.jacc.2014.05.065"],[25383558,"Multitarget therapy for induction treatment of lupus 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al.",2,[1],[17.06],17.06,9,9,9,[0,0,0,0,0,0,0,0,0,1,1,1,2,1,3,0],"10.1016/S1470-2045(17)30622-8"],[29298160,"Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.","N Engl J Med",2018,"Sullivan et al.",2,[11,14],[7.75,4.65],17.06,10,9,10,[0,0,0,0,0,0,0,0,0,1,1,0,1,2,4,1],"10.1056/nejmoa1703327"],[29449189,"Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial.","Lancet Oncol",2018,"de Boer et al.",2,[1,9,7],[17.06,17.06,0.0],17.06,11,9,9,[0,0,0,0,0,0,0,0,0,1,2,2,1,0,2,2],"10.1016/S1470-2045(18)30079-2"],[29567210,"Myocarditis in Patients Treated With Immune Checkpoint Inhibitors.","J Am Coll Cardiol",2018,"Mahmood et al.",5,[1,0],[11.38,8.47],17.06,9,9,9,[0,0,0,0,0,0,0,0,1,2,1,2,2,0,0,1],"10.1016/j.jacc.2018.02.037"],[29920657,"Anticoagulation for the long-term treatment of venous thromboembolism in people with 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al.",2,[0,7],[17.06,1.0],17.06,17,11,8,[0,0,0,0,0,0,0,0,0,0,3,1,1,3,3,2],"10.1016/j.jacc.2019.03.013"],[30948284,"Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial.","Lancet",2019,"Duhig et al.",2,[9,0,8],[14.44,6.77,1.0],17.06,12,9,9,[0,0,0,0,0,0,0,0,1,2,0,2,1,2,1,0],"10.1016/S0140-6736(18)33212-4"],[31825192,"Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer.","N Engl J Med",2020,"Modi et al.",2,[1,3],[17.06,2.69],17.06,10,9,9,[0,0,0,0,0,0,0,0,0,2,2,1,1,2,0,2],"10.1056/NEJMoa1914510"],[36661037,"Locoregional Failure During and After Short-course Radiotherapy Followed by Chemotherapy and Surgery Compared With Long-course Chemoradiotherapy and Surgery: A 5-Year Follow-up of the RAPIDO Trial.","Ann Surg",2023,"Dijkstra et al.",2,[1,4],[17.04,17.04],17.04,11,11,11,[0,0,0,0,0,0,0,0,0,0,0,0,0,5,5,1],"10.1097/SLA.0000000000005799"],[37364790,"A multisociety Delphi 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randomized trial comparing four thrombolytic strategies for acute myocardial infarction.","N Engl J Med",1993,"GUSTO investigators",2,[0],[14.69],16.79,15,10,7,[1,1,1,0,0,0,0,1,1,0,1,0,2,2,1,0],"10.1056/NEJM199309023291001"],[8656441,"Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. 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al.",2,[7,11],[12.24,2.69],16.79,13,8,8,[1,1,2,1,1,1,0,0,1,0,0,1,0,0,0,1],"10.1002/art.20256"],[15578509,"Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma < or =4 cm.","Gastroenterology",2004,"Lin et al.",2,[1,4],[16.79,16.79],16.79,16,8,10,[0,2,0,0,2,2,1,0,1,0,1,1,1,1,0,0],"10.1053/j.gastro.2004.09.003"],[15616758,"Assessment of fracture risk.","Osteoporos Int",2005,"Kanis et al.",6,[13,7],[11.84,11.84],16.79,10,8,8,[1,1,1,0,0,1,1,0,0,1,1,1,0,1,0,0],"10.1007/s00198-004-1780-5"],[16135487,"Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients--a Dutch colorectal cancer group study.","J Clin Oncol",2005,"Peeters et al.",7,[4,1,13],[16.79,16.79,0.0],16.79,14,8,8,[0,2,1,0,2,0,1,2,0,2,1,0,0,1,1,0],"10.1200/JCO.2005.14.779"],[16574519,"High prevalence of asymptomatic vertebral fractures in post-menopausal women receiving chronic glucocorticoid therapy: a cross-sectional outpatient study.","Bone",2006,"Angeli et al.",5,[13],[13.81],16.79,12,8,8,[0,1,1,1,0,0,3,0,0,0,1,1,1,1,0,1],"10.1016/j.bone.2006.02.005"],[19065676,"Systematic review of randomized trials for hepatocellular carcinoma treated with percutaneous ablation therapies.","Hepatology",2009,"Cho et al.",1,[1,4],[16.79,16.79],16.79,14,8,10,[0,1,1,0,1,2,1,1,1,0,0,1,0,1,0,0],"10.1002/hep.22648"],[19280622,"Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naïve patients is rare through 5 years of therapy.","Hepatology",2009,"Tenney et al.",7,[2,4],[16.79,14.28],16.79,12,8,8,[1,1,0,0,0,3,1,1,1,0,1,0,0,1,1,0],"10.1002/hep.22841"],[19853947,"Aspirin for primary prevention of cardiovascular events in patients with diabetes: A meta-analysis.","Diabetes Res Clin Pract",2010,"Zhang et al.",0,[0,7],[11.84,7.89],16.79,11,8,8,[1,1,1,2,1,0,1,2,0,1,0,0,0,0,0,1],"10.1016/j.diabres.2009.09.029"],[20005174,"Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial.","Lancet Oncol",2010,"Albain et al.",5,[1],[16.79],16.79,12,8,8,[2,0,1,1,1,3,0,0,1,0,0,1,0,1,0,1],"10.1016/S1470-2045(09)70314-6"],[21353334,"A double-blind, randomized controlled trial of clobetasol versus pimecrolimus in patients with vulvar lichen sclerosus.","J Am Acad Dermatol",2011,"Goldstein et al.",2,[9],[8.97],16.79,10,10,7,[0,1,1,1,1,0,0,0,0,1,0,1,1,1,0,2],"10.1016/j.jaad.2010.06.011"],[23523418,"Preoperative use of anti-TNF therapy and postoperative complications in inflammatory bowel diseases: a meta-analysis.","J Crohns Colitis",2013,"Billioud et al.",0,[4],[16.79],16.79,9,8,8,[0,0,0,1,1,1,1,1,1,1,1,0,0,0,1,0],"10.1016/j.crohns.2013.01.014"],[1999029,"Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure.","Circulation",1991,"Mancini et al.",5,[0],[16.74],16.74,12,11,6,[0,1,2,1,0,0,1,0,1,1,1,1,0,2,0,0],"10.1161/01.cir.83.3.778"],[11213005,"Venous thromboembolism in pregnancy and the puerperium: incidence and additional risk factors from a London perinatal database.","BJOG",2001,"Simpson et al.",5,[0,9],[13.38,12.32],16.74,11,10,8,[0,2,1,1,0,1,0,3,2,0,0,0,0,0,0,0],"10.1111/j.1471-0528.2001.00004.x"],[16009685,"Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine.","Gut",2005,"Kandiel et al.",0,[4,1,10],[14.84,1.0,0.0],16.74,10,10,8,[2,3,0,2,0,0,1,1,0,0,0,0,0,1,0,0],"10.1136/gut.2004.049460"],[16769986,"Postoperative radiotherapy for stage II or III non-small-cell lung cancer using the surveillance, epidemiology, and end results database.","J Clin Oncol",2006,"Lally et al.",5,[1,3],[16.74,16.74],16.74,10,10,8,[0,0,3,0,3,0,1,0,0,0,0,1,1,0,1,0],"10.1200/JCO.2005.04.6110"],[18723437,"Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations.","Am J Respir Crit Care Med",2008,"Seemungal et al.",2,[3],[16.74],16.74,12,10,9,[1,2,2,0,1,0,3,1,0,0,0,0,0,0,0,0],"10.1164/rccm.200801-145OC"],[18844620,"Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial.","Am J Gastroenterol",2008,"Marion et al.",5,[4],[16.74],16.74,11,10,9,[1,0,3,2,2,0,0,0,1,0,1,0,0,0,0,0],"10.1111/j.1572-0241.2008.01934.x"],[19106348,"Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists.","Am J Health Syst Pharm",2009,"Rybak et al.",4,[2],[13.38],16.74,11,10,8,[2,0,2,0,1,2,1,0,0,2,0,0,0,0,0,0],"10.2146/ajhp080434"],[19174792,"Effect of a probiotic preparation (VSL#3) on induction and maintenance of remission in children with ulcerative colitis.","Am J Gastroenterol",2009,"Miele et al.",2,[4],[16.74],16.74,11,10,8,[3,2,0,0,1,0,0,2,0,2,0,0,0,1,0,0],"10.1038/ajg.2008.118"],[19422443,"Catheter-directed thrombolysis vs. anticoagulant therapy alone in deep vein thrombosis: results of an open randomized, controlled trial reporting on short-term patency.","J Thromb Haemost",2009,"Enden et al.",2,[0],[16.74],16.74,11,10,8,[2,2,2,1,0,2,0,0,0,0,2,0,0,0,0,0],"10.1111/j.1538-7836.2009.03464.x"],[20171676,"Gadolinium enhanced magnetic resonance urography for upper urinary tract malignancy.","J Urol",2010,"Takahashi et al.",5,[8,1],[16.74,15.87],16.74,14,11,6,[0,2,2,0,1,0,0,0,0,1,2,1,1,2,2,0],"10.1016/j.juro.2009.12.031"],[20924367,"Diagnosis and management of iron deficiency anemia in patients with IBD.","Nat Rev Gastroenterol Hepatol",2010,"Stein et al.",6,[4,10,7],[12.95,8.47,4.65],16.74,11,10,9,[0,0,0,1,2,1,0,0,0,0,0,0,1,4,2,0],"10.1038/nrgastro.2010.151"],[22621627,"Effectiveness of long-acting reversible contraception.","N Engl J Med",2012,"Winner et al.",5,[9],[8.47],16.74,13,10,8,[0,0,0,1,0,0,2,3,3,1,0,0,0,0,1,0],"10.1056/NEJMoa1110855"],[24631577,"Nonselective β blockers increase risk for hepatorenal syndrome and death in patients with cirrhosis and spontaneous bacterial peritonitis.","Gastroenterology",2014,"Mandorfer et al.",5,[4,2,8],[16.74,1.0,1.0],16.74,10,10,8,[0,0,0,0,0,0,3,2,0,1,2,0,1,0,1,0],"10.1053/j.gastro.2014.03.005"],[25092278,"Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy.","Circulation",2014,"Chan et al.",2,[0],[16.74],16.74,14,10,8,[0,0,0,0,0,0,1,0,0,3,2,1,0,4,0,1],"10.1161/CIRCULATIONAHA.113.007094"],[25485720,"Effects of blood pressure lowering on outcome incidence in hypertension: 4. 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al.",6,[0],[9.8],16.72,20,12,6,[3,3,2,1,1,1,0,1,0,0,0,0,0,1,1,0],"10.1016/S0140-6736(09)61525-7"],[24325356,"Somatic mutations of calreticulin in myeloproliferative neoplasms.","N Engl J Med",2013,"Klampfl et al.",7,[10],[9.86],16.7,11,11,7,[0,0,0,2,0,4,1,1,0,1,1,1,0,0,0,0],"10.1056/NEJMoa1311347"],[25814232,"New perspectives on the prevalence of hypertrophic cardiomyopathy.","J Am Coll Cardiol",2015,"Semsarian et al.",6,[0],[16.7],16.7,17,11,7,[0,0,0,0,0,2,1,0,0,1,2,1,0,4,0,2],"10.1016/j.jacc.2015.01.019"],[19770739,"Intra-aortic balloon counterpulsation in patients with acute myocardial infarction complicated by cardiogenic shock: the prospective, randomized IABP SHOCK Trial for attenuation of multiorgan dysfunction syndrome.","Crit Care Med",2010,"Prondzinsky et al.",2,[0],[16.68],16.68,12,11,8,[0,3,0,0,2,0,0,0,0,0,2,1,0,0,3,0],"10.1097/CCM.0b013e3181b78671"],[26422722,"Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis.","N Engl J Med",2015,"Lebwohl et 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stroke according to stroke subtype and medical history: the PROGRESS Trial.","Stroke",2004,"Chapman et al.",2,[0,5],[16.62,6.48],16.62,12,10,7,[2,1,1,2,0,0,0,0,1,0,0,1,0,0,2,1],"10.1161/01.STR.0000106480.76217.6F"],[15193690,"The histologic basis of late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy.","J Am Coll Cardiol",2004,"Moon et al.",7,[0],[16.62],16.62,10,10,7,[1,0,0,2,0,1,2,1,0,1,1,0,0,0,0,1],"10.1016/j.jacc.2004.03.035"],[16288118,"Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study.","J Natl Cancer Inst",2005,"Fisher et al.",2,[1],[12.13],16.62,11,10,7,[2,1,2,1,1,0,0,0,2,0,1,0,0,1,0,0],"10.1093/jnci/dji372"],[16761103,"A new definition of Genetic Counseling: National Society of Genetic Counselors' Task Force report.","J Genet Couns",2006,"Resta et al.",7,[],[],16.62,10,10,7,[0,0,0,0,1,2,1,1,0,2,1,1,1,0,0,0],"10.1007/s10897-005-9014-3"],[17108343,"Correction 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enteral nutrition, provided within 24 h of injury or intensive care unit admission, significantly reduces mortality in critically ill patients: a meta-analysis of randomised controlled trials.","Intensive Care Med",2009,"Doig et al.",0,[13],[1.41],16.62,17,10,8,[3,0,1,2,0,2,1,1,0,1,0,0,0,1,0,0],"10.1007/s00134-009-1664-4"],[20093278,"Influence of smoking cessation after diagnosis of early stage lung cancer on prognosis: systematic review of observational studies with meta-analysis.","BMJ",2010,"Parsons et al.",0,[1,3],[14.1,10.87],16.62,13,10,7,[1,0,4,0,1,2,0,0,1,1,2,0,1,0,0,0],"10.1136/bmj.b5569"],[20688032,"Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy.","J Am Coll Cardiol",2010,"O'Hanlon et al.",3,[0],[16.62],16.62,17,10,7,[2,0,0,2,1,1,1,2,0,1,0,1,0,0,0,0],"10.1016/j.jacc.2010.05.010"],[21316752,"The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind 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National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network.","N Engl J Med",1996,"Iams et al.",5,[9],[16.6],16.6,10,9,8,[1,1,0,1,0,0,0,0,1,2,0,0,0,1,0,2],"10.1056/NEJM199602293340904"],[8995086,"A prediction rule to identify low-risk patients with community-acquired pneumonia.","N Engl J Med",1997,"Fine et al.",5,[2,3],[16.6,16.6],16.6,10,9,9,[1,2,1,1,1,0,0,0,1,0,2,0,0,0,0,0],"10.1056/NEJM199701233360402"],[9375704,"Acute renal failure after coronary intervention: incidence, risk factors, and relationship to mortality.","Am J Med",1997,"McCullough et al.",7,[8,0],[9.02,6.16],16.6,15,9,9,[1,5,2,2,0,0,0,0,1,1,0,1,0,0,0,0],"10.1016/s0002-9343(97)00150-2"],[9576405,"Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. 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Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group.","Lancet",2000,"Bellomo et al.",2,[8],[7.22],16.6,14,9,9,[1,0,2,0,0,2,1,1,3,1,0,0,0,0,0,0],"10.1016/s0140-6736(00)03495-4"],[11463010,"Three months versus one year of oral anticoagulant therapy for idiopathic deep venous thrombosis. Warfarin Optimal Duration Italian Trial Investigators.","N Engl J Med",2001,"Agnelli et al.",2,[0],[16.6],16.6,10,9,8,[2,1,1,0,0,1,0,0,1,1,3,0,0,0,0,0],"10.1056/NEJM200107193450302"],[11496852,"Cerebral sinovenous thrombosis in children.","N Engl J Med",2001,"deVeber et al.",7,[0,5],[16.6,11.38],16.6,10,9,9,[3,2,1,0,0,0,0,0,0,1,0,1,0,1,0,1],"10.1056/NEJM200108093450604"],[11762651,"Venous thromboembolism during pregnancy: a retrospective study of enoxaparin safety in 624 pregnancies.","BJOG",2001,"Lepercq et al.",5,[0,9,10],[16.6,6.77,3.25],16.6,10,9,8,[0,2,1,2,0,1,0,1,0,0,1,0,0,0,0,1],"10.1111/j.1471-0528.2003.00272.x"],[11801819,"Assessing pain in critically ill sedated patients by using a behavioral pain scale.","Crit Care Med",2001,"Payen et al.",5,[5,6],[5.29,5.29],16.6,9,9,8,[0,1,2,1,0,0,0,1,0,2,0,1,0,1,0,0],"10.1097/00003246-200112000-00004"],[11932655,"Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical 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reduction and secondary prevention of stroke and other vascular events: a systematic review.","Stroke",2003,"Rashid et al.",0,[0,5],[16.6,9.17],16.6,16,9,8,[3,2,1,0,0,1,0,1,1,0,0,0,0,0,0,1],"10.1161/01.STR.0000092488.40085.15"],[14657067,"Valvular dysfunction and carotid, subclavian, and coronary artery disease in survivors of hodgkin lymphoma treated with radiation therapy.","JAMA",2003,"Hull et al.",5,[0,1,10],[8.47,16.6,1.0],16.6,9,9,8,[0,1,2,1,0,2,0,0,0,0,1,0,1,0,0,1],"10.1001/jama.290.21.2831"],[14770429,"The natural history of incidentally detected small renal masses.","Cancer",2004,"Volpe et al.",5,[1,8],[16.6,16.6],16.6,10,9,8,[0,0,0,0,0,1,1,2,1,3,0,0,0,1,1,0],"10.1002/cncr.20025"],[15052249,"Prognostic value of gated myocardial perfusion SPECT.","J Nucl Cardiol",2004,"Shaw et al.",6,[0],[16.6],16.6,10,9,8,[2,2,1,1,0,0,1,0,0,1,0,1,0,0,0,0],"10.1016/j.nuclcard.2003.12.004"],[15224277,"Long-term follow-up after polypectomy treatment for adenoma-like dysplastic lesions in 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randomised controlled trial.","Lancet",2007,"Keech et al.",2,[15,7,0],[4.65,16.6,7.97],16.6,11,9,8,[0,0,1,3,1,1,0,0,2,0,0,1,0,1,0,0],"10.1016/S0140-6736(07)61607-9"],[18084017,"Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology.","Eur Heart J",2008,"Schroeder et al.",6,[0],[16.6],16.6,10,9,8,[1,1,1,1,0,0,0,3,0,0,0,1,0,0,1,0],"10.1093/eurheartj/ehm544"],[18177778,"Epidemiology and causes of preterm birth.","Lancet",2008,"Goldenberg et al.",6,[9],[14.06],16.6,11,9,8,[1,0,0,0,0,3,1,1,0,1,1,1,0,0,0,0],"10.1016/S0140-6736(08)60074-4"],[18254066,"Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection.","Cochrane Database Syst Rev",2008,"Hollier et al.",1,[2,9,8],[16.6,14.06,10.83],16.6,10,9,8,[0,0,1,0,0,1,2,1,0,1,0,0,0,0,2,1],"10.1002/14651858.CD004946.pub2"],[18514729,"Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial.","Lancet",2008,"Janssens et al.",2,[7,11,17],[16.6,16.6,16.6],16.6,10,9,8,[1,1,1,0,0,1,3,0,0,1,0,1,0,0,0,0],"10.1016/S0140-6736(08)60799-0"],[18558882,"Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis.","Clin Infect Dis",2008,"Reed et al.",5,[2,3,15],[14.06,1.0,0.0],16.6,9,9,8,[1,0,1,2,1,0,1,0,1,0,0,0,0,0,2,0],"10.1086/589857"],[18617641,"Portopulmonary hypertension: survival and prognostic factors.","Am J Respir Crit Care Med",2008,"Le Pavec et al.",5,[0,3,4],[11.58,11.58,4.65],16.6,11,9,8,[1,0,0,2,2,2,0,1,0,0,0,0,0,1,1,0],"10.1164/rccm.200804-613OC"],[18757948,"Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38.","Circulation",2008,"Wiviott et al.",2,[7,0],[2.69,16.6],16.6,17,11,7,[3,1,2,5,1,1,1,0,0,0,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.108.791061"],[19015471,"Enteral nutrition and the risk of mortality and infectious complications in patients with severe acute pancreatitis: a meta-analysis of randomized trials.","Arch Surg",2008,"Petrov et al.",0,[4],[16.6],16.6,11,9,8,[2,0,2,0,0,0,1,0,0,1,0,0,0,1,1,2],"10.1001/archsurg.143.11.1111"],[19118063,"O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.","Clin Cancer Res",2009,"Kulke et al.",7,[1],[16.6],16.6,10,9,8,[1,2,1,1,2,1,1,0,0,0,0,0,0,0,0,0],"10.1158/1078-0432.CCR-08-1476"],[19132789,"A safety assessment of tumor necrosis factor antagonists during pregnancy: a review of the Food and Drug Administration database.","J Rheumatol",2009,"Carter et al.",7,[9,17],[1.0,0.0],16.6,9,9,8,[3,0,0,1,1,0,1,1,0,0,0,0,1,0,1,0],"10.3899/jrheum.080545"],[19209168,"Histopathologic variability in children with eosinophilic esophagitis.","Am J Gastroenterol",2009,"Shah et al.",7,[4,10],[16.6,12.16],16.6,9,9,8,[0,0,1,1,0,0,1,1,0,0,0,0,0,2,2,1],"10.1038/ajg.2008.117"],[19384117,"Ovarian conservation at the time of hysterectomy and long-term health outcomes in the nurses' health study.","Obstet Gynecol",2009,"Parker et al.",5,[1,0,13],[6.77,2.69,1.0],16.6,9,9,8,[0,1,0,0,1,2,1,0,1,0,1,2,0,0,0,0],"10.1097/AOG.0b013e3181a11c64"],[19454404,"Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group.","Ann Rheum Dis",2009,"Rudwaleit et al.",4,[11,13],[16.6,16.6],16.6,11,9,8,[1,3,1,2,0,0,1,0,1,0,2,0,0,0,0,0],"10.1136/ard.2009.110767"],[19737568,"Factors that predict response of patients with hepatitis B e antigen-positive chronic hepatitis B to 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al.",2,[11],[16.6],16.6,10,9,8,[2,1,2,1,1,0,0,0,1,0,0,0,0,0,1,0],"10.1002/art.27431"],[20230416,"Hormone replacement therapy and the risk of venous thromboembolism: a population-based study.","J Thromb Haemost",2010,"Renoux et al.",5,[0],[15.17],16.6,9,9,8,[2,0,0,0,1,0,1,0,0,0,1,1,0,2,1,0],"10.1111/j.1538-7836.2010.03839.x"],[20231231,"Duration of dual antiplatelet therapy after implantation of drug-eluting stents.","N Engl J Med",2010,"Park et al.",2,[0],[16.6],16.6,11,9,8,[1,3,1,1,0,2,1,0,0,0,0,1,0,0,0,0],"10.1056/NEJMoa1001266"],[20238336,"Benzodiazepines for alcohol withdrawal.","Cochrane Database Syst Rev",2010,"Amato et al.",0,[5,6],[2.69,14.63],16.6,9,9,8,[0,2,1,0,1,1,0,1,0,0,0,0,0,2,0,1],"10.1002/14651858.CD005063.pub3"],[20483498,"Incidence of hepatocellular carcinoma in chronic hepatitis B patients receiving nucleos(t)ide therapy: a systematic review.","J Hepatol",2010,"Papatheodoridis et al.",1,[4,2,1],[16.6,9.77,6.77],16.6,10,9,8,[1,2,0,0,0,2,0,0,0,0,1,0,1,2,1,0],"10.1016/j.jhep.2010.02.035"],[20609775,"Recalibration of the revised cardiac risk index in lung resection candidates.","Ann Thorac Surg",2010,"Brunelli et al.",5,[3,0],[16.6,0.0],16.6,10,9,8,[0,0,1,1,0,2,1,0,0,0,1,0,0,0,2,1],"10.1016/j.athoracsur.2010.03.042"],[20616173,"Histopathologic classification of ANCA-associated glomerulonephritis.","J Am Soc Nephrol",2010,"Berden et al.",7,[8],[12.16],16.6,11,9,9,[0,1,0,0,1,3,0,1,0,0,2,0,0,1,1,0],"10.1681/ASN.2010050477"],[20619448,"Telemonitoring and self-management in the control of hypertension (TASMINH2): a randomised controlled trial.","Lancet",2010,"McManus et al.",2,[0],[16.6],16.6,12,9,8,[0,3,1,1,0,0,0,0,1,0,1,0,0,2,0,1],"10.1016/S0140-6736(10)60964-6"],[20650437,"Real-time ultrasound guidance facilitates femoral arterial access and reduces vascular complications: FAUST (Femoral Arterial Access With Ultrasound Trial).","JACC Cardiovasc Interv",2010,"Seto et al.",2,[0],[10.26],16.6,12,9,8,[1,1,2,1,0,0,0,0,2,0,0,0,0,0,3,1],"10.1016/j.jcin.2010.04.015"],[20667520,"Myocardial scar visualized by cardiovascular magnetic resonance imaging predicts major adverse events in patients with hypertrophic cardiomyopathy.","J Am Coll Cardiol",2010,"Bruder et al.",7,[0],[16.6],16.6,14,9,8,[3,0,0,2,0,1,1,1,0,0,1,1,0,0,0,0],"10.1016/j.jacc.2010.05.007"],[20687069,"Physical methods for preventing deep vein thrombosis in stroke.","Cochrane Database Syst Rev",2010,"Naccarato et al.",0,[0,5,3],[16.6,7.75,0.0],16.6,9,9,8,[0,1,1,3,0,1,0,1,0,0,1,0,0,0,0,1],"10.1002/14651858.CD001922.pub3"],[20711074,"Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis.","Crit Care Med",2010,"Marik et al.",0,[4],[9.77],16.6,11,9,8,[0,0,1,2,0,0,2,0,1,1,0,0,1,1,0,0],"10.1097/CCM.0b013e3181f17adf"],[20821360,"Small-bowel capsule endoscopy diagnoses early and advanced neoplasms in asymptomatic patients with Lynch syndrome.","Endoscopy",2010,"Saurin et al.",5,[1,4,7],[12.63,16.6,10.83],16.6,12,9,11,[0,0,1,2,2,0,1,0,0,1,1,0,1,0,0,0],"10.1055/s-0030-1255742"],[20869890,"Comparison of surveillance versus aortic endografting for small aneurysm repair (CAESAR): results from a randomised trial.","Eur J Vasc Endovasc Surg",2011,"Cao et al.",2,[0],[16.6],16.6,12,9,8,[0,0,0,2,0,1,0,1,2,0,0,1,2,2,0,0],"10.1016/j.ejvs.2010.08.026"],[20876709,"Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments.","Diabetes Care",2010,"Tesfaye et al.",6,[7,5],[16.6,3.25],16.6,10,9,8,[2,0,0,1,0,0,0,3,1,0,0,1,0,1,0,1],"10.2337/dc10-1303"],[20888436,"A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease.","Clin Gastroenterol Hepatol",2011,"Kotlyar et al.",1,[1,4,10],[0.0,16.6,0.0],16.6,9,9,8,[0,1,0,1,1,0,3,1,1,0,0,0,0,1,0,0],"10.1016/j.cgh.2010.09.016"],[21115133,"Patients with nondysplastic Barrett's esophagus have low risks for developing 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Preventi",7,[6],[14.06],16.6,10,9,8,[0,2,0,2,0,2,0,0,0,0,0,1,1,1,1,0],""],[22550315,"Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: combined results from two phase III trials.","Ann Rheum Dis",2012,"Manzi et al.",3,[11],[16.6],16.6,12,9,8,[0,0,2,0,0,1,0,1,1,0,1,0,0,0,2,2],"10.1136/annrheumdis-2011-200831"],[22743304,"Identification of causative foods in children with eosinophilic esophagitis treated with an elimination diet.","J Allergy Clin Immunol",2012,"Spergel et al.",5,[12,4,10],[14.06,12.65,10.26],16.6,9,9,8,[0,0,2,2,0,1,1,0,0,1,0,0,0,1,1,0],"10.1016/j.jaci.2012.05.021"],[22873531,"Tofacitinib or adalimumab versus placebo in rheumatoid arthritis.","N Engl J Med",2012,"van Vollenhoven et al.",2,[11],[16.6],16.6,10,9,8,[0,0,0,1,2,1,0,2,1,0,0,0,0,1,1,0],"10.1056/NEJMoa1112072"],[22892060,"Hormone replacement therapy after breast cancer: 10 year follow up of the 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al.",2,[4,0],[16.6,10.26],16.6,11,9,8,[0,0,0,0,0,1,2,0,1,0,2,0,0,2,1,1],"10.1002/hep.27546"],[25400870,"Endoscopic submucosal dissection vs endoscopic mucosal resection for early gastric cancer: A meta-analysis.","World J Gastrointest Endosc",2014,"Facciorusso et al.",7,[1,4],[16.6,16.6],16.6,9,9,8,[0,0,0,0,2,0,0,1,1,1,1,0,0,0,1,2],"10.4253/wjge.v6.i11.555"],[25514302,"Entecavir vs lamivudine for prevention of hepatitis B virus reactivation among patients with untreated diffuse large B-cell lymphoma receiving R-CHOP chemotherapy: a randomized clinical trial.","JAMA",2014,"Huang et al.",2,[2,4,1],[12.16,10.83,4.04],16.6,10,9,8,[0,0,0,0,0,0,3,1,1,1,1,1,0,0,2,0],"10.1001/jama.2014.15704"],[25732161,"Paclitaxel Plus Carboplatin Versus Paclitaxel Plus Cisplatin in Metastatic or Recurrent Cervical Cancer: The Open-Label Randomized Phase III Trial JCOG0505.","J Clin Oncol",2015,"Kitagawa et al.",2,[1,9],[16.6,16.6],16.6,12,9,8,[0,0,0,0,0,0,2,0,1,1,0,0,2,2,2,2],"10.1200/JCO.2014.58.4391"],[26282644,"Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center.","J Clin Oncol",2015,"Horvat et al.",5,[1,14],[16.6,3.74],16.6,10,9,9,[0,0,0,0,0,0,1,1,3,1,1,0,1,2,0,0],"10.1200/JCO.2015.60.8448"],[26398070,"Intravascular Complications of Central Venous Catheterization by Insertion Site.","N Engl J Med",2015,"Parienti et al.",2,[2,0],[9.77,4.09],16.6,10,9,8,[0,0,0,0,0,1,2,1,0,1,0,0,2,0,2,1],"10.1056/NEJMoa1500964"],[26657901,"Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database.","Gut",2017,"Møller et al.",5,[1,7,9],[16.6,9.02,4.65],16.6,10,9,8,[0,0,0,0,0,0,0,1,2,1,2,1,0,1,0,1],"10.1136/gutjnl-2015-309675"],[26834067,"Randomized Trial of Hepatic Artery Embolization for Hepatocellular Carcinoma Using Doxorubicin-Eluting Microspheres Compared With Embolization With Microspheres Alone.","J Clin Oncol",2016,"Brown et al.",2,[1,4],[16.6,16.6],16.6,11,9,8,[0,0,0,0,0,0,3,1,0,2,1,1,1,0,2,0],"10.1200/JCO.2015.64.0821"],[26900641,"Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.","J Clin Endocrinol Metab",2016,"Aroda et al.",2,[7,10],[16.6,1.0],16.6,11,9,8,[0,0,0,0,0,0,1,1,1,2,0,1,0,3,0,1],"10.1210/jc.2015-3754"],[27050206,"Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.","N Engl J Med",2016,"Buckner et al.",2,[1,5],[16.6,16.6],16.6,9,9,8,[0,0,0,0,0,0,1,1,0,0,1,2,0,1,2,1],"10.1056/NEJMoa1500925"],[27158893,"Nicotine receptor partial agonists for smoking cessation.","Cochrane Database Syst Rev",2016,"Cahill et 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(Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial.","Lancet Oncol",2017,"Erlandsson et al.",2,[1,4],[16.6,16.6],16.6,12,9,9,[0,0,0,0,0,0,1,0,0,2,1,2,0,2,3,1],"10.1016/S1470-2045(17)30086-4"],[28249141,"Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia.","N Engl J Med",2017,"Kantarjian et al.",2,[10,1],[16.6,15.17],16.6,11,9,8,[0,0,0,0,0,0,1,0,1,1,0,0,1,4,1,2],"10.1056/NEJMoa1609783"],[28604169,"Health Effects of Overweight and Obesity in 195 Countries over 25 Years.","N Engl J Med",2017,"Afshin et al.",7,[7],[14.06],16.6,10,9,9,[0,0,0,0,0,0,0,1,1,3,1,0,0,1,1,2],"10.1056/NEJMoa1614362"],[29572291,"Impact of temporary methotrexate discontinuation for 2 weeks on immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis: a randomised clinical trial.","Ann Rheum Dis",2018,"Park et al.",2,[11,2,3],[10.83,5.29,1.9],16.6,12,9,8,[0,0,0,0,0,0,0,0,0,2,2,1,1,1,1,2],"10.1136/annrheumdis-2018-213222"],[30144434,"Risk of Hepatocellular Cancer in Patients With Non-Alcoholic Fatty Liver Disease.","Gastroenterology",2018,"Kanwal et al.",5,[4,1],[16.6,6.77],16.6,12,9,8,[0,0,0,0,0,0,0,0,0,1,2,1,1,2,1,2],"10.1053/j.gastro.2018.08.024"],[30326299,"Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-analysis.","Clin Gastroenterol Hepatol",2019,"Lee et al.",0,[4,7],[12.16,6.77],16.6,12,9,9,[0,0,0,0,0,0,0,0,0,1,2,1,2,1,2,1],"10.1016/j.cgh.2018.10.017"],[30543350,"Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.","JAMA Oncol",2019,"Bex et al.",2,[1,8],[16.6,16.6],16.6,10,9,7,[0,0,0,0,0,0,0,0,1,3,1,1,1,2,0,1],"10.1001/jamaoncol.2018.5543"],[17075010,"Hospital delays in reperfusion for ST-elevation myocardial infarction: implications when selecting a reperfusion strategy.","Circulation",2006,"Pinto et al.",7,[0],[16.57],16.57,18,13,5,[2,1,1,1,3,0,2,1,1,1,0,1,0,0,0,0],"10.1161/CIRCULATIONAHA.106.638353"],[15800226,"Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis.","N Engl J Med",2005,"Chimowitz et al.",2,[0,5],[16.55,16.55],16.55,17,10,8,[2,4,2,1,0,0,0,0,0,0,0,1,0,0,0,1],"10.1056/NEJMoa043033"],[17047219,"Fish intake, contaminants, and human health: evaluating the risks and the benefits.","JAMA",2006,"Mozaffarian et al.",6,[0,7],[14.66,6.2],16.55,14,10,10,[0,3,1,0,2,0,0,1,0,0,2,0,0,1,0,0],"10.1001/jama.296.15.1885"],[17253443,"Antidepressants for smoking cessation.","Cochrane Database Syst Rev",2007,"Hughes et al.",0,[0],[6.32],16.55,16,10,9,[1,2,4,0,1,1,0,1,0,0,0,0,0,0,0,0],"10.1002/14651858.CD000031.pub3"],[18785950,"Early Barrett's carcinoma with \"low-risk\" submucosal invasion: long-term results of endoscopic resection with a curative intent.","Am J Gastroenterol",2008,"Manner et al.",5,[1,4],[14.66,16.55],16.55,10,10,8,[0,0,0,1,2,0,0,0,0,1,0,1,3,2,0,0],"10.1111/j.1572-0241.2008.02083.x"],[18813052,"A rational approach to perioperative fluid management.","Anesthesiology",2008,"Chappell et al.",6,[2],[6.2],16.55,10,10,8,[0,0,1,0,0,0,4,1,2,0,0,0,1,1,0,0],"10.1097/ALN.0b013e3181863117"],[19001323,"Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: the Hoosier Oncology Group and U.S. Oncology.","J Clin Oncol",2008,"Hanna et al.",2,[1,3],[16.55,16.55],16.55,10,10,8,[0,0,4,0,2,1,0,0,0,1,0,1,1,0,0,0],"10.1200/JCO.2008.17.7840"],[23090347,"Electrocardiogram provides a continuous heart rate faster than oximetry during neonatal resuscitation.","Pediatrics",2012,"Katheria et al.",7,[0,17],[11.4,15.17],16.55,11,10,8,[0,0,0,0,3,1,1,0,0,0,0,0,0,1,3,1],"10.1542/peds.2012-0784"],[23549581,"Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial.","JAMA",2013,"Smith et al.",2,[5],[6.84],16.55,11,10,8,[0,0,0,3,1,1,0,2,0,2,1,0,0,0,0,0],"10.1001/jama.2013.2813"],[25985734,"Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease.","Gastroenterology",2015,"Charlton et al.",2,[4,2],[13.95,10.86],16.55,12,10,8,[0,0,0,0,0,3,3,3,0,1,1,0,0,1,0,0],"10.1053/j.gastro.2015.05.010"],[26943128,"Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants.","N Engl J Med",2016,"Perkin et al.",2,[12],[16.55],16.55,12,10,9,[0,0,0,0,0,0,2,1,0,1,3,0,0,1,0,2],"10.1056/NEJMoa1514210"],[28581356,"Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer.","N Engl J Med",2017,"von Minckwitz et al.",2,[1],[16.55],16.55,12,10,8,[0,0,0,0,0,0,0,1,2,2,1,0,0,3,2,0],"10.1056/NEJMoa1703643"],[28859947,"Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial.","Lancet",2017,"Giugliano et al.",2,[7],[16.05],16.55,13,12,7,[0,0,0,0,0,0,0,0,4,0,1,2,0,1,3,1],"10.1016/S0140-6736(17)32290-0"],[30057104,"Esomeprazole and aspirin in Barrett's oesophagus (AspECT): a randomised factorial trial.","Lancet",2018,"Jankowski et al.",2,[4,1],[16.55,12.76],16.55,10,10,8,[0,0,0,0,0,0,0,0,2,1,0,3,1,2,1,0],"10.1016/S0140-6736(18)31388-6"],[31679945,"Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study.","Lancet",2019,"Burtness et al.",2,[1],[16.55],16.55,11,10,8,[0,0,0,0,0,0,0,0,0,1,3,0,1,2,3,1],"10.1016/S0140-6736(19)32591-7"],[32174130,"Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction: Results From 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A randomized, double-blind, crossover study (M-PATHY).","Circulation",1999,"Maron et al.",2,[0],[16.53],16.53,22,11,6,[1,1,3,1,0,1,0,0,0,1,2,1,0,2,0,0],"10.1161/01.cir.99.22.2927"],[21606084,"Cardiac resynchronization therapy in patients undergoing atrioventricular junction ablation for permanent atrial fibrillation: a randomized trial.","Eur Heart J",2011,"Brignole et al.",2,[0],[16.53],16.53,28,14,5,[0,2,3,1,0,1,0,0,2,1,0,1,1,2,0,1],"10.1093/eurheartj/ehr162"],[18832524,"Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study.","Gut",2009,"Fidder et al.",5,[4],[16.51],16.51,11,11,8,[3,3,0,2,0,0,2,0,0,0,0,0,0,1,0,0],"10.1136/gut.2008.163642"],[26177572,"Systematic review: the effects of long-term proton pump inhibitor use on serum gastrin levels and gastric histology.","Aliment Pharmacol Ther",2015,"Lundell et al.",1,[1,4,2],[1.0,14.78,5.78],16.51,11,11,8,[0,0,0,0,0,0,3,0,0,0,0,1,0,2,4,1],"10.1111/apt.13324"],[32187462,"Two Phase 3 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al.",2,[7],[13.55],16.5,19,12,8,[2,0,1,0,0,2,0,1,2,0,1,1,0,1,0,2],"10.1056/NEJMoa020194"],[22253363,"Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010.","JAMA",2012,"Flegal et al.",7,[7],[15.24],16.48,15,11,10,[0,0,2,5,2,3,0,0,0,0,0,0,0,0,0,0],"10.1001/jama.2012.39"],[34555333,"Adjuvant atezolizumab after adjuvant chemotherapy in resected stage IB-IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase 3 trial.","Lancet",2021,"Felip et al.",3,[1,3],[16.48,15.94],16.48,11,11,9,[0,0,0,0,0,0,0,0,0,0,0,1,4,1,5,0],"10.1016/S0140-6736(21)02098-5"],[27247218,"Updating the American Society of Clinical Oncology Value Framework: Revisions and Reflections in Response to Comments Received.","J Clin Oncol",2016,"Schnipper et al.",7,[1],[14.32],16.47,37,34,3,[0,0,0,0,0,0,2,1,7,6,3,3,5,1,6,3],"10.1200/JCO.2016.68.2518"],[16302897,"Left ventricular-based cardiac stimulation post AV nodal ablation evaluation (the PAVE 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Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial.","Lancet",2015,"Long et al.",2,[1,14],[16.43,11.04],16.43,12,9,7,[0,0,0,0,0,1,1,0,2,1,1,1,1,1,3,0],"10.1016/S0140-6736(15)60898-4"],[27279544,"Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.","Lancet Oncol",2016,"Choueiri et al.",2,[1,8],[16.43,16.43],16.43,13,9,7,[0,0,0,0,0,2,2,2,1,1,1,2,1,1,0,0],"10.1016/S1470-2045(16)30107-3"],[22179539,"Heart disease and stroke statistics--2012 update: a report from the American Heart Association.","Circulation",2012,"Roger et al.",7,[0,5],[12.25,6.2],16.36,13,13,7,[0,0,7,3,1,0,0,0,0,1,0,0,0,1,0,0],"10.1161/CIR.0b013e31823ac046"],[7791837,"A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease. The Preoperative Transfusion in Sickle Cell Disease Study Group.","N Engl J Med",1995,"Vichinsky et al.",2,[10,17],[13.27,9.02],16.32,10,8,8,[1,0,1,1,2,0,1,1,0,1,1,0,0,0,0,0],"10.1056/NEJM199507273330402"],[8200250,"Double-blind crossover trial of metronidazole versus placebo in chronic unremitting pouchitis.","Dig Dis Sci",1994,"Madden et al.",2,[4],[16.32],16.32,10,8,10,[1,0,1,1,1,0,0,2,0,1,0,0,2,1,0,0],"10.1007/BF02093783"],[8489394,"A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992.","Arch Surg",1993,"Bradley",4,[4],[16.32],16.32,9,8,8,[0,1,1,0,2,1,1,0,0,1,0,0,0,1,1,0],"10.1001/archsurg.1993.01420170122019"],[9395428,"Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial.","N Engl J Med",1997,"Overgaard et al.",2,[1],[16.32],16.32,14,8,9,[3,0,1,1,2,1,1,0,0,0,0,0,0,2,2,0],"10.1056/NEJM199710023371401"],[9424975,"The clinical validity of normal compression ultrasonography in outpatients suspected of having deep venous thrombosis.","Ann Intern Med",1998,"Birdwell et al.",5,[0,11],[16.32,0.0],16.32,8,8,7,[1,1,1,0,0,0,0,1,1,1,1,0,0,1,0,0],"10.7326/0003-4819-128-1-199801010-00001"],[10348832,"AGA technical review on the evaluation and management of chronic diarrhea.","Gastroenterology",1999,"Fine et al.",6,[4],[6.77],16.32,8,8,8,[1,0,1,0,0,1,1,1,1,1,0,0,0,1,0,0],"10.1016/s0016-5085(99)70513-5"],[10891516,"Validity of a set of clinical criteria to rule out injury to the cervical spine in patients with blunt trauma. National Emergency X-Radiography Utilization Study Group.","N Engl J Med",2000,"Hoffman et al.",5,[13],[15.12],16.32,13,10,7,[1,0,1,1,0,0,1,0,5,1,0,0,0,1,2,0],"10.1056/NEJM200007133430203"],[11208851,"Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.","J Clin Oncol",2001,"Major et al.",7,[7],[2.69],16.32,12,8,8,[2,0,0,3,1,0,1,1,0,1,0,1,2,0,0,0],"10.1200/JCO.2001.19.2.558"],[11848723,"Surveillance for second primary colorectal cancer after adjuvant chemotherapy: an analysis of Intergroup 0089.","Ann Intern Med",2002,"Green et al.",5,[1,4],[16.32,16.32],16.32,13,8,10,[1,1,2,0,2,1,0,1,0,2,0,1,0,0,0,0],"10.7326/0003-4819-136-4-200202190-00005"],[11966499,"Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis.","Aliment Pharmacol Ther",2002,"Mimura et al.",3,[4],[16.32],16.32,10,8,8,[2,0,1,0,1,0,1,1,0,1,0,0,1,2,0,0],"10.1046/j.1365-2036.2002.01203.x"],[12093239,"Updated definitions of healthy ranges for serum alanine aminotransferase levels.","Ann Intern Med",2002,"Prati et al.",5,[4,2],[16.32,11.38],16.32,12,8,8,[0,3,0,1,0,2,1,1,1,0,0,1,0,1,0,0],"10.7326/0003-4819-137-1-200207020-00006"],[12231089,"Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus.","Am J Cardiol",2002,"Bhatt et al.",2,[7,0],[14.28,13.81],16.32,12,8,8,[2,1,2,1,0,0,0,0,0,1,1,0,1,1,0,0],"10.1016/s0002-9149(02)02567-5"],[12425546,"Comparison of endoscopic ultrasound-guided fine needle aspiration for focal pancreatic lesions in patients with normal parenchyma and chronic pancreatitis.","Am J Gastroenterol",2002,"Fritscher-Ravens et al.",5,[4],[16.32],16.32,8,8,8,[0,1,0,1,1,1,1,0,0,1,1,1,0,0,0,0],"10.1111/j.1572-0241.2002.07020.x"],[14613287,"Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy.","Arthritis Rheum",2003,"Van Staa et al.",2,[13],[16.32],16.32,9,8,8,[0,1,1,1,0,0,1,0,1,0,1,0,0,1,2,0],"10.1002/art.11283"],[15247190,"Iron, anaemia, and inflammatory bowel diseases.","Gut",2004,"Gasche et al.",6,[4,10,7],[16.32,6.77,1.0],16.32,8,8,8,[1,0,0,0,1,1,0,1,1,0,0,0,1,1,1,0],"10.1136/gut.2003.035758"],[15306601,"Chronic hepatitis B reactivation following infliximab therapy in Crohn's disease patients: need for primary prophylaxis.","Gut",2004,"Esteve et al.",7,[4,2],[16.32,7.22],16.32,12,8,8,[3,2,0,0,0,2,0,0,1,0,1,1,1,1,0,0],"10.1136/gut.2004.040675"],[15747071,"Long-term outcome of mesocolic and pelvic diverticular abscesses of the left colon: a prospective study of 73 cases.","Dis Colon Rectum",2005,"Ambrosetti et al.",5,[4,2],[16.32,0.0],16.32,8,8,8,[1,1,1,1,1,0,0,0,0,1,0,1,0,1,0,0],"10.1007/s10350-004-0853-z"],[15831922,"Epidemiology of gastro-oesophageal reflux disease: a systematic review.","Gut",2005,"Dent et al.",1,[4],[11.84],16.32,9,8,8,[0,1,0,1,1,1,0,0,0,1,0,2,0,1,1,0],"10.1136/gut.2004.051821"],[15948807,"Meta-analysis: role of Helicobacter pylori eradication in the prevention of peptic ulcer in NSAID users.","Aliment Pharmacol Ther",2005,"Vergara et al.",0,[2,4],[13.81,9.48],16.32,10,8,9,[1,1,2,1,0,1,2,0,0,1,1,0,0,0,0,0],"10.1111/j.1365-2036.2005.02444.x"],[16111955,"Diagnostic utility of peroral cholangioscopy for various bile-duct lesions.","Gastrointest Endosc",2005,"Fukuda et al.",5,[4,1],[16.32,9.02],16.32,9,8,8,[0,0,1,0,1,0,1,0,1,1,0,0,1,1,0,1],"10.1016/j.gie.2005.04.032"],[16243849,"Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study.","BMJ",2005,"Dove-Edwin et al.",5,[1,4,7],[16.32,16.32,6.77],16.32,11,8,11,[0,1,1,1,1,0,0,0,1,1,1,0,0,0,0,1],"10.1136/bmj.38606.794560.EB"],[16855265,"Trends in prevalence and outcome of heart failure with preserved ejection fraction.","N Engl 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al.",5,[14,0,7],[16.32,11.38,11.38],16.32,8,8,8,[0,1,1,1,1,1,0,0,0,0,1,0,0,1,1,0],"10.1086/511036"],[17548364,"Duplex ultrasonography, magnetic resonance angiography, and computed tomography angiography for diagnosis and assessment of symptomatic, lower limb peripheral arterial disease: systematic review.","BMJ",2007,"Collins et al.",1,[0],[16.32],16.32,9,8,8,[0,0,1,1,0,0,1,0,1,1,2,0,1,1,0,0],"10.1136/bmj.39217.473275.55"],[17613280,"A prospective, randomized trial of clear liquids versus low-fat solid diet as the initial meal in mild acute pancreatitis.","Clin Gastroenterol Hepatol",2007,"Jacobson et al.",2,[4],[16.32],16.32,9,8,8,[0,0,1,0,2,1,0,1,0,0,1,0,0,1,1,1],"10.1016/j.cgh.2007.04.012"],[17665429,"Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.","Arthritis Rheum",2007,"Mahr et al.",0,[0,11,5],[16.32,13.81,11.38],16.32,10,8,8,[1,1,0,0,0,1,0,0,1,1,2,0,1,0,1,0],"10.1002/art.22754"],[17893494,"Validation of the obesity surgery mortality risk score in a multicenter study proves it stratifies mortality risk in patients undergoing gastric bypass for morbid obesity.","Ann Surg",2007,"DeMaria et al.",5,[7],[16.32],16.32,12,8,10,[1,0,1,1,1,0,2,1,1,0,0,1,0,0,0,0],"10.1097/SLA.0b013e318157206e"],[18172030,"Implantable cardioverter-defibrillators in tetralogy of Fallot.","Circulation",2008,"Khairy et al.",5,[0,17],[16.32,10.26],16.32,21,10,7,[0,1,0,1,2,0,0,1,1,0,1,1,0,0,0,3],"10.1161/CIRCULATIONAHA.107.726372"],[18684197,"Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms: 'on' or 'off' proton pump inhibitor?","Am J Gastroenterol",2008,"Hemmink et al.",2,[4],[16.32],16.32,8,8,8,[0,0,0,1,0,0,1,1,1,0,1,1,0,1,1,0],"10.1111/j.1572-0241.2008.02033.x"],[19052048,"Effect of CT screening on smoking habits at 1-year follow-up in the Danish Lung Cancer Screening Trial (DLCST).","Thorax",2009,"Ashraf et al.",2,[1,3],[16.32,16.32],16.32,8,8,8,[0,1,1,1,1,1,1,0,0,0,0,0,0,1,1,0],"10.1136/thx.2008.102475"],[19058760,"Controlling hypertension and hypotension immediately post-stroke (CHHIPS): a randomised, placebo-controlled, double-blind pilot trial.","Lancet Neurol",2009,"Potter et al.",2,[0,5],[16.32,11.84],16.32,14,10,7,[0,2,2,2,0,0,0,1,1,0,0,0,0,1,1,2],"10.1016/S1474-4422(08)70263-1"],[19106083,"Genetic determinants of response to clopidogrel and cardiovascular events.","N Engl J Med",2009,"Simon et al.",7,[0],[14.28],16.32,17,10,7,[3,2,3,0,1,2,1,0,1,0,0,0,0,0,1,0],"10.1056/NEJMoa0808227"],[19298450,"Early hepatic artery thrombosis after liver transplantation: a systematic review of the incidence, outcome and risk factors.","Am J Transplant",2009,"Bekker et al.",1,[0],[1.0],16.32,8,8,8,[1,1,0,0,0,0,1,0,1,0,1,1,0,0,1,1],"10.1111/j.1600-6143.2008.02541.x"],[19307501,"Chemoradiotherapy in the management of locally advanced pancreatic carcinoma: a qualitative systematic review.","J Clin 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al.",2,[7],[3.1],16.32,12,8,9,[0,2,1,0,1,0,0,0,1,1,2,0,0,0,1,1],"10.1002/hep.23129"],[20206776,"Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial.","Lancet",2010,"Lassen et al.",2,[0],[16.32],16.32,9,8,8,[0,1,1,0,1,0,1,2,0,1,1,0,0,1,0,0],"10.1016/S0140-6736(09)62125-5"],[20463331,"An entirely subcutaneous implantable cardioverter-defibrillator.","N Engl J Med",2010,"Bardy et al.",3,[0],[13.81],16.32,15,10,7,[0,1,0,2,2,1,1,1,0,1,0,1,0,0,0,0],"10.1056/NEJMoa0909545"],[20558366,"Population trends in the incidence and outcomes of acute myocardial infarction.","N Engl J Med",2010,"Yeh et al.",5,[0],[16.32],16.32,13,10,7,[1,0,2,1,2,0,1,0,1,1,0,0,0,0,1,0],"10.1056/NEJMoa0908610"],[20635398,"Is sexual contact a major mode of hepatitis C virus transmission?","Hepatology",2010,"Tohme et al.",6,[2,9,4],[16.32,8.47,11.84],16.32,9,8,8,[0,1,1,1,1,1,0,0,0,1,2,0,0,0,0,1],"10.1002/hep.23808"],[21145828,"A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis.","J Hepatol",2011,"Ratziu et al.",2,[4,7],[16.32,1.0],16.32,13,8,10,[0,1,1,1,1,0,0,1,0,0,0,1,0,1,0,1],"10.1016/j.jhep.2010.08.030"],[21345104,"Point-of-care ultrasonography.","N Engl J Med",2011,"Moore et al.",6,[0,3],[2.69,2.69],16.32,10,8,8,[0,0,1,0,1,1,0,0,1,1,0,1,2,1,0,0],"10.1056/NEJMra0909487"],[21345487,"Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial.","Lancet",2011,"Malfertheiner et al.",2,[2],[16.32],16.32,10,8,8,[0,2,1,0,1,1,1,0,0,0,0,1,0,1,1,0],"10.1016/S0140-6736(11)60020-2"],[21646910,"A randomized controlled trial comparing lactulose, probiotics, and L-ornithine L-aspartate in treatment of minimal hepatic encephalopathy.","Eur J Gastroenterol Hepatol",2011,"Mittal et al.",2,[4,5,7],[16.32,11.38,11.38],16.32,9,8,8,[0,0,0,1,0,0,0,0,1,1,0,1,1,1,1,1],"10.1097/MEG.0b013e32834696f5"],[21676554,"External pelvic and vaginal irradiation versus vaginal irradiation alone as postoperative therapy in medium-risk endometrial carcinoma--a prospective randomized study.","Int J Radiat Oncol Biol Phys",2012,"Sorbe et al.",2,[1,9],[16.32,16.32],16.32,11,8,8,[0,0,0,2,0,1,2,1,0,0,1,1,1,0,1,0],"10.1016/j.ijrobp.2011.04.014"],[21793744,"Desensitization in HLA-incompatible kidney recipients and survival.","N Engl J Med",2011,"Montgomery et al.",3,[8],[2.69],16.32,10,8,8,[0,0,2,0,0,0,1,2,1,1,0,1,0,0,1,1],"10.1056/NEJMoa1012376"],[21802681,"Narrow-band imaging as an alternative to chromoendoscopy for the detection of dysplasia in long-standing inflammatory bowel disease: a prospective, randomized, crossover study.","Gastrointest Endosc",2011,"Pellisé et al.",2,[4,1],[16.32,6.77],16.32,10,8,10,[0,0,1,1,2,0,0,1,1,0,1,0,1,1,0,0],"10.1016/j.gie.2011.05.013"],[21844111,"Using the Edmonton obesity staging system to predict mortality in a population-representative cohort of people with overweight and obesity.","CMAJ",2011,"Padwal et al.",7,[7],[16.32],16.32,10,8,10,[0,0,0,0,0,1,1,1,1,3,0,1,1,0,1,0],"10.1503/cmaj.110387"],[22274684,"Lansoprazole for children with poorly controlled asthma: a randomized controlled trial.","JAMA",2012,"Holbrook et al.",2,[3,12],[4.65,2.69],16.32,9,8,8,[0,0,0,0,0,1,0,1,0,0,1,1,1,1,1,1],"10.1001/jama.2011.2035"],[22333950,"High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load.","Gastroenterology",2012,"Tseng et al.",7,[4,1,2],[16.32,6.2,11.38],16.32,10,8,8,[0,0,0,0,0,1,0,0,1,1,2,1,0,1,1,1],"10.1053/j.gastro.2012.02.007"],[22395225,"Efficacy of adalimumab rescue therapy in patients with chronic refractory pouchitis previously treated with infliximab: a case series.","Eur J Gastroenterol Hepatol",2012,"Barreiro-de Acosta et al.",5,[4],[16.32],16.32,10,8,9,[0,0,2,0,1,0,1,1,0,1,0,0,1,2,1,0],"10.1097/MEG.0b013e3283525a7b"],[23032615,"Predictors of locoregional recurrence after neoadjuvant chemotherapy: results from combined analysis of National Surgical Adjuvant Breast and Bowel Project B-18 and B-27.","J Clin Oncol",2012,"Mamounas et al.",0,[1],[16.32],16.32,12,8,9,[0,0,0,1,2,2,1,0,1,0,1,0,0,0,1,1],"10.1200/JCO.2011.40.8369"],[23335221,"Adjuvant therapy for high-grade, uterus-limited leiomyosarcoma: results of a phase 2 trial (SARC 005).","Cancer",2013,"Hensley et al.",3,[1,9],[16.32,13.81],16.32,10,8,8,[0,0,0,1,1,0,3,1,0,0,1,0,1,1,1,0],"10.1002/cncr.27942"],[24168956,"Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial.","Lancet",2014,"Smolen et al.",2,[11],[16.32],16.32,11,8,7,[0,0,0,2,1,1,0,1,1,1,1,0,0,1,0,0],"10.1016/S0140-6736(13)61751-1"],[24190934,"Diagnostic accuracy of placental growth factor in women with suspected preeclampsia: a prospective multicenter study.","Circulation",2013,"Chappell et al.",5,[9],[13.81],16.32,10,8,8,[0,0,0,0,0,1,0,1,1,0,0,1,1,1,1,1],"10.1161/CIRCULATIONAHA.113.003215"],[24276776,"Preoperative magnetic resonance imaging assessment of circumferential resection margin predicts disease-free survival and local recurrence: 5-year follow-up results of the MERCURY study.","J Clin Oncol",2014,"Taylor et al.",3,[1,4],[16.32,16.32],16.32,10,8,8,[0,0,0,0,0,0,1,1,0,1,1,0,1,2,2,1],"10.1200/JCO.2012.45.3258"],[25499873,"Use and outcomes associated with bridging during anticoagulation interruptions in patients with atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).","Circulation",2015,"Steinberg et 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al.",2,[4],[9.43],16.16,14,12,12,[0,0,0,0,0,0,0,0,0,0,0,0,0,0,3,9],"10.1056/NEJMoa2413258"],[16875966,"Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy.","J Am Coll Cardiol",2006,"Cannon et al.",0,[0],[14.17],16.14,27,13,6,[4,3,4,2,1,0,0,2,1,0,0,0,0,0,0,0],"10.1016/j.jacc.2006.04.070"],[17652294,"Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy.","JAMA",2007,"Maron et al.",7,[0],[16.08],16.08,33,13,5,[2,0,2,2,1,0,1,1,1,1,2,0,0,2,0,0],"10.1001/jama.298.4.405"],[7674529,"Exercise rehabilitation programs for the treatment of claudication pain. 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prophylaxis for prevention of venous thromboembolism in high-risk patients.","Cochrane Database Syst Rev",2008,"Kakkos et al.",0,[0,3],[7.33,1.0],16.07,15,10,8,[0,4,2,2,0,1,1,2,0,1,0,0,0,0,0,0],"10.1002/14651858.CD005258.pub2"],[19381076,"Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis.","AIDS",2009,"Attia et al.",0,[2,9,12],[16.07,16.07,16.07],16.07,12,10,7,[0,3,1,3,1,1,0,0,0,0,0,1,0,0,1,0],"10.1097/QAD.0b013e32832b7dca"],[20621900,"Extended-duration venous thromboembolism prophylaxis in acutely ill medical patients with recently reduced mobility: a randomized trial.","Ann Intern Med",2010,"Hull et al.",2,[0],[15.45],16.07,10,10,9,[1,1,2,0,0,0,0,1,0,3,1,0,0,1,0,0],"10.7326/0003-4819-153-1-201007060-00004"],[23902482,"A trial of intraoperative low-tidal-volume ventilation in abdominal surgery.","N Engl J Med",2013,"Futier et 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Canadian Inflammatory Bowel Disease Study Group.","N Engl J Med",1994,"Greenberg et al.",2,[4],[15.97],15.97,11,9,7,[2,1,0,0,0,1,2,1,0,1,0,0,0,2,1,0],"10.1056/NEJM199409293311303"],[8118029,"Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE.","Blood",1994,"Andrew et al.",7,[0,3,11],[14.63,1.9,1.0],15.97,10,9,7,[1,1,1,1,0,0,0,2,0,1,0,1,0,0,2,0],""],[8190152,"Exercise training and nutritional supplementation for physical frailty in very elderly people.","N Engl J Med",1994,"Fiatarone et al.",2,[7],[7.58],15.97,11,9,7,[0,0,2,2,0,1,0,0,1,0,1,2,0,1,0,1],"10.1056/NEJM199406233302501"],[8338289,"Risk for sustained amenorrhea in patients with systemic lupus erythematosus receiving intermittent pulse cyclophosphamide therapy.","Ann Intern Med",1993,"Boumpas et al.",2,[11],[11.05],15.97,9,9,7,[0,2,1,0,1,0,1,1,1,1,0,0,0,1,0,0],"10.7326/0003-4819-119-5-199309010-00003"],[8482443,"Mesalamine capsules for the treatment of active Crohn's disease: results of a 16-week trial. 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related to survival at six months in patients resuscitated from out-of-hospital ventricular fibrillation.","Resuscitation",2003,"Skrifvars et al.",5,[0],[15.97],15.97,11,9,7,[0,0,1,0,3,0,0,1,0,0,1,1,0,1,1,1],"10.1016/s0300-9572(03)00238-7"],[15051644,"Left cardiac sympathetic denervation in the management of high-risk patients affected by the long-QT syndrome.","Circulation",2004,"Schwartz et al.",7,[0,17],[13.47,2.69],15.97,17,9,7,[0,0,2,1,1,0,1,1,0,0,1,1,1,0,0,0],"10.1161/01.CIR.0000125523.14403.1E"],[15183623,"Comparison of surgery and compression with compression alone in chronic venous ulceration (ESCHAR study): randomised controlled trial.","Lancet",2004,"Barwell et al.",2,[0,14],[13.47,9.48],15.97,10,9,7,[1,1,0,1,1,1,0,0,0,2,0,0,0,1,2,0],"10.1016/S0140-6736(04)16353-8"],[16403930,"International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis.","JAMA",2006,"Bhatt et 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French Society of Endocrinology Consensus.","Ann Endocrinol (Paris)",2008,"Tabarin et al.",1,[7,1],[15.97,13.93],15.97,11,9,8,[1,0,0,0,0,1,2,2,0,2,0,1,0,1,1,0],"10.1016/j.ando.2008.09.003"],[19035944,"A randomised controlled trial of routine versus restrictive use of episiotomy at operative vaginal delivery: a multicentre pilot study.","BJOG",2008,"Murphy et al.",2,[9,13,17],[11.89,13.93,6.77],15.97,12,9,7,[0,0,1,0,2,1,0,2,1,2,0,0,0,1,1,0],"10.1111/j.1471-0528.2008.01960.x"],[19091393,"Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation.","Lancet",2009,"Stanley et al.",5,[4],[15.97],15.97,9,9,7,[0,2,0,0,1,1,0,0,1,1,1,0,1,0,1,0],"10.1016/S0140-6736(08)61769-9"],[19196675,"The burden of respiratory syncytial virus infection in young children.","N Engl J Med",2009,"Hall et al.",5,[2],[15.97],15.97,10,9,6,[1,0,1,2,1,0,0,0,1,1,0,0,2,0,1,0],"10.1056/NEJMoa0804877"],[19249767,"Incidence and predictors of \"late\" recurrences after endoscopic piecemeal resection of large sessile adenomas.","Gastrointest Endosc",2009,"Khashab et al.",5,[1,4],[12.65,15.97],15.97,11,9,7,[0,1,1,1,2,0,1,0,1,1,0,0,0,1,0,0],"10.1016/j.gie.2008.10.037"],[19297345,"The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal.","Ann Rheum Dis",2009,"Rudwaleit et al.",7,[11,13],[15.97,15.97],15.97,13,9,7,[1,2,1,1,2,0,2,0,1,0,3,0,0,0,0,0],"10.1136/ard.2009.108217"],[19333933,"Clinical and imaging efficacy of infliximab in HLA-B27-Positive patients with magnetic resonance imaging-determined early sacroiliitis.","Arthritis Rheum",2009,"Barkham et al.",2,[11,13],[15.97,15.97],15.97,11,9,7,[1,3,0,1,2,0,1,1,1,0,1,0,0,0,0,0],"10.1002/art.24408"],[19528344,"Medication adherence: its importance in cardiovascular outcomes.","Circulation",2009,"Ho et al.",6,[0],[13.47],15.97,15,9,9,[0,1,0,1,1,1,2,0,1,1,1,0,0,0,0,0],"10.1161/CIRCULATIONAHA.108.768986"],[19620164,"Meta-analysis: can Helicobacter pylori eradication treatment reduce the risk for gastric cancer?","Ann Intern Med",2009,"Fuccio et al.",0,[4,1,2],[11.5,9.02,9.02],15.97,10,9,7,[1,2,1,1,1,0,1,0,0,1,0,0,0,0,0,1],"10.7326/0003-4819-151-2-200907210-00009"],[19636033,"Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005).","Arch Intern Med",2009,"Nathan et al.",5,[7],[15.97],15.97,14,9,7,[3,2,1,2,1,0,1,1,0,3,0,0,0,0,0,0],"10.1001/archinternmed.2009.193"],[19766640,"Delayed-release oral mesalamine 4.8 g/day (800-mg tablet) is effective for patients with moderately active ulcerative colitis.","Gastroenterology",2009,"Sandborn et al.",2,[4],[15.97],15.97,11,9,7,[0,1,1,0,2,0,1,3,0,1,0,0,1,0,1,0],"10.1053/j.gastro.2009.08.069"],[19826022,"Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial.","JAMA",2009,"Lederle et al.",2,[0],[15.97],15.97,15,9,7,[2,1,0,2,0,1,0,1,0,0,0,1,2,1,0,0],"10.1001/jama.2009.1426"],[19996018,"Randomized comparison of strategies for type B aortic dissection: the INvestigation of STEnt Grafts in Aortic Dissection (INSTEAD) trial.","Circulation",2009,"Nienaber et al.",2,[0],[15.97],15.97,10,9,8,[0,1,1,2,1,0,0,0,0,0,0,1,1,1,0,1],"10.1161/CIRCULATIONAHA.109.886408"],[20471071,"Infection outcomes in patients with common variable immunodeficiency disorders: relationship to immunoglobulin therapy over 22 years.","J Allergy Clin Immunol",2010,"Lucas et al.",5,[2,12],[3.74,4.65],15.97,10,9,8,[1,2,0,1,1,1,0,0,1,0,0,0,0,1,0,2],"10.1016/j.jaci.2010.02.040"],[20498212,"A matrix risk model for the prediction of rapid radiographic progression in patients with rheumatoid arthritis receiving different dynamic treatment strategies: post hoc analyses from the BeSt study.","Ann Rheum Dis",2010,"Visser et al.",2,[11],[15.97],15.97,10,9,7,[1,2,1,2,1,0,1,0,0,1,0,0,0,1,0,0],"10.1136/ard.2009.121160"],[20660290,"Treatment and prognosis of mature T-cell and NK-cell lymphoma: an analysis of patients with T-cell lymphoma treated in studies of the German High-Grade Non-Hodgkin Lymphoma Study Group.","Blood",2010,"Schmitz et al.",3,[1,10],[15.97,13.47],15.97,11,9,8,[1,0,1,0,1,1,0,0,0,0,1,2,0,1,2,0],"10.1182/blood-2010-02-270785"],[21645235,"Outpatient treatment in patients with acute pulmonary embolism: the Hestia Study.","J Thromb Haemost",2011,"Zondag et al.",3,[0,3],[15.97,13.47],15.97,11,9,7,[0,1,0,1,0,0,0,1,1,1,2,1,0,0,0,2],"10.1111/j.1538-7836.2011.04388.x"],[21859995,"Oxaliplatin as adjuvant therapy for colon cancer: updated results of NSABP C-07 trial, including survival and subset analyses.","J Clin Oncol",2011,"Yothers et al.",2,[1,4],[15.97,15.97],15.97,11,9,7,[0,0,1,0,1,0,1,1,0,2,1,0,0,2,1,0],"10.1200/JCO.2011.36.4539"],[21917861,"Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors.","J Clin Endocrinol Metab",2011,"Arlt et al.",7,[1,7],[15.97,15.97],15.97,10,9,7,[0,1,0,0,0,2,1,1,1,1,0,0,2,0,1,0],"10.1210/jc.2011-1565"],[22173167,"Diagnosis of liver fibrosis and cirrhosis using liver stiffness measurement: comparison between M and XL probe of FibroScan®.","J Hepatol",2012,"de Lédinghen et al.",5,[4],[15.97],15.97,9,9,7,[0,0,1,1,1,1,2,0,0,0,1,1,0,0,1,0],"10.1016/j.jhep.2011.10.017"],[22296075,"Ulipristal acetate versus placebo for fibroid treatment before surgery.","N Engl J Med",2012,"Donnez et al.",2,[9,1],[15.97,13.27],15.97,9,9,7,[0,2,0,1,1,1,0,0,1,0,0,1,0,1,1,0],"10.1056/NEJMoa1103182"],[22370319,"Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC Intergroup Study 30987.","J Clin Oncol",2012,"Bellmunt et al.",2,[1,8],[15.97,15.97],15.97,12,9,7,[1,0,3,2,0,0,2,1,1,0,0,1,0,0,1,0],"10.1200/JCO.2011.38.6979"],[22858390,"Radial versus femoral randomized investigation in ST-segment elevation acute coronary syndrome: the RIFLE-STEACS (Radial Versus Femoral Randomized Investigation in ST-Elevation Acute Coronary Syndrome) study.","J Am Coll Cardiol",2012,"Romagnoli et al.",2,[0],[15.97],15.97,13,9,7,[0,1,0,1,0,0,2,3,0,1,0,1,1,2,0,0],"10.1016/j.jacc.2012.06.017"],[23069099,"Echocardiography integrated ACLS protocol versus conventional cardiopulmonary resuscitation in patients with pulseless electrical activity cardiac arrest.","Chin J Traumatol",2012,"Chardoli et al.",2,[0],[15.97],15.97,11,11,6,[0,0,0,1,2,1,0,0,0,1,1,0,1,0,3,1],""],[23348607,"Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: twelve-month data from a twenty-four-month phase III randomized radiographic study.","Arthritis Rheum",2013,"van der Heijde et al.",2,[11],[15.97],15.97,10,9,7,[0,0,0,1,2,1,1,1,1,0,0,0,0,1,1,0],"10.1002/art.37816"],[24332238,"Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial.","Lancet Oncol",2014,"Ford et al.",2,[1,4],[15.97,15.97],15.97,11,9,7,[0,0,0,0,2,1,0,1,1,0,0,1,0,1,2,2],"10.1016/S1470-2045(13)70549-7"],[24859362,"Rates, management, and outcome of rivaroxaban bleeding in daily care: results from the Dresden NOAC registry.","Blood",2014,"Beyer-Westendorf et al.",3,[0],[13.47],15.97,15,9,7,[0,0,0,0,1,2,1,4,1,1,0,0,0,1,1,0],"10.1182/blood-2014-03-563577"],[26091833,"Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa-pT1 Urothelial Carcinoma of the Bladder: Which Patients Benefit from the Instillation?","Eur Urol",2016,"Sylvester et al.",0,[1,8],[15.97,15.97],15.97,13,9,8,[0,0,0,0,0,1,0,3,1,2,0,2,0,2,1,1],"10.1016/j.eururo.2015.05.050"],[3593964,"Development of the human coagulation system in the full-term infant.","Blood",1987,"Andrew et al.",7,[0,10],[8.47,4.65],15.95,10,9,8,[1,2,3,2,0,0,0,0,0,1,0,0,0,0,1,0],""],[7564670,"Early administration of terlipressin plus glyceryl trinitrate to control active upper gastrointestinal bleeding in cirrhotic patients.","Lancet",1995,"Levacher et al.",2,[4],[15.95],15.95,9,9,8,[0,1,1,0,0,0,0,1,1,0,2,0,0,0,3,0],"10.1016/s0140-6736(95)92708-5"],[8174982,"Acute gastrointestinal haemorrhage in anticoagulated patients: diagnoses and response to endoscopic treatment.","Gut",1994,"Choudari et al.",5,[4],[15.95],15.95,10,9,8,[0,0,0,1,1,3,0,1,1,0,2,0,0,0,0,0],"10.1136/gut.35.4.464"],[8942775,"Randomised controlled trial of faecal-occult-blood screening for colorectal cancer.","Lancet",1996,"Hardcastle et al.",2,[1,4],[15.95,15.95],15.95,12,9,8,[0,4,3,0,1,1,1,0,0,0,1,0,0,0,0,0],"10.1016/S0140-6736(96)03386-7"],[9558287,"\"Salvage\" transjugular intrahepatic portosystemic shunts: gastric fundal compared with esophageal variceal bleeding.","Gastroenterology",1998,"Chau et al.",7,[4],[15.95],15.95,9,9,8,[0,1,1,0,0,0,2,1,2,2,0,0,0,0,0,0],"10.1016/s0016-5085(98)00640-4"],[9690404,"Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomised controlled trials. 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al.",3,[5,13],[15.95,14.44],15.95,9,9,8,[0,3,1,0,0,1,0,0,1,0,0,0,2,1,0,0],"10.1016/s0140-6736(00)04561-x"],[11440947,"Systematic reviews in health care: Assessing the quality of controlled clinical trials.","BMJ",2001,"Jüni et al.",6,[0],[1.0],15.95,9,9,8,[3,2,1,1,0,1,0,0,0,1,0,0,0,0,0,0],"10.1136/bmj.323.7303.42"],[11849464,"Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes.","Kidney Int",2002,"Schrier et al.",2,[0,7,8],[5.29,6.2,6.77],15.95,11,9,8,[0,0,3,1,2,0,0,0,1,1,1,0,0,0,0,0],"10.1046/j.1523-1755.2002.00213.x"],[11868001,"Procedural success and complications of large-scale screening colonoscopy.","Gastrointest Endosc",2002,"Nelson et al.",7,[1,4],[15.95,15.95],15.95,10,9,8,[1,3,0,1,0,2,0,0,0,1,0,1,0,0,0,0],"10.1067/mge.2002.121883"],[11937179,"Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.","Lancet",2002,"Lindholm et al.",2,[0,7],[12.24,11.04],15.95,14,8,7,[1,1,2,2,1,1,0,0,1,0,2,0,1,1,0,0],"10.1016/S0140-6736(02)08090-X"],[12297842,"Terlipressin therapy with and without albumin for patients with hepatorenal syndrome: results of a prospective, nonrandomized study.","Hepatology",2002,"Ortega et al.",3,[4,8],[15.95,4.65],15.95,9,9,8,[0,1,1,0,0,1,0,3,0,0,1,0,0,2,0,0],"10.1053/jhep.2002.35819"],[12578508,"Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study.","Arch Intern Med",2003,"Fasano et al.",7,[4,7],[15.95,13.27],15.95,10,9,8,[0,1,3,1,0,0,2,2,0,0,0,0,0,0,1,0],"10.1001/archinte.163.3.286"],[14581387,"Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention.","Circulation",2003,"Sarnak et al.",6,[0,8],[8.47,4.65],15.95,22,11,11,[2,4,3,0,1,0,0,1,0,0,0,0,1,0,0,0],"10.1161/01.CIR.0000095676.90936.80"],[15082703,"Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit.","JAMA",2004,"Ely et al.",5,[5,6],[9.17,9.17],15.95,9,9,8,[0,0,3,0,2,0,0,1,0,1,0,1,0,1,0,0],"10.1001/jama.291.14.1753"],[15277423,"Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study.","Diabetes Care",2004,"Wackers et al.",2,[0,7],[13.46,11.65],15.95,13,8,7,[3,2,1,1,1,1,0,1,1,1,0,0,0,0,0,1],"10.2337/diacare.27.8.1954"],[15362027,"Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial.","Gastroenterology",2004,"Hanauer et al.",2,[4],[15.95],15.95,9,9,8,[1,0,2,2,0,0,2,1,0,0,0,0,0,1,0,0],"10.1053/j.gastro.2004.06.002"],[15368452,"Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates.","Hepatology",2004,"Glantz et al.",5,[9,4,17],[11.58,11.85,0.0],15.95,10,9,8,[0,0,0,0,0,0,0,0,1,1,2,0,3,1,1,0],"10.1002/hep.20336"],[15591511,"PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis.","Gut",2005,"Loftus et al.",5,[4],[15.95],15.95,9,9,8,[0,1,0,0,0,0,2,1,1,0,0,0,0,0,3,1],"10.1136/gut.2004.046615"],[16043987,"Use of endoscopic ultrasound to guide combination medical and surgical therapy for patients with Crohn's perianal fistulas.","Inflamm Bowel Dis",2005,"Schwartz et al.",5,[4],[15.95],15.95,10,9,8,[0,0,1,2,3,0,0,1,0,0,0,0,0,0,2,1],"10.1097/01.mib.0000172811.57242.18"],[16044444,"Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004.","Am J Hematol",2005,"Gertz et al.",4,[7],[8.39],15.95,9,9,8,[0,1,0,0,2,1,0,0,0,0,0,0,2,1,0,2],"10.1002/ajh.20381"],[16530532,"American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease.","Gastroenterology",2006,"Lichtenstein et al.",6,[4],[15.95],15.95,9,9,8,[1,2,0,0,1,0,2,1,2,0,0,0,0,0,0,0],"10.1053/j.gastro.2006.01.048"],[16539636,"Characteristics associated with liver graft failure: the concept of a donor risk index.","Am J Transplant",2006,"Feng et al.",7,[4],[8.47],15.95,10,9,9,[0,1,0,1,0,1,0,1,0,0,3,0,0,2,0,0],"10.1111/j.1600-6143.2006.01242.x"],[16546624,"Second symposium on the definition and management of anaphylaxis: summary report--second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.","Ann Emerg Med",2006,"Sampson et al.",7,[12,1],[10.16,6.16],15.95,10,9,8,[2,2,1,1,0,0,3,0,0,0,0,0,0,0,0,1],"10.1016/j.annemergmed.2006.01.018"],[17253451,"Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis.","Cochrane Database Syst Rev",2007,"Timmer et al.",0,[4],[15.95],15.95,9,9,8,[2,3,1,0,1,0,1,0,0,0,0,0,0,0,1,0],"10.1002/14651858.CD000478.pub2"],[17374834,"Randomized controlled trial of resection versus radiotherapy after induction chemotherapy in stage IIIA-N2 non-small-cell lung cancer.","J Natl Cancer Inst",2007,"van Meerbeeck et al.",2,[1,3],[15.95,15.95],15.95,10,9,8,[0,0,4,0,2,0,1,0,0,1,0,1,1,0,0,0],"10.1093/jnci/djk093"],[17384437,"Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial.","JAMA",2007,"Konstam et al.",2,[0],[11.58],15.95,11,9,9,[0,0,2,2,0,1,2,1,1,0,0,0,0,0,0,0],"10.1001/jama.297.12.1319"],[17403800,"Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.","J Bone Joint Surg Am",2007,"Kurtz et al.",7,[2],[5.29],15.95,12,9,8,[0,0,0,0,1,0,4,0,0,0,1,0,1,1,1,0],"10.2106/JBJS.F.00222"],[17513817,"Imaging in local staging of gastric cancer: a systematic review.","J Clin Oncol",2007,"Kwee et al.",1,[1],[15.17],15.95,10,9,8,[1,2,1,0,0,1,0,0,0,0,0,2,0,0,0,3],"10.1200/JCO.2006.09.5224"],[17702958,"Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan.","Stroke",2007,"Ogawa et al.",2,[0,5],[15.95,15.95],15.95,11,9,8,[0,2,3,0,0,0,0,1,2,1,1,0,0,0,0,0],"10.1161/STROKEAHA.107.488551"],[17986697,"Prevalence of chronic kidney disease in the United States.","JAMA",2007,"Coresh et al.",5,[8],[11.58],15.95,10,9,8,[1,0,0,0,0,0,2,2,0,0,2,1,0,0,1,0],"10.1001/jama.298.17.2038"],[18358926,"Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial.","Lancet",2008,"Smolen et al.",2,[11],[15.95],15.95,9,9,8,[3,1,2,0,0,0,1,0,1,0,1,0,0,0,0,0],"10.1016/S0140-6736(08)60453-5"],[18486740,"Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2).","Lancet",2008,"Papp et al.",2,[14],[15.95],15.95,10,9,9,[0,1,1,0,0,1,0,0,4,1,0,1,0,0,0,0],"10.1016/S0140-6736(08)60726-6"],[18848905,"Cost effectiveness of alternative surveillance strategies for hepatocellular carcinoma in patients with cirrhosis.","Clin Gastroenterol Hepatol",2008,"Andersson et al.",7,[4,1],[15.95,12.24],15.95,13,8,9,[0,1,0,0,1,1,0,0,1,1,0,1,1,1,1,1],"10.1016/j.cgh.2008.08.005"],[18848939,"Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease.","Gastroenterology",2009,"Lok et al.",7,[4,1,2],[15.95,10.26,7.22],15.95,11,9,8,[2,2,0,2,0,2,1,0,0,0,0,1,0,0,0,0],"10.1053/j.gastro.2008.09.014"],[19077726,"Follow-up of pregnant women with autoimmune hepatitis: the disease behavior along with maternal and fetal outcomes.","J Clin Gastroenterol",2009,"Terrabuio et al.",7,[4,9],[12.16,2.0],15.95,9,9,8,[0,0,0,0,2,2,1,0,0,1,1,0,2,0,0,0],"10.1097/MCG.0b013e318176b8c5"],[19095376,"Postoperative external beam radiotherapy for differentiated thyroid cancer: outcomes and morbidity with conformal treatment.","Int J Radiat Oncol Biol Phys",2009,"Schwartz et al.",5,[1,7],[14.06,15.95],15.95,10,9,8,[0,1,0,1,0,2,0,0,1,2,0,0,0,0,3,0],"10.1016/j.ijrobp.2008.09.023"],[19211471,"Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis.","JAMA",2009,"Stothard et al.",0,[7,9,17],[10.83,15.95,2.69],15.95,10,9,8,[0,1,0,0,2,0,1,1,4,0,1,0,0,0,0,0],"10.1001/jama.2009.113"],[19318632,"Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation.","J Natl Cancer Inst",2009,"Pointreau et al.",2,[1,16,3],[15.95,7.47,3.74],15.95,10,9,8,[3,0,1,0,0,0,0,1,0,0,0,1,0,1,3,0],"10.1093/jnci/djp007"],[19364995,"A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.","Arch Intern Med",2009,"Mente et al.",1,[0],[10.26],15.95,15,9,8,[3,0,1,0,2,1,0,1,2,0,0,0,0,0,0,0],"10.1001/archinternmed.2009.38"],[19487380,"Outcome of primary tumor in patients with synchronous stage IV colorectal cancer receiving combination chemotherapy without surgery as initial treatment.","J Clin Oncol",2009,"Poultsides et al.",5,[1,4],[15.95,15.95],15.95,9,9,8,[3,2,1,0,1,0,0,0,1,1,0,0,0,0,0,0],"10.1200/JCO.2008.20.9817"],[19608028,"Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device.","J Am Coll Cardiol",2009,"Pagani et al.",3,[0],[15.95],15.95,12,9,8,[0,3,2,0,1,1,0,0,1,1,0,0,0,0,0,0],"10.1016/j.jacc.2009.03.055"],[19687335,"Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract.","J Clin Oncol",2009,"Bellmunt et al.",2,[1,8],[15.95,15.95],15.95,16,8,7,[3,2,0,2,0,1,2,1,1,0,1,2,0,0,1,0],"10.1200/JCO.2008.20.5534"],[19733260,"Clinical, endoscopic, and histologic findings distinguish eosinophilic esophagitis from gastroesophageal reflux disease.","Clin Gastroenterol Hepatol",2009,"Dellon et al.",5,[4],[15.95],15.95,9,9,8,[0,0,1,1,0,0,0,1,0,0,0,0,0,2,3,1],"10.1016/j.cgh.2009.08.030"],[19833379,"Bolus tenecteplase for right ventricle dysfunction in hemodynamically stable patients with pulmonary embolism.","Thromb Res",2010,"Becattini et al.",2,[0,3],[15.95,13.38],15.95,10,9,8,[2,1,0,1,0,0,0,0,1,3,2,0,0,0,0,0],"10.1016/j.thromres.2009.09.017"],[20071648,"Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease.","Am J Clin Nutr",2010,"Siri-Tarino et al.",0,[0,5],[12.63,2.69],15.95,13,9,10,[0,1,2,0,1,0,0,3,0,0,1,0,1,0,0,0],"10.3945/ajcn.2009.27725"],[20109213,"Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial.","Respir Res",2010,"Sethi et al.",2,[3],[15.95],15.95,11,9,9,[1,1,2,0,1,1,3,0,0,0,0,0,0,0,0,0],"10.1186/1465-9921-11-10"],[20141809,"AGA technical review on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease.","Gastroenterology",2010,"Farraye et al.",6,[4,1],[15.95,6.2],15.95,11,9,10,[0,0,2,1,4,0,0,1,0,0,1,0,0,0,1,0],"10.1053/j.gastro.2009.12.035"],[20188410,"Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis.","Lancet",2010,"Todo et al.",7,[1,9],[15.95,15.95],15.95,9,9,8,[0,0,1,2,0,0,3,0,0,1,0,1,1,0,0,0],"10.1016/S0140-6736(09)62002-X"],[20577000,"Liver dysfunction related to hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive therapy.","Gut",2010,"Loras et al.",7,[4,2],[15.95,2.0],15.95,10,9,8,[0,0,2,0,0,0,2,1,0,0,2,1,0,0,2,0],"10.1136/gut.2010.208413"],[20646177,"Puberty suppression in adolescents with gender identity disorder: a prospective follow-up study.","J Sex Med",2011,"de Vries et al.",5,[6],[2.0],15.95,9,9,8,[0,1,0,2,1,0,3,0,0,0,0,0,0,1,0,1],"10.1111/j.1743-6109.2010.01943.x"],[20688887,"A systematic review and meta-analysis of pregnancy outcomes in patients with systemic lupus erythematosus and lupus nephritis.","Clin J Am Soc Nephrol",2010,"Smyth et al.",0,[11,8,9],[11.58,8.47,6.77],15.95,11,9,8,[0,2,0,0,2,0,1,0,2,2,1,0,0,0,0,0],"10.2215/CJN.00240110"],[21319193,"Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using liver stiffness measurement (FibroScan).","Hepatology",2011,"Jung et al.",5,[4,1,2],[15.95,5.29,2.69],15.95,10,9,8,[0,1,1,0,2,2,0,0,0,0,0,0,0,2,1,0],"10.1002/hep.24121"],[21417952,"Dalteparin versus unfractionated heparin in critically ill patients.","N Engl J Med",2011,"Cook et al.",2,[0],[12.63],15.95,13,9,10,[1,2,2,0,0,0,1,2,0,3,0,0,0,0,0,0],"10.1056/NEJMoa1014475"],[21439633,"The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.","Lancet",2011,"Roberts et al.",2,[13],[10.83],15.95,9,9,8,[0,0,1,0,3,0,1,0,0,0,1,0,0,1,2,0],"10.1016/S0140-6736(11)60278-X"],[21439754,"Impact of coronary artery calcium scanning on coronary risk factors and downstream testing the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) prospective randomized trial.","J Am Coll Cardiol",2011,"Rozanski et al.",2,[0,7],[15.95,12.63],15.95,12,9,9,[0,0,0,0,1,0,3,1,1,0,2,1,0,0,0,0],"10.1016/j.jacc.2011.01.019"],[21741922,"A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome.","Gastroenterology",2011,"van Santvoort et al.",5,[4],[15.95],15.95,10,9,8,[0,0,2,0,1,2,1,0,0,0,1,0,0,3,0,0],"10.1053/j.gastro.2011.06.073"],[21903060,"Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance.","J Am Coll Cardiol",2011,"Eckart et al.",5,[0],[15.95],15.95,18,10,6,[0,0,0,1,1,1,2,1,1,1,2,0,1,1,0,0],"10.1016/j.jacc.2011.01.049"],[22070475,"Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis.","N Engl J Med",2011,"Nguyen-Khac et al.",2,[4],[15.95],15.95,9,9,8,[0,1,1,0,0,0,0,1,1,3,0,0,0,2,0,0],"10.1056/NEJMoa1101214"],[22070538,"Applicability and results of Maastricht type 2 donation after cardiac death liver transplantation.","Am J Transplant",2012,"Fondevila et al.",7,[0],[5.94],15.95,9,9,8,[0,0,0,1,3,0,1,0,0,0,1,0,0,1,2,0],"10.1111/j.1600-6143.2011.03834.x"],[22115901,"Intensive glycaemic control for patients with type 2 diabetes: systematic review with meta-analysis and trial sequential analysis of randomised clinical trials.","BMJ",2011,"Hemmingsen et al.",0,[0,7],[12.16,10.83],15.95,12,9,8,[0,0,4,1,0,0,0,2,1,0,1,0,0,1,0,0],"10.1136/bmj.d6898"],[22291074,"Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study.","J Clin Oncol",2012,"Walker et al.",2,[1,9],[15.95,15.95],15.95,10,9,8,[0,0,0,2,0,0,2,0,1,0,1,1,2,0,0,0],"10.1200/JCO.2011.38.8645"],[22926176,"Diagnosis and management of childhood obstructive sleep apnea syndrome.","Pediatrics",2012,"Marcus et al.",6,[3,5],[14.06,13.27],15.95,9,9,8,[0,0,0,0,0,0,3,1,1,0,2,0,1,1,0,0],"10.1542/peds.2012-1672"],[23353641,"Association between reduced levels of alkaline phosphatase and survival times of patients with primary sclerosing cholangitis.","Clin Gastroenterol Hepatol",2013,"Lindström et al.",2,[4],[15.95],15.95,9,9,8,[0,0,0,0,2,0,1,1,1,0,0,2,0,2,0,0],"10.1016/j.cgh.2012.12.032"],[23408728,"A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II).","Obesity (Silver Spring)",2013,"Apovian et al.",2,[7,0],[14.06,2.69],15.95,10,9,8,[0,0,0,0,1,1,0,2,0,0,0,2,1,0,0,2],"10.1002/oby.20309"],[23476049,"A specific antidote for dabigatran: functional and structural characterization.","Blood",2013,"Schiele et al.",7,[0,5],[13.38,6.77],15.95,9,9,8,[0,0,0,0,1,3,0,2,0,0,0,1,0,1,1,0],"10.1182/blood-2012-11-468207"],[23728637,"Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease.","Cochrane Database Syst Rev",2013,"Sigterman et al.",0,[4],[15.95],15.95,9,9,8,[0,0,0,0,0,2,1,1,0,0,0,3,1,0,1,0],"10.1002/14651858.CD002095.pub5"],[23782157,"Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma.","N Engl J Med",2013,"Wang et al.",3,[1,10],[15.95,15.95],15.95,10,9,8,[0,0,0,2,0,0,4,1,0,0,1,1,0,1,0,0],"10.1056/NEJMoa1306220"],[23954343,"Benefits of statins in elderly subjects without established cardiovascular disease: a meta-analysis.","J Am Coll Cardiol",2013,"Savarese et al.",0,[0],[13.38],15.95,15,9,10,[0,0,0,0,1,2,0,2,1,0,0,0,0,2,0,1],"10.1016/j.jacc.2013.07.069"],[23979955,"The effect of three or six years of denosumab exposure in women with postmenopausal osteoporosis: results from the FREEDOM extension.","J Clin Endocrinol Metab",2013,"Bone et al.",2,[13,7],[15.95,14.06],15.95,10,9,8,[0,0,0,2,0,1,2,0,1,3,0,0,0,0,0,1],"10.1210/jc.2013-1597"],[24071617,"Incidence, predictors, and outcome of difficult mask ventilation combined with difficult laryngoscopy: a report from the multicenter perioperative outcomes group.","Anesthesiology",2013,"Kheterpal et al.",7,[3],[14.06],15.95,11,9,8,[0,0,0,1,1,1,0,3,0,3,0,1,0,0,0,0],"10.1097/ALN.0000435832.39353.20"],[24145677,"Clinical and endoscopic characteristics do not reliably differentiate PPI-responsive esophageal eosinophilia and eosinophilic esophagitis in patients undergoing upper endoscopy: a prospective cohort study.","Am J Gastroenterol",2013,"Dellon et al.",5,[4,10,12],[15.95,15.95,15.95],15.95,9,9,8,[0,0,0,0,0,1,0,1,0,1,0,0,0,4,1,1],"10.1038/ajg.2013.363"],[24399231,"Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis.","Ann Rheum Dis",2014,"Nam et al.",0,[11],[15.95],15.95,9,9,8,[0,0,0,2,1,0,3,1,1,0,0,0,0,1,0,0],"10.1136/annrheumdis-2013-204577"],[24450857,"Idelalisib and rituximab in relapsed chronic lymphocytic leukemia.","N Engl J Med",2014,"Furman et al.",2,[1,10],[15.95,15.95],15.95,10,9,8,[0,0,0,0,2,0,2,2,0,0,1,1,0,0,2,0],"10.1056/NEJMoa1315226"],[24559784,"EUS-FNA is superior to ERCP-based tissue sampling in suspected malignant biliary obstruction: results of a prospective, single-blind, comparative study.","Gastrointest Endosc",2014,"Weilert et al.",3,[4,1,7],[15.95,15.17,2.69],15.95,10,9,8,[0,0,0,0,0,1,1,0,0,0,1,0,3,1,2,0],"10.1016/j.gie.2013.12.031"],[24650881,"Surgical ablation for treatment of atrial fibrillation in cardiac surgery: a cumulative meta-analysis of randomised controlled trials.","Heart",2014,"Phan et al.",0,[0],[15.95],15.95,15,9,8,[0,1,0,0,0,1,0,1,1,1,0,0,0,5,0,0],"10.1136/heartjnl-2013-305351"],[24785860,"Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging workshop.","Obstet Gynecol",2014,"Reddy et al.",7,[9,17],[12.32,5.78],15.95,12,11,8,[0,0,0,0,0,3,2,2,0,2,1,0,1,0,0,0],"10.1097/AOG.0000000000000245"],[24928290,"Vertical transmission of hepatitis C virus: systematic review and meta-analysis.","Clin Infect Dis",2014,"Benova et al.",0,[4,2],[14.06,8.47],15.95,10,9,9,[0,0,0,0,0,0,0,0,1,2,2,0,1,0,2,1],"10.1093/cid/ciu447"],[25175921,"Prehospital ticagrelor in ST-segment elevation myocardial infarction.","N Engl J Med",2014,"Montalescot et al.",2,[0],[15.95],15.95,16,10,6,[0,0,0,1,2,0,1,2,1,2,0,1,1,1,1,0],"10.1056/NEJMoa1407024"],[25337750,"Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer.","N Engl J Med",2014,"Loupakis et al.",2,[1,4],[15.95,14.06],15.95,11,9,8,[0,0,0,0,0,0,0,3,1,2,2,0,1,0,2,0],"10.1056/NEJMoa1403108"],[25599350,"Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis.","Ann Intern Med",2015,"Biswas et al.",0,[0,7,1],[7.47,7.75,1.0],15.95,10,9,8,[0,0,0,0,0,0,0,1,2,3,0,2,0,1,0,1],"10.7326/M14-1651"],[25878028,"Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials.","Lancet Respir Med",2015,"Pascoe et al.",2,[3],[15.95],15.95,9,9,8,[0,0,0,0,0,1,3,1,1,0,2,0,0,0,0,1],"10.1016/S2213-2600(15)00106-X"],[26084406,"The empirical antibiotic treatment of nosocomial spontaneous bacterial peritonitis: Results of a randomized, controlled clinical trial.","Hepatology",2016,"Piano et al.",2,[2,4],[1.0,15.95],15.95,9,9,8,[0,0,0,0,0,0,1,2,1,0,3,0,0,1,1,0],"10.1002/hep.27941"],[26172895,"Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial.","JAMA",2015,"Bakris et al.",2,[7,8],[13.27,9.77],15.95,10,9,8,[0,0,0,0,0,0,0,1,1,1,0,2,0,3,2,0],"10.1001/jama.2015.7446"],[26193126,"A Trial of Early Antiretrovirals and Isoniazid Preventive Therapy in Africa.","N Engl J Med",2015,"Danel et al.",2,[2,12,9],[10.86,8.39,8.39],15.95,9,9,8,[0,0,0,0,1,1,0,0,4,1,1,0,1,0,0,0],"10.1056/NEJMoa1507198"],[26325537,"High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial.","J Hepatol",2016,"Larsen et al.",2,[4],[13.38],15.95,11,9,8,[0,0,0,0,0,0,0,0,2,0,0,1,2,4,1,1],"10.1016/j.jhep.2015.08.018"],[26651115,"Comparing Mechanical Bowel Preparation With Both Oral and Systemic Antibiotics Versus Mechanical Bowel Preparation and Systemic Antibiotics Alone for the Prevention of Surgical Site Infection After Elective Colorectal Surgery: A Meta-Analysis of Randomized Controlled Clinical Trials.","Dis Colon Rectum",2016,"Chen et al.",7,[1,4],[9.77,6.77],15.95,9,9,8,[0,0,0,0,0,0,2,1,2,2,0,0,1,1,0,0],"10.1097/DCR.0000000000000524"],[26756588,"Effectiveness of Breast Cancer Screening: Systematic Review and Meta-analysis to Update the 2009 U.S. Preventive Services Task Force Recommendation.","Ann Intern Med",2016,"Nelson et al.",0,[1],[15.95],15.95,9,9,8,[0,0,0,0,0,1,0,2,2,0,1,0,0,2,1,0],"10.7326/M15-0969"],[26878173,"Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers.","J Clin Invest",2016,"Landa et al.",7,[1,7],[13.38,15.95],15.95,9,9,8,[0,0,0,0,0,0,0,0,1,1,1,0,0,1,4,1],"10.1172/JCI85271"],[26988871,"Periprocedural management of patients receiving a vitamin K antagonist or a direct oral anticoagulant requiring an elective procedure or surgery.","J Thromb Haemost",2016,"Spyropoulos et al.",6,[0],[15.95],15.95,10,9,9,[0,0,0,0,0,0,0,0,2,1,2,1,1,0,0,2],"10.1111/jth.13305"],[27144625,"Functional Esophageal Disorders.","Gastroenterology",2016,"Aziz et al.",7,[4],[15.95],15.95,9,9,8,[0,0,0,0,0,0,0,1,0,1,1,1,0,0,3,2],"10.1053/j.gastro.2016.02.012"],[27302126,"Fresh frozen plasma versus prothrombin complex concentrate in patients with intracranial haemorrhage related to vitamin K antagonists (INCH): a randomised trial.","Lancet Neurol",2016,"Steiner et al.",2,[0,5],[10.16,7.47],15.95,9,9,8,[0,0,0,0,0,0,0,1,0,0,1,2,2,1,2,0],"10.1016/S1474-4422(16)00110-1"],[27540850,"Incidence of Programmed Cell Death 1 Inhibitor-Related Pneumonitis in Patients With Advanced Cancer: A Systematic Review and Meta-analysis.","JAMA Oncol",2016,"Nishino et al.",0,[1,3,2],[14.06,6.77,0.0],15.95,9,9,8,[0,0,0,0,0,0,1,1,1,1,2,3,0,0,0,0],"10.1001/jamaoncol.2016.2453"],[27604504,"Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial.","Lancet",2016,"Mulvenna et al.",2,[1,5,3],[15.95,7.47,3.1],15.95,10,9,9,[0,0,0,0,0,0,0,1,1,1,2,3,0,0,2,0],"10.1016/S0140-6736(16)30825-X"],[27686946,"Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.","Lancet Oncol",2016,"Baumert et al.",2,[1,5],[15.95,15.95],15.95,9,9,8,[0,0,0,0,0,0,2,1,0,0,0,2,0,1,2,1],"10.1016/S1470-2045(16)30313-8"],[27816756,"Sarcopenia Is Risk Factor for Development of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt Placement.","Clin Gastroenterol Hepatol",2017,"Nardelli et al.",5,[4,5,7],[15.95,1.0,1.0],15.95,9,9,8,[0,0,0,0,0,0,0,0,1,2,2,0,0,2,1,1],"10.1016/j.cgh.2016.10.028"],[28159465,"A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study.","Lancet Oncol",2017,"Rossi et al.",5,[1,9],[15.95,15.95],15.95,10,9,8,[0,0,0,0,0,0,0,0,0,1,1,2,3,0,1,1],"10.1016/S1470-2045(17)30068-2"],[28512034,"Diagnostic yield of capsule endoscopy versus magnetic resonance enterography and small bowel contrast ultrasound in the evaluation of small bowel Crohn's disease: Systematic review and meta-analysis.","Dig Liver Dis",2017,"Kopylov et al.",0,[4],[15.95],15.95,9,9,8,[0,0,0,0,0,0,0,0,1,1,2,0,1,1,3,0],"10.1016/j.dld.2017.04.013"],[28645736,"Liver transplantation in the most severely ill cirrhotic patients: A multicenter study in acute-on-chronic liver failure grade 3.","J Hepatol",2017,"Artru et al.",5,[4],[15.95],15.95,11,11,7,[0,0,0,0,0,0,0,1,0,2,0,1,2,4,1,0],"10.1016/j.jhep.2017.06.009"],[28841387,"Efficacy and Safety Outcomes in Patients With Advanced Melanoma Who Discontinued Treatment With Nivolumab and Ipilimumab Because of Adverse Events: A Pooled Analysis of Randomized Phase II and III Trials.","J Clin Oncol",2017,"Schadendorf et al.",5,[1,14],[15.95,4.65],15.95,10,9,8,[0,0,0,0,0,0,0,2,3,1,1,0,2,0,1,0],"10.1200/JCO.2017.73.2289"],[29803839,"Risk of Neoplastic Progression in Individuals at High Risk for Pancreatic Cancer Undergoing Long-term Surveillance.","Gastroenterology",2018,"Canto et al.",5,[1,4,7],[15.95,15.95,14.06],15.95,9,9,8,[0,0,0,0,0,0,0,0,1,0,1,3,0,1,1,2],"10.1053/j.gastro.2018.05.035"],[29899139,"Hypertensive Disorders of Pregnancy: ISSHP Classification, Diagnosis, and Management Recommendations for International Practice.","Hypertension",2018,"Brown et al.",6,[0,9],[6.2,6.77],15.95,9,9,8,[0,0,0,0,0,0,0,0,1,2,0,1,1,3,1,0],"10.1161/HYPERTENSIONAHA.117.10803"],[30578325,"Room Air for Initiating Term Newborn Resuscitation: A Systematic Review With Meta-analysis.","Pediatrics",2019,"Welsford et al.",0,[9],[2.69],15.95,9,9,8,[0,0,0,0,0,0,0,0,1,1,1,0,0,1,4,1],"10.1542/peds.2018-1825"],[30660725,"Noninvasive Assessment of Liver Disease in Patients With Nonalcoholic Fatty Liver Disease.","Gastroenterology",2019,"Castera et al.",6,[4],[14.06],15.95,14,9,11,[0,0,0,0,0,0,0,0,0,2,2,2,2,2,1,0],"10.1053/j.gastro.2018.12.036"],[30703272,"Exercise for preventing falls in older people living in the community.","Cochrane Database Syst Rev",2019,"Sherrington et al.",0,[13],[14.06],15.95,10,9,8,[0,0,0,0,0,0,0,0,0,0,2,1,2,1,3,1],"10.1002/14651858.CD012424.pub2"],[31216398,"Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease.","N Engl J Med",2019,"Nagel et al.",2,[0],[15.95],15.95,11,9,9,[0,0,0,0,0,0,0,0,0,1,1,4,1,1,1,0],"10.1056/NEJMoa1716734"],[31553834,"Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis.","N Engl J Med",2019,"Sands et al.",2,[4],[15.95],15.95,11,9,9,[0,0,0,0,0,0,0,0,0,1,1,2,2,3,2,0],"10.1056/NEJMoa1905725"],[14978666,"The effect of tumor necrosis factor blockade on the response to pneumococcal vaccination in patients with rheumatoid arthritis and ankylosing spondylitis.","Semin Arthritis Rheum",2004,"Elkayam et al.",5,[11,13],[14.25,0.0],15.94,11,10,9,[5,1,0,0,2,2,0,0,0,0,0,0,0,0,0,0],"10.1053/j.semarthrit.2003.10.003"],[20218876,"Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).","Clin Infect Dis",2010,"Pappas et al.",5,[2],[13.04],15.94,10,10,9,[3,0,0,0,0,3,0,0,1,0,0,0,0,0,3,0],"10.1086/651262"],[28973220,"Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery: A Randomized Clinical Trial.","JAMA",2017,"Futier et al.",2,[0],[14.25],15.94,11,10,9,[0,0,0,0,0,0,0,0,0,0,0,0,2,4,1,3],"10.1001/jama.2017.14172"],[32738937,"Dementia prevention, intervention, and care: 2020 report of the Lancet Commission.","Lancet",2020,"Livingston et al.",6,[5,6],[9.17,9.17],15.94,11,10,9,[0,0,0,0,0,0,0,0,0,0,0,1,1,4,4,0],"10.1016/S0140-6736(20)30367-6"],[33373111,"Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0©.","Neurogastroenterol Motil",2021,"Yadlapati et al.",6,[4],[14.25],15.94,10,10,9,[0,0,0,0,0,0,0,0,0,0,1,0,0,3,3,3],"10.1111/nmo.14058"],[34010531,"Final Report of a Trial of Intensive versus Standard Blood-Pressure Control.","N Engl J Med",2021,"Lewis et al.",2,[0],[14.25],15.94,16,10,10,[0,0,0,0,0,0,0,0,0,0,0,1,0,4,5,1],"10.1056/NEJMoa1901281"],[34237250,"Cabozantinib for radioiodine-refractory differentiated thyroid cancer (COSMIC-311): a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet Oncol",2021,"Brose et al.",2,[1,7],[15.94,14.25],15.94,10,10,9,[0,0,0,0,0,0,0,0,0,0,0,1,0,1,7,1],"10.1016/S1470-2045(21)00332-6"],[2863541,"Need for long-term anticoagulant treatment in symptomatic calf-vein thrombosis.","Lancet",1985,"Lagerstedt et al.",2,[0,11],[15.93,0.0],15.93,10,10,8,[2,2,2,0,0,0,0,1,0,0,3,0,0,0,0,0],"10.1016/s0140-6736(85)90459-3"],[11006365,"Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group.","N Engl J Med",2000,"Jacobs et al.",2,[5],[15.93],15.93,10,10,8,[1,2,4,2,0,0,0,1,0,0,0,0,0,0,0,0],"10.1056/NEJM200009283431301"],[25980660,"High-Flow Nasal Oxygen vs Noninvasive Positive Airway Pressure in Hypoxemic Patients After Cardiothoracic Surgery: A Randomized Clinical Trial.","JAMA",2015,"Stéphan et al.",2,[3],[15.93],15.93,11,10,8,[0,0,0,0,0,0,1,0,0,3,3,2,0,1,0,0],"10.1001/jama.2015.5213"],[26436963,"Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves.","N Engl J Med",2015,"Makkar et al.",2,[0],[15.19],15.93,17,10,9,[0,0,0,0,0,0,4,2,2,0,2,0,1,0,0,0],"10.1056/NEJMoa1509233"],[26569658,"Sofosbuvir and Velpatasvir for HCV in Patients with Decompensated Cirrhosis.","N Engl J Med",2015,"Curry et al.",2,[4,2],[15.93,12.55],15.93,11,10,8,[0,0,0,0,0,0,3,5,0,1,0,1,0,1,0,0],"10.1056/NEJMoa1512614"],[27144631,"Childhood Functional Gastrointestinal Disorders: Neonate/Toddler.","Gastroenterology",2016,"Benninga et al.",7,[4],[8.47],15.93,10,10,8,[0,0,0,0,0,0,0,0,0,2,0,0,1,3,2,2],"10.1053/j.gastro.2016.02.016"],[28448662,"Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer: The AIO-FLOT3 Trial.","JAMA Oncol",2017,"Al-Batran et al.",3,[1,4,3],[15.93,15.93,0.0],15.93,10,10,8,[0,0,0,0,0,0,0,1,0,0,0,1,0,4,2,2],"10.1001/jamaoncol.2017.0515"],[29050854,"Pretransplantation Portal Vein Recanalization and Transjugular Intrahepatic Portosystemic Shunt Creation for Chronic Portal Vein Thrombosis: Final Analysis of a 61-Patient Cohort.","J Vasc Interv Radiol",2017,"Thornburg et al.",5,[0],[3.25],15.93,10,10,8,[0,0,0,0,0,0,0,0,1,1,3,0,0,3,2,0],"10.1016/j.jvir.2017.08.005"],[29499873,"Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.","Lancet",2018,"McManus et al.",2,[0],[14.13],15.93,12,10,8,[0,0,0,0,0,0,0,0,3,1,1,0,0,4,1,0],"10.1016/S0140-6736(18)30309-X"],[31008867,"Thromboelastography-guided Blood Product Transfusion in Cirrhosis Patients With Variceal Bleeding: A Randomized Controlled Trial.","J Clin Gastroenterol",2020,"Rout et al.",2,[4],[15.93],15.93,11,10,8,[0,0,0,0,0,0,0,0,0,0,3,1,1,3,2,0],"10.1097/MCG.0000000000001214"],[32113854,"The 2020 update of the CEAP classification system and reporting standards.","J Vasc Surg Venous Lymphat Disord",2020,"Lurie et al.",4,[0],[15.93],15.93,10,10,8,[0,0,0,0,0,0,0,0,0,0,0,1,2,3,3,1],"10.1016/j.jvsv.2019.12.075"],[32469182,"Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer.","N Engl J Med",2020,"Shitara et al.",2,[1,4],[15.93,15.93],15.93,12,10,8,[0,0,0,0,0,0,0,0,0,0,0,2,1,3,2,4],"10.1056/NEJMoa2004413"],[33441402,"Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and 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Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma.","N Engl J Med",2021,"Choueiri et al.",2,[1,8],[15.93,15.93],15.93,12,10,8,[0,0,0,0,0,0,0,0,0,0,0,2,1,4,3,2],"10.1056/NEJMoa2106391"],[17368153,"Cardiopulmonary resuscitation by bystanders with chest compression only (SOS-KANTO): an observational study.","Lancet",2007,"SOS-KANTO study group",5,[0],[15.45],15.91,15,14,5,[2,1,2,1,4,0,0,0,0,0,0,0,0,2,3,0],"10.1016/S0140-6736(07)60451-6"],[947585,"Letter: Grading of angina pectoris.","Circulation",1976,"Campeau",7,[0],[15.05],15.87,23,14,4,[4,5,2,1,2,2,0,0,0,1,0,1,0,0,1,0],""],[17984166,"Rosuvastatin in older patients with systolic heart failure.","N Engl J Med",2007,"Kjekshus et al.",2,[0],[15.45],15.87,28,13,5,[1,1,1,2,0,3,3,1,3,0,0,1,0,0,0,1],"10.1056/NEJMoa0706201"],[18984774,"Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the Fenofibrate Intervention and Event Lowering in 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A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue').","Gastroenterology",1992,"Marsh",6,[4,7],[15.78,13.27],15.78,9,8,8,[0,0,2,1,1,2,1,1,0,0,0,0,0,0,1,0],""],[3344163,"Pain in children: comparison of assessment scales.","Pediatr Nurs",1988,"Wong et al.",7,[16],[2.69],15.78,8,8,8,[0,2,1,0,0,0,1,0,1,1,0,1,0,1,0,0],""],[7768369,"Endoscopically removed malignant colorectal polyps: clinicopathologic correlations.","Gastroenterology",1995,"Cooper et al.",7,[1,4],[15.78,15.78],15.78,10,8,9,[1,1,1,0,1,0,0,0,0,1,0,1,0,0,2,0],"10.1016/0016-5085(95)90126-4"],[8583588,"Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study.","J Urol",1996,"Borghi et al.",2,[8],[13.27],15.78,8,8,8,[1,1,0,1,0,1,0,0,1,0,0,0,0,1,2,0],""],[8831595,"Randomized trial comparing albumin, dextran 70, and polygeline in cirrhotic patients with ascites treated by paracentesis.","Gastroenterology",1996,"Ginès et al.",2,[4],[10.83],15.78,8,8,8,[0,1,0,0,1,1,1,2,0,0,1,0,0,1,0,0],"10.1016/s0016-5085(96)70068-9"],[9169703,"Pancreatic fluid collections prior to intervention: evaluation with MR imaging compared with CT and US.","Radiology",1997,"Morgan et al.",5,[4],[15.78],15.78,8,8,8,[0,0,1,0,0,2,0,1,0,0,1,1,0,1,0,1],"10.1148/radiology.203.3.9169703"],[9220806,"The FLACC: a behavioral scale for scoring postoperative pain in young children.","Pediatr Nurs",1997,"Merkel et al.",7,[],[],15.78,9,8,8,[0,2,0,1,0,0,1,1,1,2,0,0,0,1,0,0],""],[9683204,"Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group.","Lancet",1998,"Sjöström et al.",2,[7],[13.27],15.78,10,8,8,[0,0,0,0,1,1,0,1,0,0,0,1,1,0,1,2],"10.1016/s0140-6736(97)11509-4"],[9684123,"Water supplementation enhances the effect of high-fiber diet on stool frequency and laxative consumption in adult patients with functional constipation.","Hepatogastroenterology",1998,"Anti et al.",2,[4,5],[9.48,5.08],15.78,11,8,9,[1,0,0,0,0,1,1,1,0,0,0,0,1,2,2,0],""],[9990575,"The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients.","Nutrition",1999,"Vellas et al.",6,[7],[6.2],15.78,8,8,8,[0,1,0,0,0,0,1,0,2,0,1,0,1,0,1,1],"10.1016/s0899-9007(98)00171-3"],[10080844,"Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma.","N Engl J Med",1999,"Lagergren et al.",5,[4,1],[15.78,13.27],15.78,9,8,8,[2,1,1,0,1,1,0,0,1,0,0,2,0,0,0,0],"10.1056/NEJM199903183401101"],[10431991,"Superficial thrombophlebitis of the legs: a randomized, controlled, follow-up study.","Angiology",1999,"Belcaro et al.",2,[0,11],[15.78,0.0],15.78,8,8,8,[0,1,1,0,0,1,0,0,1,0,2,1,0,1,0,0],"10.1177/000331979905000701"],[10509498,"Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures.","Lancet",1999,"Blot et al.",5,[2],[9.02],15.78,9,8,8,[2,1,0,1,1,0,1,1,0,0,0,0,1,0,0,0],"10.1016/s0140-6736(98)11134-0"],[10556107,"A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy.","Am J Respir Crit Care Med",1999,"Dirksen et al.",2,[3],[13.27],15.78,8,8,8,[0,2,1,0,0,0,1,0,0,1,0,1,0,1,1,0],"10.1164/ajrccm.160.5.9901055"],[10733441,"Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial.","Ann Intern Med",2000,"Badesch et al.",2,[0,3,14],[10.83,9.02,6.2],15.78,10,8,8,[1,0,1,0,1,2,2,1,0,0,0,0,0,0,0,1],"10.7326/0003-4819-132-6-200003210-00002"],[10737275,"Predictors of recurrence after deep vein thrombosis and pulmonary embolism: a population-based cohort study.","Arch Intern Med",2000,"Heit et al.",7,[0,3],[15.78,6.77],15.78,8,8,8,[1,1,1,0,1,2,0,1,0,0,0,0,0,0,1,0],"10.1001/archinte.160.6.761"],[10891514,"Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland.","N Engl J Med",2000,"Lichtenstein et al.",5,[1],[15.78],15.78,11,8,11,[0,0,1,1,0,0,0,1,2,1,0,0,0,1,0,1],"10.1056/NEJM200007133430201"],[10922422,"Hepatic iron concentration and total body iron stores in thalassemia major.","N Engl J Med",2000,"Angelucci et al.",7,[17,10],[11.38,6.77],15.78,8,8,8,[1,0,2,0,0,1,0,0,1,1,0,0,0,1,1,0],"10.1056/NEJM200008033430503"],[11740700,"Immunogenicity and safety of pneumococcal 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al.",5,[0],[13.81],15.78,9,8,8,[1,2,0,0,2,0,0,1,0,1,0,0,0,1,0,1],"10.7326/0003-4819-136-12-200206180-00007"],[12094370,"Diagnosis of gastrointestinal stromal tumors: A consensus approach.","Hum Pathol",2002,"Fletcher et al.",4,[1,4],[15.78,13.27],15.78,8,8,8,[0,2,1,0,0,1,1,0,1,0,0,0,0,1,1,0],"10.1053/hupa.2002.123545"],[12351602,"Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival.","J Clin Oncol",2002,"Smith et al.",2,[1],[11.84],15.78,11,8,8,[3,1,1,0,0,1,0,1,2,0,0,0,0,0,2,0],"10.1200/JCO.2002.02.118"],[12395331,"Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus.","Hepatology",2002,"Hassan et al.",7,[4,1,2],[15.78,6.77,2.69],15.78,8,8,8,[0,0,0,2,1,0,0,0,1,1,1,0,0,1,0,1],"10.1053/jhep.2002.36780"],[12405362,"Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized study.","J Neurosurg",2002,"Hillman et al.",2,[0,5],[15.78,10.83],15.78,8,8,8,[1,2,1,1,0,0,0,0,0,0,1,1,0,0,0,1],"10.3171/jns.2002.97.4.0771"],[13760840,"An assessment of prednisone, salazopyrin, and topical hydrocortisone hemisuccinate used as out-patient treatment for ulcerative colitis.","Gut",1960,"LENNARD-JONES et al.",7,[4],[15.78],15.78,9,8,8,[2,2,0,0,1,0,1,1,0,0,0,0,1,1,0,0],"10.1136/gut.1.3.217"],[14596315,"Quality assurance for computed-tomography simulators and the computed-tomography-simulation process: report of the AAPM Radiation Therapy Committee Task Group No. 66.","Med Phys",2003,"Mutic et al.",7,[1],[10.68],15.78,11,10,7,[0,1,0,0,0,0,1,0,0,2,2,2,1,0,2,0],"10.1118/1.1609271"],[15128990,"Are two-dimensional CT measurements of small noncalcified pulmonary nodules reliable?","Radiology",2004,"Revel et al.",7,[3],[15.78],15.78,8,8,8,[0,1,1,0,1,2,0,1,0,0,0,0,1,0,0,1],"10.1148/radiol.2312030167"],[15166961,"Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases.","Ann Surg",2004,"Abdalla et al.",5,[1,4],[15.78,15.78],15.78,10,8,8,[3,0,1,0,0,1,1,0,0,1,1,0,0,0,1,0],"10.1097/01.sla.0000128305.90650.71"],[15467584,"A prospective trial that demonstrates that dalteparin requirements increase in pregnancy to maintain therapeutic levels of anticoagulation.","Am J Obstet Gynecol",2004,"Barbour et al.",3,[0,9],[15.78,11.38],15.78,10,8,8,[1,2,0,1,0,1,0,2,0,0,0,0,0,1,0,1],"10.1016/j.ajog.2004.05.050"],[15530628,"Regression of low-grade squamous intra-epithelial lesions in young women.","Lancet",2004,"Moscicki et al.",5,[1,9,2],[15.78,13.27,4.65],15.78,9,8,8,[0,1,2,1,0,1,0,0,0,1,0,0,1,1,0,0],"10.1016/S0140-6736(04)17354-6"],[15592814,"Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle.","Intensive Care Med",2005,"Simpson et al.",0,[2],[9.02],15.78,12,8,8,[1,0,1,1,1,2,0,0,0,1,1,0,0,0,0,0],"10.1007/s00134-004-2511-2"],[15855432,"Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.","JAMA",2005,"Piñol et al.",5,[1,4,7],[15.78,13.27,11.38],15.78,12,8,11,[1,0,2,1,2,1,0,0,1,0,0,0,0,0,0,1],"10.1001/jama.293.16.1986"],[15939805,"Superiority of ambulatory over clinic blood pressure measurement in predicting mortality: the Dublin outcome study.","Hypertension",2005,"Dolan et al.",7,[0],[15.78],15.78,10,8,8,[0,1,1,0,1,0,0,0,2,0,0,1,0,0,1,1],"10.1161/01.HYP.0000170138.56903.7a"],[15992696,"Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial.","Lancet Oncol",2005,"Veldkamp et al.",2,[4,1],[9.02,6.77],15.78,9,8,7,[0,1,2,0,0,0,1,0,0,1,0,0,2,1,1,0],"10.1016/S1470-2045(05)70221-7"],[16169887,"Diagnostic performance of digital versus film mammography for breast-cancer screening.","N Engl J Med",2005,"Pisano et al.",3,[1],[13.81],15.78,9,8,8,[1,0,1,1,2,2,1,0,0,0,1,0,0,0,0,0],"10.1056/NEJMoa052911"],[16224214,"Pathologic features and clinical significance of \"backwash\" ileitis in ulcerative colitis.","Am J Surg Pathol",2005,"Haskell et al.",5,[4],[15.78],15.78,8,8,8,[0,1,2,1,1,0,1,0,0,1,0,0,0,0,1,0],"10.1097/01.pas.0000176435.19197.88"],[16227328,"Clinical efficacy of anti-pneumococcal vaccination in patients with COPD.","Thorax",2006,"Alfageme et al.",2,[2,3],[4.65,13.81],15.78,9,8,8,[1,1,1,0,2,0,1,0,0,1,0,0,1,0,0,0],"10.1136/thx.2005.043323"],[16258083,"Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31.","J Clin Oncol",2005,"Tan-Chiu et al.",2,[0,1],[6.77,13.81],15.78,10,8,8,[3,2,0,1,1,1,1,0,0,0,0,0,0,1,0,0],"10.1200/JCO.2005.02.4091"],[16285948,"High-dose ursodeoxycholic acid in primary sclerosing cholangitis: a 5-year multicenter, randomized, controlled study.","Gastroenterology",2005,"Olsson et al.",2,[4],[15.78],15.78,8,8,8,[0,0,0,0,2,0,1,1,1,1,0,1,0,0,1,0],"10.1053/j.gastro.2005.08.017"],[16371403,"Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies.","BMJ",2006,"Huxley et al.",0,[0,7],[11.38,8.47],15.78,10,8,8,[1,0,2,2,1,0,0,0,0,0,1,1,0,1,0,0],"10.1136/bmj.38678.389583.7C"],[16484911,"Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury.","Crit Care Med",2006,"Singer et al.",2,[3],[4.65],15.78,10,8,8,[1,0,1,1,0,1,0,1,2,1,0,0,0,0,0,0],"10.1097/01.CCM.0000206111.23629.0A"],[16490089,"The revised FLACC observational pain tool: improved reliability and validity for pain assessment in children with cognitive impairment.","Paediatr Anaesth",2006,"Malviya et al.",7,[6],[1.0],15.78,8,8,8,[0,1,0,1,0,0,0,1,1,1,1,2,0,0,0,0],"10.1111/j.1460-9592.2005.01773.x"],[16513687,"Effectiveness of hip protectors for preventing hip fractures in elderly people: systematic review.","BMJ",2006,"Parker et al.",0,[13],[15.78],15.78,9,8,8,[1,0,2,1,0,1,1,0,2,0,1,0,0,0,0,0],"10.1136/bmj.38753.375324.7C"],[16557151,"A high positive end-expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome: a randomized, controlled trial.","Crit Care Med",2006,"Villar et al.",2,[3],[9.02],15.78,10,8,7,[0,0,0,0,1,0,2,0,1,2,0,1,0,0,1,1],"10.1097/01.CCM.0000215598.84885.01"],[16625008,"Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome.","N Engl J Med",2006,"Steinberg et al.",2,[3],[15.78],15.78,8,8,8,[1,1,0,0,0,1,2,0,1,0,0,1,0,1,0,0],"10.1056/NEJMoa051693"],[16628644,"Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC.","Hepatology",2006,"Corpechot et al.",5,[4],[15.78],15.78,8,8,8,[1,0,0,1,1,0,2,1,1,0,0,0,0,1,0,0],"10.1002/hep.21151"],[16782930,"Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data.","J Clin Oncol",2006,"Wagner et al.",0,[1,4],[15.78,15.78],15.78,9,8,8,[1,1,2,2,0,0,1,0,1,0,0,0,0,0,1,0],"10.1200/JCO.2005.05.0245"],[16817843,"Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses.","Am J Gastroenterol",2006,"Melmed et al.",7,[4],[13.81],15.78,10,8,8,[1,1,0,2,0,0,1,0,0,0,1,1,0,0,2,0],"10.1111/j.1572-0241.2006.00646.x"],[16952543,"A randomized, controlled trial of transanal irrigation versus conservative bowel management in spinal cord-injured patients.","Gastroenterology",2006,"Christensen et al.",2,[4,5,13],[15.78,2.69,1.0],15.78,9,8,9,[0,0,0,1,1,0,1,2,0,0,1,1,0,0,0,1],"10.1053/j.gastro.2006.06.004"],[17056862,"Derivation of the children's head injury algorithm for the prediction of important clinical events decision rule for head injury in children.","Arch Dis Child",2006,"Dunning et al.",5,[5,13],[15.78,15.78],15.78,11,8,9,[0,2,0,2,0,1,0,1,0,1,1,0,0,1,0,0],"10.1136/adc.2005.083980"],[17131776,"False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria?","Int J Tuberc Lung Dis",2006,"Farhat et al.",0,[2],[10.83],15.78,8,8,8,[1,1,0,0,1,0,0,1,1,0,2,0,0,0,1,0],""],[17342642,"Antibiotic prophylaxis and the risk of surgical site infections following total hip arthroplasty: timely administration is the most important factor.","Clin Infect Dis",2007,"van Kasteren et al.",5,[2],[11.38],15.78,9,8,9,[1,0,1,1,0,0,2,1,1,0,0,0,0,0,0,1],"10.1086/512192"],[17383417,"Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis.","Gastroenterology",2007,"Kiesslich et al.",2,[4,1],[15.78,4.65],15.78,10,8,10,[0,0,1,2,2,0,0,1,1,0,0,0,1,1,0,0],"10.1053/j.gastro.2007.01.048"],[17512669,"Seeding following percutaneous diagnostic and therapeutic approaches for hepatocellular carcinoma. What is the risk and the outcome? Seeding risk for percutaneous approach of HCC.","Cancer Treat Rev",2007,"Stigliano et al.",6,[1,4],[15.78,15.78],15.78,13,8,10,[0,2,0,0,1,2,0,1,1,0,1,2,0,0,0,0],"10.1016/j.ctrv.2007.04.001"],[17803871,"Prophylaxis of Pneumocystis pneumonia in immunocompromised non-HIV-infected patients: systematic review and meta-analysis of randomized controlled trials.","Mayo Clin Proc",2007,"Green et al.",0,[2,3],[8.47,6.2],15.78,9,8,8,[1,1,1,0,0,3,0,1,0,1,0,0,0,1,0,0],"10.4065/82.9.1052"],[18184959,"Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.","N Engl J Med",2008,"Bissler et al.",3,[1,5,17],[13.81,7.22,7.22],15.78,9,8,9,[0,2,1,1,0,2,0,0,1,0,0,0,1,0,1,0],"10.1056/NEJMoa063564"],[18272546,"Randomised trial of once- or twice-daily MMX mesalazine for maintenance of remission in ulcerative colitis.","Gut",2008,"Kamm et al.",2,[4],[15.78],15.78,9,8,8,[2,2,1,0,1,0,1,0,0,0,0,0,1,1,0,0],"10.1136/gut.2007.138248"],[18582928,"Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial.","Lancet",2008,"Kakkar et al.",2,[0],[15.78],15.78,9,8,8,[1,1,1,0,1,0,1,3,1,0,0,0,0,0,0,0],"10.1016/S0140-6736(08)60880-6"],[18593759,"Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade.","Ann Rheum Dis",2009,"Smolen et al.",2,[11],[15.78],15.78,8,8,8,[2,1,1,1,1,0,1,1,0,0,0,0,0,0,0,0],"10.1136/ard.2008.090019"],[18691580,"Polyp size and advanced histology in patients undergoing colonoscopy screening: implications for CT colonography.","Gastroenterology",2008,"Lieberman et al.",7,[1,4],[15.78,15.78],15.78,13,10,8,[0,4,1,2,1,0,0,1,0,1,1,0,0,0,0,0],"10.1053/j.gastro.2008.06.083"],[18752324,"Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis.","Hepatology",2008,"Corpechot et al.",5,[4],[15.78],15.78,8,8,8,[0,0,0,0,1,0,0,1,1,1,0,1,0,1,0,2],"10.1002/hep.22428"],[18791365,"Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients.","Ann Surg",2008,"Holcomb et al.",5,[13],[9.02],15.78,8,8,8,[1,1,2,0,0,1,1,1,0,0,0,0,0,0,1,0],"10.1097/SLA.0b013e318185a9ad"],[19125127,"EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome.","Genet Med",2009,"Palomaki et al.",6,[1,4,17],[15.78,11.84,11.38],15.78,12,8,11,[0,1,1,1,3,1,0,0,1,1,0,0,0,0,0,0],"10.1097/GIM.0b013e31818fa2db"],[19129525,"Timing of elective repeat cesarean delivery at term and neonatal outcomes.","N Engl J Med",2009,"Tita et al.",5,[17],[1.0],15.78,9,8,8,[0,0,0,0,2,0,1,1,1,0,1,0,0,1,1,0],"10.1056/NEJMoa0803267"],[19332714,"Late mortality among 5-year survivors of childhood cancer: a summary from the Childhood Cancer Survivor Study.","J Clin Oncol",2009,"Armstrong et al.",5,[1],[15.78],15.78,9,8,8,[0,2,1,0,1,0,0,1,0,1,1,0,2,0,0,0],"10.1200/JCO.2008.21.1425"],[19352345,"A global, evidence-based consensus on the definition of gastroesophageal reflux disease in the pediatric population.","Am J Gastroenterol",2009,"Sherman et al.",4,[4],[10.83],15.78,8,8,8,[0,1,0,1,0,0,0,1,1,0,1,0,0,2,0,1],"10.1038/ajg.2009.129"],[19419331,"A Multicenter, double-blind trial of a high-dose caspofungin treatment regimen versus a standard caspofungin treatment regimen for adult patients with invasive candidiasis.","Clin Infect Dis",2009,"Betts et al.",2,[2],[15.78],15.78,10,8,9,[2,1,1,1,0,1,1,0,0,0,0,0,0,0,0,1],"10.1086/598933"],[19501587,"Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo.","Gastroenterology",2009,"Sharma et al.",2,[4,5,7],[15.78,9.02,9.02],15.78,9,8,9,[1,1,0,1,0,0,0,0,1,1,0,0,2,0,0,1],"10.1053/j.gastro.2009.05.056"],[19552948,"Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study.","Lancet",2009,"Schmid et al.",5,[1,9],[15.78,15.78],15.78,9,8,8,[0,0,1,0,1,0,0,1,1,0,2,0,0,0,1,1],"10.1016/S0140-6736(09)60618-8"],[19710031,"Increased colorectal cancer risk during follow-up in patients with hyperplastic polyposis syndrome: a multicentre cohort study.","Gut",2010,"Boparai et al.",7,[4,1],[15.78,13.27],15.78,8,8,8,[0,1,0,1,1,0,1,0,2,1,1,0,0,0,0,0],"10.1136/gut.2009.185884"],[19710483,"Exposure to low-dose ionizing radiation from medical imaging procedures.","N Engl J Med",2009,"Fazel et al.",5,[0],[13.27],15.78,8,8,8,[1,0,2,1,1,0,0,1,0,0,1,1,0,0,0,0],"10.1056/NEJMoa0901249"],[19797283,"Variation in hospital mortality associated with inpatient surgery.","N Engl J Med",2009,"Ghaferi et al.",7,[0],[6.2],15.78,9,8,8,[2,0,1,1,1,1,1,0,0,0,0,0,0,0,1,0],"10.1056/NEJMsa0903048"],[19797342,"Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials.","BMJ",2009,"Bischoff-Ferrari et al.",0,[7,13],[9.48,9.48],15.78,10,8,8,[2,0,1,1,0,1,2,0,2,1,0,0,0,0,0,0],"10.1136/bmj.b3692"],[19812868,"Validation of the Mini Nutritional Assessment short-form (MNA-SF): a practical tool for identification of nutritional status.","J Nutr Health Aging",2009,"Kaiser et al.",7,[7],[10.83],15.78,9,8,8,[0,0,0,0,2,0,2,1,1,1,0,1,0,0,1,0],"10.1007/s12603-009-0214-7"],[19828530,"The clinical course of advanced dementia.","N Engl J Med",2009,"Mitchell et al.",5,[5,6],[10.83,10.83],15.78,8,8,8,[0,1,1,1,2,0,0,0,1,1,0,0,0,1,0,0],"10.1056/NEJMoa0902234"],[20031794,"Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review.","Circ Cardiovasc Qual Outcomes",2008,"Wan et al.",1,[0],[15.78],15.78,14,8,8,[0,1,0,0,0,1,1,1,0,1,0,2,0,3,0,0],"10.1161/CIRCOUTCOMES.108.796185"],[20051569,"Antidepressant drug effects and depression severity: a patient-level meta-analysis.","JAMA",2010,"Fournier et al.",0,[6],[8.47],15.78,8,8,8,[0,1,1,1,2,1,0,0,1,0,0,0,1,0,0,0],"10.1001/jama.2009.1943"],[20064207,"Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT.","Arthritis Res Ther",2010,"Strangfeld et al.",5,[1,11],[0.0,13.27],15.78,8,8,8,[1,2,0,0,0,0,1,0,1,1,0,0,0,1,1,0],"10.1186/ar2904"],[20157136,"Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study.","Ann Intern Med",2010,"Decousus et al.",5,[0,3],[15.78,0.0],15.78,8,8,8,[1,2,1,0,0,1,0,0,0,0,1,1,0,1,0,0],"10.7326/0003-4819-152-4-201002160-00006"],[20196634,"Low-dose vaginal estrogens or vaginal moisturizer in breast cancer survivors with urogenital atrophy: a preliminary study.","Gynecol Endocrinol",2010,"Biglia et al.",7,[1],[6.77],15.78,9,8,8,[0,1,0,1,1,0,1,1,1,0,2,0,0,0,0,0],"10.3109/09513591003632258"],[20200926,"Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial.","J Bone Miner Res",2010,"Schwartz et al.",2,[13],[15.78],15.78,9,8,8,[0,1,2,0,0,1,1,0,1,2,0,0,0,1,0,0],"10.1002/jbmr.11"],[20206180,"One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome.","Gastroenterology",2010,"Vasen et al.",7,[1,4,7],[15.78,13.27,9.02],15.78,11,8,11,[0,0,1,2,1,0,0,1,1,1,0,0,0,0,0,1],"10.1053/j.gastro.2010.02.053"],[20305451,"Endorectal advancement flap for cryptoglandular or Crohn's fistula-in-ano.","Dis Colon Rectum",2010,"Soltani et al.",1,[4],[15.78],15.78,8,8,8,[1,0,0,1,1,1,0,2,0,1,0,0,0,0,0,1],"10.1007/DCR.0b013e3181ce8b01"],[20351233,"Risk assessment of recurrence in patients with unprovoked deep vein thrombosis or pulmonary embolism: the Vienna prediction model.","Circulation",2010,"Eichinger et al.",5,[0,3],[15.78,6.77],15.78,8,8,8,[1,2,1,0,0,0,0,0,1,1,1,0,0,1,0,0],"10.1161/CIRCULATIONAHA.109.925214"],[20530299,"Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study.","Hypertension",2010,"Ogihara et al.",2,[0],[15.78],15.78,10,8,8,[0,0,1,1,2,1,1,0,1,0,0,0,0,0,0,1],"10.1161/HYPERTENSIONAHA.109.146035"],[20598363,"Pre-eclampsia.","Lancet",2010,"Steegers et al.",6,[9],[13.81],15.78,11,8,8,[1,2,0,0,0,2,1,0,1,1,0,0,0,2,0,0],"10.1016/S0140-6736(10)60279-6"],[20679551,"Induction of therapeutic hypothermia by paramedics after resuscitation from out-of-hospital ventricular fibrillation cardiac arrest: a randomized controlled trial.","Circulation",2010,"Bernard et al.",2,[0],[13.27],15.78,9,8,8,[0,0,0,0,3,1,1,1,0,1,1,0,0,0,0,1],"10.1161/CIRCULATIONAHA.109.906859"],[20801772,"Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease.","Gut",2010,"McPherson et al.",7,[4],[13.81],15.78,8,8,8,[0,0,0,0,1,0,0,1,0,0,1,0,1,1,2,1],"10.1136/gut.2010.216077"],[21099592,"Contemporary patterns of spontaneous labor with normal neonatal outcomes.","Obstet Gynecol",2010,"Zhang et al.",7,[9],[13.81],15.78,9,8,9,[0,0,0,0,0,0,1,2,1,1,0,0,1,1,1,0],"10.1097/AOG.0b013e3181fdef6e"],[21119508,"The prevalence of lymph node metastases in patients with T1 esophageal adenocarcinoma a retrospective review of esophagectomy specimens.","Ann Surg",2011,"Leers et al.",7,[1,4],[15.78,15.78],15.78,8,8,8,[0,0,0,0,1,1,0,1,2,1,0,0,0,1,1,0],"10.1097/SLA.0b013e3181fbad42"],[21237454,"Direct endoscopic necrosectomy for the treatment of walled-off pancreatic necrosis: results from a multicenter U.S. series.","Gastrointest Endosc",2011,"Gardner et al.",3,[4],[15.78],15.78,8,8,8,[0,0,1,0,2,1,1,0,0,0,1,1,0,1,0,0],"10.1016/j.gie.2010.10.053"],[21396370,"Long-term outcomes of patients with autoimmune hepatitis managed at a nontransplant center.","Gastroenterology",2011,"Hoeroldt et al.",5,[4],[15.78],15.78,9,8,8,[1,0,0,0,1,0,1,0,0,1,0,1,1,0,3,0],"10.1053/j.gastro.2011.02.065"],[21639806,"Exemestane for breast-cancer prevention in postmenopausal women.","N Engl J Med",2011,"Goss et al.",2,[1],[15.78],15.78,9,8,8,[0,0,0,0,2,1,1,0,2,0,1,0,0,1,1,0],"10.1056/NEJMoa1103507"],[21703194,"Early primary biliary cirrhosis: biochemical response to treatment and prediction of long-term outcome.","J Hepatol",2011,"Corpechot et al.",5,[4],[15.78],15.78,8,8,8,[0,0,0,0,1,0,1,1,1,1,0,1,0,0,0,2],"10.1016/j.jhep.2011.02.031"],[21788214,"Health supervision for children with Down syndrome.","Pediatrics",2011,"Bull et al.",7,[5,17],[6.77,2.69],15.78,8,8,8,[0,0,2,0,1,0,1,0,0,0,0,0,1,1,1,1],"10.1542/peds.2011-1605"],[21865942,"First report from the American College of Surgeons Bariatric Surgery Center Network: laparoscopic sleeve gastrectomy has morbidity and effectiveness positioned between the band and the bypass.","Ann Surg",2011,"Hutter et al.",5,[7],[13.81],15.78,10,8,9,[0,1,1,0,0,0,1,2,1,1,0,1,0,0,0,0],"10.1097/SLA.0b013e31822c9dac"],[21895039,"Rivaroxaban: population pharmacokinetic analyses in patients treated for acute deep-vein thrombosis and exposure simulations in patients with atrial fibrillation treated for stroke prevention.","Clin Pharmacokinet",2011,"Mueck et al.",2,[0,5],[13.81,5.41],15.78,11,8,9,[0,0,2,2,1,1,0,2,0,0,1,0,0,0,1,0],"10.2165/11595320-000000000-00000"],[21976398,"Efficacy and safety of enteric-coated mycophenolate sodium in combination with two glucocorticoid regimens for the treatment of active lupus nephritis.","Lupus",2011,"Zeher et al.",2,[11,8],[15.78,8.47],15.78,11,8,9,[0,2,1,0,0,1,0,0,0,0,1,0,0,2,1,1],"10.1177/0961203311418269"],[21998060,"Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran.","Stroke",2011,"Zhou et al.",7,[0,5],[13.27,6.77],15.78,11,8,10,[0,0,3,1,1,0,0,1,0,1,0,0,0,1,0,1],"10.1161/STROKEAHA.111.624650"],[22006311,"Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.","Proc Natl Acad Sci U S A",2011,"Walsh et al.",7,[1,9,7],[15.78,11.38,9.02],15.78,8,8,8,[0,0,0,0,2,1,1,1,0,1,0,0,0,1,1,0],"10.1073/pnas.1115052108"],[22029981,"Long-term persistence of hormonal adaptations to weight loss.","N Engl J Med",2011,"Sumithran et al.",3,[7],[15.78],15.78,9,8,9,[0,0,1,0,1,2,0,0,0,2,1,1,1,0,0,0],"10.1056/NEJMoa1105816"],[22031356,"Likelihood of malignancy in gallbladder polyps and outcomes following cholecystectomy in primary sclerosing cholangitis.","Am J Gastroenterol",2012,"Eaton et al.",5,[4,1],[15.78,6.77],15.78,9,8,8,[0,0,0,0,2,0,2,1,0,0,0,1,1,1,0,1],"10.1038/ajg.2011.361"],[22245846,"Frequent detection of pancreatic lesions in asymptomatic high-risk individuals.","Gastroenterology",2012,"Canto et al.",5,[4,1,7],[15.78,13.27,13.27],15.78,8,8,8,[0,0,1,0,1,2,0,0,1,1,0,0,0,1,0,1],"10.1053/j.gastro.2012.01.005"],[22248661,"Effects of fractionated plasma separation and adsorption on survival in patients with acute-on-chronic liver failure.","Gastroenterology",2012,"Kribben et al.",2,[4],[15.78],15.78,8,8,8,[0,0,0,0,1,2,1,1,0,1,0,0,0,1,0,1],"10.1053/j.gastro.2011.12.056"],[22258955,"Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy.","Cochrane Database Syst Rev",2012,"Gafter-Gvili et al.",0,[2,10],[11.38,1.35],15.78,9,8,8,[0,0,1,1,2,0,0,1,0,0,1,0,0,2,1,0],"10.1002/14651858.CD004386.pub3"],[22344575,"A randomized placebo-controlled trial of methotrexate in psoriatic arthritis.","Rheumatology (Oxford)",2012,"Kingsley et al.",2,[11,14,13],[11.84,13.27,11.84],15.78,10,8,8,[0,0,0,1,0,1,1,1,2,2,0,0,0,0,1,0],"10.1093/rheumatology/kes001"],[22470079,"Timing of cholecystectomy after mild biliary pancreatitis: a systematic review.","Ann Surg",2012,"van Baal et al.",1,[4],[15.78],15.78,8,8,8,[0,0,1,0,1,0,2,1,1,0,0,0,0,1,0,1],"10.1097/SLA.0b013e3182507646"],[22522090,"Decreasing risk of colorectal cancer in patients with inflammatory bowel disease over 30 years.","Gastroenterology",2012,"Jess et al.",5,[4,1],[15.78,8.47],15.78,8,8,8,[0,0,1,1,1,1,0,1,0,1,2,0,0,0,0,0],"10.1053/j.gastro.2012.04.016"],[22572686,"Ultrasound of colon diverticulitis.","Dig Dis",2012,"Puylaert",6,[4],[13.27],15.78,9,8,8,[0,0,0,1,2,0,1,1,0,1,0,1,0,1,0,0],"10.1159/000336620"],[23085647,"Improvement of serum alkaline phosphatase to <1.5 upper limit of normal predicts better outcome and reduced risk of cholangiocarcinoma in primary sclerosing cholangitis.","J Hepatol",2013,"Al Mamari et al.",5,[4,1],[15.78,4.65],15.78,8,8,8,[0,0,0,0,2,0,1,1,1,0,0,1,0,1,0,1],"10.1016/j.jhep.2012.10.013"],[23232048,"Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis.","Gut",2013,"Hart et al.",7,[4],[13.27],15.78,8,8,8,[0,0,0,1,2,0,1,0,1,1,0,1,0,0,0,1],"10.1136/gutjnl-2012-303617"],[23235597,"Erythropoietin or darbepoetin for patients with cancer.","Cochrane Database Syst Rev",2012,"Tonia et al.",0,[1,10],[13.27,11.38],15.78,8,8,8,[0,0,0,0,1,0,0,1,2,1,1,1,0,1,0,0],"10.1002/14651858.CD003407.pub5"],[23352693,"Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis.","Lancet Infect Dis",2013,"Daneman et al.",0,[2],[13.81],15.78,8,8,8,[0,0,0,1,1,2,1,1,1,0,1,0,0,0,0,0],"10.1016/S1473-3099(12)70322-5"],[23406914,"Palliative use of non-invasive ventilation in end-of-life patients with solid tumours: a randomised feasibility trial.","Lancet Oncol",2013,"Nava et al.",2,[3,1],[13.27,4.65],15.78,8,8,8,[0,0,0,1,0,1,0,0,0,2,1,0,0,1,1,1],"10.1016/S1470-2045(13)70009-3"],[23450544,"Lung protective ventilation strategy for the acute respiratory distress syndrome.","Cochrane Database Syst Rev",2013,"Petrucci et al.",0,[3],[11.38],15.78,11,8,9,[0,0,0,0,1,0,2,1,2,1,0,0,0,2,0,1],"10.1002/14651858.CD003844.pub4"],[23774337,"Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense.","Crit Care Med",2013,"Marik et al.",0,[0],[4.65],15.78,8,8,8,[0,0,0,0,1,1,1,2,0,1,0,0,1,0,1,0],"10.1097/CCM.0b013e31828a25fd"],[23811638,"Are there any differences in the efficacy and safety of different formulations of Oral 5-ASA used for induction and maintenance of remission in ulcerative colitis? evidence from cochrane reviews.","Inflamm Bowel Dis",2013,"Feagan et al.",6,[4],[15.78],15.78,11,8,9,[0,0,0,0,1,0,2,2,1,0,0,0,1,1,2,0],"10.1097/MIB.0b013e3182920108"],[23883378,"Riociguat for the treatment of pulmonary arterial hypertension.","N Engl J Med",2013,"Ghofrani et al.",2,[3,0],[13.27,10.83],15.78,12,8,8,[0,0,0,0,1,2,1,1,0,0,0,0,0,1,2,2],"10.1056/NEJMoa1209655"],[23999929,"Clinical pharmacokinetic and pharmacodynamic profile of rivaroxaban.","Clin Pharmacokinet",2014,"Mueck et al.",6,[0,5],[11.38,4.65],15.78,8,8,8,[0,0,0,0,1,1,0,1,0,1,1,0,0,1,2,0],"10.1007/s40262-013-0100-7"],[24088092,"Long-term cognitive impairment after critical illness.","N Engl J Med",2013,"Pandharipande et al.",3,[6,3],[4.65,2.0],15.78,8,8,7,[0,0,0,1,1,0,0,1,0,2,0,1,1,0,1,0],"10.1056/NEJMoa1301372"],[24192252,"Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials.","Lancet",2014,"Ronco et al.",7,[9,1,2],[15.78,13.27,8.47],15.78,8,8,8,[0,0,0,0,1,0,1,1,0,1,0,0,1,1,2,0],"10.1016/S0140-6736(13)62218-7"],[24210621,"Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1,866 adult patients.","Ann Thorac Surg",2014,"Cheng et al.",0,[0],[15.78],15.78,12,8,9,[0,0,0,0,0,0,0,1,0,1,1,0,1,1,1,2],"10.1016/j.athoracsur.2013.09.008"],[24321209,"Good maternal and fetal outcomes for pregnant women with primary biliary cirrhosis.","Clin Gastroenterol Hepatol",2014,"Trivedi et al.",5,[4,9],[13.81,4.04],15.78,8,8,8,[0,0,0,0,1,2,1,1,0,0,1,0,1,0,0,1],"10.1016/j.cgh.2013.11.030"],[24687000,"Effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality, cardiovascular deaths, and cardiovascular events in patients with diabetes mellitus: a meta-analysis.","JAMA Intern Med",2014,"Cheng et al.",0,[0,7],[6.77,6.77],15.78,8,8,8,[0,0,0,0,1,0,0,1,2,1,1,1,0,0,0,1],"10.1001/jamainternmed.2014.348"],[24691607,"Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis.","JAMA",2014,"Rohde et al.",0,[2],[0.0],15.78,8,8,8,[0,0,0,0,1,1,0,2,0,1,1,0,0,1,1,0],"10.1001/jama.2014.2726"],[24941177,"Tofacitinib versus methotrexate in rheumatoid arthritis.","N Engl J Med",2014,"Lee et al.",2,[11],[15.78],15.78,9,8,8,[0,0,0,0,2,1,1,1,1,0,1,0,0,1,0,0],"10.1056/NEJMoa1310476"],[25215556,"Reassessment of fracture risk in women after 3 years of treatment with zoledronic acid: when is it reasonable to discontinue treatment?","J Clin Endocrinol Metab",2014,"Cosman et al.",2,[13],[15.78],15.78,11,8,8,[0,0,0,1,0,1,0,0,2,1,0,2,0,2,1,0],"10.1210/jc.2014-1971"],[25267738,"Optimal duration of low molecular weight heparin for the treatment of cancer-related deep vein thrombosis: the Cancer-DACUS Study.","J Clin Oncol",2014,"Napolitano et al.",2,[0,1],[15.78,10.16],15.78,11,8,8,[0,0,0,0,0,1,0,0,1,1,2,0,1,3,1,0],"10.1200/JCO.2013.51.7433"],[25269391,"Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients.","Cochrane Database Syst Rev",2014,"Stern et al.",0,[3,2],[2.69,1.0],15.78,9,8,9,[0,0,0,0,0,0,0,0,1,2,1,0,1,1,2,1],"10.1002/14651858.CD005590.pub3"],[25287829,"Hepatitis B reactivation in patients with previous hepatitis B virus exposure undergoing rituximab-containing chemotherapy for lymphoma: a prospective study.","J Clin Oncol",2014,"Seto et al.",5,[1,10],[6.77,4.65],15.78,8,8,8,[0,0,0,0,1,1,1,1,0,1,1,0,0,0,2,0],"10.1200/JCO.2014.56.7081"],[25500422,"Whole-breast irradiation with or without a boost for patients treated with breast-conserving surgery for early breast cancer: 20-year follow-up of a randomised phase 3 trial.","Lancet Oncol",2015,"Bartelink et al.",2,[1],[15.78],15.78,12,8,8,[0,0,0,0,1,3,0,1,1,1,1,0,0,2,0,0],"10.1016/S1470-2045(14)71156-8"],[25805204,"Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis.","BMJ",2015,"Holst et al.",0,[7,10],[4.65,4.65],15.78,10,8,8,[0,0,0,0,1,2,1,1,2,0,1,0,0,1,0,0],"10.1136/bmj.h1354"],[25836986,"Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis.","Gastroenterology",2015,"Rossen et al.",2,[4],[9.48],15.78,11,8,7,[0,0,0,0,1,0,0,2,1,0,1,0,1,2,1,0],"10.1053/j.gastro.2015.03.045"],[25857665,"Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial.","Gastroenterology",2015,"Moayyedi et al.",2,[4],[9.48],15.78,12,8,7,[0,0,0,0,1,0,0,2,1,0,1,0,1,2,2,0],"10.1053/j.gastro.2015.04.001"],[26122803,"Umbilical Cord Milking Versus Delayed Cord Clamping in Preterm Infants.","Pediatrics",2015,"Katheria et al.",2,[17,0],[10.83,4.65],15.78,10,8,9,[0,0,0,0,1,1,3,0,0,1,0,1,0,0,1,1],"10.1542/peds.2015-0368"],[26299413,"Minimal hepatic encephalopathy and critical flicker frequency are associated with survival of patients with cirrhosis.","Gastroenterology",2015,"Ampuero et al.",5,[4,5,7],[15.78,6.77,6.77],15.78,8,8,8,[0,0,0,0,0,0,0,0,1,1,0,1,1,1,2,1],"10.1053/j.gastro.2015.07.067"],[26324357,"American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility.","J Clin Oncol",2015,"Robson et al.",7,[1],[13.81],15.78,10,10,7,[0,0,0,0,0,0,1,1,1,3,1,0,0,2,1,0],"10.1200/JCO.2015.63.0996"],[26417845,"Managing synchronous liver metastases from colorectal cancer: a multidisciplinary international consensus.","Cancer Treat Rev",2015,"Adam et al.",4,[1,4],[15.78,15.78],15.78,10,8,8,[0,0,0,0,0,0,0,1,1,3,0,0,1,1,2,1],"10.1016/j.ctrv.2015.06.006"],[26460661,"Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial.","Lancet",2015,"da Costa et al.",2,[4],[15.78],15.78,8,8,8,[0,0,0,0,0,0,1,2,1,0,0,1,0,1,1,1],"10.1016/S0140-6736(15)00274-3"],[26782957,"A randomized clinical trial of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the oesophagus or gastro-oesophageal junction.","Ann Oncol",2016,"Klevebro et al.",2,[1,4],[15.78,15.78],15.78,8,8,8,[0,0,0,0,0,0,0,0,1,1,1,1,1,1,2,0],"10.1093/annonc/mdw010"],[26869575,"Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect.","Lancet",2016,"Victora et al.",0,[7,12,1],[2.69,1.0,0.0],15.78,11,10,7,[0,0,0,0,0,0,1,1,1,2,1,0,0,2,0,2],"10.1016/S0140-6736(15)01024-7"],[27038492,"Hyperthyroidism.","Lancet",2016,"De Leo et al.",6,[7,9],[10.83,0.0],15.78,9,8,8,[0,0,0,0,0,0,0,2,1,2,0,1,1,1,0,1],"10.1016/S0140-6736(16)00278-6"],[27469901,"Observational registry of sorafenib use in clinical practice across Child-Pugh subgroups: The GIDEON study.","J Hepatol",2016,"Marrero et al.",5,[1,4],[15.78,15.78],15.78,13,8,9,[0,0,0,0,0,0,0,0,1,2,1,1,1,3,2,0],"10.1016/j.jhep.2016.07.020"],[28403427,"New Persistent Opioid Use After Minor and Major Surgical Procedures in US Adults.","JAMA Surg",2017,"Brummett et al.",5,[6],[4.65],15.78,8,8,8,[0,0,0,0,0,0,0,1,2,1,1,1,0,1,1,0],"10.1001/jamasurg.2017.0504"],[29132159,"Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.","Ann Intern Med",2018,"Graham et al.",2,[0],[13.27],15.78,10,8,9,[0,0,0,0,0,0,0,1,2,1,0,1,1,1,1,0],"10.7326/M17-2341"],[29756595,"96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection.","J Hepatol",2018,"Agarwal et al.",2,[2,4],[15.78,15.78],15.78,10,8,8,[0,0,0,0,0,0,0,0,1,2,1,1,0,1,1,2],"10.1016/j.jhep.2017.11.039"],[30955977,"Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial.","Lancet",2019,"Mok et al.",2,[1,3],[15.78,15.78],15.78,11,8,8,[0,0,0,0,0,0,0,0,1,1,1,1,3,2,1,0],"10.1016/S0140-6736(18)32409-7"],[11153730,"Age-predicted maximal heart rate revisited.","J Am Coll Cardiol",2001,"Tanaka et al.",0,[0],[8.97],15.77,12,9,7,[1,1,1,0,0,1,0,2,1,0,0,0,0,1,1,0],"10.1016/s0735-1097(00)01054-8"],[11713447,"Safety and outcomes of thrombolysis with tissue plasminogen activator for treatment of intravascular thrombosis in children.","J Pediatr",2001,"Gupta et al.",5,[0],[15.77],15.77,9,9,7,[2,1,1,0,0,1,1,1,0,0,0,0,1,0,1,0],"10.1067/mpd.2001.118428"],[11932665,"Intravascular ultrasound scan evaluation of the obstructed vein.","J Vasc Surg",2002,"Neglén et al.",7,[0],[15.77],15.77,9,9,7,[1,1,1,2,1,0,1,0,0,0,0,0,0,1,0,1],"10.1067/mva.2002.121127"],[15159471,"Detection of electrographic seizures with continuous EEG monitoring in critically ill patients.","Neurology",2004,"Claassen et al.",5,[5],[13.28],15.77,9,9,7,[0,1,1,2,0,0,0,0,0,0,1,0,1,1,1,1],"10.1212/01.wnl.0000125184.88797.62"],[15630027,"Cardiovascular magnetic resonance in cardiac amyloidosis.","Circulation",2005,"Maceira et al.",3,[0,7],[13.28,1.0],15.77,15,9,7,[1,0,0,1,1,1,2,0,1,1,1,0,0,0,0,0],"10.1161/01.CIR.0000152819.97857.9D"],[15710984,"Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn's disease.","Gut",2005,"Costa et al.",7,[4],[15.77],15.77,11,9,7,[1,0,0,1,0,0,1,2,2,0,0,0,1,2,1,0],"10.1136/gut.2004.043406"],[16202350,"A randomised controlled trial and cost-effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in people aged 65 and over. The SAFE study.","Health Technol Assess",2005,"Hobbs et al.",2,[0],[15.77],15.77,13,9,7,[1,1,0,1,0,2,0,1,0,2,0,1,0,3,0,0],"10.3310/hta9400"],[16611192,"Safety and efficacy of lamivudine in patients with severe acute or fulminant hepatitis B, a multicenter experience.","J Viral Hepat",2006,"Tillmann et al.",3,[4,2],[15.77,15.12],15.77,12,9,7,[0,2,1,1,0,3,0,1,1,0,1,0,0,0,1,0],"10.1111/j.1365-2893.2005.00695.x"],[16739208,"Population-based assessment of adverse events associated with long-term glucocorticoid use.","Arthritis Rheum",2006,"Curtis et al.",7,[13,15],[3.74,0.0],15.77,15,9,8,[0,1,0,0,1,0,1,0,1,1,2,0,2,2,0,0],"10.1002/art.21984"],[17258378,"Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest.","Resuscitation",2007,"Sunde et al.",5,[0],[15.77],15.77,14,11,6,[1,1,2,1,4,0,0,0,1,0,1,0,0,0,1,0],"10.1016/j.resuscitation.2006.08.016"],[17457165,"Is the increasing rate of local excision for stage I rectal cancer in the United States justified?: a nationwide cohort study from the National Cancer Database.","Ann Surg",2007,"You et al.",5,[1,4],[15.77,15.77],15.77,12,9,9,[0,1,2,0,1,1,1,1,1,1,0,0,0,0,0,0],"10.1097/01.sla.0000252590.95116.4f"],[18760140,"Angiotensin inhibition in renovascular disease: a population-based cohort study.","Am Heart J",2008,"Hackam et al.",5,[0],[15.77],15.77,10,9,7,[1,1,0,0,0,0,0,2,1,0,1,0,0,2,1,1],"10.1016/j.ahj.2008.05.013"],[19405003,"Development and validation of a composite disease activity score for juvenile idiopathic arthritis.","Arthritis Rheum",2009,"Consolaro et al.",5,[11],[13.28],15.77,11,9,7,[0,1,0,0,0,0,1,1,1,1,0,1,0,0,1,2],"10.1002/art.24516"],[19520246,"Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management.","J Am Coll Cardiol",2009,"Yeh et al.",6,[0],[10.26],15.77,9,9,7,[1,0,1,1,0,1,0,0,0,1,0,1,2,0,0,1],"10.1016/j.jacc.2009.02.050"],[19821388,"Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis.","Cochrane Database Syst Rev",2009,"Hurkmans et al.",0,[11],[15.77],15.77,9,9,7,[2,1,0,0,0,0,1,1,0,0,1,1,0,1,0,1],"10.1002/14651858.CD006853.pub2"],[20004617,"Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study.","Lancet Oncol",2010,"Wolchok et al.",2,[1,14],[15.77,7.97],15.77,9,9,7,[0,0,1,0,0,1,1,1,2,0,1,1,0,1,0,0],"10.1016/S1470-2045(09)70334-1"],[20110121,"Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study.","Lancet",2010,"Currie et al.",5,[7],[8.47],15.77,13,9,7,[1,1,1,0,0,1,0,0,1,2,0,2,0,1,0,0],"10.1016/S0140-6736(09)61969-3"],[20647170,"OnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 1 trial.","Cephalalgia",2010,"Aurora et 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controlled clinical trial.","Lancet",2013,"Heidegger et al.",2,[2],[6.77],15.77,11,9,7,[0,0,0,2,0,2,1,0,2,0,1,0,1,1,1,0],"10.1016/S0140-6736(12)61351-8"],[25366685,"Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation.","J Clin Oncol",2015,"Kaufman et al.",3,[1],[15.77],15.77,12,9,7,[0,0,0,0,0,0,2,2,1,2,1,0,1,2,1,0],"10.1200/JCO.2014.56.2728"],[25581257,"The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop.","Ann Intern Med",2015,"Chou et al.",1,[6,0,13],[6.16,1.0,1.0],15.77,10,9,7,[0,0,0,0,0,3,1,0,0,0,1,1,1,1,1,1],"10.7326/M14-2559"],[36695182,"Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.","Circulation",2023,"Tsao et al.",6,[0,5,3],[15.77,8.01,1.0],15.77,20,17,6,[0,0,0,0,0,0,0,0,0,0,0,0,1,9,5,2],"10.1161/CIR.0000000000001123"],[12917299,"Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism.","N Engl J Med",2003,"Kearon et al.",2,[0,3],[15.76,10.16],15.76,10,10,8,[3,3,2,0,0,1,0,0,0,1,0,0,0,0,0,0],"10.1056/NEJMoa035422"],[15937763,"Risk factors for invasive aspergillosis in solid-organ transplant recipients: a case-control study.","Clin Infect Dis",2005,"Gavalda et al.",5,[2],[10.43],15.76,10,10,8,[3,0,0,0,0,3,0,0,1,0,0,0,0,1,2,0],"10.1086/430602"],[24029165,"Electronic cigarettes for smoking cessation: a randomised controlled trial.","Lancet",2013,"Bullen et al.",2,[6],[3.1],15.76,14,10,8,[0,0,0,1,4,3,0,0,0,0,2,0,0,0,1,0],"10.1016/S0140-6736(13)61842-5"],[25788234,"5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomised controlled trial.","Lancet",2015,"Mack et al.",2,[0],[15.76],15.76,22,10,10,[0,0,0,0,0,0,5,0,3,0,2,1,0,2,0,0],"10.1016/S0140-6736(15)60308-7"],[32468955,"Intracranial Efficacy and Survival With Tucatinib Plus Trastuzumab and Capecitabine for Previously Treated HER2-Positive Breast Cancer With Brain Metastases in the HER2CLIMB Trial.","J Clin Oncol",2020,"Lin et al.",2,[1,5],[15.76,7.75],15.76,11,10,8,[0,0,0,0,0,0,0,0,0,1,2,3,1,4,0,0],"10.1200/JCO.20.00775"],[34587385,"Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.","N Engl J Med",2021,"Sandborn et al.",2,[4],[15.76],15.76,11,10,9,[0,0,0,0,0,0,0,0,0,0,0,1,2,2,5,1],"10.1056/NEJMoa2033617"],[30865796,"Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol.","N Engl J Med",2019,"Ray et al.",2,[7],[8.01],15.72,16,12,8,[0,0,0,0,0,0,0,0,1,1,0,1,1,3,3,2],"10.1056/NEJMoa1803917"],[12667024,"Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy.","Ann Intern Med",2003,"Berl et 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al.",2,[0,7],[12.16,7.48],15.63,10,10,7,[0,0,0,0,0,3,0,2,1,0,0,0,0,2,1,1],"10.1016/j.jacc.2005.01.015"],[18490077,"The HEP-NET B/C co-infection trial: A prospective multicenter study to investigate the efficacy of pegylated interferon-alpha2b and ribavirin in patients with HBV/HCV co-infection.","J Hepatol",2008,"Potthoff et al.",3,[2,4],[15.63,15.63],15.63,13,10,7,[1,3,1,3,0,3,0,2,0,0,0,0,0,0,0,0],"10.1016/j.jhep.2008.03.028"],[29590544,"Duration of Adjuvant Chemotherapy for Stage III Colon Cancer.","N Engl J Med",2018,"Grothey et al.",2,[1,4],[15.63,14.84],15.63,11,10,8,[0,0,0,0,0,0,0,0,1,4,1,2,0,1,2,0],"10.1056/NEJMoa1713709"],[15451583,"In-water resuscitation--is it worthwhile?","Resuscitation",2004,"Szpilman et al.",5,[13],[6.16],15.62,12,10,6,[0,1,0,0,2,1,0,1,1,0,0,0,0,2,2,2],"10.1016/j.resuscitation.2004.03.017"],[18048817,"Is there a role for pelvic irradiation in localized prostate adenocarcinoma? 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Definitions, mechanisms, relevant outcomes, and clinical trial coordination.","Am J Respir Crit Care Med",1994,"Bernard et al.",4,[3],[10.26],15.56,11,8,7,[1,1,1,0,1,1,1,1,1,0,0,0,0,0,1,0],"10.1164/ajrccm.149.3.7509706"],[8637515,"Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses.","N Engl J Med",1996,"Pijls et al.",7,[0],[15.56],15.56,19,10,6,[2,3,1,3,1,0,1,1,1,0,0,1,0,0,0,0],"10.1056/NEJM199606273342604"],[10201454,"A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain.","Am J Gastroenterol",1999,"Gress et al.",2,[4],[15.56],15.56,9,8,7,[0,1,1,0,1,1,0,1,0,1,0,1,0,1,1,0],"10.1111/j.1572-0241.1999.01042.x"],[10235151,"Natural history of progression after PSA elevation following radical prostatectomy.","JAMA",1999,"Pound et al.",5,[1,8,9],[15.56,15.56,15.56],15.56,10,8,7,[0,0,1,1,0,1,1,1,1,0,0,0,1,1,0,1],"10.1001/jama.281.17.1591"],[11293640,"Broad-spectrum antibiotics for preterm, prelabour rupture of fetal membranes: the ORACLE I randomised trial. 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al.",2,[3],[15.56],15.56,10,8,8,[1,0,1,0,1,1,0,1,0,0,2,1,1,0,1,0],"10.1164/rccm.200412-1756OC"],[15983290,"Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).","Arch Intern Med",2005,"Whelton et al.",2,[7,0],[7.97,11.84],15.56,15,8,7,[1,0,3,1,0,0,0,1,1,0,0,1,0,1,1,1],"10.1001/archinte.165.12.1401"],[16463425,"Repetitive 18F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a prospective study of 35 patients.","Arthritis Rheum",2006,"Blockmans et al.",3,[0,5,11],[11.84,6.77,6.77],15.56,11,8,7,[0,0,1,1,0,1,0,0,0,0,1,1,1,1,1,1],"10.1002/art.21699"],[16782910,"Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402.","J Clin Oncol",2006,"Cairncross et 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individual patient data from 16 randomized controlled trials.","J Clin Oncol",2008,"NSCLC Meta-Analyses Collaborative Group",0,[1,3],[15.56,15.56],15.56,10,8,8,[1,1,1,1,1,0,0,1,1,0,0,1,2,0,0,0],"10.1200/JCO.2008.17.7162"],[19053049,"Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial.","Hepatology",2009,"Harrison et al.",2,[4,7],[15.56,7.22],15.56,13,8,8,[0,1,1,1,0,1,0,0,1,1,0,1,0,1,0,1],"10.1002/hep.22575"],[19758907,"The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease.","EuroIntervention",2005,"Sianos et al.",7,[0],[15.56],15.56,16,10,8,[2,1,2,1,1,0,0,0,2,0,1,1,0,1,0,0],""],[19853892,"Home treatment in pulmonary embolism.","Thromb Res",2010,"Otero et al.",2,[0,3],[15.56,10.68],15.56,10,8,7,[0,1,0,1,1,1,0,1,1,1,2,0,0,0,0,1],"10.1016/j.thromres.2009.09.026"],[20028993,"Risks of Lynch syndrome cancers for MSH6 mutation carriers.","J Natl Cancer Inst",2010,"Baglietto et al.",7,[1,4,7],[15.56,13.46,11.84],15.56,13,8,10,[0,1,1,1,2,0,0,0,1,1,0,0,1,1,0,1],"10.1093/jnci/djp473"],[21131037,"First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): a randomised controlled trial.","Lancet",2010,"Morgan et al.",2,[1,0,10],[13.08,11.04,11.04],15.56,12,8,7,[1,0,0,2,3,0,1,1,1,1,0,1,1,0,0,0],"10.1016/S0140-6736(10)62051-X"],[21412903,"Celiac plexus block for pancreatic cancer pain in adults.","Cochrane Database Syst Rev",2011,"Arcidiacono et al.",0,[1,4,7],[12.24,7.97,2.69],15.56,11,8,7,[0,1,1,0,0,2,0,2,1,0,1,1,0,1,1,0],"10.1002/14651858.CD007519.pub2"],[21844495,"Carboplatin plus paclitaxel versus carboplatin plus pegylated liposomal doxorubicin as first-line treatment for patients with ovarian cancer: the MITO-2 randomized phase III trial.","J Clin Oncol",2011,"Pignata et al.",2,[1,7,9],[15.56,15.56,15.56],15.56,9,8,7,[0,0,1,1,0,0,0,1,1,0,1,1,1,1,1,0],"10.1200/JCO.2010.33.8566"],[22052532,"FRAX underestimates fracture risk in patients with diabetes.","J Bone Miner Res",2012,"Giangregorio et al.",7,[7,13],[15.56,15.56],15.56,10,8,7,[0,0,1,0,1,0,0,0,1,1,1,1,1,2,1,0],"10.1002/jbmr.556"],[22056247,"Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.","Lancet",2011,"Rini et al.",2,[1,8],[13.46,13.46],15.56,14,8,7,[0,1,1,2,0,3,1,3,1,1,0,1,0,0,0,0],"10.1016/S0140-6736(11)61613-9"],[22179532,"Six-month versus 12-month dual antiplatelet therapy after implantation of drug-eluting stents: the Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting (EXCELLENT) randomized, multicenter study.","Circulation",2012,"Gwon et al.",2,[0],[15.56],15.56,21,14,6,[0,1,1,3,2,3,1,2,0,0,0,0,1,1,0,0],"10.1161/CIRCULATIONAHA.111.059022"],[22203767,"Summary report on the graded prognostic assessment: an accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases.","J Clin Oncol",2012,"Sperduto et al.",5,[1,5],[15.56,12.24],15.56,14,8,8,[0,0,0,1,1,2,0,2,1,1,0,2,0,2,2,0],"10.1200/JCO.2011.38.0527"],[22503995,"Endoscopic skipping of the distal terminal ileum in Crohn's disease can lead to negative results from ileocolonoscopy.","Clin Gastroenterol Hepatol",2012,"Samuel et al.",7,[4],[15.56],15.56,9,8,7,[0,0,0,0,1,0,0,1,1,1,1,1,1,1,1,0],"10.1016/j.cgh.2012.03.026"],[24120480,"Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial.","Lancet Oncol",2013,"Nordlinger et al.",2,[1,4],[15.56,15.56],15.56,11,8,7,[0,0,0,1,0,0,1,0,1,2,1,1,1,1,2,0],"10.1016/S1470-2045(13)70447-9"],[24201688,"Accuracy of ultrasonography at 11-14 weeks of gestation for detection of fetal structural anomalies: a systematic review.","Obstet Gynecol",2013,"Rossi et al.",1,[17],[10.68],15.56,10,8,7,[0,0,0,0,0,1,1,1,0,1,1,1,0,1,1,1],"10.1097/AOG.0000000000000015"],[22706835,"Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.","JAMA",2012,"Devereaux et al.",5,[0],[15.54],15.54,20,11,7,[0,1,0,3,2,1,1,0,0,0,0,0,3,2,0,0],"10.1001/jama.2012.5502"],[23635669,"Long-term mortality associated with oophorectomy compared with ovarian conservation in the nurses' health study.","Obstet Gynecol",2013,"Parker et al.",5,[0],[1.0],15.54,11,11,6,[0,0,0,0,1,1,0,4,2,0,1,1,0,1,0,0],"10.1097/AOG.0b013e3182864350"],[16820547,"Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial.","JAMA",2006,"Jorenby et al.",2,[0],[6.54],15.51,20,12,6,[4,3,2,1,1,1,0,0,0,0,0,0,0,0,2,0],"10.1001/jama.296.1.56"],[20513595,"A risk score to predict bleeding in patients with acute coronary 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candidiasis-related death in allogeneic marrow transplant recipients: long-term follow-up of a randomized, placebo-controlled trial.","Blood",2000,"Marr et al.",2,[2],[14.63],15.45,14,9,7,[3,4,1,0,0,1,0,0,0,0,1,0,1,1,0,0],""],[11134220,"Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropenia.","J Clin Oncol",2001,"Caillot et al.",7,[2,10,1],[14.06,2.69,4.65],15.45,10,9,7,[2,1,0,2,1,1,0,0,1,0,1,0,0,0,0,0],"10.1200/JCO.2001.19.1.253"],[12767102,"Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials.","Cancer",2003,"Swain et al.",2,[0],[9.17],15.45,9,9,7,[0,0,1,0,1,3,1,0,1,0,0,0,1,0,0,1],"10.1002/cncr.11407"],[14514341,"Prevalence and natural history of adrenal incidentalomas.","Eur J Endocrinol",2003,"Barzon et al.",6,[1,7],[12.16,15.45],15.45,10,9,7,[1,0,0,0,0,3,2,1,0,1,0,0,1,0,1,0],"10.1530/eje.0.1490273"],[14613288,"Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis: a randomized, controlled trial.","Arthritis Rheum",2003,"Davis et al.",2,[11,13],[13.47,13.47],15.45,12,9,7,[1,3,1,1,1,0,3,0,2,0,0,0,0,0,0,0],"10.1002/art.11325"],[14707568,"Effect of neuromuscular blocking agents on gas exchange in patients presenting with acute respiratory distress syndrome.","Crit Care Med",2004,"Gainnier et al.",2,[3],[14.63],15.45,10,9,8,[0,0,0,0,0,2,1,0,1,2,0,1,0,1,0,1],"10.1097/01.CCM.0000104114.72614.BC"],[14722147,"Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals.","JAMA",2004,"Greenland et al.",5,[0,7],[12.95,6.77],15.45,9,9,7,[2,2,1,1,1,0,1,1,0,0,0,0,0,0,0,0],"10.1001/jama.291.2.210"],[15593207,"Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial.","Arthritis Rheum",2004,"Houssiau et 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al.",2,[0,3],[15.45,12.95],15.45,13,9,7,[0,0,0,1,0,1,1,0,3,2,2,0,0,0,0,1],"10.1016/j.amjcard.2012.09.027"],[23500312,"Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front (STOP AF) pivotal trial.","J Am Coll Cardiol",2013,"Packer et al.",2,[0],[15.45],15.45,15,9,7,[0,1,0,2,1,1,0,1,0,0,0,0,0,4,1,0],"10.1016/j.jacc.2012.11.064"],[23644079,"Early administration of azathioprine vs conventional management of Crohn's Disease: a randomized controlled trial.","Gastroenterology",2013,"Cosnes et al.",2,[4],[15.45],15.45,10,9,7,[0,0,0,3,0,0,0,2,1,1,1,0,0,1,1,0],"10.1053/j.gastro.2013.04.048"],[23749611,"Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force.","Ann Rheum Dis",2014,"Smolen et al.",1,[11,13,14],[15.45,13.27,7.22],15.45,11,9,7,[0,0,0,2,1,3,1,1,0,1,0,0,0,0,0,1],"10.1136/annrheumdis-2013-203419"],[24291113,"Novel insight into the natural history of short QT syndrome.","J Am Coll Cardiol",2014,"Mazzanti et al.",7,[0],[15.45],15.45,11,9,7,[0,0,0,0,1,1,0,1,1,0,2,0,0,2,0,1],"10.1016/j.jacc.2013.09.078"],[24572077,"4 Gy versus 24 Gy radiotherapy for patients with indolent lymphoma (FORT): a randomised phase 3 non-inferiority trial.","Lancet Oncol",2014,"Hoskin et al.",2,[10,1],[15.45,13.47],15.45,11,9,7,[0,0,0,1,1,2,0,0,0,3,2,0,0,1,0,1],"10.1016/S1470-2045(14)70036-1"],[25417114,"Integrated genomic characterization of papillary thyroid carcinoma.","Cell",2014,"Cancer Genome Atlas Research Network",7,[1,7],[12.95,14.06],15.45,10,9,7,[0,0,0,0,0,2,1,0,1,1,1,0,0,1,3,0],"10.1016/j.cell.2014.09.050"],[25448873,"Quality indicators for colonoscopy.","Am J Gastroenterol",2015,"Rex et al.",7,[1,4],[12.95,12.95],15.45,18,11,6,[0,0,0,0,0,1,2,0,0,1,2,3,0,1,1,0],"10.1038/ajg.2014.385"],[25863654,"Induction of labour versus expectant management for large-for-date fetuses: a randomised controlled trial.","Lancet",2015,"Boulvain 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al.",5,[1,4,7],[15.45,10.26,10.26],15.45,10,9,7,[0,0,0,0,0,0,0,0,1,1,1,3,0,1,2,1],"10.1001/jama.2018.6228"],[30824296,"A 16-yr Follow-up of the European Randomized study of Screening for Prostate Cancer.","Eur Urol",2019,"Hugosson et al.",2,[1,8,9],[15.45,15.45,15.45],15.45,11,9,7,[0,0,0,0,0,0,0,0,1,1,1,1,2,4,0,1],"10.1016/j.eururo.2019.02.009"],[30883057,"Coronary Angiography after Cardiac Arrest without ST-Segment Elevation.","N Engl J Med",2019,"Lemkes et al.",2,[0],[15.45],15.45,14,11,6,[0,0,0,0,0,0,0,0,0,2,2,0,0,2,5,1],"10.1056/NEJMoa1816897"],[31542292,"Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial.","Lancet",2019,"Matthews et al.",2,[7],[13.47],15.45,11,9,7,[0,0,0,0,0,0,0,0,0,1,1,1,1,4,1,1],"10.1016/S0140-6736(19)32131-2"],[14525770,"Itraconazole versus fluconazole for prevention of fungal infections in 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I. Prevalence, impact of medications and disparities in health care.","World Psychiatry",2011,"DE Hert et al.",7,[6],[12.76],15.25,9,9,7,[0,1,1,0,1,3,1,0,0,1,0,0,1,0,0,0],"10.1002/j.2051-5545.2011.tb00014.x"],[21556040,"The multi-dimensional burden of cirrhosis and hepatic encephalopathy on patients and caregivers.","Am J Gastroenterol",2011,"Bajaj et al.",5,[4,5,7],[15.25,5.78,5.78],15.25,10,9,7,[0,0,0,1,1,1,0,0,1,1,2,0,0,0,0,2],"10.1038/ajg.2011.157"],[22042885,"Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands.","Circulation",2011,"Sy et al.",5,[0,17],[15.25,1.0],15.25,11,9,7,[0,0,0,1,0,0,1,1,0,0,1,1,1,3,0,0],"10.1161/CIRCULATIONAHA.111.028258"],[22071812,"Preoperative hair removal to reduce surgical site infection.","Cochrane Database Syst Rev",2011,"Tanner et al.",0,[2],[6.2],15.25,10,9,7,[0,1,1,1,0,0,0,1,3,2,1,0,0,0,0,0],"10.1002/14651858.CD004122.pub4"],[23239837,"Heart disease and stroke statistics--2013 update: a report from the American Heart Association.","Circulation",2013,"Go et al.",6,[0,5],[10.92,1.0],15.25,17,12,7,[0,0,2,4,4,0,0,0,0,0,1,1,0,0,0,0],"10.1161/CIR.0b013e31828124ad"],[23711182,"The presence of a cytopathologist increases the diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration cytology for pancreatic adenocarcinoma: a meta-analysis.","Cytopathology",2013,"Hébert-Magee et al.",0,[1,4,7],[15.25,15.25,15.25],15.25,10,9,8,[0,0,0,1,0,1,2,0,0,0,1,0,1,2,1,0],"10.1111/cyt.12071"],[24055383,"Development and evaluation of the universal ACS NSQIP surgical risk calculator: a decision aid and informed consent tool for patients and surgeons.","J Am Coll Surg",2013,"Bilimoria et al.",7,[0],[11.31],15.25,14,9,7,[0,0,0,1,1,0,2,2,0,1,0,0,1,2,0,0],"10.1016/j.jamcollsurg.2013.07.385"],[24177257,"Three vs twelve months of dual antiplatelet therapy after zotarolimus-eluting stents: the OPTIMIZE randomized trial.","JAMA",2013,"Feres et al.",2,[0],[15.25],15.25,24,13,5,[0,0,0,3,1,5,2,1,1,0,0,0,1,1,0,0],"10.1001/jama.2013.282183"],[25691262,"Altered dietary salt intake for people with chronic kidney disease.","Cochrane Database Syst Rev",2015,"McMahon et al.",0,[8],[10.87],15.25,10,9,7,[0,0,0,0,1,0,0,1,1,2,3,1,0,0,1,0],"10.1002/14651858.CD010070.pub2"],[26224076,"Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction.","Eur Heart J",2015,"González-López et al.",5,[0,7,5],[14.06,7.97,2.69],15.25,11,9,7,[0,0,0,0,0,1,0,0,0,1,0,2,1,1,2,1],"10.1093/eurheartj/ehv338"],[27774838,"Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.","N Engl J Med",2017,"Myles et al.",2,[0,5],[14.06,1.0],15.25,12,9,8,[0,0,0,0,0,0,0,2,1,1,2,0,1,1,2,0],"10.1056/NEJMoa1606424"],[29989857,"Patient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology-RTOG 1203.","J Clin Oncol",2018,"Klopp et al.",2,[9,1,13],[15.25,13.28,4.04],15.25,13,9,7,[0,0,0,0,0,0,0,0,0,1,1,3,1,1,2,2],"10.1200/JCO.2017.77.4273"],[19815268,"Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial.","Lancet",2009,"Comi et al.",2,[5],[15.24],15.24,9,9,9,[0,3,4,1,0,0,0,1,0,0,0,0,0,0,0,0],"10.1016/S0140-6736(09)61259-9"],[21800002,"Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis.","Thromb Haemost",2011,"Dentali et al.",0,[0,10],[11.85,0.0],15.24,10,9,10,[0,0,1,0,2,1,0,5,0,0,0,0,0,0,0,0],"10.1160/TH11-01-0052"],[27253694,"Cancer treatment and survivorship statistics, 2016.","CA Cancer J Clin",2016,"Miller et al.",7,[1],[12.39],15.24,9,9,9,[0,0,0,0,0,0,3,2,3,0,0,0,0,0,1,0],"10.3322/caac.21349"],[27458945,"Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases: A Randomized Clinical Trial.","JAMA",2016,"Brown et al.",2,[1,5,6],[15.24,11.85,0.0],15.24,9,9,9,[0,0,0,0,0,0,0,2,0,0,0,3,0,2,2,0],"10.1001/jama.2016.9839"],[29463627,"Spironolactone Versus Clonidine as a Fourth-Drug Therapy for Resistant Hypertension: The ReHOT Randomized Study (Resistant Hypertension Optimal Treatment).","Hypertension",2018,"Krieger et al.",2,[0],[13.55],15.24,11,9,9,[0,0,0,0,0,0,0,0,0,2,0,0,0,3,3,1],"10.1161/HYPERTENSIONAHA.117.10662"],[30910320,"β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.","Lancet",2019,"Villanueva et al.",2,[4],[12.39],15.24,12,11,8,[0,0,0,0,0,0,0,0,0,0,3,0,0,4,3,1],"10.1016/S0140-6736(18)31875-0"],[31684684,"Antiplatelet agents for preventing pre-eclampsia and its complications.","Cochrane Database Syst Rev",2019,"Duley et al.",0,[9],[11.85],15.24,11,9,8,[0,0,0,0,0,0,0,0,0,0,0,2,2,4,0,2],"10.1002/14651858.CD004659.pub3"],[32563378,"Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.","Lancet",2020,"HALT-IT Trial Collaborators",2,[0,4],[9.3,7.75],15.24,9,9,9,[0,0,0,0,0,0,0,0,0,0,3,1,1,0,4,0],"10.1016/S0140-6736(20)30848-5"],[33390044,"Adherence to Single-Pill Versus Free-Equivalent Combination Therapy in Hypertension: A Systematic Review and Meta-Analysis.","Hypertension",2021,"Parati et al.",0,[0],[15.24],15.24,15,9,10,[0,0,0,0,0,0,0,0,0,0,0,1,0,2,5,2],"10.1161/HYPERTENSIONAHA.120.15781"],[34170647,"Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.","N Engl J Med",2021,"Frías et al.",2,[7],[13.55],15.24,10,9,9,[0,0,0,0,0,0,0,0,0,0,0,1,0,4,2,2],"10.1056/NEJMoa2107519"],[37142273,"Nicotine receptor partial agonists for smoking cessation.","Cochrane Database Syst Rev",2023,"Livingstone-Banks et al.",1,[0],[7.75],15.24,11,9,9,[0,0,0,0,0,0,0,0,0,0,0,0,1,3,4,2],"10.1002/14651858.CD006103.pub8"],[38279402,"Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial.","Lancet Rheumatol",2021,"Ebata et al.",7,[11,3],[12.39,11.85],15.24,11,9,9,[0,0,0,0,0,0,0,0,0,0,0,0,1,4,1,3],"10.1016/S2665-9913(21)00107-7"],[36214590,"Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death.","N Engl J Med",2022,"Bretthauer et al.",2,[1,4],[15.23,13.68],15.23,11,11,9,[0,0,0,0,0,0,0,0,0,0,0,0,2,4,5,0],"10.1056/NEJMoa2208375"],[36927642,"EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update.","Ann Rheum Dis",2024,"Hellmich et al.",1,[11,0,14],[9.19,9.94,7.29],15.23,11,11,9,[0,0,0,0,0,0,0,0,0,0,0,0,0,2,7,2],"10.1136/ard-2022-223764"],[37075781,"Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet",2023,"Kelley et al.",2,[1,4],[15.23,15.23],15.23,11,11,9,[0,0,0,0,0,0,0,0,0,0,0,0,2,5,4,0],"10.1016/S0140-6736(23)00727-4"],[19556262,"Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.","Eur Heart J",2009,"Frustaci et al.",2,[0],[13.18],15.22,11,10,6,[0,1,2,0,0,2,1,0,0,0,0,1,1,0,1,1],"10.1093/eurheartj/ehp249"],[21704808,"Use of antimicrobials for EUS-guided FNA of pancreatic cysts: a retrospective, comparative analysis.","Gastrointest Endosc",2011,"Guarner-Argente et al.",5,[2],[3.1],15.22,20,10,7,[0,0,1,1,1,2,1,2,0,0,2,0,0,0,1,0],"10.1016/j.gie.2011.03.1244"],[11809180,"Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial.","Lancet",2002,"Chan et al.",2,[2,4],[13.08,9.53],15.2,11,9,7,[0,1,1,1,0,1,2,0,0,2,1,0,0,1,0,1],"10.1016/s0140-6736(02)07272-0"],[22149876,"Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.","N Engl J Med",2012,"Baselga et al.",2,[1],[15.2],15.2,10,9,6,[0,2,1,1,0,1,1,0,0,1,1,0,1,0,0,1],"10.1056/NEJMoa1109653"],[8420741,"Esophageal eosinophilia with dysphagia. A distinct clinicopathologic syndrome.","Dig Dis Sci",1993,"Attwood et al.",5,[4,10,16],[15.19,13.38,0.0],15.19,9,9,8,[0,0,1,0,0,0,0,2,0,1,0,0,0,3,2,0],"10.1007/BF01296781"],[10188721,"Cancer risk in mutation carriers of DNA-mismatch-repair genes.","Int J Cancer",1999,"Aarnio et al.",7,[1,4,7],[15.19,13.38,10.16],15.19,12,9,11,[0,0,3,2,2,0,0,0,0,0,0,0,0,1,0,1],"10.1002/(sici)1097-0215(19990412)81:2<214::aid-ijc8>3.0.co;2-l"],[11445689,"Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).","Crit Care Med",2001,"Ely et al.",5,[6,5],[11.58,9.77],15.19,10,9,8,[0,0,3,0,1,0,0,1,0,3,0,0,0,0,1,0],"10.1097/00003246-200107000-00012"],[11680442,"Blood transfusion in elderly patients with acute myocardial infarction.","N Engl J Med",2001,"Wu et al.",5,[0,10],[7.75,6.73],15.19,10,9,8,[1,2,4,0,1,0,0,0,0,0,0,1,0,0,0,0],"10.1056/NEJMoa010615"],[14762776,"Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease.","Gastroenterology",2004,"Rutgeerts et al.",2,[4],[15.19],15.19,9,9,8,[0,1,3,1,0,0,3,1,0,0,0,0,0,0,0,0],"10.1053/j.gastro.2003.11.014"],[14988816,"Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases.","Gastroenterology",2004,"Pennazio et al.",3,[4],[13.38],15.19,9,9,8,[2,0,0,0,3,0,2,0,0,0,0,0,1,0,0,1],"10.1053/j.gastro.2003.11.057"],[15095217,"Management of central venous catheters in patients with cancer and candidemia.","Clin Infect Dis",2004,"Raad et al.",5,[2,1],[15.19,4.65],15.19,10,9,8,[3,0,1,2,0,0,2,0,0,0,0,0,0,0,0,1],"10.1086/382874"],[15229957,"Pneumococcal vaccine response in psoriatic arthritis patients during treatment with etanercept.","J Rheumatol",2004,"Mease et al.",2,[11,13,14],[13.38,0.0,0.0],15.19,10,9,8,[4,0,0,1,1,2,0,0,1,0,0,0,0,0,0,0],""],[15561393,"Opioids in chronic non-cancer pain: systematic review of efficacy and safety.","Pain",2004,"Kalso et al.",1,[6],[7.47],15.19,10,9,8,[0,3,0,2,0,0,2,0,1,0,0,0,1,0,0,0],"10.1016/j.pain.2004.09.019"],[15572716,"Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs.","JAMA",2004,"Graham et al.",7,[13],[3.1],15.19,10,9,8,[0,3,0,4,0,1,0,0,1,0,0,1,0,0,0,0],"10.1001/jama.292.21.2585"],[15900257,"Thrombosis risk assessment as a guide to quality patient care.","Dis Mon",2005,"Caprini",6,[0,3],[13.38,1.0],15.19,10,9,8,[0,1,0,0,2,0,2,3,0,1,0,0,0,0,0,0],"10.1016/j.disamonth.2005.02.003"],[16619154,"Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis.","Clin Infect Dis",2006,"Pfeiffer et al.",0,[2],[11.58],15.19,10,9,8,[3,2,0,0,1,2,0,0,0,0,0,0,0,0,1,0],"10.1086/503427"],[16799972,"Elevated levels of von Willebrand Factor in cirrhosis support platelet adhesion despite reduced functional capacity.","Hepatology",2006,"Lisman et al.",7,[4],[15.19],15.19,10,9,8,[0,0,0,0,0,0,0,0,2,1,2,0,0,3,2,0],"10.1002/hep.21231"],[16950994,"Use and efficacy of endotracheal versus intravenous epinephrine during neonatal cardiopulmonary resuscitation in the delivery room.","Pediatrics",2006,"Barber et al.",5,[13],[0.0],15.19,12,11,7,[2,0,0,0,3,0,1,0,0,0,0,0,0,0,4,1],"10.1542/peds.2006-0416"],[17015527,"Prevalence of fatty liver in children and adolescents.","Pediatrics",2006,"Schwimmer et al.",5,[4],[8.47],15.19,11,9,8,[1,3,1,0,0,0,3,1,0,0,0,0,0,0,0,0],"10.1542/peds.2006-1212"],[17253452,"Enteral nutritional therapy for induction of remission in Crohn's disease.","Cochrane Database Syst Rev",2007,"Zachos et al.",0,[4],[15.19],15.19,9,9,8,[1,1,0,2,0,0,0,3,2,0,0,0,0,0,0,0],"10.1002/14651858.CD000542.pub2"],[17434094,"Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK).","Lancet Neurol",2007,"Gray et al.",2,[0,5,7],[13.38,13.38,4.65],15.19,9,9,8,[2,2,2,2,0,0,0,1,0,0,0,0,0,0,0,0],"10.1016/S1474-4422(07)70080-7"],[17984186,"Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia.","J Clin Oncol",2007,"Hillmen et al.",2,[1,10],[15.19,13.38],15.19,9,9,8,[3,3,1,0,0,0,1,1,0,0,0,0,0,0,0,0],"10.1200/JCO.2007.12.9098"],[18779187,"Diagnosis and management of work-related asthma: American College Of Chest Physicians Consensus Statement.","Chest",2008,"Tarlo et al.",1,[3,12],[14.44,12.63],15.19,10,9,8,[0,1,0,4,2,0,0,2,0,1,0,0,0,0,0,0],"10.1378/chest.08-0201"],[19124524,"Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors.","Ann Rheum Dis",2009,"Westhovens et al.",2,[11],[15.19],15.19,9,9,8,[2,1,2,3,0,0,0,0,0,0,0,0,1,0,0,0],"10.1136/ard.2008.101121"],[20040605,"Measuring the transition readiness of youth with special healthcare needs: validation of the TRAQ--Transition Readiness Assessment Questionnaire.","J Pediatr Psychol",2011,"Sawicki et al.",7,[],[],15.19,9,9,8,[0,0,0,0,0,1,4,1,0,0,0,0,0,2,0,1],"10.1093/jpepsy/jsp128"],[20170948,"Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial.","Lancet",2010,"Bakris et al.",2,[0,8],[9.17,2.69],15.19,11,9,8,[0,0,2,1,0,2,0,0,3,0,0,0,0,1,0,0],"10.1016/S0140-6736(09)62100-0"],[20547982,"Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.","J Clin Oncol",2010,"Ladenstein et al.",3,[1],[15.19],15.19,10,9,8,[0,1,0,1,0,0,0,0,0,0,0,0,0,2,5,1],"10.1200/JCO.2009.22.9864"],[22760290,"Association between vaccination for herpes zoster and risk of herpes zoster infection among older patients with selected immune-mediated diseases.","JAMA",2012,"Zhang et al.",5,[2],[4.04],15.19,11,9,8,[0,0,1,0,0,2,2,0,2,0,2,0,0,0,0,0],"10.1001/jama.2012.7304"],[23708639,"Vitamin D in the healthy European paediatric population.","J Pediatr Gastroenterol Nutr",2013,"Braegger et al.",6,[7],[9.02],15.19,9,9,8,[0,0,0,0,1,1,1,5,0,0,0,1,0,0,0,0],"10.1097/MPG.0b013e31828f3c05"],[23978719,"Hepatocellular cancer: the impact of obesity, type 2 diabetes and a multidisciplinary team.","J Hepatol",2014,"Dyson et al.",7,[7,4,1],[1.0,15.19,4.65],15.19,12,9,10,[0,0,0,0,0,2,0,0,1,0,1,3,0,2,0,0],"10.1016/j.jhep.2013.08.011"],[24275329,"A phenotypic analysis shows that eosinophilic esophagitis is a progressive fibrostenotic disease.","Gastrointest Endosc",2014,"Dellon et al.",5,[4,10,12],[15.19,15.19,15.19],15.19,9,9,8,[0,0,0,0,0,0,0,1,0,1,0,0,0,4,2,1],"10.1016/j.gie.2013.10.027"],[24528911,"Safety of dermatologic medications in pregnancy and lactation: Part I. Pregnancy.","J Am Acad Dermatol",2014,"Murase et al.",6,[17],[4.04],15.19,10,9,8,[0,0,0,0,0,3,0,0,3,0,1,0,0,2,1,0],"10.1016/j.jaad.2013.09.010"],[24846275,"Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials.","BMJ",2014,"Ford et al.",0,[2,4,1],[4.6,14.44,4.65],15.19,9,9,8,[0,0,0,0,2,0,4,0,1,0,0,0,0,1,1,0],"10.1136/bmj.g3174"],[25901427,"Prednisolone or pentoxifylline for alcoholic hepatitis.","N Engl J Med",2015,"Thursz et al.",2,[4],[15.19],15.19,10,9,8,[0,0,0,0,0,0,0,2,2,4,0,0,1,1,0,0],"10.1056/NEJMoa1412278"],[26374429,"Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.","J Natl Cancer Inst",2015,"Allegra et al.",2,[1,4],[15.19,15.19],15.19,10,9,8,[0,0,0,0,0,0,2,1,0,2,0,0,0,1,4,0],"10.1093/jnci/djv248"],[26567029,"Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis.","Gut",2017,"Ford et al.",0,[6],[2.69],15.19,9,9,8,[0,0,0,0,0,0,1,1,0,0,0,2,0,0,4,1],"10.1136/gutjnl-2015-310721"],[27028912,"Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol.","N Engl J Med",2016,"Hodis et al.",2,[0],[9.17],15.19,11,9,8,[0,0,0,0,0,0,2,1,0,1,3,0,0,3,0,0],"10.1056/NEJMoa1505241"],[27216274,"First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic leukaemia (CLL10): an international, open-label, randomised, phase 3, non-inferiority trial.","Lancet Oncol",2016,"Eichhorst et al.",2,[1,10],[15.19,15.19],15.19,9,9,8,[0,0,0,0,0,0,2,3,0,0,1,0,0,1,2,0],"10.1016/S1470-2045(16)30051-1"],[27411077,"An updated systematic review and meta-analysis on the association between Helicobacter pylori infection and iron deficiency anemia.","Helicobacter",2017,"Hudak et al.",0,[2,7,10],[10.83,4.65,4.65],15.19,10,9,9,[0,0,0,0,0,0,0,0,0,2,2,1,0,2,2,0],"10.1111/hel.12330"],[27547925,"Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection: A Randomized Trial.","Ann Intern Med",2016,"Kelly et al.",2,[2],[15.19],15.19,11,9,7,[0,0,0,0,0,0,0,2,0,1,3,0,0,2,0,1],"10.7326/M16-0271"],[28034064,"Impact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.","J Clin Oncol",2017,"Chun et al.",2,[1,3],[15.19,15.19],15.19,11,9,9,[0,0,0,0,0,0,1,0,0,0,0,2,1,2,4,0],"10.1200/JCO.2016.69.1378"],[28240687,"Liberal Versus Restrictive Transfusion Strategy in Critically Ill Oncologic Patients: The Transfusion Requirements in Critically Ill Oncologic Patients Randomized Controlled Trial.","Crit Care Med",2017,"Bergamin et al.",2,[1,2],[1.0,1.0],15.19,9,9,8,[0,0,0,0,0,0,0,1,2,2,0,0,1,0,3,0],"10.1097/CCM.0000000000002283"],[28455679,"Weight Loss and Improvement in Comorbidity: Differences at 5%, 10%, 15%, and Over.","Curr Obes Rep",2017,"Ryan et al.",6,[7],[13.38],15.19,11,9,9,[0,0,0,0,0,0,0,0,1,2,0,1,1,0,5,0],"10.1007/s13679-017-0262-y"],[28584032,"Safety of Sports for Athletes With Implantable Cardioverter-Defibrillators: Long-Term Results of a Prospective Multinational Registry.","Circulation",2017,"Lampert et al.",3,[0],[15.19],15.19,14,9,8,[0,0,0,0,0,0,0,0,2,1,3,0,0,4,1,0],"10.1161/CIRCULATIONAHA.117.027828"],[28774845,"Epidemiology and Natural History of Eosinophilic Esophagitis.","Gastroenterology",2018,"Dellon et al.",6,[4,10,12],[15.19,11.85,11.85],15.19,11,9,8,[0,0,0,0,0,0,0,1,0,1,0,1,0,2,4,0],"10.1053/j.gastro.2017.06.067"],[28859944,"Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.","Lancet",2017,"Townsend et al.",2,[0],[15.19],15.19,11,9,8,[0,0,0,0,0,0,0,2,1,1,0,0,0,4,1,0],"10.1016/S0140-6736(17)32281-X"],[28942782,"Eighth annual INTERMACS report: Special focus on framing the impact of adverse events.","J Heart Lung Transplant",2017,"Kirklin et al.",6,[0],[13.38],15.19,12,9,8,[0,0,0,0,0,0,0,0,2,2,2,1,0,3,0,0],"10.1016/j.healun.2017.07.005"],[29129575,"Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis.","Lancet Diabetes Endocrinol",2018,"Monticone et al.",0,[0,7],[13.38,4.65],15.19,12,9,8,[0,0,0,0,0,0,0,0,1,0,0,1,0,5,2,1],"10.1016/S2213-8587(17)30319-4"],[29154106,"Diagnostic criteria for idiopathic pulmonary fibrosis: a Fleischner Society White Paper.","Lancet Respir Med",2018,"Lynch et al.",4,[3],[15.19],15.19,11,9,9,[0,0,0,0,0,0,0,0,0,2,3,3,1,0,1,0],"10.1016/S2213-2600(17)30433-2"],[29360829,"Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis.","PLoS Med",2018,"Keag et al.",0,[9,3,8],[13.38,1.0,0.0],15.19,11,9,7,[0,0,0,0,0,0,0,3,0,1,0,0,0,2,3,1],"10.1371/journal.pmed.1002494"],[29914843,"Diagnostic accuracy of magnetic resonance enterography and small bowel ultrasound for the extent and activity of newly diagnosed and relapsed Crohn's disease (METRIC): a multicentre trial.","Lancet Gastroenterol Hepatol",2018,"Taylor et al.",2,[4],[15.19],15.19,9,9,8,[0,0,0,0,0,0,0,0,2,0,1,0,1,2,3,0],"10.1016/S2468-1253(18)30161-4"],[30060258,"Concepts and Controversies in Haemostasis and Thrombosis Associated with Liver Disease: Proceedings of the 7th International Coagulation in Liver Disease Conference.","Thromb Haemost",2018,"Intagliata et al.",7,[4,0],[12.55,2.0],15.19,9,9,8,[0,0,0,0,0,0,0,0,0,1,2,1,0,4,1,0],"10.1055/s-0038-1666861"],[30506586,"Vitamin E Improves Transplant-Free Survival and Hepatic Decompensation Among Patients With Nonalcoholic Steatohepatitis and Advanced Fibrosis.","Hepatology",2020,"Vilar-Gomez et al.",5,[4],[15.19],15.19,12,9,10,[0,0,0,0,0,0,0,0,0,1,3,2,0,1,2,0],"10.1002/hep.30368"],[30535100,"Seven Versus 14 Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia: A Noninferiority Randomized Controlled Trial.","Clin Infect Dis",2019,"Yahav et al.",2,[2],[13.38],15.19,10,9,9,[0,0,0,0,0,0,0,0,0,1,2,0,0,3,2,1],"10.1093/cid/ciy1054"],[30610862,"Fecal Microbiota Transplantation Is Superior to Fidaxomicin for Treatment of Recurrent Clostridium difficile Infection.","Gastroenterology",2019,"Hvas et al.",2,[2],[10.86],15.19,11,9,8,[0,0,0,0,0,0,0,0,0,1,2,0,1,4,0,2],"10.1053/j.gastro.2018.12.019"],[30656645,"Revised FIGO staging for carcinoma of the cervix uteri.","Int J Gynaecol Obstet",2019,"Bhatla et al.",5,[1,9],[15.19,12.55],15.19,9,9,8,[0,0,0,0,0,0,0,0,1,0,2,1,0,2,3,0],"10.1002/ijgo.12749"],[30907957,"Efficacy of Pharmacological Therapies for the Prevention of Fractures in Postmenopausal Women: A Network Meta-Analysis.","J Clin Endocrinol Metab",2019,"Barrionuevo et al.",0,[13,7],[11.58,13.38],15.19,9,9,8,[0,0,0,0,0,0,0,0,0,0,1,2,1,1,4,0],"10.1210/jc.2019-00192"],[30943124,"Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study.","J Clin Oncol",2019,"Chung et al.",3,[1,9],[15.19,13.38],15.19,9,9,7,[0,0,0,0,0,0,0,0,0,1,0,0,1,3,3,1],"10.1200/JCO.18.01265"],[32101663,"Pembrolizumab for Early Triple-Negative Breast Cancer.","N Engl J Med",2020,"Schmid et al.",2,[1],[15.19],15.19,10,9,8,[0,0,0,0,0,0,0,0,0,0,1,3,1,2,2,0],"10.1056/NEJMoa1910549"],[33739462,"Yttrium-90 Radioembolization for the Treatment of Solitary, Unresectable HCC: The LEGACY Study.","Hepatology",2021,"Salem et al.",5,[1,4],[15.19,15.19],15.19,10,9,8,[0,0,0,0,0,0,0,0,0,0,0,2,1,4,2,1],"10.1002/hep.31819"],[34554658,"New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race.","N Engl J Med",2021,"Inker et al.",7,[8],[10.86],15.19,11,9,8,[0,0,0,0,0,0,0,0,0,0,0,1,2,3,2,2],"10.1056/NEJMoa2102953"],[34904799,"Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma.","N Engl J Med",2022,"Tilly et al.",2,[1,10],[13.38,13.38],15.19,9,9,8,[0,0,0,0,0,0,0,0,0,0,0,1,1,3,1,3],"10.1056/NEJMoa2115304"],[35217545,"The effects of plasma exchange in patients with ANCA-associated vasculitis: an updated systematic review and meta-analysis.","BMJ",2022,"Walsh et al.",0,[0,11,14],[12.55,9.94,9.94],15.19,10,9,8,[0,0,0,0,0,0,0,0,0,0,0,1,1,3,4,1],"10.1136/bmj-2021-064604"],[35921640,"Policy Statement: Breastfeeding and the Use of Human Milk.","Pediatrics",2022,"Meek et al.",7,[],[],15.19,11,9,8,[0,0,0,0,0,0,0,0,0,0,0,1,2,4,2,1],"10.1542/peds.2022-057988"],[1828327,"Methotrexate and histologic hepatic abnormalities: a meta-analysis.","Am J Med",1991,"Whiting-O'Keefe et al.",0,[4],[1.35],15.17,9,8,8,[0,3,0,1,0,1,2,1,0,0,1,0,0,0,0,0],""],[2593165,"Projecting individualized 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Spanish Lung Failure Collaborative Group.","N Engl J Med",1995,"Esteban et al.",2,[3],[13.27],15.17,8,8,8,[0,0,0,2,0,1,1,0,0,1,0,1,0,2,0,0],"10.1056/NEJM199502093320601"],[8482629,"Evaluation of the dose for postoperative radiation therapy of head and neck cancer: first report of a prospective randomized trial.","Int J Radiat Oncol Biol Phys",1993,"Peters et al.",2,[1],[15.17],15.17,8,8,8,[1,0,0,2,0,0,1,0,0,2,0,1,0,0,1,0],"10.1016/0360-3016(93)90167-t"],[8624641,"Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial.","Br J Rheumatol",1996,"van den Hoogen et al.",2,[14,11],[13.27,10.83],15.17,8,8,8,[0,0,1,0,0,1,2,1,0,0,0,0,0,2,0,1],"10.1093/rheumatology/35.4.364"],[8968014,"Effect of diuretic-based antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group.","JAMA",1996,"Curb et al.",2,[0,7],[8.47,9.48],15.17,13,8,8,[2,1,2,4,0,0,1,0,0,0,0,0,0,1,0,0],""],[9074366,"Early versus late necrosectomy in severe necrotizing pancreatitis.","Am J Surg",1997,"Mier et al.",2,[4],[13.27],15.17,9,8,8,[0,1,2,0,2,0,1,1,0,0,0,0,0,1,0,0],"10.1016/S0002-9610(96)00425-4"],[9192929,"Training with supplemental oxygen in patients with COPD and hypoxaemia at peak exercise.","Eur Respir J",1997,"Rooyackers et al.",2,[3],[15.17],15.17,8,8,8,[1,1,1,1,0,0,0,0,0,0,1,0,0,3,0,0],"10.1183/09031936.97.10061278"],[9278206,"Is metronidazole teratogenic? 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Community Program for Clinical Research on AIDS and the AIDS Clinical Trials Group.","N Engl J Med",1998,"El-Sadr et al.",2,[2,12,3],[13.27,4.04,2.69],15.17,9,8,8,[0,1,2,0,0,1,0,0,0,0,1,0,0,2,2,0],"10.1056/NEJM199812243392604"],[10859037,"Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial.","Lancet",2000,"Plant et al.",2,[3],[15.17],15.17,8,8,8,[1,1,0,0,0,1,3,0,0,0,1,0,0,1,0,0],"10.1016/s0140-6736(00)02323-0"],[11118174,"Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials.","BMJ",2000,"Rodgers et al.",1,[0],[10.16],15.17,11,8,8,[0,0,1,3,1,1,1,0,0,0,0,1,0,0,0,0],"10.1136/bmj.321.7275.1493"],[11172192,"Liver biopsy.","N Engl J Med",2001,"Bravo et al.",6,[4],[12.63],15.17,9,8,8,[1,0,0,0,3,0,0,0,0,1,0,1,0,1,1,0],"10.1056/NEJM200102153440706"],[11294800,"Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia.","Circulation",2001,"Lewis et al.",3,[10],[6.2],15.17,8,8,8,[2,2,1,0,0,0,0,1,0,1,0,1,0,0,0,0],"10.1161/01.cir.103.14.1838"],[11343232,"A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varices.","Hepatology",2001,"Lo et al.",2,[4],[15.17],15.17,8,8,8,[0,2,2,1,0,0,0,0,1,0,1,0,0,0,1,0],"10.1053/jhep.2001.24116"],[11465701,"Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study.","Arthritis Rheum",2001,"van Ede et al.",2,[11],[1.0],15.17,8,8,7,[0,3,0,1,1,1,0,0,0,1,0,0,0,0,0,1],"10.1002/1529-0131(200107)44:7<1515::AID-ART273>3.0.CO;2-7"],[11466691,"Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group.","Cancer",2001,"Stoeckle et al.",5,[1],[15.17],15.17,8,8,8,[1,0,1,0,2,2,0,0,0,0,0,1,1,0,0,0],"10.1002/1097-0142(20010715)92:2<359::aid-cncr1331>3.0.co;2-y"],[11914998,"Definitions of cytomegalovirus infection and disease in transplant recipients.","Clin Infect Dis",2002,"Ljungman et al.",6,[2],[8.47],15.17,8,8,8,[1,0,3,0,1,1,0,0,0,0,0,0,0,1,0,1],"10.1086/339329"],[12050337,"Results of screening colonoscopy among persons 40 to 49 years of age.","N Engl J Med",2002,"Imperiale et al.",5,[1,4],[15.17,15.17],15.17,11,8,9,[0,2,1,0,0,0,1,2,0,0,0,1,1,0,0,0],"10.1056/NEJM200206063462304"],[12202709,"Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET): a meta-analysis.","Radiology",2002,"Kinkel et al.",0,[1,4],[15.17,12.63],15.17,8,8,8,[2,1,0,1,1,0,2,0,0,0,0,0,1,0,0,0],"10.1148/radiol.2243011362"],[12243637,"Anemia and blood transfusion in critically ill patients.","JAMA",2002,"Vincent et al.",7,[10],[12.63],15.17,9,8,8,[1,1,2,0,0,1,0,0,0,2,0,0,0,0,1,0],"10.1001/jama.288.12.1499"],[12401421,"Self-management approaches for people with chronic conditions: a review.","Patient Educ Couns",2002,"Barlow et al.",6,[],[],15.17,8,8,8,[0,0,0,2,0,1,2,0,1,0,1,0,0,1,0,0],"10.1016/s0738-3991(02)00032-0"],[12646670,"Preventing complications of central venous catheterization.","N Engl J Med",2003,"McGee et al.",6,[0,2],[10.16,8.47],15.17,9,8,8,[0,2,1,2,0,0,1,0,1,0,0,0,0,0,2,0],"10.1056/NEJMra011883"],[12654134,"Histological features associated with relapse after corticosteroid withdrawal in type 1 autoimmune hepatitis.","Liver Int",2003,"Czaja et al.",5,[4,6],[15.17,0.0],15.17,8,8,8,[1,0,0,0,0,0,1,0,0,1,0,1,1,0,3,0],"10.1034/j.1600-0676.2003.00810.x"],[12788569,"Effect of enalapril on 12-year survival and life expectancy in patients with left ventricular systolic dysfunction: a follow-up study.","Lancet",2003,"Jong et al.",2,[0],[12.63],15.17,13,10,7,[0,1,1,0,2,2,0,0,3,0,0,1,0,0,0,0],"10.1016/S0140-6736(03)13501-5"],[12829555,"Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials.","BMJ",2003,"Law et al.",0,[0],[15.17],15.17,15,8,9,[0,0,0,0,0,0,1,1,1,0,0,0,0,2,3,2],"10.1136/bmj.326.7404.1427"],[12860945,"Prospective, randomized, multicenter trial on the antiproliferative effect of lanreotide, interferon alfa, and their combination for therapy of metastatic neuroendocrine gastroenteropancreatic tumors--the International Lanreotide and Interferon Alfa Study Group.","J Clin Oncol",2003,"Faiss et al.",2,[1,4,7],[12.63,9.02,4.65],15.17,8,8,8,[0,2,1,1,2,0,1,0,0,0,0,0,0,0,1,0],"10.1200/JCO.2003.12.142"],[14643276,"Gadolinium enhanced cardiovascular magnetic resonance in Anderson-Fabry disease. Evidence for a disease specific abnormality of the myocardial interstitium.","Eur Heart J",2003,"Moon et al.",3,[0,17,5],[15.17,2.69,1.0],15.17,12,8,8,[2,0,1,2,0,0,1,0,0,1,1,0,0,0,0,0],"10.1016/j.ehj.2003.09.017"],[15057881,"A breast cancer prediction model incorporating familial and personal risk factors.","Stat Med",2004,"Tyrer et al.",7,[1],[15.17],15.17,8,8,8,[0,0,1,0,2,0,1,0,1,0,0,0,1,2,0,0],"10.1002/sim.1668"],[15188371,"Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: a multinational, double-blind, randomized, placebo-controlled clinical trial.","Arthritis Rheum",2004,"Kaltwasser et al.",2,[11,13,14],[13.27,13.27,13.27],15.17,9,8,8,[1,3,1,0,0,0,1,0,1,0,1,0,0,0,0,0],"10.1002/art.20253"],[15286545,"A prospective, randomized, study comparing early percutaneous dilational tracheotomy to prolonged translaryngeal intubation (delayed tracheotomy) in critically ill medical patients.","Crit Care Med",2004,"Rumbak et al.",2,[3,2],[12.63,2.69],15.17,9,8,9,[1,0,0,0,0,1,2,0,0,2,0,1,0,1,0,0],"10.1097/01.ccm.0000134835.05161.b6"],[15516683,"Pulmonary-Hepatic vascular Disorders (PHD).","Eur Respir J",2004,"Rodríguez-Roisin et al.",6,[3,4,0],[4.65,10.83,2.69],15.17,8,8,8,[0,0,1,2,1,1,0,1,0,0,0,0,0,2,0,0],"10.1183/09031936.04.00010904"],[15522474,"Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report.","Eur Heart J",2004,"Pennell et al.",4,[0],[15.17],15.17,9,8,8,[0,2,2,1,0,0,0,1,0,1,0,1,0,0,0,0],"10.1016/j.ehj.2004.06.040"],[15529377,"Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial.","Arthritis Rheum",2004,"St Clair et al.",2,[11],[13.27],15.17,8,8,8,[2,2,1,1,1,0,1,0,0,0,0,0,0,0,0,0],"10.1002/art.20568"],[15547162,"Prognostic significance of left ventricular mass change during treatment of hypertension.","JAMA",2004,"Devereux et al.",2,[0],[15.17],15.17,10,8,8,[0,0,2,0,0,1,1,2,0,0,0,0,0,1,0,1],"10.1001/jama.292.19.2350"],[15664225,"Analysis of air contrast barium enema, computed tomographic colonography, and colonoscopy: prospective comparison.","Lancet",2005,"Rockey et al.",7,[1,4],[15.17,15.17],15.17,11,8,9,[0,2,2,1,1,2,0,0,0,0,0,0,0,0,1,0],"10.1016/S0140-6736(05)17784-8"],[15813835,"Effect of the administration schedule on the therapeutic efficacy of oral pancreatic enzyme supplements in patients with exocrine pancreatic insufficiency: a randomized, three-way crossover study.","Aliment Pharmacol Ther",2005,"Domínguez-Muñoz et al.",2,[4],[15.17],15.17,9,8,8,[0,1,3,0,1,0,0,0,0,2,0,0,0,1,1,0],"10.1111/j.1365-2036.2005.02390.x"],[15855978,"A prospective trial comparing wireless capsule endoscopy and barium contrast series for small-bowel surveillance in hereditary GI polyposis syndromes.","Gastrointest Endosc",2005,"Mata et al.",3,[4,1,17],[15.17,8.47,4.65],15.17,8,8,8,[1,0,0,0,2,0,2,0,0,1,0,0,0,1,0,1],"10.1016/s0016-5107(05)00289-0"],[15867775,"Modern surgical treatment of massive pulmonary embolism: results in 47 consecutive patients after rapid diagnosis and aggressive surgical approach.","J Thorac Cardiovasc Surg",2005,"Leacche et al.",5,[0,3],[15.17,6.2],15.17,8,8,8,[3,1,1,1,0,0,0,0,0,1,0,0,0,1,0,0],"10.1016/j.jtcvs.2004.10.023"],[16129366,"Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial.","Lancet Oncol",2005,"Burmeister et al.",2,[1,4],[15.17,15.17],15.17,8,8,8,[2,0,0,0,2,0,0,0,1,1,0,0,1,1,0,0],"10.1016/S1470-2045(05)70288-6"],[16344051,"Prevalence of Barrett's esophagus in the general population: an endoscopic study.","Gastroenterology",2005,"Ronkainen et al.",7,[4,1],[15.17,10.83],15.17,8,8,8,[0,1,0,1,0,3,0,1,1,0,0,0,1,0,0,0],"10.1053/j.gastro.2005.08.053"],[16687434,"Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations.","Gut",2006,"Lanas et al.",5,[4],[10.83],15.17,9,8,9,[0,1,0,1,0,0,0,0,1,3,0,1,0,1,0,0],"10.1136/gut.2005.080754"],[16914034,"How long do nosocomial pathogens persist on inanimate surfaces? A systematic review.","BMC Infect Dis",2006,"Kramer et al.",1,[2],[10.83],15.17,8,8,8,[0,0,0,2,0,1,0,1,0,1,0,0,0,1,2,0],"10.1186/1471-2334-6-130"],[16988856,"Percutaneous CT scan-guided drainage vs. antibiotherapy alone for Hinchey II diverticulitis: a case-control study.","Dis Colon Rectum",2006,"Brandt et al.",5,[4,2],[12.63,1.0],15.17,9,8,8,[0,0,1,2,2,1,1,0,0,1,0,0,0,0,0,0],"10.1007/s10350-006-0613-3"],[17235046,"Induction chemoradiation and surgical resection for superior sulcus non-small-cell lung carcinomas: long-term results of Southwest Oncology Group Trial 9416 (Intergroup Trial 0160).","J Clin Oncol",2007,"Rusch et al.",3,[1,3],[15.17,15.17],15.17,8,8,8,[0,0,2,0,1,2,0,0,0,0,0,1,1,0,1,0],"10.1200/JCO.2006.08.2826"],[17261680,"Migraine prevalence, disease burden, and the need for preventive therapy.","Neurology",2007,"Lipton et al.",7,[5],[10.16],15.17,9,8,8,[0,2,2,0,0,0,0,0,1,1,0,1,0,1,0,0],"10.1212/01.wnl.0000252808.97649.21"],[17371885,"Comparison of treatment strategies in early rheumatoid arthritis: a randomized trial.","Ann Intern Med",2007,"Goekoop-Ruiterman et al.",2,[11],[13.27],15.17,8,8,8,[1,2,0,0,0,0,0,2,1,1,0,0,0,1,0,0],"10.7326/0003-4819-146-6-200703200-00005"],[17401086,"68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT.","J Nucl Med",2007,"Gabriel et al.",3,[1,4],[15.17,8.47],15.17,8,8,8,[0,2,1,0,1,1,2,0,0,0,0,0,1,0,0,0],"10.2967/jnumed.106.035667"],[17403073,"The efficacy and safety of bile Acid binding agents, opioid antagonists, or rifampin in the treatment of cholestasis-associated pruritus.","Am J Gastroenterol",2007,"Tandon et al.",6,[4,14],[10.83,2.69],15.17,8,8,8,[0,0,0,0,1,0,1,3,1,0,0,0,0,1,0,1],"10.1111/j.1572-0241.2007.01200.x"],[17470830,"Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis: a randomized trial.","Ann Intern Med",2007,"Hoffman et al.",2,[0,11,5],[13.27,10.83,4.65],15.17,9,8,8,[2,2,0,0,0,1,1,0,0,1,1,0,0,0,0,0],"10.7326/0003-4819-146-9-200705010-00004"],[17560447,"Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study.","Lancet",2007,"Eapen et al.",3,[1,10],[12.63,12.63],15.17,11,10,7,[1,2,0,0,2,0,0,0,0,3,1,0,0,0,2,0],"10.1016/S0140-6736(07)60915-5"],[17569110,"Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond.","Stat Med",2008,"Pencina et al.",7,[0],[4.65],15.17,10,8,9,[1,0,0,1,1,0,3,0,0,0,0,0,1,0,1,0],"10.1002/sim.2929"],[17940231,"Invasive methicillin-resistant Staphylococcus aureus infections in the United States.","JAMA",2007,"Klevens et al.",7,[2],[15.17],15.17,8,8,8,[3,0,0,1,1,0,1,1,1,0,0,0,0,0,0,0],"10.1001/jama.298.15.1763"],[18061597,"EUS-guided FNA of regional lymph nodes in patients with unresectable hilar cholangiocarcinoma.","Gastrointest Endosc",2008,"Gleeson et al.",5,[1,4],[13.27,15.17],15.17,8,8,8,[0,0,2,0,0,1,1,0,0,1,0,0,1,2,0,0],"10.1016/j.gie.2007.07.018"],[18182991,"Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: a systematic review and meta-analysis.","Br J Cancer",2008,"Uronis et al.",0,[3,1],[10.83,1.0],15.17,9,8,9,[0,1,1,1,2,0,0,0,0,0,0,2,0,0,0,1],"10.1038/sj.bjc.6604161"],[18203817,"Randomised trial of CPAP vs bilevel support in the treatment of obesity hypoventilation syndrome without severe nocturnal desaturation.","Thorax",2008,"Piper et al.",2,[3,5,7],[15.17,8.47,2.69],15.17,8,8,8,[2,0,2,0,0,0,1,0,1,1,0,0,0,0,1,0],"10.1136/thx.2007.081315"],[18223031,"Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT).","Diabetes Care",2008,"Kahn et al.",2,[7,13],[13.27,4.65],15.17,9,8,8,[0,2,2,0,0,0,1,0,0,1,2,1,0,0,0,0],"10.2337/dc07-2270"],[18294997,"Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls.","Lancet",2008,"Beral et al.",0,[1,9,7],[11.58,11.58,8.47],15.17,10,10,7,[0,1,0,0,0,0,1,4,2,1,0,0,0,1,0,0],"10.1016/S0140-6736(08)60167-1"],[18393319,"Recombinant factor VIIa for variceal bleeding in patients with advanced cirrhosis: A randomized, controlled trial.","Hepatology",2008,"Bosch et al.",2,[4],[13.27],15.17,8,8,8,[0,2,2,0,0,0,1,0,0,1,1,1,0,0,0,0],"10.1002/hep.22216"],[18403624,"Benign and malignant thyroid nodules: US differentiation--multicenter retrospective study.","Radiology",2008,"Moon et al.",5,[7,1],[15.17,8.47],15.17,8,8,8,[0,1,1,1,0,2,0,1,0,2,0,0,0,0,0,0],"10.1148/radiol.2473070944"],[18515795,"Pancreatic neuroendocrine tumors (PNETs): incidence, prognosis and recent trend toward improved survival.","Ann Oncol",2008,"Halfdanarson et al.",7,[1,4,7],[15.17,11.38,11.38],15.17,9,8,8,[0,2,1,1,3,1,1,0,0,0,0,0,0,0,0,0],"10.1093/annonc/mdn351"],[18617440,"Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study.","Lancet Oncol",2008,"Brantsch et al.",5,[1,14],[15.17,15.17],15.17,11,8,8,[0,0,0,0,2,0,0,3,0,3,0,0,1,1,0,1],"10.1016/S1470-2045(08)70178-5"],[18618495,"Radioembolization with selective internal radiation microspheres for neuroendocrine liver metastases.","Cancer",2008,"King et al.",3,[1,4],[15.17,9.48],15.17,9,8,8,[0,2,2,0,2,0,1,0,0,0,1,0,0,0,0,1],"10.1002/cncr.23685"],[18761704,"Azathioprine treatment during lactation.","Aliment Pharmacol Ther",2008,"Christensen et al.",7,[4],[4.65],15.17,8,8,8,[1,0,0,0,2,1,0,0,1,0,1,0,2,0,0,0],"10.1111/j.1365-2036.2008.03843.x"],[18801868,"Perinatal mortality and other severe adverse pregnancy outcomes associated with treatment of cervical intraepithelial neoplasia: meta-analysis.","BMJ",2008,"Arbyn et al.",0,[9,1],[15.17,12.63],15.17,9,8,9,[1,3,1,1,1,0,0,0,0,0,0,0,0,0,0,1],"10.1136/bmj.a1284"],[18843708,"Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers.","Cochrane Database Syst Rev",2008,"van Rijen et al.",0,[2],[10.16],15.17,10,8,8,[3,1,1,1,0,0,2,0,1,0,0,0,0,0,0,0],"10.1002/14651858.CD006216.pub2"],[18927461,"Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST).","Stroke",2008,"Wahlgren et al.",3,[0,5],[15.17,15.17],15.17,11,8,8,[0,1,4,0,0,0,0,1,1,1,0,0,0,0,0,2],"10.1161/STROKEAHA.107.510768"],[19008265,"Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis.","BMJ",2008,"Ford et al.",0,[4],[15.17],15.17,8,8,8,[2,0,0,0,1,0,2,0,0,1,0,0,1,0,1,0],"10.1136/bmj.a2313"],[19033370,"Clinical review 1: Bisphosphonate use in childhood osteoporosis.","J Clin Endocrinol Metab",2009,"Bachrach et al.",6,[13,7],[6.2,2.69],15.17,8,8,8,[2,1,1,2,1,0,0,1,0,0,0,0,0,0,0,0],"10.1210/jc.2008-1531"],[19246088,"Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial.","Lancet",2009,"Wardlaw et al.",2,[13],[15.17],15.17,10,8,8,[2,0,1,3,0,0,0,1,0,0,0,0,1,0,2,0],"10.1016/S0140-6736(09)60010-6"],[19276237,"An ultrasonogram reporting system for thyroid nodules stratifying cancer risk for clinical management.","J Clin Endocrinol Metab",2009,"Horvath et al.",5,[7,1],[15.17,10.83],15.17,8,8,8,[1,0,0,0,0,2,1,1,0,2,0,0,0,0,0,1],"10.1210/jc.2008-1724"],[19282306,"Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study).","Gut",2009,"Seifert et al.",5,[4],[15.17],15.17,8,8,8,[0,1,0,0,0,2,1,0,0,0,1,1,0,2,0,0],"10.1136/gut.2008.163733"],[19411100,"Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial.","Lancet",2009,"Turpie et al.",2,[0],[15.17],15.17,9,8,8,[0,2,1,0,1,0,1,3,0,0,0,0,0,0,0,1],"10.1016/S0140-6736(09)60734-0"],[19841031,"An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients.","J Antimicrob Chemother",2009,"Viscoli et al.",3,[2,1,10],[15.17,4.65,4.04],15.17,8,8,8,[3,0,0,1,0,1,1,0,1,0,0,0,0,0,1,0],"10.1093/jac/dkp355"],[19841323,"Cancer during pregnancy: an analysis of 215 patients emphasizing the obstetrical and the neonatal outcomes.","J Clin Oncol",2010,"Van Calsteren et al.",7,[1,9],[15.17,12.63],15.17,9,8,8,[0,0,3,0,1,1,0,0,0,0,0,1,0,0,1,2],"10.1200/JCO.2009.23.2801"],[20062093,"Caspofungin first-line therapy for invasive aspergillosis in allogeneic hematopoietic stem cell transplant patients: an European Organisation for Research and Treatment of Cancer study.","Bone Marrow Transplant",2010,"Herbrecht et al.",3,[2],[15.17],15.17,8,8,8,[3,0,0,1,0,1,1,0,1,0,0,0,0,0,1,0],"10.1038/bmt.2009.334"],[20159883,"Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis.","Hum Reprod Update",2010,"Moran et al.",0,[7,1,9],[8.47,6.77,6.77],15.17,10,8,8,[1,0,1,1,2,2,0,0,0,0,0,1,0,0,0,0],"10.1093/humupd/dmq001"],[20196795,"Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009.","Epilepsia",2010,"Berg et al.",7,[5],[12.63],15.17,9,8,9,[0,1,1,1,0,1,0,0,0,0,0,2,0,0,2,0],"10.1111/j.1528-1167.2010.02522.x"],[20339026,"Biomarker-based risk stratification for previously untreated medullary thyroid cancer.","J Clin Endocrinol Metab",2010,"Machens et al.",5,[1,7],[13.27,15.17],15.17,8,8,8,[0,0,0,2,1,0,0,0,1,2,0,0,0,1,1,0],"10.1210/jc.2009-2368"],[20400681,"Rebalanced hemostasis in patients with liver disease: evidence and clinical consequences.","Blood",2010,"Lisman et al.",7,[4,10],[12.63,6.77],15.17,9,8,8,[0,0,0,0,0,0,0,0,1,2,2,0,0,1,1,1],"10.1182/blood-2010-02-261891"],[20472172,"Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials.","Lancet",2010,"Lees et al.",7,[0,5],[15.17,15.17],15.17,9,8,8,[1,1,4,0,1,0,1,0,0,0,0,0,0,0,0,1],"10.1016/S0140-6736(10)60491-6"],[20492521,"Refractory ascites: pathogenesis, definition and therapy of a severe complication in patients with cirrhosis.","Liver Int",2010,"Salerno et al.",6,[4],[15.17],15.17,8,8,8,[0,0,0,0,0,0,0,0,1,2,2,1,0,1,0,1],"10.1111/j.1478-3231.2010.02272.x"],[20701962,"Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial.","Lancet",2010,"Klazen et al.",2,[13,7],[15.17,3.39],15.17,10,8,8,[1,0,0,3,0,0,1,2,0,0,0,0,1,0,2,0],"10.1016/S0140-6736(10)60954-3"],[20878942,"Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery.","Br J Surg",2010,"Noorani et al.",0,[2],[8.47],15.17,9,8,8,[0,1,0,0,1,0,2,0,1,2,1,0,0,0,0,0],"10.1002/bjs.7214"],[21357346,"Postnatal glucose homeostasis in late-preterm and term infants.","Pediatrics",2011,"Adamkin et al.",6,[7,17],[6.77,1.0],15.17,9,8,9,[0,0,2,2,1,2,1,0,0,0,0,0,0,0,0,1],"10.1542/peds.2010-3851"],[21367728,"β-D-glucan assay for the diagnosis of invasive fungal infections: a meta-analysis.","Clin Infect Dis",2011,"Karageorgopoulos et al.",0,[2],[10.16],15.17,8,8,8,[0,1,0,1,1,3,0,0,1,0,0,0,0,1,0,0],"10.1093/cid/ciq206"],[21388969,"Improving the transition between paediatric and adult healthcare: a systematic review.","Arch Dis Child",2011,"Crowley et al.",1,[7],[6.77],15.17,8,8,8,[1,1,0,1,0,1,3,0,0,0,0,0,0,0,0,1],"10.1136/adc.2010.202473"],[21412886,"Transarterial (chemo)embolisation for unresectable hepatocellular carcinoma.","Cochrane Database Syst Rev",2011,"Oliveri et al.",0,[1,4],[15.17,15.17],15.17,9,8,8,[0,3,0,0,1,1,0,1,0,1,1,0,0,0,0,0],"10.1002/14651858.CD004787.pub2"],[21556038,"High-dose ursodeoxycholic acid is associated with the development of colorectal neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis.","Am J Gastroenterol",2011,"Eaton et al.",2,[4,1],[15.17,2.69],15.17,8,8,8,[0,1,0,0,2,0,1,2,1,0,0,1,0,0,0,0],"10.1038/ajg.2011.156"],[21674554,"The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury.","Hepatology",2011,"Suzuki et al.",7,[4],[15.17],15.17,9,8,8,[0,0,0,0,2,0,1,0,0,2,1,0,1,0,2,0],"10.1002/hep.24481"],[21709194,"Comprehensive geriatric assessment in the decision-making process in elderly patients with cancer: ELCAPA study.","J Clin Oncol",2011,"Caillet et al.",5,[1],[15.17],15.17,8,8,8,[0,1,0,1,0,0,2,2,0,1,0,0,0,0,1,0],"10.1200/JCO.2010.31.0664"],[21774708,"ABVD versus BEACOPP for Hodgkin's lymphoma when high-dose salvage is planned.","N Engl J Med",2011,"Viviani et al.",2,[1,10],[15.17,15.17],15.17,10,8,8,[0,0,0,3,2,0,1,1,0,0,0,0,0,2,0,1],"10.1056/NEJMoa1100340"],[21865943,"Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease.","Ann Surg",2011,"Neal et al.",5,[2,4],[10.83,4.65],15.17,8,8,8,[0,0,0,1,1,0,0,1,0,1,3,0,0,1,0,0],"10.1097/SLA.0b013e31822ade48"],[21944912,"Compression therapy in mixed ulcers increases venous output and arterial perfusion.","J Vasc Surg",2012,"Mosti et al.",7,[14,0],[6.77,12.63],15.17,9,8,8,[0,0,0,1,2,1,0,0,1,0,2,0,0,0,1,0],"10.1016/j.jvs.2011.07.071"],[22047557,"A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.","N Engl J Med",2011,"Ramsey et al.",2,[3,17,4],[12.63,13.27,10.83],15.17,8,8,8,[0,0,0,3,0,1,0,1,0,0,1,0,1,1,0,0],"10.1056/NEJMoa1105185"],[22193671,"The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults.","Am J Psychiatry",2011,"Posner et al.",7,[6,5],[4.65,2.69],15.17,9,8,8,[0,0,1,0,0,0,0,1,0,1,2,0,0,2,2,0],"10.1176/appi.ajp.2011.10111704"],[22261362,"Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial.","Lancet Oncol",2012,"Bourhis et al.",2,[1],[15.17],15.17,9,8,8,[0,0,0,2,0,0,1,0,0,1,1,1,0,0,3,0],"10.1016/S1470-2045(11)70346-1"],[22570462,"Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate.","JAMA",2012,"Matsushita et al.",0,[0,8],[8.47,4.04],15.17,12,8,8,[0,0,1,1,0,2,2,1,0,0,0,0,0,1,0,0],"10.1001/jama.2012.3954"],[22614989,"Management of immune-related adverse events and kinetics of response with ipilimumab.","J Clin Oncol",2012,"Weber et al.",6,[1,14],[13.27,6.77],15.17,8,8,8,[0,0,1,0,1,0,1,2,2,0,1,0,0,0,0,0],"10.1200/JCO.2012.41.6750"],[22618923,"Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial.","JAMA",2012,"Barbé et al.",2,[0,3,5],[4.65,8.47,8.47],15.17,10,8,8,[0,0,2,0,0,0,2,1,1,1,0,1,0,0,0,0],"10.1001/jama.2012.4366"],[22661725,"Bridging the gap: an integrated paediatric to adult clinical service for young adults with kidney failure.","BMJ",2012,"Harden et al.",7,[8],[2.69],15.17,8,8,8,[0,0,0,1,1,0,1,0,0,0,1,0,0,3,0,1],"10.1136/bmj.e3718"],[22895916,"Hormone therapy in postmenopausal women and risk of endometrial hyperplasia.","Cochrane Database Syst Rev",2012,"Furness et al.",0,[9,1],[8.47,8.47],15.17,10,8,8,[0,0,0,0,0,1,2,1,0,0,1,0,0,2,2,0],"10.1002/14651858.CD000402.pub4"],[22949223,"Abatacept and reduced immune response to pandemic 2009 influenza A/H1N1 vaccination in patients with rheumatoid arthritis.","Arthritis Care Res (Hoboken)",2013,"Ribeiro et al.",2,[11],[15.17],15.17,10,8,7,[0,0,0,1,0,2,1,0,2,0,1,0,0,0,0,1],"10.1002/acr.21838"],[22961916,"Radioiodine therapy in benign thyroid diseases: effects, side effects, and factors affecting therapeutic outcome.","Endocr Rev",2012,"Bonnema et al.",6,[7],[15.17],15.17,8,8,8,[0,0,0,1,0,2,0,1,0,1,0,0,2,0,1,0],"10.1210/er.2012-1030"],[22975218,"Superiority of denosumab to zoledronic acid for prevention of skeletal-related events: a combined analysis of 3 pivotal, randomised, phase 3 trials.","Eur J Cancer",2012,"Lipton et al.",0,[1,13],[10.83,6.2],15.17,8,8,8,[0,0,0,2,0,1,2,0,1,0,0,0,1,0,0,1],"10.1016/j.ejca.2012.08.002"],[23312829,"Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial.","Lancet",2013,"Bissler et al.",2,[1],[15.17],15.17,8,8,8,[0,0,0,0,0,1,0,0,1,1,0,0,2,1,2,0],"10.1016/S0140-6736(12)61767-X"],[23423795,"Magnetic resonance elastography of liver: technique, analysis, and clinical applications.","J Magn Reson Imaging",2013,"Venkatesh et al.",6,[4,1],[10.16,1.0],15.17,8,8,8,[0,0,0,0,0,1,2,0,0,2,0,0,1,0,1,1],"10.1002/jmri.23731"],[23440780,"Vaccines for preventing pneumococcal infection in adults.","Cochrane Database Syst Rev",2013,"Moberley et al.",0,[2,3],[8.47,6.77],15.17,8,8,8,[0,0,0,1,0,2,0,0,1,0,2,1,0,0,1,0],"10.1002/14651858.CD000422.pub3"],[23470618,"New oral anticoagulants increase risk for gastrointestinal bleeding: a systematic review and meta-analysis.","Gastroenterology",2013,"Holster et al.",7,[4],[10.83],15.17,10,8,8,[0,0,0,1,1,3,0,0,0,0,2,0,0,1,0,1],"10.1053/j.gastro.2013.02.041"],[23497608,"Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials.","Crit Care",2013,"Alhazzani et al.",0,[3],[9.3],15.17,11,8,7,[0,0,0,0,1,2,1,0,1,3,0,0,0,0,1,0],"10.1186/cc12557"],[23754213,"The use of computed tomography in pediatrics and the associated radiation exposure and estimated cancer risk.","JAMA Pediatr",2013,"Miglioretti et al.",5,[13,1],[6.2,2.69],15.17,11,8,9,[0,0,0,1,0,0,0,2,0,1,0,1,0,2,1,0],"10.1001/jamapediatrics.2013.311"],[23891974,"Reliability and initial validation of the ulcerative colitis endoscopic index of severity.","Gastroenterology",2013,"Travis et al.",5,[4],[15.17],15.17,9,8,8,[0,0,1,0,1,0,0,1,2,0,0,0,0,1,3,0],"10.1053/j.gastro.2013.07.024"],[23917950,"Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013.","Ann Oncol",2013,"Goldhirsch et al.",4,[1],[15.17],15.17,9,8,8,[0,0,1,0,0,4,1,0,1,0,0,1,0,0,1,0],"10.1093/annonc/mdt303"],[24104372,"Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial.","JAMA",2013,"Oettle et al.",2,[1,4,7],[15.17,15.17,15.17],15.17,9,8,8,[0,0,0,1,2,0,1,0,1,0,0,0,2,1,0,0],"10.1001/jama.2013.279201"],[24369411,"No evidence for an increased risk of adverse pregnancy outcome after paternal low-dose methotrexate: an observational cohort study.","Rheumatology (Oxford)",2014,"Weber-Schoendorfer et al.",5,[17,9],[1.0,0.0],15.17,9,8,8,[0,0,0,0,0,1,2,0,1,1,0,0,1,0,2,0],"10.1093/rheumatology/ket390"],[24385423,"Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia.","Cochrane Database Syst Rev",2014,"Lunn et al.",0,[5,13,7],[5.08,3.1,0.0],15.17,9,8,8,[0,0,0,0,0,2,2,1,1,1,0,2,0,0,0,0],"10.1002/14651858.CD007115.pub3"],[25154831,"Comorbidity-age index: a clinical measure of biologic age before allogeneic hematopoietic cell transplantation.","J Clin Oncol",2014,"Sorror et al.",5,[1,10],[12.76,12.76],15.17,11,10,7,[0,0,0,0,0,0,3,1,1,2,2,0,0,1,0,0],"10.1200/JCO.2013.53.8157"],[25199059,"Mepolizumab treatment in patients with severe eosinophilic asthma.","N Engl J Med",2014,"Ortega et al.",2,[3,12,10],[10.16,10.16,0.0],15.17,9,8,8,[0,0,0,0,1,0,0,0,0,2,1,2,1,0,0,1],"10.1056/NEJMoa1403290"],[25243839,"Lactulose vs polyethylene glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial.","JAMA Intern Med",2014,"Rahimi et al.",2,[4,5,7],[15.17,6.77,6.77],15.17,8,8,8,[0,0,0,0,0,0,0,0,1,1,0,1,3,1,0,1],"10.1001/jamainternmed.2014.4746"],[25545380,"The effect of 6 versus 9 years of zoledronic acid treatment in osteoporosis: a randomized second extension to the HORIZON-Pivotal Fracture Trial (PFT).","J Bone Miner Res",2015,"Black et al.",2,[13,7],[15.17,15.17],15.17,9,8,8,[0,0,0,0,0,2,0,0,2,2,0,0,1,1,0,1],"10.1002/jbmr.2442"],[25621434,"Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study.","JAMA Intern Med",2015,"Gray et al.",5,[6,5],[1.0,0.0],15.17,9,8,8,[0,0,0,0,0,0,1,2,1,1,0,0,0,1,2,0],"10.1001/jamainternmed.2014.7663"],[25639627,"Analysis of cell-free DNA in maternal blood in screening for fetal aneuploidies: updated meta-analysis.","Ultrasound Obstet Gynecol",2015,"Gil et al.",0,[17,5],[10.83,2.69],15.17,9,8,9,[0,0,0,0,2,2,2,1,0,0,1,0,0,0,1,0],"10.1002/uog.14791"],[25864112,"Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy.","Eur J Obstet Gynecol Reprod Biol",2015,"Geenes et al.",7,[4,9],[15.17,6.2],15.17,9,8,8,[0,0,0,0,0,0,0,1,0,0,1,2,2,1,0,1],"10.1016/j.ejogrb.2015.03.020"],[26196445,"Hepatocellular Carcinoma in the Absence of Cirrhosis in United States Veterans is Associated With Nonalcoholic Fatty Liver Disease.","Clin Gastroenterol Hepatol",2016,"Mittal et al.",5,[4,1],[15.17,4.65],15.17,10,8,8,[0,0,0,0,0,0,0,1,0,0,1,2,1,2,0,2],"10.1016/j.cgh.2015.07.019"],[26377054,"Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes Study.","Lancet Diabetes Endocrinol",2015,"Diabetes Prevention Program Research Gro",2,[7,0],[15.17,1.0],15.17,8,8,8,[0,0,0,0,0,0,0,0,1,1,0,2,1,2,0,1],"10.1016/S2213-8587(15)00291-0"],[26427566,"PI-RADS Prostate Imaging - Reporting and Data System: 2015, Version 2.","Eur Urol",2016,"Weinreb et al.",7,[1,8,9],[15.17,13.27,13.27],15.17,9,8,8,[0,0,0,0,0,1,2,0,1,2,2,0,1,0,0,0],"10.1016/j.eururo.2015.08.052"],[26503201,"Ablative Radiotherapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma: A Retrospective Dose Response Analysis.","J Clin Oncol",2016,"Tao et al.",5,[1,4],[15.17,15.17],15.17,9,8,8,[0,0,0,0,0,0,0,0,0,1,1,1,2,3,1,0],"10.1200/JCO.2015.61.3778"],[26659452,"Liver stiffness in nonalcoholic fatty liver disease: A comparison of supersonic shear imaging, FibroScan, and ARFI with liver biopsy.","Hepatology",2016,"Cassinotto et al.",3,[4],[15.17],15.17,10,8,10,[0,0,0,0,0,0,2,1,1,0,1,2,0,1,0,0],"10.1002/hep.28394"],[26946343,"Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease After Ileocolonic Resection.","Gastroenterology",2016,"Regueiro et al.",2,[4],[15.17],15.17,9,8,8,[0,0,0,0,0,0,2,1,1,0,0,0,1,1,3,0],"10.1053/j.gastro.2016.02.072"],[27317986,"Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline.","J Urol",2016,"Chang et al.",1,[1,8],[15.17,15.17],15.17,9,8,8,[0,0,0,0,0,0,0,0,0,1,2,0,2,2,1,1],"10.1016/j.juro.2016.06.049"],[27532829,"A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.","N Engl J Med",2016,"Nevens et al.",2,[4],[15.17],15.17,9,8,8,[0,0,0,0,0,0,1,2,1,1,0,1,0,2,0,0],"10.1056/NEJMoa1509840"],[27815525,"ASPEN Safe Practices for Enteral Nutrition Therapy [Formula: see text].","JPEN J Parenter Enteral Nutr",2017,"Boullata et al.",7,[1,2],[5.08,5.08],15.17,9,8,8,[0,0,0,0,0,0,0,2,0,1,3,1,0,0,1,1],"10.1177/0148607116673053"],[28346297,"Exposure to Mycophenolate and Fatherhood.","Transplantation",2017,"Midtvedt et al.",5,[9,8],[1.0,1.0],15.17,9,8,8,[0,0,0,0,0,0,0,0,1,1,2,0,2,1,0,1],"10.1097/TP.0000000000001747"],[28403995,"Comparative efficacy of pharmacological strategies for management of type 1 hepatorenal syndrome: a systematic review and network meta-analysis.","Lancet Gastroenterol Hepatol",2017,"Facciorusso et al.",0,[4,8],[15.17,0.0],15.17,8,8,8,[0,0,0,0,0,0,0,2,0,1,1,0,1,2,1,0],"10.1016/S2468-1253(16)30157-1"],[28479372,"A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta-analysis.","Lancet Gastroenterol Hepatol",2017,"Dossa et al.",0,[1,4],[15.17,15.17],15.17,10,8,8,[0,0,0,0,0,0,0,2,0,1,1,0,0,2,2,2],"10.1016/S2468-1253(17)30074-2"],[28735855,"Dementia prevention, intervention, and care.","Lancet",2017,"Livingston et al.",6,[5,6],[6.2,6.2],15.17,9,8,8,[0,0,0,0,0,0,0,1,2,2,0,0,1,1,1,0],"10.1016/S0140-6736(17)31363-6"],[28838644,"Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial.","Lancet Gastroenterol Hepatol",2017,"Ponsioen et al.",2,[4],[15.17],15.17,9,8,8,[0,0,0,0,0,0,0,1,0,1,1,1,0,3,2,0],"10.1016/S2468-1253(17)30248-0"],[28902580,"Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke.","N Engl J Med",2017,"Søndergaard et al.",2,[0,5,17],[15.17,15.17,10.83],15.17,9,8,9,[0,0,0,0,0,0,0,2,2,2,1,1,1,0,0,0],"10.1056/NEJMoa1707404"],[28902590,"Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.","N Engl J Med",2017,"Saver et al.",2,[0,5,17],[15.17,12.63,10.83],15.17,9,8,9,[0,0,0,0,0,0,0,2,2,2,0,1,1,1,0,0],"10.1056/NEJMoa1610057"],[29030361,"Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study.","Ann Rheum Dis",2018,"Mariette et al.",3,[14],[8.47],15.17,9,8,8,[0,0,0,0,0,0,0,0,0,1,2,1,1,1,2,0],"10.1136/annrheumdis-2017-212196"],[29174580,"A Systematic Review and Meta-analysis Comparing the Efficacy of Nonsteroidal Anti-inflammatory Drugs, Opioids, and Paracetamol in the Treatment of Acute Renal Colic.","Eur Urol",2018,"Pathan et al.",0,[8],[4.04],15.17,8,8,8,[0,0,0,0,0,0,0,0,0,1,0,2,1,1,2,1],"10.1016/j.eururo.2017.11.001"],[29626068,"Clinical Benefit of Evolocumab by Severity and Extent of Coronary Artery Disease: Analysis From FOURIER.","Circulation",2018,"Sabatine et al.",2,[0],[15.17],15.17,14,10,7,[0,0,0,0,0,0,0,0,3,0,1,2,1,0,2,1],"10.1161/CIRCULATIONAHA.118.034309"],[29685932,"Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.","Circulation",2018,"Evangelista et 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The Duration of Anticoagulation Trial Study Group.","N Engl J Med",1997,"Schulman et al.",2,[0,3,11],[15.12,10.68,0.0],15.12,10,8,7,[1,1,1,2,0,1,0,0,1,1,2,0,0,0,0,0],"10.1056/NEJM199702063360601"],[9703524,"Mother to child transmission of hepatitis C virus: prospective study of risk factors and timing of infection in children born to women seronegative for HIV-1. Tuscany Study Group on Hepatitis C Virus Infection.","BMJ",1998,"Resti et al.",5,[2,4],[15.12,9.02],15.12,9,8,7,[0,2,1,1,0,0,1,0,1,1,1,1,0,0,0,0],"10.1136/bmj.317.7156.437"],[9794737,"Home blood pressure measurement has a stronger predictive power for mortality than does screening blood pressure measurement: a population-based observation in Ohasama, Japan.","J Hypertens",1998,"Ohkubo et al.",5,[0],[15.12],15.12,8,8,7,[0,1,1,0,1,0,0,1,1,1,0,0,0,1,0,1],"10.1097/00004872-199816070-00010"],[10802351,"Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05.","Int J Radiat Oncol Biol Phys",2000,"Shaw et al.",3,[1,5],[15.12,10.26],15.12,10,8,7,[0,0,0,1,1,1,1,0,0,1,1,2,0,0,2,0],"10.1016/s0360-3016(99)00507-6"],[10979796,"Alendronate for the treatment of osteoporosis in men.","N Engl J Med",2000,"Orwoll et al.",2,[13,7],[15.12,14.28],15.12,9,8,7,[0,1,0,0,1,1,1,1,0,0,0,1,0,2,1,0],"10.1056/NEJM200008313430902"],[11041398,"Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study.","Lancet",2000,"Gatzoulis et al.",3,[0,17],[15.12,6.16],15.12,15,10,6,[0,1,1,1,2,0,0,0,2,0,0,2,0,1,0,1],"10.1016/S0140-6736(00)02714-8"],[11176812,"One-year survival following early revascularization for cardiogenic shock.","JAMA",2001,"Hochman et al.",2,[0],[15.12],15.12,19,10,6,[2,3,3,1,0,0,1,1,0,0,0,0,0,0,1,1],"10.1001/jama.285.2.190"],[11807679,"Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis.","Clin Infect Dis",2002,"Denning et al.",3,[2],[12.65],15.12,8,8,7,[1,0,0,1,0,1,1,1,1,0,0,1,0,0,1,0],"10.1086/324620"],[12103285,"Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial.","Lancet",2002,"Lacy et al.",2,[1,4],[9.48,11.84],15.12,10,8,6,[1,1,2,0,0,0,2,0,0,1,0,1,1,0,1,0],"10.1016/S0140-6736(02)09290-5"],[12243916,"Primary angioplasty versus prehospital fibrinolysis in acute myocardial infarction: a randomised study.","Lancet",2002,"Bonnefoy et al.",2,[0],[15.12],15.12,13,10,6,[1,1,1,1,3,0,0,2,1,0,0,0,0,1,0,0],"10.1016/S0140-6736(02)09963-4"],[12394945,"Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, randomized trial.","Crit Care Med",2002,"Bouman et al.",2,[8],[9.77],15.12,14,8,8,[1,0,3,1,0,0,1,1,1,1,0,0,0,0,1,0],"10.1097/00003246-200210000-00005"],[12444180,"Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus.","N Engl J Med",2002,"Hulscher et al.",2,[1,4],[15.12,15.12],15.12,11,8,8,[2,0,1,1,0,0,0,0,1,0,1,2,0,1,0,1],"10.1056/NEJMoa022343"],[12817109,"The ACCESS Study: evaluation of Acute Candesartan Cilexetil Therapy in Stroke Survivors.","Stroke",2003,"Schrader et al.",2,[0,5],[15.12,8.37],15.12,12,8,7,[1,1,2,1,0,0,0,1,1,0,0,0,0,1,0,2],"10.1161/01.STR.0000075777.18006.89"],[14044222,"STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION.","JAMA",1963,"KATZ et al.",7,[6],[0.0],15.12,10,8,8,[1,1,1,0,0,1,1,0,0,0,1,0,1,1,0,0],"10.1001/jama.1963.03060120024016"],[14399272,"A rating scale for depression.","J Neurol Neurosurg Psychiatry",1960,"HAMILTON",7,[6],[12.65],15.12,8,8,7,[1,1,1,1,1,1,0,1,0,0,0,0,1,0,0,0],"10.1136/jnnp.23.1.56"],[14500804,"The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.","N Engl J Med",2003,"Black et al.",2,[7,13],[15.12,15.12],15.12,10,8,7,[2,0,1,0,1,1,2,0,1,1,0,0,0,0,0,1],"10.1056/NEJMoa031975"],[14526151,"A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHE II > or =6).","Pancreatology",2003,"Gupta et 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al.",5,[0],[15.12],15.12,9,8,7,[1,1,0,1,1,2,1,1,0,1,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.107.740597"],[19001495,"Efficacy of statins in familial hypercholesterolaemia: a long term cohort study.","BMJ",2008,"Versmissen et al.",5,[7,0,17],[14.28,5.78,6.77],15.12,13,8,7,[1,0,1,0,0,1,1,1,2,0,1,0,0,0,0,1],"10.1136/bmj.a2423"],[19005195,"General and abdominal adiposity and risk of death in Europe.","N Engl J Med",2008,"Pischon et al.",7,[7],[12.65],15.12,12,8,9,[1,1,0,1,1,1,0,0,0,1,1,0,0,0,1,0],"10.1056/NEJMoa0801891"],[19160191,"Antimicrobial prophylaxis for colorectal surgery.","Cochrane Database Syst Rev",2009,"Nelson et al.",0,[2],[9.02],15.12,14,8,8,[1,1,2,1,0,0,1,0,1,1,0,0,0,1,0,0],"10.1002/14651858.CD001181.pub3"],[19602453,"Complications associated with double balloon enteroscopy at nine US centers.","Clin Gastroenterol Hepatol",2009,"Gerson et al.",5,[4],[15.12],15.12,11,8,7,[1,1,0,0,0,1,1,2,0,0,1,0,0,0,1,1],"10.1016/j.cgh.2009.07.005"],[19608798,"The efficacy of an intraoperative 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review and meta-analysis.","Gut",2019,"Vijayvargiya et al.",0,[4],[12.13],14.95,10,10,8,[0,0,0,0,0,0,0,0,0,0,1,3,0,0,5,1],"10.1136/gutjnl-2018-316405"],[37139824,"American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults.","J Am Geriatr Soc",2023,"By the 2023 American Geriatrics Society ",7,[],[],14.95,10,10,8,[0,0,0,0,0,0,0,0,0,0,0,0,1,3,4,2],"10.1111/jgs.18372"],[19329820,"Coronary bypass surgery with or without surgical ventricular reconstruction.","N Engl J Med",2009,"Jones et al.",2,[0],[14.94],14.94,15,11,6,[0,3,1,2,0,0,0,0,2,0,2,1,0,0,0,0],"10.1056/NEJMoa0900559"],[11832465,"A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease.","Gastroenterology",2002,"Sandborn et al.",6,[4],[14.92],14.92,10,10,6,[1,1,1,0,0,0,3,1,1,0,0,0,0,0,2,0],"10.1053/gast.2002.31072"],[12600913,"Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease.","Circulation",2003,"Hoffman et al.",2,[0,17],[14.92,4.65],14.92,11,10,7,[0,0,1,2,1,3,1,0,0,0,0,0,0,0,1,1],"10.1161/01.cir.0000051365.81920.28"],[16287954,"High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial.","JAMA",2005,"Pedersen et al.",2,[0],[13.4],14.92,36,16,6,[4,5,1,6,0,1,0,0,2,0,0,0,1,0,0,0],"10.1001/jama.294.19.2437"],[18840879,"Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study.","Eur Heart J",2008,"Neil et al.",7,[7,17,0],[13.55,6.84,3.74],14.92,16,10,8,[2,1,3,1,1,0,0,1,0,0,1,0,0,0,0,0],"10.1093/eurheartj/ehn422"],[20578829,"Early removal of central venous catheter in patients with candidemia does not improve outcome: analysis of 842 patients from 2 randomized clinical trials.","Clin Infect Dis",2010,"Nucci et al.",2,[2],[14.92],14.92,13,10,7,[1,2,3,1,1,1,0,0,0,0,0,0,0,0,0,1],"10.1086/653935"],[22508468,"A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: the treatment of Early Aggressive Rheumatoid Arthritis Trial.","Arthritis Rheum",2012,"Moreland et al.",2,[11],[14.92],14.92,13,10,6,[0,0,0,2,2,1,1,0,2,0,1,0,0,1,0,0],"10.1002/art.34498"],[25064741,"Statewide regionalization of postarrest care for out-of-hospital cardiac arrest: association with survival and neurologic outcome.","Ann Emerg Med",2014,"Spaite et al.",5,[0],[14.92],14.92,13,10,6,[0,0,0,0,5,0,0,0,1,1,2,0,0,1,1,1],"10.1016/j.annemergmed.2014.05.028"],[3782631,"Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin.","J Am Coll Cardiol",1986,"Canner et al.",3,[0],[9.83],14.91,26,12,6,[5,4,0,4,1,1,0,0,1,0,0,0,0,0,0,0],"10.1016/s0735-1097(86)80293-5"],[11113085,"Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial.","Gastroenterology",2000,"Akriviadis et al.",2,[4],[14.88],14.88,10,10,7,[0,2,2,0,0,0,0,3,0,2,0,0,0,1,0,0],"10.1053/gast.2000.20189"],[19573904,"Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial.","Lancet",2009,"Jabre et al.",2,[7],[1.0],14.88,15,10,8,[0,4,2,0,0,0,3,0,0,2,0,0,0,0,0,1],"10.1016/S0140-6736(09)60949-1"],[28855115,"Catheter Ablation Versus Medical Rate Control in Atrial Fibrillation and Systolic Dysfunction: The CAMERA-MRI Study.","J Am Coll Cardiol",2017,"Prabhu et al.",2,[0],[14.88],14.88,12,10,7,[0,0,0,0,0,0,0,1,1,1,0,3,0,5,0,0],"10.1016/j.jacc.2017.08.041"],[32888407,"Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study.","Lancet",2020,"Abramson et al.",3,[1,10],[14.86,14.86],14.86,11,11,7,[0,0,0,0,0,0,0,0,0,0,0,2,3,1,3,2],"10.1016/S0140-6736(20)31366-0"],[10717011,"Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group.","N Engl J Med",2000,"Lovell et al.",2,[11],[12.95],14.84,11,9,7,[1,2,0,0,0,0,0,0,2,0,0,1,0,0,2,1],"10.1056/NEJM200003163421103"],[11677969,"Is submucosal epinephrine injection necessary before polypectomy? A prospective, comparative study.","Hepatogastroenterology",2001,"Hsieh et al.",2,[4,1],[14.84,12.32],14.84,9,9,7,[1,4,1,1,1,0,0,0,0,0,0,0,0,1,0,0],""],[15136667,"Assessment: transcranial Doppler ultrasonography: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.","Neurology",2004,"Sloan et al.",7,[0,5,17],[11.58,10.86,0.0],14.84,9,9,7,[2,3,1,1,0,0,0,1,0,0,0,0,1,0,0,0],"10.1212/wnl.62.9.1468"],[15528283,"A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis.","Ann Rheum Dis",2005,"Fraser et al.",2,[14,11,13],[14.84,10.26,10.26],14.84,10,9,7,[0,1,1,0,0,2,1,2,2,0,0,0,0,0,0,0],"10.1136/ard.2004.024463"],[15740535,"Severe haemorrhage following abdominal paracentesis for ascites in patients with liver disease.","Aliment Pharmacol Ther",2005,"Pache et al.",5,[4],[14.84],14.84,10,9,7,[0,0,1,0,0,0,1,2,0,0,3,0,0,0,1,1],"10.1111/j.1365-2036.2005.02387.x"],[15939837,"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication.","Arch Gen Psychiatry",2005,"Kessler et al.",5,[6],[10.52],14.84,9,9,7,[0,1,0,2,0,1,2,0,0,2,0,0,0,1,0,0],"10.1001/archpsyc.62.6.593"],[16279903,"Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: the ASCEND II trial.","Am J Gastroenterol",2005,"Hanauer et al.",2,[4],[14.84],14.84,10,9,7,[1,2,0,0,2,0,2,1,0,0,0,0,0,0,1,0],"10.1111/j.1572-0241.2005.00248.x"],[16429354,"Double-balloon enteroscopy: indications, diagnostic yield, and complications in a series of 275 patients with suspected small-bowel disease.","Endoscopy",2006,"Heine et al.",5,[4],[14.84],14.84,9,9,7,[0,1,1,1,3,0,2,0,0,0,0,0,0,1,0,0],"10.1055/s-2005-921188"],[16625136,"Impact of systematic evaluation of pain and agitation in an intensive care unit.","Crit Care Med",2006,"Chanques et al.",2,[5],[9.17],14.84,10,9,7,[0,0,3,2,1,0,0,1,0,0,0,1,0,1,0,0],"10.1097/01.CCM.0000218416.62457.56"],[17326221,"Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: final long-term results.","Liver Transpl",2007,"Schiff et al.",3,[4,2],[12.32,10.16],14.84,10,9,7,[0,3,1,1,0,3,0,0,0,0,1,0,0,1,0,0],"10.1002/lt.20981"],[17765406,"Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer.","Int J Radiat Oncol Biol Phys",2008,"Kuban et al.",2,[1,8,9],[14.84,14.84,14.84],14.84,10,9,7,[0,2,3,2,1,0,1,0,0,0,0,0,0,1,0,0],"10.1016/j.ijrobp.2007.06.054"],[18362235,"Interrelation of coronary calcification, myocardial ischemia, and outcomes in patients with intermediate likelihood of coronary artery disease: a combined positron emission tomography/computed tomography study.","Circulation",2008,"Schenker et al.",5,[0,7],[14.84,1.0],14.84,10,9,7,[2,0,1,0,0,1,0,0,0,0,0,3,1,1,0,0],"10.1161/CIRCULATIONAHA.107.717512"],[18840838,"Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis: a randomized controlled trial.","JAMA",2008,"Bernardi et al.",2,[0],[14.84],14.84,9,9,7,[1,2,0,0,0,0,0,0,1,1,3,0,0,0,1,0],"10.1001/jama.300.14.1653"],[19443635,"Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes.","J Am Soc Nephrol",2009,"Ninomiya et al.",7,[8,7,0],[11.05,7.47,2.0],14.84,13,9,8,[0,1,3,1,0,0,0,0,1,2,0,0,0,1,0,0],"10.1681/ASN.2008121270"],[19671933,"Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration.","BMJ",2009,"Stone et al.",0,[6],[10.52],14.84,9,9,7,[0,3,2,1,1,0,1,0,0,0,0,0,1,0,0,0],"10.1136/bmj.b2880"],[20647200,"Multicenter, placebo-controlled trial of lorcaserin for weight management.","N Engl J Med",2010,"Smith et al.",2,[7],[12.95],14.84,9,9,7,[0,0,1,1,2,1,2,2,0,0,0,0,0,0,0,0],"10.1056/NEJMoa0909809"],[20801608,"Prospective randomized trial comparing endovenous laser ablation and surgery for treatment of primary great saphenous varicose veins with a 2-year follow-up.","J Vasc Surg",2010,"Christenson et al.",2,[0],[14.84],14.84,9,9,7,[1,0,0,1,2,1,0,0,0,2,0,0,2,0,0,0],"10.1016/j.jvs.2010.06.104"],[20824872,"Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy.","Cochrane Database Syst Rev",2010,"Woudstra et al.",0,[9],[9.17],14.84,10,9,7,[0,0,0,0,0,2,0,1,2,1,0,2,1,0,0,0],"10.1002/14651858.CD008148.pub2"],[21200183,"The Five-Factor Score revisited: assessment of prognoses of systemic necrotizing vasculitides based on the French Vasculitis Study Group (FVSG) cohort.","Medicine (Baltimore)",2011,"Guillevin et al.",7,[0,11],[14.84,14.84],14.84,11,9,7,[0,0,1,0,1,0,0,0,0,1,2,0,1,0,3,0],"10.1097/MD.0b013e318205a4c6"],[21560194,"Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification.","Inflamm Bowel Dis",2011,"Levine et al.",7,[4],[14.84],14.84,9,9,7,[0,1,1,1,0,0,0,3,0,0,0,0,0,2,1,0],"10.1002/ibd.21493"],[21596680,"Timing of initiation of antiretroviral therapy in human immunodeficiency virus (HIV)--associated tuberculous meningitis.","Clin Infect Dis",2011,"Török et al.",2,[2,9,12],[14.84,5.93,5.93],14.84,10,9,7,[0,3,2,0,0,1,1,0,2,0,0,0,0,0,0,1],"10.1093/cid/cir230"],[21788587,"Sports-related sudden death in the general population.","Circulation",2011,"Marijon et al.",5,[0],[12.32],14.84,12,9,7,[0,0,0,1,0,3,1,1,0,0,0,0,0,2,0,1],"10.1161/CIRCULATIONAHA.110.008979"],[22004479,"Late evening snack: exploiting a period of anabolic opportunity in cirrhosis.","J Gastroenterol Hepatol",2012,"Tsien et al.",6,[4,5],[14.84,5.78],14.84,12,9,7,[0,0,0,1,0,0,0,0,2,2,1,0,0,1,3,0],"10.1111/j.1440-1746.2011.06951.x"],[22018121,"Unintended pregnancy in the United States: incidence and disparities, 2006.","Contraception",2011,"Finer et al.",7,[9,2],[4.04,2.0],14.84,9,9,7,[0,1,2,3,0,1,1,0,0,0,0,0,0,0,0,1],"10.1016/j.contraception.2011.07.013"],[22215856,"Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial.","Circulation",2012,"Hohnloser et al.",2,[0],[14.84],14.84,11,9,7,[0,3,1,1,1,3,0,1,0,0,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.111.055970"],[22998715,"Mortality after surgery in Europe: a 7 day cohort study.","Lancet",2012,"Pearse et al.",5,[0],[6.2],14.84,9,9,7,[0,0,0,0,1,0,2,0,0,0,0,2,0,2,1,1],"10.1016/S0140-6736(12)61148-9"],[23100493,"Outpatient versus inpatient treatment in patients with pulmonary embolism: a meta-analysis.","Eur Respir J",2013,"Zondag et al.",0,[0,3],[14.84,11.58],14.84,11,9,7,[0,0,0,1,0,2,1,2,0,1,3,0,0,0,0,0],"10.1183/09031936.00093712"],[23498675,"CMR imaging predicts death and other adverse events in suspected cardiac sarcoidosis.","JACC Cardiovasc Imaging",2013,"Greulich et al.",5,[0,10,12],[12.95,4.65,4.65],14.84,14,9,7,[0,0,0,0,0,0,0,1,2,2,2,1,0,1,0,0],"10.1016/j.jcmg.2012.10.021"],[24461613,"Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study.","Lancet Respir Med",2013,"Decramer et al.",2,[3],[14.84],14.84,10,9,7,[0,0,0,0,1,1,4,0,0,0,2,1,0,0,1,0],"10.1016/S2213-2600(13)70158-9"],[25461851,"Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States.","Gastroenterology",2015,"Wong et al.",7,[4,1,7],[14.84,1.0,0.0],14.84,9,9,7,[0,0,0,0,0,0,2,1,2,1,2,0,1,0,0,0],"10.1053/j.gastro.2014.11.039"],[25628372,"Ovarian cancer risk after salpingectomy: a nationwide population-based study.","J Natl Cancer Inst",2015,"Falconer et al.",5,[9,1,7],[12.95,10.86,9.17],14.84,9,9,7,[0,0,0,0,1,1,2,2,0,0,0,0,0,1,2,0],"10.1093/jnci/dju410"],[26255043,"Diet low in FODMAPs reduces symptoms of irritable bowel syndrome as well as traditional dietary advice: a randomized controlled trial.","Gastroenterology",2015,"Böhn et al.",2,[4],[14.84],14.84,10,9,8,[0,0,0,0,0,1,1,1,0,0,3,1,2,0,0,0],"10.1053/j.gastro.2015.07.054"],[26731686,"Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness, symptoms of vulvovaginal atrophy, and of the genitourinary syndrome of menopause.","Menopause",2016,"Labrie et al.",2,[9,6,8],[11.58,2.69,2.0],14.84,13,9,7,[0,0,0,0,0,1,2,2,1,0,3,0,0,1,0,0],"10.1097/GME.0000000000000571"],[26886521,"Effects of Testosterone Treatment in Older Men.","N Engl J Med",2016,"Snyder et al.",2,[7],[8.47],14.84,11,11,6,[0,0,0,0,0,3,2,3,1,0,0,1,0,1,0,0],"10.1056/NEJMoa1506119"],[26921136,"Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial.","Lancet",2016,"Norman et al.",2,[9],[12.95],14.84,10,9,7,[0,0,0,0,0,0,3,0,1,1,0,1,0,2,0,1],"10.1016/S0140-6736(16)00350-0"],[27533160,"Acute Aortic Dissection and Intramural Hematoma: A Systematic Review.","JAMA",2016,"Mussa et al.",1,[0],[14.84],14.84,12,9,8,[0,0,0,0,0,0,0,0,0,2,1,3,2,1,1,0],"10.1001/jama.2016.10026"],[27690741,"Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.","N Engl J Med",2016,"Simpson et al.",2,[14,12,17],[14.84,12.95,10.52],14.84,12,9,7,[0,0,0,0,0,0,0,0,0,0,1,3,1,2,4,1],"10.1056/NEJMoa1610020"],[28166390,"Emollients and moisturisers for eczema.","Cochrane Database Syst Rev",2017,"van Zuuren et al.",0,[14],[12.95],14.84,10,9,7,[0,0,0,0,0,0,0,0,1,0,0,2,1,2,3,1],"10.1002/14651858.CD012119.pub2"],[28258178,"International criteria for electrocardiographic interpretation in athletes: Consensus statement.","Br J Sports Med",2017,"Drezner et al.",4,[0],[14.84],14.84,9,9,7,[0,0,0,0,0,0,1,0,1,0,1,0,0,2,2,2],"10.1136/bjsports-2016-097331"],[28291393,"Early Positron Emission Tomography Response-Adapted Treatment in Stage I and II Hodgkin Lymphoma: Final Results of the Randomized EORTC/LYSA/FIL H10 Trial.","J Clin Oncol",2017,"André et al.",2,[1,10],[12.95,12.95],14.84,9,9,7,[0,0,0,0,0,0,0,2,1,0,0,1,0,3,1,1],"10.1200/JCO.2016.68.6394"],[28989060,"Metroticket 2.0 Model for Analysis of Competing Risks of Death After Liver Transplantation for Hepatocellular Carcinoma.","Gastroenterology",2018,"Mazzaferro et al.",5,[1,4],[10.83,14.84],14.84,10,9,7,[0,0,0,0,0,0,0,0,0,0,1,1,1,5,1,1],"10.1053/j.gastro.2017.09.025"],[29045547,"Safety of resuming anti-PD-1 in patients with immune-related adverse events (irAEs) during combined anti-CTLA-4 and anti-PD1 in metastatic melanoma.","Ann Oncol",2018,"Pollack et al.",5,[1,14],[11.58,3.25],14.84,9,9,7,[0,0,0,0,0,0,0,1,1,4,1,1,0,1,0,0],"10.1093/annonc/mdx642"],[29268948,"Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial.","Lancet",2018,"Powles et al.",2,[1,8],[14.84,12.95],14.84,11,9,8,[0,0,0,0,0,0,0,1,2,2,2,2,0,0,2,0],"10.1016/S0140-6736(17)33297-X"],[30266309,"Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Clinical Trial: Data from the HORRAD Trial.","Eur Urol",2019,"Boevé et al.",2,[1,8,9],[14.84,14.84,13.38],14.84,12,9,7,[0,0,0,0,0,0,0,0,0,3,3,3,0,1,1,1],"10.1016/j.eururo.2018.09.008"],[30342843,"Prognostic Value of Biochemical Recurrence Following Treatment with Curative Intent for Prostate Cancer: A Systematic Review.","Eur Urol",2019,"Van den Broeck et al.",1,[1,8,9],[14.84,12.95,12.95],14.84,12,9,7,[0,0,0,0,0,0,0,0,0,2,2,2,1,4,0,1],"10.1016/j.eururo.2018.10.011"],[30688979,"Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial.","JAMA",2019,"Williamson et al.",2,[6,0,5],[3.25,9.17,3.74],14.84,14,9,7,[0,0,0,0,0,0,0,0,1,1,1,0,0,1,4,1],"10.1001/jama.2018.21442"],[30700139,"Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association.","Circulation",2019,"Benjamin et al.",7,[0,5],[14.84,2.69],14.84,12,9,7,[0,0,0,0,0,0,0,0,0,1,1,3,1,2,2,0],"10.1161/CIR.0000000000000659"],[31543428,"Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.","Lancet",2019,"Bachert et al.",2,[3,16,2],[12.95,7.97,9.77],14.84,11,9,8,[0,0,0,0,0,0,0,0,0,0,1,1,2,2,2,3],"10.1016/S0140-6736(19)31881-1"],[32524991,"Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.","J Allergy Clin Immunol",2020,"Gevaert et al.",2,[3,16,2],[12.95,7.97,9.77],14.84,11,9,8,[0,0,0,0,0,0,0,0,0,0,1,1,2,2,1,4],"10.1016/j.jaci.2020.05.032"],[32628791,"Helicobacter pylori eradication for the prevention of gastric neoplasia.","Cochrane Database Syst Rev",2020,"Ford et al.",0,[2,4,1],[2.69,14.84,12.32],14.84,9,9,7,[0,0,0,0,0,0,0,0,0,0,1,1,1,1,3,2],"10.1002/14651858.CD005583.pub3"],[14698338,"Transient elastography: a new noninvasive method for assessment of hepatic fibrosis.","Ultrasound Med Biol",2003,"Sandrin et al.",7,[4,2],[14.8,3.1],14.8,11,10,5,[1,0,0,2,1,1,0,0,1,0,1,0,1,1,1,1],"10.1016/j.ultrasmedbio.2003.07.001"],[33580789,"EU-Wide Cross-Sectional Observational Study of Lipid-Modifying Therapy Use in Secondary and Primary Care: the DA VINCI study.","Eur J Prev Cardiol",2021,"Ray et al.",5,[0,7],[10.43,5.29],14.78,11,10,8,[0,0,0,0,0,0,0,0,0,0,0,0,1,5,2,3],"10.1093/eurjpc/zwaa047"],[35644166,"Upadacitinib as induction and maintenance therapy for moderately to severely active ulcerative colitis: results from three phase 3, multicentre, double-blind, randomised trials.","Lancet",2022,"Danese et al.",2,[4,14,2],[13.09,1.0,0.0],14.78,10,10,8,[0,0,0,0,0,0,0,0,0,0,0,0,1,3,4,2],"10.1016/S0140-6736(22)00581-5"],[9096989,"Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S).","Diabetes Care",1997,"Pyŏrälä et al.",2,[0,7],[9.15,11.89],14.77,13,9,6,[2,1,1,3,2,0,0,0,1,2,0,0,0,0,0,1],"10.2337/diacare.20.4.614"],[12431967,"Prognostic factors for relapse in stage I seminoma managed by surveillance: a pooled analysis.","J Clin Oncol",2002,"Warde et al.",7,[1,7,8],[14.77,14.77,14.77],14.77,11,9,7,[2,1,1,0,0,1,1,2,0,1,0,0,0,0,2,0],"10.1200/JCO.2002.01.038"],[12767651,"Amiodarone versus implantable cardioverter-defibrillator:randomized trial in patients with nonischemic dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia--AMIOVIRT.","J Am Coll Cardiol",2003,"Strickberger et al.",2,[0,17],[14.77,0.0],14.77,14,9,6,[0,0,1,1,2,0,1,1,1,0,0,1,1,0,0,0],"10.1016/s0735-1097(03)00297-3"],[15690481,"Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C.","Hepatology",2005,"Ziol et al.",5,[4,2],[14.77,4.65],14.77,10,9,6,[1,1,0,1,1,2,1,0,0,0,1,0,0,2,0,0],"10.1002/hep.20506"],[23266597,"Discerning the incidence of symptomatic and asymptomatic episodes of atrial fibrillation before and after catheter ablation (DISCERN AF): a prospective, multicenter study.","JAMA Intern Med",2013,"Verma et al.",5,[0],[14.77],14.77,16,9,6,[0,1,0,3,0,2,1,1,0,1,1,0,0,2,0,0],"10.1001/jamainternmed.2013.1561"],[25140956,"Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia.","N Engl J Med",2014,"DeBaun et al.",2,[10,0,17],[11.5,6.16,6.77],14.77,10,9,6,[0,0,0,2,1,1,0,2,1,1,0,0,0,1,0,1],"10.1056/NEJMoa1401731"],[28564682,"Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality: A Systematic Review and Network Meta-analysis.","JAMA Cardiol",2017,"Bundy et al.",0,[0],[13.93],14.77,21,13,5,[0,0,0,0,0,0,1,1,3,1,2,0,1,2,3,0],"10.1001/jamacardio.2017.1421"],[11279730,"Exercise-based rehabilitation for coronary heart disease.","Cochrane 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al.",5,[4,2],[12.32,5.39],14.7,11,10,7,[0,0,0,0,0,0,0,0,0,0,2,0,1,3,3,2],"10.1053/j.gastro.2017.04.044"],[30576643,"Factors Associated with Survival of Patients With Severe Acute-On-Chronic Liver Failure Before and After Liver Transplantation.","Gastroenterology",2019,"Sundaram et al.",5,[4],[14.7],14.7,10,10,7,[0,0,0,0,0,0,0,0,0,0,1,1,2,5,1,0],"10.1053/j.gastro.2018.12.007"],[30768988,"Validation of Baveno VI Criteria for Screening and Surveillance of Esophageal Varices in Patients With Compensated Cirrhosis and a Sustained Response to Antiviral Therapy.","Gastroenterology",2019,"Thabut et al.",7,[4],[14.7],14.7,10,10,7,[0,0,0,0,0,0,0,0,0,1,0,3,1,4,1,0],"10.1053/j.gastro.2018.11.053"],[33197396,"Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial.","Lancet",2020,"Yannopoulos et 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al.",5,[0],[3.25],14.66,13,9,11,[0,0,1,0,2,0,0,0,1,2,0,0,0,3,0,1],"10.1056/NEJMoa1003833"],[22663011,"Improved survival with MEK inhibition in BRAF-mutated melanoma.","N Engl J Med",2012,"Flaherty et al.",2,[1,14],[14.66,12.15],14.66,11,9,7,[0,2,2,1,0,2,1,0,3,0,0,0,0,0,0,0],"10.1056/NEJMoa1203421"],[22735384,"Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial.","Lancet",2012,"Hauschild et al.",2,[1,14],[14.66,12.76],14.66,10,9,7,[0,1,2,2,0,3,0,0,1,0,0,0,0,0,0,1],"10.1016/S0140-6736(12)60868-X"],[23183941,"Effect of statins on skeletal muscle function.","Circulation",2013,"Parker et al.",2,[13],[1.0],14.66,15,9,7,[0,0,1,3,0,2,0,0,2,0,0,0,0,1,0,1],"10.1161/CIRCULATIONAHA.112.136101"],[25015340,"Prognostic value of fasting versus nonfasting low-density lipoprotein cholesterol levels on long-term mortality: insight from the National Health and Nutrition Examination Survey III (NHANES-III).","Circulation",2014,"Doran et 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cirrhosis: a multivariate analysis of prognostic factors of tumor growth rate and patient survival.","Hepatology",1992,"Barbara et al.",5,[4,1],[14.63,11.38],14.63,11,8,9,[0,2,1,0,1,1,0,0,1,0,0,2,1,0,0,0],"10.1002/hep.1840160122"],[1863023,"Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.","Ann Intern Med",1991,"D'Alonzo et al.",5,[0,3],[12.65,13.27],14.63,8,8,7,[2,1,0,1,1,0,0,1,1,0,0,0,0,0,1,0],"10.7326/0003-4819-115-5-343"],[1969518,"Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias.","Lancet",1990,"MacMahon et al.",3,[0,5],[10.68,1.35],14.63,19,8,9,[1,2,1,2,1,0,0,0,0,0,0,1,0,0,0,1],"10.1016/0140-6736(90)90878-9"],[2022152,"The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC).","Dis Colon Rectum",1991,"Vasen et al.",7,[1,4],[14.63,12.16],14.63,11,8,10,[0,1,1,1,1,0,1,0,2,0,0,0,0,0,0,1],"10.1007/BF02053699"],[2034244,"Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer.","N Engl J Med",1991,"Wolf et al.",2,[1,16,3],[14.63,6.77,4.65],14.63,8,8,7,[0,0,1,0,1,2,0,1,0,1,0,1,0,0,1,0],"10.1056/NEJM199106133242402"],[2178534,"Very low doses of warfarin can prevent thrombosis in central venous catheters. A randomized prospective trial.","Ann Intern Med",1990,"Bern et al.",2,[0],[10.26],14.63,8,8,7,[2,0,1,1,1,0,1,0,0,0,0,0,0,1,0,1],"10.7326/0003-4819-76-3-112-6-423"],[2737595,"Prognosis in primary biliary cirrhosis: model for decision making.","Hepatology",1989,"Dickson et al.",7,[4],[12.16],14.63,8,8,7,[0,0,0,0,1,0,0,2,1,1,0,1,0,1,0,1],"10.1002/hep.1840100102"],[3495732,"Successful intermittent chemoprophylaxis for Pneumocystis carinii pneumonitis.","N Engl J Med",1987,"Hughes et al.",2,[2,3],[9.02,4.65],14.63,9,8,7,[1,2,1,0,1,2,1,0,0,0,0,0,0,1,0,0],"10.1056/NEJM198706253162604"],[3533203,"Effect of early blood transfusion on gastrointestinal haemorrhage.","Br J Surg",1986,"Blair et al.",2,[10,4],[3.1,11.38],14.63,9,8,7,[0,2,1,0,0,2,0,0,1,1,1,0,1,0,0,0],"10.1002/bjs.1800731007"],[4606955,"Prophylactic colchicine therapy of intercritical gout. A placebo-controlled study of probenecid-treated patients.","Arthritis Rheum",1974,"Paulus et al.",3,[7,11,17],[14.63,14.63,14.63],14.63,9,8,7,[1,1,1,0,0,0,2,0,0,1,0,1,1,0,0,0],"10.1002/art.1780170517"],[4703316,"Medical assessment by a Delphi group opinion technic.","N Engl J Med",1973,"Milholland et al.",7,[13],[1.0],14.63,8,8,7,[0,1,2,0,0,1,0,0,1,0,1,0,0,1,0,1],"10.1056/NEJM197306142882405"],[7903776,"Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis?","Lancet",1994,"Bernstein et al.",5,[4,1],[14.63,6.84],14.63,11,8,9,[1,0,2,1,3,0,0,0,0,0,1,0,1,1,0,0],"10.1016/s0140-6736(94)90813-3"],[7905143,"Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group.","Lancet",1994,"",6,[0],[14.63],14.63,21,10,6,[3,5,3,1,0,1,1,1,0,0,0,0,0,0,0,0],""],[7935634,"Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries.","N Engl J Med",1994,"Bickell et al.",3,[13,0],[5.08,5.08],14.63,12,10,6,[0,0,0,0,3,0,1,1,0,0,0,1,2,0,2,1],"10.1056/NEJM199410273311701"],[8569016,"Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI Trial.","JAMA",1996,"",2,[9],[5.78],14.63,8,8,7,[1,0,2,0,1,0,1,0,0,0,1,0,0,1,1,0],"10.1001/jama.1996.03530290040035"],[8645855,"Intravascular catheter exchange and duration of candidemia. NIAID Mycoses Study Group and the Candidemia Study Group.","Clin Infect Dis",1995,"Rex et al.",3,[2],[14.63],14.63,9,8,7,[1,1,2,1,1,1,1,0,0,0,0,0,0,0,0,0],"10.1093/clinids/21.4.994"],[8815753,"Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial.","Ann Intern Med",1996,"Gourley et al.",2,[11,8],[14.63,12.16],14.63,9,8,7,[0,2,1,0,1,0,0,1,0,0,1,0,0,2,0,1],"10.7326/0003-4819-125-7-199610010-00003"],[9129544,"The probability of malignancy in solitary pulmonary nodules. Application to small radiologically indeterminate nodules.","Arch Intern Med",1997,"Swensen et al.",5,[3,1],[14.63,12.65],14.63,11,8,7,[0,0,2,2,0,1,1,0,0,1,1,0,1,0,0,0],""],[9235493,"A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection. The Syphilis and HIV Study Group.","N Engl J Med",1997,"Rolfs et al.",2,[2,9,12],[14.63,13.27,4.65],14.63,8,8,7,[1,0,1,0,1,1,0,0,0,0,2,1,0,1,0,0],"10.1056/NEJM199707313370504"],[9462221,"Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group.","Gut",1997,"Bellentani et al.",5,[4],[14.63],14.63,9,8,7,[0,2,1,1,1,1,1,0,0,2,0,0,0,0,0,0],"10.1136/gut.41.6.845"],[9516219,"Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.","N Engl J Med",1998,"Palella et al.",7,[2,12,9],[12.65,8.37,8.37],14.63,10,8,7,[1,1,1,3,0,2,0,0,1,0,1,0,0,0,0,0],"10.1056/NEJM199803263381301"],[9682700,"Early worsening of diabetic retinopathy in the Diabetes Control and Complications Trial.","Arch Ophthalmol",1998,"",2,[7,0,15],[12.65,7.58,5.08],14.63,11,8,7,[0,1,2,1,1,0,1,3,0,1,0,0,0,0,0,0],"10.1001/archopht.116.7.874"],[10092713,"Cincinnati Prehospital Stroke Scale: reproducibility and validity.","Ann Emerg Med",1999,"Kothari et al.",7,[0,5],[12.16,12.16],14.63,9,8,7,[0,1,2,0,1,0,0,1,1,0,0,1,0,0,1,0],"10.1016/s0196-0644(99)70299-4"],[10588963,"The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group.","N Engl J Med",1999,"Poldermans et al.",2,[0],[12.16],14.63,14,8,7,[2,2,1,1,1,0,2,0,1,0,0,0,0,0,0,0],"10.1056/NEJM199912093412402"],[10619727,"Candiduria: a randomized, double-blind study of treatment with fluconazole and placebo. The National Institute of Allergy and Infectious Diseases (NIAID) Mycoses Study Group.","Clin Infect Dis",2000,"Sobel et al.",2,[2,8],[12.16,6.77],14.63,8,8,7,[2,1,1,0,1,1,1,0,1,0,0,0,0,0,0,0],"10.1086/313580"],[10651654,"Colorectal cancer prevention in ulcerative colitis: a case-control study.","Aliment Pharmacol Ther",2000,"Eaden et al.",5,[4,1],[14.63,5.29],14.63,10,8,9,[1,0,2,1,2,0,0,0,0,0,2,0,1,1,0,0],"10.1046/j.1365-2036.2000.00698.x"],[10826454,"The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study Investigators.","Arch Intern Med",2000,"Lederle et al.",2,[0],[14.63],14.63,8,8,7,[1,0,2,0,0,1,1,1,1,0,0,0,1,0,0,0],"10.1001/archinte.160.10.1425"],[10882607,"Comparative efficacy and distribution of lipid formulations of amphotericin B in experimental Candida albicans infection of the central nervous system.","J Infect Dis",2000,"Groll et al.",7,[2,5],[14.63,0.0],14.63,8,8,6,[1,1,1,2,0,1,0,0,0,0,0,0,0,0,1,1],"10.1086/315643"],[10996576,"A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group.","Am J Med",2000,"Chesnut et al.",2,[13,7],[14.63,14.63],14.63,9,8,7,[2,0,1,1,0,1,0,0,1,2,0,1,0,0,0,0],"10.1016/s0002-9343(00)00490-3"],[11000340,"Effects of risedronate treatment on bone density and vertebral fracture in patients on corticosteroid therapy.","Calcif Tissue Int",2000,"Wallach et al.",2,[13,7],[14.63,13.81],14.63,9,8,7,[1,1,0,1,0,0,0,0,1,0,0,1,0,3,1,0],"10.1007/s002230001146"],[11115165,"Risk of developing a subsequent nonmelanoma skin cancer in patients with a history of nonmelanoma skin cancer: a critical review of the literature and meta-analysis.","Arch Dermatol",2000,"Marcil et al.",0,[1,14],[14.63,14.63],14.63,10,8,7,[0,0,0,2,1,1,0,2,1,1,0,0,1,0,0,0],"10.1001/archderm.136.12.1524"],[11352955,"Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol no. 30924.","J Clin Oncol",2001,"Sternberg et al.",2,[1,8],[12.16,10.26],14.63,10,8,7,[3,1,2,0,0,1,1,0,1,0,0,0,0,1,0,0],"10.1200/JCO.2001.19.10.2638"],[11566654,"Enteral compared with parenteral nutrition: a meta-analysis.","Am J Clin Nutr",2001,"Braunschweig et al.",0,[],[],14.63,10,8,7,[0,0,1,0,0,3,1,1,1,0,0,0,0,1,1,0],"10.1093/ajcn/74.4.534"],[11809181,"Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis.","Lancet",2002,"Huang et al.",0,[2,4],[6.77,5.78],14.63,8,8,7,[1,2,1,0,0,1,1,0,0,1,0,0,0,0,1,0],"10.1016/S0140-6736(02)07273-2"],[11903030,"Biochemical diagnosis of pheochromocytoma: which test is best?","JAMA",2002,"Lenders et al.",5,[1,7],[12.16,9.77],14.63,8,8,7,[1,0,0,2,0,1,1,1,0,1,0,0,0,0,0,1],"10.1001/jama.287.11.1427"],[12352035,"Glutamine supplementation in serious illness: a systematic review of the evidence.","Crit Care Med",2002,"Novak et al.",1,[2],[5.08],14.63,15,8,8,[2,0,1,1,0,0,2,1,1,2,0,0,0,0,0,0],"10.1097/00003246-200209000-00011"],[12453546,"Morphine for the relief of breathlessness in patients with chronic heart failure--a pilot study.","Eur J Heart Fail",2002,"Johnson et al.",2,[0,3],[9.77,2.69],14.63,10,8,7,[0,1,0,0,1,1,0,0,1,2,0,0,1,0,1,0],"10.1016/s1388-9842(02)00158-7"],[12453982,"A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes.","Diabetes Care",2002,"Castaneda et al.",2,[7],[14.63],14.63,10,8,7,[3,1,2,1,1,0,0,0,0,0,1,0,0,1,0,0],"10.2337/diacare.25.12.2335"],[12465151,"Specific antibody response after influenza immunization in systemic lupus erythematosus.","J Rheumatol",2002,"Abu-Shakra et al.",7,[11],[14.63],14.63,10,8,7,[2,0,0,1,2,1,0,1,0,1,0,0,1,0,0,0],""],[14593592,"Polymerase chain reaction for detection of herpes simplex virus (HSV) DNA on mucosal surfaces: comparison with HSV isolation in cell culture.","J Infect Dis",2003,"Wald et al.",7,[2,14],[14.63,1.0],14.63,8,8,7,[1,0,0,0,1,0,1,0,0,1,1,1,0,0,2,0],"10.1086/379043"],[14598247,"Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis.","Gastroenterology",2003,"Ullman et al.",5,[4,1],[14.63,5.29],14.63,11,8,9,[2,0,2,1,2,0,0,0,0,0,1,0,1,1,0,0],"10.1016/j.gastro.2003.08.023"],[14638353,"Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis.","Am J Gastroenterol",2003,"Harrison et al.",2,[4],[14.63],14.63,10,8,7,[0,2,1,0,0,0,0,1,1,0,2,1,0,0,1,0],"10.1111/j.1572-0241.2003.08699.x"],[14749454,"The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis.","N Engl J Med",2004,"Meunier et al.",2,[13,7],[14.63,12.65],14.63,10,8,7,[2,0,2,0,2,0,1,1,0,0,0,1,0,0,1,0],"10.1056/NEJMoa022436"],[15068979,"Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics.","Ann Intern Med",2004,"Numans et al.",0,[4],[14.63],14.63,8,8,7,[0,1,0,0,1,2,0,1,0,1,0,1,1,0,0,0],"10.7326/0003-4819-140-7-200404060-00011"],[15256390,"Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis?","Am J Respir Crit Care Med",2004,"Flaherty et al.",7,[3],[14.63],14.63,9,8,7,[1,0,1,0,0,0,0,2,0,0,2,1,1,0,1,0],"10.1164/rccm.200402-147OC"],[15269312,"Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome.","N Engl J Med",2004,"Brower et al.",2,[3],[12.16],14.63,12,8,7,[0,0,1,0,0,0,2,0,2,2,0,1,0,1,0,1],"10.1056/NEJMoa032193"],[15361495,"Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial.","Gut",2004,"Atkinson et al.",2,[4,12],[14.63,0.0],14.63,8,8,7,[2,0,0,0,1,1,0,1,0,0,1,1,1,0,0,0],"10.1136/gut.2003.037697"],[15448529,"Severe neurological complications after central neuraxial blockades in Sweden 1990-1999.","Anesthesiology",2004,"Moen et al.",5,[2,5],[1.0,0.0],14.63,8,8,7,[1,0,1,2,1,0,1,1,0,0,0,1,0,0,0,0],"10.1097/00000542-200410000-00021"],[15494579,"Comparison of MRI and CT for detection of acute intracerebral hemorrhage.","JAMA",2004,"Kidwell et al.",5,[0,5],[14.63,14.63],14.63,9,8,7,[0,1,2,0,0,0,0,0,2,0,0,1,1,1,0,1],"10.1001/jama.292.15.1823"],[15496623,"Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults.","N Engl J Med",2004,"Thwaites et al.",2,[2,5],[12.16,2.69],14.63,9,8,7,[1,0,1,0,0,2,1,0,1,1,0,0,0,0,0,1],"10.1056/NEJMoa040573"],[15872320,"Transcatheter thrombolytic therapy for acute mesenteric and portal vein thrombosis.","J Vasc Interv Radiol",2005,"Hollingshead et al.",5,[0],[14.63],14.63,9,8,7,[1,0,0,0,0,1,3,0,0,0,1,1,0,1,0,1],"10.1097/01.RVI.0000156265.79960.86"],[15880829,"Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual.","Arthritis Rheum",2005,"Fessler et al.",7,[11],[14.63],14.63,10,8,7,[0,2,0,1,1,0,0,2,1,0,1,0,0,2,0,0],"10.1002/art.21039"],[15893189,"Impact of pulmonary hypertension on the outcomes of noncardiac surgery: predictors of perioperative morbidity and mortality.","J Am Coll Cardiol",2005,"Ramakrishna et al.",7,[0,3],[9.77,2.69],14.63,13,8,7,[0,1,0,2,2,1,0,0,0,0,1,0,1,1,0,0],"10.1016/j.jacc.2005.02.055"],[16202532,"Suboccipital injection with a mixture of rapid- and long-acting steroids in cluster headache: a double-blind placebo-controlled study.","Pain",2005,"Ambrosini et al.",2,[5],[9.77],14.63,8,8,7,[1,2,1,1,0,1,0,0,0,0,0,0,1,0,0,1],"10.1016/j.pain.2005.07.015"],[16271333,"Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.","Clin Gastroenterol Hepatol",2005,"Qadeer et al.",0,[0,3],[9.02,6.2],14.63,9,8,8,[0,1,1,2,2,1,1,1,0,0,0,0,0,0,0,0],"10.1016/s1542-3565(05)00742-1"],[16291063,"Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomised controlled trial.","Lancet",2005,"Armstrong et al.",2,[0,7,14],[12.65,9.77,9.77],14.63,13,8,7,[0,2,1,0,0,3,2,0,0,1,0,0,0,1,1,0],"10.1016/S0140-6736(05)67695-7"],[16314620,"Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors.","J Clin Oncol",2005,"Bamias et al.",5,[13,16],[10.26,7.97],14.63,8,8,7,[2,1,0,1,1,0,0,0,1,0,0,1,1,0,0,0],"10.1200/JCO.2005.02.8670"],[16322083,"Safety and efficacy of influenza vaccination in systemic lupus erythematosus patients with quiescent disease.","Ann Rheum Dis",2006,"Holvast et al.",5,[11],[14.63],14.63,8,8,7,[2,0,0,1,1,1,0,0,1,0,1,0,0,0,0,1],"10.1136/ard.2005.043943"],[16401689,"Wireless capsule endoscopy versus ileocolonoscopy for the diagnosis of postoperative recurrence of Crohn's disease: a prospective study.","Gut",2006,"Bourreille et al.",5,[4],[14.63],14.63,8,8,7,[0,0,1,0,1,0,1,0,1,0,1,0,0,1,2,0],"10.1136/gut.2005.081851"],[16446331,"Randomized double-blind trial of estrogen replacement therapy versus placebo in stage I or II endometrial cancer: a Gynecologic Oncology Group Study.","J Clin Oncol",2006,"Barakat et al.",2,[1,9],[13.81,8.47],14.63,9,8,7,[0,0,0,1,1,0,2,1,0,0,0,1,0,1,0,2],"10.1200/JCO.2005.02.8464"],[16563926,"Prognostic value of routine preoperative electrocardiography in patients undergoing noncardiac surgery.","Am J Cardiol",2006,"Noordzij et al.",5,[0],[8.37],14.63,12,8,7,[1,0,0,2,2,0,1,0,0,0,0,0,1,1,0,1],"10.1016/j.amjcard.2005.10.058"],[16762617,"Predictive and protective factors associated with colorectal cancer in ulcerative colitis: A case-control study.","Gastroenterology",2006,"Velayos et al.",5,[4,1],[14.63,6.84],14.63,10,8,8,[1,0,2,0,2,0,0,1,0,0,2,0,1,1,0,0],"10.1053/j.gastro.2006.03.028"],[16794385,"A comparison of hand-sewn versus stapled ileal pouch anal anastomosis (IPAA) following proctocolectomy: a meta-analysis of 4183 patients.","Ann Surg",2006,"Lovegrove et al.",0,[4],[14.63],14.63,9,8,8,[1,0,0,0,1,0,2,2,0,0,0,0,1,1,1,0],"10.1097/01.sla.0000225031.15405.a3"],[16799943,"Pregnancy outcome after liver transplantation: a single-center experience of 71 pregnancies in 45 recipients.","Liver Transpl",2006,"Christopher et al.",7,[9],[6.77],14.63,8,8,7,[1,0,0,0,2,1,0,0,0,0,1,0,1,1,1,0],"10.1002/lt.20810"],[16827858,"Cyclosporin versus tacrolimus as primary immunosuppressant after liver transplantation: a meta-analysis.","Am J Transplant",2006,"McAlister et al.",0,[4],[10.83],14.63,8,8,7,[0,0,0,0,0,1,1,0,0,1,1,0,0,2,1,1],"10.1111/j.1600-6143.2006.01360.x"],[17032194,"Outcome of surgical versus percutaneous drainage of abdominal and pelvic abscesses in Crohn's disease.","Am J Gastroenterol",2006,"Gutierrez et al.",5,[2,4],[2.0,12.65],14.63,9,8,7,[0,0,1,1,1,0,1,2,0,2,0,0,0,0,1,0],"10.1111/j.1572-0241.2006.00757.x"],[17114188,"Infliximab maintains a high degree of clinical response in patients with active psoriatic arthritis through 1 year of treatment: results from the IMPACT 2 trial.","Ann Rheum Dis",2007,"Kavanaugh et al.",2,[14,11,13],[12.65,10.26,10.26],14.63,9,8,7,[2,2,1,0,1,0,0,1,1,0,1,0,0,0,0,0],"10.1136/ard.2006.058339"],[17170120,"Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.","Blood",2007,"Moorman et al.",3,[1,10],[14.63,12.16],14.63,8,8,7,[0,1,1,0,0,1,1,0,0,0,0,0,2,1,1,0],"10.1182/blood-2006-10-051912"],[17329305,"Adalimumab alone and in combination with disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis in clinical practice: the Research in Active Rheumatoid Arthritis (ReAct) trial.","Ann Rheum Dis",2007,"Burmester et al.",3,[11],[14.63],14.63,8,8,7,[1,0,0,2,1,1,1,0,0,0,0,0,0,1,1,0],"10.1136/ard.2006.066761"],[17471546,"Churg-Strauss syndrome with poor-prognosis factors: A prospective multicenter trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in forty-eight patients.","Arthritis Rheum",2007,"Cohen et al.",2,[0,11,14],[14.63,14.63,13.27],14.63,8,8,7,[1,0,0,0,1,1,0,0,0,1,0,0,2,1,1,0],"10.1002/art.22679"],[17576737,"Safety and efficacy of hepatitis B vaccine in systemic lupus erythematosus.","Lupus",2007,"Kuruma et al.",3,[11],[14.63],14.63,9,8,7,[2,0,0,1,1,2,0,0,1,0,0,0,0,1,0,1],"10.1177/0961203307078225"],[17588407,"Risk factors for occult mediastinal metastases in clinical stage I non-small cell lung cancer.","Ann Thorac Surg",2007,"Lee et al.",5,[1,3],[14.63,14.63],14.63,9,8,7,[0,1,0,2,0,1,0,1,1,0,0,0,0,0,1,1],"10.1016/j.athoracsur.2007.03.081"],[17920916,"Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial.","Lancet",2007,"Facon et al.",2,[1,0,10],[14.63,12.16,12.16],14.63,9,8,7,[2,1,1,2,1,0,0,0,1,0,1,0,0,0,0,0],"10.1016/S0140-6736(07)61537-2"],[18162494,"Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial.","Diabetes Care",2008,"Blume et al.",2,[14,0,7],[12.16,9.77,9.77],14.63,9,8,7,[0,1,1,1,0,3,1,0,0,1,0,0,0,0,0,1],"10.2337/dc07-2196"],[18185903,"The role of preoperative urodynamic testing in stress-continent women undergoing sacrocolpopexy: the Colpopexy and Urinary Reduction Efforts (CARE) randomized surgical trial.","Int Urogynecol J Pelvic Floor Dysfunct",2008,"Visco et al.",2,[8,9],[7.47,4.65],14.63,10,8,7,[0,1,0,1,1,1,3,0,0,0,1,0,1,0,0,0],"10.1007/s00192-007-0498-2"],[18242357,"A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.","Urology",2008,"Peterson et al.",2,[8,2],[12.16,14.63],14.63,8,8,7,[1,0,0,0,1,0,1,0,0,0,1,1,0,1,0,2],"10.1016/j.urology.2007.09.002"],[18318689,"Prospective multicenter evaluation of the pulmonary embolism rule-out criteria.","J Thromb Haemost",2008,"Kline et al.",5,[0,3],[14.63,9.02],14.63,9,8,7,[1,0,0,0,1,0,0,1,0,1,2,1,0,0,0,1],"10.1111/j.1538-7836.2008.02944.x"],[18378417,"CA 125, PET alone, PET-CT, CT and MRI in diagnosing recurrent ovarian carcinoma: a systematic review and meta-analysis.","Eur J Radiol",2009,"Gu et al.",0,[1,7,9],[14.63,14.63,14.63],14.63,8,8,7,[1,1,0,0,0,0,0,1,2,0,1,0,1,1,0,0],"10.1016/j.ejrad.2008.02.019"],[18413638,"Ten-year follow-up of radiation therapy oncology group protocol 92-02: a phase III trial of the duration of elective androgen deprivation in locally advanced prostate cancer.","J Clin Oncol",2008,"Horwitz et al.",2,[1,8,9],[14.63,14.63,14.63],14.63,11,8,7,[1,2,2,2,0,0,2,1,0,0,0,1,0,0,0,0],"10.1200/JCO.2007.14.9021"],[18440124,"Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients.","Eur Urol",2008,"Leijte et al.",5,[1,8,9],[12.16,12.16,12.16],14.63,10,8,7,[0,0,4,0,1,0,0,0,0,1,0,1,1,1,1,0],"10.1016/j.eururo.2008.04.016"],[18453857,"Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006.","AIDS",2008,"Townsend et al.",7,[2,9,12],[14.63,14.63,14.63],14.63,10,8,7,[1,1,1,4,0,0,0,1,1,0,0,0,0,1,0,0],"10.1097/QAD.0b013e3282f9b67a"],[18477350,"Prospective evaluation of advanced molecular markers and imaging techniques in patients with indeterminate bile duct strictures.","Am J Gastroenterol",2008,"Levy et al.",5,[4],[14.63],14.63,8,8,7,[0,1,1,2,1,0,1,1,0,0,0,0,0,0,0,1],"10.1111/j.1572-0241.2007.01776.x"],[18536964,"Infliximab in ulcerative colitis is associated with an increased risk of postoperative complications after restorative proctocolectomy.","Dis Colon Rectum",2008,"Mor et al.",5,[4],[14.63],14.63,9,8,7,[3,0,0,1,1,0,1,1,0,0,0,0,1,1,0,0],"10.1007/s10350-008-9364-7"],[18556626,"Brain-type natriuretic peptide levels in the prediction of adverse outcome in patients with pulmonary embolism: a systematic review and meta-analysis.","Am J Respir Crit Care Med",2008,"Klok et al.",0,[0,3],[14.63,12.65],14.63,9,8,7,[2,0,2,1,0,0,0,1,1,1,1,0,0,0,0,0],"10.1164/rccm.200803-459OC"],[18624836,"A clinical study comparing methyl aminolevulinate photodynamic therapy and surgery in small superficial basal cell carcinoma (8-20 mm), with a 12-month follow-up.","J Eur Acad Dermatol Venereol",2008,"Szeimies et al.",2,[1,14],[14.63,14.63],14.63,9,8,7,[0,0,0,1,2,1,0,1,1,1,0,0,2,0,0,0],"10.1111/j.1468-3083.2008.02803.x"],[18625886,"Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group.","Blood",2008,"Geisler et al.",3,[1,10],[14.63,14.63],14.63,8,8,7,[1,1,0,2,0,0,0,1,0,0,0,1,0,1,0,1],"10.1182/blood-2008-03-147025"],[18626628,"Immunonutrition in critically ill patients: a systematic review and analysis of the literature.","Intensive Care Med",2008,"Marik et al.",0,[2],[7.47],14.63,13,8,7,[2,0,1,1,0,1,1,0,0,1,0,0,0,0,0,1],"10.1007/s00134-008-1213-6"],[18673426,"Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B.","J Viral Hepat",2009,"Chan et al.",5,[4,2],[14.63,2.69],14.63,8,8,7,[0,1,1,1,1,0,1,0,0,0,1,0,0,2,0,0],"10.1111/j.1365-2893.2008.01037.x"],[18753639,"Telmisartan to prevent recurrent stroke and cardiovascular events.","N Engl J Med",2008,"Yusuf et al.",2,[0,5],[14.63,6.77],14.63,12,8,7,[1,1,1,0,0,1,0,1,0,0,0,0,0,2,1,0],"10.1056/NEJMoa0804593"],[18986640,"Amniocentesis and mother-to-child human immunodeficiency virus transmission in the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales French Perinatal Cohort.","Am J Obstet Gynecol",2009,"Mandelbrot et al.",5,[9,2,12],[12.16,5.78,5.78],14.63,9,8,7,[1,1,0,2,0,2,0,0,1,0,1,1,0,0,0,0],"10.1016/j.ajog.2008.08.049"],[18989542,"Prospective validation of the Pulmonary Embolism Severity Index. A clinical prognostic model for pulmonary embolism.","Thromb Haemost",2008,"Donzé et al.",5,[0,3],[14.63,10.26],14.63,9,8,7,[3,0,0,1,0,0,0,1,1,1,0,0,0,1,1,0],"10.1160/th08-05-0285"],[19017587,"Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis infection: a randomized trial.","Ann Intern Med",2008,"Menzies et al.",2,[2],[14.63],14.63,8,8,7,[0,1,0,0,0,1,2,1,0,1,0,0,1,0,1,0],"10.7326/0003-4819-149-10-200811180-00003"],[19092091,"Nephrotoxicity of iso-osmolar iodixanol compared with nonionic low-osmolar contrast media: meta-analysis of randomized controlled trials.","Radiology",2009,"Heinrich et al.",0,[8],[9.02],14.63,14,8,8,[2,2,3,1,0,0,1,0,1,1,0,0,0,0,0,0],"10.1148/radiol.2501080833"],[19151274,"Elimination of preoperative testing in ambulatory surgery.","Anesth Analg",2009,"Chung et al.",2,[0],[5.08],14.63,10,8,7,[2,0,1,1,2,0,1,0,1,0,0,0,1,0,0,0],"10.1213/ane.0b013e318176bc19"],[19188680,"Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil.","J Clin Oncol",2009,"Reck et al.",2,[1,3],[14.63,12.65],14.63,10,8,7,[2,3,1,1,0,0,0,1,0,1,0,0,1,0,0,0],"10.1200/JCO.2007.14.5466"],[19251380,"Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: four-year results of a prospective phase II study.","Int J Radiat Oncol Biol Phys",2009,"Fakiris et al.",3,[1,3],[14.63,14.63],14.63,8,8,7,[0,1,1,2,0,0,1,0,0,0,0,1,0,1,0,1],"10.1016/j.ijrobp.2008.11.042"],[19375519,"Mesalamine once daily is more effective than twice daily in patients with quiescent ulcerative colitis.","Clin Gastroenterol Hepatol",2009,"Dignass et al.",2,[4],[14.63],14.63,9,8,7,[2,1,1,0,2,0,1,0,0,0,0,0,1,1,0,0],"10.1016/j.cgh.2009.04.004"],[19403881,"From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid tumors.","J Nucl Med",2009,"Wahl et al.",6,[1],[14.63],14.63,10,10,6,[0,0,1,0,1,2,0,1,0,0,2,0,1,2,0,0],"10.2967/jnumed.108.057307"],[19506160,"Primary therapy of Waldenström macroglobulinemia with bortezomib, dexamethasone, and rituximab: WMCTG clinical trial 05-180.","J Clin Oncol",2009,"Treon et al.",3,[0,1,10],[14.63,14.63,14.63],14.63,10,8,7,[0,1,3,1,0,0,1,1,0,0,0,2,0,1,0,0],"10.1200/JCO.2008.20.4677"],[19520759,"Quantitation of serum monoclonal proteins: relationship between agarose gel electrophoresis and immunonephelometry.","Clin Chem",2009,"Murray et al.",7,[10,0],[14.63,10.26],14.63,8,8,7,[0,1,1,1,0,0,0,1,0,1,0,2,0,0,0,1],"10.1373/clinchem.2009.124461"],[19546417,"The frequency of hyperkalemia and its significance in chronic kidney disease.","Arch Intern Med",2009,"Einhorn et al.",5,[7,8],[4.65,4.65],14.63,8,8,7,[0,0,1,0,1,0,0,1,0,0,0,1,0,2,1,1],"10.1001/archinternmed.2009.132"],[19601965,"Very high prevalence of thyroid nodules detected by high frequency (13 MHz) ultrasound examination.","Eur J Clin Invest",2009,"Guth et al.",5,[1,7],[14.63,14.63],14.63,8,8,7,[0,0,1,0,0,2,0,1,0,0,0,1,1,0,1,1],"10.1111/j.1365-2362.2009.02162.x"],[19620517,"Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial.","Hypertension",2009,"Pimenta et al.",2,[0],[14.63],14.63,10,8,7,[0,0,1,0,0,1,0,2,1,1,0,0,0,0,1,1],"10.1161/HYPERTENSIONAHA.109.131235"],[19761634,"Epidemiology of pregnancy-associated venous thromboembolism: a population-based study in Canada.","J Obstet Gynaecol Can",2009,"Liu et al.",5,[0,9,10],[9.77,9.77,6.77],14.63,9,8,7,[1,0,0,1,0,0,0,2,0,0,0,1,1,1,0,1],"10.1016/S1701-2163(16)34240-2"],[19821343,"Preoperative fasting for preventing perioperative complications in children.","Cochrane Database Syst Rev",2009,"Brady et al.",0,[3,4,2],[1.0,3.1,1.0],14.63,9,8,7,[1,2,1,2,0,0,1,1,0,0,1,0,0,0,0,0],"10.1002/14651858.CD005285.pub2"],[19825505,"The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study.","Eur Urol",2010,"Roehrborn et al.",2,[8,9],[14.63,14.63],14.63,8,8,7,[1,1,1,0,0,1,2,0,0,0,0,0,1,0,1,0],"10.1016/j.eururo.2009.09.035"],[19826273,"Efficacy of endoscopic ultrasound-guided celiac plexus block and celiac plexus neurolysis for managing abdominal pain associated with chronic pancreatitis and pancreatic cancer.","J Clin Gastroenterol",2010,"Kaufman et al.",0,[4,1,7],[14.63,2.0,1.0],14.63,8,8,7,[0,1,1,0,1,2,0,1,1,0,0,1,0,0,0,0],"10.1097/MCG.0b013e3181bb854d"],[19850703,"Three-year efficacy of complex insulin regimens in type 2 diabetes.","N Engl J Med",2009,"Holman et al.",2,[7],[14.63],14.63,10,8,9,[1,1,2,0,1,0,1,0,1,0,0,1,0,0,0,0],"10.1056/NEJMoa0905479"],[19874470,"Clinical course of high-risk patients diagnosed with antiphospholipid syndrome.","J Thromb Haemost",2010,"Pengo et al.",5,[0,11,9],[0.0,14.63,0.0],14.63,8,8,7,[0,1,1,0,0,0,0,1,1,1,1,0,0,0,2,0],"10.1111/j.1538-7836.2009.03674.x"],[19926696,"Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFractureScores.","BMJ",2009,"Hippisley-Cox et al.",5,[13,7],[14.63,9.48],14.63,10,8,7,[0,0,1,0,0,0,2,0,1,1,0,1,0,2,2,0],"10.1136/bmj.b4229"],[19935783,"Esophageal dilation in eosinophilic esophagitis: effectiveness, safety, and impact on the underlying inflammation.","Am J Gastroenterol",2010,"Schoepfer et al.",5,[4,10],[14.63,12.16],14.63,9,8,7,[0,0,1,1,0,0,0,1,0,1,0,0,0,2,1,1],"10.1038/ajg.2009.657"],[19945740,"The potential benefit of 6 vs. 3 cycles of chemotherapy in subsets of women with early-stage high-risk epithelial ovarian cancer: an exploratory analysis of a Gynecologic Oncology Group study.","Gynecol Oncol",2010,"Chan et al.",2,[1,7,9],[14.63,14.63,14.63],14.63,9,8,7,[0,0,1,0,0,0,1,1,2,0,1,0,1,2,0,0],"10.1016/j.ygyno.2009.10.073"],[19949013,"Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon.","J Clin Oncol",2010,"West et al.",7,[1,4],[14.63,14.63],14.63,10,8,7,[1,1,1,0,1,0,2,0,0,0,0,1,0,0,2,0],"10.1200/JCO.2009.24.1448"],[20089951,"Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.","N Engl J Med",2010,"Celum et al.",2,[2,9,12],[14.63,12.16,4.65],14.63,8,8,7,[0,1,1,0,1,1,1,0,0,0,1,0,0,0,2,0],"10.1056/NEJMoa0904849"],[20170770,"OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009.","Osteoarthritis Cartilage",2010,"Zhang et al.",0,[11],[10.26],14.63,9,8,7,[1,0,1,2,1,1,1,0,1,0,0,0,0,0,0,0],"10.1016/j.joca.2010.01.013"],[20179283,"Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.","JAMA",2010,"Jones et al.",2,[2],[11.38],14.63,14,8,8,[0,1,1,2,0,1,1,0,0,3,0,0,0,1,0,0],"10.1001/jama.2010.158"],[20301163,"Endoscopic resection of early gastric cancer treated by guideline and expanded National Cancer Centre criteria.","Br J Surg",2010,"Gotoda et al.",7,[1,4],[14.63,14.63],14.63,10,8,7,[1,0,1,2,1,0,0,0,0,0,0,1,1,0,0,2],"10.1002/bjs.7033"],[20347733,"Are endoscopic therapies appropriate for superficial submucosal esophageal adenocarcinoma? An analysis of esophagectomy specimens.","J Am Coll Surg",2010,"Sepesi et al.",5,[1,4],[14.63,14.63],14.63,8,8,7,[0,1,1,1,2,1,0,0,1,1,0,0,0,0,0,0],"10.1016/j.jamcollsurg.2010.01.003"],[20351774,"Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials.","PLoS Med",2010,"Mozaffarian et al.",0,[0],[7.97],14.63,9,8,7,[1,0,1,0,1,1,0,1,2,0,1,0,0,0,0,0],"10.1371/journal.pmed.1000252"],[20360136,"Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study.","Ann Rheum Dis",2010,"Tanaka et al.",7,[11],[14.63],14.63,9,8,7,[0,1,0,3,1,0,1,1,0,1,0,0,0,1,0,0],"10.1136/ard.2009.121491"],[20383209,"Risk of hepatitis B surface antigen seroreversion after allogeneic hematopoietic SCT.","Bone Marrow Transplant",2011,"Viganò et al.",7,[2,4,1],[14.63,9.77,1.55],14.63,10,8,7,[0,2,1,1,0,2,0,0,1,0,0,0,0,1,2,0],"10.1038/bmt.2010.70"],[20431041,"Randomized clinical trial of long-acting somatostatin for autosomal dominant polycystic kidney and liver disease.","J Am Soc Nephrol",2010,"Hogan et al.",2,[4,8,17],[9.02,5.29,5.29],14.63,9,8,7,[0,0,0,1,2,0,0,0,1,0,0,2,0,1,1,1],"10.1681/ASN.2009121291"],[20434198,"Cytoreductive surgery for advanced or recurrent endometrial cancer: a meta-analysis.","Gynecol Oncol",2010,"Barlin et al.",0,[1,9],[14.63,14.63],14.63,9,8,7,[0,0,0,1,0,0,2,0,0,1,1,1,1,0,0,1],"10.1016/j.ygyno.2010.04.005"],[20452521,"Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.","Lancet",2010,"Sarwar et al.",7,[0],[9.77],14.63,14,8,9,[2,0,0,0,1,1,0,0,2,0,0,1,0,1,0,1],"10.1016/S0140-6736(10)60545-4"],[20482819,"Meta-analysis of the diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of coronary artery disease.","J Cardiovasc Magn Reson",2010,"Hamon et al.",0,[0],[14.63],14.63,14,10,7,[0,1,1,4,0,0,1,0,0,0,1,2,0,1,0,0],"10.1186/1532-429X-12-29"],[20600018,"Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers.","Gastroenterology",2010,"Heald et al.",7,[1,4,17],[13.27,10.26,6.77],14.63,8,8,7,[0,0,0,1,2,0,1,0,1,1,0,1,0,1,0,0],"10.1053/j.gastro.2010.06.061"],[20634346,"Faecal calprotectin for screening of patients with suspected inflammatory bowel disease: diagnostic meta-analysis.","BMJ",2010,"van Rheenen et al.",0,[4],[14.63],14.63,9,8,7,[0,0,0,1,1,1,0,1,0,0,1,0,2,2,0,0],"10.1136/bmj.c3369"],[20723799,"Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial.","J Am Coll Cardiol",2010,"O'Connor et al.",2,[0],[7.97],14.63,13,8,7,[0,3,1,0,0,1,0,0,1,1,0,0,1,0,0,1],"10.1016/j.jacc.2010.03.068"],[20921437,"Complication rates associated with pacemaker or implantable cardioverter-defibrillator generator replacements and upgrade procedures: results from the REPLACE registry.","Circulation",2010,"Poole et al.",5,[0],[11.65],14.63,14,10,6,[0,3,1,1,1,0,0,0,0,0,0,0,1,0,2,1],"10.1161/CIRCULATIONAHA.110.976076"],[20946997,"Coronary risk stratification, discrimination, and reclassification improvement based on quantification of subclinical coronary atherosclerosis: the Heinz Nixdorf Recall study.","J Am Coll Cardiol",2010,"Erbel et al.",5,[0,7],[12.65,6.2],14.63,10,8,8,[0,1,0,0,1,0,2,1,1,1,2,0,0,0,0,0],"10.1016/j.jacc.2010.06.030"],[20960392,"Risk of lymph node metastasis associated with deeper invasion by early adenocarcinoma of the esophagus and cardia: study based on endoscopic resection specimens.","Endoscopy",2010,"Alvarez Herrero et al.",5,[1,4],[12.16,14.63],14.63,9,8,7,[0,0,0,1,2,0,0,0,1,1,0,1,1,1,0,0],"10.1055/s-0030-1255858"],[20966436,"A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients.","Anesth Analg",2011,"Hamilton et al.",0,[0],[5.78],14.63,10,8,7,[0,1,1,1,1,0,2,1,0,0,0,0,1,0,0,0],"10.1213/ANE.0b013e3181eeaae5"],[21069663,"Magnesium sulphate and other anticonvulsants for women with pre-eclampsia.","Cochrane Database Syst Rev",2010,"Duley et al.",0,[9],[14.63],14.63,9,8,8,[0,0,0,0,0,2,1,1,0,1,1,0,1,0,0,1],"10.1002/14651858.CD000025.pub2"],[21178867,"Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: a systematic review.","Dis Colon Rectum",2010,"Hwang et al.",1,[4],[14.63],14.63,8,8,7,[0,1,1,2,1,0,0,0,0,1,1,0,0,1,0,0],"10.1007/DCR.0b013e3181f5643c"],[21193451,"Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery.","Gut",2011,"Parry et al.",7,[1,4,7],[14.63,12.16,7.97],14.63,11,8,10,[0,0,2,1,1,0,1,0,0,0,1,1,1,0,0,0],"10.1136/gut.2010.228056"],[21205966,"Gait speed and survival in older adults.","JAMA",2011,"Studenski et al.",5,[1],[6.77],14.63,9,8,7,[0,2,1,0,0,0,0,0,0,1,1,1,2,1,0,0],"10.1001/jama.2010.1923"],[21208974,"Evaluation of the efficacy and safety of RLY5016, a polymeric potassium binder, in a double-blind, placebo-controlled study in patients with chronic heart failure (the PEARL-HF) trial.","Eur Heart J",2011,"Pitt et al.",2,[0,7],[9.77,4.65],14.63,10,8,7,[0,1,1,0,0,1,0,1,1,0,0,0,0,2,1,0],"10.1093/eurheartj/ehq502"],[21233157,"Use of weaning protocols for reducing duration of mechanical ventilation in critically ill adult patients: Cochrane systematic review and meta-analysis.","BMJ",2011,"Blackwood et al.",0,[3],[9.02],14.63,8,8,7,[0,0,1,1,0,1,1,0,0,2,1,0,0,1,0,0],"10.1136/bmj.c7237"],[21245435,"Pralatrexate in patients with relapsed or refractory peripheral T-cell lymphoma: results from the pivotal PROPEL study.","J Clin Oncol",2011,"O'Connor et al.",3,[1,10],[14.63,14.63],14.63,9,8,7,[0,0,1,0,1,1,0,1,1,0,0,2,0,0,2,0],"10.1200/JCO.2010.29.9024"],[21248168,"Pathophysiological mechanisms of atrial fibrillation: a translational appraisal.","Physiol Rev",2011,"Schotten et al.",6,[0],[14.63],14.63,15,8,7,[0,1,0,1,0,2,2,2,0,0,0,1,0,1,0,0],"10.1152/physrev.00031.2009"],[21289598,"Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts.","Kidney Int",2011,"Astor et al.",0,[8],[14.63],14.63,8,8,7,[0,1,1,1,0,0,0,0,2,0,0,0,1,1,0,1],"10.1038/ki.2010.550"],[21440672,"Oral bisacodyl is effective and well-tolerated in patients with chronic constipation.","Clin Gastroenterol Hepatol",2011,"Kamm et al.",2,[4,5],[11.38,4.65],14.63,10,8,8,[0,0,0,0,0,1,1,1,1,0,1,0,1,0,2,0],"10.1016/j.cgh.2011.03.026"],[21482992,"American Society of Clinical Oncology provisional clinical opinion: epidermal growth factor receptor (EGFR) Mutation testing for patients with advanced non-small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy.","J Clin Oncol",2011,"Keedy et al.",7,[1,3],[12.16,12.16],14.63,12,8,9,[1,2,2,0,2,0,1,0,1,0,0,1,0,0,0,0],"10.1200/JCO.2010.31.8923"],[21641282,"Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis.","Lancet Neurol",2011,"Vlak et al.",0,[0,5],[7.47,2.0],14.63,8,8,7,[0,0,0,1,2,1,0,1,1,0,0,0,0,1,1,0],"10.1016/S1474-4422(11)70109-0"],[21645977,"Stereotactic body radiotherapy for primary hepatocellular carcinoma.","Int J Radiat Oncol Biol Phys",2011,"Andolino et al.",7,[1,4],[14.63,13.81],14.63,14,8,9,[0,0,0,0,1,2,1,0,1,0,2,4,0,0,1,0],"10.1016/j.ijrobp.2011.04.011"],[21803753,"A systematic literature review of drug therapies for the treatment of psoriatic arthritis: current evidence and meta-analysis informing the EULAR recommendations for the management of psoriatic arthritis.","Ann Rheum Dis",2012,"Ash et al.",0,[11,13,14],[12.16,12.16,12.65],14.63,8,8,7,[0,1,1,2,1,1,0,1,0,0,1,0,0,0,0,0],"10.1136/ard.2011.150995"],[21821305,"Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer.","Radiother Oncol",2011,"Pötter et al.",7,[1,9],[14.63,14.63],14.63,8,8,7,[0,0,0,1,0,1,1,0,0,1,0,1,0,0,1,2],"10.1016/j.radonc.2011.07.012"],[21835400,"Capsule endoscopy in nonresponsive celiac disease.","Gastrointest Endosc",2011,"Atlas et al.",5,[4,7],[14.63,9.02],14.63,8,8,7,[0,0,1,1,2,0,1,0,0,0,1,1,1,0,0,0],"10.1016/j.gie.2011.05.049"],[21898479,"Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients.","Hepatology",2012,"Myers et al.",3,[4,7],[14.63,0.0],14.63,8,8,7,[0,1,1,1,2,0,1,0,0,0,1,1,0,0,0,0],"10.1002/hep.24624"],[21995387,"Breast-cancer adjuvant therapy with zoledronic acid.","N Engl J Med",2011,"Coleman et al.",2,[1],[14.63],14.63,10,8,7,[0,2,1,1,1,1,3,0,0,0,0,0,0,1,0,0],"10.1056/NEJMoa1105195"],[22045767,"Spectrum of cancer risk among US solid organ transplant recipients.","JAMA",2011,"Engels et al.",5,[1],[3.74],14.63,8,8,7,[0,0,0,0,0,1,0,0,1,0,2,0,1,1,1,1],"10.1001/jama.2011.1592"],[22127957,"Baseline radiographic damage, elevated acute-phase reactant levels, and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis.","Arthritis Rheum",2012,"Poddubnyy et al.",5,[11,13],[14.63,14.63],14.63,11,8,7,[0,0,0,1,1,0,1,2,2,0,1,0,1,0,0,0],"10.1002/art.33465"],[22130426,"A new classification scheme for treating blunt aortic injury.","J Vasc Surg",2012,"Starnes et al.",5,[13,0],[4.04,12.65],14.63,11,8,7,[0,0,0,0,1,0,1,0,0,0,0,1,2,1,1,3],"10.1016/j.jvs.2011.07.073"],[22150035,"Three months of rifapentine and isoniazid for latent tuberculosis infection.","N Engl J Med",2011,"Sterling et al.",2,[2],[14.63],14.63,8,8,7,[0,0,1,0,1,1,1,0,0,2,1,0,1,0,0,0],"10.1056/NEJMoa1104875"],[22253460,"Meta-analysis of psychosocial interventions to reduce pain in patients with cancer.","J Clin Oncol",2012,"Sheinfeld Gorin et al.",0,[1],[14.63],14.63,10,8,7,[0,0,2,1,0,1,0,2,2,0,1,0,0,0,1,0],"10.1200/JCO.2011.37.0437"],[22307571,"Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.","JAMA",2012,"Rice et al.",2,[3],[0.0],14.63,11,8,8,[0,0,1,1,0,2,2,0,1,1,2,0,0,0,0,0],"10.1001/jama.2012.137"],[22345712,"Oral nutritional interventions in malnourished patients with cancer: a systematic review and meta-analysis.","J Natl Cancer Inst",2012,"Baldwin et al.",0,[1,7],[11.38,5.78],14.63,9,8,7,[0,0,0,1,0,1,1,0,1,1,3,0,0,0,0,1],"10.1093/jnci/djr556"],[22475493,"Cervical pessary in pregnant women with a short cervix (PECEP): an open-label randomised controlled trial.","Lancet",2012,"Goya et al.",2,[9],[13.81],14.63,9,8,7,[0,0,2,1,0,0,2,0,1,1,0,0,0,1,0,1],"10.1016/S0140-6736(12)60030-0"],[22627883,"Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.","Thromb Haemost",2012,"Marlu et al.",2,[0,5],[12.16,6.77],14.63,11,8,8,[0,1,3,1,1,0,0,1,0,1,0,0,1,0,0,0],"10.1160/TH12-03-0179"],[22661458,"The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK.","Gut",2013,"Gavin et al.",7,[4,1],[14.63,12.16],14.63,11,8,7,[0,0,1,0,0,3,1,1,0,1,1,1,0,0,0,0],"10.1136/gutjnl-2011-301848"],[22895933,"Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes.","Cochrane Database Syst Rev",2012,"Rabe et al.",0,[9],[2.69],14.63,8,8,7,[0,0,1,0,2,0,1,1,0,1,1,0,0,1,0,0],"10.1002/14651858.CD003248.pub3"],[23108725,"Fetal fraction in maternal plasma cell-free DNA at 11-13 weeks' gestation: relation to maternal and fetal characteristics.","Ultrasound Obstet Gynecol",2013,"Ashoor et al.",7,[17,9],[11.38,7.97],14.63,9,8,7,[0,0,0,0,1,1,1,0,1,1,2,0,0,1,0,0],"10.1002/uog.12331"],[23150698,"Routine bone marrow biopsy has little or no therapeutic consequence for positron emission tomography/computed tomography-staged treatment-naive patients with Hodgkin lymphoma.","J Clin Oncol",2012,"El-Galaly et al.",5,[1,10],[14.63,14.63],14.63,11,8,8,[0,0,0,3,2,1,2,1,0,0,0,1,0,1,0,0],"10.1200/JCO.2012.42.4036"],[23319686,"Effects of psycho-oncologic interventions on emotional distress and quality of life in adult patients with cancer: systematic review and meta-analysis.","J Clin Oncol",2013,"Faller et al.",0,[1],[14.63],14.63,8,8,7,[0,0,0,2,1,0,1,0,1,0,1,0,1,0,1,0],"10.1200/JCO.2011.40.8922"],[23419382,"Antibody response to infliximab and its impact on pharmacokinetics can be transient.","Am J Gastroenterol",2013,"Vande Casteele et al.",5,[4],[14.63],14.63,8,8,7,[0,0,0,1,1,1,1,1,0,0,0,0,0,1,2,0],"10.1038/ajg.2013.12"],[23440794,"Screening for prostate cancer.","Cochrane Database Syst Rev",2013,"Ilic et al.",0,[1,8,9],[12.16,12.16,12.16],14.63,8,8,7,[0,0,1,0,0,1,0,1,1,1,1,2,0,0,0,0],"10.1002/14651858.CD004720.pub3"],[23443444,"Surveillance intervals for small abdominal aortic aneurysms: a meta-analysis.","JAMA",2013,"Bown et al.",0,[0],[14.63],14.63,10,8,7,[0,0,0,1,0,1,0,1,1,0,0,1,2,2,0,0],"10.1001/jama.2013.950"],[23612857,"Prophylactic pancreatic stent placement and post-ERCP pancreatitis: an updated meta-analysis.","J Gastroenterol",2014,"Mazaki et al.",0,[4],[14.63],14.63,8,8,7,[0,0,0,1,1,0,2,0,0,0,1,0,0,1,1,1],"10.1007/s00535-013-0806-1"],[23728654,"Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema.","Cochrane Database Syst Rev",2013,"Vital et al.",0,[0,3],[5.78,4.04],14.63,11,8,7,[0,0,0,0,1,1,1,1,0,2,0,0,0,1,1,0],"10.1002/14651858.CD005351.pub3"],[23733765,"Impact of age on the efficacy of newer adjuvant therapies in patients with stage II/III colon cancer: findings from the ACCENT database.","J Clin Oncol",2013,"McCleary et al.",7,[1,4],[14.63,12.16],14.63,10,8,7,[0,1,2,0,0,0,1,2,0,1,1,0,0,1,0,0],"10.1200/JCO.2013.49.6638"],[23857305,"Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study.","Hepatology",2014,"Geenes et al.",5,[9,4],[12.16,10.83],14.63,9,8,7,[0,0,0,0,0,1,0,0,0,1,1,1,2,1,0,1],"10.1002/hep.26617"],[23867200,"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration.","Lancet Neurol",2013,"Wardlaw et al.",7,[5,0],[12.16,11.38],14.63,9,8,7,[0,1,0,1,1,0,0,2,0,2,0,0,1,1,0,0],"10.1016/S1474-4422(13)70124-8"],[24002127,"Efficacy of Helicobacter pylori eradication therapy on functional dyspepsia: a meta-analysis of randomized controlled studies with 12-month follow-up.","J Clin Gastroenterol",2014,"Zhao et al.",0,[2],[14.63],14.63,9,8,8,[0,0,0,0,1,0,2,0,0,0,1,1,0,1,1,1],"10.1097/MCG.0b013e31829f2e25"],[24141369,"Impact of allele-level HLA matching on outcomes after myeloablative single unit umbilical cord blood transplantation for hematologic malignancy.","Blood",2014,"Eapen et al.",7,[1,10],[14.63,14.63],14.63,9,8,7,[0,0,0,0,0,1,0,0,1,1,3,0,0,1,1,1],"10.1182/blood-2013-05-506253"],[24190112,"Randomized, open-label, phase III study comparing irinotecan with paclitaxel in patients with advanced gastric cancer without severe peritoneal metastasis after failure of prior combination chemotherapy using fluoropyrimidine plus platinum: WJOG 4007 trial.","J Clin Oncol",2013,"Hironaka et al.",2,[1,4],[14.63,14.63],14.63,10,8,7,[0,0,0,0,1,1,1,0,2,0,0,1,0,0,2,2],"10.1200/JCO.2012.48.5805"],[24395555,"Efficacy of conventional synthetic disease-modifying antirheumatic drugs, glucocorticoids and tofacitinib: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis.","Ann Rheum Dis",2014,"Gaujoux-Viala et al.",0,[11],[14.63],14.63,8,8,7,[0,0,0,2,1,1,1,1,0,0,0,0,0,1,0,1],"10.1136/annrheumdis-2013-204588"],[24423978,"Adrenocortical carcinoma.","Endocr Rev",2014,"Else et al.",6,[7,1],[14.63,12.16],14.63,9,8,7,[0,0,0,0,1,2,1,2,1,1,0,0,1,0,0,0],"10.1210/er.2013-1029"],[24482301,"Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial.","Ann Rheum Dis",2014,"Ritchlin et al.",2,[14,11,13],[14.63,10.68,10.68],14.63,10,8,7,[0,0,0,0,1,1,1,1,2,2,1,0,0,0,0,0],"10.1136/annrheumdis-2013-204655"],[24679061,"Clonidine in patients undergoing noncardiac surgery.","N Engl J Med",2014,"Devereaux et al.",2,[0],[12.16],14.63,13,8,7,[0,0,0,1,0,0,1,1,0,0,0,0,1,2,1,1],"10.1056/NEJMoa1401106"],[24690329,"Comparison of devices for newborn ventilation in the delivery room.","J Pediatr",2014,"Szyld et al.",2,[0,17],[9.17,11.84],14.63,11,8,7,[0,0,0,0,3,1,1,0,1,0,1,0,0,0,1,2],"10.1016/j.jpeds.2014.02.035"],[24696222,"Efficacy of catheter ablation of atrial fibrillation in patients with obstructive sleep apnoea with and without continuous positive airway pressure treatment: a meta-analysis of observational studies.","Europace",2014,"Li et al.",0,[0,5,3],[14.63,1.0,0.0],14.63,15,8,7,[0,1,0,0,0,1,1,1,0,1,1,0,0,4,0,0],"10.1093/europace/euu066"],[24841276,"Comparison of choline-PET/CT, MRI, SPECT, and bone scintigraphy in the diagnosis of bone metastases in patients with prostate cancer: a meta-analysis.","Skeletal Radiol",2014,"Shen et al.",0,[1,9,8],[14.63,14.63,12.16],14.63,10,8,7,[0,0,0,0,0,1,2,0,0,2,1,1,1,2,0,0],"10.1007/s00256-014-1903-9"],[24854611,"Early and/or immediately full caloric diet versus standard refeeding in mild acute pancreatitis: a randomized open-label trial.","Pancreatology",2014,"Lariño-Noia et al.",2,[4],[14.63],14.63,9,8,7,[0,0,0,0,0,0,0,1,0,1,1,1,0,2,1,2],"10.1016/j.pan.2014.02.008"],[25327484,"Vaginal administration of estradiol: effects of dose, preparation and timing on plasma estradiol levels.","Climacteric",2015,"Santen",6,[1,9],[9.02,8.47],14.63,9,8,7,[0,0,0,0,1,2,1,1,1,0,2,0,0,0,0,1],"10.3109/13697137.2014.947254"],[25349290,"Preservation of memory with conformal avoidance of the hippocampal neural stem-cell compartment during whole-brain radiotherapy for brain metastases (RTOG 0933): a phase II multi-institutional trial.","J Clin Oncol",2014,"Gondi et al.",3,[5,1,13],[11.38,14.63,1.35],14.63,10,8,8,[0,0,0,0,0,2,0,1,1,0,0,3,1,1,1,0],"10.1200/JCO.2014.57.2909"],[25467569,"Incidence of infective endocarditis in England, 2000-13: a secular trend, interrupted time-series analysis.","Lancet",2015,"Dayer et al.",5,[0],[12.65],14.63,15,8,7,[0,0,0,0,1,1,2,2,0,0,2,1,0,1,0,0],"10.1016/S0140-6736(14)62007-9"],[25500231,"Net clinical benefit of antithrombotic therapy in patients with atrial fibrillation and chronic kidney disease: a nationwide observational cohort study.","J Am Coll Cardiol",2014,"Bonde et al.",5,[0,5,8],[14.63,5.29,0.0],14.63,14,8,7,[0,0,0,0,2,1,1,2,1,1,0,0,0,2,0,0],"10.1016/j.jacc.2014.09.051"],[25541124,"The incremental risk of noncardiac surgery on adverse cardiac events following coronary stenting.","J Am Coll Cardiol",2014,"Holcomb et al.",5,[0],[12.65],14.63,12,8,8,[0,0,0,0,0,1,1,2,1,0,0,1,1,1,0,0],"10.1016/j.jacc.2014.09.072"],[25636900,"Kommerell's diverticulum in the current era: a comprehensive review.","Gen Thorac Cardiovasc Surg",2015,"Tanaka et al.",6,[0,17,4],[14.63,1.35,0.0],14.63,10,8,7,[0,0,0,0,0,0,0,0,1,1,1,1,2,2,0,1],"10.1007/s11748-015-0521-3"],[25732419,"A meta-analysis of the utility of C-reactive protein, erythrocyte sedimentation rate, fecal calprotectin, and fecal lactoferrin to exclude inflammatory bowel disease in adults with IBS.","Am J Gastroenterol",2015,"Menees et al.",0,[4],[14.63],14.63,10,8,8,[0,0,0,0,1,0,0,1,1,0,2,0,2,2,1,0],"10.1038/ajg.2015.6"],[25913022,"Therapeutic hypothermia after out-of-hospital cardiac arrest in children.","N Engl J Med",2015,"Moler et al.",2,[0,5],[14.63,1.0],14.63,14,10,6,[0,0,0,0,4,0,2,1,1,1,0,0,0,0,3,1],"10.1056/NEJMoa1411480"],[25917786,"Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis.","Gastroenterology",2015,"Brandse et al.",3,[4],[14.63],14.63,11,8,8,[0,0,0,0,0,0,0,1,2,1,0,0,1,2,3,1],"10.1053/j.gastro.2015.04.016"],[26027881,"Elective versus Therapeutic Neck Dissection in Node-Negative Oral Cancer.","N Engl J Med",2015,"D'Cruz et al.",2,[1,16],[14.63,6.77],14.63,10,8,7,[0,0,0,0,0,2,1,1,1,2,1,0,0,0,0,2],"10.1056/NEJMoa1506007"],[26044319,"Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome.","Clin Gastroenterol Hepatol",2015,"Keskin et al.",3,[2,4],[14.63,14.63],14.63,9,8,7,[0,0,0,0,0,0,1,1,1,1,0,2,2,0,0,1],"10.1016/j.cgh.2015.05.029"],[26176382,"CLINICAL PRACTICE. Heparin-Induced Thrombocytopenia.","N Engl J Med",2015,"Greinacher",6,[10],[5.78],14.63,10,8,9,[0,0,0,0,0,1,0,1,0,2,1,0,1,1,0,1],"10.1056/NEJMcp1411910"],[26371143,"Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial.","J Clin Oncol",2016,"Demetri et al.",2,[1],[14.63],14.63,10,8,7,[0,0,0,0,0,1,0,1,0,0,2,1,1,1,3,0],"10.1200/JCO.2015.62.4734"],[26677985,"Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease Than Transient Elastography.","Gastroenterology",2016,"Imajo et al.",5,[4],[14.63],14.63,9,8,8,[0,0,0,0,0,0,0,1,1,0,1,2,0,1,1,1],"10.1053/j.gastro.2015.11.048"],[26705854,"Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis.","Lancet Oncol",2016,"Renehan et al.",5,[1,4],[14.63,14.63],14.63,10,8,7,[0,0,0,0,0,0,1,1,1,1,0,0,0,3,1,1],"10.1016/S1470-2045(15)00467-2"],[26947331,"Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial.","Lancet Oncol",2016,"Cristofanilli et al.",2,[1],[14.63],14.63,10,8,7,[0,0,0,0,0,0,1,1,0,2,1,0,3,0,1,1],"10.1016/S1470-2045(15)00613-0"],[27039970,"Effects of Eradicating Hepatitis C Virus Infection in Patients With Cirrhosis Differ With Stage of Portal Hypertension.","Gastroenterology",2016,"Di Marco et al.",5,[4,2],[14.63,5.78],14.63,8,8,7,[0,0,0,0,0,1,2,0,1,1,1,1,0,1,0,0],"10.1053/j.gastro.2016.03.036"],[27107787,"The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer.","J Thorac Oncol",2016,"Travis et al.",6,[1,3],[14.63,14.63],14.63,9,8,7,[0,0,0,0,0,0,3,1,1,0,0,0,1,1,1,1],"10.1016/j.jtho.2016.03.025"],[27198511,"Analysis of Prognostic Factors from 9387 Merkel Cell Carcinoma Cases Forms the Basis for the New 8th Edition AJCC Staging System.","Ann Surg Oncol",2016,"Harms et al.",7,[1,2,14],[14.63,14.63,14.63],14.63,9,8,7,[0,0,0,0,0,0,0,1,2,0,0,1,1,1,2,1],"10.1245/s10434-016-5266-4"],[27299520,"Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.","Am J Respir Crit Care Med",2016,"Collard et al.",6,[3],[14.63],14.63,14,8,7,[0,0,0,0,0,0,3,1,0,0,2,2,2,1,1,0],"10.1164/rccm.201604-0801CI"],[27367496,"Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations.","JAMA Oncol",2016,"Shu et al.",5,[1,9],[14.63,12.16],14.63,8,8,7,[0,0,0,0,0,0,1,1,0,0,1,1,1,2,1,0],"10.1001/jamaoncol.2016.1820"],[27424812,"Antiretroviral Therapy for the Prevention of HIV-1 Transmission.","N Engl J Med",2016,"Cohen et al.",2,[2,9,12],[13.81,11.38,9.02],14.63,8,8,7,[0,0,0,0,0,0,0,1,1,2,1,1,0,0,1,1],"10.1056/NEJMoa1600693"],[27626365,"Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.","N Engl J Med",2016,"Donovan et al.",2,[8,1,9],[14.63,12.16,12.16],14.63,9,8,7,[0,0,0,0,0,0,0,2,1,1,2,1,0,1,1,0],"10.1056/NEJMoa1606221"],[28129987,"Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial.","Lancet",2017,"Neoptolemos et al.",2,[1,4,7],[14.63,14.63,14.63],14.63,9,8,7,[0,0,0,0,0,0,1,1,1,0,1,0,2,1,1,0],"10.1016/S0140-6736(16)32409-6"],[28131785,"Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial.","Lancet Oncol",2017,"Sharma et al.",3,[1,8],[14.63,12.16],14.63,9,8,7,[0,0,0,0,0,0,1,0,1,1,3,1,1,0,1,0],"10.1016/S1470-2045(17)30065-7"],[28214091,"Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial.","Lancet",2017,"Paramsothy et al.",2,[4],[8.37],14.63,11,8,6,[0,0,0,0,0,0,0,2,1,1,1,0,1,2,1,0],"10.1016/S0140-6736(17)30182-4"],[28376237,"Use of image registration and fusion algorithms and techniques in radiotherapy: Report of the AAPM Radiation Therapy Committee Task Group No. 132.","Med Phys",2017,"Brock et 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randomized double-blind trial of contrast-induced nephropathy in patients with chronic kidney disease.","Circulation",2007,"Solomon et al.",2,[8],[7.22],14.58,18,9,7,[2,3,3,2,1,1,0,0,2,1,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.106.671644"],[17785583,"High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation.","Blood",2007,"Lee et al.",5,[10,1],[14.58,13.47],14.58,11,9,6,[0,1,1,1,0,2,0,0,1,0,2,0,0,2,0,1],"10.1182/blood-2007-06-097386"],[18413399,"Therapeutic administration of 131I for differentiated thyroid cancer: radiation dose to ovaries and outcome of pregnancies.","J Nucl Med",2008,"Garsi et al.",7,[7,1],[14.58,11.05],14.58,10,9,6,[1,1,0,2,1,2,0,0,0,1,0,0,0,0,1,1],"10.2967/jnumed.107.046599"],[18441328,"HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target.","Ann Oncol",2008,"Gravalos et 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Catheter Study Group.","N Engl J Med",1999,"Darouiche et al.",2,[2],[14.44],14.44,9,8,9,[1,1,0,3,1,0,2,0,0,0,0,0,0,0,0,0],"10.1056/NEJM199901073400101"],[10561210,"Oral medroxyprogesterone acetate in the treatment of advanced or recurrent endometrial carcinoma: a dose-response study by the Gynecologic Oncology Group.","J Clin Oncol",1999,"Thigpen et al.",2,[1,9],[14.44,14.44],14.44,8,8,7,[0,2,0,0,0,0,2,0,0,2,0,0,1,0,0,1],"10.1200/JCO.1999.17.6.1736"],[12133178,"Clinical review: complications and risk factors of peripheral arterial catheters used for haemodynamic monitoring in anaesthesia and intensive care medicine.","Crit Care",2002,"Scheer et al.",6,[0,2],[5.39,6.77],14.44,10,8,8,[1,0,0,0,0,0,1,0,0,2,0,0,0,2,3,0],"10.1186/cc1489"],[12873814,"Spironolactone alone or in combination with furosemide in the treatment of moderate ascites in nonazotemic cirrhosis. A randomized comparative study of efficacy and safety.","J Hepatol",2003,"Santos et al.",2,[4],[14.44],14.44,8,8,8,[0,1,0,0,0,0,1,2,0,0,3,0,0,0,1,0],"10.1016/s0168-8278(03)00188-0"],[14999109,"Sequential therapies for proliferative lupus nephritis.","N Engl J Med",2004,"Contreras et al.",2,[11,8],[12.63,6.2],14.44,10,8,9,[0,4,1,0,0,0,0,1,0,0,1,0,0,2,0,0],"10.1056/NEJMoa031855"],[15111519,"Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.","Diabetes Care",2004,"Wild et al.",7,[7],[6.77],14.44,8,8,8,[2,2,2,0,1,1,0,0,0,0,0,0,0,0,0,0],"10.2337/diacare.27.5.1047"],[15134615,"Infectious and healing complications after elective orthopaedic foot and ankle surgery during tumor necrosis factor-alpha inhibition therapy.","Foot Ankle Int",2004,"Bibbo et al.",3,[11],[12.63],14.44,8,8,8,[2,3,0,1,0,0,0,0,1,0,0,0,0,1,0,0],"10.1177/107110070402500510"],[15452780,"Detachable snare versus epinephrine injection in the prevention of postpolypectomy bleeding: a randomized and controlled study.","Endoscopy",2004,"Di Giorgio et al.",2,[4],[14.44],14.44,10,8,9,[2,2,2,0,0,0,0,0,0,1,0,0,0,1,0,0],"10.1055/s-2004-825801"],[16133981,"The value of serum CA 19-9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis.","Dig Dis Sci",2005,"Levy et al.",3,[4,1],[11.85,6.77],14.44,8,8,8,[0,0,2,0,2,0,2,0,1,0,0,0,0,1,0,0],"10.1007/s10620-005-2927-8"],[16207738,"Validation of a model to predict adverse outcomes in patients with pulmonary embolism.","Eur Heart J",2006,"Aujesky et al.",7,[0,3],[14.44,6.2],14.44,8,8,8,[3,0,2,0,0,0,0,1,0,0,1,0,0,1,0,0],"10.1093/eurheartj/ehi588"],[16225482,"Review article: the management of heartburn in pregnancy.","Aliment Pharmacol Ther",2005,"Richter",6,[9],[0.0],14.44,8,8,8,[0,0,0,0,0,2,2,0,0,0,0,1,0,1,2,0],"10.1111/j.1365-2036.2005.02654.x"],[16276167,"Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients.","Crit Care Med",2005,"Nava et al.",2,[3],[14.44],14.44,8,8,8,[1,0,0,1,0,0,3,0,0,1,0,0,0,2,0,0],"10.1097/01.ccm.0000186416.44752.72"],[16279895,"Palliation of nonresectable bile duct cancer: improved survival after photodynamic therapy.","Am J Gastroenterol",2005,"Zoepf et al.",2,[4,1],[14.44,11.85],14.44,10,8,8,[1,1,2,0,0,0,0,0,0,0,0,0,2,3,0,0],"10.1111/j.1572-0241.2005.00318.x"],[16390886,"Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice.","Am J Psychiatry",2006,"Trivedi et al.",3,[6],[14.44],14.44,8,8,8,[0,2,0,0,2,0,0,0,1,0,1,0,2,0,0,0],"10.1176/appi.ajp.163.1.28"],[16670414,"Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis.","JAMA",2006,"Nelson et al.",0,[0,1],[6.2,5.39],14.44,9,8,8,[0,0,0,1,3,0,0,1,0,0,2,0,0,1,0,0],"10.1001/jama.295.17.2057"],[17329193,"Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis.","Lancet Oncol",2007,"Gebski et al.",0,[1,4],[14.44,14.44],14.44,8,8,8,[4,1,1,0,0,0,0,0,0,1,1,0,0,0,0,0],"10.1016/S1470-2045(07)70039-6"],[17565082,"Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery.","JAMA",2007,"Wu et al.",5,[10],[6.2],14.44,8,8,8,[1,0,1,0,2,0,0,0,2,2,0,0,0,0,0,0],"10.1001/jama.297.22.2481"],[17893296,"Electrographic seizures and periodic discharges after intracerebral hemorrhage.","Neurology",2007,"Claassen et al.",5,[5,0],[14.44,12.63],14.44,8,8,8,[0,1,2,2,0,0,0,0,0,0,0,1,0,0,2,0],"10.1212/01.wnl.0000281664.02615.6c"],[18253970,"Nicotine replacement therapy for smoking cessation.","Cochrane Database Syst Rev",2008,"Stead et al.",0,[0],[6.77],14.44,11,8,9,[2,4,1,1,0,1,0,0,0,0,0,0,0,0,0,0],"10.1002/14651858.CD000146.pub3"],[18309168,"Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial.","Stroke",2008,"Smith et al.",3,[0,5],[14.44,14.44],14.44,9,8,8,[1,2,3,1,0,0,0,0,0,0,1,0,0,0,0,0],"10.1161/STROKEAHA.107.497115"],[18407790,"Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study.","Lancet Oncol",2008,"McCredie et al.",5,[9,1],[14.44,11.85],14.44,9,8,9,[0,2,1,0,0,1,0,0,0,3,0,0,1,0,0,0],"10.1016/S1470-2045(08)70103-7"],[18996858,"Weight loss improves the response of obese patients with moderate-to-severe chronic plaque psoriasis to low-dose cyclosporine therapy: a randomized, controlled, investigator-blinded clinical trial.","Am J Clin Nutr",2008,"Gisondi et al.",2,[14,7],[14.44,1.0],14.44,10,8,8,[0,1,0,1,0,0,0,0,3,1,2,0,0,0,0,0],"10.3945/ajcn.2008.26427"],[19005182,"Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group.","Blood",2009,"Rodeghiero et al.",4,[10],[12.63],14.44,10,8,8,[2,2,0,0,0,1,0,0,4,1,0,0,0,0,0,0],"10.1182/blood-2008-07-162503"],[19115222,"Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients.","Hepatology",2009,"Moucari et al.",7,[2,4],[14.44,14.44],14.44,9,8,8,[0,3,2,0,0,2,0,0,1,0,0,0,0,0,1,0],"10.1002/hep.22744"],[19307517,"Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials.","Arch Intern Med",2009,"Bischoff-Ferrari et al.",0,[13],[10.16],14.44,8,8,8,[2,1,0,0,2,0,2,1,0,0,0,0,0,0,0,0],"10.1001/archinternmed.2008.600"],[19325481,"Usefulness of the \"Candida score\" for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: a prospective multicenter study.","Crit Care Med",2009,"León et al.",5,[2],[14.44],14.44,13,10,8,[3,1,3,0,0,2,0,0,1,0,0,0,0,0,0,0],"10.1097/CCM.0b013e31819daa14"],[19364956,"Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study.","J Clin Oncol",2009,"Green et al.",6,[1,7,9],[10.16,2.69,2.69],14.44,8,8,8,[0,2,0,0,0,0,0,0,0,0,1,0,0,3,1,1],"10.1200/JCO.2008.21.1839"],[19364974,"Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association.","Circulation",2009,"Hlatky et al.",7,[0],[12.63],14.44,15,10,8,[3,1,0,1,0,4,0,0,0,0,0,0,0,1,0,0],"10.1161/CIRCULATIONAHA.109.192278"],[19399803,"Reactivation of hepatitis B.","Hepatology",2009,"Hoofnagle",4,[2,4],[14.44,14.44],14.44,9,8,8,[0,3,1,1,0,0,0,0,0,0,1,0,0,0,2,0],"10.1002/hep.22945"],[19410716,"Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial.","Lancet",2009,"Pirker et al.",2,[1,3],[14.44,12.63],14.44,9,8,8,[2,3,2,0,1,0,0,1,0,0,0,0,0,0,0,0],"10.1016/S0140-6736(09)60569-9"],[19682735,"Non-invasive ventilation after extubation in hypercapnic patients with chronic respiratory disorders: randomised controlled trial.","Lancet",2009,"Ferrer et al.",2,[3],[14.44],14.44,8,8,8,[1,0,0,0,0,0,3,0,0,1,1,0,0,2,0,0],"10.1016/S0140-6736(09)61038-2"],[19884472,"Detection of myocardial damage in patients with sarcoidosis.","Circulation",2009,"Patel et al.",3,[10,12],[4.65,4.65],14.44,10,8,8,[0,1,0,1,0,0,0,0,2,3,1,0,0,0,0,0],"10.1161/CIRCULATIONAHA.109.851352"],[20079528,"Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study.","Lancet",2010,"Cannon et al.",2,[0],[14.44],14.44,12,10,7,[4,1,2,0,0,0,0,2,0,0,0,0,0,0,1,0],"10.1016/S0140-6736(09)62191-7"],[20354531,"Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I).","Br J Cancer",2010,"Northover et al.",2,[1,4],[14.44,14.44],14.44,9,8,8,[0,0,0,0,0,0,2,2,0,0,2,0,1,0,2,0],"10.1038/sj.bjc.6605605"],[20567183,"Endometrial thickness measurement for detecting endometrial cancer in women with postmenopausal bleeding: a systematic review and meta-analysis.","Obstet Gynecol",2010,"Timmermans et al.",0,[9,1],[14.44,10.16],14.44,8,8,8,[0,0,3,1,0,0,2,0,0,0,0,0,0,1,0,1],"10.1097/AOG.0b013e3181e3e7e8"],[20628385,"Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan.","Br J Cancer",2010,"Okusaka et al.",2,[1,4],[14.44,14.44],14.44,10,8,8,[0,0,0,0,0,0,0,0,0,1,2,0,3,2,1,0],"10.1038/sj.bjc.6605779"],[20877348,"Rate and predictors of early/missed colorectal cancers after colonoscopy in Manitoba: a population-based study.","Am J Gastroenterol",2010,"Singh et al.",7,[4,1],[14.44,11.85],14.44,8,8,8,[0,2,0,0,0,2,1,0,0,0,1,2,0,0,0,0],"10.1038/ajg.2010.390"],[21571150,"Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).","Lancet",2011,"Wang et al.",2,[10,17],[12.63,12.63],14.44,8,8,8,[0,0,0,3,1,0,0,1,1,0,0,0,0,2,0,0],"10.1016/S0140-6736(11)60355-3"],[21963329,"A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer.","J Thorac Cardiovasc Surg",2011,"Yasufuku et al.",3,[1,3],[14.44,14.44],14.44,8,8,8,[0,0,2,1,0,2,0,0,0,0,0,0,1,0,2,0],"10.1016/j.jtcvs.2011.08.037"],[22042412,"Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model.","Anesthesiology",2012,"Godier et al.",7,[0],[11.85],14.44,10,8,9,[0,0,3,1,1,0,0,3,0,0,0,0,1,0,0,0],"10.1097/ALN.0b013e318238c036"],[23110790,"Omega 3 Fatty acids and cardiovascular outcomes: systematic review and meta-analysis.","Circ Cardiovasc Qual Outcomes",2012,"Kotwal et al.",0,[0],[12.63],14.44,9,8,8,[0,0,0,1,2,1,0,2,0,0,0,0,0,2,0,0],"10.1161/CIRCOUTCOMES.112.966168"],[23301632,"Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up.","Br J Dermatol",2013,"Papp et al.",0,[14],[10.16],14.44,8,8,8,[0,0,0,0,0,0,0,0,3,1,2,1,0,0,1,0],"10.1111/bjd.12214"],[23375693,"Empiric 6-food elimination diet induced and maintained prolonged remission in patients with adult eosinophilic esophagitis: a prospective study on the food cause of the disease.","J Allergy Clin Immunol",2013,"Lucendo et al.",3,[12,4,10],[14.44,11.85,11.85],14.44,8,8,8,[0,0,0,0,0,0,1,0,0,2,1,0,0,2,2,0],"10.1016/j.jaci.2012.12.664"],[23607594,"Sofosbuvir for previously untreated chronic hepatitis C infection.","N Engl J Med",2013,"Lawitz et al.",2,[2,4],[14.44,14.44],14.44,10,8,8,[0,0,0,3,2,3,1,0,0,1,0,0,0,0,0,0],"10.1056/NEJMoa1214853"],[23718152,"Targeted versus universal decolonization to prevent ICU infection.","N Engl J Med",2013,"Huang et al.",2,[2],[14.44],14.44,8,8,8,[0,0,0,3,0,2,0,0,1,0,0,1,0,0,0,1],"10.1056/NEJMoa1207290"],[23954315,"Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner.","Gastroenterology",2013,"Schoepfer et al.",5,[4,10,12],[14.44,14.44,14.44],14.44,8,8,8,[0,0,0,0,0,0,0,1,0,1,0,0,0,3,2,1],"10.1053/j.gastro.2013.08.015"],[24195548,"Dolutegravir plus abacavir-lamivudine for the treatment of HIV-1 infection.","N Engl J Med",2013,"Walmsley et al.",2,[2,9,12],[14.44,14.44,14.44],14.44,10,8,8,[0,0,0,4,3,1,1,0,0,0,0,0,0,0,1,0],"10.1056/NEJMoa1215541"],[24415445,"Lack of difference among terlipressin, somatostatin, and octreotide in the control of acute gastroesophageal variceal hemorrhage.","Hepatology",2014,"Seo et al.",2,[4],[14.44],14.44,8,8,8,[0,0,0,0,0,0,2,1,1,2,0,0,0,0,2,0],"10.1002/hep.27006"],[24777675,"Corticosteroid use and risk of orofacial clefts.","Birth Defects Res A Clin Mol Teratol",2014,"Skuladottir et al.",5,[16,17,13],[1.0,0.0,0.0],14.44,8,8,8,[0,0,0,0,0,1,1,0,0,0,0,0,2,2,2,0],"10.1002/bdra.23248"],[25282284,"Detection of lung cancer through low-dose CT screening (NELSON): a prespecified analysis of screening test performance and interval cancers.","Lancet Oncol",2014,"Horeweg et al.",2,[1,3],[14.44,14.44],14.44,10,8,10,[0,0,0,0,2,0,1,2,0,0,2,0,1,0,0,0],"10.1016/S1470-2045(14)70387-0"],[25342246,"Improving infant outcome with a 10 min Apgar of 0.","Arch Dis Child Fetal Neonatal Ed",2015,"Kasdorf et al.",6,[0],[10.16],14.44,10,8,8,[0,0,0,0,3,1,0,0,0,0,1,0,0,0,2,1],"10.1136/archdischild-2014-306687"],[25372087,"Cost-effectiveness of CT screening in the National Lung Screening Trial.","N Engl J Med",2014,"Black et al.",2,[1,3],[12.63,12.63],14.44,12,8,9,[0,0,0,0,2,1,3,3,0,0,1,0,0,0,0,0],"10.1056/NEJMoa1312547"],[25599346,"Combination antifungal therapy for invasive aspergillosis: a randomized trial.","Ann Intern Med",2015,"Marr et al.",2,[2,1,10],[14.44,1.0,1.0],14.44,8,8,8,[0,0,0,0,0,2,1,0,1,0,1,0,0,0,3,0],"10.7326/M13-2508"],[25981812,"Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials.","Lancet Oncol",2015,"Chang et al.",2,[1,3],[14.44,11.85],14.44,9,8,8,[0,0,0,0,0,1,3,0,0,1,0,0,0,1,3,0],"10.1016/S1470-2045(15)70168-3"],[26242443,"Effect of continuous versus on-demand treatment of ankylosing spondylitis with diclofenac over 2 years on radiographic progression of the spine: results from a randomised multicentre trial (ENRADAS).","Ann Rheum Dis",2016,"Sieper et al.",2,[11,13],[14.44,14.44],14.44,8,8,8,[0,0,0,0,0,0,1,0,3,0,1,0,2,0,1,0],"10.1136/annrheumdis-2015-207897"],[26275735,"Induction chemoradiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial.","Lancet",2015,"Pless et al.",2,[1,3],[14.44,14.44],14.44,9,8,8,[0,0,0,0,0,2,1,0,0,0,0,2,2,0,2,0],"10.1016/S0140-6736(15)60294-X"],[26444692,"Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial.","JAMA",2015,"Young et al.",2,[8],[2.0],14.44,10,8,8,[0,0,0,0,0,0,2,0,0,2,0,1,0,3,1,0],"10.1001/jama.2015.12334"],[26662868,"The efficacy of step-down therapy in adult patients with proton pump inhibitor-responsive oesophageal eosinophilia.","Aliment Pharmacol Ther",2016,"Gómez-Torrijos et al.",5,[4,10,12],[14.44,11.85,11.85],14.44,8,8,8,[0,0,0,0,0,0,0,1,0,1,0,0,1,3,2,0],"10.1111/apt.13496"],[26893500,"The safety of vedolizumab for ulcerative colitis and Crohn's disease.","Gut",2017,"Colombel et al.",7,[2,1],[4.04,0.0],14.44,8,8,8,[0,0,0,0,0,0,0,1,2,1,3,0,0,0,1,0],"10.1136/gutjnl-2015-311079"],[26903335,"Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).","JAMA",2016,"Seymour et al.",4,[2],[8.47],14.44,12,8,8,[0,0,0,0,0,0,2,0,2,3,1,0,0,0,2,0],"10.1001/jama.2016.0288"],[26903336,"Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).","JAMA",2016,"Shankar-Hari et al.",0,[2],[8.47],14.44,11,8,8,[0,0,0,0,0,0,2,2,1,2,0,0,0,0,2,0],"10.1001/jama.2016.0289"],[27063728,"Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection.","Gastroenterology",2016,"Julsgaard et al.",5,[4,9],[9.02,1.0],14.44,9,8,9,[0,0,0,0,0,0,1,0,0,0,2,0,2,1,3,0],"10.1053/j.gastro.2016.04.002"],[27072303,"Clinical Outcomes After Evaluation of Stable Chest Pain by Coronary Computed Tomographic Angiography Versus Usual Care: A Meta-Analysis.","Circ Cardiovasc Imaging",2016,"Bittencourt et al.",0,[0],[14.44],14.44,9,8,8,[0,0,0,0,0,0,1,0,0,1,1,4,0,1,0,0],"10.1161/CIRCIMAGING.115.004419"],[27434443,"Comparison of Clinical Outcomes and Adverse Events Associated With Glucose-Lowering Drugs in Patients With Type 2 Diabetes: A Meta-analysis.","JAMA",2016,"Palmer et al.",0,[7,0],[11.85,4.65],14.44,8,8,8,[0,0,0,0,0,0,2,0,1,1,1,0,0,3,0,0],"10.1001/jama.2016.9400"],[28219692,"Prevention of thromboembolic complications in patients with superficial-vein thrombosis given rivaroxaban or fondaparinux: the open-label, randomised, non-inferiority SURPRISE phase 3b trial.","Lancet Haematol",2017,"Beyer-Westendorf et al.",2,[0,3],[14.44,1.0],14.44,9,8,8,[0,0,0,0,0,0,0,0,1,0,3,1,0,2,1,0],"10.1016/S2352-3026(17)30014-5"],[28536104,"Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study.","BMJ",2017,"Hippisley-Cox et al.",5,[0],[4.65],14.44,8,8,8,[0,0,0,0,0,0,0,1,0,0,1,0,0,2,2,2],"10.1136/bmj.j2099"],[28622419,"The risk of hepatocellular carcinoma decreases after the first 5 years of entecavir or tenofovir in Caucasians with chronic hepatitis B.","Hepatology",2017,"Papatheodoridis et al.",5,[4,1,2],[14.44,2.69,10.16],14.44,8,8,8,[0,0,0,0,0,0,0,0,0,2,2,0,0,1,1,2],"10.1002/hep.29320"],[28884703,"Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care.","Lancet Oncol",2017,"Rietjens et al.",4,[3],[4.65],14.44,9,8,7,[0,0,0,0,0,0,0,0,0,4,0,1,1,0,1,1],"10.1016/S1470-2045(17)30582-X"],[29129576,"Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study.","Lancet Diabetes Endocrinol",2018,"Hundemer et al.",5,[7,0],[4.65,12.63],14.44,11,8,8,[0,0,0,0,0,0,0,0,1,0,0,1,0,4,2,1],"10.1016/S2213-8587(17)30367-4"],[29694685,"Effects of 24 Months of Treatment With Romosozumab Followed by 12 Months of Denosumab or Placebo in Postmenopausal Women With Low Bone Mineral Density: A Randomized, Double-Blind, Phase 2, Parallel Group Study.","J Bone Miner Res",2018,"McClung et al.",2,[7,13],[14.44,14.44],14.44,9,8,8,[0,0,0,0,0,0,0,0,0,1,0,2,3,2,1,0],"10.1002/jbmr.3452"],[30501481,"Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL.","N Engl J Med",2018,"Woyach et al.",2,[1,10],[14.44,14.44],14.44,8,8,8,[0,0,0,0,0,0,0,0,0,0,1,2,0,1,3,1],"10.1056/NEJMoa1812836"],[31162856,"Lung cancer mortality reduction by LDCT screening-Results from the randomized German LUSI trial.","Int J Cancer",2020,"Becker et al.",2,[1,3],[14.44,14.44],14.44,10,8,10,[0,0,0,0,0,0,0,0,0,0,2,0,3,1,1,1],"10.1002/ijc.32486"],[31279902,"The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis.","J Hepatol",2019,"Younossi et al.",0,[4,7],[8.47,8.47],14.44,12,8,10,[0,0,0,0,0,0,0,0,0,0,1,1,0,2,2,2],"10.1016/j.jhep.2019.06.021"],[31529790,"Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes.","Cochrane Database Syst Rev",2019,"Rabe et al.",1,[0,9,5],[4.04,4.65,2.0],14.44,9,8,8,[0,0,0,0,0,0,0,0,0,1,0,1,1,0,3,2],"10.1002/14651858.CD003248.pub4"],[31613151,"Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement.","Am J Respir Crit Care Med",2019,"Graham et al.",7,[3],[6.77],14.44,9,8,9,[0,0,0,0,0,0,0,0,0,2,1,0,2,0,2,1],"10.1164/rccm.201908-1590ST"],[32941794,"Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial.","Lancet Oncol",2020,"Bonvalot et al.",2,[1],[14.44],14.44,8,8,8,[0,0,0,0,0,0,0,0,0,0,2,1,1,0,3,1],"10.1016/S1470-2045(20)30446-0"],[33915090,"Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis.","Lancet Gastroenterol Hepatol",2021,"Ovadia et al.",0,[4,9],[14.44,11.85],14.44,9,8,8,[0,0,0,0,0,0,0,0,0,0,0,1,3,2,1,1],"10.1016/S2468-1253(21)00074-1"],[21844080,"Comparative effectiveness of exercise electrocardiography with or without myocardial perfusion single photon emission computed tomography in women with suspected coronary artery disease: results from the What Is the Optimal Method for Ischemia Evaluation in Women (WOMEN) trial.","Circulation",2011,"Shaw et al.",2,[0],[13.96],14.4,14,11,5,[0,1,2,3,0,0,1,0,1,1,1,1,0,1,0,0],"10.1161/CIRCULATIONAHA.111.029660"],[20818864,"Compression-only CPR or standard CPR in out-of-hospital cardiac arrest.","N Engl J Med",2010,"Svensson et al.",2,[0],[14.39],14.39,14,11,5,[1,1,0,0,4,0,0,0,0,0,2,0,0,1,3,2],"10.1056/NEJMoa0908991"],[34077643,"Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma.","N Engl J Med",2021,"Bajorin et al.",2,[1,8],[14.39,14.39],14.39,13,11,6,[0,0,0,0,0,0,0,0,0,0,0,4,1,3,4,1],"10.1056/NEJMoa2034442"],[31986264,"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.","Lancet",2020,"Huang et al.",7,[2,3],[12.33,12.33],14.36,60,57,50,[0,0,0,0,0,0,0,0,0,44,11,4,1,0,0,0],"10.1016/S0140-6736(20)30183-5"],[11713446,"Venous thromboembolism in childhood: a prospective two-year registry in The Netherlands.","J Pediatr",2001,"van Ommen et al.",7,[0],[11.04],14.33,11,8,7,[1,1,1,1,0,0,0,1,1,2,0,1,0,0,1,0],"10.1067/mpd.2001.118192"],[12106928,"Immediate exercise testing to evaluate low-risk patients presenting to the emergency department with chest pain.","J Am Coll Cardiol",2002,"Amsterdam et al.",5,[0],[14.33],14.33,12,8,6,[1,1,1,2,1,1,0,1,1,1,0,0,0,0,0,0],"10.1016/s0735-1097(02)01968-x"],[14645308,"Effect of magnesium sulfate given for neuroprotection before preterm birth: a randomized controlled trial.","JAMA",2003,"Crowther et al.",2,[9,5,17],[14.33,0.0,0.0],14.33,13,8,6,[1,0,1,1,0,4,1,0,1,1,1,0,0,0,0,1],"10.1001/jama.290.20.2669"],[15858185,"Multidetector-row computed tomography in suspected pulmonary embolism.","N Engl J Med",2005,"Perrier et al.",3,[0,3],[14.33,10.68],14.33,9,8,6,[1,0,0,1,1,1,1,1,1,1,1,0,0,0,0,0],"10.1056/NEJMoa042905"],[16432076,"Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321.","J Clin Oncol",2006,"Barlogie et al.",2,[0,1,10],[14.33,14.33,14.33],14.33,12,8,6,[2,0,2,1,2,0,1,0,0,1,1,1,0,0,0,1],"10.1200/JCO.2005.04.5807"],[16702521,"Value of preoperative ultrasonography in the surgical management of initial and reoperative papillary thyroid cancer.","Arch Surg",2006,"Stulak et al.",5,[1,7],[10.68,14.33],14.33,10,8,6,[1,1,1,0,1,1,0,0,0,1,1,0,1,0,1,0],"10.1001/archsurg.141.5.489"],[17130385,"Safety of exercise training for cardiac patients: results of the French registry of complications during cardiac rehabilitation.","Arch Intern Med",2006,"Pavy et al.",5,[0],[12.44],14.33,11,10,7,[3,2,2,1,0,0,0,0,2,0,0,0,0,1,0,0],"10.1001/archinte.166.21.2329"],[18558665,"Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction.","Ann Oncol",2008,"Dank et al.",2,[1,4],[14.33,14.33],14.33,12,8,6,[2,1,2,1,1,1,0,0,1,0,0,2,0,0,1,0],"10.1093/annonc/mdn166"],[18779469,"Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufficiency with the low-molecular-weight heparin dalteparin: an assessment of safety and pharmacodynamics: the DIRECT study.","Arch Intern Med",2008,"Douketis et al.",3,[0,8],[11.5,0.0],14.33,13,8,7,[1,1,2,0,0,0,1,2,0,1,1,0,0,1,1,0],"10.1001/archinte.168.16.1805"],[19156917,"Outcomes of radical nephroureterectomy: a series from the Upper Tract Urothelial Carcinoma Collaboration.","Cancer",2009,"Margulis et al.",7,[1,8],[14.33,14.33],14.33,13,8,6,[0,1,2,0,2,0,0,1,0,1,1,2,0,1,2,0],"10.1002/cncr.24135"],[19622820,"Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality.","JAMA",2009,"Erqou et al.",0,[0,5],[11.89,0.0],14.33,12,8,6,[1,1,1,0,0,1,0,1,1,0,1,0,0,1,0,1],"10.1001/jama.2009.1063"],[20863956,"Changing mortality in 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al.",1,[1,8],[14.33,14.33],14.33,14,8,7,[0,0,0,0,0,1,1,3,1,1,1,4,0,1,1,0],"10.1016/j.eururo.2014.02.038"],[25117772,"Longer examination time improves detection of gastric cancer during diagnostic upper gastrointestinal endoscopy.","Clin Gastroenterol Hepatol",2015,"Teh et al.",5,[4,1],[14.33,10.04],14.33,10,10,6,[0,0,0,0,0,1,1,0,1,0,2,0,0,0,3,2],"10.1016/j.cgh.2014.07.059"],[25265494,"Combined vemurafenib and cobimetinib in BRAF-mutated melanoma.","N Engl J Med",2014,"Larkin et al.",2,[1,14],[14.33,13.08],14.33,12,8,6,[0,0,0,0,1,1,1,1,2,3,0,1,1,0,1,0],"10.1056/NEJMoa1408868"],[26536169,"Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.","N Engl J Med",2016,"Linehan et al.",7,[1,8],[14.33,14.33],14.33,11,8,6,[0,0,0,0,0,2,1,2,1,1,1,1,1,1,0,0],"10.1056/NEJMoa1505917"],[26995592,"Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of 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al.",0,[9],[12.95],14.29,10,9,7,[0,0,0,0,0,0,0,0,1,2,1,1,1,1,2,0],"10.1016/S0140-6736(10)62233-7"],[22416103,"Does this patient have a severe upper gastrointestinal bleed?","JAMA",2012,"Srygley et al.",6,[4],[14.29],14.29,9,9,6,[0,0,1,0,1,3,0,0,1,0,1,0,1,0,1,0],"10.1001/jama.2012.253"],[22884100,"A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer.","Gastrointest Endosc",2012,"Lian et al.",0,[1,4],[14.29,14.29],14.29,10,9,6,[0,0,0,1,1,0,0,0,1,0,1,0,1,0,1,3],"10.1016/j.gie.2012.06.014"],[26325557,"Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy: A Randomized Clinical Trial.","JAMA",2015,"Bakris et al.",2,[8,7],[8.18,7.47],14.29,10,9,6,[0,0,0,0,0,0,1,0,2,2,1,2,0,1,0,1],"10.1001/jama.2015.10081"],[30280641,"First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer.","N Engl J Med",2018,"Horn et 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CAST (Chinese Acute Stroke Trial) Collaborative Group.","Lancet",1997,"",2,[0,5],[14.28,11.84],14.28,8,7,7,[1,1,1,1,0,0,1,1,0,0,0,1,0,1,0,0],""],[9377912,"Prevention of pulmonary morbidity for patients with Duchenne muscular dystrophy.","Chest",1997,"Bach et al.",5,[3,5,13],[9.48,9.48,4.65],14.28,8,7,8,[1,0,0,1,0,0,1,1,0,0,1,1,0,1,1,0],"10.1378/chest.112.4.1024"],[9482291,"Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema.","Lancet",1998,"Cotter et al.",2,[3],[1.0],14.28,13,7,7,[0,1,1,0,0,1,1,0,1,1,0,0,0,0,1,1],"10.1016/S0140-6736(97)08417-1"],[10335782,"Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial.","Lancet",1999,"Overgaard et al.",2,[1],[14.28],14.28,14,7,8,[2,0,1,1,2,2,2,0,0,0,0,0,0,1,2,0],"10.1016/S0140-6736(98)09201-0"],[10475183,"Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial.","Lancet",1999,"Green et al.",2,[1,14,13],[14.28,14.28,0.0],14.28,9,7,7,[0,0,0,1,1,0,1,1,0,1,0,0,2,1,0,1],"10.1016/S0140-6736(98)12168-2"],[11509059,"Should immunonutrition become routine in critically ill patients? A systematic review of the evidence.","JAMA",2001,"Heyland et al.",0,[2],[8.47],14.28,11,7,7,[1,0,1,1,0,2,1,0,1,0,1,0,0,0,1,0],"10.1001/jama.286.8.944"],[11965271,"Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial.","Lancet",2002,"IONA Study Group",2,[0],[14.28],14.28,13,9,6,[1,3,1,0,0,1,0,1,0,1,0,1,0,1,0,0],"10.1016/S0140-6736(02)08265-X"],[12010907,"Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention.","Circulation",2002,"Rihal et al.",5,[8],[9.48],14.28,11,7,8,[1,1,1,2,0,1,0,1,1,1,0,0,0,0,0,0],"10.1161/01.cir.0000016043.87291.33"],[14668727,"Role of preoperative ultrasonography in the surgical management of patients with thyroid cancer.","Surgery",2003,"Kouvaraki et al.",5,[1,7],[9.93,14.28],14.28,11,10,6,[0,0,0,1,4,1,0,0,1,2,0,0,1,0,1,0],"10.1016/s0039-6060(03)00424-0"],[16123506,"Enteral nutritional support and use of diabetes-specific formulas for patients with diabetes: a systematic review and meta-analysis.","Diabetes Care",2005,"Elia et al.",0,[7],[14.28],14.28,11,7,7,[1,1,1,0,0,1,0,1,0,1,0,1,0,1,0,0],"10.2337/diacare.28.9.2267"],[16128676,"A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention.","Aliment Pharmacol Ther",2005,"Kajander et al.",2,[4],[14.28],14.28,9,7,8,[1,1,1,0,0,1,0,1,0,1,0,1,1,0,0,0],"10.1111/j.1365-2036.2005.02579.x"],[16314767,"Vaginal swabs are the specimens of choice when screening for Chlamydia trachomatis and Neisseria gonorrhoeae: results from a multicenter evaluation of the APTIMA assays for both infections.","Sex Transm Dis",2005,"Schachter et al.",7,[2,9],[14.28,14.28],14.28,10,9,6,[1,1,1,0,1,0,0,0,2,0,1,1,0,0,2,0],"10.1097/01.olq.0000190092.59482.96"],[16830883,"Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis.","Lupus",2006,"Kasitanon et al.",5,[11,8],[14.28,5.08],14.28,9,7,8,[0,1,1,0,1,0,0,1,1,0,1,0,0,1,0,1],"10.1191/0961203306lu2313oa"],[17021321,"Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion.","N Engl J Med",2006,"List et al.",3,[10],[14.28],14.28,11,7,8,[1,1,2,2,1,2,1,0,0,0,1,0,0,0,0,0],"10.1056/NEJMoa061292"],[17399848,"Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment.","J Hepatol",2007,"Rosenberg et al.",7,[14,7],[10.83,0.0],14.28,10,7,7,[0,1,0,0,0,0,1,0,1,1,2,0,1,1,1,0],"10.1016/j.jhep.2007.01.024"],[17446531,"Use of maternal GHb concentration to estimate the risk of congenital anomalies in the offspring of women with prepregnancy diabetes.","Diabetes Care",2007,"Guerin et al.",0,[7,9,17],[11.84,11.84,1.0],14.28,9,7,7,[0,1,1,0,1,0,0,1,0,1,0,1,0,0,1,1],"10.2337/dc07-0278"],[17675317,"Randomised placebo controlled trial of non-invasive ventilation for hypercapnia in cystic fibrosis.","Thorax",2008,"Young et al.",2,[3,4,17],[14.28,3.1,3.1],14.28,10,7,8,[0,1,1,0,0,0,1,0,0,1,0,1,0,2,2,1],"10.1136/thx.2007.082602"],[18256391,"Thrombus aspiration during primary percutaneous coronary intervention.","N Engl J Med",2008,"Svilaas et al.",2,[0],[14.28],14.28,12,9,6,[0,1,2,0,0,1,1,1,0,0,0,1,0,1,1,0],"10.1056/NEJMoa0706416"],[18472366,"EXTRA--a multicenter phase II study of chemoradiation using a 5 day per week oral regimen of capecitabine and intravenous mitomycin C in anal cancer.","Int J Radiat Oncol Biol Phys",2008,"Glynne-Jones et al.",3,[1,4],[14.28,14.28],14.28,9,7,7,[0,1,0,0,0,0,1,1,0,0,1,1,1,0,2,1],"10.1016/j.ijrobp.2007.12.012"],[19224850,"First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy.","J Clin Oncol",2009,"Inoue et al.",3,[1,3],[14.28,14.28],14.28,12,7,10,[0,1,2,1,0,0,1,1,2,0,0,0,1,1,0,0],"10.1200/JCO.2008.18.7658"],[19258557,"Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial.","Ann Intern Med",2009,"Crowther et al.",2,[0],[14.28],14.28,8,7,7,[1,1,1,0,1,1,0,1,0,0,1,0,0,0,1,0],"10.7326/0003-4819-150-5-200903030-00005"],[19468079,"Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause.","Am J Epidemiol",2009,"Prentice et al.",2,[0,1],[12.24,11.84],14.28,9,7,7,[1,1,0,0,2,0,1,1,0,0,1,1,0,0,1,0],"10.1093/aje/kwp115"],[19556163,"Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial.","Lancet Oncol",2009,"Sjöström et al.",5,[7,1],[11.84,1.0],14.28,13,7,9,[1,0,0,1,1,0,1,0,1,2,0,1,1,0,0,0],"10.1016/S1470-2045(09)70159-7"],[19652065,"Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.","J Clin Oncol",2009,"Demetri et al.",2,[1],[14.28],14.28,10,7,7,[0,2,1,1,1,2,0,1,0,0,0,1,0,0,1,0],"10.1200/JCO.2008.21.0088"],[19667264,"Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK.","J Clin Oncol",2009,"Shaw et al.",7,[1,3],[14.28,14.28],14.28,14,7,9,[0,3,1,1,1,0,1,1,1,1,0,0,0,0,0,0],"10.1200/JCO.2009.22.6993"],[20567019,"Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin microspheres radioembolization for liver-limited metastatic colorectal cancer refractory to standard chemotherapy.","J Clin Oncol",2010,"Hendlisz et al.",2,[1,4],[14.28,14.28],14.28,9,7,7,[1,0,1,1,0,0,1,0,1,0,2,0,1,0,0,1],"10.1200/JCO.2010.28.5643"],[20805430,"Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.","Circulation",2010,"James et al.",2,[0,8],[11.84,1.0],14.28,14,9,6,[2,1,2,3,1,1,1,0,0,0,0,0,0,1,0,0],"10.1161/CIRCULATIONAHA.109.933796"],[21062852,"Effectiveness of switching between TNF inhibitors in ankylosing spondylitis: data from the NOR-DMARD register.","Ann Rheum Dis",2011,"Lie et al.",3,[11,13],[14.28,14.28],14.28,9,7,7,[0,1,1,1,0,0,2,1,1,0,0,0,1,0,1,0],"10.1136/ard.2010.131797"],[21081714,"Contemporary diagnostic imaging modalities for the staging and surveillance of melanoma patients: a meta-analysis.","J Natl Cancer Inst",2011,"Xing et al.",0,[1,14],[14.28,14.28],14.28,8,7,7,[0,0,1,0,0,1,0,0,1,1,1,1,0,0,1,1],"10.1093/jnci/djq455"],[21145788,"Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study.","Lancet Oncol",2011,"Kempers et al.",5,[1,4,9],[14.28,14.28,1.55],14.28,12,7,10,[0,0,2,1,1,1,0,1,1,0,0,0,0,1,0,1],"10.1016/S1470-2045(10)70265-5"],[21162697,"Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results of a randomized-withdrawal, placebo-controlled trial.","Curr Med Res Opin",2011,"Schwartz et al.",2,[7,5],[6.77,2.69],14.28,9,7,7,[0,1,2,1,0,0,0,0,1,1,0,1,0,1,1,0],"10.1185/03007995.2010.537589"],[21436241,"Predictive and associative models to identify hospitalized medical patients at risk for VTE.","Chest",2011,"Spyropoulos et al.",7,[0,3],[14.28,3.01],14.28,10,10,10,[0,1,1,1,0,0,0,1,0,4,0,1,0,0,0,1],"10.1378/chest.10-1944"],[21712474,"Swedish two-county trial: impact of mammographic screening on breast cancer mortality during 3 decades.","Radiology",2011,"Tabár et al.",2,[1],[14.28],14.28,10,7,7,[0,1,0,1,1,0,2,2,0,0,1,0,0,1,1,0],"10.1148/radiol.11110469"],[21992121,"Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis.","N Engl J Med",2011,"Richeldi et al.",2,[3],[14.28],14.28,12,7,9,[0,1,1,0,1,1,2,0,0,0,0,1,2,1,0,0],"10.1056/NEJMoa1103690"],[22027398,"Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9.","BMJ",2011,"Lidegaard et al.",5,[0],[12.65],14.28,10,9,6,[0,0,1,1,0,0,1,3,1,1,0,0,0,1,1,0],"10.1136/bmj.d6423"],[22256806,"Bone-density testing interval and transition to osteoporosis in older women.","N Engl J Med",2012,"Gourlay et al.",5,[13,7],[14.28,11.84],14.28,9,7,7,[0,0,0,0,0,1,1,1,0,1,0,1,1,1,2,0],"10.1056/NEJMoa1107142"],[22480758,"Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.","Lancet",2012,"Engert et al.",2,[1,10],[14.28,14.28],14.28,10,7,7,[0,0,1,3,1,0,1,1,0,0,0,1,0,1,0,1],"10.1016/S0140-6736(11)61940-5"],[22644954,"Once daily oral mesalamine compared to conventional dosing for induction and maintenance of remission in ulcerative colitis: a systematic review and meta-analysis.","Inflamm Bowel Dis",2012,"Feagan et al.",0,[4],[14.28],14.28,10,7,8,[0,0,0,0,1,0,2,1,1,1,0,0,2,1,1,0],"10.1002/ibd.23024"],[22820980,"The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology.","J Low Genit Tract Dis",2012,"Darragh et al.",4,[1,9,2],[14.28,11.84,4.65],14.28,9,7,7,[0,1,1,1,0,1,1,0,0,1,0,0,0,0,1,1],"10.1097/LGT.0b013e31825c31dd"],[22894572,"Quality-of-life effects of prostate-specific antigen screening.","N Engl J Med",2012,"Heijnsdijk et al.",7,[1,8,9],[12.24,12.24,12.24],14.28,9,7,7,[0,0,1,2,1,0,0,0,1,1,0,1,1,1,0,0],"10.1056/NEJMoa1201637"],[22951305,"Everolimus-eluting stent versus bare-metal stent in ST-segment elevation myocardial infarction (EXAMINATION): 1 year results of a randomised controlled trial.","Lancet",2012,"Sabate et al.",2,[0],[14.28],14.28,12,9,6,[0,0,0,1,1,2,1,3,1,0,1,1,0,0,0,0],"10.1016/S0140-6736(12)61223-9"],[23558162,"Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials.","BMJ",2013,"He et al.",0,[0],[14.28],14.28,13,10,6,[0,0,0,0,0,1,0,2,2,1,0,0,1,2,1,0],"10.1136/bmj.f1325"],[24297950,"Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma.","J Clin Oncol",2014,"Hutson et al.",2,[1,8],[11.84,11.84],14.28,9,7,7,[0,0,0,2,1,1,1,1,0,1,0,1,0,0,1,0],"10.1200/JCO.2013.50.3961"],[24590644,"Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance).","J Clin Oncol",2014,"Smith et al.",2,[1,8,9],[11.84,9.48,9.48],14.28,9,7,7,[0,0,0,0,0,1,1,1,1,2,0,0,1,0,1,1],"10.1200/JCO.2013.51.6500"],[24637998,"Omitting radiotherapy in early positron emission tomography-negative stage I/II Hodgkin lymphoma is associated with an increased risk of early relapse: Clinical results of the preplanned interim analysis of the randomized EORTC/LYSA/FIL H10 trial.","J Clin Oncol",2014,"Raemaekers et al.",2,[1,10],[14.28,14.28],14.28,8,7,8,[0,0,0,1,1,1,1,1,0,1,0,0,0,1,1,0],"10.1200/JCO.2013.51.9298"],[24718923,"Neuraminidase inhibitors for preventing and treating influenza in adults and children.","Cochrane Database Syst Rev",2014,"Jefferson et al.",0,[2,3],[11.84,11.84],14.28,11,7,7,[0,0,0,0,1,2,0,1,2,0,1,0,2,1,1,0],"10.1002/14651858.CD008965.pub4"],[26198074,"Assessment of Clinical Complete Response After Chemoradiation for Rectal Cancer with Digital Rectal Examination, Endoscopy, and MRI: Selection for Organ-Saving Treatment.","Ann Surg Oncol",2015,"Maas et al.",5,[1,4],[14.28,14.28],14.28,10,7,7,[0,0,0,0,0,0,1,1,0,0,1,1,1,1,2,1],"10.1245/s10434-015-4687-9"],[26628470,"Complete Surgical Excision Is Essential for the Management of Patients With Breast Implant-Associated Anaplastic Large-Cell Lymphoma.","J Clin Oncol",2016,"Clemens et al.",5,[1,10],[11.38,11.38],14.28,10,7,7,[0,0,0,0,0,0,1,1,2,1,1,1,1,0,0,1],"10.1200/JCO.2015.63.3412"],[28126333,"First-line ceritinib versus platinum-based chemotherapy in advanced ALK-rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study.","Lancet",2017,"Soria et al.",2,[1,3],[14.28,12.24],14.28,11,7,8,[0,0,0,0,0,0,1,1,2,1,0,2,2,1,0,1],"10.1016/S0140-6736(17)30123-X"],[28809610,"Phase III Study Comparing a Reduced Dose of Cabazitaxel (20 mg/m2) and the Currently Approved Dose (25 mg/m2) in Postdocetaxel Patients With Metastatic Castration-Resistant Prostate Cancer-PROSELICA.","J Clin Oncol",2017,"Eisenberger et al.",2,[1,8,9],[14.28,14.28,14.28],14.28,10,7,7,[0,0,0,0,0,0,0,0,2,2,1,1,1,1,1,1],"10.1200/JCO.2016.72.1076"],[30280657,"Brigatinib versus Crizotinib in ALK-Positive Non-Small-Cell Lung Cancer.","N Engl J Med",2018,"Camidge et al.",2,[1,3],[14.28,12.24],14.28,10,7,8,[0,0,0,0,0,0,0,1,1,1,1,2,1,2,0,1],"10.1056/NEJMoa1810171"],[21684027,"Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site.","Radiother Oncol",2011,"Blanchard et al.",0,[1],[14.25],14.25,10,9,8,[0,0,0,0,1,4,0,0,0,2,0,0,0,0,3,0],"10.1016/j.radonc.2011.05.036"],[23221186,"Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010.","Infect Control Hosp Epidemiol",2013,"Sievert et al.",7,[2],[12.55],14.25,9,9,8,[0,0,0,3,0,2,2,0,2,0,0,0,0,0,0,0],"10.1086/668770"],[30025734,"A Randomized Trial of the Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Intermediate-Risk Pulmonary Embolism: The OPTALYSE PE Trial.","JACC Cardiovasc Interv",2018,"Tapson et al.",2,[0,3],[14.25,14.25],14.25,11,9,8,[0,0,0,0,0,0,0,0,3,2,0,0,0,0,3,2],"10.1016/j.jcin.2018.04.008"],[30707660,"Gemcitabine and Oxaliplatin Chemotherapy or Surveillance in Resected Biliary Tract Cancer (PRODIGE 12-ACCORD 18-UNICANCER GI): A Randomized Phase III Study.","J Clin Oncol",2019,"Edeline et al.",2,[1,4],[14.25,14.25],14.25,9,9,8,[0,0,0,0,0,0,0,0,0,1,0,0,3,2,3,0],"10.1200/JCO.18.00050"],[31287522,"Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia: A Randomized Clinical Trial.","JAMA",2019,"Ponds et al.",2,[4],[14.25],14.25,9,9,8,[0,0,0,0,0,0,0,0,0,3,2,0,0,1,3,0],"10.1001/jama.2019.8859"],[31355878,"Effect of Standard vs Intensive Blood Pressure Control on the Risk of Recurrent Stroke: A Randomized Clinical Trial and Meta-analysis.","JAMA Neurol",2019,"Kitagawa et al.",7,[0],[14.25],14.25,12,9,8,[0,0,0,0,0,0,0,0,0,0,0,0,1,3,3,3],"10.1001/jamaneurol.2019.2167"],[33560322,"Effect 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al.",3,[1,7],[14.25,13.55],14.25,9,9,8,[0,0,0,0,0,0,0,0,0,0,0,1,0,2,5,1],"10.1016/j.annonc.2021.12.014"],[35468325,"Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial.","Lancet Diabetes Endocrinol",2022,"Gastaldelli et al.",2,[7],[11.85],14.25,12,9,9,[0,0,0,0,0,0,0,0,0,0,0,1,0,2,4,2],"10.1016/S2213-8587(22)00070-5"],[37285865,"Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial.","Lancet",2023,"Agarwal et al.",2,[1,8,9],[14.25,14.25,14.25],14.25,10,9,8,[0,0,0,0,0,0,0,0,0,0,0,0,1,2,5,2],"10.1016/S0140-6736(23)01055-3"],[26330417,"Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR(CT): outcome and resource impacts study.","Eur Heart J",2015,"Douglas et al.",5,[0],[14.23],14.23,11,10,5,[0,0,0,0,0,0,1,1,1,0,1,2,2,1,0,1],"10.1093/eurheartj/ehv444"],[35427471,"Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study.","Lancet Oncol",2022,"Diaz et al.",2,[1,4],[14.17,13.68],14.17,11,11,8,[0,0,0,0,0,0,0,0,0,0,0,0,4,3,4,0],"10.1016/S1470-2045(22)00197-8"],[36791160,"Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults.","N Engl J Med",2023,"Papi et al.",2,[2,3],[9.52,3.68],14.17,11,11,10,[0,0,0,0,0,0,0,0,0,0,0,0,1,0,5,5],"10.1056/NEJMoa2209604"],[17928994,"Strict versus moderate glucose control after resuscitation from ventricular fibrillation.","Intensive Care Med",2007,"Oksanen et al.",2,[0],[11.67],14.15,12,10,6,[1,0,1,0,5,0,0,0,0,0,1,0,0,1,2,0],"10.1007/s00134-007-0876-8"],[2070995,"Endoscopic sphincterotomy complications and their management: an attempt at consensus.","Gastrointest Endosc",1991,"Cotton et al.",6,[4,2],[14.13,0.0],14.13,11,10,5,[0,1,0,1,0,2,1,1,1,0,0,1,1,0,0,1],"10.1016/s0016-5107(91)70740-2"],[12354984,"Hemodialysis arteriovenous fistula maturity: US evaluation.","Radiology",2002,"Robbin et al.",7,[8,0],[7.22,5.41],14.13,10,8,6,[0,1,0,1,0,1,1,1,0,2,0,1,0,1,1,0],"10.1148/radiol.2251011367"],[12771115,"Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial.","JAMA",2003,"Young et al.",2,[0],[14.13],14.13,14,11,6,[0,2,5,0,1,0,0,0,2,0,0,0,1,0,0,0],"10.1001/jama.289.20.2685"],[14530225,"Magnetic resonance cholangiopancreatography: a meta-analysis of test performance in suspected biliary disease.","Ann Intern Med",2003,"Romagnuolo et al.",0,[4],[13.38],14.13,9,9,7,[0,2,2,0,0,0,0,0,1,0,0,0,1,0,3,0],"10.7326/0003-4819-139-7-200310070-00006"],[16258899,"Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial.","Arthritis Rheum",2005,"Goekoop-Ruiterman et al.",2,[11],[14.13],14.13,9,8,6,[0,1,1,1,1,0,1,0,1,1,0,0,0,1,0,1],"10.1002/art.21405"],[16484350,"Acute massive gastrointestinal bleeding: detection and localization with arterial phase multi-detector row helical CT.","Radiology",2006,"Yoon et al.",5,[4],[14.13],14.13,9,9,7,[0,0,3,0,3,1,1,0,0,0,1,0,0,0,0,0],"10.1148/radiol.2383050175"],[17761591,"Saline or albumin for fluid resuscitation in patients with traumatic brain injury.","N Engl J Med",2007,"Myburgh et al.",2,[5,13],[4.04,4.65],14.13,9,9,6,[0,0,0,0,4,1,1,2,0,0,0,0,0,1,0,0],"10.1056/NEJMoa067514"],[17971818,"The CYP2D6 activity score: translating genotype information into a qualitative measure of 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al.",5,[0,17],[14.13,5.08],14.13,21,8,6,[0,0,0,1,0,2,1,1,1,1,1,1,0,0,0,1],"10.1161/CIRCULATIONAHA.109.928481"],[21560202,"Development of the Crohn's disease digestive damage score, the Lémann score.","Inflamm Bowel Dis",2011,"Pariente et al.",7,[4],[14.13],14.13,9,8,6,[0,0,1,1,0,0,1,1,1,1,0,0,1,1,1,0],"10.1002/ibd.21506"],[23143546,"Outcomes of noncardiac, nonobstetric surgery in patients with PAH: an international prospective survey.","Eur Respir J",2013,"Meyer et al.",5,[0,3],[14.13,5.08],14.13,19,8,6,[0,0,0,1,2,1,1,1,0,0,1,0,1,1,0,1],"10.1183/09031936.00089212"],[23147400,"Fasting time and lipid levels in a community-based population: a cross-sectional study.","Arch Intern Med",2012,"Sidhu et al.",5,[7],[11.04],14.13,14,8,6,[0,0,0,0,1,2,1,1,1,0,1,1,0,1,0,1],"10.1001/archinternmed.2012.3708"],[23154552,"Local ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene-addicted non-small-cell lung cancer.","J Thorac 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multicentre, randomised, controlled clinical trial.","Lancet Respir Med",2014,"Köhnlein et al.",2,[3],[14.13],14.13,11,9,7,[0,0,0,0,0,0,3,0,0,3,1,1,0,0,3,0],"10.1016/S2213-2600(14)70153-5"],[25415163,"Transgender men who experienced pregnancy after female-to-male gender transitioning.","Obstet Gynecol",2014,"Light et al.",5,[6,9],[1.0,1.0],14.13,9,9,7,[0,0,0,0,0,0,3,0,0,0,1,1,0,2,0,2],"10.1097/AOG.0000000000000540"],[25589192,"Adjuvant chemotherapy after preoperative (chemo)radiotherapy and surgery for patients with rectal cancer: a systematic review and meta-analysis of individual patient data.","Lancet Oncol",2015,"Breugom et al.",0,[1,4],[14.13,14.13],14.13,10,9,7,[0,0,0,0,0,0,4,2,0,0,0,0,0,1,1,1],"10.1016/S1470-2045(14)71199-4"],[25877855,"Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study.","Lancet Oncol",2015,"Tabernero et al.",2,[1,4],[14.13,12.03],14.13,12,8,6,[0,0,0,0,0,0,2,2,1,1,1,0,2,1,1,1],"10.1016/S1470-2045(15)70127-0"],[26135703,"Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet",2015,"McInnes et al.",2,[14,11,13],[14.13,9.17,9.17],14.13,10,9,7,[0,0,0,0,0,2,0,3,2,1,1,0,0,0,0,0],"10.1016/S0140-6736(15)61134-5"],[27844477,"Videolaryngoscopy versus direct laryngoscopy for adult patients requiring tracheal intubation.","Cochrane Database Syst Rev",2016,"Lewis et al.",0,[7],[1.0],14.13,9,9,7,[0,0,0,0,0,0,0,2,0,3,0,2,0,1,1,0],"10.1002/14651858.CD011136.pub2"],[28304242,"Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients.","N Engl J Med",2017,"Ridker et al.",2,[7,0],[12.32,9.87],14.13,9,9,7,[0,0,0,0,0,0,1,1,4,0,2,0,0,0,1,0],"10.1056/NEJMoa1701488"],[28620111,"Dietary Fats 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Results of a Veterans Administration Cooperative Study.","N Engl J Med",1986,"Cohn et al.",2,[0],[14.1],14.1,16,9,6,[0,1,1,1,0,2,2,0,1,0,2,0,0,0,0,0],"10.1056/NEJM198606123142404"],[8047806,"A prospective study of first attacks of inflammatory bowel disease and infectious colitis. 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A new proposal based on a two-institution experience on 703 consecutive N+ patients treated with radical prostatectomy, extended pelvic lymph node dissection and adjuvant therapy.","Eur Urol",2009,"Briganti et al.",5,[1,8,9],[14.1,14.1,14.1],14.1,9,9,6,[0,2,1,1,0,1,0,0,0,1,0,1,0,2,0,0],"10.1016/j.eururo.2008.09.043"],[18848382,"Radical nephrectomy with and without lymph-node dissection: final results of European Organization for Research and Treatment of Cancer (EORTC) randomized phase 3 trial 30881.","Eur Urol",2009,"Blom et al.",2,[1,8],[14.1,14.1],14.1,12,7,6,[1,0,1,1,0,1,2,1,1,1,0,1,0,1,1,0],"10.1016/j.eururo.2008.09.052"],[19001195,"Global secondary prevention strategies to limit event recurrence after myocardial infarction: results of the GOSPEL study, a multicenter, randomized controlled trial from the Italian Cardiac Rehabilitation Network.","Arch Intern Med",2008,"Giannuzzi et al.",2,[0],[14.1],14.1,22,11,7,[1,4,2,0,0,3,0,0,0,1,0,0,2,0,1,0],"10.1001/archinte.168.20.2194"],[19504611,"Endoscopy and MR enteroclysis: equivalent tools in predicting clinical recurrence in patients with Crohn's disease after ileocolic resection.","Inflamm Bowel Dis",2010,"Koilakou et al.",3,[4],[14.1],14.1,9,9,6,[0,0,1,2,0,0,2,1,1,0,0,0,0,1,1,0],"10.1002/ibd.21003"],[19786682,"A randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes: the Sleep AHEAD study.","Arch Intern Med",2009,"Foster et al.",2,[7,3,5],[10.15,4.65,4.65],14.1,13,9,6,[0,0,1,1,0,1,0,2,0,0,0,2,1,0,0,1],"10.1001/archinternmed.2009.266"],[20048269,"Systematic review: prediction of perioperative cardiac complications and mortality by the revised cardiac risk index.","Ann Intern Med",2010,"Ford et al.",0,[0],[12.76],14.1,15,9,6,[0,0,0,2,2,0,1,1,0,0,0,0,1,2,1,0],"10.7326/0003-4819-152-1-201001050-00007"],[20858880,"Subclinical hypothyroidism and the risk of coronary heart disease and mortality.","JAMA",2010,"Rodondi et al.",5,[7,0],[9.29,2.69],14.1,10,9,6,[1,1,3,1,0,1,0,0,1,0,0,0,0,1,0,0],"10.1001/jama.2010.1361"],[21446209,"Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: a meta-analysis.","Obstet Gynecol",2011,"Berghella et al.",0,[9],[14.1],14.1,13,9,6,[0,1,2,1,0,2,0,0,2,3,0,0,0,0,0,1],"10.1097/AOG.0b013e31820ca847"],[21795446,"A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial.","J Clin Endocrinol Metab",2011,"Fidler et al.",2,[7],[11.05],14.1,10,9,6,[0,0,1,2,2,1,1,1,1,0,0,0,0,0,0,0],"10.1210/jc.2011-1256"],[22199119,"Reference values for exercise limitations among adults with congenital heart disease. 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Plasminogen activator Italian multicenter study 2.","J Am Coll Cardiol",1992,"Dalla-Volta et al.",2,[0,3],[14.06,11.58],14.06,9,8,7,[2,1,0,1,0,0,0,0,1,2,2,0,0,0,0,0],"10.1016/0735-1097(92)90002-5"],[2301439,"Prospective, controlled study of vinyl glove use to interrupt Clostridium difficile nosocomial transmission.","Am J Med",1990,"Johnson et al.",3,[2,4],[14.06,0.0],14.06,8,8,7,[0,0,0,1,1,1,0,3,0,1,0,0,0,1,0,0],"10.1016/0002-9343(90)90462-m"],[4693931,"Relations between pancreatic enzyme outputs and malabsorption in severe pancreatic insufficiency.","N Engl J Med",1973,"DiMagno et al.",7,[4,7],[14.06,2.69],14.06,8,8,7,[0,1,1,1,1,1,0,0,0,0,0,0,0,0,3,0],"10.1056/NEJM197304192881603"],[7428736,"Crohn's disease of the stomach and duodenum: A clinical study with emphasis on the value of endoscopy and endoscopic biopsies.","Endoscopy",1980,"Rutgeerts et al.",7,[4],[14.06],14.06,9,8,7,[0,0,1,1,1,0,0,2,1,0,0,0,0,0,3,0],"10.1055/s-2007-1021762"],[8094895,"Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop.","Neurology",1993,"Román et al.",7,[6,5,0],[14.06,12.16,4.65],14.06,9,8,7,[0,3,0,1,0,0,0,1,1,1,0,0,0,0,2,0],"10.1212/wnl.43.2.250"],[8129773,"Nomenclature of systemic vasculitides. Proposal of an international consensus conference.","Arthritis Rheum",1994,"Jennette et al.",4,[0,11],[10.26,10.83],14.06,9,8,7,[2,0,0,0,0,2,0,1,0,0,0,1,1,0,0,1],"10.1002/art.1780370206"],[8150347,"Frequency of glucocorticoid resistance and dependency in Crohn's disease.","Gut",1994,"Munkholm et al.",5,[4],[14.06],14.06,9,8,7,[4,0,1,0,0,0,1,1,1,0,0,0,0,0,1,0],"10.1136/gut.35.3.360"],[8174958,"Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience.","Gut",1993,"Connell et al.",7,[10,4],[0.0,9.77],14.06,9,8,7,[2,2,0,0,0,0,1,2,0,0,0,0,0,0,1,1],"10.1136/gut.34.8.1081"],[8531970,"A comparison of fecal occult-blood tests for colorectal-cancer screening.","N Engl J Med",1996,"Allison et al.",7,[1,4],[14.06,14.06],14.06,8,8,7,[0,3,1,0,0,1,1,1,0,0,1,0,0,0,0,0],"10.1056/NEJM199601183340304"],[8841191,"Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2.","Nat Genet",1996,"Roa et al.",7,[1,7],[14.06,9.77],14.06,8,8,7,[0,0,1,2,2,1,1,0,0,0,0,0,1,0,0,0],"10.1038/ng1096-185"],[8996041,"Upper-extremity deep vein thrombosis. Risk factors, diagnosis, and complications.","Arch Intern Med",1997,"Prandoni et al.",7,[0,11],[14.06,0.0],14.06,9,8,7,[1,4,1,0,0,0,0,1,0,0,0,0,0,1,0,1],""],[9048514,"Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study.","Am J Epidemiol",1997,"Manzi et al.",5,[0,11],[5.29,4.65],14.06,10,8,8,[0,2,0,0,1,0,0,0,2,0,0,1,0,0,1,1],"10.1093/oxfordjournals.aje.a009122"],[9293612,"Valaciclovir versus acyclovir in the treatment of first-episode genital herpes infection. Results of an international, multicenter, double-blind, randomized clinical trial. The Valaciclovir International Herpes Simplex Virus Study Group.","Sex Transm Dis",1997,"Fife et al.",2,[2,9,8],[14.06,14.06,7.47],14.06,8,8,7,[1,0,0,0,1,0,1,0,0,0,1,0,0,0,3,1],"10.1097/00007435-199709000-00007"],[9337824,"Effect of long-term oxygen therapy on survival in patients with chronic obstructive pulmonary disease with moderate hypoxaemia.","Thorax",1997,"Górecka et al.",2,[3],[14.06],14.06,8,8,7,[2,1,0,2,1,0,1,0,0,0,0,0,0,1,0,0],"10.1136/thx.52.8.674"],[9545358,"A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators.","N Engl J Med",1998,"Ouriel et al.",2,[0],[14.06],14.06,14,8,7,[3,2,0,1,0,0,2,0,0,1,0,0,0,1,0,0],"10.1056/NEJM199804163381603"],[9636868,"Amphotericin B lipid complex for invasive fungal infections: analysis of safety and efficacy in 556 cases.","Clin Infect Dis",1998,"Walsh et al.",3,[2],[14.06],14.06,10,10,6,[1,2,1,2,0,2,0,0,2,0,0,0,0,0,0,0],"10.1086/516353"],[9823902,"Classification of adenocarcinoma of the oesophagogastric junction.","Br J Surg",1998,"Siewert et al.",7,[1,4],[9.02,14.06],14.06,8,8,7,[0,1,0,0,1,0,1,0,0,0,0,0,1,2,2,0],"10.1046/j.1365-2168.1998.00940.x"],[10329031,"A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study.","Gynecol Oncol",1999,"Sedlis et al.",2,[1,9],[11.58,11.58],14.06,8,8,7,[0,1,1,0,0,1,0,0,0,2,0,1,0,0,2,0],"10.1006/gyno.1999.5387"],[10896648,"Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial.","Ann Intern Med",2000,"Ross et al.",2,[7],[8.47],14.06,9,8,8,[2,2,2,0,0,1,0,0,1,0,0,1,0,0,0,0],"10.7326/0003-4819-133-2-200007180-00008"],[10900275,"Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings.","N Engl J Med",2000,"Imperiale et al.",5,[1,4],[14.06,14.06],14.06,8,8,7,[1,1,2,0,0,0,1,0,0,1,0,0,0,2,0,0],"10.1056/NEJM200007203430302"],[10950041,"Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case-control study.","Am J Gastroenterol",2000,"Felder et al.",5,[4],[14.06],14.06,11,8,8,[2,0,2,0,1,0,0,3,0,1,0,0,0,0,2,0],"10.1111/j.1572-0241.2000.02262.x"],[11078768,"Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of Clot in This Pregnancy Study Group.","N Engl J Med",2000,"Brill-Edwards et al.",3,[0,9],[14.06,10.83],14.06,9,8,7,[1,3,2,1,0,1,0,1,0,0,0,0,0,0,0,0],"10.1056/NEJM200011163432002"],[11115829,"Management and outcome of pregnancy in autoimmune hepatitis.","Gut",2001,"Heneghan et al.",5,[4,9],[12.16,4.04],14.06,8,8,7,[1,0,0,0,2,2,1,0,0,0,1,0,1,0,0,0],"10.1136/gut.48.1.97"],[11709511,"Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease.","Gut",2001,"Louis et al.",5,[4],[14.06],14.06,8,8,7,[0,0,1,1,1,0,1,0,0,0,0,0,0,1,3,0],"10.1136/gut.49.6.777"],[11867407,"Morbid obesity and tracheal intubation.","Anesth Analg",2002,"Brodsky et al.",7,[7],[9.77],14.06,8,8,7,[0,0,1,1,1,0,0,2,0,0,0,1,0,0,2,0],"10.1097/00000539-200203000-00047"],[11920411,"A double-blind, randomized, placebo-controlled study of cevimeline in Sjögren's syndrome patients with xerostomia and keratoconjunctivitis sicca.","Arthritis Rheum",2002,"Petrone et al.",2,[16,15,11],[7.97,5.78,3.74],14.06,8,8,7,[2,0,0,2,1,0,1,0,1,0,0,0,0,0,1,0],"10.1002/art.510"],[12090880,"Preoperative or postoperative start of prophylaxis for venous thromboembolism with low-molecular-weight heparin in elective hip surgery?","Arch Intern Med",2002,"Strebel et al.",0,[0],[14.06],14.06,9,8,7,[1,2,2,0,1,0,0,2,0,0,0,1,0,0,0,0],"10.1001/archinte.162.13.1451"],[12181401,"Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.","N Engl J Med",2002,"Demetri et al.",2,[1,4],[14.06,9.02],14.06,8,8,7,[0,1,2,1,0,1,0,0,1,0,0,0,0,2,0,0],"10.1056/NEJMoa020461"],[12186604,"Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.","JAMA",2002,"Annane et al.",2,[2,7],[10.26,2.69],14.06,14,8,7,[1,0,2,0,0,2,2,0,0,2,0,0,0,0,1,0],"10.1001/jama.288.7.862"],[12473883,"A randomized, controlled trial of fibrin glue vs. conventional treatment for anal fistula.","Dis Colon Rectum",2002,"Lindsey et al.",2,[4],[14.06],14.06,9,8,7,[2,0,0,2,0,1,0,1,0,2,1,0,0,0,0,0],"10.1007/s10350-004-7247-0"],[12530483,"Acyclovir suppression to prevent recurrent genital herpes at delivery.","Infect Dis Obstet Gynecol",2002,"Scott et al.",2,[2,9,8],[14.06,14.06,9.17],14.06,8,8,7,[1,0,0,0,1,0,2,0,0,0,1,0,0,0,2,1],"10.1155/S1064744902000054"],[12588812,"Management of simple nodular goiter: current status and future perspectives.","Endocr Rev",2003,"Hegedüs et al.",6,[7],[14.06],14.06,8,8,7,[2,0,1,2,0,1,0,0,0,1,0,0,1,0,0,0],"10.1210/er.2002-0016"],[12706636,"An open-label randomized controlled trial of low molecular weight heparin compared to heparin and coumadin for the treatment of venous thromboembolic events in children: the REVIVE trial.","Thromb Res",2003,"Massicotte et al.",2,[0,3],[14.06,0.0],14.06,8,8,7,[1,1,1,0,2,0,0,2,0,0,0,0,0,1,0,0],"10.1016/s0049-3848(03)00059-8"],[12782566,"Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction.","Circulation",2003,"Sweeney et al.",7,[0],[14.06],14.06,20,12,5,[2,1,1,0,0,2,0,0,2,0,0,0,1,1,1,1],"10.1161/01.CIR.0000072769.17295.B1"],[14555255,"Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial.","Bone",2003,"Delmas et al.",2,[13],[11.38],14.06,11,8,7,[1,0,3,0,0,0,2,0,2,0,0,2,0,0,1,0],"10.1016/s8756-3282(03)00241-2"],[14583691,"The Patient Health Questionnaire-2: validity of a two-item depression screener.","Med Care",2003,"Kroenke et al.",7,[6],[2.0],14.06,10,8,7,[1,0,0,0,0,1,1,1,0,0,0,0,2,2,0,0],"10.1097/01.MLR.0000093487.78664.3C"],[14614170,"Opioid therapy for chronic pain.","N Engl J Med",2003,"Ballantyne et al.",6,[6],[10.26],14.06,9,8,7,[2,1,1,2,0,1,1,0,0,0,0,0,0,0,0,0],"10.1056/NEJMra025411"],[14699483,"The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients.","Gastroenterology",2004,"Colombel et al.",5,[4],[14.06],14.06,8,8,7,[1,2,0,2,0,0,1,0,0,0,1,0,0,1,0,0],"10.1053/j.gastro.2003.10.047"],[14723609,"Systematic review: short-term adverse effects of 5-aminosalicylic acid agents in the treatment of ulcerative colitis.","Aliment Pharmacol Ther",2004,"Loftus et al.",1,[4],[14.06],14.06,9,8,7,[1,2,0,0,2,0,2,1,0,0,0,0,0,0,1,0],"10.1111/j.0269-2813.2004.01827.x"],[14724164,"A prospective study of colonoscopy practice in the UK today: are we adequately prepared for national colorectal cancer screening tomorrow?","Gut",2004,"Bowles et al.",5,[4],[14.06],14.06,11,8,7,[0,3,1,0,0,2,0,0,0,0,1,1,0,1,0,0],"10.1136/gut.2003.016436"],[14762036,"Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke.","JAMA",2004,"Levine et al.",2,[0,5],[7.47,5.29],14.06,8,8,7,[2,2,1,1,0,1,0,0,0,1,0,0,0,0,0,0],"10.1001/jama.291.5.576"],[15143088,"Low molecular weight heparin, therapy with dalteparin, and survival in 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A systematic review of randomized controlled trials.","Br J Haematol",2004,"Stanworth et al.",1,[10,4,8],[8.47,0.0,0.0],14.06,10,8,7,[1,2,1,0,0,0,0,2,1,0,0,1,0,0,0,0],"10.1111/j.1365-2141.2004.04973.x"],[15301325,"Effect of an intensive glucose management protocol on the mortality of critically ill adult patients.","Mayo Clin Proc",2004,"Krinsley",3,[7],[6.77],14.06,12,8,7,[1,2,2,0,2,0,0,1,0,0,0,0,1,0,0,0],"10.4065/79.8.992"],[15364803,"Single-arm study of bridging therapy with low-molecular-weight heparin for patients at risk of arterial embolism who require temporary interruption of warfarin.","Circulation",2004,"Kovacs et al.",3,[0],[10.83],14.06,9,8,7,[0,2,2,0,1,0,0,2,0,0,0,1,1,0,0,0],"10.1161/01.CIR.0000142859.77578.C9"],[15556670,"A review of the current use of magnetic resonance imaging in pregnancy and safety implications for the fetus.","Prog Biophys Mol Biol",2005,"De Wilde et al.",6,[9,0],[12.63,5.78],14.06,9,8,7,[3,2,1,1,0,1,0,0,0,0,0,0,0,1,0,0],"10.1016/j.pbiomolbio.2004.08.010"],[16099293,"Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911).","Lancet",2005,"Bolla et al.",2,[1,8,9],[14.06,14.06,14.06],14.06,10,8,7,[1,0,4,1,0,0,0,1,1,0,0,0,0,0,0,1],"10.1016/S0140-6736(05)67101-2"],[16186525,"Prevention of venous thrombosis in patients with acute intracerebral hemorrhage.","Neurology",2005,"Lacut et al.",2,[0,5],[14.06,9.77],14.06,9,8,7,[1,0,2,2,1,0,0,1,0,0,0,0,0,0,1,0],"10.1212/01.wnl.0000176073.80532.a2"],[16322960,"Factors affecting the successful management of intra-abdominal abscesses with antibiotics and the need for percutaneous drainage.","Dis Colon Rectum",2006,"Kumar et al.",5,[2],[2.69],14.06,9,8,7,[0,1,0,2,1,1,0,0,0,2,0,0,0,0,1,0],"10.1007/s10350-005-0274-7"],[16361045,"Eosinophilic esophagitis: a 10-year experience in 381 children.","Clin Gastroenterol Hepatol",2005,"Liacouras et al.",3,[4,10],[14.06,14.06],14.06,8,8,7,[0,0,1,1,0,0,0,0,0,1,0,0,0,3,1,1],"10.1016/s1542-3565(05)00885-2"],[16365182,"Postoperative surveillance in patients with colorectal cancer who have undergone curative resection: a prospective, multicenter, randomized, controlled trial.","J Clin Oncol",2006,"Rodríguez-Moranta et al.",2,[1,4],[14.06,14.06],14.06,10,8,9,[2,0,2,0,1,1,0,0,0,0,1,0,0,1,0,0],"10.1200/JCO.2005.02.0826"],[16575739,"A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS.","Clin Infect Dis",2006,"Vazquez et al.",2,[2,12],[14.06,4.65],14.06,10,8,7,[1,3,2,0,0,2,0,0,1,0,0,0,0,1,0,0],"10.1086/501457"],[16618956,"Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians.","Ann Intern Med",2006,"Smetana et al.",1,[3],[2.69],14.06,8,8,7,[1,1,2,1,0,2,0,0,0,0,0,1,0,0,0,0],"10.7326/0003-4819-144-8-200604180-00009"],[16648499,"Dose-response in radiotherapy for localized prostate cancer: results of the Dutch multicenter randomized phase III trial comparing 68 Gy of radiotherapy with 78 Gy.","J Clin Oncol",2006,"Peeters et al.",2,[1,8,9],[14.06,11.58,11.58],14.06,8,8,7,[1,0,3,1,1,1,0,0,0,0,0,0,0,1,0,0],"10.1200/JCO.2005.05.2530"],[16673310,"Cholangioscopic characterization of dominant bile duct stenoses in patients with primary sclerosing cholangitis.","Endoscopy",2006,"Tischendorf et al.",7,[4],[14.06],14.06,9,8,7,[0,0,2,0,2,0,0,1,1,1,0,0,1,0,0,0],"10.1055/s-2006-925257"],[16683220,"Thrombolytic therapy in pregnancy.","J Thromb Thrombolysis",2006,"Leonhardt et al.",6,[0,9,5],[14.06,11.38,0.0],14.06,9,8,7,[1,2,0,3,1,1,0,0,0,0,1,0,0,0,0,0],"10.1007/s11239-006-5709-z"],[16738270,"Body-mass index and symptoms of gastroesophageal reflux in women.","N Engl J Med",2006,"Jacobson et al.",5,[4,7],[14.06,0.0],14.06,8,8,7,[1,0,0,0,1,1,0,0,0,0,0,2,0,1,2,0],"10.1056/NEJMoa054391"],[16850002,"Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock.","Crit Care Med",2006,"Pontes-Arruda et al.",2,[2,3],[6.77,4.65],14.06,11,8,7,[2,0,1,1,0,1,0,0,2,1,0,0,0,0,0,0],"10.1097/01.CCM.0000234033.65657.B6"],[16931170,"Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease.","Clin Gastroenterol Hepatol",2006,"Maser et al.",5,[4],[14.06],14.06,8,8,7,[1,0,1,0,2,0,2,0,0,0,1,0,0,0,1,0],"10.1016/j.cgh.2006.06.025"],[16939737,"The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants.","J Pediatr",2006,"Kirpalani et al.",2,[10,17],[2.69,2.69],14.06,8,8,7,[0,0,1,0,1,1,0,0,1,0,0,0,0,3,1,0],"10.1016/j.jpeds.2006.05.011"],[17101314,"A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis.","Gastroenterology",2006,"Konikoff et al.",2,[4,10],[14.06,14.06],14.06,8,8,7,[0,0,1,1,0,0,1,0,0,2,0,0,0,2,1,0],"10.1053/j.gastro.2006.08.033"],[17114801,"Influenza vaccination as model for testing immune modulation induced by anti-TNF and methotrexate therapy in rheumatoid arthritis patients.","Rheumatology (Oxford)",2007,"Kapetanovic et al.",7,[11],[14.06],14.06,8,8,7,[3,1,1,0,0,1,0,0,1,0,0,0,0,0,0,1],"10.1093/rheumatology/kel366"],[17122590,"Improved postoperative outcomes associated with preoperative statin therapy.","Anesthesiology",2006,"Hindler et al.",0,[0],[10.83],14.06,10,8,7,[3,1,0,1,2,0,1,0,0,0,0,1,0,0,0,0],"10.1097/00000542-200612000-00027"],[17185072,"Curative endoscopic resection of early esophageal adenocarcinomas (Barrett's cancer).","Gastrointest Endosc",2007,"Ell et al.",5,[1,4],[12.16,14.06],14.06,8,8,7,[0,1,1,1,2,0,0,0,0,1,0,0,0,2,0,0],"10.1016/j.gie.2006.04.033"],[17258085,"Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies.","J Am Coll Cardiol",2007,"Gami et al.",0,[7,0],[9.17,5.29],14.06,9,8,7,[2,0,1,1,0,1,0,1,2,0,0,0,0,0,0,0],"10.1016/j.jacc.2006.09.032"],[17309916,"Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies.","Circulation",2007,"Briguori et al.",2,[8],[5.08],14.06,16,8,8,[3,3,3,0,0,1,0,0,2,1,0,0,0,0,0,0],"10.1161/CIRCULATIONAHA.106.687152"],[17329309,"Changes in causes of death in systemic sclerosis, 1972-2002.","Ann Rheum Dis",2007,"Steen et al.",5,[11,14],[11.58,6.77],14.06,9,8,7,[1,0,0,1,0,2,0,1,0,0,0,0,0,2,1,0],"10.1136/ard.2006.066068"],[17368275,"Safety considerations with fibrate therapy.","Am J Cardiol",2007,"Davidson et al.",6,[7,4,13],[12.16,1.0,0.0],14.06,14,8,8,[1,1,0,0,0,2,1,0,3,0,0,0,0,0,0,1],"10.1016/j.amjcard.2006.11.016"],[17374833,"Lymph node evaluation and survival after curative resection of colon cancer: systematic review.","J Natl Cancer Inst",2007,"Chang et al.",1,[1,4],[14.06,14.06],14.06,9,8,7,[0,2,1,0,0,0,1,0,0,0,0,3,0,1,1,0],"10.1093/jnci/djk092"],[17556697,"Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial.","Am J Clin Nutr",2007,"Lappe et al.",2,[1],[4.65],14.06,8,8,7,[2,1,0,1,0,0,2,1,0,0,0,0,0,1,0,0],"10.1093/ajcn/85.6.1586"],[17577016,"Primary treatment of Waldenström macroglobulinemia with dexamethasone, rituximab, and cyclophosphamide.","J Clin Oncol",2007,"Dimopoulos et al.",3,[0,1,10],[14.06,14.06,14.06],14.06,8,8,7,[0,0,2,1,0,0,1,0,0,0,0,2,0,1,0,1],"10.1200/JCO.2007.10.9926"],[17588223,"The effect of restorative proctocolectomy on sexual function, urinary function, fertility, pregnancy and delivery: a systematic review.","Dis Colon Rectum",2007,"Cornish et al.",1,[4],[14.06],14.06,8,8,7,[1,1,0,1,1,0,0,2,0,0,0,0,0,2,0,0],"10.1007/s10350-007-0240-7"],[17687149,"Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803.","J Clin Oncol",2007,"Saltz et al.",2,[1,4],[14.06,14.06],14.06,9,8,7,[2,1,3,0,0,0,1,0,0,0,0,1,0,1,0,0],"10.1200/JCO.2007.11.2144"],[17697140,"Bridging therapy in patients on long-term oral anticoagulants who require surgery: the Prospective Peri-operative Enoxaparin Cohort Trial (PROSPECT).","J Thromb Haemost",2007,"Dunn et al.",3,[0],[14.06],14.06,8,8,7,[1,1,2,0,0,0,0,0,1,1,0,2,0,0,0,0],"10.1111/j.1538-7836.2007.02729.x"],[17869634,"Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis.","Lancet",2007,"Stettler et al.",0,[0],[14.06],14.06,8,8,7,[1,2,2,1,0,0,1,0,1,0,0,0,0,0,0,0],"10.1016/S0140-6736(07)61444-5"],[17914061,"Updated research nosology for HIV-associated neurocognitive disorders.","Neurology",2007,"Antinori et al.",7,[2,9,12],[11.58,11.58,11.58],14.06,9,8,7,[1,2,0,2,0,0,2,0,0,1,0,0,0,0,1,0],"10.1212/01.WNL.0000287431.88658.8b"],[17959966,"Continuous airway access for the difficult extubation: the efficacy of the airway exchange catheter.","Anesth Analg",2007,"Mort",6,[3],[14.06],14.06,8,8,7,[0,1,2,0,0,0,0,2,1,0,0,1,0,1,0,0],"10.1213/01.ane.0000282826.68646.a1"],[17998460,"Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.","Circulation",2007,"Murphy et al.",5,[2],[0.0],14.06,8,8,7,[2,0,1,1,1,0,0,2,0,0,1,0,0,0,0,0],"10.1161/CIRCULATIONAHA.107.698977"],[18077795,"Hemorrhagic stroke in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels study.","Neurology",2008,"Goldstein et al.",2,[0,5],[14.06,9.77],14.06,10,8,7,[1,1,0,0,1,0,0,0,2,0,0,3,0,0,1,0],"10.1212/01.wnl.0000296277.63350.77"],[18166574,"Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas.","Pediatrics",2008,"Greer et al.",6,[12,14,17],[14.06,0.0,0.0],14.06,10,8,9,[1,2,0,0,1,1,2,0,0,0,1,0,0,0,0,0],"10.1542/peds.2007-3022"],[18236389,"Meta-analysis of risk for relapse to substance use after transplantation of the liver or other solid organs.","Liver Transpl",2008,"Dew et al.",0,[6],[1.0],14.06,9,8,7,[0,0,1,1,0,0,0,2,1,0,0,0,1,2,0,0],"10.1002/lt.21278"],[18250227,"The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases.","Blood",2008,"Kiladjian et al.",5,[0],[10.83],14.06,8,8,7,[0,0,0,1,0,1,2,0,1,1,2,0,0,0,0,0],"10.1182/blood-2007-11-125328"],[18419443,"Aerosolized liposomal amphotericin B for the prevention of invasive pulmonary aspergillosis during prolonged neutropenia: a randomized, placebo-controlled trial.","Clin Infect Dis",2008,"Rijnders et al.",2,[2,10,3],[12.16,4.04,0.0],14.06,10,8,7,[4,1,0,0,0,2,0,1,1,0,0,0,0,1,0,0],"10.1086/586739"],[18439766,"Impact of postoperative radiation therapy on survival in patients with complete resection and stage I, II, or IIIA non-small-cell lung cancer treated with adjuvant chemotherapy: the adjuvant Navelbine International Trialist Association (ANITA) Randomized Trial.","Int J Radiat Oncol Biol Phys",2008,"Douillard et al.",2,[1,3],[14.06,14.06],14.06,8,8,7,[0,1,2,1,2,0,0,0,0,0,0,1,1,0,0,0],"10.1016/j.ijrobp.2008.01.044"],[18480428,"Cluster analysis and clinical asthma phenotypes.","Am J Respir Crit Care Med",2008,"Haldar et al.",5,[12,3],[14.06,12.16],14.06,8,8,7,[0,0,1,0,2,1,2,0,0,1,0,0,1,0,0,0],"10.1164/rccm.200711-1754OC"],[18482589,"Random comparison of guaiac and immunochemical fecal occult blood tests for colorectal cancer in a screening population.","Gastroenterology",2008,"van Rossum et al.",2,[1,4],[14.06,14.06],14.06,9,8,7,[0,2,1,0,0,1,1,0,0,0,0,0,2,1,0,0],"10.1053/j.gastro.2008.03.040"],[18490378,"Is antibiotic prophylaxis in children with vesicoureteral reflux effective in preventing pyelonephritis and renal scars? A randomized, controlled trial.","Pediatrics",2008,"Pennesi et al.",2,[8],[14.06],14.06,9,8,7,[1,2,0,1,1,0,2,0,0,0,0,0,0,2,0,0],"10.1542/peds.2007-2652"],[18508782,"Sudden arrhythmic death syndrome: familial evaluation identifies inheritable heart disease in the majority of families.","Eur Heart J",2008,"Behr et al.",7,[0],[14.06],14.06,10,8,7,[0,0,1,0,3,1,0,0,0,0,1,0,0,1,2,0],"10.1093/eurheartj/ehn219"],[18564158,"The treatment of adolescent transsexuals: changing insights.","J Sex Med",2008,"Cohen-Kettenis et al.",7,[6],[2.69],14.06,8,8,7,[0,1,0,1,2,0,2,0,0,1,0,0,0,0,0,1],"10.1111/j.1743-6109.2008.00870.x"],[18596631,"Early intensive care unit mobility therapy in the treatment of acute respiratory failure.","Crit Care Med",2008,"Morris et al.",3,[3],[9.02],14.06,10,8,7,[0,0,2,2,1,0,0,1,0,1,0,0,0,1,0,0],"10.1097/CCM.0b013e318180b90e"],[18625622,"IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial.","Ann Rheum Dis",2008,"Emery et al.",2,[11],[14.06],14.06,8,8,7,[1,2,0,0,2,0,1,0,1,0,0,1,0,0,0,0],"10.1136/ard.2008.092932"],[18799443,"Prevalence of symptomatic pelvic floor disorders in US women.","JAMA",2008,"Nygaard et al.",7,[8,4,9],[10.16,6.77,4.04],14.06,8,8,7,[0,0,0,1,1,0,2,2,1,0,0,1,0,0,0,0],"10.1001/jama.300.11.1311"],[18838728,"Systematic review: D-dimer to predict recurrent disease after stopping anticoagulant therapy for unprovoked venous thromboembolism.","Ann Intern Med",2008,"Verhovsek et al.",1,[0],[14.06],14.06,8,8,7,[2,2,1,0,0,1,0,0,0,1,0,0,0,1,0,0],"10.7326/0003-4819-149-7-200810070-00008"],[18945961,"Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review.","Blood",2009,"Stasi et al.",1,[2,10],[7.47,4.04],14.06,8,8,7,[2,1,1,0,1,0,2,0,0,0,0,0,0,1,0,0],"10.1182/blood-2008-07-167155"],[18971951,"Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma.","Leukemia",2009,"Kyle et al.",6,[0,1,10],[14.06,14.06,14.06],14.06,8,8,7,[2,1,2,0,1,1,1,0,0,0,0,0,0,0,0,0],"10.1038/leu.2008.291"],[18975369,"Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial.","Arthritis Rheum",2008,"Schumacher et al.",2,[7,11,17],[14.06,14.06,14.06],14.06,9,8,7,[0,1,1,0,0,1,3,0,0,1,0,1,0,0,0,0],"10.1002/art.24209"],[19098912,"Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.","Nat Genet",2009,"Ligtenberg et al.",7,[1,4,17],[14.06,14.06,11.58],14.06,8,8,7,[0,1,2,0,2,0,0,1,1,0,0,0,0,0,1,0],"10.1038/ng.283"],[19101390,"Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial.","Lancet",2008,"Murphy et al.",2,[9,17],[9.77,2.69],14.06,9,8,8,[0,0,0,0,1,1,3,2,0,1,0,0,0,0,0,1],"10.1016/S0140-6736(08)61929-7"],[19106675,"Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis.","Ann Surg",2009,"Campos et al.",0,[4],[14.06],14.06,9,8,7,[0,2,1,0,0,0,0,2,0,2,1,0,0,0,1,0],"10.1097/SLA.0b013e31818e43ab"],[19152905,"Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a series of meta-analyses.","Gastrointest Endosc",2009,"Barkun et al.",0,[4],[14.06],14.06,8,8,7,[0,2,0,0,1,2,0,0,1,1,0,0,0,0,1,0],"10.1016/j.gie.2008.05.031"],[19160273,"Open versus laparoscopic (assisted) ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis.","Cochrane Database Syst Rev",2009,"Ahmed Ali et al.",0,[4,1,17],[14.06,1.0,0.0],14.06,9,8,8,[0,1,0,0,2,0,1,3,0,0,0,0,1,1,0,0],"10.1002/14651858.CD006267.pub2"],[19297346,"Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study.","Ann Rheum Dis",2010,"Jones et al.",2,[11],[14.06],14.06,8,8,7,[1,0,1,2,1,0,2,0,0,0,0,0,0,0,0,1],"10.1136/ard.2008.105197"],[19335706,"Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: a systematic review.","Int J Clin Pract",2009,"Jeannon et al.",1,[3,5,7],[6.84,6.84,9.02],14.06,9,8,7,[0,0,2,0,0,1,0,2,0,1,0,1,0,0,1,0],"10.1111/j.1742-1241.2008.01875.x"],[19357408,"Myocarditis.","N Engl J Med",2009,"Cooper",6,[0],[9.77],14.06,8,8,7,[0,0,2,0,1,2,0,0,1,0,0,0,1,0,1,0],"10.1056/NEJMra0800028"],[19465235,"Stress hyperglycaemia.","Lancet",2009,"Dungan et al.",6,[7],[14.06],14.06,9,8,8,[0,1,0,0,0,1,0,1,0,1,0,0,0,0,3,1],"10.1016/S0140-6736(09)60553-5"],[19572118,"The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study.","Intensive Care Med",2009,"Alberda et al.",5,[2,7],[6.2,5.29],14.06,8,8,7,[0,0,1,1,0,2,0,0,2,0,1,0,0,1,0,0],"10.1007/s00134-009-1567-4"],[19690526,"Complete Barrett's eradication endoscopic mucosal resection: an effective treatment modality for high-grade dysplasia and intramucosal carcinoma--an American single-center experience.","Am J Gastroenterol",2009,"Chennat et al.",5,[1,4],[10.26,14.06],14.06,8,8,7,[1,1,1,0,2,1,0,0,0,0,0,0,0,2,0,0],"10.1038/ajg.2009.465"],[19766646,"Long-term probability of and mortality from de novo malignancy after liver transplantation.","Gastroenterology",2009,"Watt et al.",5,[1],[1.9],14.06,8,8,7,[0,0,0,1,0,1,0,1,0,0,2,0,0,2,0,1],"10.1053/j.gastro.2009.08.070"],[19841328,"Clinically driven diagnostic antifungal approach in neutropenic patients: a prospective feasibility study.","J Clin Oncol",2010,"Girmenia et al.",5,[10,2,1],[10.16,14.06,8.47],14.06,8,8,7,[2,2,0,1,1,0,0,0,1,0,0,0,0,0,1,0],"10.1200/JCO.2009.21.8032"],[19864673,"Antibiotic prophylaxis and recurrent urinary tract infection in children.","N Engl J Med",2009,"Craig et al.",2,[8,2],[14.06,11.38],14.06,9,8,7,[1,2,0,0,2,0,2,0,0,0,0,0,0,1,0,1],"10.1056/NEJMoa0902295"],[19952143,"Abacavir-lamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy.","N Engl J Med",2009,"Sax et al.",2,[2,9,12],[14.06,14.06,14.06],14.06,13,8,7,[1,5,1,3,2,1,0,0,0,0,0,0,0,0,0,0],"10.1056/NEJMoa0906768"],[19998273,"Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates.","Cancer",2010,"Edwards et al.",7,[1,4],[14.06,14.06],14.06,11,8,8,[0,0,1,1,1,0,0,2,0,2,0,0,0,2,0,0],"10.1002/cncr.24760"],[20115947,"Infliximab therapy for patients with moderate to severe hidradenitis suppurativa: a randomized, double-blind, placebo-controlled crossover trial.","J Am Acad Dermatol",2010,"Grant et al.",2,[2,14],[14.06,14.06],14.06,8,8,7,[0,1,0,0,1,0,0,0,1,0,0,0,0,1,3,1],"10.1016/j.jaad.2009.06.050"],[20137879,"Endovascular aortic repair versus open surgical repair for descending thoracic aortic disease a systematic review and meta-analysis of comparative studies.","J Am Coll Cardiol",2010,"Cheng et al.",0,[0],[14.06],14.06,8,8,7,[0,2,0,2,0,0,1,0,0,0,1,0,1,1,0,0],"10.1016/j.jacc.2009.11.047"],[20159292,"Comparative effectiveness of MRI in breast cancer (COMICE) trial: a randomised controlled trial.","Lancet",2010,"Turnbull et al.",2,[1],[14.06],14.06,9,8,7,[0,1,0,0,1,4,1,0,0,0,0,0,1,1,0,0],"10.1016/S0140-6736(09)62070-5"],[20180235,"Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis.","World J Gastroenterol",2010,"Mueller et al.",7,[4],[14.06],14.06,8,8,7,[0,1,0,1,1,0,2,0,0,0,0,1,0,2,0,0],"10.3748/wjg.v16.i8.966"],[20226452,"Postpolypectomy bleeding in patients undergoing colonoscopy on uninterrupted clopidogrel therapy.","Gastrointest Endosc",2010,"Singh et al.",5,[4],[14.06],14.06,9,8,7,[2,1,0,1,1,2,0,0,0,0,0,0,0,1,0,0],"10.1016/j.gie.2009.11.022"],[20385793,"Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials.","Blood",2010,"Grimwade et al.",3,[1,10],[14.06,14.06],14.06,8,8,7,[0,0,0,0,0,1,1,0,1,0,1,0,2,0,0,2],"10.1182/blood-2009-11-254441"],[20420948,"Role of the serrated pathway in colorectal cancer pathogenesis.","Gastroenterology",2010,"Leggett et al.",6,[1,4],[11.58,14.06],14.06,9,8,7,[0,2,0,1,2,0,1,0,1,0,2,0,0,0,0,0],"10.1053/j.gastro.2009.12.066"],[20453069,"Factors at admission associated with bleeding risk in medical patients: findings from the IMPROVE investigators.","Chest",2011,"Decousus et al.",2,[0],[6.77],14.06,8,8,7,[0,1,0,0,0,0,0,1,0,2,1,0,0,0,2,1],"10.1378/chest.09-3081"],[20512990,"Intrahepatic peripheral cholangiocarcinoma in cirrhosis patients may display a vascular pattern similar to hepatocellular carcinoma on contrast-enhanced ultrasound.","Hepatology",2010,"Vilana et al.",7,[4,1],[14.06,11.58],14.06,9,8,7,[0,0,3,0,0,1,0,0,0,1,1,0,0,0,1,1],"10.1002/hep.23600"],[20564351,"Outcome of sustained virological responders with histologically advanced chronic hepatitis C.","Hepatology",2010,"Morgan et al.",2,[4,2],[14.06,12.16],14.06,9,8,8,[1,1,0,0,0,1,1,0,2,2,0,0,0,0,0,0],"10.1002/hep.23744"],[20598077,"PRODIGE: a randomized placebo-controlled trial of dalteparin low-molecular-weight heparin thromboprophylaxis in patients with newly diagnosed malignant glioma.","J Thromb Haemost",2010,"Perry et al.",2,[1,5],[14.06,3.74],14.06,9,8,7,[0,0,2,2,0,0,1,0,0,1,2,0,0,1,0,0],"10.1111/j.1538-7836.2010.03973.x"],[20841605,"Long-term absolute risk of cervical intraepithelial neoplasia grade 3 or worse following human papillomavirus infection: role of persistence.","J Natl Cancer Inst",2010,"Kjær et al.",5,[9,1,2],[14.06,11.58,6.77],14.06,9,8,8,[0,2,2,1,0,1,0,0,0,0,0,0,1,0,1,0],"10.1093/jnci/djq356"],[21060031,"Multicenter, randomized, cross-over clinical trial of venlafaxine versus gabapentin for the management of hot flashes in breast cancer survivors.","J Clin Oncol",2010,"Bordeleau et al.",2,[1],[10.26],14.06,11,8,7,[0,0,0,2,1,1,2,0,0,0,1,0,0,2,0,0],"10.1200/JCO.2010.29.9230"],[21410393,"Efficacy and safety of sirolimus in lymphangioleiomyomatosis.","N Engl J Med",2011,"McCormack et al.",2,[1,10],[11.38,4.65],14.06,9,8,8,[0,3,1,0,0,2,0,0,1,0,0,0,1,0,1,0],"10.1056/NEJMoa1100391"],[21415052,"The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study.","Ann Rheum Dis",2011,"Klarenbeek et al.",2,[11],[14.06],14.06,9,8,7,[0,1,1,3,1,0,0,2,0,1,0,0,0,0,0,0],"10.1136/ard.2010.141234"],[21482846,"Opioid dose and drug-related mortality in patients with nonmalignant pain.","Arch Intern Med",2011,"Gomes et al.",5,[6],[9.77],14.06,10,8,7,[0,0,0,2,1,2,2,0,0,0,1,1,0,0,0,0],"10.1001/archinternmed.2011.117"],[21484965,"Long-term infliximab maintenance therapy for ulcerative colitis: the ACT-1 and -2 extension studies.","Inflamm Bowel Dis",2012,"Reinisch et al.",2,[4],[14.06],14.06,8,8,7,[0,0,1,0,3,1,1,1,1,0,0,0,0,0,0,0],"10.1002/ibd.21697"],[21629249,"End-of-study safety, immunogenicity, and efficacy of quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine in adult women 24-45 years of age.","Br J Cancer",2011,"Castellsagué et al.",7,[9,1,7],[9.77,7.97,1.0],14.06,9,8,7,[0,2,1,0,0,1,0,0,3,0,1,0,0,0,0,1],"10.1038/bjc.2011.185"],[21793028,"Cancer surveillance in patients with primary sclerosing cholangitis.","Hepatology",2011,"Razumilava et al.",6,[4,1],[14.06,3.74],14.06,8,8,7,[0,0,0,1,2,0,2,0,0,1,0,1,0,0,0,1],"10.1002/hep.24570"],[21896934,"Impact of resistance training on blood pressure and other cardiovascular risk factors: a meta-analysis of randomized, controlled trials.","Hypertension",2011,"Cornelissen et al.",0,[0],[14.06],14.06,16,8,9,[0,1,2,0,0,1,0,0,2,0,0,0,1,0,0,1],"10.1161/HYPERTENSIONAHA.111.177071"],[22010128,"Maternal exposure to angiotensin converting enzyme inhibitors in the first trimester and risk of malformations in offspring: a retrospective cohort study.","BMJ",2011,"Li et al.",5,[17],[0.0],14.06,8,8,7,[0,3,1,0,0,0,0,1,1,1,0,1,0,0,0,0],"10.1136/bmj.d5931"],[22119930,"Granulocyte colony-stimulating factor mobilizes CD34(+) cells and improves survival of patients with acute-on-chronic liver failure.","Gastroenterology",2012,"Garg et al.",2,[4],[14.06],14.06,8,8,7,[0,0,0,0,0,2,0,1,0,0,1,0,2,1,1,0],"10.1053/j.gastro.2011.11.027"],[22142484,"Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection.","J Gastroenterol Hepatol",2012,"Nakadoi et al.",7,[1,4],[14.06,14.06],14.06,8,8,7,[0,0,0,1,1,0,1,0,1,0,0,0,0,1,3,0],"10.1111/j.1440-1746.2011.07041.x"],[22198786,"β-Glucan antigenemia assay for the diagnosis of invasive fungal infections in patients with hematological malignancies: a systematic review and meta-analysis of cohort studies from the Third European Conference on Infections in Leukemia (ECIL-3).","Clin Infect Dis",2012,"Lamoth et al.",0,[2,1,10],[14.06,6.2,6.2],14.06,8,8,7,[0,2,0,1,0,2,0,0,1,0,0,0,1,0,1,0],"10.1093/cid/cir897"],[22239517,"Virologic factors associated with failure to passive-active immunoprophylaxis in infants born to HBsAg-positive mothers.","J Viral Hepat",2012,"Zou et al.",7,[2,4,9],[12.63,12.16,4.65],14.06,9,8,7,[0,1,0,0,0,3,2,0,1,0,0,1,1,0,0,0],"10.1111/j.1365-2893.2011.01492.x"],[22271738,"A systematic review of the effectiveness of interventions in the management of infection in the diabetic foot.","Diabetes Metab Res Rev",2012,"Peters et al.",1,[0,14,7],[11.58,12.16,9.77],14.06,8,8,7,[0,0,1,1,0,2,0,0,1,0,0,0,0,2,1,0],"10.1002/dmrr.2247"],[22344983,"Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease.","Inflamm Bowel Dis",2012,"D'Haens et al.",7,[4],[14.06],14.06,8,8,7,[0,0,1,0,0,0,1,3,1,1,1,0,0,0,0,0],"10.1002/ibd.22917"],[22393128,"Low-dose prednisone inclusion in a methotrexate-based, tight control strategy for early rheumatoid arthritis: a randomized trial.","Ann Intern Med",2012,"Bakker et al.",2,[11],[14.06],14.06,9,8,7,[0,1,0,2,1,2,0,1,0,0,0,0,0,0,1,0],"10.7326/0003-4819-156-5-201203060-00004"],[22436955,"Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.","JAMA",2012,"Jakob et al.",2,[5,6],[9.77,9.77],14.06,11,8,7,[0,0,2,0,1,0,0,1,0,0,0,2,0,1,2,0],"10.1001/jama.2012.304"],[22544366,"Meta-analysis identifies six new susceptibility loci for atrial fibrillation.","Nat Genet",2012,"Ellinor et al.",0,[0],[14.06],14.06,15,8,7,[0,1,0,2,0,4,1,1,0,1,0,0,0,0,0,0],"10.1038/ng.2261"],[22610925,"Challenging recommended oral and intravenous voriconazole doses for improved efficacy and safety: population pharmacokinetics-based analysis of adult patients with invasive fungal infections.","Clin Infect Dis",2012,"Pascual et al.",7,[2],[14.06],14.06,9,8,7,[0,0,0,3,0,2,0,1,1,0,0,0,0,1,1,0],"10.1093/cid/cis437"],[22744937,"Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab.","Circ Cardiovasc Imaging",2012,"Sawaya et al.",5,[0,1],[13.27,9.77],14.06,8,8,7,[0,0,2,0,0,2,1,0,0,1,0,1,0,0,1,0],"10.1161/CIRCIMAGING.112.973321"],[22752865,"Treatment of first recurrence of Clostridium difficile infection: fidaxomicin versus vancomycin.","Clin Infect Dis",2012,"Cornely et al.",2,[2],[11.58],14.06,9,8,7,[0,0,0,1,1,0,0,1,0,0,3,0,0,1,1,0],"10.1093/cid/cis462"],[22972105,"Black cohosh (Cimicifuga spp.) for menopausal symptoms.","Cochrane Database Syst Rev",2012,"Leach et al.",0,[9,7],[5.78,1.9],14.06,9,8,7,[0,0,1,0,2,0,1,0,0,0,2,0,0,0,1,1],"10.1002/14651858.CD007244.pub2"],[23047045,"Zoledronic acid (zoledronate) for postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study): final 60-month results.","Ann Oncol",2013,"Coleman et al.",3,[1],[12.16],14.06,8,8,7,[0,0,0,1,1,2,2,0,1,0,0,0,0,0,1,0],"10.1093/annonc/mds277"],[23048011,"Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial.","BMJ",2012,"Schierbeck et al.",2,[0,1],[12.16,5.08],14.06,10,8,7,[0,0,0,0,1,0,2,1,0,0,3,0,0,1,1,0],"10.1136/bmj.e6409"],[23091106,"Risks of less common cancers in proven mutation carriers with lynch syndrome.","J Clin Oncol",2012,"Engel et al.",5,[1,4,7],[14.06,13.27,9.48],14.06,13,8,10,[0,0,2,1,3,1,0,0,2,0,0,0,0,1,0,0],"10.1200/JCO.2012.43.2278"],[23213105,"A European Organisation for Research and Treatment of Cancer phase III trial of adjuvant whole-brain radiotherapy versus observation in patients with one to three brain metastases from solid tumors after surgical resection or radiosurgery: quality-of-life results.","J Clin Oncol",2013,"Soffietti et al.",2,[1,5],[14.06,14.06],14.06,8,8,7,[0,0,0,1,1,1,1,2,0,0,0,2,0,0,0,0],"10.1200/JCO.2011.41.0639"],[23339638,"High-frequency oscillation for acute respiratory distress syndrome.","N Engl J Med",2013,"Young et al.",2,[3],[8.47],14.06,11,8,8,[0,0,0,0,1,0,3,1,1,2,0,1,0,0,0,0],"10.1056/NEJMoa1215716"],[23357492,"Efficacy, safety, and long-term results of endoscopic treatment for early stage adenocarcinoma of the esophagus with low-risk sm1 invasion.","Clin Gastroenterol Hepatol",2013,"Manner et al.",7,[1,4],[12.16,14.06],14.06,9,8,7,[0,0,0,0,1,1,0,0,1,0,0,2,1,3,0,0],"10.1016/j.cgh.2012.12.040"],[23393084,"Increased left ventricular trabeculation in highly trained athletes: do we need more stringent criteria for the diagnosis of left ventricular non-compaction in athletes?","Heart",2013,"Gati et al.",5,[0],[14.06],14.06,9,8,7,[0,0,0,0,0,0,1,1,3,0,1,0,0,1,1,0],"10.1136/heartjnl-2012-303418"],[23583250,"Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome.","J Am Coll Cardiol",2013,"Cullen et al.",2,[0],[14.06],14.06,11,8,7,[0,0,0,0,3,2,0,0,1,0,0,1,1,0,1,0],"10.1016/j.jacc.2013.02.078"],[23669885,"Factors affecting quality of anticoagulation control among patients with atrial fibrillation on warfarin: the SAMe-TT₂R₂ score.","Chest",2013,"Apostolakis et al.",2,[0,5],[14.06,4.65],14.06,14,8,7,[0,0,0,0,1,2,2,2,0,0,0,1,0,1,0,0],"10.1378/chest.13-0054"],[23697825,"Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis.","Lancet",2013,"Chopra et al.",0,[0],[8.47],14.06,8,8,7,[0,0,0,1,1,0,0,1,0,1,0,0,0,1,3,0],"10.1016/S0140-6736(13)60592-9"],[23782973,"Heparin thromboprophylaxis in medical-surgical critically ill patients: a systematic review and meta-analysis of randomized trials.","Crit Care Med",2013,"Alhazzani et al.",0,[0],[7.47],14.06,10,8,8,[0,0,0,0,0,1,1,2,0,3,0,0,1,1,0,0],"10.1097/CCM.0b013e31828cf104"],[23878167,"Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment: a randomised, controlled trial.","Gut",2014,"Steenholdt et al.",2,[4],[14.06],14.06,10,8,7,[0,0,0,1,0,0,1,0,1,2,0,0,2,3,0,0],"10.1136/gutjnl-2013-305279"],[23942868,"Effect of certolizumab pegol on signs and 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al.",5,[1,4],[13.27,14.06],14.06,9,8,7,[0,0,0,0,0,1,1,0,0,1,0,0,2,2,2,0],"10.1055/s-0033-1344760"],[24240112,"Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas.","Clin Cancer Res",2014,"Pennington et al.",7,[1,9,7],[14.06,14.06,14.06],14.06,8,8,7,[0,0,0,0,0,0,1,1,1,2,0,0,0,2,1,0],"10.1158/1078-0432.CCR-13-2287"],[24331909,"Parameters for successful nonoperative management of traumatic aortic injury.","J Thorac Cardiovasc Surg",2014,"Rabin et al.",5,[13,0],[4.65,12.16],14.06,10,8,7,[0,0,0,0,0,0,0,0,0,2,0,1,2,1,1,2],"10.1016/j.jtcvs.2013.08.053"],[24382410,"A randomized controlled trial of catheter ablation versus medical treatment of atrial fibrillation in heart failure (the CAMTAF trial).","Circ Arrhythm Electrophysiol",2014,"Hunter et al.",2,[0],[14.06],14.06,16,8,7,[0,1,0,0,0,1,1,2,0,0,0,2,0,4,0,0],"10.1161/CIRCEP.113.000806"],[24419479,"Association between thiopurine use and nonmelanoma skin cancers in patients with inflammatory bowel disease: a meta-analysis.","Am J Gastroenterol",2014,"Ariyaratnam et al.",0,[4,1,14],[14.06,1.35,1.35],14.06,9,8,7,[0,0,0,1,1,0,3,1,1,0,0,0,0,0,2,0],"10.1038/ajg.2013.451"],[24470482,"Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients taking an oral anticoagulant: a nationwide cohort study.","Circulation",2014,"Lamberts et al.",5,[0],[14.06],14.06,11,8,7,[0,0,0,0,1,2,1,2,0,0,0,1,1,0,0,0],"10.1161/CIRCULATIONAHA.113.004834"],[24556041,"Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial.","Lancet Oncol",2014,"Conroy et al.",2,[1,4],[14.06,14.06],14.06,10,8,7,[0,0,0,0,2,1,0,0,0,0,0,3,1,0,2,1],"10.1016/S1470-2045(14)70028-2"],[24633881,"Temporal relationship between subclinical atrial fibrillation and embolic events.","Circulation",2014,"Brambatti et al.",3,[0,5],[14.06,4.65],14.06,15,8,8,[0,0,0,1,0,3,1,2,0,0,0,0,0,2,1,0],"10.1161/CIRCULATIONAHA.113.007825"],[24723079,"Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis.","Ann Intern Med",2014,"Chowdhury et al.",0,[0],[12.16],14.06,8,8,7,[0,0,0,0,1,3,0,1,1,1,0,0,1,0,0,0],"10.7326/M13-1788"],[24783248,"Impact of rapid on-site evaluation on the adequacy of endoscopic-ultrasound guided fine-needle aspiration of solid pancreatic lesions: a systematic review and meta-analysis.","J Gastroenterol Hepatol",2014,"Matynia et al.",0,[4],[14.06],14.06,9,8,8,[0,0,0,0,0,1,1,0,0,0,1,0,2,2,1,0],"10.1111/jgh.12431"],[24812292,"Higher disease activity leads to more structural damage in the spine in ankylosing spondylitis: 12-year longitudinal data from the OASIS cohort.","Ann Rheum Dis",2014,"Ramiro et al.",5,[11,13],[14.06,14.06],14.06,8,8,7,[0,0,0,0,0,1,2,2,1,0,1,0,1,0,0,0],"10.1136/annrheumdis-2014-205178"],[24842305,"Prognosis of acute severe autoimmune hepatitis (AS-AIH): the role of corticosteroids in modifying outcome.","J Hepatol",2014,"Yeoman et al.",5,[4,2,5],[14.06,0.0,0.0],14.06,9,8,7,[0,0,0,0,2,0,1,0,0,1,0,0,1,1,3,0],"10.1016/j.jhep.2014.05.021"],[24890256,"Cesarean scar pregnancy is a precursor of morbidly adherent placenta.","Ultrasound Obstet Gynecol",2014,"Timor-Tritsch et al.",6,[9],[14.06],14.06,9,8,7,[0,0,0,0,0,1,1,1,1,3,1,0,0,0,0,0],"10.1002/uog.13426"],[24910231,"Prevention and management of type 2 diabetes: dietary components and nutritional strategies.","Lancet",2014,"Ley et al.",6,[7],[14.06],14.06,8,8,7,[0,0,0,0,0,0,0,1,1,2,2,1,0,1,0,0],"10.1016/S0140-6736(14)60613-9"],[24942631,"Efficacy and cost of video-assisted thoracoscopic partial pleurectomy versus talc pleurodesis in patients with malignant pleural mesothelioma (MesoVATS): an open-label, randomised, controlled trial.","Lancet",2014,"Rintoul et al.",2,[1,3],[14.06,14.06],14.06,9,8,7,[0,0,0,0,1,1,0,4,0,1,1,1,0,0,0,0],"10.1016/S0140-6736(14)60418-9"],[25178701,"Covert hepatic encephalopathy is independently associated with poor survival and increased risk of hospitalization.","Am J Gastroenterol",2014,"Patidar et al.",5,[4,5,7],[14.06,4.65,4.65],14.06,8,8,7,[0,0,0,0,1,0,0,0,0,1,0,1,0,1,3,1],"10.1038/ajg.2014.264"],[25387589,"Platelet transfusion: a systematic review of the clinical evidence.","Transfusion",2015,"Kumar et al.",1,[10],[6.77],14.06,8,8,7,[0,0,0,0,1,1,2,2,1,0,0,0,0,0,1,0],"10.1111/trf.12943"],[25405392,"Atenolol versus losartan in children and young adults with Marfan's syndrome.","N Engl J Med",2014,"Lacro et al.",2,[0,17,11],[14.06,1.35,0.0],14.06,12,8,8,[0,0,0,0,0,0,2,0,1,0,0,2,2,1,1,0],"10.1056/NEJMoa1404731"],[25440678,"Comparative effectiveness of biliary brush cytology and intraductal biopsy for detection of malignant biliary strictures: a systematic review and meta-analysis.","Gastrointest Endosc",2015,"Navaneethan et al.",0,[4,1,7],[14.06,7.75,0.0],14.06,9,8,7,[0,0,0,0,0,0,1,0,0,0,1,0,3,2,1,1],"10.1016/j.gie.2014.09.017"],[25480101,"Quality indicators for EGD.","Gastrointest Endosc",2015,"Park et al.",6,[4],[12.32],14.06,10,10,6,[0,0,0,0,0,0,1,0,0,0,1,3,1,0,3,1],"10.1016/j.gie.2014.07.057"],[25629741,"Ruxolitinib versus standard therapy for the treatment of polycythemia vera.","N Engl J Med",2015,"Vannucchi et al.",2,[10,1],[11.58,3.25],14.06,8,8,7,[0,0,0,0,0,1,1,1,3,0,0,1,0,0,1,0],"10.1056/NEJMoa1409002"],[25701104,"The effectiveness of screening history, physical exam, and ECG to detect potentially lethal cardiac disorders in athletes: a systematic review/meta-analysis.","J Electrocardiol",2015,"Harmon et al.",0,[0],[14.06],14.06,9,8,7,[0,0,0,0,0,1,1,0,0,1,0,0,0,1,2,2],"10.1016/j.jelectrocard.2015.02.001"],[26026936,"Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled 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The female athlete triad.","Med Sci Sports Exerc",2007,"Nattiv et al.",7,[6],[9.77],13.38,8,8,7,[2,0,0,1,0,0,2,0,0,2,0,0,0,0,0,1],"10.1249/mss.0b013e318149f111"],[17975326,"Prevalence of dementia in the United States: the aging, demographics, and memory study.","Neuroepidemiology",2007,"Plassman et al.",5,[5,6],[10.16,9.17],13.38,8,8,7,[1,2,0,3,0,0,0,1,0,0,0,1,0,0,0,0],"10.1159/000109998"],[20370912,"The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.","Arthritis Res Ther",2010,"Becker et al.",2,[7,11,17],[10.86,10.86,10.86],13.38,8,8,7,[0,2,1,1,0,1,3,0,0,0,0,0,0,0,0,0],"10.1186/ar2978"],[20460624,"Diagnosing and managing common food allergies: a systematic review.","JAMA",2010,"Chafen et al.",1,[12],[10.86],13.38,8,8,7,[0,0,1,4,1,1,1,0,0,0,0,0,0,0,0,0],"10.1001/jama.2010.582"],[21800283,"Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008.","Arthritis Rheum",2011,"Zhu et al.",7,[11,7,17],[11.58,9.17,9.17],13.38,8,8,7,[0,2,2,0,0,0,2,0,0,0,0,1,1,0,0,0],"10.1002/art.30520"],[22206777,"Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial.","J Allergy Clin Immunol",2012,"Spergel et al.",2,[4,10,12],[13.38,13.38,13.38],13.38,8,8,7,[0,0,1,1,0,0,0,0,0,1,0,0,0,3,2,0],"10.1016/j.jaci.2011.11.044"],[23846772,"Fluoride varnishes for preventing dental caries in children and adolescents.","Cochrane Database Syst Rev",2013,"Marinho et al.",0,[16],[11.58],13.38,8,8,7,[0,0,0,1,0,0,2,0,1,0,0,0,0,0,1,3],"10.1002/14651858.CD002279.pub2"],[24825644,"Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.","JAMA",2014,"Jonas et al.",0,[6],[11.58],13.38,8,8,7,[0,0,0,0,0,1,0,2,1,0,0,0,1,3,0,0],"10.1001/jama.2014.3628"],[25957714,"Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis.","Lancet Oncol",2015,"Blanchard et al.",0,[1,16],[13.38,11.58],13.38,9,8,7,[0,0,0,0,0,1,0,0,0,2,3,2,0,0,0,1],"10.1016/S1470-2045(15)70126-9"],[31742630,"Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping With Death or Severe Intraventricular Hemorrhage Among Preterm Infants.","JAMA",2019,"Katheria et al.",2,[17,0,5],[12.63,6.84,1.0],13.38,9,8,7,[0,0,0,0,0,0,0,0,0,1,1,0,1,0,4,2],"10.1001/jama.2019.16004"],[17440145,"Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials.","JAMA",2007,"Bridge et al.",0,[6],[8.54],13.28,8,8,6,[0,0,0,0,1,1,1,0,0,1,1,0,1,0,0,2],"10.1001/jama.297.15.1683"],[18374841,"Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial.","Lancet",2008,"Kahn et al.",2,[6],[13.28],13.28,9,8,6,[1,2,1,0,0,2,1,0,0,1,0,0,1,0,0,0],"10.1016/S0140-6736(08)60486-9"],[18662829,"A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema.","Ophthalmology",2008,"Diabetic Retinopathy Clinical Research N",2,[15,0,7],[13.28,12.16,12.16],13.28,9,8,6,[1,1,0,2,0,1,2,0,0,1,0,1,0,0,0,0],"10.1016/j.ophtha.2008.06.015"],[2646336,"Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up.","J Dermatol Surg Oncol",1989,"Rowe et al.",6,[1,14],[13.27,13.27],13.27,7,7,7,[0,0,0,1,1,1,0,1,0,1,0,0,0,2,0,0],"10.1111/j.1524-4725.1989.tb03166.x"],[3314832,"Does colchicine work? The results of the first controlled study in acute gout.","Aust N Z J Med",1987,"Ahern et al.",2,[11,7,17],[13.27,10.83,10.83],13.27,7,7,7,[1,1,1,0,0,1,2,0,0,0,0,1,0,0,0,0],"10.1111/j.1445-5994.1987.tb01232.x"],[3921901,"Facial nerve grading system.","Otolaryngol Head Neck Surg",1985,"House et al.",7,[5,16],[13.27,13.27],13.27,7,7,7,[0,1,1,1,0,0,1,0,0,2,0,0,0,1,0,0],"10.1177/019459988509300202"],[7993409,"Mortality in sickle cell disease. Life expectancy and risk factors for early death.","N Engl J Med",1994,"Platt et al.",7,[10,17],[10.83,10.83],13.27,7,7,7,[0,0,0,1,2,0,0,1,1,1,0,1,0,0,0,0],"10.1056/NEJM199406093302303"],[11407694,"A randomized, controlled trial of methotrexate versus placebo in early diffuse scleroderma.","Arthritis Rheum",2001,"Pope et al.",2,[14,11],[13.27,10.83],13.27,7,7,7,[0,1,1,0,0,1,2,1,0,0,0,0,0,1,0,0],"10.1002/1529-0131(200106)44:6<1351::AID-ART227>3.0.CO;2-I"],[11669169,"A comparison of cyclosporine, sulfasalazine, and symptomatic therapy in the treatment of psoriatic arthritis.","J Rheumatol",2001,"Salvarani et al.",2,[14,11,13],[13.27,10.83,10.83],13.27,7,7,7,[1,2,1,0,0,0,1,1,0,0,1,0,0,0,0,0],""],[12970230,"Coronary events after arterial switch operation for transposition of the great arteries.","Circulation",2003,"Legendre et al.",5,[0,17],[13.27,13.27],13.27,14,7,9,[0,0,0,0,0,1,1,0,1,2,0,2,0,0,0,1],"10.1161/01.cir.0000087902.67220.2b"],[15097956,"Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase III, randomized, vehicle-controlled studies.","J Am Acad Dermatol",2004,"Geisse et al.",2,[1,14],[13.27,13.27],13.27,7,7,7,[0,0,0,1,1,1,0,1,0,1,0,0,0,2,0,0],"10.1016/j.jaad.2003.11.066"],[15753237,"The lifetime risk of suicide in schizophrenia: a reexamination.","Arch Gen Psychiatry",2005,"Palmer et al.",0,[6],[9.02],13.27,8,7,7,[1,2,0,0,1,1,0,0,0,2,1,0,0,0,0,0],"10.1001/archpsyc.62.3.247"],[15860670,"MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients.","Blood",2005,"Wood et al.",5,[17,10],[13.27,9.02],13.27,7,7,7,[0,0,0,0,1,0,0,0,0,1,0,2,1,1,0,1],"10.1182/blood-2004-10-3982"],[16337461,"Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo.","J Allergy Clin Immunol",2005,"Meltzer et al.",2,[3,16,2],[13.27,13.27,11.38],13.27,8,7,7,[0,2,2,1,1,0,0,1,0,0,0,0,0,0,1,0],"10.1016/j.jaci.2005.08.044"],[16670409,"Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial.","JAMA",2006,"Anton et al.",2,[6],[9.02],13.27,7,7,7,[0,2,1,0,0,0,0,0,0,1,0,1,0,1,0,1],"10.1001/jama.295.17.2003"],[17265483,"Adalimumab for long-term treatment of psoriatic arthritis: forty-eight week data from the adalimumab effectiveness in psoriatic arthritis trial.","Arthritis Rheum",2007,"Gladman et al.",2,[14,11,13],[13.27,9.02,9.02],13.27,8,7,7,[1,2,1,0,1,0,0,1,2,0,0,0,0,0,0,0],"10.1002/art.22379"],[17919140,"Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction.","Allergy",2007,"Staden et al.",2,[12],[13.27],13.27,8,7,8,[2,2,0,1,1,0,1,1,0,0,0,0,0,0,0,0],"10.1111/j.1398-9995.2007.01501.x"],[18805335,"Management of asthma based on exhaled nitric oxide in addition to 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randomized clinical trial comparing methotrexate to cyclophosphamide for remission induction in early systemic antineutrophil cytoplasmic antibody-associated vasculitis.","Arthritis Rheum",2012,"Faurschou et al.",2,[0,11,14],[13.27,13.27,13.27],13.27,7,7,7,[0,0,0,0,1,1,0,0,0,1,0,0,1,1,2,0],"10.1002/art.34547"],[23098865,"Initiation of allopurinol at first medical contact for acute attacks of gout: a randomized clinical trial.","Am J Med",2012,"Taylor et al.",2,[7,11,17],[10.83,10.83,10.83],13.27,8,7,7,[0,0,0,0,0,1,2,0,0,1,0,1,1,1,0,0],"10.1016/j.amjmed.2012.05.025"],[23185525,"Omeprazole blocks STAT6 binding to the eotaxin-3 promoter in eosinophilic esophagitis cells.","PLoS One",2012,"Zhang et al.",7,[4,10,12],[13.27,13.27,13.27],13.27,7,7,7,[0,0,0,1,0,1,0,1,0,1,0,0,0,2,1,0],"10.1371/journal.pone.0050037"],[23239839,"Cardiovascular outcomes after the arterial switch operation for D-transposition of the great arteries.","Circulation",2013,"Khairy et al.",5,[0,17],[13.27,10.83],13.27,12,7,8,[0,0,0,1,0,0,1,0,2,1,0,1,0,1,0,0],"10.1161/CIRCULATIONAHA.112.135046"],[23902481,"Efficacy of remission-induction regimens for ANCA-associated vasculitis.","N Engl J Med",2013,"Specks et al.",2,[0,11,14],[13.27,13.27,13.27],13.27,8,7,7,[0,0,0,0,1,0,0,0,1,1,1,0,0,2,2,0],"10.1056/NEJMoa1213277"],[25692915,"Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema.","N Engl J Med",2015,"Wells et al.",2,[15,7,0],[8.47,13.27,10.83],13.27,7,7,7,[0,0,0,0,1,2,1,1,1,1,0,0,0,0,0,0],"10.1056/NEJMoa1414264"],[26480031,"Sentinel lymph node biopsy in Merkel cell carcinoma: a 15-year institutional experience and statistical analysis of 721 reported cases.","Br J Dermatol",2016,"Gunaratne et al.",5,[1,14,2],[13.27,13.27,11.38],13.27,8,7,7,[0,0,0,0,0,0,0,1,1,0,0,2,1,1,2,0],"10.1111/bjd.14240"],[27245173,"Adjuvant Radiation Therapy and Chemotherapy in Merkel Cell Carcinoma: Survival Analyses of 6908 Cases From the National Cancer Data Base.","J Natl 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initiation of antiretroviral therapy: a prospective cohort analysis.","Lancet",2010,"Donnell et al.",5,[2,9,12],[12.95,12.95,12.95],12.95,9,8,6,[0,2,2,2,1,1,0,0,0,0,0,1,0,0,0,0],"10.1016/S0140-6736(10)60705-2"],[21196094,"Effective dose range for dental cone beam computed tomography scanners.","Eur J Radiol",2012,"Pauwels et al.",7,[13,15],[1.0,1.0],12.95,8,8,6,[0,3,1,1,1,0,0,0,0,0,1,0,1,0,0,0],"10.1016/j.ejrad.2010.11.028"],[24944314,"Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010.","Circulation",2014,"Marelli et al.",7,[0,17],[12.95,12.95],12.95,10,8,6,[0,0,0,0,0,1,0,0,0,2,0,1,0,1,1,2],"10.1161/CIRCULATIONAHA.113.008396"],[17466703,"The long-term outcome in surviving infants with Apgar zero at 10 minutes: a systematic review of the literature and hospital-based cohort.","Am J Obstet Gynecol",2007,"Harrington et al.",1,[0,17],[12.9,11.58],12.9,11,9,6,[0,0,0,0,3,0,1,0,0,0,1,0,0,0,3,1],"10.1016/j.ajog.2006.10.877"],[22198423,"Early initiation 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triamcinolone plus prompt laser for diabetic macular edema.","Ophthalmology",2010,"Elman et al.",2,[15,7,0],[10.26,12.65,10.26],12.65,8,7,6,[1,1,0,2,1,0,1,0,1,1,0,0,0,0,0,0],"10.1016/j.ophtha.2010.02.031"],[20726724,"Radiation cataract risk in interventional cardiology personnel.","Radiat Res",2010,"Vano et al.",7,[13,15],[7.97,1.0],12.65,8,7,6,[0,1,1,1,1,0,0,1,0,0,1,0,0,1,0,0],"10.1667/RR2207.1"],[24809629,"Estimating per-act HIV transmission risk: a systematic review.","AIDS",2014,"Patel et al.",1,[2,9,12],[12.65,12.65,10.26],12.65,7,7,6,[0,0,0,0,1,1,1,0,1,0,1,0,1,0,1,0],"10.1097/QAD.0000000000000298"],[25282564,"Application of moisturizer to neonates prevents development of atopic dermatitis.","J Allergy Clin Immunol",2014,"Horimukai et al.",2,[12,14,17],[10.68,10.26,8.37],12.65,9,7,6,[0,0,0,0,0,1,0,1,1,1,0,2,0,0,2,1],"10.1016/j.jaci.2014.07.060"],[27939035,"Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double-blind, 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inadequate effect of methotrexate therapy.","Acta Derm Venereol",2008,"Zachariae et al.",2,[14],[12.63],12.63,9,7,8,[0,1,1,0,0,1,0,0,3,1,0,0,0,0,0,0],"10.2340/00015555-0511"],[20091547,"Debridement of diabetic foot ulcers.","Cochrane Database Syst Rev",2010,"Edwards et al.",0,[0,7,14],[12.63,12.63,12.63],12.63,9,7,7,[0,2,1,0,0,4,0,0,0,0,0,0,0,0,1,1],"10.1002/14651858.CD003556.pub2"],[20131255,"High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study.","Arthritis Rheum",2010,"Terkeltaub et al.",2,[7,11,17],[12.63,12.63,12.63],12.63,7,7,7,[0,1,1,0,0,1,3,0,0,0,0,1,0,0,0,0],"10.1002/art.27327"],[20179267,"Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis.","J Natl Cancer Inst",2010,"Mocellin et 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al.",3,[12,4,10],[11.85,9.3,9.3],11.85,7,7,7,[0,0,0,0,0,0,1,0,0,2,1,0,0,3,0,0],"10.1016/j.jaci.2014.07.023"],[27247257,"Allergy tests do not predict food triggers in adult patients with eosinophilic oesophagitis. 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Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.","N Engl J Med",1995,"Charache et al.",2,[10,17],[11.58,11.58],11.58,7,7,6,[0,0,0,2,2,0,0,1,1,0,1,0,0,0,0,0],"10.1056/NEJM199505183322001"],[9457093,"Randomised trial to assess safety and fetal outcome of early and midtrimester amniocentesis. The Canadian Early and Mid-trimester Amniocentesis Trial (CEMAT) Group.","Lancet",1998,"",2,[17,13],[9.77,1.0],11.58,8,7,7,[1,0,2,0,0,2,1,0,0,0,2,0,0,0,0,0],""],[11380742,"Reducing delirium after hip fracture: a randomized trial.","J Am Geriatr Soc",2001,"Marcantonio et al.",2,[5,6,13],[8.47,8.47,2.69],11.58,7,7,6,[2,0,0,0,2,1,0,0,1,0,0,0,0,1,0,0],"10.1046/j.1532-5415.2001.49108.x"],[15629600,"The role of radiotherapy in the treatment of malignant salivary gland tumors.","Int J Radiat Oncol Biol Phys",2005,"Terhaard et al.",7,[16,1],[11.58,9.17],11.58,7,7,6,[0,0,0,0,0,2,0,0,0,0,0,2,1,1,0,1],"10.1016/j.ijrobp.2004.03.018"],[15805342,"Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addiction.","Pediatrics",2005,"Moolchan et al.",2,[6],[8.47],11.58,7,7,6,[1,2,0,1,2,0,0,0,0,0,0,0,0,0,1,0],"10.1542/peds.2004-1894"],[16284584,"Transdermal fentanyl versus sustained release oral morphine in strong-opioid naïve patients with chronic low back 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A randomized, controlled trial on initial respiratory support via nasopharyngeal tube.","Acta Paediatr",2005,"Lindner et al.",2,[17,3],[9.48,1.0],11.38,8,6,7,[1,0,0,0,2,1,1,0,0,0,1,0,0,0,0,1],"10.1111/j.1651-2227.2005.tb18431.x"],[16740817,"Effects of breast milk on the severity and outcome of neonatal abstinence syndrome among infants of drug-dependent mothers.","Pediatrics",2006,"Abdel-Latif et al.",5,[6,17],[11.38,4.65],11.38,7,6,6,[0,1,0,0,0,0,1,0,1,1,0,0,1,0,1,0],"10.1542/peds.2005-1561"],[16814064,"Sub-Tenon's anesthesia with aspirin, warfarin, and clopidogrel.","J Cataract Refract Surg",2006,"Kumar et al.",5,[0,15,5],[7.22,1.0,0.0],11.38,8,6,6,[1,1,0,1,0,0,1,0,0,0,0,2,0,1,0,0],"10.1016/j.jcrs.2006.02.035"],[17166990,"Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma.","Chest",2006,"Bisgaard et al.",2,[3,12],[11.38,11.38],11.38,6,6,6,[0,0,1,1,1,0,0,0,0,1,0,0,0,1,0,1],"10.1378/chest.130.6.1733"],[18199861,"Iron-overload-related disease in HFE hereditary hemochromatosis.","N Engl J Med",2008,"Allen et al.",5,[7,17,4],[11.38,11.38,1.0],11.38,6,6,6,[1,0,0,0,0,1,0,0,1,0,0,1,1,1,0,0],"10.1056/NEJMoa073286"],[18384586,"The Confusion Assessment Method: a systematic review of current usage.","J Am Geriatr Soc",2008,"Wei et al.",1,[5,6],[6.77,9.02],11.38,6,6,6,[0,1,1,0,1,1,0,0,0,0,0,0,0,1,1,0],"10.1111/j.1532-5415.2008.01674.x"],[20131246,"Effectiveness of rituximab treatment in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled trial.","Arthritis Rheum",2010,"Meijer et al.",2,[11,15,16],[11.38,11.38,11.38],11.38,6,6,6,[0,0,0,0,1,0,1,0,1,1,0,0,0,0,1,1],"10.1002/art.27314"],[20818887,"Ecallantide for the treatment of acute attacks in hereditary angioedema.","N Engl J Med",2010,"Cicardi et al.",2,[0,12,14],[11.38,11.38,11.38],11.38,8,6,6,[1,2,1,1,0,0,0,2,0,0,0,1,0,0,0,0],"10.1056/NEJMoa0905079"],[23264337,"Efficacy of rituximab in systemic manifestations of primary Sjogren's syndrome: results in 78 patients of the AutoImmune and Rituximab registry.","Ann Rheum Dis",2013,"Gottenberg et al.",5,[11,15,16],[11.38,9.02,9.02],11.38,6,6,6,[0,0,0,0,1,0,1,0,1,1,0,0,0,0,1,1],"10.1136/annrheumdis-2012-202293"],[25738669,"Valganciclovir for symptomatic congenital cytomegalovirus disease.","N Engl J Med",2015,"Kimberlin et al.",2,[5,16,2],[6.77,6.77,4.65],11.38,6,6,6,[0,0,0,0,0,1,1,0,0,0,0,0,1,1,1,1],"10.1056/NEJMoa1404599"],[30449625,"Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.","Lancet",2019,"Gillison et al.",2,[1,16],[11.38,6.2],11.38,7,6,6,[0,0,0,0,0,0,0,0,0,1,1,1,0,1,2,1],"10.1016/S0140-6736(18)32779-X"],[15315995,"Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: Treatment for Adolescents With Depression Study (TADS) randomized controlled trial.","JAMA",2004,"March et al.",2,[6],[11.31],11.31,9,7,5,[0,1,0,0,1,2,0,1,1,0,0,1,1,0,0,0],"10.1001/jama.292.7.807"],[11842293,"Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).","J Allergy Clin Immunol",2002,"Möller et al.",2,[12,3,16],[11.27,10.52,10.52],11.27,8,8,5,[2,0,0,1,1,0,2,0,0,0,0,0,0,2,0,0],"10.1067/mai.2002.121317"],[7277110,"Physiologic responses to prolonged and slow-rise inflation in the resuscitation of the asphyxiated newborn infant.","J Pediatr",1981,"Vyas et al.",7,[17],[10.34],11.25,9,9,5,[3,0,0,0,3,1,1,0,0,0,0,0,0,0,1,0],"10.1016/s0022-3476(81)80279-x"],[2871296,"Relation of infant heart to sternum: its significance in cardiopulmonary resuscitation.","Lancet",1986,"Phillips et al.",7,[0,17],[8.12,9.17],11.11,10,9,5,[2,0,0,0,2,0,0,0,0,0,0,0,0,0,4,1],"10.1016/s0140-6736(86)91284-5"],[21526923,"Ranibizumab and bevacizumab for neovascular age-related macular degeneration.","N Engl J Med",2011,"Martin et al.",2,[15],[7.97],11.05,7,7,5,[0,0,0,2,0,0,1,1,0,1,1,0,0,0,1,0],"10.1056/NEJMoa1102673"],[6367724,"The Wisconsin epidemiologic study of diabetic retinopathy. 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Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years.","Arch Ophthalmol",1984,"Klein et al.",7,[0,7,15],[8.71,9.86,6.16],11.04,9,6,5,[1,1,1,1,0,0,1,1,0,1,1,0,0,0,0,0],"10.1001/archopht.1984.01040030398010"],[12637607,"Factors associated with the development of peanut allergy in childhood.","N Engl J Med",2003,"Lack et al.",5,[12,14],[11.04,3.39],11.04,8,6,5,[0,0,1,1,0,0,1,1,1,1,0,1,0,0,1,0],"10.1056/NEJMoa013536"],[16197464,"Diagnosis of Hymenoptera venom allergy.","Allergy",2005,"Biló et al.",6,[12],[10.87],10.87,7,7,5,[2,0,1,0,0,1,0,1,1,0,0,0,0,1,0,0],"10.1111/j.1398-9995.2005.00963.x"],[18974308,"Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.","N Engl J Med",2008,"Walkup et al.",2,[6],[8.54],10.87,7,7,5,[0,1,0,0,1,1,0,1,1,2,0,0,0,0,0,0],"10.1056/NEJMoa0804633"],[22727177,"Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular 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esophageal intraepithelial eosinophils in children with eosinophilic esophagitis.","Gastroenterology",2011,"Assa'ad et al.",2,[4,10,12],[10.86,10.86,10.86],10.86,7,7,6,[0,0,1,0,0,0,0,0,0,1,0,0,0,2,3,0],"10.1053/j.gastro.2011.07.044"],[26584601,"Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis.","Gastroenterology",2016,"Safroneeva et al.",5,[4,10,12],[10.86,10.16,10.16],10.86,9,7,6,[0,0,0,0,0,0,0,0,0,2,0,0,0,2,2,1],"10.1053/j.gastro.2015.11.004"],[33000465,"Tralokinumab for moderate-to-severe atopic dermatitis: results from two 52-week, randomized, double-blind, multicentre, placebo-controlled phase III trials (ECZTRA 1 and ECZTRA 2).","Br J Dermatol",2021,"Wollenberg et al.",2,[14,12,17],[10.86,9.17,9.17],10.86,9,7,6,[0,0,0,0,0,0,0,0,0,0,0,2,1,2,4,0],"10.1111/bjd.19574"],[34023009,"Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial.","Lancet",2021,"Reich et al.",2,[12,14,17],[10.86,10.86,10.86],10.86,8,7,6,[0,0,0,0,0,0,0,0,0,0,0,1,0,3,3,1],"10.1016/S0140-6736(21)00589-4"],[30395812,"RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis.","Gastroenterology",2019,"Hirano et al.",2,[4,10,12],[10.85,10.85,10.85],10.85,9,7,7,[0,0,0,0,0,0,0,0,0,1,0,0,0,3,3,0],"10.1053/j.gastro.2018.10.051"],[33761207,"Abrocitinib versus Placebo or Dupilumab for Atopic Dermatitis.","N Engl J Med",2021,"Bieber et al.",2,[14,12,17],[10.85,9.3,9.3],10.85,8,7,7,[0,0,0,0,0,0,0,0,0,0,0,1,0,3,4,0],"10.1056/NEJMoa2019380"],[7894481,"Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease--a contiguous gene syndrome.","Nat Genet",1994,"Brook-Carter et al.",7,[17,8],[10.83,9.02],10.83,6,6,6,[0,0,0,0,1,2,0,0,1,1,0,0,0,0,1,0],"10.1038/ng1294-328"],[7908078,"Evaluation of ultrasonographic diagnostic criteria for autosomal dominant polycystic kidney disease 1.","Lancet",1994,"Ravine et al.",7,[8,17],[10.83,10.83],10.83,7,6,6,[0,0,0,1,1,2,0,0,1,0,0,0,0,0,1,0],"10.1016/s0140-6736(94)92026-5"],[11730446,"Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU).","JAMA",2001,"Ely et al.",5,[6,5],[8.47,6.2],10.83,6,6,6,[0,0,2,0,1,1,0,0,0,1,0,1,0,0,0,0],"10.1001/jama.286.21.2703"],[12482166,"Bell's palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies.","Acta Otolaryngol Suppl",2002,"Peitersen",6,[5,16,2],[10.83,10.83,9.02],10.83,6,6,6,[0,1,1,1,0,0,1,0,0,0,0,0,0,2,0,0],""],[15051194,"Comparison of preschool vision screening tests as administered by licensed eye care professionals in the Vision In Preschoolers Study.","Ophthalmology",2004,"Schmidt et al.",5,[15,5],[10.83,6.77],10.83,6,6,6,[0,2,0,0,1,0,1,1,0,0,0,0,1,0,0,0],"10.1016/j.ophtha.2004.01.022"],[15475780,"Development and validation of the voice handicap index-10.","Laryngoscope",2004,"Rosen et al.",5,[3,16,5],[6.2,6.2,2.69],10.83,6,6,6,[0,0,1,0,0,1,0,2,0,0,0,1,0,0,0,1],"10.1097/00005537-200409000-00009"],[15625332,"Pegaptanib for neovascular age-related macular degeneration.","N Engl J Med",2004,"Gragoudas et al.",2,[15],[6.77],10.83,6,6,6,[0,1,0,2,0,1,0,0,0,1,0,0,0,1,0,0],"10.1056/NEJMoa042760"],[15858186,"Hemochromatosis and iron-overload screening in a racially diverse population.","N Engl J Med",2005,"Adams et al.",7,[7,17],[10.83,10.83],10.83,6,6,6,[1,0,0,0,0,0,0,0,1,0,0,2,1,1,0,0],"10.1056/NEJMoa041534"],[16100213,"Etanercept for refractory ocular sarcoidosis: results of a double-blind randomized trial.","Chest",2005,"Baughman et al.",2,[10,12,15],[2.69,2.69,2.69],10.83,6,6,6,[1,1,0,2,0,0,1,0,0,0,1,0,0,0,0,0],"10.1378/chest.128.2.1062"],[16935684,"Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys.","Lancet",2006,"Asher et al.",5,[3,12,16],[6.2,6.2,6.2],10.83,6,6,6,[0,0,1,0,1,0,2,1,0,0,0,0,0,0,1,0],"10.1016/S0140-6736(06)69283-0"],[17507703,"Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma.","N Engl J Med",2007,"Papi et al.",2,[3,12],[10.83,10.83],10.83,6,6,6,[0,1,0,1,0,0,0,0,0,2,0,1,1,0,0,0],"10.1056/NEJMoa063861"],[18071169,"QT-interval effects of methadone, levomethadyl, and buprenorphine in a randomized trial.","Arch Intern Med",2007,"Wedam et al.",7,[6],[9.02],10.83,6,6,6,[2,0,0,1,0,1,0,0,0,0,0,0,0,1,0,1],"10.1001/archinte.167.22.2469"],[18195192,"One-year health care costs associated with delirium in the elderly population.","Arch Intern Med",2008,"Leslie et al.",7,[5,6],[9.02,9.02],10.83,6,6,6,[0,0,0,0,1,0,0,0,0,0,1,1,0,2,0,1],"10.1001/archinternmed.2007.4"],[18276741,"Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study.","Ann Rheum Dis",2008,"Dass et al.",2,[11,15,16],[10.83,9.02,9.02],10.83,6,6,6,[2,0,0,0,1,0,0,0,1,1,0,0,0,0,1,0],"10.1136/ard.2007.083865"],[18314433,"Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial.","JAMA",2008,"Brent et al.",2,[6],[10.83],10.83,6,6,6,[0,1,0,0,2,0,1,1,0,0,0,0,1,0,0,0],"10.1001/jama.299.8.901"],[18337601,"Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose.","N Engl J Med",2008,"Chung et al.",5,[12],[10.83],10.83,6,6,6,[0,0,0,1,0,1,1,0,0,0,0,1,2,0,0,0],"10.1056/NEJMoa074943"],[18718440,"Comparison of antibiotics with placebo for treatment of acute sinusitis: a meta-analysis of randomised controlled trials.","Lancet Infect Dis",2008,"Falagas et al.",0,[2,3,16],[10.83,10.83,10.83],10.83,7,6,6,[0,1,3,1,1,0,0,0,0,0,0,0,0,0,1,0],"10.1016/S1473-3099(08)70202-0"],[19185342,"Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis.","Lancet",2009,"Cipriani et al.",0,[6],[10.83],10.83,6,6,6,[1,1,1,0,2,0,0,0,0,0,0,0,1,0,0,0],"10.1016/S0140-6736(09)60046-5"],[19392907,"Prevalence and clinical relevance of corrected QT interval prolongation during methadone and buprenorphine treatment: a mortality assessment study.","Addiction",2009,"Anchersen et al.",7,[6,0,17],[8.47,4.65,4.65],10.83,6,6,6,[1,1,0,2,0,1,0,0,0,0,0,0,0,0,0,1],"10.1111/j.1360-0443.2009.02549.x"],[19482744,"Efficacy of pneumococcal vaccination in children younger than 24 months: a meta-analysis.","Pediatrics",2009,"Pavia et al.",0,[2,16,3],[1.0,8.47,1.0],10.83,7,6,6,[1,1,2,0,0,0,0,0,0,0,0,1,1,0,0,0],"10.1542/peds.2008-3422"],[20070234,"Factors associated with mother-to-child transmission of HIV-1 despite a maternal viral load <500 copies/ml at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS CO1).","Clin Infect Dis",2010,"Tubiana et al.",5,[2,9,12],[10.83,10.83,10.83],10.83,6,6,6,[1,0,1,2,1,0,0,0,0,0,0,0,0,1,0,0],"10.1086/650005"],[20824837,"Acamprosate for alcohol dependence.","Cochrane Database Syst Rev",2010,"Rösner et al.",0,[6],[9.02],10.83,6,6,6,[1,2,0,0,0,0,0,0,0,0,0,0,1,1,0,1],"10.1002/14651858.CD004332.pub2"],[20980427,"Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study.","Diabetes Care",2010,"Massin et al.",2,[15,0,7],[9.02,9.02,9.02],10.83,8,6,6,[0,1,2,2,0,1,1,0,0,0,0,0,0,0,0,0],"10.2337/dc10-0493"],[21459216,"Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema.","Ophthalmology",2011,"Campochiaro et al.",2,[15,0,7],[10.83,9.02,9.02],10.83,6,6,6,[0,0,2,1,0,1,1,0,0,1,0,0,0,0,0,0],"10.1016/j.ophtha.2010.12.028"],[22134787,"Transient PPI responsive esophageal eosinophilia may be a clinical sub-phenotype of pediatric eosinophilic esophagitis.","Dig Dis Sci",2012,"Dohil et al.",7,[4,10,12],[10.83,10.83,10.83],10.83,6,6,6,[0,0,1,1,0,1,0,1,0,0,0,0,0,2,0,0],"10.1007/s10620-011-1991-5"],[22362253,"Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencing.","Obstet Gynecol",2012,"Bianchi et al.",3,[17],[10.83],10.83,7,6,6,[0,0,2,0,2,1,1,0,0,0,1,0,0,0,0,0],"10.1097/AOG.0b013e31824fb482"],[22742782,"Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18.","Am J Obstet Gynecol",2012,"Norton et al.",5,[17,5],[10.83,4.65],10.83,7,6,6,[0,0,2,0,2,1,1,0,0,0,1,0,0,0,0,0],"10.1016/j.ajog.2012.05.021"],[23381017,"Elemental diet induces histologic response in adult eosinophilic esophagitis.","Am J Gastroenterol",2013,"Peterson et al.",3,[4,10,12],[10.83,10.83,10.83],10.83,6,6,6,[0,0,0,0,0,0,1,0,0,1,0,0,0,2,1,1],"10.1038/ajg.2012.468"],[23399553,"Randomized controlled trial comparing aerosolized swallowed fluticasone to esomeprazole for esophageal eosinophilia.","Am J Gastroenterol",2013,"Moawad et al.",2,[4,10,12],[10.83,10.83,10.83],10.83,6,6,6,[0,0,0,0,0,1,0,1,0,1,0,0,0,2,1,0],"10.1038/ajg.2012.443"],[24030475,"The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders.","Am J Psychiatry",2013,"Pacchiarotti et al.",7,[6],[10.83],10.83,7,6,6,[0,0,0,0,3,1,0,1,0,0,1,0,0,1,0,0],"10.1176/appi.ajp.2013.13020185"],[24053982,"Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 Iinternational Tuberous Sclerosis Complex Consensus Conference.","Pediatr Neurol",2013,"Northrup et al.",4,[1,5,17],[10.83,10.83,10.83],10.83,6,6,6,[0,0,0,1,0,1,0,0,1,1,0,0,2,0,0,0],"10.1016/j.pediatrneurol.2013.08.001"],[24286296,"Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study.","Arthritis Res Ther",2013,"Carubbi et al.",5,[11,15,16],[10.83,9.02,9.02],10.83,6,6,6,[0,0,0,0,1,0,2,0,1,1,0,0,0,0,0,1],"10.1186/ar4359"],[24813969,"The role of brain sparing in the prediction of adverse outcomes in intrauterine growth restriction: results of the multicenter PORTO Study.","Am J Obstet Gynecol",2014,"Flood et al.",3,[17,9],[10.83,9.02],10.83,7,6,6,[0,0,0,0,0,0,1,0,1,1,0,0,2,0,1,0],"10.1016/j.ajog.2014.05.008"],[25441638,"Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation.","J Allergy Clin Immunol",2015,"Wen et al.",7,[10,12],[10.83,10.83],10.83,6,6,6,[0,0,0,0,0,1,0,1,0,1,0,0,0,2,1,0],"10.1016/j.jaci.2014.08.043"],[27223595,"Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child.","Addiction",2016,"Zedler et al.",0,[6,9],[10.83,4.04],10.83,7,6,6,[0,0,0,0,0,0,2,1,0,1,0,0,1,0,0,1],"10.1111/add.13462"],[27918720,"What Is the Best Treatment of Locally Advanced Nasopharyngeal Carcinoma? An Individual Patient Data Network Meta-Analysis.","J Clin Oncol",2017,"Ribassin-Majed et al.",0,[1,16],[10.83,10.83],10.83,9,6,6,[0,0,0,0,0,0,0,2,0,0,3,2,0,0,1,1],"10.1200/JCO.2016.67.4119"],[15474135,"Resuscitation of newborn infants with 100% oxygen or air: a systematic review and meta-analysis.","Lancet",2004,"Davis et al.",0,[17],[9.29],10.71,9,9,4,[3,0,0,0,2,0,1,0,0,1,0,0,0,0,1,1],"10.1016/S0140-6736(04)17189-4"],[12207596,"Intermittent dosing of fluticasone propionate cream for reducing the risk of relapse in atopic dermatitis patients.","Br J Dermatol",2002,"Hanifin et al.",2,[12,14,17],[10.69,10.69,10.69],10.69,10,7,4,[0,0,1,0,0,2,0,1,1,0,0,2,0,1,1,1],"10.1046/j.1365-2133.2002.05006.x"],[16172203,"Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.","N Engl J Med",2005,"Lieberman et al.",2,[6],[8.37],10.68,8,6,5,[1,1,2,0,1,0,0,0,1,1,0,0,1,0,0,0],"10.1056/NEJMoa051688"],[16490473,"Hereditary angioedema: new findings concerning symptoms, affected organs, and course.","Am J Med",2006,"Bork et al.",5,[0,12,14],[10.68,10.68,10.68],10.68,8,6,5,[1,1,1,1,0,0,0,2,0,0,0,1,0,0,0,1],"10.1016/j.amjmed.2005.09.064"],[17096020,"Risk of lymphoma following exposure to calcineurin inhibitors and topical steroids in patients with atopic dermatitis.","J Invest Dermatol",2007,"Arellano et al.",5,[14,12,17],[10.68,9.48,9.48],10.68,9,6,5,[0,0,0,1,1,3,0,0,1,0,0,1,0,0,1,1],"10.1038/sj.jid.5700622"],[18637898,"A 4-year follow-up study of atopic dermatitis therapy with 0.1% tacrolimus ointment in children and adult patients.","Br J Dermatol",2008,"Reitamo et al.",7,[12,14,17],[10.68,10.68,10.68],10.68,9,6,5,[0,0,0,0,0,2,0,1,1,0,0,2,0,1,1,1],"10.1111/j.1365-2133.2008.08747.x"],[21210483,"Challenges in the diagnosis of fetal non-chromosomal abnormalities at 11-13 weeks.","Prenat Diagn",2011,"Syngelaki et al.",6,[17],[10.68],10.68,8,6,5,[0,0,2,0,1,0,0,1,0,1,1,1,0,1,0,0],"10.1002/pd.2642"],[15144477,"Late eczematous reactions to food in children with atopic dermatitis.","Clin Exp Allergy",2004,"Breuer et al.",2,[12,14,17],[10.52,6.48,6.48],10.52,7,7,5,[0,0,0,2,0,2,0,1,0,0,0,1,0,1,0,0],"10.1111/j.1365-2222.2004.1953.x"],[16142737,"Rituximab treatment in patients with primary Sjögren's syndrome: an open-label phase II study.","Arthritis Rheum",2005,"Pijpe et al.",3,[11,15,16],[10.52,7.97,7.97],10.52,7,7,5,[3,0,0,0,0,0,1,0,1,1,0,0,0,0,1,0],"10.1002/art.21260"],[17444560,"Discordance in nuchal translucency thickness in the prediction of severe twin-to-twin transfusion syndrome.","Ultrasound Obstet Gynecol",2007,"Kagan et al.",7,[17,9,10],[9.77,4.65,2.69],10.52,8,7,5,[0,0,1,0,0,4,1,0,0,1,0,0,0,1,0,0],"10.1002/uog.4006"],[31860457,"Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis.","Lancet Psychiatry",2020,"Pillinger et al.",0,[6],[10.41],10.41,8,8,5,[0,0,0,0,0,0,0,0,0,0,0,1,2,1,0,4],"10.1016/S2215-0366(19)30416-X"],[18626304,"Primary Sjögren syndrome in Spain: clinical and immunologic expression in 1010 patients.","Medicine (Baltimore)",2008,"Ramos-Casals et al.",5,[11,15,16],[10.36,8.46,8.46],10.36,8,8,4,[0,0,0,0,0,0,1,0,1,0,1,1,0,1,3,0],"10.1097/MD.0b013e318181e6af"],[21068690,"Comparison of pseudobinaural hearing to real binaural hearing rehabilitation after cochlear implantation in patients with unilateral deafness and tinnitus.","Otol Neurotol",2011,"Arndt et al.",5,[5,16],[6.32,6.32],10.36,9,8,4,[0,0,0,0,0,0,0,1,2,0,0,1,1,0,2,1],"10.1097/MAO.0b013e3181fcf271"],[10591283,"A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children with ADHD.","Arch Gen Psychiatry",1999,"",2,[6],[8.01],10.34,8,7,5,[2,1,0,0,1,0,0,0,2,2,0,0,0,0,0,0],"10.1001/archpsyc.56.12.1073"],[12816824,"Twice weekly fluticasone propionate added to emollient maintenance treatment to reduce risk of relapse in atopic dermatitis: randomised, double blind, parallel group study.","BMJ",2003,"Berth-Jones et al.",2,[12,14,17],[10.34,10.34,10.34],10.34,10,7,4,[0,0,1,0,0,3,0,1,1,0,0,2,0,1,1,0],"10.1136/bmj.326.7403.1367"],[20855114,"Two-year outcomes of the ranibizumab for edema of the mAcula in diabetes (READ-2) study.","Ophthalmology",2010,"Nguyen et al.",2,[15,0,7],[10.34,10.34,9.02],10.34,9,7,5,[0,1,0,2,0,2,1,0,0,2,0,0,0,0,0,0],"10.1016/j.ophtha.2010.08.016"],[7603703,"The health impact of chronic sinusitis in patients seeking otolaryngologic care.","Otolaryngol Head Neck Surg",1995,"Gliklich et al.",7,[2,3,16],[10.26,10.26,10.26],10.26,8,6,5,[0,1,0,1,1,0,0,1,0,0,0,1,0,0,2,0],"10.1016/S0194-59989570152-4"],[9420337,"Relation between therapy for hyperthyroidism and the course of Graves' ophthalmopathy.","N Engl J Med",1998,"Bartalena et al.",2,[15,7],[1.41,10.26],10.26,8,6,6,[1,0,1,0,0,1,0,2,0,0,0,0,0,1,1,0],"10.1056/NEJM199801083380201"],[9481027,"Prevalence of IgE-mediated food allergy among children with atopic dermatitis.","Pediatrics",1998,"Eigenmann et al.",3,[12,14,17],[10.26,3.74,3.74],10.26,6,6,5,[0,0,1,0,1,1,1,1,0,0,0,1,0,0,0,0],"10.1542/peds.101.3.e8"],[9927101,"Pilocarpine tablets for the treatment of dry mouth and dry eye symptoms in patients with Sjögren syndrome: a randomized, placebo-controlled, fixed-dose, multicenter trial. P92-01 Study Group.","Arch Intern Med",1999,"Vivino et al.",2,[15,16,11],[7.97,5.78,3.74],10.26,6,6,5,[0,0,0,1,1,0,1,0,1,0,0,0,1,0,1,0],"10.1001/archinte.159.2.174"],[11754675,"Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial.","JAMA",2001,"Dolor et al.",2,[2,3,16],[10.26,10.26,10.26],10.26,7,6,5,[0,2,1,1,1,0,0,1,0,0,0,0,0,0,1,0],"10.1001/jama.286.24.3097"],[15122554,"Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases.","J Oral Maxillofac Surg",2004,"Ruggiero et al.",5,[16,13],[7.97,10.26],10.26,6,6,5,[1,1,0,1,0,0,0,0,1,0,0,0,1,1,0,0],"10.1016/j.joms.2004.02.004"],[16522415,"Prevalence and management of late fetal complications following successful selective laser coagulation of chorionic plate anastomoses in twin-to-twin transfusion syndrome.","Am J Obstet Gynecol",2006,"Robyr et al.",7,[17,10,9],[10.26,10.26,4.65],10.26,7,6,5,[1,0,1,0,1,1,0,0,0,0,0,0,1,1,0,0],"10.1016/j.ajog.2005.08.069"],[17099028,"Interstitial lung disease in primary Sjögren syndrome.","Chest",2006,"Parambil et al.",5,[3,11,15],[7.97,6.77,2.69],10.26,8,6,6,[0,0,0,0,1,0,0,0,0,0,1,0,2,1,1,1],"10.1378/chest.130.5.1489"],[18056902,"Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial.","JAMA",2007,"Williamson et al.",2,[2,3,16],[10.26,10.26,10.26],10.26,7,6,5,[0,2,1,1,1,0,0,1,0,0,0,0,0,0,1,0],"10.1001/jama.298.21.2487"],[18480098,"Schizophrenia: a concise overview of incidence, prevalence, and mortality.","Epidemiol Rev",2008,"McGrath et al.",6,[6],[10.26],10.26,6,6,5,[1,0,0,0,0,1,0,1,0,1,0,1,0,0,0,1],"10.1093/epirev/mxn001"],[18620743,"Tolerance to extensively heated milk in children with cow's milk allergy.","J Allergy Clin Immunol",2008,"Nowak-Wegrzyn et al.",7,[12],[10.26],10.26,7,6,6,[1,2,0,1,0,1,1,0,0,1,0,0,0,0,0,0],"10.1016/j.jaci.2008.05.043"],[19723755,"Thyroid-associated ophthalmopathy after treatment for Graves' hyperthyroidism with antithyroid drugs or iodine-131.","J Clin Endocrinol Metab",2009,"Träisk et al.",2,[7,15,17],[10.26,3.25,1.0],10.26,8,6,6,[1,0,1,0,0,1,0,2,0,0,0,0,1,0,1,0],"10.1210/jc.2009-0747"],[21245183,"Use of florbetapir-PET for imaging beta-amyloid pathology.","JAMA",2011,"Clark et al.",5,[5,6],[7.97,7.97],10.26,7,6,5,[0,1,0,0,1,1,0,0,0,1,0,0,0,1,2,0],"10.1001/jama.2010.2008"],[21324520,"Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.","Lancet",2011,"Martinez et al.",2,[3,12],[10.26,10.26],10.26,6,6,5,[0,1,0,1,0,1,0,0,0,1,0,0,1,1,0,0],"10.1016/S0140-6736(10)62145-9"],[21764136,"Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion twelve-month study results.","Ophthalmology",2011,"Haller et al.",2,[15,0],[10.26,4.65],10.26,7,6,5,[0,0,1,0,1,0,1,0,1,1,0,0,1,0,0,0],"10.1016/j.ophtha.2011.05.014"],[22111863,"Results of ambulatory pH monitoring do not reliably predict response to therapy in patients with eosinophilic oesophagitis.","Aliment Pharmacol Ther",2012,"Francis et al.",3,[4,10,12],[10.26,10.26,10.26],10.26,6,6,5,[0,0,1,0,0,1,0,1,0,1,0,0,0,1,1,0],"10.1111/j.1365-2036.2011.04922.x"],[22475741,"Swallowed fluticasone improves histologic but not symptomatic response of adults with eosinophilic esophagitis.","Clin Gastroenterol Hepatol",2012,"Alexander et al.",2,[4,10,12],[10.26,10.26,10.26],10.26,6,6,5,[0,0,1,1,0,0,0,0,0,1,0,0,0,1,1,1],"10.1016/j.cgh.2012.03.018"],[22748591,"Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks.","Lancet",2012,"Sax et al.",2,[2,9,12],[10.26,10.26,10.26],10.26,7,6,5,[0,1,1,1,2,0,0,1,0,0,0,0,0,0,1,0],"10.1016/S0140-6736(12)60917-9"],[25282563,"Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention.","J Allergy Clin Immunol",2014,"Simpson et 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al.",6,[2,3,16],[10.16,10.16,10.16],10.16,6,6,6,[1,3,0,1,0,1,0,0,0,0,0,0,0,0,0,0],"10.1128/CMR.17.3.571-580.2004"],[17382123,"Pre-ductal and post-ductal O2 saturation in healthy term neonates after birth.","J Pediatr",2007,"Mariani et al.",5,[0,17],[8.01,9.17],10.16,8,8,4,[3,0,0,0,3,0,0,0,0,0,1,0,0,0,1,0],"10.1016/j.jpeds.2006.12.015"],[18238789,"Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis.","Rheumatology (Oxford)",2008,"Tynjälä et al.",5,[11,15],[10.16,6.2],10.16,6,6,6,[0,2,0,1,0,0,0,0,2,0,0,0,0,0,1,0],"10.1093/rheumatology/kem356"],[18362380,"Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: a meta-analysis of randomized controlled trials.","CMAJ",2008,"Karageorgopoulos et al.",0,[2,3,16],[10.16,10.16,10.16],10.16,7,6,6,[0,3,1,0,2,0,0,0,0,0,0,0,0,0,1,0],"10.1503/cmaj.071157"],[21294901,"Early blood glucose profile and neurodevelopmental outcome at two years in neonatal hypoxic-ischaemic encephalopathy.","BMC Pediatr",2011,"Nadeem et al.",5,[5,0,17],[1.0,10.16,10.16],10.16,7,6,6,[0,0,0,0,0,0,1,0,0,0,1,0,0,0,3,2],"10.1186/1471-2431-11-10"],[22418065,"A novel intranasal therapy of azelastine with fluticasone for the treatment of allergic rhinitis.","J Allergy Clin Immunol",2012,"Carr et al.",2,[3,16,12],[10.16,8.47,7.75],10.16,6,6,6,[0,0,0,1,2,0,2,0,0,0,0,0,0,0,1,0],"10.1016/j.jaci.2012.01.077"],[23382571,"Association between antiretroviral exposure and renal impairment among HIV-positive persons with normal baseline renal function: the D:A:D study.","J Infect Dis",2013,"Ryom et al.",5,[2,9,12],[10.16,10.16,10.16],10.16,7,6,6,[0,0,0,3,2,0,0,0,1,0,0,0,0,0,1,0],"10.1093/infdis/jit043"],[23796196,"Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease.","Am J Respir Crit Care Med",2013,"Knowles et al.",6,[3,0,16],[10.16,6.2,6.2],10.16,6,6,6,[0,0,0,0,0,2,0,0,0,2,1,0,0,1,0,0],"10.1164/rccm.201301-0059CI"],[23810152,"Early regular egg exposure in infants with eczema: A randomized controlled trial.","J Allergy Clin Immunol",2013,"Palmer et al.",2,[12,14],[10.16,0.0],10.16,7,6,7,[0,0,0,0,0,0,1,0,0,1,3,0,0,1,0,0],"10.1016/j.jaci.2013.05.002"],[24890068,"Risks of all-cause and suicide mortality in mental disorders: a meta-review.","World Psychiatry",2014,"Chesney et al.",7,[6],[10.16],10.16,6,6,6,[0,0,0,0,0,0,0,2,0,1,0,0,2,0,0,1],"10.1002/wps.20128"],[29114830,"Comparisons of Interventions for Preventing Falls in Older Adults: A Systematic Review and Meta-analysis.","JAMA",2017,"Tricco et al.",0,[5,15],[1.0,0.0],10.16,6,6,6,[0,0,0,0,0,0,0,2,2,0,0,0,1,0,0,1],"10.1001/jama.2017.15006"],[29905515,"Diagnosis of Primary Ciliary Dyskinesia. 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Review and Individual Participant Data Network Meta-Analysis.","JAMA Pediatr",2024,"Sotiropoulos et al.",0,[0,17],[8.64,9.43],9.98,8,8,7,[0,0,0,0,0,0,0,0,0,0,0,0,0,0,4,4],"10.1001/jamapediatrics.2024.1848"],[36449413,"Lecanemab in Early Alzheimer's Disease.","N Engl J Med",2023,"van Dyck et al.",2,[5,6],[7.29,7.29],9.94,8,7,7,[0,0,0,0,0,0,0,0,0,0,0,0,0,1,5,1],"10.1056/NEJMoa2212948"],[27472005,"Fluoride mouthrinses for preventing dental caries in children and adolescents.","Cochrane Database Syst Rev",2016,"Marinho et al.",0,[16],[6.84],9.87,7,7,5,[0,0,0,0,0,0,2,0,1,0,0,0,0,0,1,3],"10.1002/14651858.CD002284.pub2"],[28864073,"Treatment outcomes after reduction of the target volume of intensity-modulated radiotherapy following induction chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: A prospective, multi-center, randomized clinical trial.","Radiother Oncol",2018,"Yang et 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A systematic review and meta-analysis.","Drug Alcohol Depend",2005,"Torrens et al.",0,[6],[8.47],8.47,5,5,5,[0,2,0,0,1,1,0,1,0,0,0,0,0,0,0,0],"10.1016/j.drugalcdep.2004.09.004"],[15943939,"Buprenorphine versus methadone in the treatment of pregnant opioid-dependent patients: effects on the neonatal abstinence syndrome.","Drug Alcohol Depend",2005,"Jones et al.",2,[6,9,17],[8.47,1.35,0.0],8.47,8,5,6,[3,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1],"10.1016/j.drugalcdep.2004.11.013"],[16717206,"Revised diagnostic criteria for neuromyelitis optica.","Neurology",2006,"Wingerchuk et al.",7,[5,15],[8.47,4.65],8.47,5,5,5,[1,1,2,0,1,0,0,0,0,0,0,0,0,0,0,0],"10.1212/01.wnl.0000216139.44259.74"],[16996615,"Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation.","Ophthalmology",2006,"Galor et al.",5,[15],[4.65],8.47,5,5,5,[2,1,0,1,0,0,0,0,1,0,0,0,0,0,0,0],"10.1016/j.ophtha.2006.04.038"],[17055944,"Antibiotics for acute otitis media: a meta-analysis with individual patient data.","Lancet",2006,"Rovers et al.",0,[16],[8.47],8.47,5,5,5,[0,0,2,0,0,0,1,0,1,0,0,0,0,0,1,0],"10.1016/S0140-6736(06)69606-2"],[17592920,"Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials.","J Clin Psychiatry",2007,"Crossley et al.",0,[6],[8.47],8.47,5,5,5,[0,1,1,1,2,0,0,0,0,0,0,0,0,0,0,0],"10.4088/jcp.v68n0617"],[17907169,"Do tumor necrosis factor inhibitors cause uveitis? 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al.",7,[11,15],[7.75,6.2],7.75,5,5,5,[0,2,0,1,0,0,0,0,2,0,0,0,0,0,0,0],"10.1111/j.1442-9071.2005.01062.x"],[16461435,"Tumour necrosis factor alpha inhibitors in the treatment of childhood uveitis.","Rheumatology (Oxford)",2006,"Saurenmann et al.",5,[15],[6.2],7.75,5,5,5,[0,2,0,1,0,0,0,0,2,0,0,0,0,0,0,0],"10.1093/rheumatology/kel030"],[16545455,"Favorable response to high-dose infliximab for refractory childhood uveitis.","Ophthalmology",2006,"Kahn et al.",5,[15],[7.75],7.75,6,5,5,[0,1,0,1,0,0,0,0,3,0,0,0,0,0,0,0],"10.1016/j.ophtha.2006.01.005"],[17011337,"Adalimumab therapy for childhood uveitis.","J Pediatr",2006,"Vazquez-Cobian et al.",3,[15],[6.2],7.75,5,5,5,[0,2,0,1,0,0,0,0,2,0,0,0,0,0,0,0],"10.1016/j.jpeds.2006.04.058"],[17068061,"Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis.","Ann Rheum Dis",2007,"Tynjälä et 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